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10 results on '"Guillem, Olivier"'

1. PREDOMOS study, impact of a social intervention program for socially isolated elderly cancer patients: update to the study protocol for a randomized controlled trial

Author

Couderc, Anne-Laure, Nouguerède, Emilie, Baumstarck, Karine, Loubière, Sandrine, Le Caer, Hervé, Guillem, Olivier, Rousseau, Frédérique, Greillier, Laurent, Norguet-Monnereau, Emmanuelle, Cecile, Maud, Boulahssass, Rabia, Le Caer, Françoise, Tournier, Sandrine, Butaud, Chantal, Guillet, Pierre, Nahon, Sophie, Kirscher, Sylvie, Diaz, Nadine, Morando, Claire, Villani, Patrick, Auquier, Pascal, and Daumas, Aurélie

Published
2019
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2. PREDOMOS study, impact of a social intervention program for socially isolated elderly cancer patients: study protocol for a randomized controlled trial

Author

Crétel-Durand, Elodie, Nouguerède, Emilie, Le Caer, Hervé, Rousseau, Frédérique, Retornaz, Frédérique, Guillem, Olivier, Couderc, Anne-Laure, Greillier, Laurent, Norguet, Emmanuelle, Cécile, Maud, Boulahssass, Rabia, Le Caer, Francoise, Tournier, Sandrine, Butaud, Chantal, Guillet, Pierre, Nahon, Sophie, Poudens, Laure, Kirscher, Sylvie, Loubière, Sandrine, Diaz, Nadine, Dhorne, Jean, Auquier, Pascal, and Baumstarck, Karine

Published
2017
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3. Prevalence and prognostic impact of cachexia among older patients with cancer: a nationwide cross‐sectional survey (NutriAgeCancer)

Author

Poisson, Johanne, primary, Martinez‐Tapia, Claudia, additional, Heitz, Damien, additional, Geiss, Romain, additional, Albrand, Gilles, additional, Falandry, Claire, additional, Gisselbrecht, Mathilde, additional, Couderc, Anne‐Laure, additional, Boulahssass, Rabia, additional, Liuu, Evelyne, additional, Boudou‐Rouquette, Pascaline, additional, Chah Wakilian, Anne, additional, Gaxatte, Cedric, additional, Pamoukdjian, Fréderic, additional, de Decker, Laure, additional, Antoine, Valery, additional, Cattenoz, Catherine, additional, Solem‐Laviec, Heidi, additional, Guillem, Olivier, additional, Medjenah, Hayat, additional, Natella, Pierre André, additional, Canouï‐Poitrine, Florence, additional, Laurent, Marie, additional, and Paillaud, Elena, additional

Published
2021
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5. EWOC-1: A randomized trial to evaluate the feasibility of three different first-line chemotherapy regimens for vulnerable elderly women with ovarian cancer (OC): A GCIG-ENGOT-GINECO study.

Author

Falandry, Claire, primary, Savoye, Aude Marie, additional, Stefani, Laetitia, additional, Tinquaut, Fabien, additional, Lorusso, Domenica, additional, Herrstedt, Jorn, additional, Bourbouloux, Emmanuelle, additional, Floquet, Anne, additional, Brachet, Pierre Emmanuel, additional, Zannetti, Alain, additional, Mouret-Reynier, Marie-Ange, additional, Sverdlin, Robert, additional, D'hondt, Veronique, additional, Guillem, Olivier, additional, Cojocarasu, Oana, additional, Venat-Bouvet, Laurence, additional, Rousseau, Frederique, additional, Lortholary, Alain, additional, Pujade-Lauraine, Eric, additional, and Freyer, Gilles, additional

Published
2019
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6. Predicting chemotherapy toxicity and death in older adults with colon cancer: Results of MOST (Massilia Oncologic Senior Tests) study.

Author

Retornaz, Frédérique, primary, Guillem, Olivier, additional, Gholam, Dany, additional, Codoul, Jean-François, additional, Brativesic, Cécile, additional, Morvan, Francois, additional, Rinaldi, Yves, additional, Barriere, Nicolas, additional, Nahon, Sophie, additional, Butaud, Chantal, additional, Guerin, Olivier, additional, Boulahssass, Rabia, additional, Grino, Michel, additional, and Rousseau, Frederique, additional

Published
2018
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7. Additional file 1: of PREDOMOS study, impact of a social intervention program for socially isolated elderly cancer patients: study protocol for a randomized controlled trial

Author

Crétel-Durand, Elodie, Nouguerède, Emilie, Caer, Hervé Le, Rousseau, Frédérique, Retornaz, Frédérique, Guillem, Olivier, Anne-Laure Couderc, Greillier, Laurent, Norguet, Emmanuelle, Cécile, Maud, Boulahssass, Rabia, Francoise Le Caer, Tournier, Sandrine, Butaud, Chantal, Guillet, Pierre, Nahon, Sophie, Poudens, Laure, Kirscher, Sylvie, Loubière, Sandrine, Diaz, Nadine, Dhorne, Jean, Auquier, Pascal, and Baumstarck, Karine

Abstract

SPIRIT checklist items. (DOC 255 kb)

Published
2017
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8. Predicting Chemotherapy Toxicity and Death in Older Adults with Colon Cancer: Results of MOST Study.

Author

Retornaz, Frédérique, Guillem, Olivier, Rousseau, Frédérique, Morvan, Francois, Rinaldi, Yves, Nahon, Sophie, Castagna, Chantal, Boulahssass, Rabia, Grino, Michel, and Gholam, Dany

Subjects
GERIATRIC assessment, BIOMARKERS, CANCER chemotherapy, COGNITION, COLON tumors, DRUG toxicity, FRAIL elderly, GRIP strength, LIFE skills, LONGITUDINAL method, MEDICAL cooperation, METASTASIS, NUTRITION, RESEARCH, RISK assessment, LOGISTIC regression analysis, BODY movement, PHYSICAL activity, DESCRIPTIVE statistics, OLD age
Abstract

Purpose: Older patients with colon cancer (CC) are vulnerable to chemotherapy toxicity and death. Establishing simple scores specific for patients with CC to predict severe chemotoxicity or early death is needed to select the best treatment strategy. Subjects, Materials, and Methods: This prospective multicenter study included patients aged ≥70 years with CC receiving adjuvant or first‐line metastatic chemotherapy. Frailty markers (nutrition, physical activity, energy, mobility, strength), comprehensive geriatric assessment (functional status, comorbidities, falls, nutrition, cognition, and depression), and usual laboratory parameters were collected. Logistic or Cox regression was used to examine at 500 days the association between frailty markers, comprehensive geriatric assessment, laboratory parameters, and grade 3–4 toxicity or death. Results: A total of 97 patients (median age, 79.0 years) received adjuvant (37.1%) or metastatic (62.9%) chemotherapy. During the first 500 days, grade 3–4 toxicity occurred in 49.5%, and 30% died. The predictive model for grade 3–4 toxicity combined (polychemotherapy × 3) + (hypoalbuminemia <32 g/L × 2) + (abnormal grip strength × 1.5) + C‐reactive protein >11 mg/L + Eastern Cooperative Oncology Group performance status (ECOG‐PS), cutoff score >3. The predictive model for death combined (metastasis × 5) + (age × 2) + alkaline phosphatase >100 IU/mL + sex (female) + abnormal grip strength + ECOG‐PS, cutoff score >6. For chemotoxicity prediction, sensitivity was 81.6% and specificity 71.4%. For death prediction, sensitivity was 89.7% and specificity was 83.6%. Conclusion: These simple and efficient "ColonPrediscores" will help to better identify older patients with CC with increased risk of chemotherapy‐related toxicity and/or death. Implications for Practice: The two scores assessed in this study, called "ColonPrediscores", offer a major advantage in that they do not need a previous complete geriatric assessment, which makes them an easy‐to‐use tool in oncologic settings. Colon cancer mainly affects older patients who are at risk for chemotherapy‐related toxicities. This article describes the ColonPrediscores system for identifying patients with in increased risk for toxicity and/or death in this patient group. [ABSTRACT FROM AUTHOR]

Published
2020
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9. First-line systemic treatment with palbociclib in women aged ≥70 years presenting with hormone receptor-positive advanced breast cancer: Results from the PALOMAGE program.

Author

Carola, Elisabeth, Pulido, Marina, Falandry, Claire, Paillaud, Elena, Caillet, Philippe, Tassy, Louis, Bringuier, Michael, Rochette de Lempdes, Godelieve, Grosjean, Jessica, Mina, William, Guillem, Olivier, Jovenin, Nicolas, Desmoulins, Isabelle, Bouteiller, Fanny, Bettache, Dounia, Rifi, Nada, and Brain, Etienne

Published
2023
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10. Frailty markers for prediction of mortality in first-line chemotherapy for colon cancer patients: Results of MOST/ASRO 101 study.

Author

Retornaz, Frederique, primary, Guillem, Olivier, additional, Gholam, Dany, additional, Codoul, Jean francois, additional, Bratisevic, Cecile, additional, Morvan, Francois, additional, Rinaldi, Yves, additional, Barriere, Nicolas, additional, Nahon, Sophie, additional, Butaud, Chantal, additional, Guerin, Olivier, additional, Boulahssass, Rabia, additional, and Rousseau, Frederique, additional

Published
2014
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