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3. Impact of a centre and home-based cardiac rehabilitation program on the quality of life of teenagers and young adults with congenital heart disease: The QUALIREHAB randomized controlled trial

Author

Amédro, P., primary, Gavotto, A., additional, Huguet, H., additional, Souilla, L., additional, Dauphin, C., additional, Dulac, Y., additional, Bouvaist, H., additional, Ovaert, C., additional, Combes, N., additional, Thambo, J.-B., additional, Bonnet, D., additional, Ansquer, H., additional, Cohen, L., additional, Hascoët, S., additional, Picot, M.-C., additional, and Guillaumont, S., additional

Published
2024
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13. Which classification best predicts functional prognosis in children with congenital heart disease?

Author

Gavotto, A., Amedro, P., Ouhab, I., Guillaumont, S., Liard, I., Huguet, H., and Picot, M.C.

Abstract

Despite these advances in paediatric cardiology, the stratification of CHD severity using a simple and reproducible classification has not been established, as can be the NYHA functional class in adult heart failure. Various CHD classifications have been used in CHD, focusing on anatomical lesions, complexity of care, or physiological status, but their prognostic value has not been determined. We aimed to compare the accuracy of the main existing CHD classifications (Uzark, Stout and Bethesda classifications), in the prediction of functional status in children with CHD, as determined by cardiopulmonary fitness. Longitudinal cohort study. The CHD population having had 2 CPET included 296 subjects (n = 129 female). The time between the first (T1) and second CPET (T2) assessments was 4.1 ± 1.6 years. The performance of classifications according to VO 2 max at T1 was better for Uzark classification. The VO 2 max Z-score decreased significantly according to the severity group (groups 1 and 2 > group 3 > group 4) and group 4 had a significant VO 2 max decrease of −6.68 [−10.69; −2.67] mL/kg/min compared to group 1. The prediction of classifications at T2 according to VO 2 max was better for Uzark classification with AUC values of 0.62 [0.55–0.69], compared to 0.59 [0.51–0.66] for Stout and 0.55 [0.48–0.62] for Bethesda (Fig. 1). Among the existing cardiovascular risk classifications for CHD, the Uzark classification appeared to be the most reliable for discriminating the severity of CHD according to exercise capacity and for predicting the VO 2 max impairment than the other classifications tested. This longitudinal study also showed the continued decline in exercise capacity, whatever the CHD, and recalls the interest of regular monitoring to offer care adapted to these patients (such as rehabilitation programs) for primary prevention of the added cardiovascular risks of adulthood. [ABSTRACT FROM AUTHOR]

Published
2024
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24. Reference values of cardiopulmonary exercise test parameters in the contemporary paediatric population.

Author

Gavotto, A., Amedro, P., Guillaumont, S., De La Villeon, G., Vincenti, M., Huguet, H., Picot, M.C., and Mura, T.

Abstract

The evaluation of health status by cardiopulmonary exercise test (CPET) has shown increasing interest in the paediatric population. Our group recently established reference Z-score values for paediatric cycle ergometer VO 2 max, applicable to normal and extreme weights, from a cohort of 1141 healthy children. There are currently no validated reference values for the other CPET parameters in the paediatric population. This study aimed to establish, from the same cohort, reference Z-score values for the main paediatric cycle ergometer CPET parameters, apart from VO 2 max. Cross-sectional study. In total, 909 healthy children aged 5 to 18 years old underwent a CPET. Linear, quadratic, and polynomial mathematical regression equations were applied to identify the best CPET parameters Z-scores, according to anthropometric parameters (sex, age, height, weight, and BMI). This study provided Z-scores for maximal CPET parameters (heart rate, respiratory exchange ratio, workload, and oxygen pulse), submaximal CPET parameters (ventilatory anaerobic threshold, VE/VCO 2 slope, and oxygen uptake efficiency slope), and maximum ventilatory CPET parameters (tidal volume, respiratory rate, breathing reserve, and ventilatory equivalent for CO 2 and O 2) (Fig. 1). This study defined paediatric reference Z-score values for the main cycle ergometer CPET parameters, in addition to the existing reference values for VO 2 max, applicable to children of normal and extreme weights. Providing Z-scores for CPET parameters in the paediatric population should be useful in the follow-up of children with various chronic diseases. Thus, new paediatric research fields are opening up, such as prognostic studies and clinical trials using cardiopulmonary fitness outcomes. [ABSTRACT FROM AUTHOR]

Published
2024
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25. Dermatological manifestations in Noonan syndrome

Author

Bessis, D., primary, Miquel, J., additional, Bourrat, E., additional, Chiaverini, C., additional, Morice‐Picard, F., additional, Abadie, C., additional, Manna, F., additional, Baumann, C., additional, Best, M., additional, Blanchet, P., additional, Bursztejn, A.‐C., additional, Capri, Y., additional, Coubes, C., additional, Giuliano, F., additional, Guillaumont, S., additional, Hadj‐Rabia, S., additional, Jacquemont, M.‐L., additional, Jeandel, C., additional, Lacombe, D., additional, Mallet, S., additional, Mazereeuw‐Hautier, J., additional, Molinari, N., additional, Pallure, V., additional, Pernet, C., additional, Philip, N., additional, Pinson, L., additional, Sarda, P., additional, Sigaudy, S., additional, Vial, Y., additional, Willems, M., additional, Genevievé, D., additional, Verloes, A., additional, and Cavé, H., additional

Published
2019
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26. 努南综合征的皮肤病表现

Author

Bessis, D., primary, Miquel, J., additional, Bourrat, E., additional, Chiaverini, C., additional, Morice‐Picard, F., additional, Abadie, C., additional, Manna, F., additional, Baumann, C., additional, Best, M., additional, Blanchet, P., additional, Bursztejn, A.‐C., additional, Capri, Y., additional, Coubes, C., additional, Giuliano, F., additional, Guillaumont, S., additional, Hadj‐Rabia, S., additional, Jacquemont, M.‐L., additional, Jeandel, C., additional, Lacombe, D., additional, Mallet, S., additional, Mazereeuw‐Hautier, J., additional, Molinari, N., additional, Pallure, V., additional, Pernet, C., additional, Philip, N., additional, Pinson, L., additional, Sarda, P., additional, Sigaudy, S., additional, Vial, Y., additional, Willems, M., additional, Genevievé, D., additional, Verloes, A., additional, and Cavé, H., additional

Published
2019
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28. Speckle tracking echocardiography in children with Duchenne muscular dystrophy: A multicenter controlled cross-sectional study

Author

Amedro, P., primary, Vincenti, M., additional, De La Villeon, G., additional, Lavastre, K., additional, Barrea, C., additional, Guillaumont, S., additional, Bredy, C., additional, Meli, Albano, additional, Cazorla, Olivier, additional, Fauconnier, Jérémy, additional, Meyer, P., additional, Rivier, F., additional, Adda, J., additional, Mura, T., additional, and Lacampagne, Alain, additional

Published
2019
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29. Cardiopulmonary fitness in children with congenital heart diseases versus healthy children: A multicenter cross-sectional study

Author

Rola, M., primary, Gavotto, A., additional, Guillaumont, S., additional, Vincenti, M., additional, Bredy, C., additional, De La Villeon, G., additional, Picot, M.C., additional, Bertet, H., additional, Vandenberghe, D., additional, Werner, O., additional, Ovaert, C., additional, Acar, P., additional, Matecki, S., additional, and Amedro, P., additional

Published
2018
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35. Corrélation entre VO2 et qualité de vie chez l’enfant cardiaque

Author

Amedro, P., primary, Picot, M.C., additional, Stéphane, M., additional, Dorka, R., additional, Bertet, H., additional, Guillaumont, S., additional, Barrea, C., additional, Vincenti, M.-C., additional, De la Villeon, G., additional, Bredy, C., additional, Soulatges, C., additional, Voisin, M., additional, Matecki, S., additional, and Auquier, P., additional

Published
2016
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38. 0350: Correlation between cardio-pulmonary exercise test variables and health-related quality of life among children with congenital heart diseases

Author

Amedro, Pascal, primary, Dorka, Raphael, additional, Moniotte, Stéphane, additional, Picot, Marie-Christine, additional, Bertet, Héléna, additional, Guillaumont, S., additional, Sluys-mans, Thierry, additional, Barrea, Catherine, additional, Matecki, Stefan, additional, Bredy, Charlène, additional, Vincenti, Marie, additional, Soulatges, Camille, additional, and Auquier, Pascal, additional

Published
2016
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39. Redesigning Conditionality

Author

Collier, P., Guillaumont, P., Guillaumont, S., Gunning, J.W., Bird, G., Rowlands, D., and Economics

Published
2007

40. Manifestations dermatologiques des rasopathies : étude observationnelle prospective multicentrique de 85 patients

Author

Pernet, C., primary, Bourrat, E., additional, Miquel, J., additional, Abadie, C., additional, Amedro, P., additional, Baumann, C., additional, Blanchet, P., additional, Chiaverini, C., additional, Coubes, C., additional, Geneviève, D., additional, Guillaumont, S., additional, Hadj-Rabia, S., additional, Hesse, S., additional, Jeandel, C., additional, Mallet, S., additional, Mazereeuw-Hautier, J., additional, Morice-Picard, F., additional, Philip, N., additional, Pinson, L., additional, Sarda, P., additional, Sigaudy, S., additional, Willems, M., additional, Cavé, H., additional, and Bessis, D., additional

Published
2014
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43. Redesigning conditionality

Author

Collier, P., Guillaumont, P., Guillaumont, S., Jan Willem Gunning, Economics, Bird, G., and Rowlands, D.

Subjects
Economics and Econometrics, Sociology and Political Science, Geography, Planning and Development, Development
Published
1997
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45. Characteristics and long-term outcome of non-immune isolated atrioventricular block diagnosed in utero or early childhood: a multicentre study

Author

Baruteau, A.-E., primary, Fouchard, S., additional, Behaghel, A., additional, Mabo, P., additional, Villain, E., additional, Thambo, J.-B., additional, Marcon, F., additional, Gournay, V., additional, Rouault, F., additional, Chantepie, A., additional, Guillaumont, S., additional, Godart, F., additional, Bonnet, C., additional, Fraisse, A., additional, Schleich, J.-M., additional, Lusson, J.-R., additional, Dulac, Y., additional, Leclercq, C., additional, Daubert, J.-C., additional, Schott, J.-J., additional, Le Marec, H., additional, and Probst, V., additional

Published
2011
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