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27 results on '"Gui, Lixuan"'

1. The PGS1 basic helix‐loop‐helix protein regulates Fl3 to impact seed growth and grain yield in cereals

Author

Guo, Xiaojiang, Fu, Yuxin, Lee, Yuh‐Ru Julie, Chern, Mawsheng, Li, Maolian, Cheng, Mengping, Dong, Huixue, Yuan, Zhongwei, Gui, Lixuan, Yin, Junjie, Qing, Hai, Zhang, Chengbi, Pu, Zhien, Liu, Yujiao, Li, Weitao, Li, Wei, Qi, Pengfei, Chen, Guoyue, Jiang, Qiantao, Ma, Jian, Chen, Xuewei, Wei, Yuming, Zheng, Youliang, Wu, Yongrui, Liu, Bo, and Wang, Jirui

Subjects
Agricultural, Veterinary and Food Sciences, Crop and Pasture Production, Biotechnology, 3.3 Nutrition and chemoprevention, Prevention of disease and conditions, and promotion of well-being, Basic Helix-Loop-Helix Transcription Factors, Edible Grain, Gene Expression Regulation, Plant, Oryza, Plant Proteins, Seeds, Triticum, transcription factor, grain weight, grain size, endosperm, Biological Sciences, Technology, Medical and Health Sciences, Agricultural biotechnology, Plant biology
Abstract

Plant transcription factors (TFs), such as basic helix-loop-helix (bHLH) and AT-rich zinc-binding proteins (PLATZ), play critical roles in regulating the expression of developmental genes in cereals. We identified the bHLH protein TaPGS1 (T. aestivum Positive Regulator of Grain Size 1) specifically expressed in the seeds at 5-20 days post-anthesis in wheat. TaPGS1 was ectopically overexpressed (OE) in wheat and rice, leading to increased grain weight (up to 13.81% in wheat and 18.55% in rice lines) and grain size. Carbohydrate and total protein levels also increased. Scanning electron microscopy results indicated that the starch granules in the endosperm of TaPGS1 OE wheat and rice lines were smaller and tightly embedded in a proteinaceous matrix. Furthermore, TaPGS1 was bound directly to the E-box motif at the promoter of the PLATZ TF genes TaFl3 and OsFl3 and positively regulated their expression in wheat and rice. In rice, the OsFl3 CRISPR/Cas9 knockout lines showed reduced average thousand-grain weight, grain width, and grain length in rice. Our results reveal that TaPGS1 functions as a valuable trait-associated gene for improving cereal grain yield.

Published
2022

4. Genetically Determined Plasma Lipid Levels and Risk of Diabetic Retinopathy: A Mendelian Randomization Study

Author

Sobrin, Lucia, Chong, Yong He, Fan, Qiao, Gan, Alfred, Stanwyck, Lynn K, Kaidonis, Georgia, Craig, Jamie E, Kim, Jihye, Liao, Wen-Ling, Huang, Yu-Chuen, Lee, Wen-Jane, Hung, Yi-Jen, Guo, Xiuqing, Hai, Yang, Ipp, Eli, Pollack, Samuela, Hancock, Heather, Price, Alkes, Penman, Alan, Mitchell, Paul, Liew, Gerald, Smith, Albert V, Gudnason, Vilmundur, Tan, Gavin, Klein, Barbara EK, Kuo, Jane, Li, Xiaohui, Christiansen, Mark W, Psaty, Bruce M, Sandow, Kevin, Jensen, Richard A, Klein, Ronald, Cotch, Mary Frances, Wang, Jie Jin, Jia, Yucheng, Chen, Ching J, Chen, Yii-Der Ida, Rotter, Jerome I, Tsai, Fuu-Jen, Hanis, Craig L, Burdon, Kathryn P, Wong, Tien Yin, Cheng, Ching-Yu, Spracklen, Cassandra N, Chen, Peng, Kim, Young Jin, Wang, Xu, Cai, Hui, Li, Shengxu, Long, Jirong, Wu, Ying, Wang, Ya-Xing, Takeuchi, Fumihiko, Wu, Jer-Yuarn, Jung, Keum-Ji, Hu, Cheng, Akiyama, Koichi, Zhang, Yonghong, Moon, Sanghoon, Johnson, Todd A, Li, Huaixing, Dorajoo, Rajkumar, He, Meian, Cannon, Maren E, Roman, Tamara S, Salfati, Elias, Lin, Keng-Hung, Sheu, Wayne HH, Absher, Devin, Adair, Linda S, Assimes, Themistocles L, Aung, Tin, Cai, Qiuyin, Chang, Li-Ching, Chen, Chien-Hsiun, Chien, Li-Hsin, Chuang, Lee-Ming, Chuang, Shu-Chun, Du, Shufa, Fann, Cathy SJ, Feranil, Alan B, Friedlander, Yechiel, Gordon-Larsen, Penny, Gu, Dongfeng, Gui, Lixuan, Guo, Zhirong, Heng, Chew-Kiat, Hixson, James, Hou, Xuhong, Hsiung, Chao Agnes, Hu, Yao, Hwang, Mi Yeong, Hwu, Chii-Min, Isono, Masato, Juang, Jyh-Ming Jimmy, Khor, Chiea-Chuen, Kim, Yun Kyoung, Koh, Woon-Puay, Kubo, Michiaki, and Lee, I-Te

Subjects
Biomedical and Clinical Sciences, Cancer, Prevention, Eye Disease and Disorders of Vision, 2.1 Biological and endogenous factors, Aetiology, Metabolic and endocrine, Aged, Diabetic Retinopathy, Female, Genome-Wide Association Study, Humans, Lipids, Male, Mendelian Randomization Analysis, Middle Aged, Polymorphism, Single Nucleotide, Risk, Asian Genetic Epidemiology Network Consortium, Medical and Health Sciences, Endocrinology & Metabolism, Biomedical and clinical sciences
Abstract

Results from observational studies examining dyslipidemia as a risk factor for diabetic retinopathy (DR) have been inconsistent. We evaluated the causal relationship between plasma lipids and DR using a Mendelian randomization approach. We pooled genome-wide association studies summary statistics from 18 studies for two DR phenotypes: any DR (N = 2,969 case and 4,096 control subjects) and severe DR (N = 1,277 case and 3,980 control subjects). Previously identified lipid-associated single nucleotide polymorphisms served as instrumental variables. Meta-analysis to combine the Mendelian randomization estimates from different cohorts was conducted. There was no statistically significant change in odds ratios of having any DR or severe DR for any of the lipid fractions in the primary analysis that used single nucleotide polymorphisms that did not have a pleiotropic effect on another lipid fraction. Similarly, there was no significant association in the Caucasian and Chinese subgroup analyses. This study did not show evidence of a causal role of the four lipid fractions on DR. However, the study had limited power to detect odds ratios less than 1.23 per SD in genetically induced increase in plasma lipid levels, thus we cannot exclude that causal relationships with more modest effect sizes exist.

Published
2017

5. Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels

Author

Spracklen, Cassandra N, Chen, Peng, Kim, Young Jin, Wang, Xu, Cai, Hui, Li, Shengxu, Long, Jirong, Wu, Ying, Wang, Ya Xing, Takeuchi, Fumihiko, Wu, Jer-Yuarn, Jung, Keum-Ji, Hu, Cheng, Akiyama, Koichi, Zhang, Yonghong, Moon, Sanghoon, Johnson, Todd A, Li, Huaixing, Dorajoo, Rajkumar, He, Meian, Cannon, Maren E, Roman, Tamara S, Salfati, Elias, Lin, Keng-Hung, Guo, Xiuqing, Sheu, Wayne HH, Absher, Devin, Adair, Linda S, Assimes, Themistocles L, Aung, Tin, Cai, Qiuyin, Chang, Li-Ching, Chen, Chien-Hsiun, Chien, Li-Hsin, Chuang, Lee-Ming, Chuang, Shu-Chun, Du, Shufa, Fan, Qiao, Fann, Cathy SJ, Feranil, Alan B, Friedlander, Yechiel, Gordon-Larsen, Penny, Gu, Dongfeng, Gui, Lixuan, Guo, Zhirong, Heng, Chew-Kiat, Hixson, James, Hou, Xuhong, Hsiung, Chao Agnes, Hu, Yao, Hwang, Mi Yeong, Hwu, Chii-Min, Isono, Masato, Juang, Jyh-Ming Jimmy, Khor, Chiea-Chuen, Kim, Yun Kyoung, Koh, Woon-Puay, Kubo, Michiaki, Lee, I-Te, Lee, Sun-Ju, Lee, Wen-Jane, Liang, Kae-Woei, Lim, Blanche, Lim, Sing-Hui, Liu, Jianjun, Nabika, Toru, Pan, Wen-Harn, Peng, Hao, Quertermous, Thomas, Sabanayagam, Charumathi, Sandow, Kevin, Shi, Jinxiu, Sun, Liang, Tan, Pok Chien, Tan, Shu-Pei, Taylor, Kent D, Teo, Yik-Ying, Toh, Sue-Anne, Tsunoda, Tatsuhiko, van Dam, Rob M, Wang, Aili, Wang, Feijie, Wang, Jie, Bin Wei, Wen, Xiang, Yong-Bing, Yao, Jie, Yuan, Jian-Min, Zhang, Rong, Zhao, Wanting, Chen, Yii-Der Ida, Rich, Stephen S, Rotter, Jerome I, Wang, Tzung-Dau, Wu, Tangchun, Lin, Xu, Han, Bok-Ghee, Tanaka, Toshihiro, Cho, Yoon Shin, Katsuya, Tomohiro, and Jia, Weiping

Subjects
Genetics, Human Genome, Atherosclerosis, 2.1 Biological and endogenous factors, Aetiology, Metabolic and endocrine, Adult, Alleles, Asian People, Cholesterol, Ethnicity, Female, Gene Frequency, Genetic Association Studies, Genome-Wide Association Study, Humans, Linkage Disequilibrium, Lipids, Lipoproteins, HDL, Lipoproteins, LDL, Male, Middle Aged, Polymorphism, Single Nucleotide, Quantitative Trait Loci, Triglycerides, White People, Biological Sciences, Medical and Health Sciences, Genetics & Heredity
Abstract

Large-scale meta-analyses of genome-wide association studies (GWAS) have identified >175 loci associated with fasting cholesterol levels, including total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and triglycerides (TG). With differences in linkage disequilibrium (LD) structure and allele frequencies between ancestry groups, studies in additional large samples may detect new associations. We conducted staged GWAS meta-analyses in up to 69,414 East Asian individuals from 24 studies with participants from Japan, the Philippines, Korea, China, Singapore, and Taiwan. These meta-analyses identified (P

Published
2017

6. Genome-Wide Association Study Meta-Analysis of Long-Term Average Blood Pressure in East Asians

Author

Li, Changwei, Kim, Yun Kyoung, Dorajoo, Rajkumar, Li, Huaixing, Lee, I-Te, Cheng, Ching-Yu, He, Meian, Sheu, Wayne H-H, Guo, Xiuqing, Ganesh, Santhi K, He, Jiang, Lee, Juyoung, Liu, Jianjun, Hu, Yao, Rao, Dabeeru C, Tsai, Fuu-Jen, Koh, Jia Yu, Hu, Hua, Liang, Kae-Woei, Palmas, Walter, Hixson, James E, Han, Sohee, Teo, Yik-Ying, Wang, Yiqin, Chen, Jing, Lu, Chieh Hsiang, Zheng, Yingfeng, Gui, Lixuan, Lee, Wen-Jane, Yao, Jie, Gu, Dongfeng, Han, Bok-Ghee, Sim, Xueling, Sun, Liang, Zhao, Jinying, Chen, Chien-Hsiun, Kumari, Neelam, He, Yunfeng, Taylor, Kent D, Raffel, Leslie J, Moon, Sanghoon, Rotter, Jerome I, Ida Chen, Yii-der, Wu, Tangchun, Wong, Tien Yin, Wu, Jer-Yuarn, Lin, Xu, Tai, E-Shyong, Kim, Bong-Jo, and Kelly, Tanika N

Subjects
Biomedical and Clinical Sciences, Cardiovascular Medicine and Haematology, Biotechnology, Genetics, Human Genome, 2.1 Biological and endogenous factors, Aetiology, Cardiovascular, Asian People, Blood Pressure, Asia, Eastern, Female, Genetic Loci, Genome-Wide Association Study, Humans, Male, Phenotype, Polymorphism, Single Nucleotide, arterial pressure, blood pressure, epidemiology, genome-wide association study, Medical Biotechnology, Cardiorespiratory Medicine and Haematology, Cardiovascular System & Hematology, Cardiovascular medicine and haematology
Abstract

BackgroundGenome-wide single marker and gene-based meta-analyses of long-term average (LTA) blood pressure (BP) phenotypes may reveal novel findings for BP.Methods and resultsWe conducted genome-wide analysis among 18 422 East Asian participants (stage 1) followed by replication study of ≤46 629 participants of European ancestry (stage 2). Significant single-nucleotide polymorphisms and genes were determined by a P

Published
2017

7. A pig BodyMap transcriptome reveals diverse tissue physiologies and evolutionary dynamics of transcription

Author

Jin, Long, Tang, Qianzi, Hu, Silu, Chen, Zhongxu, Zhou, Xuming, Zeng, Bo, Wang, Yuhao, He, Mengnan, Li, Yan, Gui, Lixuan, Shen, Linyuan, Long, Keren, Ma, Jideng, Wang, Xun, Chen, Zhengli, Jiang, Yanzhi, Tang, Guoqing, Zhu, Li, Liu, Fei, Zhang, Bo, Huang, Zhiqing, Li, Guisen, Li, Diyan, Gladyshev, Vadim N., Yin, Jingdong, Gu, Yiren, Li, Xuewei, and Li, Mingzhou

Published
2021
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8. Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci

Author

He, Meian, Xu, Min, Zhang, Ben, Liang, Jun, Chen, Peng, Lee, Jong-Young, Johnson, Todd A, Li, Huaixing, Yang, Xiaobo, Dai, Juncheng, Liang, Liming, Gui, Lixuan, Qi, Qibin, Huang, Jinyan, Li, Yanping, Adair, Linda S, Aung, Tin, Cai, Qiuyin, Cheng, Ching-Yu, Cho, Myeong-Chan, Cho, Yoon Shin, Chu, Minjie, Cui, Bin, Gao, Yu-Tang, Go, Min Jin, Gu, Dongfeng, Gu, Weiqiong, Guo, Huan, Hao, Yongchen, Hong, Jie, Hu, Zhibin, Hu, Yanling, Huang, Jianfeng, Hwang, Joo-Yeon, Ikram, Mohammad Kamran, Jin, Guangfu, Kang, Dae-Hee, Khor, Chiea Chuen, Kim, Bong-Jo, Kim, Hung Tae, Kubo, Michiaki, Lee, Jeannette, Lee, Juyoung, Lee, Nanette R, Li, Ruoying, Li, Jun, Liu, JianJun, Longe, Jirong, Lu, Wei, Lu, Xiangfeng, Miao, Xiaoping, Okada, Yukinori, Ong, Rick Twee-Hee, Qiu, Gaokun, Seielstad, Mark, Sim, Xueling, Song, Huaidong, Takeuchi, Fumihiko, Tanaka, Toshihiro, Taylor, Phil R, Wang, Laiyuan, Wang, Weiqing, Wang, Yiqin, Wu, Chen, Wu, Ying, Xiang, Yong-Bing, Yamamoto, Ken, Yang, Handong, Liao, Ming, Yokota, Mitsuhiro, Young, Terri, Zhang, Xiaomin, Kato, Norihiro, Wang, Qing K, Zheng, Wei, Hu, Frank B, Lin, Dongxin, Shen, Hongbing, Teo, Yik Ying, Mo, Zengnan, Wong, Tien Yin, Lin, Xu, Mohlke, Karen L, Ning, Guang, Tsunoda, Tatsuhiko, Han, Bok-Ghee, Shu, Xiao-Ou, Tai, E Shyong, Wu, Tangchun, and Qi, Lu

Subjects
Prevention, Genetics, Human Genome, Aetiology, 2.1 Biological and endogenous factors, Adolescent, Adult, Aged, Aged, 80 and over, Asian People, Body Height, Asia, Eastern, Female, Gene Frequency, Genetic Loci, Genome-Wide Association Study, Humans, Male, Metabolic Networks and Pathways, Middle Aged, Polymorphism, Single Nucleotide, Protein Tyrosine Phosphatases, White People, Young Adult, Biological Sciences, Medical and Health Sciences, Genetics & Heredity
Abstract

Human height is associated with risk of multiple diseases and is profoundly determined by an individual's genetic makeup and shows a high degree of ethnic heterogeneity. Large-scale genome-wide association (GWA) analyses of adult height in Europeans have identified nearly 180 genetic loci. A recent study showed high replicability of results from Europeans-based GWA studies in Asians; however, population-specific loci may exist due to distinct linkage disequilibrium patterns. We carried out a GWA meta-analysis in 93 926 individuals from East Asia. We identified 98 loci, including 17 novel and 81 previously reported loci, associated with height at P < 5 × 10(-8), together explaining 8.89% of phenotypic variance. Among the newly identified variants, 10 are commonly distributed (minor allele frequency, MAF > 5%) in Europeans, with comparable frequencies with in Asians, and 7 single-nucleotide polymorphisms are with low frequency (MAF < 5%) in Europeans. In addition, our data suggest that novel biological pathway such as the protein tyrosine phosphatase family is involved in regulation of height. The findings from this study considerably expand our knowledge of the genetic architecture of human height in Asians.

Published
2015

9. Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index

Author

Wen, Wanqing, Zheng, Wei, Okada, Yukinori, Takeuchi, Fumihiko, Tabara, Yasuharu, Hwang, Joo-Yeon, Dorajoo, Rajkumar, Li, Huaixing, Tsai, Fuu-Jen, Yang, Xiaobo, He, Jiang, Wu, Ying, He, Meian, Zhang, Yi, Liang, Jun, Guo, Xiuqing, Sheu, Wayne Huey-Herng, Delahanty, Ryan, Guo, Xingyi, Kubo, Michiaki, Yamamoto, Ken, Ohkubo, Takayoshi, Go, Min Jin, Liu, Jian Jun, Gan, Wei, Chen, Ching-Chu, Gao, Yong, Li, Shengxu, Lee, Nanette R, Wu, Chen, Zhou, Xueya, Song, Huaidong, Yao, Jie, Lee, I-Te, Long, Jirong, Tsunoda, Tatsuhiko, Akiyama, Koichi, Takashima, Naoyuki, Cho, Yoon Shin, Ong, Rick TH, Lu, Ling, Chen, Chien-Hsiun, Tan, Aihua, Rice, Treva K, Adair, Linda S, Gui, Lixuan, Allison, Matthew, Lee, Wen-Jane, Cai, Qiuyin, Isomura, Minoru, Umemura, Satoshi, Kim, Young Jin, Seielstad, Mark, Hixson, James, Xiang, Yong-Bing, Isono, Masato, Kim, Bong-Jo, Sim, Xueling, Lu, Wei, Nabika, Toru, Lee, Juyoung, Lim, Wei-Yen, Gao, Yu-Tang, Takayanagi, Ryoichi, Kang, Dae-Hee, Wong, Tien Yin, Hsiung, Chao Agnes, Wu, I-Chien, Juang, Jyh-Ming Jimmy, Shi, Jiajun, Choi, Bo Youl, Aung, Tin, Hu, Frank, Kim, Mi Kyung, Lim, Wei Yen, Wang, Tzung-Dao, Shin, Min-Ho, Lee, Jeannette, Ji, Bu-Tian, Lee, Young-Hoon, Young, Terri L, Shin, Dong Hoon, Chun, Byung-Yeol, Cho, Myeong-Chan, Han, Bok-Ghee, Hwu, Chii-Min, Assimes, Themistocles L, Absher, Devin, Yan, Xiaofei, Kim, Eric, Kuo, Jane Z, Kwon, Soonil, Taylor, Kent D, Chen, Yii-Der I, Rotter, Jerome I, Qi, Lu, Zhu, Dingliang, Wu, Tangchun, Mohlke, Karen L, and Gu, Dongfeng

Subjects
Biological Sciences, Genetics, Obesity, Nutrition, Human Genome, Women's Health, 5'-Nucleotidase, Aldehyde Dehydrogenase, Aldehyde Dehydrogenase, Mitochondrial, Asian People, Blood Proteins, Body Mass Index, Cardiac Myosins, Asia, Eastern, Female, Genetic Predisposition to Disease, Genome-Wide Association Study, Glycoproteins, Humans, KCNQ1 Potassium Channel, Male, Myosin Light Chains, Polymorphism, Single Nucleotide, Proteinase Inhibitory Proteins, Secretory, Medical and Health Sciences, Genetics & Heredity
Abstract

Recent genetic association studies have identified 55 genetic loci associated with obesity or body mass index (BMI). The vast majority, 51 loci, however, were identified in European-ancestry populations. We conducted a meta-analysis of associations between BMI and ∼2.5 million genotyped or imputed single nucleotide polymorphisms among 86 757 individuals of Asian ancestry, followed by in silico and de novo replication among 7488-47 352 additional Asian-ancestry individuals. We identified four novel BMI-associated loci near the KCNQ1 (rs2237892, P = 9.29 × 10(-13)), ALDH2/MYL2 (rs671, P = 3.40 × 10(-11); rs12229654, P = 4.56 × 10(-9)), ITIH4 (rs2535633, P = 1.77 × 10(-10)) and NT5C2 (rs11191580, P = 3.83 × 10(-8)) genes. The association of BMI with rs2237892, rs671 and rs12229654 was significantly stronger among men than among women. Of the 51 BMI-associated loci initially identified in European-ancestry populations, we confirmed eight loci at the genome-wide significance level (P < 5.0 × 10(-8)) and an additional 14 at P < 1.0 × 10(-3) with the same direction of effect as reported previously. Findings from this analysis expand our knowledge of the genetic basis of obesity.

Published
2014

10. Systematic mining and functional analysis of factors regulating wheat spike development for breeding selection

Author

Xiao, Jun, primary, Lin, Xuelei, additional, Xu, Yongxin, additional, Wang, Dongzhi, additional, Yang, Yiman, additional, Zhang, Xiaoyu, additional, Bie, Xiao Min, additional, Wang, Hongzhe, additional, Jiang, Jiafu, additional, Chen, Zhongxu, additional, Gui, Lixuan, additional, Ding, Yiliang, additional, Che, Yuqing, additional, Li, Aili, additional, Zhang, Xueyong, additional, Lu, Fei, additional, Zhao, Xiang Yu, additional, Zhang, Xian Sheng, additional, and Fu, Xiangdong, additional

Published
2023
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11. Boosting wheat functional genomics via indexed EMS mutant library of KN9204

Author

Wang, Dongzhi, primary, Li, Yongpeng, additional, Wang, Haojie, additional, Xu, Yongxin, additional, Yang, Yiman, additional, Zhou, Yuxin, additional, Chen, Zhongxu, additional, Zhou, Yuqing, additional, Gui, Lixuan, additional, Guo, Yi, additional, Zhou, Chunjiang, additional, Tang, Wenqiang, additional, Zheng, Shuzhi, additional, Wang, Lei, additional, Guo, Xiulin, additional, Zhang, Yingjun, additional, Cui, Fa, additional, Lin, Xuelei, additional, Jiao, Yuling, additional, He, Yuehui, additional, Li, Junming, additional, He, Fei, additional, Liu, Xigang, additional, and Xiao, Jun, additional

Published
2022
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12. Systematic mining and functional analysis of factors regulating wheat spike development for breeding selection

Author

Lin, Xuelei, primary, Xu, Yongxin, additional, Wang, Dongzhi, additional, Yang, Yiman, additional, Zhang, Xiaoyu, additional, Bie, Xiaomin, additional, Wang, Hongzhe, additional, Jiang, Jiafu, additional, Chen, Zhongxu, additional, Gui, Lixuan, additional, Ding, Yiliang, additional, Che, Yuqing, additional, Li, Aili, additional, Zhang, Xueyong, additional, Lu, Fei, additional, Zhao, Xiangyu, additional, Zhang, Xiansheng, additional, Fu, Xiangdong, additional, and Xiao, Jun, additional

Published
2022
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14. A genome wide association study of genetic loci that influence tumour biomarkers cancer antigen 19-9, carcinoembryonic antigen and α fetoprotein and their associations with cancer risk

Author

He, Meian, Wu, Chen, Xu, Jianfeng, Guo, Huan, Yang, Handong, Zhang, Xiaomin, Sun, Jielin, Yu, Dianke, Zhou, Li, Peng, Tao, He, Yunfeng, Gao, Yong, Yuan, Jing, Deng, Qifei, Dai, Xiayun, Tan, Aihua, Feng, Yingying, Zhang, Haiying, Min, Xinwen, Yang, Xiaobo, Zhu, Jiang, Zhai, Kan, Chang, Jiang, Qin, Xue, Tan, Wen, Hu, Yanling, Lang, Mingjian, Tao, Sha, Li, Yuanfeng, Li, Yi, Feng, Junjie, Li, Dongfeng, Kim, Seong-Tae, Zhang, Shijun, Zhang, Hongxing, Zheng, S Lilly, Gui, Lixuan, Wang, Youjie, Wei, Sheng, Wang, Feng, Fang, Weimin, Liang, Yuan, Zhai, Yun, Chen, Weihong, Miao, Xiaoping, Zhou, Gangqiao, Hu, Frank B, Lin, Dongxin, Mo, Zengnan, and Wu, Tangchun

Published
2014
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15. Myb10‐D confers PHS‐3D resistance to pre‐harvest sprouting by regulating NCED in ABA biosynthesis pathway of wheat

Author

Lang, Jing, primary, Fu, Yuxin, additional, Zhou, Yong, additional, Cheng, Mengping, additional, Deng, Min, additional, Li, Maolian, additional, Zhu, Tingting, additional, Yang, Jian, additional, Guo, Xiaojiang, additional, Gui, Lixuan, additional, Li, Linchuan, additional, Chen, Zhongxu, additional, Yi, Yingjin, additional, Zhang, Lianquan, additional, Hao, Ming, additional, Huang, Lin, additional, Tan, Chao, additional, Chen, Guoyue, additional, Jiang, Qiantao, additional, Qi, Pengfei, additional, Pu, Zhien, additional, Ma, Jian, additional, Liu, Zehou, additional, Liu, Yujiao, additional, Luo, Ming‐Cheng, additional, Wei, Yuming, additional, Zheng, Youliang, additional, Wu, Yongrui, additional, Liu, Dengcai, additional, and Wang, JiRui, additional

Published
2021
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17. Combining a New Exome Capture Panel With an Effective varBScore Algorithm Accelerates BSA-Based Gene Cloning in Wheat

Author

Dong, Chunhao, primary, Zhang, Lichao, additional, Chen, Zhongxu, additional, Xia, Chuan, additional, Gu, Yongqiang, additional, Wang, Jirui, additional, Li, Danping, additional, Xie, Zhencheng, additional, Zhang, Qiang, additional, Zhang, Xueying, additional, Gui, Lixuan, additional, Liu, Xu, additional, and Kong, Xiuying, additional

Published
2020
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18. Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels

Author

Spracklen Cassandra N., Chen Peng, Kim Young Jin, Wang Xu, Cai Hui, Li Shengxu, Long Jirong, Wu Ying, Wang Ya Xing, Takeuchi Fumihiko, Wu Jer-Yuarn, Jung Keum-Ji, Hu Cheng, Akiyama Koichi, Zhang Yonghong, Moon Sanghoon, Johnson Todd A., Li Huaixing, Dorajoo Rajkumar, He Meian, Cannon Maren E., Roman Tamara S., Salfati Elias, Lin Keng-Hung, Guo Xiuqing, Sheu Wayne H. H., Absher Devin, Adair Linda S., Assimes Themistocles L., Aung Tin, Cai Qiuyin, Chang Li-Ching, Chen Chien-Hsiun, Chien Li-Hsin, Chuang Lee-Ming, Chuang Shu-Chun, Du Shufa, Fan Qiao, Fann Cathy S. J., Feranil Alan B., Friedlander Yechiel, Gordon-Larsen Penny, Gu Dongfeng, Gui Lixuan, Guo Zhirong, Heng Chew-Kiat, Hixson James, Hou Xuhong, Hsiung Chao Agnes, Hu Yao, Hwang Mi Yeong, Hwu Chii-Min, Isono Masato, Juang Jyh-Ming Jimmy, Khor Chiea-Chuen, Kim Yun Kyoung, Koh Woon-Puay, Kubo Michiaki, Lee I-Te, Lee Sun-Ju, Lee Wen-Jane, Liang Kae-Woei, Lim Blanche, Lim Sing-Hui, Liu Jianjun, Nabika, Toru, Pan Wen-Harn, Peng Hao, Quertermous Thomas, Sabanayagam Charumathi, Sandow Kevin, Shi Jinxiu, Sun Liang, Tan Pok Chien, Tan Shu-Pei, Taylor Kent D., Teo Yik-Ying, Toh Sue-Anne, Tsunoda Tatsuhiko, van Dam Rob M., Wang Aili, Wang Feijie, Wang Jie, Wei Wen Bin, Xiang Yong-Bing, Yao Jie, Yuan Jian-Min, Zhang Rong, Zhao Wanting, Chen Yii-Der Ida, Rich Stephen S., Rotter Jerome I., Wang Tzung-Dau, Wu Tangchun, Lin Xu, Han Bok-Ghee, Tanaka Toshihiro, Cho Yoon Shin, Katsuya Tomohiro, Jia Weiping, Jee Sun-Ha, Chen Yuan-Tsong, Kato Norihiro, Jonas Jost B., Cheng Ching-Yu, Shu Xiao-Ou, He Jiang, Zheng Wei, Wong Tien-Yin, Huang Wei, Kim Bong-Jo, Tai E-Shyong, Mohlke Karen L., Sim Xueling, Spracklen Cassandra N., Chen Peng, Kim Young Jin, Wang Xu, Cai Hui, Li Shengxu, Long Jirong, Wu Ying, Wang Ya Xing, Takeuchi Fumihiko, Wu Jer-Yuarn, Jung Keum-Ji, Hu Cheng, Akiyama Koichi, Zhang Yonghong, Moon Sanghoon, Johnson Todd A., Li Huaixing, Dorajoo Rajkumar, He Meian, Cannon Maren E., Roman Tamara S., Salfati Elias, Lin Keng-Hung, Guo Xiuqing, Sheu Wayne H. H., Absher Devin, Adair Linda S., Assimes Themistocles L., Aung Tin, Cai Qiuyin, Chang Li-Ching, Chen Chien-Hsiun, Chien Li-Hsin, Chuang Lee-Ming, Chuang Shu-Chun, Du Shufa, Fan Qiao, Fann Cathy S. J., Feranil Alan B., Friedlander Yechiel, Gordon-Larsen Penny, Gu Dongfeng, Gui Lixuan, Guo Zhirong, Heng Chew-Kiat, Hixson James, Hou Xuhong, Hsiung Chao Agnes, Hu Yao, Hwang Mi Yeong, Hwu Chii-Min, Isono Masato, Juang Jyh-Ming Jimmy, Khor Chiea-Chuen, Kim Yun Kyoung, Koh Woon-Puay, Kubo Michiaki, Lee I-Te, Lee Sun-Ju, Lee Wen-Jane, Liang Kae-Woei, Lim Blanche, Lim Sing-Hui, Liu Jianjun, Nabika, Toru, Pan Wen-Harn, Peng Hao, Quertermous Thomas, Sabanayagam Charumathi, Sandow Kevin, Shi Jinxiu, Sun Liang, Tan Pok Chien, Tan Shu-Pei, Taylor Kent D., Teo Yik-Ying, Toh Sue-Anne, Tsunoda Tatsuhiko, van Dam Rob M., Wang Aili, Wang Feijie, Wang Jie, Wei Wen Bin, Xiang Yong-Bing, Yao Jie, Yuan Jian-Min, Zhang Rong, Zhao Wanting, Chen Yii-Der Ida, Rich Stephen S., Rotter Jerome I., Wang Tzung-Dau, Wu Tangchun, Lin Xu, Han Bok-Ghee, Tanaka Toshihiro, Cho Yoon Shin, Katsuya Tomohiro, Jia Weiping, Jee Sun-Ha, Chen Yuan-Tsong, Kato Norihiro, Jonas Jost B., Cheng Ching-Yu, Shu Xiao-Ou, He Jiang, Zheng Wei, Wong Tien-Yin, Huang Wei, Kim Bong-Jo, Tai E-Shyong, Mohlke Karen L., and Sim Xueling

Published
2017

19. Genome-Wide Association Study Meta-Analysis of Long-Term Average Blood Pressure in East Asians

Author

Li, Changwei, primary, Kim, Yun Kyoung, additional, Dorajoo, Rajkumar, additional, Li, Huaixing, additional, Lee, I-Te, additional, Cheng, Ching-Yu, additional, He, Meian, additional, Sheu, Wayne H-h, additional, Guo, Xiuqing, additional, Ganesh, Santhi K., additional, He, Jiang, additional, Lee, Juyoung, additional, Liu, Jianjun, additional, Hu, Yao, additional, Rao, Dabeeru C., additional, Tsai, Fuu-Jen, additional, Koh, Jia Yu, additional, Hu, Hua, additional, Liang, Kae-Woei, additional, Palmas, Walter, additional, Hixson, James E., additional, Han, Sohee, additional, Teo, Yik-Ying, additional, Wang, Yiqin, additional, Chen, Jing, additional, Lu, Chieh Hsiang, additional, Zheng, Yingfeng, additional, Gui, Lixuan, additional, Lee, Wen-Jane, additional, Yao, Jie, additional, Gu, Dongfeng, additional, Han, Bok-Ghee, additional, Sim, Xueling, additional, Sun, Liang, additional, Zhao, Jinying, additional, Chen, Chien-Hsiun, additional, Kumari, Neelam, additional, He, Yunfeng, additional, Taylor, Kent D., additional, Raffel, Leslie J., additional, Moon, Sanghoon, additional, Rotter, Jerome I., additional, Ida Chen, Yii-der, additional, Wu, Tangchun, additional, Wong, Tien Yin, additional, Wu, Jer-Yuarn, additional, Lin, Xu, additional, Tai, E-Shyong, additional, Kim, Bong-Jo, additional, and Kelly, Tanika N., additional

Published
2017
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21. Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index

Author

Wen Wanqing, Zheng Wei, Okada Yukinori, Takeuchi Fumihiko, Tabara Yasuharu, Hwang Joo-Yeon, Dorajoo Rajkumar, Li Huaixing, Tsai Fuu-Jen, Yang Xiaobo, He Jiang, Wu Ying, He Meian, Zhang Yi, Liang Jun, Guo Xiuqing, Sheu Wayne Huey-Herng, Delahanty Ryan, Guo Xingyi, Kubo Michiaki, Yamamoto Ken, Ohkubo Takayoshi, Go Min Jin, Liu Jian Jun, Gan Wei, Chen Ching-Chu, Gao Yong, Li Shengxu, Lee Nanette R., Wu Chen, Zhou Xueya, Song Huaidong, Yao Jie, Lee I-Te, Long Jirong, Tsunoda Tatsuhiko, Akiyama Koichi, Takashima Naoyuki, Cho Yoon Shin, Ong Rick T. H., Lu Ling, Chen Chien-Hsiun, Tan Aihua, Rice Treva K., Adair Linda S., Gui Lixuan, Allison Matthew, Lee Wen-Jane, Cai Qiuyin, ISOMURA, Minoru, Umemura Satoshi, Kim Young Jin, Seielstad Mark, Hixson James, Xiang Yong-Bing, Isono Masato, Kim Bong-Jo, Sim Xueling, Lu Wei, Nabika, Toru, Lee Juyoung, Lim Wei-Yen, Gao Yu-Tang, Takayanagi Ryoichi, Kang Dae-Hee, Wong Tien Yin, Hsiung ChaoAgnes, Wu I-Chien, Juang Jyh-Ming Jimmy, Shi Jiajun, Choi Bo Youl, Aung Tin, Hu Frank, Kim Mi Kyung, Lim WeiYen, Wang Tzung-Dao, Shin Min-Ho, Lee Jeannette, Ji Bu-Tian, Lee Young-Hoon, Young Terri L., Shin Dong Hoon, Chun Byung-Yeol, Cho Myeong-Chan, Han Bok-Ghee, Hwu Chii-Min, Assimes Themistocles L., Absher Devin, Yan Xiaofei, Kim Eric, Kuo Jane Z., Kwon Soonil, Taylor Kent D., Chen Yii-Der I., Rotter Jerome I., Qi Lu, Zhu Dingliang, Wu Tangchun, Mohlke Karen L., Gu Dongfeng, Mo Zengnan, Wu Jer-Yuarn, Lin Xu, Miki Tetsuro, Tai E. Shyong, Lee Jong-Young, Kato Norihiro, Shu Xiao-Ou, Tanaka Toshihiro, Wen Wanqing, Zheng Wei, Okada Yukinori, Takeuchi Fumihiko, Tabara Yasuharu, Hwang Joo-Yeon, Dorajoo Rajkumar, Li Huaixing, Tsai Fuu-Jen, Yang Xiaobo, He Jiang, Wu Ying, He Meian, Zhang Yi, Liang Jun, Guo Xiuqing, Sheu Wayne Huey-Herng, Delahanty Ryan, Guo Xingyi, Kubo Michiaki, Yamamoto Ken, Ohkubo Takayoshi, Go Min Jin, Liu Jian Jun, Gan Wei, Chen Ching-Chu, Gao Yong, Li Shengxu, Lee Nanette R., Wu Chen, Zhou Xueya, Song Huaidong, Yao Jie, Lee I-Te, Long Jirong, Tsunoda Tatsuhiko, Akiyama Koichi, Takashima Naoyuki, Cho Yoon Shin, Ong Rick T. H., Lu Ling, Chen Chien-Hsiun, Tan Aihua, Rice Treva K., Adair Linda S., Gui Lixuan, Allison Matthew, Lee Wen-Jane, Cai Qiuyin, ISOMURA, Minoru, Umemura Satoshi, Kim Young Jin, Seielstad Mark, Hixson James, Xiang Yong-Bing, Isono Masato, Kim Bong-Jo, Sim Xueling, Lu Wei, Nabika, Toru, Lee Juyoung, Lim Wei-Yen, Gao Yu-Tang, Takayanagi Ryoichi, Kang Dae-Hee, Wong Tien Yin, Hsiung ChaoAgnes, Wu I-Chien, Juang Jyh-Ming Jimmy, Shi Jiajun, Choi Bo Youl, Aung Tin, Hu Frank, Kim Mi Kyung, Lim WeiYen, Wang Tzung-Dao, Shin Min-Ho, Lee Jeannette, Ji Bu-Tian, Lee Young-Hoon, Young Terri L., Shin Dong Hoon, Chun Byung-Yeol, Cho Myeong-Chan, Han Bok-Ghee, Hwu Chii-Min, Assimes Themistocles L., Absher Devin, Yan Xiaofei, Kim Eric, Kuo Jane Z., Kwon Soonil, Taylor Kent D., Chen Yii-Der I., Rotter Jerome I., Qi Lu, Zhu Dingliang, Wu Tangchun, Mohlke Karen L., Gu Dongfeng, Mo Zengnan, Wu Jer-Yuarn, Lin Xu, Miki Tetsuro, Tai E. Shyong, Lee Jong-Young, Kato Norihiro, Shu Xiao-Ou, and Tanaka Toshihiro

Published
2014

23. Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci

Author

He, Meian, primary, Xu, Min, additional, Zhang, Ben, additional, Liang, Jun, additional, Chen, Peng, additional, Lee, Jong-Young, additional, Johnson, Todd A., additional, Li, Huaixing, additional, Yang, Xiaobo, additional, Dai, Juncheng, additional, Liang, Liming, additional, Gui, Lixuan, additional, Qi, Qibin, additional, Huang, Jinyan, additional, Li, Yanping, additional, Adair, Linda S., additional, Aung, Tin, additional, Cai, Qiuyin, additional, Cheng, Ching-Yu, additional, Cho, Myeong-Chan, additional, Cho, Yoon Shin, additional, Chu, Minjie, additional, Cui, Bin, additional, Gao, Yu-Tang, additional, Go, Min Jin, additional, Gu, Dongfeng, additional, Gu, Weiqiong, additional, Guo, Huan, additional, Hao, Yongchen, additional, Hong, Jie, additional, Hu, Zhibin, additional, Hu, Yanling, additional, Huang, Jianfeng, additional, Hwang, Joo-Yeon, additional, Ikram, Mohammad Kamran, additional, Jin, Guangfu, additional, Kang, Dae-Hee, additional, Khor, Chiea Chuen, additional, Kim, Bong-Jo, additional, Kim, Hung Tae, additional, Kubo, Michiaki, additional, Lee, Jeannette, additional, Lee, Juyoung, additional, Lee, Nanette R., additional, Li, Ruoying, additional, Li, Jun, additional, Liu, JianJun, additional, Longe, Jirong, additional, Lu, Wei, additional, Lu, Xiangfeng, additional, Miao, Xiaoping, additional, Okada, Yukinori, additional, Ong, Rick Twee-Hee, additional, Qiu, Gaokun, additional, Seielstad, Mark, additional, Sim, Xueling, additional, Song, Huaidong, additional, Takeuchi, Fumihiko, additional, Tanaka, Toshihiro, additional, Taylor, Phil R., additional, Wang, Laiyuan, additional, Wang, Weiqing, additional, Wang, Yiqin, additional, Wu, Chen, additional, Wu, Ying, additional, Xiang, Yong-Bing, additional, Yamamoto, Ken, additional, Yang, Handong, additional, Liao, Ming, additional, Yokota, Mitsuhiro, additional, Young, Terri, additional, Zhang, Xiaomin, additional, Kato, Norihiro, additional, Wang, Qing K., additional, Zheng, Wei, additional, Hu, Frank B., additional, Lin, Dongxin, additional, Shen, Hongbing, additional, Teo, Yik Ying, additional, Mo, Zengnan, additional, Wong, Tien Yin, additional, Lin, Xu, additional, Mohlke, Karen L., additional, Ning, Guang, additional, Tsunoda, Tatsuhiko, additional, Han, Bok-Ghee, additional, Shu, Xiao-Ou, additional, Tai, E. Shyong, additional, Wu, Tangchun, additional, and Qi, Lu, additional

Published
2014
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24. A genome-wide association study identifies common variants influencing serum uric acid concentrations in a Chinese population

Author

Yang, Binyao, primary, Mo, Zengnan, additional, Wu, Chen, additional, Yang, Handong, additional, Yang, Xiaobo, additional, He, Yunfeng, additional, Gui, Lixuan, additional, Zhou, Li, additional, Guo, Huan, additional, Zhang, Xiaomin, additional, Yuan, Jing, additional, Dai, Xiayun, additional, Li, Jun, additional, Qiu, Gaokun, additional, Huang, Suli, additional, Deng, Qifei, additional, Feng, Yingying, additional, Guan, Lei, additional, Hu, Die, additional, Zhang, Xiao, additional, Wang, Tian, additional, Zhu, Jiang, additional, Min, Xinwen, additional, Lang, Mingjian, additional, Li, Dongfeng, additional, Hu, Frank B, additional, Lin, Dongxin, additional, Wu, Tangchun, additional, and He, Meian, additional

Published
2014
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25. Genome-wide association study on serum alkaline phosphatase levels in a Chinese population

Author

Li, Jun, primary, Gui, Lixuan, additional, Wu, Chen, additional, He, Yunfeng, additional, Zhou, Li, additional, Guo, Huan, additional, Yuan, Jing, additional, Yang, Binyao, additional, Dai, Xiayun, additional, Deng, Qifei, additional, Huang, Suli, additional, Guan, Lei, additional, Hu, Die, additional, Deng, Siyun, additional, Wang, Tian, additional, Zhu, Jiang, additional, Min, Xinwen, additional, Lang, Mingjian, additional, Li, Dongfeng, additional, Yang, Handong, additional, Hu, Frank B, additional, Lin, Dongxin, additional, Wu, Tangchun, additional, and He, Meian, additional

Published
2013
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26. A Genome‐Wide Association Study for Serum Bilirubin Levels and Gene‐Environment Interaction in a Chinese Population

Author

Dai, Xiayun, primary, Wu, Chen, additional, He, Yunfeng, additional, Gui, Lixuan, additional, Zhou, Li, additional, Guo, Huan, additional, Yuan, Jing, additional, Yang, Binyao, additional, Li, Jun, additional, Deng, Qifei, additional, Huang, Suli, additional, Guan, Lei, additional, Hu, Die, additional, Zhu, Jiang, additional, Min, Xinwen, additional, Lang, Mingjian, additional, Li, Dongfeng, additional, Yang, Handong, additional, Hu, Frank B., additional, Lin, Dongxin, additional, Wu, Tangchun, additional, and He, Meian, additional

Published
2013
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27. A genome wide association study of genetic loci that influence tumour biomarkers cancer antigen 19-9, carcinoembryonic antigen and α fetoprotein and their associations with cancer risk

Author

He, Meian, primary, Wu, Chen, additional, Xu, Jianfeng, additional, Guo, Huan, additional, Yang, Handong, additional, Zhang, Xiaomin, additional, Sun, Jielin, additional, Yu, Dianke, additional, Zhou, Li, additional, Peng, Tao, additional, He, Yunfeng, additional, Gao, Yong, additional, Yuan, Jing, additional, Deng, Qifei, additional, Dai, Xiayun, additional, Tan, Aihua, additional, Feng, Yingying, additional, Zhang, Haiying, additional, Min, Xinwen, additional, Yang, Xiaobo, additional, Zhu, Jiang, additional, Zhai, Kan, additional, Chang, Jiang, additional, Qin, Xue, additional, Tan, Wen, additional, Hu, Yanling, additional, Lang, Mingjian, additional, Tao, Sha, additional, Li, Yuanfeng, additional, Li, Yi, additional, Feng, Junjie, additional, Li, Dongfeng, additional, Kim, Seong-Tae, additional, Zhang, Shijun, additional, Zhang, Hongxing, additional, Zheng, S Lilly, additional, Gui, Lixuan, additional, Wang, Youjie, additional, Wei, Sheng, additional, Wang, Feng, additional, Fang, Weimin, additional, Liang, Yuan, additional, Zhai, Yun, additional, Chen, Weihong, additional, Miao, Xiaoping, additional, Zhou, Gangqiao, additional, Hu, Frank B, additional, Lin, Dongxin, additional, Mo, Zengnan, additional, and Wu, Tangchun, additional

Published
2013
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