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16 results on '"Guglielmelli, V"'

3. La PGEI nel trattamento del piede diabetico

Author

PASSARIELLO, Nicola, Di Monda G, Mancone M, Guglielmelli V, Ruotolo U, Santorelli A, Sgambato S., Passariello, Nicola, Di Monda, G, Mancone, M, Guglielmelli, V, Ruotolo, U, Santorelli, A, and Sgambato, S.

Published
1996

4. [Treatment of chronic hepatitis C with lymphoblastic interferon. Long-term follow-up]

Author

PASSARIELLO, Nicola, Sepe J, Peluso A, Carlino F, Guglielmelli V, Esposito P, ROSSIELLO, Raffaele, d'Onofrio F, Sgambato S., Passariello, Nicola, Sepe, J, Peluso, A, Carlino, F, Guglielmelli, V, Esposito, P, Rossiello, Raffaele, D'Onofrio, F, and Sgambato, S.

Subjects
Adult, Male, Time Factors, Interferon-alpha, Alanine Transaminase, Middle Aged, Antiviral Agents, Hepatitis C, Double-Blind Method, Liver, Chronic Disease, Humans, Female, Follow-Up Studies
Abstract

A randomized controlled trial was set up to assess the effect of two different therapy regimens with lymphoblastoid interferon on the treatment and follow-up of patients with chronic C hepatitis.Eighty-five patients with chronic hepatitis C were randomized into two treatment groups (n = 30 respectively) and one control group (no treatment: n = 25). In one treatment group patients received three million units of alpha-lymphoblastoid interferon. The other received six million units.A rapid decline in both alanine aminotransferase and aspartataminotransferase levels was seen in most treated patients (a complete response in 51% from group A and 55% from group B; partial response 29% from group A, 25% from group B). In five partial responders and six complete responders from group A and in seven partial responders and six complete responders in group B serum aminotransferase levels returned to baseline values in the follow-up. No change in serum bilirubin, albumin, IgG and prothrombin time during interferon treatment were seen. The histologic staging remained unchanged throughout the entire study.alpha-interferon treatment improves the clinical picture, biochemical parameters and histologic pattern in a large percentage of patients with hepatitis C. Long-term remission was seen in only 37% of treated patients. Using six million units of alpha-interferon has not proven to be significantly better than three million units. Protracted treatment for nine months seems to increase the percentage of patients in biochemical and histologic remission.

Published
1995

12. La retinopatia diabetica nel diabete tipo I. Studio trasversale

Author

PASSARIELLO, Nicola, Sgambato S, Guglielmelli V, Marrazzo G, Peluso A, Vignoli A, Lapiello B. Sepe J, Pisano MCA, Passariello, Nicola, Sgambato, S, Guglielmelli, V, Marrazzo, G, Peluso, A, Vignoli, A, Lapiello B., Sepe J, and Pisano, Mca

Published
1993

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