590 results on '"Guessous, I."'
Search Results
2. French-speaking Swiss physician’s perceptions and perspectives regarding their competencies and training need in leadership and management: a mixed-methods study
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Lüchinger, R., Audétat, M-C., Bajwa, N. M., Bréchet-Bachmann, A-C., Guessous, I., Richard-Lepouriel, H., Dominicé Dao, M., and Perron, Junod
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- 2023
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3. Acute TNFα levels predict cognitive impairment 6–9 months after COVID-19 infection
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Nuber-Champier, A., Cionca, A., Breville, G., Voruz, P., de Alcântara, I. Jacot, Allali, G., Lalive, P.H., Benzakour, L., Lövblad, K.-O., Braillard, O., Nehme, M., Coen, M., Serratrice, J., Reny, J.-L., Pugin, J., Guessous, I., Landis, B.N., Griffa, A., De Ville, D. Van, Assal, F., and Péron, J.A.
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- 2023
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4. Validation of a commercially available SARS-CoV-2 serological immunoassay
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Meyer, B., Torriani, G., Yerly, S., Mazza, L., Calame, A., Arm-Vernez, I., Zimmer, G., Agoritsas, T., Stirnemann, J., Spechbach, H., Guessous, I., Stringhini, S., Pugin, J., Roux-Lombard, P., Fontao, L., Siegrist, C.-A., Eckerle, I., Vuilleumier, N., and Kaiser, L.
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- 2020
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5. No association between vitamin d levels and all-cause or cardiovascular mortality. Prospective, population-based study.
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Patriota, P., primary, Maung, K.K., additional, Guessous, I., additional, Rezzi, S., additional, and Marques-Vidal, P., additional
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- 2023
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6. Prevalence of fatigue in the general population during the pandemic: cross-sectional study in Geneva
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Graindorge, C, primary, Baysson, H, additional, Pullen, N, additional, Schrempft, S, additional, Zaballa, M E, additional, Stringhini, S, additional, and Guessous, I, additional
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- 2023
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7. Nutrition and food supply after the Covid-19 pandemic: results from the Specchio cohort study
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Baysson, H, primary, Pullen, N, additional, Lamour, J, additional, Zaballa, M, additional, Guessous, I, additional, and Stringhini, S, additional
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- 2023
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8. Corrigendum to “Acute TNFα levels predict cognitive impairment 6–9 months after COVID-19 infection” [Psychoneuroendocrinology 153 (2023) 106104]
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Nuber-Champier, A., primary, Cionca, A., additional, Breville, G., additional, Voruz, P., additional, Jacot de Alcântara, I., additional, Allali, G., additional, Lalive, P.H., additional, Benzakour, L., additional, Lövblad, K.-O., additional, Braillard, O., additional, Nehme, M., additional, Coen, M., additional, Serratrice, J., additional, Reny, J.-L., additional, Pugin, J., additional, Guessous, I., additional, Landis, B.N., additional, Griffa, A., additional, Van De Ville, D., additional, Assal, F., additional, and Péron, J.A., additional
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- 2023
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9. Spatial analysis of 10-year predicted risk and incident cardiovascular atherosclerotic diseases in a swiss urban population
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Jordan, G, primary, Ridder, D, additional, Guessous, I, additional, Joost, S, additional, Vollenweider, P, additional, Marques-Vidal, P, additional, and Vaucher, J, additional
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- 2023
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10. Association between anthropometric markers of adiposity, adipokines and vitamin d levels.
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Patriota, P., primary, Rezzi, S., additional, Guessous, I., additional, and Vidal, P. Marques, additional
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- 2023
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11. Worldwide trends in diabetes since 1980: a pooled analysis of 751 population-based studies with 4·4 million participants
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Zhou, B, Lu, Y, Hajifathalian, K, Bentham, J, Di Cesare, M, Danaei, G, Bixby, H, Cowan, MJ, Ali, MK, Taddei, C, Lo, WC, Reis-Santos, B, Stevens, GA, Riley, LM, Miranda, JJ, Bjerregaard, P, Rivera, JA, Fouad, HM, Ma, G, Mbanya, JC, McGarvey, ST, Mohan, V, Onat, A, Pilav, A, Ramachandran, A, Romdhane, HB, Paciorek, CJ, Bennett, JE, Ezzati, M, Abdeen, ZA, Abdul Kadir, K, Abu-Rmeileh, NM, Acosta-Cazares, B, Adams, R, Aekplakorn, W, Aguilar-Salinas, CA, Agyemang, C, Ahmadvand, A, Al-Othman, AR, Alkerwi, A, Amouyel, P, Amuzu, A, Andersen, LB, Anderssen, SA, Anjana, RM, Aounallah-Skhiri, H, Aris, T, Arlappa, N, Arveiler, D, Assah, FK, Avdicová, M, Azizi, F, Balakrishna, N, Bandosz, P, Barbagallo, CM, Barceló, A, Batieha, AM, Baur, LA, Benet, M, Bernabe-Ortiz, A, Bharadwaj, S, Bhargava, SK, Bi, Y, Bjertness, E, Bjertness, MB, Björkelund, C, Blokstra, A, Bo, S, Boehm, BO, Boissonnet, CP, Bovet, P, Brajkovich, I, Breckenkamp, J, Brenner, H, Brewster, LM, Brian, GR, Bruno, G, Bugge, A, Cabrera de León, A, Can, G, Cândido, AP, Capuano, V, Carlsson, AC, Carvalho, MJ, Casanueva, FF, Casas, JP, Caserta, CA, Castetbon, K, Chamukuttan, S, Chaturvedi, N, Chen, CJ, Chen, F, Chen, S, Cheng, CY, Chetrit, A, Chiou, ST, Cho, Y, Chudek, J, Cifkova, R, Claessens, F, Concin, H, Cooper, C, Cooper, R, Costanzo, S, Cottel, D, Cowell, C, Crujeiras, AB, D'Arrigo, G, Dallongeville, J, Dankner, R, Dauchet, L, de Gaetano, G, De Henauw, S, Deepa, M, Dehghan, A, Deschamps, V, Dhana, K, Di Castelnuovo, AF, Djalalinia, S, Doua, K, Drygas, W, Du, Y, Dzerve, V, Egbagbe, EE, Eggertsen, R, El Ati, J, Elosua, R, Erasmus, RT, Erem, C, Ergor, G, Eriksen, L, Escobedo-de la Peña, J, Fall, CH, Farzadfar, F, Felix-Redondo, FJ, Ferguson, TS, Fernández-Bergés, D, Ferrari, M, Ferreccio, C, Feskens, EJ, Finn, JD, Föger, B, Foo, LH, Forslund, AS, Francis, DK, Franco Mdo, C, Franco, OH, Frontera, G, Furusawa, T, Gaciong, Z, Garnett, SP, Gaspoz, JM, Gasull, M, Gates, L, Geleijnse, JM, Ghasemian, A, Ghimire, A, Giampaoli, S, Gianfagna, F, Giovannelli, J, Giwercman, A, Gross, MG, González Rivas, JP, Gorbea, MB, Gottrand, F, Grafnetter, D, Grodzicki, T, Grøntved, A, Gruden, G, Gu, D, Guan, OP, Guerrero, R, Guessous, I, Guimaraes, AL, Gutierrez, L, Hambleton, IR, Hardy, R, Hari Kumar, R, Hata, J, He, J, Heidemann, C, Herrala, S, Hihtaniemi, IT, Ho, SY, Ho, SC, Hofman, A, Hormiga, CM, Horta, BL, Houti, L, Howitt, C, Htay, TT, Htet, AS, Htike, MM, Hu, Y, Hussieni, AS, Huybrechts, I, Hwalla, N, Iacoviello, L, Iannone, AG, Ibrahim, MM, Ikeda, N, Ikram, MA, Irazola, VE, Islam, M, Iwasaki, M, Jacobs, JM, Jafar, T, Jamil, KM, Jasienska, G, Jiang, CQ, Jonas, JB, Joshi, P, Kafatos, A, Kalter-Leibovici, O, Kasaeian, A, Katz, J, Kaur, P, Kavousi, M, Keinänen-Kiukaanniemi, S, Kelishadi, R, Kengne, AP, Kersting, M, Khader, YS, Khalili, D, Khang, YH, Kiechl, S, Kim, J, Kolsteren, P, Korrovits, P, Kratzer, W, Kromhout, D, Kujala, UM, Kula, K, Kyobutungi, C, Laatikainen, T, Lachat, C, Laid, Y, Lam, TH, Landrove, O, Lanska, V, Lappas, G, Laxmaiah, A, Leclercq, C, Lee, J, Lehtimäki, T, Lekhraj, R, León-Muñoz, LM, Li, Y, Lim, WY, Lima-Costa, MF, Lin, HH, Lin, X, Lissner, L, Lorbeer, R, Lozano, JE, Luksiene, D, Lundqvist, A, Lytsy, P, Machado-Coelho, GL, Machi, S, Maggi, S, Magliano, DJ, Makdisse, M, Mallikharjuna Rao, K, Manios, Y, Manzato, E, Margozzini, P, Marques-Vidal, P, Martorell, R, Masoodi, SR, Mathiesen, EB, Matsha, TE, McFarlane, SR, McLachlan, S, McNulty, BA, Mediene-Benchekor, S, Meirhaeghe, A, Menezes, AM, Merat, S, Meshram, II, Mi, J, Miquel, JF, Mohamed, MK, Mohammad, K, Mohammadifard, N, Mohd Yusoff, MF, Møller, NC, Molnár, D, Mondo, CK, Morejon, A, Moreno, LA, Morgan, K, Moschonis, G, Mossakowska, M, Mostafa, A, Mota, J, Motta, J, Mu, TT, Muiesan, ML, Müller-Nurasyid, M, Mursu, J, Nagel, G, Námešná, J, Nang, EE, NangThetia, VB, Navarrete-Muñoz, EM, Ndiaye, NC, Nenko, I, Nervi, F, Nguyen, ND, Nguyen, QN, Nieto-Martínez, RE, Ning, G, Ninomiya, T, Noale, M, Noto, D, Nsour, MA, Ochoa-Avilés, AM, Oh, K, Ordunez, P, Osmond, C, Otero, JA, Owusu-Dabo, E, Pahomova, E, Palmieri, L, Panda-Jonas, S, Panza, F, Parsaeian, M, Peixoto, SV, Pelletier, C, Peltonen, M, Peters, A, Peykari, N, Pham, ST, Pitakaka, F, Piwonska, A, Piwonski, J, Plans-Rubió, P, Porta, M, Portegies, ML, Poustchi, H, Pradeepa, R, Price, JF, Punab, M, Qasrawi, RF, Qorbani, M, Radisauskas, R, Rahman, M, Raitakari, O, Rao, SR, Ramke, J, Ramos, R, Rampal, S, Rathmann, W, Redon, J, Reganit, PF, Rigo, F, Robinson, SM, Robitaille, C, Rodríguez-Artalejo, F, Rodriguez-Perez Mdel, C, Rodríguez-Villamizar, LA, Rojas-Martinez, R, Ronkainen, K, Rosengren, A, Rubinstein, A, Rui, O, Ruiz-Betancourt, BS, Russo Horimoto, RV, Rutkowski, M, Sabanayagam, C, Sachdev, HS, Saidi, O, Sakarya, S, Salanave, B, Salonen, JT, Salvetti, M, Sánchez-Abanto, J, Santos, D, dos Santos, RN, Santos, R, Saramies, JL, Sardinha, LB, Sarrafzadegan, N, Saum, KU, Scazufca, M, Schargrodsky, H, Scheidt-Nave, C, Sein, AA, Sharma, SK, Shaw, JE, Shibuya, K, Shin, Y, Shiri, R, Siantar, R, Sibai, AM, Simon, M, Simons, J, Simons, LA, Sjostrom, M, Slowikowska-Hilczer, J, Slusarczyk, P, Smeeth, L, Snijder, MB, So, HK, Sobngwi, E, Söderberg, S, Solfrizzi, V, Sonestedt, E, Soumare, A, Staessen, JA, Stathopoulou, MG, Steene-Johannessen, J, Stehle, P, Stein, AD, Stessman, J, Stöckl, D, Stokwiszewski, J, Stronks, K, Strufaldi, MW, Sun, CA, Sundström, J, Sung, YT, Suriyawongpaisal, P, Sy, RG, Tai, ES, Tamosiunas, A, Tang, L, Tarawneh, M, Tarqui-Mamani, CB, Taylor, A, Theobald, H, Thijs, L, Thuesen, BH, Tolonen, HK, Tolstrup, JS, Topbas, M, Torrent, M, Traissac, P, Trinh, OT, Tulloch-Reid, MK, Tuomainen, TP, Turley, ML, Tzourio, C, Ueda, P, Ukoli, FA, Ulmer, H, Uusitalo, HM, Valdivia, G, Valvi, D, van Rossem, L, van Valkengoed, IG, Vanderschueren, D, Vanuzzo, D, Vega, T, Velasquez-Melendez, G, Veronesi, G, Verschuren, WM, Verstraeten, R, Viet, L, Vioque, J, Virtanen, JK, Visvikis-Siest, S, Viswanathan, B, Vollenweider, P, Voutilainen, S, Vrijheid, M, Wade, AN, Wagner, A, Walton, J, Wan Mohamud, WN, Wang, F, Wang, MD, Wang, Q, Wang, YX, Wannamethee, SG, Weerasekera, D, Whincup, PH, Widhalm, K, Wiecek, A, Wijga, AH, Wilks, RJ, Willeit, J, Wilsgaard, T, Wojtyniak, B, Wong, TY, Woo, J, Woodward, M, Wu, FC, Wu, SL, Xu, H, Yan, W, Yang, X, Ye, X, Yoshihara, A, Younger-Coleman, NO, Zambon, S, Zargar, AH, Zdrojewski, T, Zhao, W, Zheng, Y, and Zuñiga Cisneros, J
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- 2016
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12. IMPACT OF THE INTRODUCTION OF MAMMOGRAPHY PROGRAMMES ON SOCIOECONOMIC INEQUALITIES IN BREAST CANCER SCREENING IN SWITZERLAND
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Cullati, S, Courvoisier, DS, Burton-Jeangros, C, Manor, O, Bouchardy, C, and Guessous, I
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- 2016
13. Effects of diabetes definition on global surveillance of diabetes prevalence and diagnosis: a pooled analysis of 96 population-based studies with 331 288 participants
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Danaei, G, Fahimi, S, Lu, Y, Zhou, B, Hajifathalian, K, Di Cesare, M, Lo, WC, Reis-Santos, B, Cowan, MJ, Shaw, JE, Bentham, J, Lin, JK, Bixby, H, Magliano, D, Bovet, P, Miranda, JJ, Khang, YH, Stevens, GA, Riley, LM, Ali, MK, Ezzati, M, Abdeen, ZA, Kadir, KA, Abu-Rmeileh, M, Acosta-Cazares, B, Aekplakorn, W, Aguilar-Salinas, CA, Ahmadvand, A, Al Nsour, M, Alkerwi, A, Amouyel, P, Andersen, LB, Anderssen, SA, Andrade, DS, Anjana, RM, Aounallah-Skhiri, H, Aris, T, Arlappa, N, Arveiler, D, Assah, FK, Avdicová, M, Balakrishna, N, Bandosz, P, Barbagallo, CM, Barceló, A, Batieha, AM, Baur, LA, Ben Romdhane, H, Bernabe-Ortiz, A, Bhargava, SK, Bi, Y, Bjerregaard, P, Björkelund, C, Blake, M, Blokstra, A, Bo, S, Boehm, BO, Boissonnet, CP, Brajkovich, I, Breckenkamp, J, Brewster, LM, Brian, GR, Bruno, G, Bugge, A, Cabrera de León, A, Can, G, Cândido, AP, Capuano, V, Carvalho, MJ, Casanueva, FF, Caserta, CA, Castetbon, K, Chamukuttan, S, Chaturvedi, N, Chen, CJ, Chen, F, Chen, S, Cheng, CY, Chetrit, A, Chiou, ST, Cho, Y, Chudek, J, Cifkova, R, Claessens, F, Concin, H, Cooper, C, Cooper, R, Costanzo, S, Cottel, D, Cowell, C, Crujeiras, AB, D'Arrigo, G, Dallongeville, J, Dankner, R, Dauchet, L, de Gaetano, G, De Henauw, S, Deepa, M, Dehghan, A, Dhana, K, Di Castelnuovo, AF, Djalalinia, S, Doua, K, Drygas, W, Du, Y, Egbagbe, EE, Eggertsen, R, El Ati, J, Elosua, R, Erasmus, RT, Erem, C, Ergor, G, Eriksen, L, Escobedo-de la Peña, J, Fall, CH, Farzadfar, F, Felix-Redondo, FJ, Ferguson, TS, Fernández-Bergés, D, Ferrari, M, Ferreccio, C, Finn, JD, Föger, B, Foo, LH, Fouad, HM, Francis, DK, Franco Mdo, C, Frontera, G, Furusawa, T, Gaciong, Z, Galbarczyk, A, Garnett, SP, Gaspoz, JM, Gasull, M, Gates, L, Geleijnse, JM, Ghasemain, A, Giampaoli, S, Gianfagna, F, Giovannelli, J, Gonzalez Gross, M, González Rivas, JP, Gorbea, MB, Gottrand, F, Grant, JF, Grodzicki, T, Grøntved, A, Gruden, G, Gu, D, Guan, OP, Guerrero, R, Guessous, I, Guimaraes, AL, Gutierrez, L, Hardy, R, Hari Kumar, R, Heidemann, C, Hihtaniemi, IT, Ho, SY, Ho, SC, Hofman, A, Horimoto, AR, Hormiga, CM, Horta, BL, Houti, L, Hussieni, AS, Huybrechts, I, Hwalla, N, Iacoviello, L, Iannone, AG, Ibrahim, MM, Ikeda, N, Ikram, MA, Irazola, VE, Islam, M, Iwasaki, M, Jacobs, JM, Jafar, T, Jasienska, G, Jiang, CQ, Jonas, JB, Joshi, P, Kafatos, A, Kalter-Leibovici, O, Kasaeian, A, Katz, J, Kaur, P, Kavousi, M, Kelishadi, R, Kengne, AP, Kersting, M, Khader, YS, Kiechl, S, Kim, J, Kiyohara, Y, Kolsteren, P, Korrovits, P, Koskinen, S, Kratzer, W, Kromhout, D, Kula, K, Kurjata, P, Kyobutungi, C, Lachat, C, Laid, Y, Lam, TH, Lanska, V, Lappas, G, Laxmaiah, A, Leclercq, C, Lee, J, Lehtimäki, T, Lekhraj, R, León-Muñoz, LM, Li, Y, Lim, WY, Lima-Costa, MF, Lin, HH, Lin, X, Lissner, L, Lorbeer, R, Lozano, JE, Lundqvist, A, Lytsy, P, Ma, G, Machado-Coelho, GL, Machi, S, Maggi, S, Makdisse, M, Mallikharjuna v, K, Manios, Y, Manzato, E, Margozzini, P, Marques-Vidal, P, Martorell, R, Masoodi, SR, Matsha, TE, Mbanya, JC, McFarlane, SR, McGarvey, ST, McLachlan, S, McNulty, BA, Mediene-Benchekor, S, Meirhaeghe, A, Menezes, AM, Merat, S, Meshram, II, Mi, J, Miquel, JF, Mohamed, MK, Mohammad, K, Mohan, V, Mohd Yusoff, MF, Møller, NC, Molnar, D, Mondo, CK, Moreno, LA, Morgan, K, Moschonis, G, Mossakowska, M, Mostafa, A, Mota, J, Muiesan, ML, Müller-Nurasyid, M, Mursu, J, Nagel, G, Námešná, J, Nang, EE, Nangia, VB, Navarrete-Muñoz, EM, Ndiaye, NC, Nervi, F, Nguyen, ND, Nieto-Martínez, RE, Alvarado, L, Ning, G, Ninomiya, T, Noale, M, Noto, D, Ochoa-Avilés, M, Oh, K, Onat, A, Osmond, C, Otero, JA, Palmieri, L, Panda-Jonas, S, Panza, F, Parsaeian, M, Peixoto, SV, Pereira, AC, Peters, A, Peykari, N, Pilav, A, Pitakaka, F, Piwonska, A, Piwonski, J, Plans-Rubió, P, Porta, M, Portegies, ML, Poustchi, H, Pradeepa, R, Price, JF, Punab, M, Qasrawi, RF, Qorbani, M, Raitakari, O, Ramachandra Rao, S, Ramachandran, A, Ramos, R, Rampal, S, Rathmann, W, Redon, J, Reganit, PF, Rigo, F, Robinson, SM, Robitaille, C, Rodríguez, LA, Rodríguez-Artalejo, F, del Cristo Rodriguez-Perez, M, Rojas-Martinez, R, Romaguera, D, Rosengren, A, Rubinstein, A, Rui, O, Ruiz-Betancourt, BS, Rutkowski, M, Sabanayagam, C, Sachdev, HS, Saidi, O, Sakarya, S, Salanave, B, Salonen, JT, Salvetti, M, Sánchez-Abanto, J, Santos, RN, Santos, R, Sardinha, LB, Scazufca, M, Schargrodsky, H, Scheidt-Nave, C, Shibuya, K, Shin, Y, Shiri, R, Siantar, R, Sibai, AM, Simon, M, Simons, J, Simons, LA, Sjostrom, M, Slowikowska-Hilczer, J, Slusarczyk, P, Smeeth, L, Snijder, MB, Solfrizzi, V, Sonestedt, E, Soumare, A, Staessen, JA, Steene-Johannessen, J, Stehle, P, Stein, AD, Stessman, J, Stöckl, D, Stokwiszewski, J, Strufaldi, MW, Sun, CA, Sundström, J, Suriyawongpaisal, P, Sy, RG, Tai, ES, Tarawneh, M, Tarqui-Mamani, CB, Thijs, L, Tolstrup, JS, Topbas, M, Torrent, M, Traissac, P, Trinh, OT, Tulloch-Reid, MK, Tuomainen, TP, Turley, ML, Tzourio, C, Ueda, P, Ukoli, FM, Ulmer, H, Valdivia, G, van Valkengoed, IG, Vanderschueren, D, Vanuzzo, D, Vega, T, Velasquez-Melendez, G, Veronesi, G, Verschuren, M, Vioque, J, Virtanen, J, Visvikis-Siest, S, Viswanathan, B, Vollenweider, P, Voutilainen, S, Wade, AN, Wagner, A, Walton, J, Mohamud, WN, Wang, MD, Wang, YX, Wannamethee, SG, Weerasekera, D, Whincup, PH, Widhalm, K, Wiecek, A, Wilks, RJ, Willeit, J, Wojtyniak, B, Wong, TY, Woo, J, Woodward, M, Wu, AG, Wu, FC, Wu, SL, Xu, H, Yang, X, Ye, X, Yoshihara, A, Younger-Coleman, NO, Zambon, S, Zargar, AH, Zdrojewski, T, Zhao, W, and Zheng, Y
- Published
- 2015
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14. Association between physical frailty and quality of life in a representative sample of community-dwelling Swiss older people
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Henchoz, Yves, Büla, C., Guessous, I., and Santos-Eggimann, B.
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- 2017
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15. Specchio-COVID19: a digital cohort study to improve public involvement in epidemiological research
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Baysson, H, primary, Pennacchhio, F, additional, Bal, A, additional, Pullen, N, additional, Lamour, J, additional, Semaani, C, additional, Zaballa, ME, additional, Graindorge, C, additional, Guessous, I, additional, and Stringhini, S, additional
- Published
- 2022
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16. Appel pour la création d’un observatoire romand des professions médicales
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Cornuz, J., Guessous, I., Reny, J.L., and Vollenweider, P.
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General Medicine - Published
- 2023
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17. No Association between Vitamin D and Weight Gain: A Prospective, Population-Based Study
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Patriota, P., Rezzi, S., Guessous, I., and Marques-Vidal, P.
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Adult ,Male ,Vitamins ,Middle Aged ,Vitamin D Deficiency ,Weight Gain ,Body Mass Index ,Aged ,Female ,Humans ,Obesity ,Prospective Studies ,Vitamin D ,Vitamin D Deficiency/epidemiology ,Waist Circumference ,epidemiology ,vitamin D ,weight gain - Abstract
The association between vitamin D and weight gain remains controversial due to important limitations in the studies. We investigated the relationship between vitamin D levels and 5 and 10 years of weight and waist circumference change in a population-based prospective cohort study. Prospective study including participants aged between 35 and 75 years living in the city of Lausanne, Switzerland. Weight and waist change at 5- and 10-year follow-up were assessed according to baseline vitamin D status (normal, insufficiency and deficiency). A total of 3638 participants (47.9 % women, mean age 51.6 ± 10.4 years) were included for the 5-year follow-up. No association was found between vitamin D categories and weight change, multivariate-adjusted average ± standard error: 1.6 ± 0.3, 1.5 ± 0.2 and 1.2 ± 0.1 kg for normal, insufficiency and deficiency, respectively, p = 0.159. For waist change, the corresponding values were 3.3 ± 0.4, 3.3 ± 0.2 and 3.4 ± 0.2 cm, p = 0.792. For the 10-year follow-up, data from 2999 participants (45.8% women, mean age 50.8 ± 10.3 years) were used. No association was found for weight 2.3 ± 0.4, 2.3 ± 0.2 and 2.0 ± 0.2 kg, p = 0.588, or for waist 3.7 ± 0.4, 3.6 ± 0.3 and 4.2 ± 0.2 cm for normal, insufficiency and deficiency, respectively, p = 0.259. No association between vitamin D status and weight or waist gain at 5- and 10-year follow-up was found.
- Published
- 2022
18. Frequency of Abnormally Low Neuropsychological Scores in Post-COVID-19 Syndrome: the Geneva COVID-COG Cohort
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Voruz, P, primary, Jacot de Alcântara, I, additional, Nuber-Champier, A, additional, Cionca, A, additional, Allali, G, additional, Benzakour, L, additional, Lalive, P H, additional, Lövblad, K-O, additional, Braillard, O, additional, Nehme, M, additional, Coen, M, additional, Serratrice, J, additional, Reny, J-L, additional, Pugin, J, additional, Guessous, I, additional, Ptak, R, additional, Landis, B N, additional, Assal, F, additional, and Péron, J A, additional
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- 2022
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19. Transient elevation of humoral responses against apolipoprotein A-1 following COVID-19 and its association with symptoms persistence
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L'Huillier, A.G., primary, Pagano, S., additional, Baggio, S., additional, Meyer, B., additional, Andrey, D.O., additional, Nehme, M., additional, Guessous, I., additional, Eberhardt, C.S., additional, Huttner, A., additional, Posfay-Barbe, K.M., additional, Yerly, S., additional, Siegrist, C.-A., additional, Kaiser, L., additional, and Vuilleumier, N., additional
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- 2022
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20. Impact of lifestyle intervention on body weight and the metabolic syndrome in home-care providers
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Gerstel, E., Pataky, Z., Busnel, C., Rutschmann, O., Guessous, I., Zumwald, C., and Golay, A.
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- 2013
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21. Association of neighbourhood disadvantage and individual socioeconomic position with all-cause mortality: a longitudinal multicohort analysis.
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Ribeiro, AI, Fraga, S, Severo, M, Kelly-Irving, M, Delpierre, C, Stringhini, S, Kivimaki, M, Joost, S, Guessous, I, Severi, G, Giles, G, Sacerdote, C, Vineis, P, Barros, H, LIFEPATH Consortium, Ribeiro, AI, Fraga, S, Severo, M, Kelly-Irving, M, Delpierre, C, Stringhini, S, Kivimaki, M, Joost, S, Guessous, I, Severi, G, Giles, G, Sacerdote, C, Vineis, P, Barros, H, and LIFEPATH Consortium
- Abstract
BACKGROUND: Few studies have examined the interactions between individual socioeconomic position and neighbourhood deprivation and the findings so far are heterogeneous. Using a large sample of diverse cohorts, we investigated the interaction effect of neighbourhood socioeconomic deprivation and individual socioeconomic position, assessed using education, on mortality. METHODS: We did a longitudinal multicohort analysis that included six cohort studies participating in the European LIFEPATH consortium: the CoLaus (Lausanne, Switzerland), E3N (France), EPIC-Turin (Turin, Italy), EPIPorto (Porto, Portugal), Melbourne Collaborative Cohort Study (Melbourne, VIC, Australia), and Whitehall II (London, UK) cohorts. All participants with data on mortality, educational attainment, and neighbourhood deprivation were included in the present study. The data sources were the databases of each cohort study. Poisson regression was used to estimate the mortality rates and associations (relative risk, 95% CIs) with neighbourhood deprivation (Q1 being least deprived to Q5 being the most deprived). Baseline educational attainment was used as an indicator of individual socioeconomic position. Estimates were combined using pooled analysis and the relative excess risk due to the interaction was computed to identify additive interactions. FINDINGS: The cohorts comprised a total population of 168 801 individuals. The recruitment dates were 2003-06 for CoLaus, 1989-91 for E3N, 1992-98 for EPIC-Turin, 1999-2003 for EPIPorto, 1990-94 for MCCS, and 1991-94 for Whitehall II. We use baseline data only and mortality data obtained using record linkage. Age-adjusted mortality rates were higher among participants residing in more deprived neighbourhoods than those in the least deprived neighbourhoods (Q1 least deprived neighbourhoods, 369·7 per 100 000 person-years [95% CI 356·4-383·2] vs Q5-most deprived neighbourhoods 445·7 per 100 000 person-years [430·2-461·7]), but the magnitude of the associat
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- 2022
22. Circulating 1,5-Anhydroglucitol as a Biomarker of ß-cell Mass Independent of a Diabetes Phenotype in Human Subjects
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Jimenez-Sanchez, C., Mezza, Teresa, Sinturel, F., Li, L., Di Giuseppe, G., Quero, Giuseppe, Jornayvaz, F. R., Guessous, I., Dibner, C., Schrauwen, P., Alfieri, Sergio, Giaccari, Andrea, Maechler, P., Mezza T. (ORCID:0000-0001-5407-9576), Quero G. (ORCID:0000-0002-0001-9479), Alfieri S. (ORCID:0000-0002-0404-724X), Giaccari A. (ORCID:0000-0002-7462-7792), Jimenez-Sanchez, C., Mezza, Teresa, Sinturel, F., Li, L., Di Giuseppe, G., Quero, Giuseppe, Jornayvaz, F. R., Guessous, I., Dibner, C., Schrauwen, P., Alfieri, Sergio, Giaccari, Andrea, Maechler, P., Mezza T. (ORCID:0000-0001-5407-9576), Quero G. (ORCID:0000-0002-0001-9479), Alfieri S. (ORCID:0000-0002-0404-724X), and Giaccari A. (ORCID:0000-0002-7462-7792)
- Abstract
Context During an asymptomatic prediabetic state, the functional ss-cell mass decreases to a critical threshold, triggering diabetes and related symptoms. To date, there are no reliable readouts able to capture in vivo a potential drop of the ss-cell mass. Objective Beside its use as a short-term marker of glycemic control, the deoxyhexose 1,5-anhydroglucitol was identified in rodents as a circulating biomarker of the functional ss-cell mass already in the asymptomatic prediabetic stage. The present study investigated the putative corresponding relevance of circulating 1,5-anhydroglucitol in different human cohorts. Methods We analyzed clinical and blood parameters in patients with established type 2 diabetes and subjects considered at high risk of developing diabetes, as well as patients with no history of diabetes scheduled for pancreaticoduodenectomy. Results Circulating 1,5-anhydroglucitol was reduced in type 2 diabetic patients, negatively correlating with fasting plasma glucose (P < 0.0001) and hemoglobin A1c (P < 0.0001). In healthy subjects, 1,5-AG levels positively correlated with body mass index (P = 0.004) and Homeostatic Model Assessment of Insulin Resistance %S (P < 0.03) and was particularly high in nondiabetic obese individuals, potentially accounting for compensatory ss-cell expansion. Patients with no history of diabetes undergoing pancreaticoduodenectomy exhibited a 50% reduction of circulating 1,5-anhydroglucitol levels following surgery leading to an acute loss of their ss-cell mass (P = 0.002), regardless their glucose tolerance status. Conclusion In summary, plasma concentration of 1,5-anhydroglucitol follows the ss-cell mass and its noninvasive monitoring may alert about the loss of ss cells in subjects at risk for diabetes, an event that cannot be captured by other clinical parameters of glycemic control.
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- 2022
23. High prevalence of forgoing healthcare for economic reasons in Switzerland: A population-based study in a region with universal health insurance coverage
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Guessous, I., Gaspoz, J.M., Theler, J.M., and Wolff, H.
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- 2012
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24. Patterns of Long COVID Symptoms: A Multi-Center Cross Sectional Study
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Yelin, D, Margalit, I, Nehme, M, Bordas-Martínez, J, Pistelli, F, Yahav, D, Guessous, I, Durà-Miralles, X, Carrozzi, L, Shapira-Lichter, I, Vetter, P, Peleato-Catalan, D, Tiseo, G, Wirtheim, E, Kaiser, L, Gudiol, C, Falcone, M, Leibovici, L and on behalf of the LongCOV Research Group: Dorit Shitenberg, Tanya, Babich, Talya, Kalfon, Michal, Mor, Yair, Shafir, Hadar, Agmon, Ori, Tishler, Donna, Abecasis, Nitzan, Karny-Epstein, Alaa, Atamna, Vered, Daitch, Laura, Tavanti, Chimera, Davide, Fideli, Antonio, Margherita, Biagini, Alessandra, Pagano, Roberta, Pancani, Massimiliano, Desideri, Nicoletta, Carpenè, Luciano, Gabbrielli, Maurizio, Lucchesi, Celi, Alessandro, Micol, Micheli, Ghiadoni, Lorenzo, Barbieri, Greta, Chiara, Romei, Annalisa, Deliperi, Monzani, Fabio, Ferruccio, Aquilini, Michele, Cristofano, Valentina, Galfo, Menichetti, Francesco, Barbieri, Chiara, Alba, Bergas, Vanessa, Vicens-Zygmunt, Cristina, Orive-Lago, Meritxell, Regi-Bosque, Ana, Peñalver-Garcia, Antonia, Requesens-Catalan, Nuria, Perez-Gutiérrez, Giovanna, Miranda, Barbara, Navarro, Eva, Alonso-Bes, Olga, Bella, Enilda, Cordero, Elena, Carrera-Izquierdo, and Sonia, Martínez-Carmona
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post-COVID ,Serveis de cures de llarga durada ,Long-term care facilities ,SARS-CoV-2 ,COVID-19 ,long lasting symptoms ,General Medicine - Abstract
Background: Long COVID has become a burden on healthcare systems worldwide. Research into the etiology and risk factors has been impeded by observing all diverse manifestations as part of a single entity. We aimed to determine patterns of symptoms in convalescing COVID-19 patients. Methods: Symptomatic patients were recruited from four countries. Data were collected regarding demographics, comorbidities, acute disease and persistent symptoms. Factor analysis was performed to elucidate symptom patterns. Associations of the patterns with patients’ characteristics, features of acute disease and effect on daily life were sought. Results: We included 1027 symptomatic post-COVID individuals in the analysis. The majority of participants were graded as having a non-severe acute COVID-19 (N = 763, 74.3%). We identified six patterns of symptoms: cognitive, pain-syndrome, pulmonary, cardiac, anosmia-dysgeusia and headache. The cognitive pattern was the major symptoms pattern, explaining 26.2% of the variance; the other patterns each explained 6.5–9.5% of the variance. The cognitive pattern was higher in patients who were outpatients during the acute disease. The pain-syndrome pattern was associated with acute disease severity, higher in women and increased with age. The pulmonary pattern was associated with prior lung disease and severe acute disease. Only two of the patterns (cognitive and cardiac) were associated with failure to return to pre-COVID occupational and physical activity status. Conclusion: Long COVID diverse symptoms can be grouped into six unique patterns. Using these patterns in future research may improve our understanding of pathophysiology and risk factors of persistent COVID, provide homogenous terminology for clinical research, and direct therapeutic interventions.
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- 2022
25. Entering an era of Precision Medicine: A needs assessment guiding design of a targeted training programme in CPD
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Mitchell, Sharon, Jaccard, E., Schmitz, Felix Michael, Guessous, I, and Guttormsen, Sissel
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610 Medizin und Gesundheit - Published
- 2022
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26. Trends in Pharmacogenomic Epidemiology : 2001–2007
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Guessous, I., Gwinn, M., Yu, W., Yeh, J., Clyne, M., and Khoury, M.J.
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- 2009
27. Médecine personnalisée et prévention des maladies chroniques - Besoins, perceptions et attentes des patients et des médecins généralistes [Personalized medicine and chronic disease prevention: Needs, attitudes and expectations regarding in general practice]
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Cohidon, C., Desvergne, B., Widmer, D., Cerqui, D., Guessous, I., and Cornuz, J.
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Attitude ,Attitude of Health Personnel ,Chronic Disease ,General Practice ,General Practitioners ,Humans ,Motivation ,Precision Medicine - Abstract
The ambition of personalized medicine now also concerns the prevention of chronic diseases, based on genetic risk profiles. The objective of this project was to describe the perception and attitudes of patients and general practitioners (GP) on this issue, in order to consider the consequences on the health system. The study included two axes, patients (questionnaire survey) and GPs (consensus study using the Delphi method), preceded by a qualitative exploratory phase. The study showed that genetic screening for disease risk factors was not a priority, either for patients or for GPs. On the other hand, the role of the GP in the use of these tests will probably be predominant. This implies the need for training and availability of up-to-date information.
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- 2021
28. Frequency of Abnormally Low Neuropsychological Scores in Post-COVID-19 Syndrome: the Geneva COVID-COG Cohort.
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Voruz, P, Alcântara, I Jacot de, Nuber-Champier, A, Cionca, A, Allali, G, Benzakour, L, Lalive, P H, Lövblad, K-O, Braillard, O, Nehme, M, Coen, M, Serratrice, J, Reny, J-L, Pugin, J, Guessous, I, Ptak, R, Landis, B N, Assal, F, and Péron, J A
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SARS-CoV-2 ,EXECUTIVE function ,CORONAVIRUS diseases ,COVID-19 pandemic ,POSTCONCUSSION syndrome - Abstract
Objective Several studies have reported poor long-term neuropsychological performances in patients following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, but none has yet considered the effect of administering multiple intercorrelated neuropsychological tests and assessed the frequency of cognitive deficits in a normative population. Our aim was therefore to assess the presence of cumulative neuropsychological deficits in an actual post-coronavirus disease of 2019 (COVID-19) comparison group versus one simulated using Monte-Carlo methods. Method Validated neuropsychological Monte-Carlo simulation methods were applied to scores from a battery of neuropsychological tests (memory, executive, attentional, perceptual, logical reasoning, language, and ideomotor praxis) administered to 121 patients who had had mild, moderate, or severe COVID-19 (mean age: 56.70 years; 32% women), 222 ± 43 days post-infection. The cumulative percentages of the three severity subgroups were compared with the results of a false discovery rate-corrected probability analysis based on normative data. Results The cumulative percentages of deficits in memory and executive functions among the severe and moderate patients were significantly higher than those estimated for the normative population. Moderate patients also had significantly more deficits in perception and logical reasoning. In contrast, the mild group did not have significantly more cumulative deficits. Conclusions Moderate and severe forms of COVID-19 cause greater long-term neuropsychological deficits than those that would be found in a normative population, reinforcing the hypothesis of long-term effects of SARS-CoV-2 on cognitive function, independent of the severity of the initial infection. [ABSTRACT FROM AUTHOR]
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- 2023
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29. Sars-CoV2- infection as a trigger of humoral response against apolipoprotein A-1
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Pagano, S, primary, Yerly, S, additional, Suh, N, additional, Le Terrier, C, additional, Farrera-Soler, L, additional, Piumatti, G, additional, Eberhardt, C S, additional, Siegrist, C A, additional, Eckerle, I, additional, Stringhini, S, additional, Guessous, I, additional, Kaiser, L, additional, Pugin, J, additional, Winssinger, N, additional, and Vuilleumier, N, additional
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- 2021
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30. SARS-COV2- infection as a trigger of humoral response against apolipoprotein A-1
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Pagano, S., primary, Yery, S., additional, Meyer, B., additional, Juillard, C., additional, Suh, N., additional, Le Terrier, C., additional, Daguer, J.-P., additional, Lluc, F.-S., additional, Barluenga, S., additional, Piumatti, G., additional, Hartley, O., additional, Lemaitre, B., additional, Eberhardt, C.S., additional, Siegrist, C.-A., additional, Eckerle, I., additional, Stringhini, S., additional, Guessous, I., additional, Kaiser, L., additional, Pugin, J., additional, Winssinger, N., additional, and Vuilleumier, N., additional
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- 2021
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31. Délibérément généralistes [Deliberately generalists]
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Guessous, I., Vollenweider, P., Reny, J.L., and Cornuz, J.
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- 2021
32. Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants
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Zhou, B, Carrillo-Larco, Rm, Danaei, G, Riley, Lm, Paciorek, Cj, Stevens, Ga, Gregg, Ew, Bennett, Je, Solomon, B, Singleton, Rk, Sophiea, Mk, Iurilli, Mlc, Lhoste, Vpf, Cowan, Mj, Savin, S, Woodward, M, Balanova, Y, Cifkova, R, Damasceno, A, Elliott, P, Farzadfar, F, He, J, Ikeda, N, Kengne, Ap, Khang, Yh, Kim, Hc, Laxmaiah, A, Lin, Hh, Maira, Pm, Miranda, Jj, Neuhauser, H, Sundstrom, J, Varghese, C, Widyahening, Is, Zdrojewski, T, Ezzati, M, Abarca-Gomez, L, Abdeen, Za, Rahim, Hfa, Abu-Rmeileh, Nm, Acosta-Cazares, B, Adams, Rj, Aekplakorn, W, Afsana, K, Afzal, S, Agdeppa, Ia, Aghazadeh-Attari, J, Aguilar-Salinas, Ca, Agyemang, C, Ahmad, Na, Ahmadi, A, Ahmadi, N, Ahmadizar, F, Ahmed, Sh, Ahrens, W, Ajlouni, K, Al-Raddadi, R, Alarouj, M, Albuhairan, F, Aldhukair, S, Ali, Mm, Alkandari, A, Alkerwi, A, Allin, K, Aly, E, Amarapurkar, Dn, Amougou, N, Amouyel, P, Andersen, Lb, Anderssen, Sa, Anjana, Rm, Ansari-Moghaddam, A, Ansong, D, Aounallah-Skhiri, H, Araujo, J, Ariansen, I, Aris, T, Arku, Re, Arlappa, N, Aryal, Kk, Aspelund, T, Assah, Fk, Assuncao, Mcf, Auvinen, J, Avdicova, M, Azevedo, A, Azimi-Nezhad, M, Azizi, F, Azmin, M, Babu, Bv, Bahijri, S, Balakrishna, N, Bamoshmoosh, M, Banach, M, Banadinovic, M, Bandosz, P, Banegas, Jr, Baran, J, Barbagallo, Cm, Barcelo, A, Barkat, A, Barreto, M, Barros, Ajd, Barros, Mvg, Bartosiewicz, A, Basit, A, Bastos, Jld, Bata, I, Batieha, Am, Batyrbek, A, Baur, La, Beaglehole, R, Belavendra, A, Ben Romdhane, H, Benet, M, Benson, Ls, Berkinbayev, S, Bernabe-Ortiz, A, Bettiol, H, Bezerra, J, Bhagyalaxmi, A, Bhargava, Sk, Bia, D, Biasch, K, Lele, Ecb, Bikbov, Mm, Bista, B, Bjerregaard, P, Bjertness, E, Bjertness, Mb, Bjorkelund, C, Bloch, Kv, Blokstra, A, Bo, S, Bobak, M, Boeing, H, Boggia, Jg, Boissonnet, Cp, Bojesen, Se, Bongard, V, Bonilla-Vargas, A, Bopp, M, Borghs, H, Bovet, P, Boyer, Cb, Braeckman, L, Brajkovich, I, Branca, F, Breckenkamp, J, Brenner, H, Brewster, Lm, Briceno, Y, Brito, M, Bruno, G, Bueno-de-Mesquita, Hb, Bueno, G, Bugge, A, Burns, C, Bursztyn, M, de Leon, Ac, Cacciottolo, J, Cameron, C, Can, G, Candido, Apc, Capanzana, Mv, Capkova, N, Capuano, E, Capuano, V, Cardoso, Vc, Carlsson, Ac, Carvalho, J, Casanueva, Ff, Censi, L, Cervantes-Loaiza, M, Chadjigeorgiou, Ca, Chamukuttan, S, Chan, Aw, Chan, Q, Chaturvedi, Hk, Chaturvedi, N, Chee, Ml, Chen, Cj, Chen, Ff, Chen, Hs, Chen, Sh, Chen, Zm, Cheng, Cy, Cheraghian, B, Dekkaki, Ic, Chetrit, A, Chien, Kl, Chiolero, A, Chiou, St, Chirita-Emandi, A, Chirlaque, Md, Cho, B, Christensen, K, Christofaro, Dg, Chudek, J, Cinteza, E, Claessens, F, Clarke, J, Clays, E, Cohen, E, Concin, H, Cooper, C, Coppinger, Tc, Costanzo, S, Cottel, D, Cowell, C, Craig, Cl, Crampin, Ac, Crujeiras, Ab, Cruz, Jj, Csilla, S, Cui, Lf, Cureau, Fv, Cuschieri, S, D'Arrigo, G, D'Orsi, E, Dallongeville, J, Dankner, R, Dantoft, Tm, Dauchet, L, Davletov, K, De Backer, G, De Bacquer, D, De Curtis, A, de Gaetano, G, De Henauw, S, de Oliveira, Pd, De Ridder, D, De Smedt, D, Deepa, M, Deev, Ad, Degennaro, V, Delisle, H, Demarest, S, Dennison, E, Deschamps, V, Dhimal, M, Di Castelnuovo, Af, Dias-da-Costa, Js, Diaz, A, Dickerson, Tt, Dika, Z, Djalalinia, S, Htp, Do, Dobson, Aj, Donfrancesco, C, Donoso, Sp, Doring, A, Dorobantu, M, Dorr, M, Doua, K, Dragano, N, Drygas, W, Duante, Ca, Duboz, P, Duda, Rb, Dulskiene, V, Dushpanova, A, Dzakula, A, Dzerve, V, Dziankowska-Zaborszczyk, E, Eddie, R, Eftekhar, E, Eggertsen, R, Eghtesad, S, Eiben, G, Ekelund, U, El-Khateeb, M, El Ati, J, Eldemire-Shearer, D, Eliasen, M, Elosua, R, Erasmus, Rt, Erbel, R, Erem, C, Eriksen, L, Eriksson, Jg, Escobedo-de la Pena, J, Eslami, S, Esmaeili, A, Evans, A, Faeh, D, Fakhretdinova, Aa, Fall, Ch, Faramarzi, E, Farjam, M, Fattahi, Mr, Fawwad, A, Felix-Redondo, Fj, Felix, Sb, Ferguson, Ts, Fernandes, Ra, Fernandez-Berges, D, Ferrante, D, Ferrao, T, Ferrari, M, Ferrario, Mm, Ferreccio, C, Ferreira, Hs, Ferrer, E, Ferrieres, J, Figueiro, Th, Fink, G, Fischer, K, Foo, Lh, Forsner, M, Fouad, Hm, Francis, Dk, Grego, Franco, Frikke-Schmidt, R, Frontera, G, Fuchs, Fd, Fuchs, Sc, Fujita, Y, Fumihiko, M, Furdela, V, Furer, A, Furusawa, T, Gaciong, Z, Galbarczyk, A, Galenkamp, H, Galvano, F, Gao, Jl, Gao, P, Garcia-de-la-Hera, M, Garcia, P, Gareta, D, Garnett, Sp, Gaspoz, Jm, Gasull, M, Gazzinelli, A, Gehring, U, Geleijnse, Jm, George, R, Ghanbari, A, Ghasemi, E, Gheorghe-Fronea, Of, Ghimire, A, Gialluisi, A, Giampaoli, S, Gieger, C, Gill, Tk, Giovannelli, J, Gironella, G, Giwercman, A, Gkiouras, K, Goldberg, M, Goldsmith, Ra, Gomez, Lf, Gomula, A, da Silva, Bgc, Goncalves, H, Goncalves, M, Gonzalez-Chica, Da, Gonzalez-Gross, M, Gonzalez-Rivas, Jp, Gonzalez-Villalpando, C, Gonzalez-Villalpando, Me, Gonzalez, Ar, Gorbea, Mb, Gottrand, F, Graff-Iversen, S, Grafnetter, D, Grajda, A, Grammatikopoulou, Mg, Gregor, Rd, Grodzicki, T, Grosso, G, Gruden, G, Df, Gu, Guan, Op, Gudmundsson, Ef, Gudnason, V, Guerrero, R, Guessous, I, Guimaraes, Al, Gulliford, Mc, Gunnlaugsdottir, J, Gunter, Mj, Gupta, Pc, Gupta, R, Gureje, O, Gurzkowska, B, Gutierrez, L, Gutzwiller, F, Ha, S, Hadaegh, F, Haghshenas, R, Hakimi, H, Halkjaer, J, Hambleton, Ir, Hamzeh, B, Hange, D, Hanif, Aam, Hantunen, S, Hao, J, Hardman, Cm, Kumar, Rh, Hashemi-Shahri, Sm, Hata, J, Haugsgjerd, T, Hayes, Aj, Yn, He, Heier, M, Hendriks, Me, Henrique, Rd, Henriques, A, Cadena, Lh, Herrala, S, Heshmat, R, Hill, Ag, Sy, Ho, Sc, Ho, Hobbs, M, Holdsworth, M, Homayounfar, R, Dinc, Gh, Horimoto, Arvr, Hormiga, Cm, Horta, Bl, Houti, L, Howitt, C, Htay, Tt, Htet, As, Htike, Mmt, Yh, Hu, Huerta, Jm, Huhtaniemi, It, Huiart, L, Huisman, M, Husseini, As, Huybrechts, I, Hwalla, N, Iacoviello, L, Iannone, Ag, Ibrahim, Mm, Wong, Ni, Ikram, Ma, Iotova, V, Irazola, Ve, Ishida, T, Isiguzo, Gc, Islam, M, Islam, Sms, Iwasaki, M, Jackson, Rt, Jacobs, Jm, Jaddou, Hy, Jafar, T, James, K, Jamrozik, K, Janszky, I, Janus, E, Jarvelin, Mr, Jasienska, G, Jelakovic, A, Jelakovic, B, Jennings, G, Jha, Ak, Jiang, Cq, Jimenez, Ro, Jockel, Kh, Joffres, M, Johansson, M, Jokelainen, Jj, Jonas, Jb, Jorgensen, T, Joshi, P, Joukar, F, Jozwiak, J, Juolevi, A, Jurak, G, Juresa, V, Kaaks, R, Kafatos, A, Kajantie, Eo, Kalmatayeva, Z, Kalpourtzi, N, Kalter-Leibovici, O, Kampmann, Fb, Kannan, S, Karaglani, E, Karhus, Ll, Karki, Kb, Katibeh, M, Katz, J, Kauhanen, J, Kaur, P, Kavousi, M, Kazakbaeva, Gm, Keil, U, Boker, Lk, Keinanen-Kiukaanniemi, S, Kelishadi, R, Kemper, Hcg, Keramati, M, Kerimkulova, A, Kersting, M, Key, T, Khader, Ys, Khalili, D, Khaw, Kt, Kheiri, B, Kheradmand, M, Khosravi, A, Kiechl-Kohlendorfer, U, Kiechl, S, Killewo, J, Kim, Dw, Kim, J, Klakk, H, Klimek, M, Klumbiene, J, Knoflach, M, Kolle, E, Kolsteren, P, Kontto, Jp, Korpelainen, R, Korrovits, P, Kos, J, Koskinen, S, Kouda, K, Kowlessur, S, Koziel, S, Kratenova, J, Kriaucioniene, V, Kristensen, Pl, Krokstad, S, Kromhout, D, Kruger, Hs, Kubinova, R, Kuciene, R, Kujala, Um, Kulaga, Z, Kumar, Rk, Kurjata, P, Kusuma, Ys, Kutsenko, V, Kuulasmaa, K, Kyobutungi, C, Laatikainen, T, Lachat, C, Laid, Y, Lam, Th, Landrove, O, Lanska, V, Lappas, G, Larijani, B, Latt, Ts, Le Coroller, G, Bao, Kln, Le, THUY DUNG, Lee, J, Lehmann, N, Lehtimaki, T, Lemogoum, D, Levitt, Ns, Yp, Li, Lilly, Cl, Lim, Wy, Lima-Costa, Mf, Lin, X, Lin, Yt, Lind, L, Lingam, V, Linneberg, A, Lissner, L, Litwin, M, Wc, Lo, Loit, Hm, Lopez-Garcia, E, Lopez, T, Lotufo, Pa, Lozano, Je, Lovrencic, Il, Lukrafka, Jl, Luksiene, D, Lundqvist, A, Lundqvist, R, Lunet, N, Lustigova, M, Luszczki, E, Gs, Ma, Ma, J, Machado-Coelho, Gll, Machado-Rodrigues, Am, Macia, E, Macieira, Lm, Madar, Aa, Maggi, S, Magliano, Dj, Magriplis, E, Mahasampath, G, Maire, B, Majer, M, Makdisse, M, Malekzadeh, F, Malekzadeh, R, Malhotra, R, Mallikharjuna, K, Malyutina, Sk, Maniego, Lv, Manios, Y, Mann, Ji, Mansour-Ghanaei, F, Manzato, E, Marcil, A, Margozzini, P, Marild, Sb, Glavic, Mm, Marques-Vidal, P, Marques, Lp, Marrugat, J, Martorell, R, Mascarenhas, Lp, Matasin, M, Mathiesen, Eb, Mathur, P, Matijasevich, A, 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Montpellier (CIHEAM-IAMM), Centre International de Hautes Études Agronomiques Méditerranéennes (CIHEAM)-Centre International de Hautes Études Agronomiques Méditerranéennes (CIHEAM)-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Interactions Gène-Environnement en Physiopathologie Cardio-Vasculaire (IGE-PCV), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL), Clinicum, Research Programs Unit, Johan Eriksson / Principal Investigator, Department of General Practice and Primary Health Care, University of Helsinki, HUS Helsinki and Uusimaa Hospital District, Department of Public Health, Tampere University, Clinical Medicine, Department of Clinical Chemistry, Eye Centre, Wellcome Trust, Epidemiology, Radiology & Nuclear Medicine, Éco-Anthropologie (EA), Cohortes épidémiologiques en population (CONSTANCES), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay-Université Paris Cité (UPCité), Université Paris Cité (UPCité), Centre International de Hautes Études Agronomiques Méditerranéennes (CIHEAM)-Centre International de Hautes Études Agronomiques Méditerranéennes (CIHEAM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut Agro - Montpellier SupAgro, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Epidemiology and Data Science, APH - Aging & Later Life, APH - Societal Participation & Health, Public and occupational health, APH - Health Behaviors & Chronic Diseases, VU University medical center, APH - Personalized Medicine, Psychiatry, APH - Mental Health, Bin Zhou, Rodrigo M Carrillo-Larco, Goodarz Danaei, Leanne M Riley, Christopher J Paciorek, Gretchen A Stevens, Edward W Gregg, James E Bennett, Bethlehem Solomon, Rosie K Singleton, Marisa K Sophiea, Maria Lc Iurilli, Victor Pf Lhoste, Melanie J Cowan, Stefan Savin, Mark Woodward, Yulia Balanova, Renata Cifkova, Albertino Damasceno, Paul Elliott, Farshad Farzadfar, Jiang He, Nayu Ikeda, Andre P Kengne, Young-Ho Khang, Hyeon Chang Kim, Avula Laxmaiah, Hsien-Ho Lin, Paula Margozzini Maira, J Jaime Miranda, Hannelore Neuhauser, Johan Sundström, Cherian Varghese, Indah S Widyahening, Tomasz Zdrojewski, Leandra Abarca-Gómez, Ziad A Abdeen, Hanan F Abdul Rahim, Niveen M Abu-Rmeileh, Benjamin Acosta-Cazares, Robert J Adams, Wichai Aekplakorn, Kaosar Afsana, Shoaib Afzal, Imelda A Agdeppa, Javad Aghazadeh-Attari, Carlos A Aguilar-Salinas, Charles Agyemang, Noor Ani Ahmad, Ali Ahmadi, Naser Ahmadi, Nastaran Ahmadi, Fariba Ahmadizar, Soheir H Ahmed, Wolfgang Ahrens, Kamel Ajlouni, Rajaa Al-Raddadi, Monira Alarouj, Fadia AlBuhairan, Shahla AlDhukair, Mohamed M Ali, Abdullah Alkandari, Ala'a Alkerwi, Kristine Allin, Eman Aly, Deepak N Amarapurkar, Norbert Amougou, Philippe Amouyel, Lars Bo Andersen, Sigmund A Anderssen, Ranjit Mohan Anjana, Alireza Ansari-Moghaddam, Daniel Ansong, Hajer Aounallah-Skhiri, Joana Araújo, Inger Ariansen, Tahir Aris, Raphael E Arku, Nimmathota Arlappa, Krishna K Aryal, Thor Aspelund, Felix K Assah, Maria Cecília F Assunção, Juha Auvinen, Mária Avdićová, Ana Azevedo, Mohsen Azimi-Nezhad, Fereidoun Azizi, Mehrdad Azmin, Bontha V Babu, Suhad Bahijri, Nagalla Balakrishna, Mohamed Bamoshmoosh, Maciej Banach, Maja Banadinović, Piotr Bandosz, José R Banegas, Joanna Baran, Barbagallo Carlo Maria, Alberto Barceló, Amina Barkat, Marta Barreto, Aluisio Jd Barros, Mauro Virgílio Gomes Barros, Anna Bartosiewicz, Abdul Basit, Joao Luiz D Bastos, Iqbal Bata, Anwar M Batieha, Assembekov Batyrbek, Louise A Baur, Robert Beaglehole, Antonisamy Belavendra, Habiba Ben Romdhane, Mikhail Benet, Lowell S Benson, Salim Berkinbayev, Antonio Bernabe-Ortiz, Gailute Bernotiene, Heloísa Bettiol, Jorge Bezerra, Aroor Bhagyalaxmi, Santosh K Bhargava, Daniel Bia, Katia Biasch, Elysée Claude Bika Lele, Mukharram M Bikbov, Bihungum Bista, Peter Bjerregaard, Espen Bjertness, Marius B Bjertness, Cecilia Björkelund, Katia V Bloch, Anneke Blokstra, Simona Bo, Martin Bobak, Heiner Boeing, Jose G Boggia, Carlos P Boissonnet, Stig E Bojesen, Vanina Bongard, Alice Bonilla-Vargas, Matthias Bopp, Herman Borghs, Pascal Bovet, Christopher B Boyer, Lutgart Braeckman, Imperia Brajkovich, Francesco Branca, Juergen Breckenkamp, Hermann Brenner, Lizzy M Brewster, Yajaira Briceño, Miguel Brito, Graziella Bruno, H Bas Bueno-de-Mesquita, Gloria Bueno, Anna Bugge, Con Burns, Michael Bursztyn, Antonio Cabrera de León, Joseph Cacciottolo, Christine Cameron, Günay Can, Ana Paula C Cândido, Mario V Capanzana, Naděžda Čapková, Eduardo Capuano, Vincenzo Capuano, Viviane C Cardoso, Axel C Carlsson, Joana Carvalho, Felipe F Casanueva, Laura Censi, Marvin Cervantes-Loaiza, Charalambos A Chadjigeorgiou, Snehalatha Chamukuttan, Angelique W Chan, Queenie Chan, Himanshu K Chaturvedi, Nish Chaturvedi, Miao Li Chee, Chien-Jen Chen, Fangfang Chen, Huashuai Chen, Shuohua Chen, Zhengming Chen, Ching-Yu Cheng, Bahman Cheraghian, Imane Cherkaoui Dekkaki, Angela Chetrit, Kuo-Liong Chien, Arnaud Chiolero, Shu-Ti Chiou, Adela Chirita-Emandi, María-Dolores Chirlaque, Belong Cho, Kaare Christensen, Diego G Christofaro, Jerzy Chudek, Eliza Cinteza, Frank Claessens, Janine Clarke, Els Clays, Emmanuel Cohen, Hans Concin, Cyrus Cooper, Tara C Coppinger, Simona Costanzo, Dominique Cottel, Chris Cowell, Cora L Craig, Amelia C Crampin, Ana B Crujeiras, Juan J Cruz, Semánová Csilla, Liufu Cui, Felipe V Cureau, Sarah Cuschieri, Graziella D'Arrigo, Eleonora d'Orsi, Jean Dallongeville, Rachel Dankner, Thomas M Dantoft, Luc Dauchet, Kairat Davletov, Guy De Backer, Dirk De Bacquer, Amalia De Curtis, Giovanni de Gaetano, Stefaan De Henauw, Paula Duarte de Oliveira, David De Ridder, Delphine De Smedt, Mohan Deepa, Alexander D Deev, Vincent Jr DeGennaro, Hélène Delisle, Stefaan Demarest, Elaine Dennison, Valérie Deschamps, Meghnath Dhimal, Augusto F Di Castelnuovo, Juvenal Soares Dias-da-Costa, Alejandro Diaz, Ty T Dickerson, Zivka Dika, Shirin Djalalinia, Ha Tp Do, Annette J Dobson, Chiara Donfrancesco, Silvana P Donoso, Angela Döring, Maria Dorobantu, Marcus Dörr, Kouamelan Doua, Nico Dragano, Wojciech Drygas, Charmaine A Duante, Priscilla Duboz, Rosemary B Duda, Virginija Dulskiene, Anar Dushpanova, Aleksandar Džakula, Vilnis Dzerve, Elzbieta Dziankowska-Zaborszczyk, Ricky Eddie, Ebrahim Eftekhar, Robert Eggertsen, Sareh Eghtesad, Gabriele Eiben, Ulf Ekelund, Mohammad El-Khateeb, Jalila El Ati, Denise Eldemire-Shearer, Marie Eliasen, Roberto Elosua, Rajiv T Erasmus, Raimund Erbel, Cihangir Erem, Louise Eriksen, Johan G Eriksson, Jorge Escobedo-de la Peña, Saeid Eslami, Ali Esmaeili, Alun Evans, David Faeh, Albina A Fakhretdinova, Caroline H Fall, Elnaz Faramarzi, Mojtaba Farjam, Mohammad Reza Fattahi, Asher Fawwad, Francisco J Felix-Redondo, Stephan B Felix, Trevor S Ferguson, Romulo A Fernandes, Daniel Fernández-Bergés, Daniel Ferrante, Thomas Ferrao, Marika Ferrari, Marco M Ferrario, Catterina Ferreccio, Haroldo S Ferreira, Eldridge Ferrer, Jean Ferrieres, Thamara Hubler Figueiró, Günther Fink, Krista Fischer, Leng Huat Foo, Maria Forsner, Heba M Fouad, Damian K Francis, Maria do Carmo Franco, Ruth Frikke-Schmidt, Guillermo Frontera, Flavio D Fuchs, Sandra C Fuchs, Yuki Fujita, Matsuda Fumihiko, Viktoriya Furdela, Ariel Furer, Takuro Furusawa, Zbigniew Gaciong, Andrzej Galbarczyk, Henrike Galenkamp, Fabio Galvano, Jingli Gao, Pei Gao, Manoli Garcia-de-la-Hera, Pablo Garcia, Dickman Gareta, Sarah P Garnett, Jean-Michel Gaspoz, Magda Gasull, Andrea Gazzinelli, Ulrike Gehring, Johanna M Geleijnse, Ronnie George, Ali Ghanbari, Erfan Ghasemi, Oana-Florentina Gheorghe-Fronea, Anup Ghimire, Alessandro Gialluisi, Simona Giampaoli, Christian Gieger, Tiffany K Gill, Jonathan Giovannelli, Glen Gironella, Aleksander Giwercman, Konstantinos Gkiouras, Marcel Goldberg, Rebecca A Goldsmith, Luis F Gomez, Aleksandra Gomula, Helen Gonçalves, Mauer Gonçalves, Bruna Gonçalves Cordeiro da Silva, David A Gonzalez-Chica, Marcela Gonzalez-Gross, Juan P González-Rivas, Clicerio González-Villalpando, María-Elena González-Villalpando, Angel R Gonzalez, Mariano Bonet Gorbea, Frederic Gottrand, Sidsel Graff-Iversen, Dušan Grafnetter, Aneta Grajda, Maria G Grammatikopoulou, Ronald D Gregor, Tomasz Grodzicki, Giuseppe Grosso, Gabriella Gruden, Dongfeng Gu, Ong Peng Guan, Elias F Gudmundsson, Vilmundur Gudnason, Ramiro Guerrero, Idris Guessous, Andre L Guimaraes, Martin C Gulliford, Johanna Gunnlaugsdottir, Marc J Gunter, Prakash C Gupta, Rajeev Gupta, Oye Gureje, Beata Gurzkowska, Laura Gutierrez, Felix Gutzwiller, Seongjun Ha, Farzad Hadaegh, Rosa Haghshenas, Hamid Hakimi, Jytte Halkjær, Ian R Hambleton, Behrooz Hamzeh, Dominique Hange, Abu Am Hanif, Sari Hantunen, Jie Hao, Carla Menêses Hardman, Rachakulla Hari Kumar, Seyed Mohammad Hashemi-Shahri, Jun Hata, Teresa Haugsgjerd, Alison J Hayes, Yuna He, Margit Heier, Marleen Elisabeth Hendriks, Rafael Dos Santos Henrique, Ana Henriques, Leticia Hernandez Cadena, Herqutanto, Sauli Herrala, Ramin Heshmat, Allan G Hill, Sai Yin Ho, Suzanne C Ho, Michael Hobbs, Michelle Holdsworth, Reza Homayounfar, Gonul Horasan Dinc, Andrea Rvr Horimoto, Claudia M Hormiga, Bernardo L Horta, Leila Houti, Christina Howitt, Thein Thein Htay, Aung Soe Htet, Maung Maung Than Htike, Yonghua Hu, José María Huerta, Ilpo Tapani Huhtaniemi, Laetitia Huiart, Martijn Huisman, Abdullatif S Husseini, Inge Huybrechts, Nahla Hwalla, Licia Iacoviello, Anna G Iannone, Mohsen M Ibrahim, Norazizah Ibrahim Wong, M Arfan Ikram, Violeta Iotova, Vilma E Irazola, Takafumi Ishida, Godsent C Isiguzo, Muhammad Islam, Sheikh Mohammed Shariful Islam, Masanori Iwasaki, Rod T Jackson, Jeremy M Jacobs, Hashem Y Jaddou, Tazeen Jafar, Kenneth James, Konrad Jamrozik, Imre Janszky, Edward Janus, Marjo-Riitta Jarvelin, Grazyna Jasienska, Ana Jelaković, Bojan Jelaković, Garry Jennings, Anjani Kumar Jha, Chao Qiang Jiang, Ramon O Jimenez, Karl-Heinz Jöckel, Michel Joffres, Mattias Johansson, Jari J Jokelainen, Jost B Jonas, Torben Jørgensen, Pradeep Joshi, Farahnaz Joukar, Jacek Jóżwiak, Anne Juolevi, Gregor Jurak, Vesna Jureša, Rudolf Kaaks, Anthony Kafatos, Eero O Kajantie, Zhanna Kalmatayeva, Natasa Kalpourtzi, Ofra Kalter-Leibovici, Freja B Kampmann, Srinivasan Kannan, Eva Karaglani, Line L Kårhus, Khem B Karki, Marzieh Katibeh, Joanne Katz, Jussi Kauhanen, Prabhdeep Kaur, Maryam Kavousi, Gyulli M Kazakbaeva, Ulrich Keil, Lital Keinan Boker, Sirkka Keinänen-Kiukaanniemi, Roya Kelishadi, Han Cg Kemper, Maryam Keramati, Alina Kerimkulova, Mathilde Kersting, Timothy Key, Yousef Saleh Khader, Davood Khalili, Kay-Tee Khaw, Bahareh Kheiri, Motahareh Kheradmand, Alireza Khosravi, Ursula Kiechl-Kohlendorfer, Stefan Kiechl, Japhet Killewo, Dong Wook Kim, Jeongseon Kim, Heidi Klakk, Magdalena Klimek, Jurate Klumbiene, Michael Knoflach, Elin Kolle, Patrick Kolsteren, Jukka P Kontto, Raija Korpelainen, Paul Korrovits, Jelena Kos, Seppo Koskinen, Katsuyasu Kouda, Sudhir Kowlessur, Slawomir Koziel, Jana Kratenova, Vilma Kriaucioniene, Peter Lund Kristensen, Steiner Krokstad, Daan Kromhout, Herculina S Kruger, Ruzena Kubinova, Renata Kuciene, Urho M Kujala, Zbigniew Kulaga, R Krishna Kumar, Pawel Kurjata, Yadlapalli S Kusuma, Vladimir Kutsenko, Kari Kuulasmaa, Catherine Kyobutungi, Tiina Laatikainen, Carl Lachat, Youcef Laid, Tai Hing Lam, Orlando Landrove, Vera Lanska, Georg Lappas, Bagher Larijani, Tint Swe Latt, Gwenaëlle Le Coroller, Khanh Le Nguyen Bao, Tuyen D Le, Jeannette Lee, Jeonghee Lee, Nils Lehmann, Terho Lehtimäki, Daniel Lemogoum, Naomi S Levitt, Yanping Li, Christa L Lilly, Wei-Yen Lim, M Fernanda Lima-Costa, Xu Lin, Yi-Ting Lin, Lars Lind, Vijaya Lingam, Allan Linneberg, Lauren Lissner, Mieczyslaw Litwin, Wei-Cheng Lo, Helle-Mai Loit, Esther Lopez-Garcia, Tania Lopez, Paulo A Lotufo, José Eugenio Lozano, Iva Lukačević Lovrenčić, Janice L Lukrafka, Dalia Luksiene, Annamari Lundqvist, Robert Lundqvist, Nuno Lunet, Michala Lustigová, Edyta Luszczki, Guansheng Ma, Jun Ma, George Ll Machado-Coelho, Aristides M Machado-Rodrigues, Enguerran Macia, Luisa M Macieira, Ahmed A Madar, Stefania Maggi, Dianna J Magliano, Emmanuella Magriplis, Gowri Mahasampath, Bernard Maire, Marjeta Majer, Marcia Makdisse, Fatemeh Malekzadeh, Reza Malekzadeh, Rahul Malhotra, Kodavanti Mallikharjuna Rao, Sofia K Malyutina, Lynell V Maniego, Yannis Manios, Jim I Mann, Fariborz Mansour-Ghanaei, Enzo Manzato, Anie Marcil, Staffan B Mårild, Mihalea Marinović Glavić, Pedro Marques-Vidal, Larissa Pruner Marques, Jaume Marrugat, Reynaldo Martorell, Luis P Mascarenhas, Marija Matasin, Ellisiv B Mathiesen, Prashant Mathur, Alicia Matijasevich, Piotr Matlosz, Tandi E Matsha, Christina Mavrogianni, Jean Claude N Mbanya, Anselmo J Mc Donald Posso, Shelly R McFarlane, Stephen T McGarvey, Stela McLachlan, Rachael M McLean, Scott B McLean, Breige A McNulty, Sounnia Mediene Benchekor, Jurate Medzioniene, Parinaz Mehdipour, Kirsten Mehlig, Amir Houshang Mehrparvar, Aline Meirhaeghe, Christa Meisinger, Carlos Mendoza Montano, Ana Maria B Menezes, Geetha R Menon, Alibek Mereke, Indrapal I Meshram, Andres Metspalu, Haakon E Meyer, Jie Mi, Nathalie Michels, Kairit Mikkel, Karolina Milkowska, Jody C Miller, Cláudia S Minderico, G K Mini, Mohammad Reza Mirjalili, Erkin Mirrakhimov, Marjeta Mišigoj-Duraković, Pietro A Modesti, Sahar Saeedi Moghaddam, Bahram Mohajer, Mostafa K Mohamed, Shukri F Mohamed, Kazem Mohammad, Mohammad Reza Mohammadi, Zahra Mohammadi, Noushin Mohammadifard, Reza Mohammadpourhodki, Viswanathan Mohan, Salim Mohanna, Muhammad Fadhli Mohd Yusoff, Iraj Mohebbi, Farnam Mohebi, Marie Moitry, Line T Møllehave, Dénes Molnár, Amirabbas Momenan, Charles K Mondo, Eric Monterrubio-Flores, Kotsedi Daniel K Monyeki, Jin Soo Moon, Mahmood Moosazadeh, Leila B Moreira, Alain Morejon, Luis A Moreno, Karen Morgan, George Moschonis, Malgorzata Mossakowska, Aya Mostafa, Seyed-Ali Mostafavi, Jorge Mota, Mohammad Esmaeel Motlagh, Jorge Motta, Marcos André Moura-Dos-Santos, Malay K Mridha, Kelias P Msyamboza, Thet Thet Mu, Alfa J Muhihi, Maria L Muiesan, Martina Müller-Nurasyid, Neil Murphy, Jaakko Mursu, Kamarul Imran Musa, Sanja Musić Milanović, Vera Musil, Norlaila Mustafa, Iraj Nabipour, Shohreh Naderimagham, Gabriele Nagel, Balkish M Naidu, Farid Najafi, Harunobu Nakamura, Jana Námešná, Ei Ei K Nang, Vinay B Nangia, Sameer Narake, Ndeye Coumba Ndiaye, William A Neal, Azim Nejatizadeh, Ilona Nenko, Martin Neovius, Chung T Nguyen, Nguyen D Nguyen, Quang V Nguyen, Quang Ngoc Nguyen, Ramfis E Nieto-Martínez, Teemu J Niiranen, Yury P Nikitin, Toshiharu Ninomiya, Sania Nishtar, Marina A Njelekela, Marianna Noale, Oscar A Noboa, Ahmad Ali Noorbala, Teresa Norat, Maria Nordendahl, Børge G Nordestgaard, Noto Davide, Natalia Nowak-Szczepanska, Mohannad Al Nsour, Baltazar Nunes, Terence W O'Neill, Dermot O'Reilly, Caleb Ochimana, Eiji Oda, Augustine N Odili, Kyungwon Oh, Kumiko Ohara, Ryutaro Ohtsuka, Valérie Olié, Maria Teresa A Olinto, Isabel O Oliveira, Mohd Azahadi Omar, Altan Onat, Sok King Ong, Lariane M Ono, Pedro Ordunez, Rui Ornelas, Pedro J Ortiz, Clive Osmond, Sergej M Ostojic, Afshin Ostovar, Johanna A Otero, Kim Overvad, Ellis Owusu-Dabo, Fred Michel Paccaud, Cristina Padez, Elena Pahomova, Karina Mary de Paiva, Andrzej Pająk, Domenico Palli, Luigi Palmieri, Wen-Harn Pan, Songhomitra Panda-Jonas, Francesco Panza, Mariela Paoli, Dimitrios Papandreou, Soon-Woo Park, Suyeon Park, Winsome R Parnell, Mahboubeh Parsaeian, Patrick Pasquet, Nikhil D Patel, Halyna Pavlyshyn, Ivan Pećin, Mangesh S Pednekar, João M Pedro, Nasheeta Peer, Sergio Viana Peixoto, Markku Peltonen, Alexandre C Pereira, Karen Gda Peres, Marco A Peres, Annette Peters, Janina Petkeviciene, Niloofar Peykari, Son Thai Pham, Rafael N Pichardo, Iris Pigeot, Hynek Pikhart, Aida Pilav, Lorenza Pilotto, Freda Pitakaka, Aleksandra Piwonska, Andreia N Pizarro, Pedro Plans-Rubió, Ozren Polašek, Miquel Porta, Anil Poudyal, Farhad Pourfarzi, Akram Pourshams, Hossein Poustchi, Rajendra Pradeepa, Alison J Price, Jacqueline F Price, Rui Providencia, Soile E Puhakka, Maria Puiu, Margus Punab, Radwan F Qasrawi, Mostafa Qorbani, Daniel Queiroz, Tran Quoc Bao, Ivana Radić, Ricardas Radisauskas, Salar Rahimikazerooni, Mahfuzar Rahman, Olli Raitakari, Manu Raj, Ellina M Rakhimova, Sudha Ramachandra Rao, Ambady Ramachandran, Elisabete Ramos, Lekhraj Rampal, Sanjay Rampal, Daniel A Rangel Reina, Vayia Rarra, Cassiano Ricardo Rech, Josep Redon, Paul Ferdinand M Reganit, Valéria Regecová, Luis Revilla, Abbas Rezaianzadeh, Robespierre Ribeiro, Elio Riboli, Adrian Richter, Fernando Rigo, Tobias F Rinke de Wit, Raphael M Ritti-Dias, Cynthia Robitaille, Fernando Rodríguez-Artalejo, María Del Cristo Rodriguez-Perez, Laura A Rodríguez-Villamizar, Ulla Roggenbuck, Rosalba Rojas-Martinez, Dora Romaguera, Elisabetta L Romeo, Annika Rosengren, Joel Gr Roy, Adolfo Rubinstein, Jean-Bernard Ruidavets, Blanca Sandra Ruiz-Betancourt, Maria Ruiz-Castell, Iuliia A Rusakova, Paola Russo, Marcin Rutkowski, Charumathi Sabanayagam, Hamideh Sabbaghi, Harshpal S Sachdev, Alireza Sadjadi, Ali Reza Safarpour, Sare Safi, Saeid Safiri, Olfa Saidi, Sibel Sakarya, Nader Saki, Benoit Salanave, Eduardo Salazar Martinez, Diego Salmerón, Veikko Salomaa, Jukka T Salonen, Massimo Salvetti, Jose Sánchez-Abanto, Susana Sans, Diana A Santos, Ina S Santos, Lèlita C Santos, Maria Paula Santos, Rute Santos, Jouko L Saramies, Luis B Sardinha, Giselle Sarganas, Nizal Sarrafzadegan, Thirunavukkarasu Sathish, Kai-Uwe Saum, Savvas Savva, Norie Sawada, Mariana Sbaraini, Marcia Scazufca, Beatriz D Schaan, Herman Schargrodsky, Sabine Schipf, Carsten O Schmidt, Peter Schnohr, Ben Schöttker, Sara Schramm, Constance Schultsz, Aletta E Schutte, Sylvain Sebert, Aye Aye Sein, Abhijit Sen, Idowu O Senbanjo, Sadaf G Sepanlou, Jennifer Servais, Svetlana A Shalnova, Teresa Shamah-Levy, Morteza Shamshirgaran, Coimbatore Subramaniam Shanthirani, Maryam Sharafkhah, Sanjib K Sharma, Jonathan E Shaw, Amaneh Shayanrad, Ali Akbar Shayesteh, Zumin Shi, Kenji Shibuya, Hana Shimizu-Furusawa, Dong Wook Shin, Majid Shirani, Rahman Shiri, Namuna Shrestha, Khairil Si-Ramlee, Alfonso Siani, Rosalynn Siantar, Abla M Sibai, Caroline Ramos de Moura Silva, Diego Augusto Santos Silva, Mary Simon, Judith Simons, Leon A Simons, Michael Sjöström, Jolanta Slowikowska-Hilczer, Przemyslaw Slusarczyk, Liam Smeeth, Hung-Kwan So, Fernanda Cunha Soares, Eugène Sobngwi, Stefan Söderberg, Agustinus Soemantri, Reecha Sofat, Vincenzo Solfrizzi, Mohammad Hossein Somi, Emily Sonestedt, Yi Song, Thorkild Ia Sørensen, Elin P Sørgjerd, Maroje Sorić, Charles Sossa Jérome, Aïcha Soumaré, Bente Sparboe-Nilsen, Karen Sparrenberger, Jan A Staessen, Gregor Starc, Bill Stavreski, Jostein Steene-Johannessen, Peter Stehle, Aryeh D Stein, George S Stergiou, Jochanan Stessman, Jutta Stieber, Doris Stöckl, Tanja Stocks, Jakub Stokwiszewski, Karien Stronks, Maria Wany Strufaldi, Machi Suka, Chien-An Sun, Yn-Tz Sung, Paibul Suriyawongpaisal, Rody G Sy, Holly E Syddall, René Charles Sylva, Moyses Szklo, E Shyong Tai, Mari-Liis Tammesoo, Abdonas Tamosiunas, Eng Joo Tan, Xun Tang, Frank Tanser, Yong Tao, Mohammed Rasoul Tarawneh, Carolina B Tarqui-Mamani, Anne Taylor, Julie Taylor, William R Tebar, Grethe S Tell, Tania Tello, Yih Chung Tham, K R Thankappan, Holger Theobald, Xenophon Theodoridis, Lutgarde Thijs, 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Yoshihara, San-Lin You, Novie O Younger-Coleman, Ahmad Faudzi Yusoff, Ahmad A Zainuddin, Seyed Rasoul Zakavi, Farhad Zamani, Sabina Zambon, Antonis Zampelas, Maria Elisa Zapata, Ko Ko Zaw, Kristyna Zejglicova, Tajana Zeljkovic Vrkic, Yi Zeng, Luxia Zhang, Zhen-Yu Zhang, Dong Zhao, Ming-Hui Zhao, Shiqi Zhen, Yingfeng Zheng, Bekbolat Zholdin, Dan Zhu, Marie Zins, Emanuel Zitt, Yanina Zocalo, Nada Zoghlami, Julio Zuñiga Cisneros, Majid Ezzati, Sakarya, Sibel (ORCID 0000-0002-9959-6240 & YÖK ID 172028), Zhou, Bin, Carrillo-Larco, Rodrigo M., Danaei, Goodarz, Riley, Leanne M., Paciorek, Christopher J., Stevens, Gretchen A., Gregg, Edward W., Bennett, James E., Solomon, Bethlehem, Singleton, Rosie K., Sophiea, Marisa K., Iurilli, Maria L. 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A., Peres, Marco A., Peters, Annette, Petkeviciene, Janina, Peykari, Niloofar, Son Thai Pham, Pichardo, Rafael N., Pigeot, Iris, Pikhart, Hynek, Pilav, Aida, Pilotto, Lorenza, Pitakaka, Freda, Piwonska, Aleksandra, Pizarro, Andreia N., Plans-Rubio, Pedro, Polasek, Ozren, Porta, Miquel, Poudyal, Anil, Pourfarzi, Farhad, Pourshams, Akram, Poustchi, Hossein, Pradeepa, Rajendra, Price, Alison J., Price, Jacqueline F., Providencia, Rui, Puhakka, Soile E., Puiu, Maria, Punab, Margus, Qasrawi, Radwan F., Qorbani, Mostafa, Queiroz, Daniel, Tran Quoc Bao, Radic, Ivana, Radisauskas, Ricardas, Rahimikazerooni, Salar, Rahman, Mahfuzar, Raitakari, Olli, Raj, Manu, Rakhimova, Ellina M., Rao, Sudha Ramachandra, Ramachandran, Ambady, Ramos, Elisabete, Rampal, Lekhraj, Rampal, Sanjay, Rangel Reina, Daniel A., Rarra, Vayia, Rech, Cassiano Ricardo, Redon, Josep, Reganit, Paul Ferdinand M., Regecova, Valeria, Revilla, Luis, Rezaianzadeh, Abbas, Ribeiro, Robespierre, Riboli, Elio, Richter, Adrian, Rigo, Fernando, de Wit, Tobias F. Rinke, Ritti-Dias, Raphael M., Robitaille, Cynthia, Rodriguez-Artalejo, Fernando, del Cristo Rodriguez-Perez, Maria, Rodriguez-Villamizar, Laura A., Roggenbuck, Ulla, Rojas-Martinez, Rosalba, Romaguera, Dora, Romeo, Elisabetta L., Rosengren, Annika, Roy, Joel G. R., Rubinstein, Adolfo, Ruidavets, Jean-Bernard, Sandra Ruiz-Betancourt, Blanca, Ruiz-Castell, Maria, Rusakova, Iuliia A., Russo, Paola, Rutkowski, Marcin, Sabanayagam, Charumathi, Sabbaghi, Hamideh, Sachdev, Harshpal S., Sadjadi, Alireza, Safarpour, Ali Reza, Safi, Sare, Safiri, Saeid, Saidi, Olfa, Saki, Nader, Salanave, Benoit, Salazar Martinez, Eduardo, Salmeron, Diego, Salomaa, Veikko, Salonen, Jukka T., Salvetti, Massimo, Sanchez-Abanto, Jose, Sans, Susana, Santos, Diana A., Santos, Ina S., Santos, Lelita C., Santos, Maria Paula, Santos, Rute, Saramies, Jouko L., Sardinha, Luis B., Sarganas, Giselle, Sarrafzadegan, Nizal, Sathish, Thirunavukkarasu, Saum, Kai-Uwe, Savva, Savvas, Sawada, Norie, Sbaraini, Mariana, Scazufca, Marcia, Schaan, Beatriz D., Schargrodsky, Herman, Schipf, Sabine, Schmidt, Carsten O., Schnohr, Peter, Schoettker, Ben, Schramm, Sara, Schultsz, Constance, Schutte, Aletta E., Sebert, Sylvain, Sein, Aye Aye, Sen, Abhijit, Senbanjo, Idowu O., Sepanlou, Sadaf G., Servais, Jennifer, Shalnova, Svetlana A., Shamah-Levy, Teresa, Shamshirgaran, Morteza, Shanthirani, Coimbatore Subramaniam, Sharafkhah, Maryam, Sharma, Sanjib K., Shaw, Jonathan E., Shayanrad, Amaneh, Shayesteh, Ali Akbar, Shi, Zumin, Shibuya, Kenji, Shimizu-Furusawa, Hana, Shin, Dong Wook, Shirani, Majid, Shiri, Rahman, Shrestha, Namuna, Si-Ramlee, Khairil, Siani, Alfonso, Siantar, Rosalynn, Sibai, Abla M., de Moura Silva, Caroline Ramos, Santos Silva, Diego Augusto, Simon, Mary, Simons, Judith, Simons, Leon A., Sjostrom, Michael, Slowikowska-Hilczer, Jolanta, Slusarczyk, Przemyslaw, Smeeth, Liam, So, Hung-Kwan, Soares, Fernanda Cunha, Sobngwi, Eugene, Soderberg, Stefan, Soemantri, Agustinus, Sofat, Reecha, Solfrizzi, Vincenzo, Somi, Mohammad Hossein, Sonestedt, Emily, Song, Yi, Sorensen, Thorkild I. 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Male ,Latin Americans ,Nutrition and Disease ,Epidemiology ,[SDV]Life Sciences [q-bio] ,Medizin ,BLOOD-PRESSURE ,030204 cardiovascular system & hematology ,Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants ,Hypertension ,Prevalence ,Control ,Tretament ,GUIDELINES ,Global Health ,Worldwide trends ,0302 clinical medicine ,Hypertension prevalence ,Voeding en Ziekte ,Medicine and Health Sciences ,kohonnut verenpaine ,Medicine ,030212 general & internal medicine ,Prevention and Control ,11 Medical and Health Sciences ,ComputingMilieux_MISCELLANEOUS ,education.field_of_study ,food and beverages ,Public Health, Global Health, Social Medicine and Epidemiology ,General Medicine ,Noncommunicable diseases ,Period prevalence ,Middle Aged ,kansainvälinen vertailu ,3142 Public health care science, environmental and occupational health ,3. Good health ,MIDDLE-INCOME ,Pooled analysis ,SYSTEMATIC ANALYSIS ,INCOME COUNTRIES ,ADULTS ,PREVENTION ,MANAGEMENT ,ADHERENCE ,DIAGNOSIS ,Western europe ,[SDE]Environmental Sciences ,Hypertension/diagnosis ,NCD Risk Factor Collaboration (NCD-RisC) ,Female ,B990 Subjects Allied to Medicine not elsewhere classified ,Life Sciences & Biomedicine ,Adult ,health-care ,esiintyvyys ,Central asia ,Population ,Nursing ,3121 Internal medicine ,03 medical and health sciences ,Medicine, General & Internal ,Drug Therapy ,General & Internal Medicine ,Life Science ,Humans ,ddc:610 ,education ,Antihypertensive Agents ,VLAG ,Aged ,Science & Technology ,Antihypertensive Agents/therapeutic use ,business.industry ,Omvårdnad ,fungi ,General and internal medicine ,Estados de Saúde e de Doença ,Taking medication ,Treatment ,Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi ,Blood pressure ,Faculdade de Ciências Sociais ,3121 General medicine, internal medicine and other clinical medicine ,lääkehoito ,1182 Biochemistry, cell and molecular biology ,business ,Demography - Abstract
Background: hypertension can be detected at the primary health-care level and low-cost treatments can effectively control hypertension. We aimed to measure the prevalence of hypertension and progress in its detection, treatment, and control from 1990 to 2019 for 200 countries and territories. Methods: we used data from 1990 to 2019 on people aged 30-79 years from population-representative studies with measurement of blood pressure and data on blood pressure treatment. We defined hypertension as having systolic blood pressure 140 mm Hg or greater, diastolic blood pressure 90 mm Hg or greater, or taking medication for hypertension. We applied a Bayesian hierarchical model to estimate the prevalence of hypertension and the proportion of people with hypertension who had a previous diagnosis (detection), who were taking medication for hypertension (treatment), and whose hypertension was controlled to below 140/90 mm Hg (control). The model allowed for trends over time to be non-linear and to vary by age. Findings: the number of people aged 30-79 years with hypertension doubled from 1990 to 2019, from 331 (95% credible interval 306-359) million women and 317 (292-344) million men in 1990 to 626 (584-668) million women and 652 (604-698) million men in 2019, despite stable global age-standardised prevalence. In 2019, age-standardised hypertension prevalence was lowest in Canada and Peru for both men and women; in Taiwan, South Korea, Japan, and some countries in western Europe including Switzerland, Spain, and the UK for women; and in several low-income and middle-income countries such as Eritrea, Bangladesh, Ethiopia, and Solomon Islands for men. Hypertension prevalence surpassed 50% for women in two countries and men in nine countries, in central and eastern Europe, central Asia, Oceania, and Latin America. Globally, 59% (55-62) of women and 49% (46-52) of men with hypertension reported a previous diagnosis of hypertension in 2019, and 47% (43-51) of women and 38% (35-41) of men were treated. Control rates among people with hypertension in 2019 were 23% (20-27) for women and 18% (16-21) for men. In 2019, treatment and control rates were highest in South Korea, Canada, and Iceland (treatment >70%; control >50%), followed by the USA, Costa Rica, Germany, Portugal, and Taiwan. Treatment rates were less than 25% for women and less than 20% for men in Nepal, Indonesia, and some countries in sub-Saharan Africa and Oceania. Control rates were below 10% for women and men in these countries and for men in some countries in north Africa, central and south Asia, and eastern Europe. Treatment and control rates have improved in most countries since 1990, but we found little change in most countries in sub-Saharan Africa and Oceania. Improvements were largest in high-income countries, central Europe, and some upper-middle-income and recently high-income countries including Costa Rica, Taiwan, Kazakhstan, South Africa, Brazil, Chile, Turkey, and Iran. Interpretation Improvements in the detection, treatment, and control of hypertension have varied substantially across countries, with some middle-income countries now outperforming most high-income nations. The dual approach of reducing hypertension prevalence through primary prevention and enhancing its treatment and control is achievable not only in high-income countries but also in low-income and middle-income settings., British Heart Foundation Centre of Research Excellence Grant; World Health Organization (WHO); Abdul Latif Jameel Institute for Disease and Emergency Analytics Fellowship
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- 2021
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33. Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight
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Panda-Jonas, S. Pandey, A. Panza, F. Papandreou, D. Park, S.-W. Park, S. Parnell, W.R. Parsaeian, M. Pascanu, I.M. Pasquet, P. Patel, N.D. Pecin, I. Pednekar, M.S. Peer, N. Pei, G. Peixoto, S.V. Peltonen, M. Pereira, A.C. Peres, M.A. Pérez-Farinós, N. Pérez, C.M. Peterkova, V. Peters, A. Petersmann, A. Petkeviciene, J. Petrauskiene, A. Pettenuzzo, E. Peykari, N. Pham, S.T. Pichardo, R.N. Pierannunzio, D. Pigeot, I. Pikhart, H. Pilav, A. Pilotto, L. Pistelli, F. Pitakaka, F. Piwonska, A. Pizarro, A.N. Plans-Rubió, P. Poh, B.K. Pohlabeln, H. Pop, R.M. Popovic, S.R. Porta, M. Posch, G. Poudyal, A. Poulimeneas, D. Pouraram, H. Pourfarzi, F. Pourshams, A. Poustchi, H. Pradeepa, R. Price, A.J. Price, J.F. Providencia, R. Puder, J.J. Pudule, I. Puhakka, S.E. Puiu, M. Punab, M. Qasrawi, R.F. Qorbani, M. Bao, T.Q. Radic, I. Radisauskas, R. Rahimikazerooni, S. Rahman, M. Rahman, M. Raitakari, O. Raj, M. Rakhimova, E. Rakhmatulloev, S. Rakovac, I. Rao, S.R. Ramachandran, A. Ramke, J. Ramos, E. Ramos, R. Rampal, L. Rampal, S. Rarra, V. Rascon-Pacheco, R.A. Rasmussen, M. Rech, C.R. Redon, J. Reganit, P.F.M. Regecová, V. Revilla, L. Rezaianzadeh, A. Ribas-Barba, L. Ribeiro, R. Riboli, E. Richter, A. Rigo, F. Rinaldo, N. de Wit, T.F.R. Rito, A. Ritti-Dias, R.M. Rivera, J.A. Robitaille, C. Roccaldo, R. Rodrigues, D. Rodríguez-Artalejo, F. del Cristo Rodriguez-Perez, M. Rodríguez-Villamizar, L.A. Roggenbuck, U. Rojas-Martinez, R. Rojroongwasinkul, N. Romaguera, D. Romeo, E.L. Rosario, R.V. Rosengren, A. Rouse, I. Roy, J.G.R. Rubinstein, A. Rühli, F.J. Ruidavets, J.-B. Ruiz-Betancourt, B.S. Ruiz-Castell, M. Moreno, E.R. Rusakova, I.A. Jonsson, K.R. Russo, P. Rust, P. Rutkowski, M. Sabanayagam, C. Sacchini, E. Sachdev, H.S. Sadjadi, A. Safarpour, A.R. Safiri, S. Saki, N. Salanave, B. Martinez, E.S. Salmerón, D. Salomaa, V. Salonen, J.T. Salvetti, M. Samoutian, M. Sánchez-Abanto, J. Sans, S. Marina, L.S. Santos, D.A. Santos, I.S. Santos, L.C. Santos, M.P. Santos, O. Santos, R. 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Solfrizzi, V. Somi, M.H. Sonestedt, E. Song, Y. Sørensen, T.I.A. Sørgjerd, E.P. Jérome, C.S. Soto-Rojas, V.E. Soumaré, A. Sovic, S. Sparboe-Nilsen, B. Sparrenberger, K. Spinelli, A. Spiroski, I. Staessen, J.A. Stamm, H. Stathopoulou, M.G. Staub, K. Stavreski, B. Steene-Johannessen, J. Stehle, P. Stein, A.D. Stergiou, G.S. Stessman, J. Stevanovic, R. Stieber, J. Stöckl, D. Stocks, T. Stokwiszewski, J. Stoyanova, E. Stratton, G. Stronks, K. Strufaldi, M.W. Sturua, L. Suárez-Medina, S. Suka, M. Sun, C.-A. Sundström, J. Sung, Y.-T. Sunyer, J. Suriyawongpaisal, P. Swinburn, B.A. Sy, R.G. Syddall, H.E. Sylva, R.C. Szklo, M. Szponar, L. Tai, E.S. Tammesoo, M.-L. Tamosiunas, A. Tan, E.J. Tang, X. Tanrygulyyeva, M. Tanser, F. Tao, Y. Tarawneh, M.R. Tarp, J. Tarqui-Mamani, C.B. Braunerová, R.T. Taylor, A. Taylor, J. Tchibindat, F. Tebar, W.R. Tell, G.S. Tello, T. Tham, Y.C. Thankappan, K.R. Theobald, H. Theodoridis, X. Thijs, L. Thomas, N. Thuesen, B.H. Tichá, L. Timmermans, E.J. Tjonneland, A. 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Vlasoff, T. Vocanec, D. Vollenweider, P. Völzke, H. Voutilainen, A. Voutilainen, S. Vrijheid, M. Vrijkotte, T.G.M. Wade, A.N. Wagner, A. Waldhör, T. Walton, J. Wambiya, E.O.A. Bebakar, A.M.W. Mohamud, W.N.W. de Souza Wanderley Júnior, R. Wang, M.-D. Wang, N. Wang, Q. Wang, X. Wang, Y.X. Wang, Y.-W. Wannamethee, S.G. Wareham, N. Weber, A. Wedderkopp, N. Weerasekera, D. Weghuber, D. Wei, W. Weres, A. Werner, B. Whincup, P.H. Widhalm, K. Widyahening, I.S. Wiecek, A. Wilks, R.J. Willeit, J. Willeit, P. Williams, J. Wilsgaard, T. Wojtyniak, B. Wong-McClure, R.A. Wong, A. Wong, J.E. Wong, T.Y. Woo, J. Woodward, M. Wu, F.C. Wu, J. Wu, L.J. Wu, S. Xu, H. Xu, L. Yaacob, N.A. Yamborisut, U. Yan, W. Yang, L. Yang, X. Yang, Y. Yardim, N. Yaseri, M. Yasuharu, T. Ye, X. Yiallouros, P.K. Yoosefi, M. Yoshihara, A. You, Q.S. You, S.-L. Younger-Coleman, N.O. Yusof, S.M. Yusoff, A.F. Zaccagni, L. Zafiropulos, V. Zainuddin, A.A. Zakavi, S.R. Zamani, F. Zambon, S. Zampelas, A. Zamrazilová, H. Zapata, M.E. Zargar, A.H. Zaw, K.K. Zdrojewski, T. Zejglicova, K. Vrkic, T.Z. Zeng, Y. Zhang, L. Zhang, Z.-Y. Zhao, D. Zhao, M.-H. Zhao, W. Zhen, S. Zheng, W. Zheng, Y. Zholdin, B. Zhou, M. Zhu, D. Zins, M. Zitt, E. Zocalo, Y. Cisneros, J.Z. Zuziak, M. Ezzati, M. Filippi, S. NCD Risk Factor Collaboration (NCD-RisC)
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nutritional and metabolic diseases ,sense organs ,skin and connective tissue diseases - Abstract
From 1985 to 2016, the prevalence of underweight decreased, and that of obesity and severe obesity increased, in most regions, with significant variation in the magnitude of these changes across regions. We investigated how much change in mean body mass index (BMI) explains changes in the prevalence of underweight, obesity, and severe obesity in different regions using data from 2896 population-based studies with 187 million participants. Changes in the prevalence of underweight and total obesity, and to a lesser extent severe obesity, are largely driven by shifts in the distribution of BMI, with smaller contributions from changes in the shape of the distribution. In East and Southeast Asia and sub-Saharan Africa, the underweight tail of the BMI distribution was left behind as the distribution shifted. There is a need for policies that address all forms of malnutrition by making healthy foods accessible and affordable, while restricting unhealthy foods through fiscal and regulatory restrictions. © Copyright.
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- 2021
34. Post-exposure lopinavir-ritonavir prophylaxis versus surveillance for individuals exposed to SARS-CoV-2: the COPEP pragmatic open-label, cluster randomized trial
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Labhardt, N. D., Smit, M., Petignat, I., Perneger, T., Marinosci, A., Ustero, P., Diniz Ribeiro, M. P., Ragozzino, S., Nicoletti, G. J., Faré, P. B., Andrey, D. O., Jacquerioz, F., Lebowitz, D., Agoritsas, T., Meyer, B., Spechbach, H., Salamun, J., Guessous, I., Chappuis, F., Kaiser, L., Decosterd, L. A., Grinsztejn, B., Bernasconi, E., Cardoso, S. W., Calmy, A., and Team, Ftcs
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Article - Abstract
Background Since the beginning of the COVID-19 pandemic, no direct antiviral treatment is effective as post-exposure prophylaxis (PEP). Lopinavir/ritonavir (LPV/r) was repurposed as a potential PEP agent against COVID-19. Methods We conducted a pragmatic open-label, parallel, cluster-randomised superiority trial in four sites in Switzerland and Brazil between March 2020 to March 2021. Clusters were randomised to receive LPV/r PEP (400/100 mg) twice daily for 5 days or no PEP (surveillance). Exposure to SARS-CoV-2 was defined as a close contact of >15 minutes in
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- 2021
35. Begin with the end in mind! Use of Kirkpatrick's framework to design and implement a training programme in CPD: a practical mixed methods model for needs assessment
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Mitchell, S, Jaccard, E, Schmitz, F, Collombet, P, Cornuz, J, Waeber, G, Guessous, I, Guttormsen, S, Mitchell, S, Jaccard, E, Schmitz, F, Collombet, P, Cornuz, J, Waeber, G, Guessous, I, and Guttormsen, S
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- 2021
36. Médecine interne générale : poubelle ou poumon ? [General internal medicine: Trash or lung?]
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Cornuz, J., Guessous, I., Reny, J.L., and Vollenweider, P.
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General Practice ,Humans ,Internal Medicine - Published
- 2020
37. National trends in total cholesterol obscure heterogeneous changes in HDL and non-HDL cholesterol and total-to-HDL cholesterol ratio:a pooled analysis of 458 population-based studies in Asian and Western countries
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Taddei, C. (Cristina), Jackson, R. (Rod), Zhou, B. (Bin), Bixby, H. (Honor), Danaei, G. (Goodarz), Di Cesare, M. (Mariachiara), Kuulasmaa, K. (Kari), Hajifathalian, K. (Kaveh), Bentham, J. (James), Bennett, J. E. (James E.), Aekplakorn, W. (Wichai), Cifkova, R. (Renata), Dallongeville, J. (Jean), DeBacquer, D. (Dirk), Giampaoli, S. (Simona), Gudnason, V. (Vilmundur), Khang, Y.-H. (Young-Ho), Laatikainen, T. (Tiina), Mann, J. I. (Jim, I), Marques-Vidal, P. (Pedro), Mensah, G. A. (George A.), Mueller-Nurasyid, M. (Martina), Ninomiya, T. (Toshiharu), Petkeviciene, J. (Janina), Rodriguez-Artalejo, F. (Fernando), Servais, J. (Jennifer), Soderberg, S. (Stefan), Stavreski, B. (Bill), Wilsgaard, T. (Tom), Zdrojewski, T. (Tomasz), Zhao, D. (Dong), Stevens, G. A. (Gretchen A.), Savin, S. (Stefan), Cowan, M. J. (Melanie J.), Riley, L. M. (Leanne M.), Ezzati, M. (Majid), Adams, R. J. (Robert J.), Ahrens, W. (Wolfgang), Amouyel, P. (Philippe), Amuzu, A. (Antoinette), Anderssen, S. A. (Sigmund A.), Ariansen, I. (Inger), Arveiler, D. (Dominique), Aspelund, T. (Thor), Auvinen, J. (Juha), Avdicova, M. (Maria), Banach, M. (Maciej), Bandosz, P. (Piotr), Banegas, J. R. (Jose R.), Barbagallo, C. M. (Carlo M.), Bata, I. (Iqbal), Baur, L. A. (Louise A.), Beaglehole, R. (Robert), Bernotiene, G. (Gailute), Bi, Y. (Yufang), Bienek, A. (Asako), Bjorkelund, C. (Cecilia), Bo, S. (Simona), Boehm, B. O. (Bernhard O.), Bonaccio, M. (Marialaura), Bongard, V. (Vanina), Borchini, R. (Rossana), Borghs, H. (Herman), Breckenkamp, J. (Juergen), Brenner, H. (Hermann), Bruno, G. (Graziella), Busch, M. A. (Markus A.), Cabrera de Leon, A. (Antonio), Capuano, V. (Vincenzo), Casanueva, F. F. (Felipe F.), Casas, J.-P. (Juan-Pablo), Caserta, C. A. (Carmelo A.), Censi, L. (Laura), Chen, F. (Fangfang), Chen, S. (Shuohua), Chirlaque, M.-D. (Maria-Dolores), Cho, B. (Belong), Cho, Y. (Yumi), Chudek, J. (Jerzy), Claessens, F. (Frank), Clarke, J. (Janine), Clays, E. (Els), Cooper, C. (Cyrus), Costanzo, S. (Simona), Cottel, D. (Dominique), Cowell, C. (Chris), Crujeiras, A. B. (Ana B.), Cui, L. (Liufu), D'Arrigo, G. (Graziella), Dauchet, L. (Luc), De Backer, G. (Guy), De Bacquer, D. (Dirk), de Gaetano, G. (Giovanni), De Henauw, S. (Stefaan), De Smedt, D. (Delphine), Dennison, E. (Elaine), Deschamps, V. (Valerie), Di Castelnuovo, A. (Augusto), Dobson, A. J. (Annette J.), Donfrancesco, C. (Chiara), Doering, A. (Angela), Drygas, W. (Wojciech), Du, Y. (Yong), Dziankowska-Zaborszczyk, E. (Elzbieta), Eggertsen, R. (Robert), Ekelund, U. (Ulf), Elosua, R. (Roberto), Eriksson, J. G. (Johan G.), Evans, A. (Alun), Faeh, D. (David), Felix-Redondo, F. J. (Francisco J.), Fernandez-Berges, D. (Daniel), Ferrari, M. (Marika), Ferrieres, J. (Jean), Finn, J. D. (Joseph D.), Forslund, A.-S. (Ann-Sofie), Forsner, M. (Maria), Frontera, G. (Guillermo), Fujita, Y. (Yuki), Gaciong, Z. (Zbigniew), Galvano, F. (Fabio), Gao, J. (Jingli), Garcia-de-la-Hera, M. (Manoli), Garnett, S. P. (Sarah P.), Gaspoz, J.-M. (Jean-Michel), Gasull, M. (Magda), Gates, L. (Louise), Gianfagna, F. (Francesco), Gill, T. K. (Tiffany K.), Giovannelli, J. (Jonathan), Giwercman, A. (Aleksander), Goltzman, D. (David), Gonzalez Gross, M. (Marcela), Gottrand, F. (Frederic), Graff-Iversen, S. (Sidsel), Grafnetter, D. (Dusan), Gregor, R. D. (Ronald D.), Grodzicki, T. (Tomasz), Grosso, G. (Giuseppe), Gruden, G. (Grabriella), Gu, D. (Dongfeng), Guallar-Castillon, P. (Pilar), Gudmundsson, E. F. (Elias F.), Guessous, I. (Idris), Gunnlaugsdottir, J. (Johanna), Gutzwiller, F. (Felix), Hardy, R. (Rebecca), Hata, J. (Jun), Haugsgjerd, T. (Teresa), Hayes, A. J. (Alison J.), He, J. (Jiang), He, Y. (Yuna), Herrala, S. (Sauli), Hihtaniemi, I. T. (Ilpo Tapani), Hobbs, M. (Michael), Hopman, W. M. (Wilma M.), Maria Huerta, J. (Josi), Huybrechts, I. (Inge), Iacoviello, L. (Licia), Iannone, A. G. (Anna G.), Ikeda, N. (Nayu), Iwasaki, M. (Masanori), Jamrozik, K. (Konrad), Janszky, I. (Imre), Jarvelin, M.-R. (Marjo-Riitta), Jasienska, G. (Grazyna), Jennings, G. (Garry), Jeong, S.-L. (Seung-Lyeal), Jiang, C. Q. (Chao Qiang), Joffres, M. (Michel), Jokelainen, J. J. (Jari J.), Jonas, J. B. (Jost B.), Jozwiak, J. (Jacek), Kajantie, E. O. (Eero O.), Kauhanen, J. (Jussi), Keil, U. (Ulrich), Keinanen-Kiukaanniemi, S. (Sirkka), Kersting, M. (Mathilde), Kiechl-Kohlendorfer, U. (Ursula), Kiechl, S. (Stefan), Kim, J. (Jeongseon), Kim, Y.-Y. (Yeon-Yong), Klumbiene, J. (Jurate), Knoflach, M. (Michael), Ko, S. (Stephanie), Kolle, E. (Elin), Korpelainen, R. (Raija), Koskinen, S. (Seppo), Kouda, K. (Katsuyasu), Kratzer, W. (Wolfgang), Kriemler, S. (Susi), Krokstad, S. (Steinar), Kujala, U. M. (Urho M.), Kurjata, P. (Pawel), Lam, T. H. (Tai Hing), Lanska, V. (Vera), Lappas, G. (Georg), Laugsand, L. E. (Lars E.), Lee, J. (Jeonghee), Lehtimaki, T. (Terho), Li, Y. (Yanping), Lilly, C. L. (Christa L.), Lin, X. (Xu), Lind, L. (Lars), Lissner, L. (Lauren), Liu, J. (Jing), Lopez-Garcia, E. (Esther), Lorbeer, R. (Roberto), Eugenio Lozano, J. (Jose), Luksiene, D. (Dalia), Lundqvist, A. (Annamari), Lundqvist, R. (Robert), Lytsy, P. (Per), Ma, G. (Guansheng), Machi, S. (Suka), Maggi, S. (Stefania), Magliano, D. J. (Dianna J.), Manzato, E. (Enzo), Mathiesen, E. B. (Ellisiv B.), McLachlan, S. (Stela), McLean, R. M. (Rachael M.), McLean, S. B. (Scott B.), Meirhaeghe, A. (Aline), Meisinger, C. (Christa), Metcalf, P. (Patricia), Mi, J. (Jie), Miller, J. C. (Jody C.), Moreno, L. A. (Luis A.), Morin, S. N. (Suzanne N.), Mossakowska, M. (Malgorzata), Muiesan, M. L. (Maria L.), Mursu, J. (Jaakko), Nakamura, H. (Harunobu), Namesna, J. (Jana), Nauck, M. (Matthias), Maria Navarrete-Munoz, E. (Eva), Neal, W. A. (William A.), Nenko, I. (Ilona), Niiranen, T. J. (Teemu J.), Ning, G. (Guang), Noale, M. (Marianna), Norie, S. (Sawada), Noto, D. (Davide), O'Neill, T. (Terence), O'Reilly, D. (Dermot), Oh, K. (Kyungwon), Olafsson, O. (Orn), Paccaud, F. M. (Fred Michel), Pajak, A. (Andrzej), Palmieri, L. (Luigi), Panza, F. (Francesco), Parnell, W. R. (Winsome R.), Peltonen, M. (Markku), Peters, A. (Annette), Petersmann, A. (Astrid), Pigeot, I. (Iris), Pilotto, L. (Lorenza), Piwonska, A. (Aleksandra), Plans-Rubio, P. (Pedro), Porta, M. (Miquel), Price, J. F. (Jacqueline F.), Puder, J. J. (Jardena J.), Puhakka, S. E. (Soile E.), Radisauskas, R. (Ricardas), Raitakari, O. (Olli), Ramos, R. (Rafel), Redon, J. (Josep), Rigo, F. (Fernando), del Cristo Rodriguez-Perez, M. (Maria), Romaguera, D. (Dora), Ronkainen, K. (Kimmo), Rosengren, A. (Annika), Roy, J. G. (Joel G. R.), Ruidavets, J.-B. (Jean-Bernard), Rutkowski, M. (Marcin), Salanave, B. (Benoit), Salmeron, D. (Diego), Salomaa, V. (Veikko), Salonen, J. T. (Jukka T.), Salvetti, M. (Massimo), Sans, S. (Susana), Saramies, J. L. (Jouko L.), Saum, K.-U. (Kai-Uwe), Scheidt-Nave, C. (Christa), Schienkiewitz, A. (Anja), Schipf, S. (Sabine), Schmidt, C. O. (Carsten O.), Schoettker, B. (Ben), Sebert, S. (Sylvain), Sen, A. (Abhijit), Shaw, J. E. (Jonathan E.), Shibuya, K. (Kenji), Shin, D. W. (Dong Wook), Shiri, R. (Rahman), Simons, J. (Judith), Simons, L. A. (Leon A.), Sjostrom, M. (Michael), Slowikowska-Hilczer, J. (Jolanta), Slusarczyk, P. (Przemyslaw), Solfrizzi, V. (Vincenzo), Sonestedt, E. (Emily), Soumare, A. (Aicha), Staessen, J. A. (Jan A.), Stathopoulou, M. G. (Maria G.), Steene-Johannessen, J. (Jostein), Stehle, P. (Peter), Stieber, J. (Jutta), Stoeckl, D. (Doris), Stokwiszewski, J. (Jakub), Sundstrom, J. (Johan), Suriyawongpaisal, P. (Paibul), Tamosiunas, A. (Abdonas), Tan, E. J. (Eng Joo), Taylor, A. (Anne), Tell, G. (Grethe), Thijs, L. (Lutgarde), Tolonen, H. K. (Hanna K.), Topor-Madry, R. (Roman), Jose Tormo, M. (Maria), Torrent, M. (Maties), Tsugane, S. (Shoichiro), Tuomainen, T.-P. (Tomi-Pekka), Tuomilehto, J. (Jaakko), Tzourio, C. (Christophe), Uusitalo, H. M. (Hannu M. T.), Van Herck, K. (Koen), Vanderschueren, D. (Dirk), Vanuzzo, D. (Diego), Vatten, L. (Lars), Vega, T. (Tomas), Veronesi, G. (Giovanni), Vioque, J. (Jesus), Virtanen, J. K. (Jyrki K.), Visvikis-Siest, S. (Sophie), Vollenweider, P. (Peter), Voutilainen, S. (Sari), Vrijheid, M. (Martine), Wagner, A. (Aline), Wagner, A. (Anne), Wang, M.-D. (Ming-Dong), Wang, Q. (Qian), Wang, Y. X. (Ya Xing), Wannamethee, S. G. (S. Goya), Wei, W. (Wenbin), Whincup, P. H. (Peter H.), Wiecek, A. (Andrzej), Willeit, J. (Johann), Willeit, P. (Peter), Wojtyniak, B. (Bogdan), Wong, A. (Andrew), Woodward, M. (Mark), Wu, F. C. (Frederick C.), Wu, S. (Shouling), Xu, H. (Haiquan), Xu, L. (Liang), Yan, W. (Weili), Yang, X. (Xiaoguang), Ye, X. (Xingwang), Yoshihara, A. (Akihiro), Zambon, S. (Sabina), and Zhao, W. (Wenhua)
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blood lipids ,HDL cholesterol ,LDL cholesterol ,total cholesterol ,nutritional and metabolic diseases ,lipids (amino acids, peptides, and proteins) ,multi-country study - Abstract
Background: Although high-density lipoprotein (HDL) and non-HDL cholesterol have opposite associations with coronary heart disease, multi-country reports of lipid trends only use total cholesterol (TC). Our aim was to compare trends in total, HDL and non-HDL cholesterol and the total-to-HDL cholesterol ratio in Asian and Western countries. Methods: We pooled 458 population-based studies with 82.1 million participants in 23 Asian and Western countries. We estimated changes in mean total, HDL and non-HDL cholesterol and mean total-to-HDL cholesterol ratio by country, sex and age group. Results: Since ∼1980, mean TC increased in Asian countries. In Japan and South Korea, the TC rise was due to rising HDL cholesterol, which increased by up to 0.17 mmol/L per decade in Japanese women; in China, it was due to rising non-HDL cholesterol. TC declined in Western countries, except in Polish men. The decline was largest in Finland and Norway, at ∼0.4 mmol/L per decade. The decline in TC in most Western countries was the net effect of an increase in HDL cholesterol and a decline in non-HDL cholesterol, with the HDL cholesterol increase largest in New Zealand and Switzerland. Mean total-to-HDL cholesterol ratio declined in Japan, South Korea and most Western countries, by as much as ∼0.7 per decade in Swiss men (equivalent to ∼26% decline in coronary heart disease risk per decade). The ratio increased in China. Conclusions: HDL cholesterol has risen and the total-to-HDL cholesterol ratio has declined in many Western countries, Japan and South Korea, with only a weak correlation with changes in TC or non-HDL cholesterol.
- Published
- 2020
38. Repositioning of the global epicentre of non-optimal cholesterol
- Author
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Taddei, C. (Cristina), Zhou, B. (Bin), Bixby, H. (Honor), Carrillo-Larco, R.M. (Rodrigo M.), Danaei, G. (Goodarz), Jackson, R.T. (Rod T.), Farzadfar, F. (Farshad), Sophiea, M.K. (Marisa K.), Di Cesare, M. (Mariachiara), Iurilli, M.L.C. (Maria Laura Caminia), Martinez, A.R. (Andrea Rodriguez), Asghari, G. (Golaleh), Dhana, K. (Klodian), Gulayin, P. (Pablo), Kakarmath, S. (Sujay), Santero, M. (Marilina), Voortman, R.G. (Trudy), Riley, L.M. (Leanne M.), Cowan, M.J. (Melanie J.), Savin, S. (Stefan), Bennett, J.E. (James E.), Stevens, G.A. (Gretchen A.), Paciorek, C.J. (Christopher J.), Aekplakorn, W. (Wichai), Cifkova, R. (Renata), Giampaoli, S. (Simona), Kengne, A.P. (Andre Pascal), Khang, Y.-H. (Young-Ho), Kuulasmaa, K. (Kari), Laxmaiah, A. (Avula), Margozzini, P. (Paula), Mathur, P. (Prashant), Nordestgaard, B.G. (Børge), Zhao, D. (Dong), Aadahl, M. (Mette), Abarca-Gómez, L. (Leandra), Rahim, H.A. (Hanan Abdul), Abu-Rmeileh, N.M. (Niveen M.), Acosta-Cazares, B. (Benjamin), Adams, R.J. (Robert J.), Agdeppa, I.A. (Imelda A.), Aghazadeh-Attari, J. (Javad), Aguilar-Salinas, C.A. (Carlos A.), Agyemang, C.O. (Charles), Ahluwalia, T.S. (Tarunveer Singh), Ahmad, N.A. (Noor Ani), Ahmadi, A. (Ali), Ahmadi, N. (Naser), Ahmed, S.H. (Soheir H.), Ahrens, W. (W.), Ajlouni, K. (Kamel), Alarouj, M. (Monira), AlBuhairan, F. (Fadia), AlDhukair, S. (Shahla), Ali, M.M. (Mohamed M.), Alkandari, A. (Abdullah), Alkerwi, A. (Ala’a), Aly, E. (Eman), Amarapurkar, D.N. (Deepak N.), Amouyel, P. (Philippe), Andersen, L.B. (Lars Bo), Anderssen, S.A. (Sigmund A.), Anjana, R.M. (Ranjit Mohan), Ansari-Moghaddam, A. (Alireza), Aounallah-Skhiri, H. (Hajer), Araújo, J. (Joana), Ariansen, I. (Inger), Aris, T. (Tahir), Arku, R.E. (Raphael E.), Arlappa, N. (Nimmathota), Aryal, K.K. (Krishna K.), Aspelund, T. (Thor), Assunção, M.C.F. (Maria Cecília F.), Auvinen, J. (Juha), Avdicová, M. (Mária), Azevedo, A. (Ana), Azizi, J. (Joshan), Azmin, M. (Mehrdad), Balakrishna, N. (Nagalla), Bamoshmoosh, M. (Mohamed), Banach, M. (Maciej), Bandosz, P. (Piotr), Banegas, J.R. (José R.), Barbagallo, C.M. (Carlo M.), Barceló, A. (Alberto), Barkat, A. (Amina), Bata, I. (Iqbal), Batieha, A.M. (Anwar M.), Batyrbek, A. (Assembekov), Baur, L.A. (Louise A.), Beaglehole, R. (Robert), Belavendra, A. (Antonisamy), Ben Romdhane, H. (Habiba), Benet, M. (Mikhail), Benn, M. (Marianne), Berkinbayev, S. (Salim), Bernabe-Ortiz, A. (Antonio), Bernotiene, G. (Gailute), Bettiol, H. (Heloisa), Bhargava, S.K. (Santosh K.), Bi, Y. (Yufang), Bienek, A. (Asako), Bikbov, M. (Mukharram), Bista, B. (Bihungum), Bjerregaard, P. (Peter), Bjertness, E. (Espen), Bjertness, M.B. (Marius B.), Björkelund, C. (Cecilia), Bloch, K.V. (Katia V.), Blokstra, A. (Anneke), Bo, S. (Simona), Boehm, B.O. (Bernhard O.), Boggia, J.G. (Jose G.), Boissonnet, C.P. (Carlos P.), Bonaccio, M. (Marialaura), Bongard, V. (Vanina), Borchini, R. (Rossana), Borghs, H. (Herman), Bovet, P. (Pascal), Brajkovich, I. (Imperia), Breckenkamp, J. (Juergen), Brenner, H. (Hermann), Brewster, L.M. (Lizzy), Bruno, G. (Graziella), Bugge, A. (Anna), Busch, M.A. (Markus A.), de León, A.C. (Antonio Cabrera), Cacciottolo, J. (Joseph), Can, G. (Günay), Cândido, A.P.C. (Ana Paula C.), Capanzana, M.V. (Mario V.), Capuano, E. (Eduardo), Capuano, V. (Vincenzo), Cardoso, V.C. (Viviane C.), Carvalho, J. (Joana), Casanueva, F.F., Censi, L. (Laura), Chadjigeorgiou, C.A. (Charalambos A.), Chamukuttan, S. (Snehalatha), Chaturvedi, N. (Nish), Chen, C.-J. (Chien-Jen), Chen, F. (Fangfang), Chen, S. (Shuohua), Cheng, C.-Y. (Ching-Yu), Cheraghian, B. (Bahman), Chetrit, A. (Angela), Chiou, S.-T. (Shu-Ti), Chirlaque, M.D. (M.), Cho, B. (Belong), Cho, Y. (Yumi), Chudek, J. (Jerzy), Claessens, F. (Frank), Clarke, J. (Janine), Clays, E. (Els), Concin, H. (Hans), Confortin, S.C. (Susana C.), Cooper, C. (Charles), Costanzo, S. (Simona), Cottel, D. (Dominique), Cowell, C. (Chris), Crujeiras, A.B. (Ana B.), Csilla, S. (Semánová), Cui, L. (Liufu), Cureau, F.V. (Felipe V.), D’Arrigo, G. (Graziella), d’Orsi, E. (Eleonora), Dallongeville, J., Damasceno, A. (Albertino), Dankner, R. (Rachel), Dantoft, T.M. (Thomas M.), Dauchet, L. (Luc), Davletov, K. (Kairat), Backer, G. (Guy) de, Bacquer, D. (Dirk) de, de Gaetano, G. (Giovanni), De Henauw, S. (Stefaan), de Oliveira, P.D. (Paula Duarte), De Ridder, D. (David), De Smedt, D. (Delphine), Deepa, M. (Mohan), Deev, A.D. (Alexander D.), Dehghan, A. (Abbas), Delisle, H. (Hélène), Dennison, E.M. (Elaine), Deschamps, V. (Valérie), Dhimal, M. (Meghnath), Di Castelnuovo, A.F. (Augusto F.), Dika, Z. (Zivka), Djalalinia, S. (Shirin), Dobson, A.J. (Annette J.), Donfrancesco, C. (Chiara), Donoso, S.P. (Silvana P.), Döring, A. (Angela), Dorobantu, M. (Maria), Dragano, N. (Nico), Drygas, W. (Wojciech), Du, Y. (Yong), Duante, C.A. (Charmaine A.), Duda, R.B. (Rosemary B.), Dzerve, V. (Vilnis), Dziankowska-Zaborszczyk, E. (Elzbieta), Eddie, R. (Ricky), Eftekhar, E. (Ebrahim), Eggertsen, R. (Robert), Eghtesad, S. (Sareh), Eiben, G. (Gabriele), Ekelund, U. (Ulf), El Ati, J. (Jalila), Eldemire-Shearer, D. (Denise), Eliasen, M. (Marie), Elosua, R. (Roberto), Erasmus, R.T. (Rajiv T.), Erbel, R. (Raimund), Erem, C. (Cihangir), Eriksen, L. (Louise), Hagen, K. (Knut), Escobedo-de la Peña, J. (Jorge), Eslami, S. (Saeid), Esmaeili, A. (Ali), Evans, A. (Alun), Faeh, D. (David), Fall, C.H. (Caroline H.), Faramarzi, E. (Elnaz), Farjam, M. (Mojtaba), Fattahi, M.R. (Mohammad Reza), Felix-Redondo, F.J. (Francisco J.), Ferguson, T.S. (Trevor S.), Fernández-Bergés, D. (Daniel), Ferrante, D. (Daniel), Ferrari, M. (Marika), Ferreccio, C. (Catterina), Ferrieres, J. (Jean), Föger, B. (Bernhard), Foo, L.H. (Leng Huat), Forslund, A.-S. (Ann-Sofie), Forsner, M. (Maria), Fouad, H.M. (Heba M.), Francis, D.K. (Damian K.), do Carmo Franco, M. (Maria), Franco, O.H. (Oscar H.), Frontera, G. (Guillermo), Fujita, Y. (Yuki), Fumihiko, M. (Matsuda), Furusawa, T. (Takuro), Gaciong, Z. (Zbigniew), Galvano, F. (Fabio), Gao, J. (Jingli), Garcia-de-la-Hera, M. (Manoli), Garnett, S.P. (Sarah P.), Gaspoz, J.-M. (Jean-Michel), Gasull, M. (Magda), Gazzinelli, A. (Andrea), Geleijnse, J.M. (Marianne), Ghanbari, A. (Ali), Ghasemi, E. (Erfan), Gheorghe-Fronea, O.-F. (Oana-Florentina), Ghimire, A. (Anup), Gianfagna, F. (Francesco), Gill, T.K. (Tiffany K.), Giovannelli, J. (Jonathan), Gironella, G. (Glen), Giwercman, A. (Aleksander), Goltzman, D. (David), Gonçalves, H. (Helen), Gonzalez-Chica, D.A. (David A.), Gonzalez-Gross, M. (Marcela), González-Rivas, J.P. (Juan P.), González-Villalpando, C. (Clicerio), González-Villalpando, M.E. (María Elena), Gonzalez, A.R. (Angel R.), Gottrand, F., Graff-Iversen, S. (Sidsel), Grafnetter, D. (Dušan), Gregor, R.D. (Ronald D.), Grodzicki, T. (Tomasz), Grøntved, A. (Anders), Grosso, G. (Giuseppe), Gruden, G. (Gabriella), Gu, D. (Dongfeng), Guallar-castillón, P. (Pilar), Guan, O.P. (Ong Peng), Gudmundsson, E.F. (Elias F.), Gudnason, V. (Vilmundur), Guerrero, R. (Ramiro), Guessous, I. (Idris), Gunnlaugsdottir, J. (Johanna), Gupta, R. (Rajeev), Gutierrez, L. (Laura), Gutzwiller, F. (Felix), Ha, S. (Seongjun), Hadaegh, F. (Farzad), Haghshenas, R. (Rosa), Hakimi, H. (Hamid), Hambleton, I.R. (Ian R.), Hamzeh, B. (Behrooz), Hantunen, S. (Sari), Kumar, R.H. (Rachakulla Hari), Hashemi-Shahri, S.M. (Seyed Mohammad), Hata, J. (Jun), Haugsgjerd, T. (Teresa), Hayes, A.J. (Alison J.), He, J. (Jiang), He, Y. (Yong), Hendriks, M.E. (Marleen), Henriques, A. (Ana), Herrala, S. (Sauli), Heshmat, R. (Ramin), Hill, A.G. (Allan G.), Ho, S.Y. (Sai Yin), Ho, S.C. (Suzanne C.), Hobbs, M. (Michael), Hofman, A. (Albert), Homayounfar, R. (Reza), Hopman, W.M. (Wilma M.), Horimoto, A.R.V.R. (Andrea R. V. R.), Hormiga, C.M. (Claudia M.), Horta, B.L. (Bernardo L.), Houti, L. (Leila), Howitt, C. (Christina), Htay, T.T. (Thein Thein), Htet, A.S. (Aung Soe), Htike, M.M.T. (Maung Maung Than), Huerta, J.M. (José María), Huhtaniemi, I.T. (I.), Huisman, M. (Martijn), Hunsberger, M.L. (Monica L.), Husseini, A. (Abdullatif), Huybrechts, I. (Inge), Hwalla, N. (Nahla), Iacoviello, L. (Licia), Iannone, A.G. (Anna G.), Ibrahim, M.M. (Mohsen), Wong, N.I. (Norazizah Ibrahim), Iglesia, I. (Iris), Ikeda, N. (Nayu), Ikram, M.A. (Arfan), Iotova, V. (Violeta), Irazola, V.E. (Vilma E.), Ishida, T. (Takafumi), Islam, M. (Muhammad), al-Safi Ismail, A. (Aziz), Iwasaki, M. (Masanori), Jacobs, J.M. (Jeremy M.), Jaddou, H.Y. (Hashem Y.), Jafar, T.H. (Tazeen), James, K. (Kenneth), Jamrozik, K., Janszky, I. (Imre), Janus, E. (Edward), Jarvelin, M.-R. (Marjo-Riitta), Jasienska, G. (Grazyna), Jelakovic, A. (Ana), Jelakovic, B. (Bojan), Jennings, G. (Garry), Jensen, G.B. (Gorm), Jeong, S.-L. (Seung-lyeal), Jha, A.K. (Anjani Kumar), Jiang, C.Q. (Chao Qiang), Jimenez, R.O. (Ramon O.), JöCkel, K.-H. (Karl-Heinz), Joffres, M. (Michel), Jokelainen, J.J. (Jari J.), Jonas, J.B. (Jost B.), Jorgensen, T. (Torben), Joshi, P. (Pradeep), Joukar, F. (Farahnaz), Józwiak, J. (Jacek), Juolevi, A. (Anne), Kafatos, A. (Anthony), Kajantie, E. (Eero), Kalter-Leibovici, O. (Ofra), Kamaruddin, N.A. (Nor Azmi), Kamstrup, P.R. (Pia R.), Karki, K.B. (Khem B.), Katz, J. (Joanne), Kauhanen, J. (Jussi), Kaur, P. (Prabhdeep), Kavousi, M. (Maryam), Kazakbaeva, G. (Gyulli), Keil, M. (Mark), Keinanen-Kiukaanniemi, S. (Sirkka), Kelishadi, R. (Roya), Keramati, M. (Maryam), Kerimkulova, A. (Alina), Kersting, M. (Mathilde), Khader, Y.S. (Yousef Saleh), Khalili, D. (Davood), Khateeb, M. (Mohammad), Kheradmand, M. (Motahareh), Khosravi, A. (Alireza), Kiechl-Kohlendorfer, U. (Ursula), Kiechl, S. (Stefan), Killewo, J. (Japhet), Kim, H.C. (Hyeon Chang), Kim, J. (Jeongseon), Kim, Y.-Y. (Yeon-Yong), Klumbiene, J. (Jurate), Knoflach, M. (Michael), Ko, S. (Stephanie), Kohler, H.-P. (Hans-Peter), Kohler, I.V. (Iliana V.), Kolle, E. (Elin), Kolsteren, P. (Patrick), König, J. (Jürgen), Korpelainen, R. (Raija), Korrovits, P. (Paul), Kos, J. (Jelena), Koskinen, S. (Seppo), Kouda, K. (Katsuyasu), Kowlessur, S. (Sudhir), Kratzer, W. (Wolfgang), Kriemler, S. (Susi), Kristensen, P.L. (Peter Lund), Krokstad, S. (Steiner), Kromhout, D. (Daan), Kujala, U.M. (Urho), Kurjata, P. (Pawel), Kyobutungi, C. (Catherine), Laamiri, F.Z. (Fatima Zahra), Laatikainen, T. (Tiina), Lachat, C. (Carl), Laid, Y. (Youcef), Lam, T.H. (Tai Hing), Lambrinou, C.-P. (Christina-Paulina), Lanska, V. (Vera), Lappas, G. (Georg), Larijani, B. (Bagher), Latt, T.S. (Tint Swe), Laugsand, L.E. (Lars E.), Lazo-Porras, M. (Maria), Lee, J. (Jeannette), Lee, J. (Jeonghee), Lehmann, N. (Nils), Lehtimäki, T. (Terho), Levitt, N.S. (Naomi S.), Li, Y. (Yanping), Lilly, C.L. (Christa L.), Lim, W.-Y. (Wei-Yen), Lima-Costa, M.F. (Maria Fernanda), Lin, H.-H. (Hsien-Ho), Lin, X. (Xu), Lin, Y.-T. (Yi-Ting), Kao, W.H.L. (Wen), Linneberg, A. (Allan), Lissner, L. (Lauren), Liu, J. (Jing), Loit, H.-M. (Helle-Mai), Lopez-Garcia, E. (Esther), Lopez, T. (Tania), Lotufo, P.A. (Paulo A), Lozano, J.E. (José Eugenio), Luksiene, D. (Dalia), Lundqvist, A. (Annamari), Lundqvist, R. (Robert), Lunet, N. (Nuno), Ma, G. (Guansheng), Machado-Coelho, G.L.L. (George L. L.), Machado-Rodrigues, A.M. (Aristides M.), Machi, S. (Suka), Madar, A.A. (Ahmed A.), Maggi, S. (Stefania), Magliano, D.J., Magriplis, E. (Emmanuella), Mahasampath, G. (Gowri), Maire, B. (Bernard), Makdisse, M. (Marcia), Malekzadeh, F. (Fatemeh), Malekzadeh, R. (Reza), Rao, K.M. (Kodavanti Mallikharjuna), Manios, Y., Mann, J.I. (Jim I.), Mansour-Ghanaei, F. (Fariborz), Manzato, E. (Enzo), Marques-Vidal, P. (Pedro), Martorell, R. (Reynaldo), Mascarenhas, L.P. (Luis P.), Mathiesen, E.B. (Ellisiv), Matsha, T.E. (Tandi E.), Mavrogianni, C. (Christina), McFarlane, S.R. (Shelly R.), McGarvey, S.T. (Stephen T.), McLachlan, S. (Stela), McLean, R.M. (Rachael M.), McLean, S.B. (Scott B.), McNulty, B.A. (Breige A.), Mediene-Benchekor, S. (Sounnia), Mehdipour, P. (Parinaz), Mehlig, K. (Kirsten), Mehrparvar, A.H. (Amir Houshang), Meirhaeghe, A. (Aline), Meisinger, C. (Christa), Menezes, A.M.B. (Ana M.B.), Menon, G.R. (Geetha R.), Merat, S. (Shahin), Mereke, A. (Alibek), Meshram, I.I. (Indrapal I.), Metcalf, P. (Patricia), Meyer, H.E. (Haakon E.), Mi, J. (Jie), Michels, N. (Nathalie), Miller, J.C. (Jody C.), Minderico, C.S. (Cláudia S.), Mini, G.K. (G. K.), Miquel, J.F. (Juan Francisco), Miranda, J.J. (J. Jaime), Mirjalili, M.R. (Mohammad Reza), Mirrakhimov, E. (Erkin), Modesti, P.A. (Pietro A.), Moghaddam, S.S. (Sahar Saeedi), Mohajer, B. (Bahram), Mohamed, M.K. (Mostafa K.), Mohammad, K. (Kazem), Mohammadi, Z. (Zahra), Mohammadifard, N. (Noushin), Mohammadpourhodki, R. (Reza), Mohan, V. (Viswanathan), Mohanna, S. (Salim), Yusoff, M.F.M. (Muhammad Fadhli Mohd), Mohebbi, I. (Iraj), Mohebi, F. (Farnam), Moitry, M. (Marie), Møllehave, L.T. (Line T.), Møller, N.C. (Niels C.), Molnár, D. (Dénes), Momenan, A. (Amirabbas), Mondo, C.K. (Charles K.), Monterrubio-Flores, E. (Eric), Moosazadeh, M. (Mahmood), Morejon, A. (Alain), Moreno, L. (Luis), Morgan, K. (Karen), Morin, S.N. (Suzanne N.), Moschonis, G. (George), Mossakowska, M. (Malgorzata), Mostafa, A. (Aya), Mota, J. (Jorge), Motlagh, M.E. (Mohammad Esmaeel), Motta, J. (Jorge), Msyamboza, K.P. (Kelias P.), Muiesan, M.L. (Maria Lorenza), Müller-Nurasyid, M. (Martina), Mursu, J. (Jaakko), Mustafa, N. (Norlaila), Nabipour, I. (Iraj), Naderimagham, S. (Shohreh), Nagel, G. (Gabriele), Naidu, B.M. (Balkish M.), Najafi, F. (Farid), Nakamura, H. (Harunobu), Námešná, J. (Jana), Nang, E.E.K. (Ei Ei K.), Nangia, V.B. (Vinay B.), Nauck, M. (Matthias), Neal, W.A. (William A.), Nejatizadeh, A. (Azim), Nenko, I. (Ilona), Nervi, F. (Flavio), Nguyen, N.D. (Nguyen D.), Nguyen, Q.N. (Quang Ngoc), Nieto-Martínez, R.E. (Ramfis E.), Nihal, T. (Thomas), Niiranen, T.J. (Teemu J.), Ning, G. (Guang), Ninomiya, T. (Toshiharu), Noale, M. (Marianna), Noboa, O.A. (Oscar A.), Noto, D. (Davide), Nsour, M.A. (Mohannad Al), Nuhoğlu, I. (Irfan), O’Neill, T.W. (Terence W.), O’Reilly, D. (Dermot), Ochoa-Avilés, A.M. (Angélica M.), Oh, K. (Kyungwon), Ohtsuka, R. (Ryutaro), Olafsson, Ö. (Örn), Olié, V. (Valérie), Oliveira, I.O. (Isabel O.), Omar, M.A. (Mohd Azahadi), Onat, A. (Altan), Ong, S.K. (Sok King), Ordunez, P. (Pedro), Ornelas, R. (Rui), Ortiz, P.J. (Pedro J.), Osmond, C. (Clive), Ostojic, S.M. (Sergej M.), Ostovar, A. (Afshin), Otero, J.A. (Johanna A.), Owusu-Dabo, E. (Ellis), Paccaud, F.M. (Fred Michel), Pahomova, E. (Elena), Pajak, A. (Andrzej), Palmieri, L. (Luigi), Pan, W.-H. (Wen-Harn), Panda-Jonas, S. (Songhomitra), Panza, F. (Francesco), Parnell, W.R. (Winsome R.), Patel, N.D. (Nikhil D.), Peer, N. (Nasheeta), Peixoto, S.V. (Sergio Viana), Peltonen, M. (Markku), Pereira, A. (A.), Peters, A. (Annette), Petersmann, A. (Astrid), Petkeviciene, J. (Janina), Peykari, N. (Niloofar), Pham, S.T. (Son Thai), Pichardo, R.N. (Rafael N.), Pigeot, I. (Iris), Pilav, A. (Aida), Pilotto, A. (Alberto), Piwonska, A. (Aleksandra), Pizarro, A.N. (Andreia N.), Plans-Rubió, P. (Pedro), Plata, S. (Silvia), Pohlabeln, H. (Hermann), Porta, M. (Miquel), Portegies, M.L.P. (Marileen), Poudyal, A. (Anil), Pourfarzi, F. (Farhad), Poustchi, H. (Hossein), Pradeepa, R. (Rajendra), Price, J.F. (Jacqueline F.), Providencia, R. (Rui), Puder, J.J. (Jardena J.), Puhakka, S.E. (Soile E.), Punab, M. (Margus), Qorbani, M. (Mostafa), Bao, T.Q. (Tran Quoc), Radisauskas, R. (Ricardas), Rahimikazerooni, S. (Salar), Raitakari, O. (Olli), Rao, S.R. (Sudha Ramachandra), Ramachandran, A. (Ambady), Ramos, E. (Elisabete), Ramos, R. (Rafel), Rampal, L. (Lekhraj), Rampal, S. (Sanjay), Redón, J. (Josep), Reganit, P.F.M. (Paul Ferdinand M.), Revilla, L. (Luis), Rezaianzadeh, A. (Abbas), Ribeiro, R. (Robespierre), Richter, A. (Adrian), Rigo, F. (Fernando), Rinke de Wit, T.F. (Tobias), Rodríguez Artalejo, F. (Fernando), del Cristo Rodriguez-Perez, M. (María), Rodríguez-Villamizar, L.A. (Laura A.), Roggenbuck, U. (Ulla), Rojas-Martinez, R. (Rosalba), Romaguera, D. (Dora), Romeo, E.L. (Elisabetta L.), Rosengren, A. (Annika), Roy, J.G.R. (Joel G. R.), Rubinstein, A. (Adolfo), Ruidavets, J.-B. (Jean-Bernard), Ruiz-Betancourt, B.S. (Blanca Sandra), Russo, P. (Paola), Rust, P. (Petra), Rutkowski, M. (Marcin), Sabanayagam, C. (Charumathi), Sachdev, H.S. (Harshpal S.), Sadjadi, A. (Alireza), Safarpour, A.R. (Ali Reza), Safiri, S. (Saeid), Saidi, O. (Olfa), Saki, N. (Nader), Salanave, B. (Benoit), Salmerón, D. (Diego), Salomaa, V. (Veikko), Salonen, J.T. (Jukka T.), Salvetti, M. (Massimo), Sánchez-Abanto, J. (Jose), Sans, S. (Susana), Santaliestra-Pasías, A.M. (Alba M.), Santos, D.A. (Diana A.), Santos, M.P. (Maria Paula), Santos, R. (Rute), Saramies, J.L. (Jouko L.), Sardinha, L.B. (Luis B.), Sarrafzadegan, N. (Nizal), Saum, K.-U. (Kai-Uwe), Savva, S., Sawada, N. (Norie), Sbaraini, M. (Mariana), Scazufca, M. (Marcia), Schaan, B.D. (Beatriz D.), Schargrodsky, H. (Herman), Scheidt-Nave, C. (C.), Schienkiewitz, A. (Anja), Schipf, S. (Sabine), Schmidt, C.O. (Carsten O.), Schöttker, B. (Ben), Schramm, S. (Sara), Sebert, S. (Sylvain), Sein, A.A. (Aye Aye), Sen, A. (Abhijit), Sepanlou, S.G. (Sadaf G), Servais, J. (Jennifer), Shakeri, R. (Ramin), Shalnova, S.A. (Svetlana A.), Shamah-Levy, T. (Teresa), Sharafkhah, M. (Maryam), Sharma, S.K. (Sanjib K.), Shaw, J.E., Shayanrad, A. (Amaneh), Shi, Z. (Zumin), Shibuya, K. (Kenji), Shimizu-Furusawa, H. (Hana), Shin, D.W. (Dong Wook), Shin, Y. (Youchan), Shirani, M. (Majid), Shiri, R. (Rahman), Shrestha, N. (Namuna), Si-Ramlee, K. (Khairil), Siani, A. (Alfonso), Siantar, R. (Rosalynn), Sibai, A.M. (Abla M.), Silva, D.A.S. (Diego Augusto Santos), Simon, M. (Mary), Simons, J. (Judith), Simons, L.A. (Leon A.), Sjöström, M. (Michael), Skaaby, T. (Tea), Slowikowska-Hilczer, J. (Jolanta), Slusarczyk, P. (Przemyslaw), Smeeth, L. (Liam), Snijder, M.B. (Marieke), Söderberg, S. (Stefan), Soemantri, A. (Augustinus), Sofat, R. (Reecha), Solfrizzi, V. (Vincenzo), Somi, M.H. (Mohammad Hossein), Sonestedt, E. (Emily), Sørensen, T.I.A. (Thorkild), Jérome, C.S. (Charles Sossa), Soumaré, A. (Aicha), Sozmen, K. (Kaan), Sparrenberger, K. (Karen), Staessen, J.A. (Jan), Stathopoulou, M.G. (Maria G), Stavreski, B. (Bill), Steene-Johannessen, J. (Jostein), Stehle, P. (Peter), Stein, A.D. (Aryeh D.), Stessman, J. (Jochanan), Stevanović, R. (Ranko), Stieber, J. (Jutta), Stöckl, D. (Doris), Stokwiszewski, J. (Jakub), Stronks, K. (Karien), Strufaldi, M.W. (Maria Wany), Suárez-Medina, R. (Ramón), Sun, C.-A. (Chien-An), Sundström, J. (Johan), Suriyawongpaisal, P. (Paibul), Sy, R.G. (Rody G.), Sylva, R.C. (René Charles), Szklo, M. (Moyses), Tai, E.S. (Shyong), Tamosiunas, A. (Abdonas), Tan, E.J. (Eng Joo), Tarawneh, M.R. (Mohammed Rasoul), Tarqui-Mamani, C.B. (Carolina B.), Taylor, A. (Anne), Taylor, J. (Julie), Tell, G.S. (Grethe S.), Tello, T. (Tania), Thankappan, K.R. (K. R.), Thijs, L. (Lutgarde), Thuesen, B.H. (Betina H.), Toft, U. (Ulla), Tolonen, H.K. (Hanna K.), Tolstrup, J.S. (Janne), Topbas, M. (Murat), Topór-Madry, R. (Roman), Tormo, M.J., Tornaritis, M.J. (Michael J.), Torrent, M. (Maties), Torres-Collado, L. (Laura), Traissac, P. (Pierre), Trinh, O.T.H. (Oanh T. H.), Truthmann, J. (Julia), Tsugane, S. (Shoichiro), Tulloch-Reid, M.K. (Marshall K.), Tuomainen, T.-P. (Tomi-Pekka), Tuomilehto, J. (Jaakko), Tybjaerg-Hansen, A. (Anne), Tzourio, C. (Christophe), Ueda, P. (Peter), Ugel, E. (Eunice), Ulmer, H. (Hanno), Unal, B. (Belgin), Uusitalo, H., Valdivia, G. (Gonzalo), Valvi, D. (Damaskini), Dam, R.M. (Rob) van, Schouw, Y.T. (Yvonne) van der, Van Herck, K. (Koen), Van Minh, H. (Hoang), Rossem, L. (Lenie) van, Schoor, N.M. (Natasja) van, Valkengoed, I. (Irene) van, Vanderschueren, D. (Dirk), Vanuzzo, D. (Diego), Varbo, A. (Anette), Varona-Pérez, P. (Patricia), Vasan, S.K. (Senthil K.), Vatten, L. (Lars), Vega, T. (Tomas), Veidebaum, T. (Toomas), Velasquez-Melendez, G. (Gustavo), Venero-Fernández, S.J. (Silvia J.), Veronesi, G. (Giovanni), Verschuren, W.M.M. (W. M. Monique), Victora, C.G. (Cesar G.), Vidiawati, D. (Dhanasari), Viet, L. (Lucie), Villalpando, S. (Salvador), Vioque, J. (Jesus), Virtanen, J.K. (Jyrki K.), Visvikis-Siest, S. (Sophie), Viswanathan, B. (Bharathi), Vlasoff, T. (Tiina), Vollenweider, P. (Peter), Voutilainen, A. (Ari), Wade, A.N. (Alisha N.), Wagner, A. (Aline), Walton, J. (Janette), Bebakar, W.M.W. (Wan Mohamad Wan), Mohamud, W.N.W. (Wan Nazaimoon Wan), Wang, M.-D. (Ming-Dong), Wang, N. (Ningli), Wang, Q. (Qian), Wang, Y.X. (Ya Xing), Wang, Y.-W. (Ying-Wei), Wannamethee, S.G. (Goya), Wedderkopp, N. (Niels), Wei, W. (Wenbin), Whincup, P.H. (Peter), Widhalm, K. (Kurt), Widyahening, I.S. (Indah S.), Wiecek, A. (Andrzej), Wijga, A.H. (Alet), Wilks, R.J. (Rainford J.), Willeit, J. (Johann), Willeit, P. (Peter), Wilsgaard, T. (Tom), Wojtyniak, B. (Bogdan), Wong-McClure, R.A. (Roy A.), Wong, A. (Andrew), Wong, T.Y. (Tien Yin), Woo, J. (Jean), Woodward, M. (Mark), Wu, F.C. (Frederick C.), Wu, S. (Shouling), Xu, H. (Haiquan), Xu, L. (Liang), Yan, W. (Weili), Yang, X. (Xiaoguang), Yasuharu, T. (Tabara), Ye, X. (Xingwang), Yeow, T.P. (Toh Peng), Yiallouros, P.K. (P.), Yoosefi, M. (Moein), Yoshihara, A. (Akihiro), You, S.-L. (San-Lin), Younger-Coleman, N.O. (Novie O.), Yusoff, A.F. (Ahmad Faudzi), Zainuddin, A.A. (Ahmad A.), Zakavi, S.R. (Seyed Rasoul), Zali, M.R. (Mohammad Reza), Zamani, F. (Farhad), Zambon, S. (Sabina), Zampelas, A. (Antonis), Zaw, K.K. (Ko Ko), Zdrojewski, T. (T.), Vrkic, T.Z. (Tajana Zeljkovic), Zhang, Z.-Y. (Zhen-Yu), Zhao, W. (Wenhua), Zhen, S. (Shiqi), Zheng, Y. (Yingfeng), Zholdin, B. (Bekbolat), Zhussupov, B. (Baurzhan), Zoghlami, N. (Nada), Cisneros, J.Z. (Julio Zuñiga), Gregg, E.W. (Edward W.), Ezzati, M. (Majid), Taddei, C. (Cristina), Zhou, B. (Bin), Bixby, H. (Honor), Carrillo-Larco, R.M. (Rodrigo M.), Danaei, G. (Goodarz), Jackson, R.T. (Rod T.), Farzadfar, F. (Farshad), Sophiea, M.K. (Marisa K.), Di Cesare, M. (Mariachiara), Iurilli, M.L.C. (Maria Laura Caminia), Martinez, A.R. (Andrea Rodriguez), Asghari, G. (Golaleh), Dhana, K. (Klodian), Gulayin, P. (Pablo), Kakarmath, S. (Sujay), Santero, M. (Marilina), Voortman, R.G. (Trudy), Riley, L.M. (Leanne M.), Cowan, M.J. (Melanie J.), Savin, S. (Stefan), Bennett, J.E. (James E.), Stevens, G.A. (Gretchen A.), Paciorek, C.J. (Christopher J.), Aekplakorn, W. (Wichai), Cifkova, R. (Renata), Giampaoli, S. (Simona), Kengne, A.P. (Andre Pascal), Khang, Y.-H. (Young-Ho), Kuulasmaa, K. (Kari), Laxmaiah, A. (Avula), Margozzini, P. (Paula), Mathur, P. (Prashant), Nordestgaard, B.G. (Børge), Zhao, D. (Dong), Aadahl, M. (Mette), Abarca-Gómez, L. (Leandra), Rahim, H.A. (Hanan Abdul), Abu-Rmeileh, N.M. (Niveen M.), Acosta-Cazares, B. (Benjamin), Adams, R.J. (Robert J.), Agdeppa, I.A. (Imelda A.), Aghazadeh-Attari, J. (Javad), Aguilar-Salinas, C.A. (Carlos A.), Agyemang, C.O. (Charles), Ahluwalia, T.S. (Tarunveer Singh), Ahmad, N.A. (Noor Ani), Ahmadi, A. (Ali), Ahmadi, N. (Naser), Ahmed, S.H. (Soheir H.), Ahrens, W. (W.), Ajlouni, K. (Kamel), Alarouj, M. (Monira), AlBuhairan, F. (Fadia), AlDhukair, S. (Shahla), Ali, M.M. (Mohamed M.), Alkandari, A. (Abdullah), Alkerwi, A. (Ala’a), Aly, E. (Eman), Amarapurkar, D.N. (Deepak N.), Amouyel, P. (Philippe), Andersen, L.B. (Lars Bo), Anderssen, S.A. (Sigmund A.), Anjana, R.M. (Ranjit Mohan), Ansari-Moghaddam, A. (Alireza), Aounallah-Skhiri, H. (Hajer), Araújo, J. (Joana), Ariansen, I. (Inger), Aris, T. (Tahir), Arku, R.E. (Raphael E.), Arlappa, N. (Nimmathota), Aryal, K.K. (Krishna K.), Aspelund, T. (Thor), Assunção, M.C.F. (Maria Cecília F.), Auvinen, J. (Juha), Avdicová, M. (Mária), Azevedo, A. (Ana), Azizi, J. (Joshan), Azmin, M. (Mehrdad), Balakrishna, N. (Nagalla), Bamoshmoosh, M. (Mohamed), Banach, M. (Maciej), Bandosz, P. (Piotr), Banegas, J.R. (José R.), Barbagallo, C.M. (Carlo M.), Barceló, A. (Alberto), Barkat, A. (Amina), Bata, I. (Iqbal), Batieha, A.M. (Anwar M.), Batyrbek, A. (Assembekov), Baur, L.A. (Louise A.), Beaglehole, R. (Robert), Belavendra, A. (Antonisamy), Ben Romdhane, H. (Habiba), Benet, M. (Mikhail), Benn, M. (Marianne), Berkinbayev, S. (Salim), Bernabe-Ortiz, A. (Antonio), Bernotiene, G. (Gailute), Bettiol, H. (Heloisa), Bhargava, S.K. (Santosh K.), Bi, Y. (Yufang), Bienek, A. (Asako), Bikbov, M. (Mukharram), Bista, B. (Bihungum), Bjerregaard, P. (Peter), Bjertness, E. (Espen), Bjertness, M.B. (Marius B.), Björkelund, C. (Cecilia), Bloch, K.V. (Katia V.), Blokstra, A. (Anneke), Bo, S. (Simona), Boehm, B.O. (Bernhard O.), Boggia, J.G. (Jose G.), Boissonnet, C.P. (Carlos P.), Bonaccio, M. (Marialaura), Bongard, V. (Vanina), Borchini, R. (Rossana), Borghs, H. (Herman), Bovet, P. (Pascal), Brajkovich, I. (Imperia), Breckenkamp, J. (Juergen), Brenner, H. (Hermann), Brewster, L.M. (Lizzy), Bruno, G. (Graziella), Bugge, A. (Anna), Busch, M.A. (Markus A.), de León, A.C. (Antonio Cabrera), Cacciottolo, J. (Joseph), Can, G. (Günay), Cândido, A.P.C. (Ana Paula C.), Capanzana, M.V. (Mario V.), Capuano, E. (Eduardo), Capuano, V. (Vincenzo), Cardoso, V.C. (Viviane C.), Carvalho, J. (Joana), Casanueva, F.F., Censi, L. (Laura), Chadjigeorgiou, C.A. (Charalambos A.), Chamukuttan, S. (Snehalatha), Chaturvedi, N. (Nish), Chen, C.-J. (Chien-Jen), Chen, F. (Fangfang), Chen, S. (Shuohua), Cheng, C.-Y. (Ching-Yu), Cheraghian, B. (Bahman), Chetrit, A. (Angela), Chiou, S.-T. (Shu-Ti), Chirlaque, M.D. (M.), Cho, B. (Belong), Cho, Y. (Yumi), Chudek, J. (Jerzy), Claessens, F. (Frank), Clarke, J. (Janine), Clays, E. (Els), Concin, H. (Hans), Confortin, S.C. (Susana C.), Cooper, C. (Charles), Costanzo, S. (Simona), Cottel, D. (Dominique), Cowell, C. (Chris), Crujeiras, A.B. (Ana B.), Csilla, S. (Semánová), Cui, L. (Liufu), Cureau, F.V. (Felipe V.), D’Arrigo, G. (Graziella), d’Orsi, E. (Eleonora), Dallongeville, J., Damasceno, A. (Albertino), Dankner, R. (Rachel), Dantoft, T.M. (Thomas M.), Dauchet, L. (Luc), Davletov, K. (Kairat), Backer, G. (Guy) de, Bacquer, D. (Dirk) de, de Gaetano, G. (Giovanni), De Henauw, S. (Stefaan), de Oliveira, P.D. (Paula Duarte), De Ridder, D. (David), De Smedt, D. (Delphine), Deepa, M. (Mohan), Deev, A.D. (Alexander D.), Dehghan, A. (Abbas), Delisle, H. (Hélène), Dennison, E.M. (Elaine), Deschamps, V. (Valérie), Dhimal, M. (Meghnath), Di Castelnuovo, A.F. (Augusto F.), Dika, Z. (Zivka), Djalalinia, S. (Shirin), Dobson, A.J. (Annette J.), Donfrancesco, C. (Chiara), Donoso, S.P. (Silvana P.), Döring, A. (Angela), Dorobantu, M. (Maria), Dragano, N. (Nico), Drygas, W. (Wojciech), Du, Y. (Yong), Duante, C.A. (Charmaine A.), Duda, R.B. (Rosemary B.), Dzerve, V. (Vilnis), Dziankowska-Zaborszczyk, E. (Elzbieta), Eddie, R. (Ricky), Eftekhar, E. (Ebrahim), Eggertsen, R. (Robert), Eghtesad, S. (Sareh), Eiben, G. (Gabriele), Ekelund, U. (Ulf), El Ati, J. (Jalila), Eldemire-Shearer, D. (Denise), Eliasen, M. (Marie), Elosua, R. (Roberto), Erasmus, R.T. (Rajiv T.), Erbel, R. (Raimund), Erem, C. (Cihangir), Eriksen, L. (Louise), Hagen, K. (Knut), Escobedo-de la Peña, J. (Jorge), Eslami, S. (Saeid), Esmaeili, A. (Ali), Evans, A. (Alun), Faeh, D. (David), Fall, C.H. (Caroline H.), Faramarzi, E. (Elnaz), Farjam, M. (Mojtaba), Fattahi, M.R. (Mohammad Reza), Felix-Redondo, F.J. (Francisco J.), Ferguson, T.S. (Trevor S.), Fernández-Bergés, D. (Daniel), Ferrante, D. (Daniel), Ferrari, M. (Marika), Ferreccio, C. (Catterina), Ferrieres, J. (Jean), Föger, B. (Bernhard), Foo, L.H. (Leng Huat), Forslund, A.-S. (Ann-Sofie), Forsner, M. (Maria), Fouad, H.M. (Heba M.), Francis, D.K. (Damian K.), do Carmo Franco, M. (Maria), Franco, O.H. (Oscar H.), Frontera, G. (Guillermo), Fujita, Y. (Yuki), Fumihiko, M. (Matsuda), Furusawa, T. (Takuro), Gaciong, Z. (Zbigniew), Galvano, F. (Fabio), Gao, J. (Jingli), Garcia-de-la-Hera, M. (Manoli), Garnett, S.P. (Sarah P.), Gaspoz, J.-M. (Jean-Michel), Gasull, M. (Magda), Gazzinelli, A. (Andrea), Geleijnse, J.M. (Marianne), Ghanbari, A. (Ali), Ghasemi, E. (Erfan), Gheorghe-Fronea, O.-F. (Oana-Florentina), Ghimire, A. (Anup), Gianfagna, F. (Francesco), Gill, T.K. (Tiffany K.), Giovannelli, J. (Jonathan), Gironella, G. (Glen), Giwercman, A. (Aleksander), Goltzman, D. (David), Gonçalves, H. (Helen), Gonzalez-Chica, D.A. (David A.), Gonzalez-Gross, M. (Marcela), González-Rivas, J.P. (Juan P.), González-Villalpando, C. (Clicerio), González-Villalpando, M.E. (María Elena), Gonzalez, A.R. (Angel R.), Gottrand, F., Graff-Iversen, S. (Sidsel), Grafnetter, D. (Dušan), Gregor, R.D. (Ronald D.), Grodzicki, T. (Tomasz), Grøntved, A. (Anders), Grosso, G. (Giuseppe), Gruden, G. (Gabriella), Gu, D. (Dongfeng), Guallar-castillón, P. (Pilar), Guan, O.P. (Ong Peng), Gudmundsson, E.F. (Elias F.), Gudnason, V. (Vilmundur), Guerrero, R. (Ramiro), Guessous, I. (Idris), Gunnlaugsdottir, J. (Johanna), Gupta, R. (Rajeev), Gutierrez, L. (Laura), Gutzwiller, F. (Felix), Ha, S. (Seongjun), Hadaegh, F. (Farzad), Haghshenas, R. (Rosa), Hakimi, H. (Hamid), Hambleton, I.R. (Ian R.), Hamzeh, B. (Behrooz), Hantunen, S. (Sari), Kumar, R.H. (Rachakulla Hari), Hashemi-Shahri, S.M. (Seyed Mohammad), Hata, J. (Jun), Haugsgjerd, T. (Teresa), Hayes, A.J. (Alison J.), He, J. (Jiang), He, Y. (Yong), Hendriks, M.E. (Marleen), Henriques, A. (Ana), Herrala, S. (Sauli), Heshmat, R. (Ramin), Hill, A.G. (Allan G.), Ho, S.Y. (Sai Yin), Ho, S.C. (Suzanne C.), Hobbs, M. (Michael), Hofman, A. (Albert), Homayounfar, R. (Reza), Hopman, W.M. (Wilma M.), Horimoto, A.R.V.R. (Andrea R. V. R.), Hormiga, C.M. (Claudia M.), Horta, B.L. (Bernardo L.), Houti, L. (Leila), Howitt, C. (Christina), Htay, T.T. (Thein Thein), Htet, A.S. (Aung Soe), Htike, M.M.T. (Maung Maung Than), Huerta, J.M. (José María), Huhtaniemi, I.T. (I.), Huisman, M. (Martijn), Hunsberger, M.L. (Monica L.), Husseini, A. (Abdullatif), Huybrechts, I. (Inge), Hwalla, N. (Nahla), Iacoviello, L. (Licia), Iannone, A.G. (Anna G.), Ibrahim, M.M. (Mohsen), Wong, N.I. (Norazizah Ibrahim), Iglesia, I. (Iris), Ikeda, N. (Nayu), Ikram, M.A. (Arfan), Iotova, V. (Violeta), Irazola, V.E. (Vilma E.), Ishida, T. (Takafumi), Islam, M. (Muhammad), al-Safi Ismail, A. (Aziz), Iwasaki, M. (Masanori), Jacobs, J.M. (Jeremy M.), Jaddou, H.Y. (Hashem Y.), Jafar, T.H. (Tazeen), James, K. (Kenneth), Jamrozik, K., Janszky, I. (Imre), Janus, E. (Edward), Jarvelin, M.-R. (Marjo-Riitta), Jasienska, G. (Grazyna), Jelakovic, A. (Ana), Jelakovic, B. (Bojan), Jennings, G. (Garry), Jensen, G.B. (Gorm), Jeong, S.-L. (Seung-lyeal), Jha, A.K. (Anjani Kumar), Jiang, C.Q. (Chao Qiang), Jimenez, R.O. (Ramon O.), JöCkel, K.-H. (Karl-Heinz), Joffres, M. (Michel), Jokelainen, J.J. (Jari J.), Jonas, J.B. (Jost B.), Jorgensen, T. (Torben), Joshi, P. (Pradeep), Joukar, F. (Farahnaz), Józwiak, J. (Jacek), Juolevi, A. (Anne), Kafatos, A. (Anthony), Kajantie, E. (Eero), Kalter-Leibovici, O. (Ofra), Kamaruddin, N.A. (Nor Azmi), Kamstrup, P.R. (Pia R.), Karki, K.B. (Khem B.), Katz, J. (Joanne), Kauhanen, J. (Jussi), Kaur, P. (Prabhdeep), Kavousi, M. (Maryam), Kazakbaeva, G. (Gyulli), Keil, M. (Mark), Keinanen-Kiukaanniemi, S. (Sirkka), Kelishadi, R. (Roya), Keramati, M. (Maryam), Kerimkulova, A. (Alina), Kersting, M. (Mathilde), Khader, Y.S. (Yousef Saleh), Khalili, D. (Davood), Khateeb, M. (Mohammad), Kheradmand, M. (Motahareh), Khosravi, A. (Alireza), Kiechl-Kohlendorfer, U. (Ursula), Kiechl, S. (Stefan), Killewo, J. (Japhet), Kim, H.C. (Hyeon Chang), Kim, J. (Jeongseon), Kim, Y.-Y. (Yeon-Yong), Klumbiene, J. (Jurate), Knoflach, M. (Michael), Ko, S. (Stephanie), Kohler, H.-P. (Hans-Peter), Kohler, I.V. (Iliana V.), Kolle, E. (Elin), Kolsteren, P. (Patrick), König, J. (Jürgen), Korpelainen, R. (Raija), Korrovits, P. (Paul), Kos, J. (Jelena), Koskinen, S. (Seppo), Kouda, K. (Katsuyasu), Kowlessur, S. (Sudhir), Kratzer, W. (Wolfgang), Kriemler, S. (Susi), Kristensen, P.L. (Peter Lund), Krokstad, S. (Steiner), Kromhout, D. (Daan), Kujala, U.M. (Urho), Kurjata, P. (Pawel), Kyobutungi, C. (Catherine), Laamiri, F.Z. (Fatima Zahra), Laatikainen, T. (Tiina), Lachat, C. (Carl), Laid, Y. (Youcef), Lam, T.H. (Tai Hing), Lambrinou, C.-P. (Christina-Paulina), Lanska, V. (Vera), Lappas, G. (Georg), Larijani, B. (Bagher), Latt, T.S. (Tint Swe), Laugsand, L.E. (Lars E.), Lazo-Porras, M. (Maria), Lee, J. (Jeannette), Lee, J. (Jeonghee), Lehmann, N. (Nils), Lehtimäki, T. (Terho), Levitt, N.S. (Naomi S.), Li, Y. (Yanping), Lilly, C.L. (Christa L.), Lim, W.-Y. (Wei-Yen), Lima-Costa, M.F. (Maria Fernanda), Lin, H.-H. (Hsien-Ho), Lin, X. (Xu), Lin, Y.-T. (Yi-Ting), Kao, W.H.L. (Wen), Linneberg, A. (Allan), Lissner, L. (Lauren), Liu, J. (Jing), Loit, H.-M. (Helle-Mai), Lopez-Garcia, E. (Esther), Lopez, T. (Tania), Lotufo, P.A. (Paulo A), Lozano, J.E. (José Eugenio), Luksiene, D. (Dalia), Lundqvist, A. (Annamari), Lundqvist, R. (Robert), Lunet, N. (Nuno), Ma, G. (Guansheng), Machado-Coelho, G.L.L. (George L. L.), Machado-Rodrigues, A.M. (Aristides M.), Machi, S. (Suka), Madar, A.A. (Ahmed A.), Maggi, S. (Stefania), Magliano, D.J., Magriplis, E. (Emmanuella), Mahasampath, G. (Gowri), Maire, B. (Bernard), Makdisse, M. (Marcia), Malekzadeh, F. (Fatemeh), Malekzadeh, R. (Reza), Rao, K.M. (Kodavanti Mallikharjuna), Manios, Y., Mann, J.I. (Jim I.), Mansour-Ghanaei, F. (Fariborz), Manzato, E. (Enzo), Marques-Vidal, P. (Pedro), Martorell, R. (Reynaldo), Mascarenhas, L.P. (Luis P.), Mathiesen, E.B. (Ellisiv), Matsha, T.E. (Tandi E.), Mavrogianni, C. (Christina), McFarlane, S.R. (Shelly R.), McGarvey, S.T. (Stephen T.), McLachlan, S. (Stela), McLean, R.M. (Rachael M.), McLean, S.B. (Scott B.), McNulty, B.A. (Breige A.), Mediene-Benchekor, S. (Sounnia), Mehdipour, P. (Parinaz), Mehlig, K. (Kirsten), Mehrparvar, A.H. (Amir Houshang), Meirhaeghe, A. (Aline), Meisinger, C. (Christa), Menezes, A.M.B. (Ana M.B.), Menon, G.R. (Geetha R.), Merat, S. (Shahin), Mereke, A. (Alibek), Meshram, I.I. (Indrapal I.), Metcalf, P. (Patricia), Meyer, H.E. (Haakon E.), Mi, J. (Jie), Michels, N. (Nathalie), Miller, J.C. (Jody C.), Minderico, C.S. (Cláudia S.), Mini, G.K. (G. K.), Miquel, J.F. (Juan Francisco), Miranda, J.J. (J. Jaime), Mirjalili, M.R. (Mohammad Reza), Mirrakhimov, E. (Erkin), Modesti, P.A. (Pietro A.), Moghaddam, S.S. (Sahar Saeedi), Mohajer, B. (Bahram), Mohamed, M.K. (Mostafa K.), Mohammad, K. (Kazem), Mohammadi, Z. (Zahra), Mohammadifard, N. (Noushin), Mohammadpourhodki, R. (Reza), Mohan, V. (Viswanathan), Mohanna, S. (Salim), Yusoff, M.F.M. (Muhammad Fadhli Mohd), Mohebbi, I. (Iraj), Mohebi, F. (Farnam), Moitry, M. (Marie), Møllehave, L.T. (Line T.), Møller, N.C. (Niels C.), Molnár, D. (Dénes), Momenan, A. (Amirabbas), Mondo, C.K. (Charles K.), Monterrubio-Flores, E. (Eric), Moosazadeh, M. (Mahmood), Morejon, A. (Alain), Moreno, L. (Luis), Morgan, K. (Karen), Morin, S.N. (Suzanne N.), Moschonis, G. (George), Mossakowska, M. (Malgorzata), Mostafa, A. (Aya), Mota, J. (Jorge), Motlagh, M.E. (Mohammad Esmaeel), Motta, J. (Jorge), Msyamboza, K.P. (Kelias P.), Muiesan, M.L. (Maria Lorenza), Müller-Nurasyid, M. (Martina), Mursu, J. (Jaakko), Mustafa, N. (Norlaila), Nabipour, I. (Iraj), Naderimagham, S. (Shohreh), Nagel, G. (Gabriele), Naidu, B.M. (Balkish M.), Najafi, F. (Farid), Nakamura, H. (Harunobu), Námešná, J. (Jana), Nang, E.E.K. (Ei Ei K.), Nangia, V.B. (Vinay B.), Nauck, M. (Matthias), Neal, W.A. (William A.), Nejatizadeh, A. (Azim), Nenko, I. (Ilona), Nervi, F. (Flavio), Nguyen, N.D. (Nguyen D.), Nguyen, Q.N. (Quang Ngoc), Nieto-Martínez, R.E. (Ramfis E.), Nihal, T. (Thomas), Niiranen, T.J. (Teemu J.), Ning, G. (Guang), Ninomiya, T. (Toshiharu), Noale, M. (Marianna), Noboa, O.A. (Oscar A.), Noto, D. (Davide), Nsour, M.A. (Mohannad Al), Nuhoğlu, I. (Irfan), O’Neill, T.W. (Terence W.), O’Reilly, D. (Dermot), Ochoa-Avilés, A.M. (Angélica M.), Oh, K. (Kyungwon), Ohtsuka, R. (Ryutaro), Olafsson, Ö. (Örn), Olié, V. (Valérie), Oliveira, I.O. (Isabel O.), Omar, M.A. (Mohd Azahadi), Onat, A. (Altan), Ong, S.K. (Sok King), Ordunez, P. (Pedro), Ornelas, R. (Rui), Ortiz, P.J. (Pedro J.), Osmond, C. (Clive), Ostojic, S.M. (Sergej M.), Ostovar, A. (Afshin), Otero, J.A. (Johanna A.), Owusu-Dabo, E. (Ellis), Paccaud, F.M. (Fred Michel), Pahomova, E. (Elena), Pajak, A. (Andrzej), Palmieri, L. (Luigi), Pan, W.-H. (Wen-Harn), Panda-Jonas, S. (Songhomitra), Panza, F. (Francesco), Parnell, W.R. (Winsome R.), Patel, N.D. (Nikhil D.), Peer, N. (Nasheeta), Peixoto, S.V. (Sergio Viana), Peltonen, M. (Markku), Pereira, A. (A.), Peters, A. (Annette), Petersmann, A. (Astrid), Petkeviciene, J. (Janina), Peykari, N. (Niloofar), Pham, S.T. (Son Thai), Pichardo, R.N. (Rafael N.), Pigeot, I. (Iris), Pilav, A. (Aida), Pilotto, A. (Alberto), Piwonska, A. (Aleksandra), Pizarro, A.N. (Andreia N.), Plans-Rubió, P. (Pedro), Plata, S. (Silvia), Pohlabeln, H. (Hermann), Porta, M. (Miquel), Portegies, M.L.P. (Marileen), Poudyal, A. (Anil), Pourfarzi, F. (Farhad), Poustchi, H. (Hossein), Pradeepa, R. (Rajendra), Price, J.F. (Jacqueline F.), Providencia, R. (Rui), Puder, J.J. (Jardena J.), Puhakka, S.E. (Soile E.), Punab, M. (Margus), Qorbani, M. (Mostafa), Bao, T.Q. (Tran Quoc), Radisauskas, R. (Ricardas), Rahimikazerooni, S. (Salar), Raitakari, O. (Olli), Rao, S.R. (Sudha Ramachandra), Ramachandran, A. (Ambady), Ramos, E. (Elisabete), Ramos, R. (Rafel), Rampal, L. (Lekhraj), Rampal, S. (Sanjay), Redón, J. (Josep), Reganit, P.F.M. (Paul Ferdinand M.), Revilla, L. (Luis), Rezaianzadeh, A. (Abbas), Ribeiro, R. (Robespierre), Richter, A. (Adrian), Rigo, F. (Fernando), Rinke de Wit, T.F. (Tobias), Rodríguez Artalejo, F. (Fernando), del Cristo Rodriguez-Perez, M. (María), Rodríguez-Villamizar, L.A. (Laura A.), Roggenbuck, U. (Ulla), Rojas-Martinez, R. (Rosalba), Romaguera, D. (Dora), Romeo, E.L. (Elisabetta L.), Rosengren, A. (Annika), Roy, J.G.R. (Joel G. R.), Rubinstein, A. (Adolfo), Ruidavets, J.-B. (Jean-Bernard), Ruiz-Betancourt, B.S. (Blanca Sandra), Russo, P. (Paola), Rust, P. (Petra), Rutkowski, M. (Marcin), Sabanayagam, C. (Charumathi), Sachdev, H.S. (Harshpal S.), Sadjadi, A. (Alireza), Safarpour, A.R. (Ali Reza), Safiri, S. (Saeid), Saidi, O. (Olfa), Saki, N. (Nader), Salanave, B. (Benoit), Salmerón, D. (Diego), Salomaa, V. (Veikko), Salonen, J.T. (Jukka T.), Salvetti, M. (Massimo), Sánchez-Abanto, J. (Jose), Sans, S. (Susana), Santaliestra-Pasías, A.M. (Alba M.), Santos, D.A. (Diana A.), Santos, M.P. (Maria Paula), Santos, R. (Rute), Saramies, J.L. (Jouko L.), Sardinha, L.B. (Luis B.), Sarrafzadegan, N. (Nizal), Saum, K.-U. (Kai-Uwe), Savva, S., Sawada, N. (Norie), Sbaraini, M. (Mariana), Scazufca, M. (Marcia), Schaan, B.D. (Beatriz D.), Schargrodsky, H. (Herman), Scheidt-Nave, C. (C.), Schienkiewitz, A. (Anja), Schipf, S. (Sabine), Schmidt, C.O. (Carsten O.), Schöttker, B. (Ben), Schramm, S. (Sara), Sebert, S. (Sylvain), Sein, A.A. (Aye Aye), Sen, A. (Abhijit), Sepanlou, S.G. (Sadaf G), Servais, J. (Jennifer), Shakeri, R. (Ramin), Shalnova, S.A. (Svetlana A.), Shamah-Levy, T. (Teresa), Sharafkhah, M. (Maryam), Sharma, S.K. (Sanjib K.), Shaw, J.E., Shayanrad, A. (Amaneh), Shi, Z. (Zumin), Shibuya, K. (Kenji), Shimizu-Furusawa, H. (Hana), Shin, D.W. (Dong Wook), Shin, Y. (Youchan), Shirani, M. (Majid), Shiri, R. (Rahman), Shrestha, N. (Namuna), Si-Ramlee, K. (Khairil), Siani, A. (Alfonso), Siantar, R. (Rosalynn), Sibai, A.M. (Abla M.), Silva, D.A.S. (Diego Augusto Santos), Simon, M. (Mary), Simons, J. (Judith), Simons, L.A. (Leon A.), Sjöström, M. (Michael), Skaaby, T. (Tea), Slowikowska-Hilczer, J. (Jolanta), Slusarczyk, P. (Przemyslaw), Smeeth, L. (Liam), Snijder, M.B. (Marieke), Söderberg, S. (Stefan), Soemantri, A. (Augustinus), Sofat, R. (Reecha), Solfrizzi, V. (Vincenzo), Somi, M.H. (Mohammad Hossein), Sonestedt, E. (Emily), Sørensen, T.I.A. (Thorkild), Jérome, C.S. (Charles Sossa), Soumaré, A. (Aicha), Sozmen, K. (Kaan), Sparrenberger, K. (Karen), Staessen, J.A. (Jan), Stathopoulou, M.G. (Maria G), Stavreski, B. (Bill), Steene-Johannessen, J. (Jostein), Stehle, P. (Peter), Stein, A.D. (Aryeh D.), Stessman, J. (Jochanan), Stevanović, R. (Ranko), Stieber, J. (Jutta), Stöckl, D. (Doris), Stokwiszewski, J. (Jakub), Stronks, K. (Karien), Strufaldi, M.W. (Maria Wany), Suárez-Medina, R. (Ramón), Sun, C.-A. (Chien-An), Sundström, J. (Johan), Suriyawongpaisal, P. (Paibul), Sy, R.G. (Rody G.), Sylva, R.C. (René Charles), Szklo, M. (Moyses), Tai, E.S. (Shyong), Tamosiunas, A. (Abdonas), Tan, E.J. (Eng Joo), Tarawneh, M.R. (Mohammed Rasoul), Tarqui-Mamani, C.B. (Carolina B.), Taylor, A. (Anne), Taylor, J. (Julie), Tell, G.S. (Grethe S.), Tello, T. (Tania), Thankappan, K.R. (K. R.), Thijs, L. (Lutgarde), Thuesen, B.H. (Betina H.), Toft, U. (Ulla), Tolonen, H.K. (Hanna K.), Tolstrup, J.S. (Janne), Topbas, M. (Murat), Topór-Madry, R. (Roman), Tormo, M.J., Tornaritis, M.J. (Michael J.), Torrent, M. (Maties), Torres-Collado, L. (Laura), Traissac, P. (Pierre), Trinh, O.T.H. (Oanh T. H.), Truthmann, J. 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(San-Lin), Younger-Coleman, N.O. (Novie O.), Yusoff, A.F. (Ahmad Faudzi), Zainuddin, A.A. (Ahmad A.), Zakavi, S.R. (Seyed Rasoul), Zali, M.R. (Mohammad Reza), Zamani, F. (Farhad), Zambon, S. (Sabina), Zampelas, A. (Antonis), Zaw, K.K. (Ko Ko), Zdrojewski, T. (T.), Vrkic, T.Z. (Tajana Zeljkovic), Zhang, Z.-Y. (Zhen-Yu), Zhao, W. (Wenhua), Zhen, S. (Shiqi), Zheng, Y. (Yingfeng), Zholdin, B. (Bekbolat), Zhussupov, B. (Baurzhan), Zoghlami, N. (Nada), Cisneros, J.Z. (Julio Zuñiga), Gregg, E.W. (Edward W.), and Ezzati, M. (Majid)
- Abstract
High blood cholesterol is typically considered a feature of wealthy western countries1,2. However, dietary and behavioural determinants of blood cholesterol are changing rapidly throughout the world3 and countries are using lipid-lowering medications at varying rates. These changes can have distinct effects on the levels of high-density lipoprotein (HDL) cholesterol and non-HDL cholesterol, which have different effects on human health4,5. However, the trends of HDL and non-HDL cholesterol levels over time have not been previously reported in a global analysis. Here we pooled 1,127 population-based studies that measured blood lipids in 102.6 million individuals aged 18 years and older to estimate trends from 1980 to 2018 in mean total, non-HDL and HDL cholesterol levels for 200 countries. Globally, there was little change in total or non-HDL cholesterol from 1980 to 2018. This was a net effect of increases in low- and middle-income countries, especially in east and southeast Asia, and decreases in high-income western countries, especially those in northwestern Europe, and in central and eastern Europe. As a result, countries with the highest level of non-HDL cholesterol—which is a marker of cardiov
- Published
- 2020
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39. National trends in total cholesterol obscure heterogeneous changes in HDL and non-HDL cholesterol and total-to-HDL cholesterol ratio: a pooled analysis of 458 population-based studies in Asian and Western countries
- Author
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Zdrojewski, T, Zhao, D, Stevens, GA, Savin, S, Cowan, MJ, Riley, LM, Ezzati, M, Adams, RJ, Ahrens, W, Amouyel, P, Amuzu, A, Anderssen, SA, Ariansen, I, Arveiler, D, Aspelund, T, Auvinen, J, Avdicova, M, Banach, M, Bandosz, P, Banegas, JR, Barbagallo, CM, Bata, I, Baur, LA, Beaglehole, R, Bernotiene, G, Bi, Y, Bienek, A, Bjorkelund, C, Bo, S, Boehm, BO, Bonaccio, M, Bongard, V, Borchini, R, Borghs, H, Breckenkamp, J, Brenner, H, Bruno, G, Busch, MA, Cabrera de Leon, A, Capuano, V, Casanueva, FF, Casas, J-P, Caserta, CA, Censi, L, Chen, F, Chen, S, Chirlaque, M-D, Cho, B, Cho, Y, Chudek, J, Claessens, F, Clarke, J, Clays, E, Cooper, C, Costanzo, S, Cottel, D, Cowell, C, Crujeiras, AB, Cui, L, D'Arrigo, G, Dauchet, L, De Backer, G, De Bacquer, D, de Gaetano, G, De Henauw, S, De Smedt, D, Dennison, E, Deschamps, V, Di Castelnuovo, A, Dobson, AJ, Donfrancesco, C, Doering, A, Drygas, W, Du, Y, Dziankowska-Zaborszczyk, E, Eggertsen, R, Ekelund, U, Elosua, R, Eriksson, JG, Evans, A, Faeh, D, Felix-Redondo, FJ, Fernandez-Berges, D, Ferrari, M, Ferrieres, J, Finn, JD, Forslund, A-S, Forsner, M, Frontera, G, Fujita, Y, Gaciong, Z, Galvano, F, Gao, J, Garcia-de-la-Hera, M, Garnett, SP, Gaspoz, J-M, Gasull, M, Gates, L, Gianfagna, F, Gill, TK, Giovannelli, J, Giwercman, A, Goltzman, D, Gonzalez Gross, M, Gottrand, F, Graff-Iversen, S, Grafnetter, D, Gregor, RD, Grodzicki, T, Grosso, G, Gruden, G, Gu, D, Guallar-Castillon, P, Gudmundsson, EF, Guessous, I, Gunnlaugsdottir, J, Gutzwiller, F, Hardy, R, Hata, J, Haugsgjerd, T, Hayes, AJ, He, J, He, Y, Herrala, S, Hihtaniemi, IT, Hobbs, M, Hopman, WM, Maria Huerta, J, Huybrechts, I, Iacoviello, L, Iannone, AG, Ikeda, N, Iwasaki, M, Jamrozik, K, Janszky, I, Jarvelin, M-R, Jasienska, G, Jennings, G, Jeong, S-L, Jiang, CQ, Joffres, M, Jokelainen, JJ, Jonas, JB, Jozwiak, J, Kajantie, EO, Kauhanen, J, Keil, U, Keinanen-Kiukaanniemi, S, Kersting, M, Kiechl-Kohlendorfer, U, Kiechl, S, Kim, J, Kim, Y-Y, Klumbiene, J, Knoflach, M, Ko, S, Kolle, E, Korpelainen, R, Koskinen, S, Kouda, K, Kratzer, W, Kriemler, S, Krokstad, S, Kujala, UM, Kurjata, P, Lam, TH, Lanska, V, Lappas, G, Laugsand, LE, Lee, J, Lehtimaki, T, Li, Y, Lilly, CL, Lin, X, Lind, L, Lissner, L, Liu, J, Lopez-Garcia, E, Lorbeer, R, Eugenio Lozano, J, Luksiene, D, Lundqvist, A, Lundqvist, R, Lytsy, P, Ma, G, Machi, S, Maggi, S, Magliano, DJ, Manzato, E, Mathiesen, EB, McLachlan, S, McLean, RM, McLean, SB, Meirhaeghe, A, Meisinger, C, Metcalf, P, Mi, J, Miller, JC, Moreno, LA, Morin, SN, Mossakowska, M, Muiesan, ML, Mursu, J, Nakamura, H, Namesna, J, Nauck, M, Maria Navarrete-Munoz, E, Neal, WA, Nenko, I, Niiranen, TJ, Ning, G, Noale, M, Norie, S, Noto, D, O'Neill, T, O'Reilly, D, Oh, K, Olafsson, O, Paccaud, FM, Pajak, A, Palmieri, L, Panza, F, Parnell, WR, Peltonen, M, Peters, A, Petersmann, A, Pigeot, I, Pilotto, L, Piwonska, A, Plans-Rubio, P, Porta, M, Price, JF, Puder, JJ, Puhakka, SE, Radisauskas, R, Raitakari, O, Ramos, R, Redon, J, Rigo, F, del Cristo Rodriguez-Perez, M, Romaguera, D, Ronkainen, K, Rosengren, A, Roy, JGR, Ruidavets, J-B, Rutkowski, M, Salanave, B, Salmeron, D, Salomaa, V, Salonen, JT, Salvetti, M, Sans, S, Saramies, JL, Saum, K-U, Scheidt-Nave, C, Schienkiewitz, A, Schipf, S, Schmidt, CO, Schoettker, B, Sebert, S, Sen, A, Shaw, JE, Shibuya, K, Shin, DW, Shiri, R, Simons, J, Simons, LA, Sjostrom, M, Slowikowska-Hilczer, J, Slusarczyk, P, Solfrizzi, V, Sonestedt, E, Soumare, A, Staessen, JA, Stathopoulou, MG, Steene-Johannessen, J, Stehle, P, Stieber, J, Stoeckl, D, Stokwiszewski, J, Sundstrom, J, Suriyawongpaisal, P, Tamosiunas, A, Tan, EJ, Taylor, A, Tell, G, Thijs, L, Tolonen, HK, Topor-Madry, R, Jose Tormo, M, Torrent, M, Tsugane, S, Tuomainen, T-P, Tuomilehto, J, Tzourio, C, Uusitalo, HMT, Van Herck, K, Vanderschueren, D, Vanuzzo, D, Vatten, L, Vega, T, Veronesi, G, Vioque, J, Virtanen, JK, Visvikis-Siest, S, Vollenweider, P, Voutilainen, S, Vrijheid, M, Wagner, A, Wang, M-D, Wang, Q, Wang, YX, Wannamethee, SG, Wei, W, Whincup, PH, Wiecek, A, Willeit, J, Willeit, P, Wojtyniak, B, Wong, A, Woodward, M, Wu, FC, Wu, S, Xu, H, Xu, L, Yan, W, Yang, X, Ye, X, Yoshihara, A, Zambon, S, and Zhao, W
- Abstract
BACKGROUND: Although high-density lipoprotein (HDL) and non-HDL cholesterol have opposite associations with coronary heart disease, multi-country reports of lipid trends only use total cholesterol (TC). Our aim was to compare trends in total, HDL and non-HDL cholesterol and the total-to-HDL cholesterol ratio in Asian and Western countries. METHODS: We pooled 458 population-based studies with 82.1 million participants in 23 Asian and Western countries. We estimated changes in mean total, HDL and non-HDL cholesterol and mean total-to-HDL cholesterol ratio by country, sex and age group. RESULTS: Since ∼1980, mean TC increased in Asian countries. In Japan and South Korea, the TC rise was due to rising HDL cholesterol, which increased by up to 0.17 mmol/L per decade in Japanese women; in China, it was due to rising non-HDL cholesterol. TC declined in Western countries, except in Polish men. The decline was largest in Finland and Norway, at ∼0.4 mmol/L per decade. The decline in TC in most Western countries was the net effect of an increase in HDL cholesterol and a decline in non-HDL cholesterol, with the HDL cholesterol increase largest in New Zealand and Switzerland. Mean total-to-HDL cholesterol ratio declined in Japan, South Korea and most Western countries, by as much as ∼0.7 per decade in Swiss men (equivalent to ∼26% decline in coronary heart disease risk per decade). The ratio increased in China. CONCLUSIONS: HDL cholesterol has risen and the total-to-HDL cholesterol ratio has declined in many Western countries, Japan and South Korea, with only a weak correlation with changes in TC or non-HDL cholesterol.
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- 2020
40. Long COVID neuropsychological deficits after severe, moderate or mild infection
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Voruz, P., primary, Allali, G., additional, Benzakour, L., additional, Nuber-Champier, A., additional, Thomasson, M., additional, Jacot, I., additional, Pierce, J., additional, Lalive, P., additional, Lövblad, K-O., additional, Braillard, O., additional, Coen, M., additional, Serratrice, J., additional, Pugin, J., additional, Ptak, R., additional, Guessous, I., additional, Landis, B.N., additional, Assal, F., additional, and Péron, J.A., additional
- Published
- 2021
- Full Text
- View/download PDF
41. The determinants and consequences of forgoing healthcare
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Petrovic, D, primary, Sandoval, J L, additional, Guessous, I, additional, and Stringhini, S, additional
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- 2020
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42. Association between legal status regularization and self-rated health among undocumented migrants
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Fakhoury, J, primary, Duvoisin, A, additional, Jackson, Y L, additional, Burton-Jeangros, C, additional, Consoli, L, additional, and Guessous, I, additional
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- 2020
- Full Text
- View/download PDF
43. Development of a web-platform for dynamic monitoring of population health in Geneva: Specchio project
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Baysson, H, primary, Joost, S, additional, Attar Cohen, H, additional, Guessous, I, additional, and Stringhini, S, additional
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- 2020
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44. Exploring the relation between methylxanthines and plasma lipids in two population-based studies
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Petrovic, D, primary, Pruijm, M, additional, Ponte, B, additional, Ackermann, D, additional, Ehret, G, additional, Zhang, Z, additional, Thijs, L, additional, Staessen, J, additional, Bochud, M, additional, and Guessous, I, additional
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- 2020
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45. Forgoing health care is associated with insurance deductibles in a consumer-driven health care system
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Sandoval, J L, primary, Petrovic, D, additional, Guessous, I, additional, and Stringhini, S, additional
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- 2020
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46. Thirteen‐year trends in the prevalence of diabetes in an urban region of Switzerland: a population‐based study
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Mestral, C., primary, Stringhini, S., additional, Guessous, I., additional, and Jornayvaz, F. R., additional
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- 2019
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- View/download PDF
47. Socioeconomic position, lifestyle habits and biomarkers of epigenetic aging: a multi-cohort analysis
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Fiorito, G., Mccrory, C., Robinson, O., Carmeli, C., Rosales, C. O., Zhang, Y., Colicino, E., Dugue, P. -A., Artaud, F., Mckay, G. J., Jeong, A., Mishra, P. P., Nost, T. H., Krogh, V., Panico, S., Sacerdote, C., Tumino, R., Palli, D., Matullo, G., Guarrera, S., Gandini, M., Bochud, M., Dermitzakis, E., Muka, T., Schwartz, J., Vokonas, P. S., Just, A., Hodge, A. M., Giles, G. G., Southey, M. C., Hurme, M. A., Young, I., Mcknight, A. J., Kunze, S., Waldenberger, M., Peters, A., Schwettmann, L., Lund, E., Baccarelli, A., Milne, R. L., Kenny, R. A., Elbaz, A., Brenner, H., Kee, F., Voortman, T., Probst-Hensch, N., Lehtimaki, T., Elliot, P., Stringhini, S., Vineis, P., Polidoro, S., Alberts, J., Alenius, H., Avendano, M., Baltar, V., Bartley, M., Barros, H., Bellone, M., Berger, E., Blane, D., Candiani, G., Carra, L., Castagne, R., Chadeau-Hyam, M., Cima, S., Clavel-Chapelon, F., Costa, G., Courtin, E., Delpierre, C., D'Errico, A., Dermitzakis, M., Elovainio, M., Elliott, P., Fagherazzi, G., Fraga, S., Gares, V., Gerbouin-Rerolle, P., Giles, G., Goldberg, M., Greco, D., Guessous, I., Haba-Rubio, J., Heinzer, R., Hodge, A., Joost, S., Karimi, M., Kelly-Irving, M., Kahonen, M., Karisola, P., Khenissi, L., Kivimaki, M., Laine, J., Lang, T., Laurent, A., Layte, R., Lepage, B., Lorsch, D., Macguire, F., Machell, G., Mackenbach, J., Marmot, M., de Mestral, C., Miller, C., Milne, R., Muennig, P., Nusselder, W., Petrovic, D., Pilapil, L., Preisig, M., Pulkki-Raback, L., Raitakari, O., Ribeiro, A. I., Ricceri, F., Recalcati, P., Reinhard, E., Valverde, J. R., Saba, S., Santegoets, F., Satolli, R., Simmons, T., Severi, G., Shipley, M. J., Tabak, A., Terhi, V., Tieulent, J., Vaccarella, S., Vigna-Taglianti, F., Vollenweider, P., Vuilleumier, N., Zins, M., Medical Research Council (MRC), Commission of the European Communities, BIOS Consortium, Lifepath consortium, Epidemiology, Dermitzakis, Emmanouil, and Stringhini, Silvia
- Subjects
Male ,Aging ,Geriatrics & Gerontology ,Disease ,epigenetic clocks ,Bioinformatics ,0601 Biochemistry and Cell Biology ,DISEASE ,Epigenesis, Genetic ,Cohort Studies ,0302 clinical medicine ,Risk Factors ,DNA METHYLATION ,media_common ,0303 health sciences ,education ,Lifepath consortium ,VDP::Medisinske Fag: 700::Helsefag: 800::Samfunnsmedisin, sosialmedisin: 801 ,CARDIOVASCULAR RISK ,Aged ,Aging/genetics ,Aging/psychology ,DNA Methylation ,Educational Status ,Female ,Humans ,Life Style ,Mutation ,Social Class ,biological aging ,socioeconomic position ,Longevity ,ASSOCIATION ,Biological aging ,Education ,Epigenetic clocks ,Socioeconomic position ,3. Good health ,WIDE METHYLATION ,Aging/genetics/psychology ,DNA methylation ,Biomarker (medicine) ,HEALTH ,BIOS Consortium ,Life Sciences & Biomedicine ,Research Paper ,Cohort study ,VDP::Medisinske Fag: 700::Basale medisinske, odontologiske og veterinærmedisinske fag: 710::Medisinsk genetikk: 714 ,media_common.quotation_subject ,CANCER-RISK ,610 Medicine & health ,VDP::Medical disciplines: 700::Basic medical, dental and veterinary science disciplines: 710::Medical genetics: 714 ,Biology ,PERIPHERAL-BLOOD ,03 medical and health sciences ,SDG 3 - Good Health and Well-being ,Genetic ,360 Social problems & social services ,1112 Oncology and Carcinogenesis ,Epigenetics ,ddc:613 ,030304 developmental biology ,Science & Technology ,Mechanism (biology) ,MUTATIONS ,dNaM ,Socioeconomic Position ,Biological Aging ,Epigenetic Clocks ,Cell Biology ,0606 Physiology ,DRIFT ,VDP::Medical disciplines: 700::Health sciences: 800::Community medicine, Social medicine: 801 ,030217 neurology & neurosurgery ,Epigenesis - Abstract
Source at https://doi.org/10.18632/aging.101900. Differences in health status by socioeconomic position (SEP) tend to be more evident at older ages, suggesting the involvement of a biological mechanism responsive to the accumulation of deleterious exposures across the lifespan. DNA methylation (DNAm) has been proposed as a biomarker of biological aging that conserves memory of endogenous and exogenous stress during life. We examined the association of education level, as an indicator of SEP, and lifestyle-related variables with four biomarkers of age-dependent DNAm dysregulation: the total number of stochastic epigenetic mutations (SEMs) and three epigenetic clocks (Horvath, Hannum and Levine), in 18 cohorts spanning 12 countries. The four biological aging biomarkers were associated with education and different sets of risk factors independently, and the magnitude of the effects differed depending on the biomarker and the predictor. On average, the effect of low education on epigenetic aging was comparable with those of other lifestyle-related risk factors (obesity, alcohol intake), with the exception of smoking, which had a significantly stronger effect. Our study shows that low education is an independent predictor of accelerated biological (epigenetic) aging and that epigenetic clocks appear to be good candidates for disentangling the biological pathways underlying social inequalities in healthy aging and longevity.
- Published
- 2019
- Full Text
- View/download PDF
48. Association between colorectal cancer testing and insurance type: Evidence from the Swiss Health Interview Survey 2012
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Braun, A.L., Kässner, A., Syrogiannouli, L., Selby, K., Bulliard, J.L., Martin, Y., Guessous, I., Tal, K., Del Giovane, C., Zwahlen, M., and Auer, R.
- Subjects
Health insurance ,Screening rates ,health care facilities, manpower, and services ,education ,FOBT ,Regular Article ,Colonoscopy ,Colorectal cancer screening ,Switzerland ,digestive system diseases ,health care economics and organizations - Abstract
Highlights • Colonoscopy and FOBT are both recommended for colorectal cancer screening. • Colonoscopy costs much more, so test choice might be linked to insurance type. • Private insurance and low deductibles were associated with more colonoscopies. • FOBT, which is cheap, was not associated with private insurance., Both colonoscopy and fecal occult blood test (FOBT) are commonly used for colorectal cancer (CRC) screening, but colonoscopy costs much more than FOBT. Swiss insurance offers high or low deductibles and choice of basic or private insurance. We hypothesized that high deductibles and basic insurance discourage colonoscopy, but do not change FOBT rates. We determined the proportion of patients tested for CRC in Switzerland (colonoscopy within 10 years, FOBT within 2 years), and determined associations with health insurance type. We extracted data on 50–75-year-olds from the Swiss Health Interview Surveys of 2012 to determine colonoscopy and FOBT testing rates (n = 7335). Multivariate logistic regression models estimated prevalence ratios (PRs) of CRC testing associated with health insurance type (deductible and private insurance), adjusted for socio-demographic factors (age, gender, education, income) and self-rated health. The weighted proportion of individuals tested for CRC within recommended intervals was 39.5%. Testing with colonoscopy was significantly associated with private insurance (PR 1.85, 95% CI: 1.46–2.35) and low deductible (PR 2.00, 95% CI: 1.56–2.57). Testing with FOBT was significantly associated with deductible (PR 1.71, 95%CI:1.09–2.68) but not with private insurance. About 60% of the Swiss population was not current with CRC testing. After adjusting for covariates, private insurance and low deductible was significantly associated with higher prevalence of CRC testing, indicating that waiving the deductible could increase CRC screening uptake and reduce health inequality.
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- 2019
49. Health effects of dietary risks in 195 countries, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017
- Author
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Afshin, A, Sur, PJ, Fay, KA, Cornaby, L, Ferrara, G, Salama, JS, Mullany, EC, Abate, KH, Abbafati, C, Abebe, Z, Afarideh, M, Aggarwal, A, Agrawal, S, Akinyemiju, T, Alahdab, F, Bacha, U, Bachman, VF, Badali, H, Badawi, A, Bensenor, IM, Bernabe, E, Biadgilign, SKK, Biryukov, SH, Cahill, LE, Carrero, JJ, Cercy, KM, Dandona, L, Dandona, R, Dang, AK, Degefa, MG, El Sayed Zaki, M, Esteghamati, A, Esteghamati, S, Fanzo, J, Farinha, CSES, Farvid, MS, Farzadfar, F, Feigin, VL, Fernandes, JC, Flor, LS, Foigt, NA, Forouzanfar, MH, Ganji, M, Geleijnse, JM, Gillum, RF, Goulart, AC, Grosso, G, Guessous, I, Hamidi, S, Hankey, GJ, Harikrishnan, S, Hassen, HY, Hay, SI, Hoang, CL, Horino, M, Islami, F, Jackson, MD, James, SL, Johansson, L, Jonas, JB, Kasaeian, A, Khader, YS, Khalil, IA, Khang, YH, Kimokoti, RW, Kokubo, Y, Kumar, GA, Lallukka, T, Lopez, AD, Lorkowski, S, Lotufo, PA, Lozano, R, Malekzadeh, R, März, W, Meier, T, Melaku, YA, Mendoza, W, Mensink, GBM, Micha, R, Miller, TR, Mirarefin, M, Mohan, V, Mokdad, AH, Mozaffarian, D, Nagel, G, Naghavi, M, Nguyen, CT, Nixon, MR, Ong, KL, Pereira, DM, Poustchi, H, Qorbani, M, Rai, RK, Razo-García, C, Rehm, CD, Rivera, JA, Rodríguez-Ramírez, S, Roshandel, G, Roth, GA, Sanabria, J, Afshin, A, Sur, PJ, Fay, KA, Cornaby, L, Ferrara, G, Salama, JS, Mullany, EC, Abate, KH, Abbafati, C, Abebe, Z, Afarideh, M, Aggarwal, A, Agrawal, S, Akinyemiju, T, Alahdab, F, Bacha, U, Bachman, VF, Badali, H, Badawi, A, Bensenor, IM, Bernabe, E, Biadgilign, SKK, Biryukov, SH, Cahill, LE, Carrero, JJ, Cercy, KM, Dandona, L, Dandona, R, Dang, AK, Degefa, MG, El Sayed Zaki, M, Esteghamati, A, Esteghamati, S, Fanzo, J, Farinha, CSES, Farvid, MS, Farzadfar, F, Feigin, VL, Fernandes, JC, Flor, LS, Foigt, NA, Forouzanfar, MH, Ganji, M, Geleijnse, JM, Gillum, RF, Goulart, AC, Grosso, G, Guessous, I, Hamidi, S, Hankey, GJ, Harikrishnan, S, Hassen, HY, Hay, SI, Hoang, CL, Horino, M, Islami, F, Jackson, MD, James, SL, Johansson, L, Jonas, JB, Kasaeian, A, Khader, YS, Khalil, IA, Khang, YH, Kimokoti, RW, Kokubo, Y, Kumar, GA, Lallukka, T, Lopez, AD, Lorkowski, S, Lotufo, PA, Lozano, R, Malekzadeh, R, März, W, Meier, T, Melaku, YA, Mendoza, W, Mensink, GBM, Micha, R, Miller, TR, Mirarefin, M, Mohan, V, Mokdad, AH, Mozaffarian, D, Nagel, G, Naghavi, M, Nguyen, CT, Nixon, MR, Ong, KL, Pereira, DM, Poustchi, H, Qorbani, M, Rai, RK, Razo-García, C, Rehm, CD, Rivera, JA, Rodríguez-Ramírez, S, Roshandel, G, Roth, GA, and Sanabria, J
- Abstract
Background: Suboptimal diet is an important preventable risk factor for non-communicable diseases (NCDs); however, its impact on the burden of NCDs has not been systematically evaluated. This study aimed to evaluate the consumption of major foods and nutrients across 195 countries and to quantify the impact of their suboptimal intake on NCD mortality and morbidity. Methods: By use of a comparative risk assessment approach, we estimated the proportion of disease-specific burden attributable to each dietary risk factor (also referred to as population attributable fraction)among adults aged 25 years or older. The main inputs to this analysis included the intake of each dietary factor, the effect size of the dietary factor on disease endpoint, and the level of intake associated with the lowest risk of mortality. Then, by use of disease-specific population attributable fractions, mortality, and disability-adjusted life-years (DALYs), we calculated the number of deaths and DALYs attributable to diet for each disease outcome. Findings: In 2017, 11 million (95% uncertainty interval [UI]10–12)deaths and 255 million (234–274)DALYs were attributable to dietary risk factors. High intake of sodium (3 million [1–5]deaths and 70 million [34–118]DALYs), low intake of whole grains (3 million [2–4]deaths and 82 million [59–109]DALYs), and low intake of fruits (2 million [1–4]deaths and 65 million [41–92]DALYs)were the leading dietary risk factors for deaths and DALYs globally and in many countries. Dietary data were from mixed sources and were not available for all countries, increasing the statistical uncertainty of our estimates. Interpretation: This study provides a comprehensive picture of the potential impact of suboptimal diet on NCD mortality and morbidity, highlighting the need for improving diet across nations. Our findings will inform implementation of evidence-based dietary interventions and provide a platform for evaluation of their impact on human health annually. Fundin
- Published
- 2019
50. Socioeconomic position, lifestyle habits and biomarkers of epigenetic aging: a multi-cohort analysis
- Author
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Fiorito, G, McCrory, C, Robinson, O, Carmeli, C, Rosales, CO, Zhang, Y, Colicino, E, Dugue, P-A, Artaud, F, Mckay, GJ, Jeong, A, Mishra, PP, Nost, TH, Krogh, V, Panico, S, Sacerdote, C, Tumino, R, Palli, D, Matullo, G, Guarrera, S, Gandini, M, Bochud, M, Dermitzakis, E, Muka, T, Schwartz, J, Vokonas, PS, Just, A, Hodge, AM, Giles, GG, Southey, MC, Hurme, MA, Young, I, McKnight, AJ, Kunze, S, Waldenberger, M, Peters, A, Schwettmann, L, Lund, E, Baccarelli, A, Milne, RL, Kenny, RA, Elbaz, A, Brenner, H, Kee, F, Voortman, T, Probst-Hensch, N, Lehtimaki, T, Elliot, P, Stringhini, S, Vineis, P, Polidoro, S, Alberts, J, Alenius, H, Avendano, M, Baltar, V, Bartley, M, Barros, H, Bellone, M, Berger, E, Blane, D, Candiani, G, Carra, L, Castagne, R, Chadeau-Hyam, M, Cima, S, Clavel-Chapelon, F, Costa, G, Courtin, E, Delpierre, C, D'Errico, A, Manolis, Dermitzakis, Elovainio, M, Elliott, P, Fagherazzi, G, Fraga, S, Gares, V, Gerbouin-Rerolle, P, Giles, G, Goldberg, M, Greco, D, Guessous, I, Haba-Rubio, J, Heinzer, R, Hodge, A, Joost, S, Karimi, M, Kelly-Irving, M, Kahonen, M, Karisola, P, Khenissi, L, Kivimaki, M, Laine, J, Lang, T, Laurent, A, Layte, R, Lepage, B, Lorsch, D, MacGuire, F, Machell, G, Mackenbach, J, Marmot, M, de Mestral, C, Miller, C, Milne, R, Muennig, P, Nusselder, W, Petrovic, D, Lourdes, Pilapil, Preisig, M, Pulkki-Raback, L, Raitakari, O, Ribeiro, AI, Ricceri, F, Recalcati, P, Reinhard, E, Valverde, JR, Saba, S, Santegoets, F, Satolli, R, Simmons, T, Severi, G, Shipley, MJ, Tabak, A, Terhi, V, Tieulent, J, Vaccarella, S, Vigna-Taglianti, F, Vollenweider, P, Vuilleumier, N, Zins, M, Fiorito, G, McCrory, C, Robinson, O, Carmeli, C, Rosales, CO, Zhang, Y, Colicino, E, Dugue, P-A, Artaud, F, Mckay, GJ, Jeong, A, Mishra, PP, Nost, TH, Krogh, V, Panico, S, Sacerdote, C, Tumino, R, Palli, D, Matullo, G, Guarrera, S, Gandini, M, Bochud, M, Dermitzakis, E, Muka, T, Schwartz, J, Vokonas, PS, Just, A, Hodge, AM, Giles, GG, Southey, MC, Hurme, MA, Young, I, McKnight, AJ, Kunze, S, Waldenberger, M, Peters, A, Schwettmann, L, Lund, E, Baccarelli, A, Milne, RL, Kenny, RA, Elbaz, A, Brenner, H, Kee, F, Voortman, T, Probst-Hensch, N, Lehtimaki, T, Elliot, P, Stringhini, S, Vineis, P, Polidoro, S, Alberts, J, Alenius, H, Avendano, M, Baltar, V, Bartley, M, Barros, H, Bellone, M, Berger, E, Blane, D, Candiani, G, Carra, L, Castagne, R, Chadeau-Hyam, M, Cima, S, Clavel-Chapelon, F, Costa, G, Courtin, E, Delpierre, C, D'Errico, A, Manolis, Dermitzakis, Elovainio, M, Elliott, P, Fagherazzi, G, Fraga, S, Gares, V, Gerbouin-Rerolle, P, Giles, G, Goldberg, M, Greco, D, Guessous, I, Haba-Rubio, J, Heinzer, R, Hodge, A, Joost, S, Karimi, M, Kelly-Irving, M, Kahonen, M, Karisola, P, Khenissi, L, Kivimaki, M, Laine, J, Lang, T, Laurent, A, Layte, R, Lepage, B, Lorsch, D, MacGuire, F, Machell, G, Mackenbach, J, Marmot, M, de Mestral, C, Miller, C, Milne, R, Muennig, P, Nusselder, W, Petrovic, D, Lourdes, Pilapil, Preisig, M, Pulkki-Raback, L, Raitakari, O, Ribeiro, AI, Ricceri, F, Recalcati, P, Reinhard, E, Valverde, JR, Saba, S, Santegoets, F, Satolli, R, Simmons, T, Severi, G, Shipley, MJ, Tabak, A, Terhi, V, Tieulent, J, Vaccarella, S, Vigna-Taglianti, F, Vollenweider, P, Vuilleumier, N, and Zins, M
- Abstract
Differences in health status by socioeconomic position (SEP) tend to be more evident at older ages, suggesting the involvement of a biological mechanism responsive to the accumulation of deleterious exposures across the lifespan. DNA methylation (DNAm) has been proposed as a biomarker of biological aging that conserves memory of endogenous and exogenous stress during life.We examined the association of education level, as an indicator of SEP, and lifestyle-related variables with four biomarkers of age-dependent DNAm dysregulation: the total number of stochastic epigenetic mutations (SEMs) and three epigenetic clocks (Horvath, Hannum and Levine), in 18 cohorts spanning 12 countries.The four biological aging biomarkers were associated with education and different sets of risk factors independently, and the magnitude of the effects differed depending on the biomarker and the predictor. On average, the effect of low education on epigenetic aging was comparable with those of other lifestyle-related risk factors (obesity, alcohol intake), with the exception of smoking, which had a significantly stronger effect.Our study shows that low education is an independent predictor of accelerated biological (epigenetic) aging and that epigenetic clocks appear to be good candidates for disentangling the biological pathways underlying social inequalities in healthy aging and longevity.
- Published
- 2019
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