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Background Chronic inflammation persists in some people living with human immunodeficiency virus (HIV) during antiretroviral therapy and is associated with premature aging. The glycoprotein 120 (gp120) subunit of HIV-1 envelope sheds and can be detected in plasma, showing immunomodulatory properties even in the absence of detectable viremia. We evaluated whether plasma soluble gp120 (sgp120) and a family of gp120-specific anti–cluster A antibodies, linked to CD4 depletion in vitro, contribute to chronic inflammation, immune dysfunction, and subclinical cardiovascular disease in participants of the Canadian HIV and Aging Cohort Study with undetectable viremia. Methods Cross-sectional assessment of sgp120 and anti–cluster A antibodies was performed in 386 individuals from the cohort. Their association with proinflammatory cytokines and subclinical coronary artery disease was assessed using linear regression models. Results High levels of sgp120 and anti–cluster A antibodies were inversely correlated with CD4+ T cell count and CD4/CD8 ratio. The presence of sgp120 was associated with increased levels of interleukin 6. In participants with detectable atherosclerotic plaque and detectable sgp120, anti–cluster A antibodies and their combination with sgp120 levels correlated positively with the total volume of atherosclerotic plaques. Conclusions This study showed that sgp120 may act as a pan toxin causing immune dysfunction and sustained inflammation in a subset of people living with HIV, contributing to the development of premature comorbid conditions. [ABSTRACT FROM AUTHOR]

In this study, we examined the effects of body-focused daily self-compassion and self-esteem expressive writing activities on women's valuation of weight management goals, body appreciation, bulimic symptoms, and healthy and unhealthy eating behaviors. One-hundred twenty-six women, recruited from the community and a university participant pool (M age = 29.3, SD = 13.6), were randomly allocated to one of the three writing conditions: body-focused self-compassion, body-focused self-esteem, or control. Women reflected on a moment within the past 24 hours that made them feel self-conscious about their bodies, eating, or exercise habits (self-compassion and self-esteem conditions) or on a particular situation or feeling that occurred in the past 24 hours (control condition) for 4–7 days. At post-treatment (24 hours after the intervention), women in the self-compassion group demonstrated decreased bulimic symptoms, while women in the self-esteem and control conditions did not. Furthermore, clinically significant changes in bulimic symptoms were associated with being in the self-compassion condition but not in the self-esteem or control conditions. Results suggest that body-focused writing interventions may be more effective in temporarily reducing eating disorder symptoms in women if they focus on harnessing self-compassion. Additional online materials for this article are available on PWQ 's website at http://journals.sagepub.com/doi/suppl/10.1177/03616843211013465 [ABSTRACT FROM AUTHOR]

This study examined whether pursuing intrinsic versus extrinsic goals was associated with distinct motivational processes in eating regulation and with healthy versus unhealthy eating. Path analysis demonstrated that appearance goals were associated with fat talk, whereas health goals were associated with self-compassion. Fat talk was positively associated with non-self-determined motivation and unhealthy eating, whereas self-compassion was positively associated with self-determined motivation and healthy eating, and negatively associated with unhealthy eating. Findings emphasize the negative effects of pursuing appearance goals and engaging in fat talk and the benefits of pursuing health goals and being self-compassionate. [ABSTRACT FROM AUTHOR]

We report on the development, the adaptation, the validation, and the utility of the French version of the revised Sport Motivation Scale (SMS-II), namely the EMS-II (Échelle de Motivation dans les Sports), a scale developed originally in English to measure the six motivation subtypes (intrinsic motivation, integrated, identified, introjected, and external regulation of extrinsic motivation, and amotivation) proposed by self-determination theory (SDT). Results from two studies with athletes (N = 506) from different sports indicated that the scale has good psychometric properties. Specifically, the results of the confirmatory factor analysis suggest that the scale holds an adequate structure consistent with the six types of motivation proposed by SDT, and that French and English athletes were invariant with regard to the structure of the six-factor scale. The results also indicated that the scale had sufficient discriminant and convergent validity, and Cronbach's alpha suggests that all subscales have adequate internal consistency. Finally, correlations between the subscales suggest evidence of a simplex pattern, which support the self-determination continuum within the SDT framework. Direction for future research and conceptual implications are discussed. [ABSTRACT FROM AUTHOR]

Health promotion programs represent a salient means through which physical activity promoters can cultivate positive health behavior change and maintenance. The messages communicated within these programs serve as an essential component as they are often used to convey valuable information, resources, or tools that facilitate health behavior initiation and sustained engagement. Identifying the most effective way to communicate health promotion information is, therefore, of considerable importance to ensuring that people not only attend to these messages, but also connect with and internalize the information conveyed within them. This paper was written to (1) summarize and evaluate the most prominent reviewed research approaches of message framing and tailoring to message design; and (2) offer a comprehensive messaging strategy to promote sustained health behavior change. A review of the literature demonstrated that a messaging strategy that has consistently led to healthy behavior change has yet to be identified. Furthermore, scholars have articulated that a multi-theoretical approach that places emphasis on facilitating motivation and healthy behavior change needs to be employed. Thus, this paper proposes and provides recommendations for employing the Comprehensive Messaging Strategy for Sustained Behavior Change (CMSSBC), which advocates tailoring messages to peoples’ stage of change and framing them to focus on self-determined motives and intrinsic goals. [ABSTRACT FROM AUTHOR]

This research examined if planning and self-monitoring could be distinguished in terms of quality and quantity, and if differences in the uses of these strategies were associated with distinct eating outcomes. In Study 1 (n = 355), the structure of a new scale designed to measure planning and self-monitoring in terms of quality (i.e., nutrient intake) and quantity (i.e., calories and portion sizes) was examined through Confirmatory Factor Analysis. Structural equation models were also tested in which the relationships between the proposed strategies, healthy and unhealthy eating behaviors and bulimic symptoms, as well as BMI, were examined. The purpose of Study 2 (n = 318) was to replicate the results found in Study 1, using a different sample. Overall, a 6-factor structure was found for the scale and results revealed that strategies related to the quality of eating were more strongly and positively associated with healthy eating and more strongly and negatively associated with unhealthy eating behaviors, whereas strategies related to the quantity of eating were more strongly and positively associated with bulimic symptoms and BMI. Results are discussed in terms of implications for health professionals who wish to improve individuals' eating behaviors and/or weight. [ABSTRACT FROM AUTHOR]