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7. Time perspective and amnestic mild cognitive impairment

Author

Coelho, Sara, de Mendonça, Alexandre, Maroco, João, Cardoso, Sandra, Mello, Zena, and Guerreiro, Manuela

Subjects
Clinical and Health Psychology, Psychology, Behavioral and Social Science, Mental Health, Clinical Research, Mental health, Aged, Amnesia, Cognitive Dysfunction, Executive Function, Humans, Neuropsychological Tests, Time Perception, Memory, Cognitive Decline, Executive Functions, Time Orientation, Time Relation, Time Perspective, Medical and Health Sciences, Psychology and Cognitive Sciences, Experimental Psychology, Clinical sciences, Neurosciences, Biological psychology
Abstract

ObjectiveWe examined time perspective in patients with amnesic mild cognitive impairment (aMCI). Prior research has shown that aMCI is associated with difficulties in experiencing time duration and succession. However, this line of inquiry has not been extended to time perspective. We examined associations between aMCI and multiple dimensions of time perspective including perceived orientations and relationships among the past, present, and future.MethodThirty aMCI patients and thirty-three healthy controls participated. Measures were the Time Orientation Scale (TOS), the Time Relation Scale (TRS), and the Zimbardo Time Perspective Inventory (ZTPI), as well as a comprehensive neuropsychological evaluation.ResultsThe TRS was associated with aMCI. Patients with aMCI were more likely to perceive that time was unrelated than the healthy older adults. Among patients with aMCI, an unrelated time perspective was associated with poorer performance in executive function measures. However, aMCI was not associated with the TOS or the ZTPI.ConclusionsPatients with aMCI have difficulty in perceiving relationships among the past, present, and future. This could be the consequence of deficits in executive functions. This research suggests that patients with aMCI may have limited understanding for how their current behaviours are related to both their past and future.

Published
2022

10. Creative Tourism

Author

Guerreiro, Manuela, Dieke, Peter U. C., Section editor, Jafari, Jafar, editor, and Xiao, Honggen, editor

Published
2024
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11. Ensemble learning with Conformal Predictors: Targeting credible predictions of conversion from Mild Cognitive Impairment to Alzheimer's Disease

Author

Pereira, Telma, Cardoso, Sandra, Silva, Dina, Guerreiro, Manuela, de Mendonça, Alexandre, and Madeira, Sara C.

Subjects
Computer Science - Machine Learning, Statistics - Machine Learning
Abstract

Most machine learning classifiers give predictions for new examples accurately, yet without indicating how trustworthy predictions are. In the medical domain, this hampers their integration in decision support systems, which could be useful in the clinical practice. We use a supervised learning approach that combines Ensemble learning with Conformal Predictors to predict conversion from Mild Cognitive Impairment to Alzheimer's Disease. Our goal is to enhance the classification performance (Ensemble learning) and complement each prediction with a measure of credibility (Conformal Predictors). Our results showed the superiority of the proposed approach over a similar ensemble framework with standard classifiers., Comment: 4 pages, 1 figure, accepted for presentation at the KDD Workshop on Machine Learning for Medicine and Healthcare, London, UK, August 2018

Published
2018

14. From Tourist Experience to Satisfaction and Loyalty: Exploring the Role of a Sense of Well-Being.

Author

Bagheri, Fatemeh, Guerreiro, Manuela, Pinto, Patrícia, and Ghaderi, Zahed

Subjects
*EXPLORATORY factor analysis, *STRUCTURAL equation modeling, *SATISFACTION, *WELL-being, *SCALING (Social sciences), *LOYALTY, *TOURIST attitudes, *HAPPINESS
Abstract

Drawing on the authentic happiness theory, the aims of this article are three-fold: first, to propose a refined measurement scale for tourists' sense of well-being; second, to investigate the impact of four categories of tourist experience on tourists' sense of well-being; and third, to explore the effect of the sense of well-being on tourists' satisfaction and loyalty. Data were collected from tourists spending their holidays in the Algarve, Portugal. To address the lack of an integrated measurement scale for assessing tourists' sense of well-being, an exploratory factor analysis was initially conducted. Subsequently, the data were analyzed using structural equation modeling in WarpPLS 8.0. The findings reveal a three-dimensional scale for tourists' sense of well-being, consisting of meaningfulness, active pleasure, and release. The results also show a significant positive impact of the four realms of tourists' experiences on the sense of well-being. Finally, positive relationships between well-being, tourist satisfaction and loyalty are confirmed. The theoretical and practical implications, limitations, and potential directions for future research are discussed. [ABSTRACT FROM AUTHOR]

Published
2024
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15. Impact of Neuropsychological Assessment on Subjective Memory Complaints in Patients With Mild Cognitive Impairment.

Author

Anjos, Ricardo, Madruga, Nuno, Cardoso, Sandra, Schmand, Ben, Guerreiro, Manuela, de Mendonça, Alexandre, and Ribeiro, Filipa

Subjects
ALZHEIMER'S disease, EXECUTIVE function, COGNITION disorders, NEUROPSYCHOLOGICAL tests, CASE-control method, MEMORY disorders, MENTAL depression, DISEASE complications
Abstract

Introduction: Patients with Alzheimer's disease (AD), namely at an initial stage like amnestic cognitive impairment (aMCI), typically present with memory complaints. They also have difficulties regarding self‐knowledge about their cognitive deficits. In clinical practice, a formal neuropsychological assessment is often done. The present study aimed to understand whether patients with aMCI retain the ability to monitor the success or failure in their performance during the neuropsychological assessment and adjust the report of memory complaints accordingly, as compared to healthy controls. Methods: Participants were patients with aMCI and healthy controls who were questioned about their own memory abilities using the Subjective Memory Complaints (SMC) scale, applied before and after the neuropsychological assessment protocol. A repeated measures General Linear Model was performed to analyze changes in SMC (within‐subjects effects) after the neuropsychological assessment, in patients with aMCI and healthy controls (between‐subjects effects). Results: Eighty volunteers, 40 patients with aMCI and 40 healthy controls, participated in the study. Patients with aMCI showed lower MMSE scores, more depressive symptoms, and deficits in memory and learning, language and executive domains. Patients with aMCI had higher SMC scores [9.4(3.6)] than healthy controls [4.4(2.3)] before the neuropsychological assessment. A statistically significant interaction was found between the SMC and the diagnostic group, meaning that healthy controls decreased SMC [3.4(1.9)] after the neuropsychological assessment, whereas patients with aMCI kept high levels of SMC [9.6(3.9)]. In patients with aMCI, an inverse correlation between logical memory and the change in SMC was found, so that patients with lower scores in the logical memory test tended to increase their memory complaints after the assessment. Conclusions: Both patients with aMCI and healthy controls can monitor and update the impression about their memory abilities following a formal neuropsychological assessment. Patients with aMCI maintain a high SMC level, which is inversely associated with their memory performance. In practical terms, SMC should be measured consistently at a particular moment in time, preferably preceding the objective neuropsychological assessment. [ABSTRACT FROM AUTHOR]

Published
2024
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18. Building bridges between residents and tourism: Attitudinal support, emotional solidarity, and intentions for pro-tourism behaviours.

Author

Lança, Milene, Pereira, Luís Nobre, Renda, Ana Isabel, Pinto, Patrícia, Marques, João Filipe, Ramos, Célia, Guerreiro, Manuela, and Lai, Hio Kuan

Subjects
SOCIAL exchange, THEORY of reasoned action, STRUCTURAL equation modeling, PERCEIVED benefit, SOCIAL influence
Abstract

Copyright of Tourism & Management Studies is the property of Escola Superior de Gestao, Hotelaria e Turismo, Universidade do Algarve and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2024
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19. The online destination image as portrayed by the user-generated content on social media and its impact on tourists' engagement.

Author

Guerreiro, Manuela, Pinto, Patrícia, Ramos, Célia M. Q., Matos, Nelson, Golestaneh, Homayoun, Sequeira, Bernardete, Pereira, Luís Nobre, Agapito, Dora, Martins, Rafaela, and Wijkesjö, Magda

Subjects
USER-generated content, SENTIMENT analysis, SOCIAL media, TOURIST attractions, IMAGE analysis, TOURISTS, DESTINATION image (Tourism)
Abstract

Copyright of Tourism & Management Studies is the property of Escola Superior de Gestao, Hotelaria e Turismo, Universidade do Algarve and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2024
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20. Amyloid-Negative, Neurodegeneration-Negative Amnestic Mild Cognitive Impairment.

Author

Cardoso, Sandra, Guerreiro, Manuela, Montalvo, Alexandre, Silva, Dina, Alves, Luísa, and de Mendonça, Alexandre

Subjects
*AMNESTIC mild cognitive impairment, *GERIATRIC Depression Scale, *ALZHEIMER'S disease, *COGNITIVE testing, *NEUROPSYCHOLOGICAL tests
Abstract

Background: The concept of amnestic mild cognitive impairment (aMCI) was developed to identify patients at an initial stage of Alzheimer's disease (AD). However, some patients with aMCI do not present biomarkers of amyloid pathology or neuronal injury. Objective: To know the natural history of amyloid-negative and neurodegeneration-negative patients with aMCI, namely to ascertain: 1) whether these patients remain cognitively stable or they present a slow decline in neuropsychological tests; 2) whether the memory complaints subside with the apparently benign clinical course of the disorder or if they persist along the time. Methods: Patients who fulfilled criteria for aMCI with no biomarkers of amyloid pathology or neuronal injury were selected from a large cohort of non-demented patients with cognitive complaints, and were followed with clinical and neuropsychological assessments. Results: Twenty-one amyloid-negative and neurodegeneration-negative aMCI patients were followed for 7.1±3.7 years. At the baseline they had more pronounced deficits in verbal learning (California Verbal Learning Test) and were also impaired in Word Recall and Logical Memory. However, they did not decline in any cognitive test during follow-up. The patients maintained a high level of subjective memory complaints from baseline (9.7±4.1) to the follow-up visit (9.2±4.1, a non-significant difference), in spite of a statistically significant decrease in the depressive symptoms, with Geriatric Depression Scale (15 items) score 4.9±2.8 at baseline and 3.2±1.8 at the follow-up visit. Conclusions: Amyloid-negative, neurodegeneration-negative aMCI is a chronic clinical condition characterized by the long-term persistence of cognitive deficits and distressing memory complaints. Adequate strategies to treat this condition are needed. [ABSTRACT FROM AUTHOR]

Published
2024
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24. SAÚDE MENTAL - VOLUME 1

Author

Santos, Aline Neli Dos, primary, Ferreira, Verônica Moreira Souto, additional, Ribeiro, Adriano Diego Oliveira, additional, Pacheco, Lucas Gama, additional, Santos, Rayssa Marise Da Costa Dos, additional, Oliveira, Aline Da Silva, additional, Oliveira, Eliany Nazaré, additional, Santos, Ludmilla Alves, additional, Maciel, Jacques Antonio Cavalcante, additional, Pereira, Paulo Almeida, additional, Almeida, Paulo Cesar De, additional, Vasconcelos, Maristela Inês Osawa, additional, X, Francisco R G, additional, Lima, Gleisson Ferreira, additional, Campos, Marcos Pires, additional, Lima, Danyela Dos Santos, additional, Aragão, Helianda Linhares, additional, França, Sabrina Da Silva, additional, Melo, Francisca Verônica Dias, additional, Freire, Magda Almeida, additional, Ximenes, Francisco Rosemiro Guimarães, additional, Almeida, Paulo César De, additional, Freire, Marcela Almeida, additional, Lima, Gleisson Ferrera, additional, Viana, Lorenna Saraiva, additional, Rodrigues, Caio San, additional, Silva, Emília Do Nascimento, additional, Silva, Lídia Cristina Monteiro Da, additional, Andrade, Carla Suyane Gomes De, additional, Costa, João Breno Cavalcante, additional, Costa, Silvinha De Sousa, additional, Sousa, Antônia Márcia Macêdo De, additional, Feijó, Ivan Gabriel Sousa, additional, Nascimento, Ravena Silva Do, additional, Lima, Letícia Mara Cavalcante, additional, Fernandes, Márcia A, additional, Melo, Cris Aragão, additional, Feitosa, Lucíola Galvão Gondim Corrêa, additional, Ribeiro, Ivonizete Pires, additional, Tapety, Fabrício Ibiapina, additional, Ribeiro, Amanda Alves de Alencar, additional, Fernandes, Márcia Astrês, additional, Pillon, Sandra Cristina, additional, Rocha, Eukália Pereira da, additional, Ribeiro, Amanda Alves De Alencar, additional, Feitosa, Carla Danielle Araújo, additional, Rocha, Daniel de Macêdo, additional, Lima, Larissa Alves de Araújo, additional, Oliveira, Ana Lívia Castelo Branco de, additional, Monteiro, Claudete Ferreira de Souza, additional, Rocha, Daniel De Macêdo, additional, Olinda, Krieger Rhelyni De Sousa, additional, Oliveira, Aline Costa De, additional, Vasconcelos, Claudia Daniella Avelino, additional, Sousa, Ivana Cavalcante Lemos De, additional, Nogueira, Lídya Tolstenko, additional, Batista, Matheus Neres, additional, Silveira, Keiscielly Assunção Faria, additional, Brito, Renata Cristina Vieira De, additional, Santos, Jehovahnna Anttonioni, additional, Puglia, Ana C, additional, Pinheiro, Elisama Pereira, additional, Peres, Camila Luíza, additional, Rios, Marcella Maciel, additional, Gomes, Pedro Vinícius Teles, additional, Carvalho, Lanna C, additional, S, Joel A, additional, Veloso, Eliana A N, additional, Zaibak, Carla Azevedo, additional, Gonçalves, Amanda Carolina de Melo, additional, Dias, Karolinne Dorneles, additional, Gonçalves, Rafael Salles de Melo, additional, Freitas, Marcos Vinícios De, additional, Franke, Djonathan Daniel, additional, Puglia, Ana Clara, additional, Carvalho, Lanna do Carmo, additional, Sousa, Joel Alves De, additional, Veloso, Eliana Almeida Naves, additional, Gonçalves, Amanda Carolina De Melo, additional, Gonçalves, Rafael Salles De Melo, additional, Souza, Vitor Santos de, additional, Faria, Bárbara Caroline Dias, additional, Sacramento, Luiz Gustavo Guimarães, additional, Oliveira, Nathália Cristian Ferreira de, additional, Goll, Yan Lopes, additional, Souza, Camila Alencar Monteiro de, additional, Costa, Grace Ellen Pereira, additional, Soares, Ana Cecilia Cardozo, additional, Alves, Rita De Cássia Loiola, additional, Manoel, Poliana Zanotto, additional, Bezerra, Vinícius Grangeiro Leite, additional, Maciel, Nathanael De Souza, additional, Nascimento, Cidianna Emanuelly Melo do, additional, Dias, Maria Fernanda Figueiredo Lanza, additional, Bretas, Amanda Duarte, additional, Fernandes, Fernanda Pimenta, additional, Ferreira, Amanda Cambraia, additional, França, Jéssica Helena Souza de, additional, Santos, Tatiane Lima, additional, Oliveira, Miriam Souza, additional, Monteiro, Ana Paula Monteiro E, additional, Silva, Danielle Oliveira Da, additional, Silva, David Alfredo Cordeiro Da, additional, Pantoja, Gylmara Melo, additional, Matos, Isabela Ceres Da Silva, additional, Nascimento, Josilene Santana Do, additional, Lopes, Kézia Dias, additional, Silva, Lucas Eduardo Silva E, additional, Silva, Lucimara Ribeiro Da, additional, Pantoja, Marcela Thaíse Machado, additional, Mendes, Mayara Pinheiro, additional, Freitas, Thamires Cabral, additional, Guimarães, Victória Lima, additional, Lins, Ana Carolina Araújo De Almeida, additional, Winter, Marcella Lourenço, additional, Ribeiro, Christiane Carvalho, additional, Siqueira-, Thayane Santos, additional, Dias, Andrielly Késia Santos, additional, Celestino, Ariel Almeida, additional, Souza, Mariana Do Rosário, additional, Santos, Alexrangel Henrique Cruz, additional, Santos, Beatriz Almeida, additional, Melo, Ítalo Fernando Lisboa De, additional, Barbosa, Luciene, additional, Silva, Cindy Menezes, additional, Marinho, Déborah Danielly Tertuliano, additional, Rodrigues, Priscylla Frazão, additional, Fonseca, Olívio Joaquim, additional, Barbosa, João Victor Carvalho, additional, Ferraz, Isabella Cabral, additional, Lima, Cláudio Vinícius Barroso Queirós de, additional, Souza, Pedro Henrique De, additional, Lins, Raphaela da Penha, additional, Silva, Ronaldo de Ataide Nicácio, additional, Passos, Evelyn Amorim Dias, additional, Segundo, Manoel Pedro de Farias, additional, Silva, Ellen Dayanne Barros, additional, Melo, Guilherme Silva De, additional, Oliveira, Nathália Lopes De, additional, Santos, Nadilly Sobral Monteiro Dos, additional, Lopes, Carla Carolina Alves, additional, Castro, Beatriz Pellegrini, additional, Paula, Camila da Costa, additional, Cupertino, Gabriel Buffon, additional, Paula, Larissa Ottoni Estevanin de, additional, Sanna, Isabela Pimenta, additional, Andrade, Leonardo Isolani e, additional, Oliveira, Paulo José Soares André, additional, Souza, Tamara Rodrigues Fonseca, additional, Diniz, Rhodolfo Campos Siqueira, additional, Simão, Juliana Santos, additional, Santos, Daniel Coutinho dos, additional, Souza, Daianne Santos de, additional, Rocha, Antônia Marcela Silva, additional, Sousa, Sara Bernarda Moreira de, additional, Feitosa, Marcela de Oliveira, additional, Campos, Douglas Moraes, additional, Nunes, Sabrina Freitas, additional, Siqueira, Lucas De Carvalho, additional, Santos, Bárbara Thaís Souza Dos, additional, anna, Inaê Lima Machado Vaccari Sant, additional, Corrêa, Sabrina Elora De Almeida, additional, Oliveira, Samilly Sousa De, additional, Almeida, Sandy Siqueira De Alencar, additional, Nascimento, Cidianna Emanuelly Melo Do, additional, Anjos, Hannah Barbosa Lopes dos, additional, Dutra, Carolina Nunes, additional, Rocha, Ana Luisa de Oliveira, additional, Silva, Breno Henrique Colares, additional, Rossati, Luaan Silva, additional, Gomes, Luiza Pedrosa, additional, Bernardes, Maria Eduarda Cunha, additional, Costa, Suellen Cristine, additional, Nunes, Cristiana Buzelin, additional, Saldanha, Janaína Cláudia da Silva, additional, Ferreira, Lívia Bonin, additional, Rocha, Lara Aliprandi, additional, Horsth, Enzo Boecher, additional, Sepúlvida, Cindy Sicylia Damm, additional, Marques, Eduardo Casella, additional, Padilha, Luisa Colnaghi, additional, Souza, Carlos Eduardo Favoretti De, additional, Araújo, Vitória Gabriele Barros de, additional, Costa, Jorgyanne Gonzalez, additional, Silva, Bárbara Leite da, additional, Fonsêca, Alana Meneses Leal, additional, Silva, João Victor Vieira De Brito, additional, Nascimento, Alice Benicio Do, additional, Reis, Maria Clara Gomes Dos, additional, Souza, Ana Paula De Carvalho, additional, Moraes, Ramires dos Santos, additional, Alves, Nágila Silva, additional, Schmitt, Layne Mendonça, additional, Souza, Esther Cardoso Dos Santos, additional, Silva, Carolina Bragança E, additional, Pereira, Iargram Leite, additional, Léon, Lucas Caldas, additional, Sobrinho, Weberton Dorásio, additional, Estrela, Matheus Rodrigues De Araújo, additional, Albuquerque, Ana Carolina Tocantins, additional, Maia, Lucas Lafaerto Felix, additional, Freitas, Gabriel Barcelos De, additional, Nassaralla, Anna Paula Amaral, additional, Costa, Yana Maílla Pamplona, additional, Dutra, Paulo Vitor Carvalho, additional, Daher, Luís Guilherme Rassi Mahamed, additional, Braga, Talita, additional, Pires, Carlos Henrique Nunes, additional, Sousa, Miriam Elayne Macêdo de, additional, Araujo, Milena Thaisa Rodrigues De, additional, Gomes, Laisa Fernanda Dos Anjos, additional, Freitas, Thayanne Sousa De, additional, Moraes, Israele Paz De, additional, Araújo, Débora Virgínia Castelo Branco Sales, additional, Silva, Márcia De Sousa, additional, Silva, Jordeilson Luis Araújo, additional, Teixeira, Natalia Da Silva, additional, Silva, Emylla De Sousa, additional, Araújo, Welber Silva, additional, Niza, Vitória Freitas, additional, Rocha, Carolina Luzia Barcelos, additional, Isaac, Yasmin Bulkool, additional, Pereira, Juliana Tome, additional, Tracz, Rita, additional, Gonçalves, Ana Flávia, additional, Bosca, Luana Lima, additional, Matos, Taisa Caroline Metring De, additional, Marcovicz, Gabriele De Vargas, additional, Pereira, Larissa Rezende Lima, additional, OLIVEIRA, MAYRA LOURES DE, additional, Siqueira, André Luis Ferreira, additional, Paiva, Caique Pereira De, additional, Louzada, Carlos Eduardo Corrêa, additional, Dutra, Débora Ribeiro, additional, Nascimento, Jonas Eduardo Do Prado, additional, Parolis, Júlia Alves De, additional, Silva, Laion Roberto Ferreira Da, additional, Guerra, Lívia Pierazoli De Carvalho, additional, Guerreiro, Manuela Moreira, additional, Ferreira, Maria Mariana Abras, additional, Nogueira, Pedro Henrique Fonseca, additional, Blasi, Sérgio Ítalo, additional, Carvalho, Stefânia Maria Magalhães De, additional, Oliveira, Mayra Loures De, additional, Malta, Agda Louise Cardoso, additional, Ribeiro, Andressa Oliveira, additional, Martins, Emilly Andrade, additional, Vieira, Gabriela Berchiol, additional, Kneip, Izabella De Castro Cabral, additional, Soares, Júlia Pereira, additional, Quintana, Larissa Martins, additional, Albano, Leonardo Galvão, additional, Rodrigues, Letícia Castro De Souza, additional, Lima, Mariane Merched, additional, Souza, Mikaelly Faria De, additional, Barbosa, Rhaimei Izorai Gonçalves, additional, Cerqueira, Yara Martins, additional, Cruz, Mateus Ibiapina Vaz de Sousa, additional, Vieira, Ingrid Raquel Lima, additional, ROCHA, EUKÁLIA PEREIRA, additional, Sousa, Tainan Mourão De, additional, Abreu, Karen Beatriz Oliveira De, additional, Passos, Bruna Victoria da Silva, additional, Correia, Maria Eduarda Pereira, additional, Oliveira, Douglas Vieira de, additional, Leite, Wellington Macêdo, additional, Passos, Bruna Victória Da Silva, additional, VIEIRA, INGRID RAQUEL LIMA, additional, Rocha, Eukália Pereira Da, additional, Oliveira, Douglas Vieira De, additional, LEITE, WELLINGTON MACÊDO, additional, Fé, Roberta Cristina Gomes Franco Moura, additional, Lago, Eliana Campêlo, additional, Ramos, Carmen Viana, additional, Santiago, Antonio de Pádua Gandra, additional, Avelar, Lara Chierici, additional, Rodrigues, Arthur Campos Lima, additional, Pereira, Clara Bersemann Gontijo, additional, Soares, Arthur Mendes de Miranda, additional, Côrtes, Júlia Vieira Ferreira, additional, Lima, Alexya Caroline Delmonte, additional, Ferraresso, Carolina Kobbaz, additional, Viana, Matheus Santos, additional, Rocha, Tales Vilela, additional, Silvério, Alessandra Dos Santos Danzinger, additional, Ferreira, Bruna Mesquita Campos, additional, Castro, Igor Gonçalves, additional, Silva, Julia Carvalho, additional, Diniz, Letícia Dos Santos, additional, Lacerda, Lívia Dos Santos Abreu, additional, Costa, Maria Gabriela, additional, Ávila, Tamíris Silva, additional, Faria, Bruno Damaceno De, additional, Costa, Ana Luísa Mendes Pinheiro, additional, Guimarães, Luísa Prado, additional, Fernandes, Thalita Baptisteli, additional, Apolinário, Joelma Maria dos Santos da Silva, additional, and Ananias, Luana Maria Apolinário, additional

Published
2021
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25. Different MMSE domains are associated to cognitive decline and education.

Author

Cardoso, Sandra, Barros, Ricardo, Marôco, João, de Mendonça, Alexandre, and Guerreiro, Manuela

Subjects
MILD cognitive impairment, MINI-Mental State Examination, COGNITION, COGNITION disorders, DEMENTIA patients
Abstract

The Mini-Mental State Examination (MMSE) is a long-established test to screen for dementia, estimate the severity and monitor the progression of cognitive impairment. The MMSE total score is dependent upon demographic factors, particularly education, but little is known about how education influences the 6 distinct MMSE cognitive domains. The present study aims to understand how the performances in the MMSE cognitive domains reflect clinical diagnosis and educational level. The study recruited 1043 participants, comprising 388 healthy controls, 360 patients with Mild Cognitive Impairment (MCI) and 295 patients with dementia. The association of the MMSE cognitive domains scores with clinical diagnosis (healthy, MCI, dementia) and educational level (primary education, middle school, high school and university/college) was analyzed with a multivariate ordinal regression model. The scores in all MMSE domains were generally higher in healthy controls as compared to patients with MCI, and higher in these as compared to patients with dementia. The MMSE domain Constructional ability was associated to the education level, the domains Orientation, Recall and Language were associated to diagnosis, Attention and calculation was associated to both education level and diagnosis, and Registration was not associated to either education or diagnosis. In conclusion, impairment in specific MMSE domains pinpoints cognitive decline, probably indicating brain areas affected by neurodegeneration, and impairment in others reflects lower education levels and the lack of acquisition of relevant schooling abilities. [ABSTRACT FROM AUTHOR]

Published
2024
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28. Improving Prognostic Prediction from Mild Cognitive Impairment to Alzheimer’s Disease Using Genetic Algorithms

Author

Ferreira, Francisco L., Cardoso, Sandra, Silva, Dina, Guerreiro, Manuela, de Mendonça, Alexandre, Madeira, Sara C., Kacprzyk, Janusz, Series editor, Pal, Nikhil R., Advisory editor, Bello Perez, Rafael, Advisory editor, Corchado, Emilio S., Advisory editor, Hagras, Hani, Advisory editor, Kóczy, László T., Advisory editor, Kreinovich, Vladik, Advisory editor, Lin, Chin-Teng, Advisory editor, Lu, Jie, Advisory editor, Melin, Patricia, Advisory editor, Nedjah, Nadia, Advisory editor, Nguyen, Ngoc Thanh, Advisory editor, Wang, Jun, Advisory editor, Fdez-Riverola, Florentino, editor, Mohamad, Mohd Saberi, editor, Rocha, Miguel, editor, De Paz, Juan F., editor, and Pinto, Tiago, editor

Published
2017
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29. Towards Trustworthy Predictions of Conversion from Mild Cognitive Impairment to Dementia: A Conformal Prediction Approach

Author

Pereira, Telma, Cardoso, Sandra, Silva, Dina, de Mendonça, Alexandre, Guerreiro, Manuela, Madeira, Sara C., Kacprzyk, Janusz, Series editor, Pal, Nikhil R., Advisory editor, Bello Perez, Rafael, Advisory editor, Corchado, Emilio S., Advisory editor, Hagras, Hani, Advisory editor, Kóczy, László T., Advisory editor, Kreinovich, Vladik, Advisory editor, Lin, Chin-Teng, Advisory editor, Lu, Jie, Advisory editor, Melin, Patricia, Advisory editor, Nedjah, Nadia, Advisory editor, Nguyen, Ngoc Thanh, Advisory editor, Wang, Jun, Advisory editor, Fdez-Riverola, Florentino, editor, Mohamad, Mohd Saberi, editor, Rocha, Miguel, editor, De Paz, Juan F., editor, and Pinto, Tiago, editor

Published
2017
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32. Overtourism

Author

Carvalho, Fatima Lampreia, primary, Guerreiro, Manuela, additional, and Matos, Nelson, additional

Published
2020
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35. Sensory experiences in heritage contexts: A qualitative approach.

Author

Bender, Ana, Guerreiro, Manuela, Agapito, Dora, Dias Sequeira, Bernardete, and Mendes, Júlio

Abstract

This study explores the sensory experience at heritage sites from the visitors' perspective. A qualitative and exploratory approach was used, considering two data collection methods: semi-structured interviews and in situ focus groups. This empirical study was conducted in the Algarve region, a southern Portugal's sea and sun destination. The data was compiled and analyzed through a thematic content with QSR NVivo 12. The findings suggest that managers should explore and understand tangible, intangible (or immaterial) elements that influence visitors' experiences, attitudes, and behaviours toward the physical environment. In this sense, managers must converge efforts to highlight the sensory cues intrinsic to each site. Furthermore, considering the scarce research addressing sensory experiences in heritage contexts, this study contributes to the literature by exploring the role of the sensory dimension of experiencing a monument that is one of the main attractions in a seasonal mass tourism destination. A framework is presented, which can help managers to design sensory experiences in a built heritage context and assist researchers in future studies. In addition to that, this research also provides some practical implications for management and depicts several leads to future research. [ABSTRACT FROM AUTHOR]

Published
2024
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40. Decrease in APP and CP mRNA expression supports impairment of iron export in Alzheimer's disease patients

Author

Guerreiro, Cláudia, Silva, Bruno, Crespo, Ângela C., Marques, Liliana, Costa, Sónia, Timóteo, Ângela, Marcelino, Erica, Maruta, Carolina, Vilares, Arminda, Matos, Mafalda, Couto, Frederico Simões, Faustino, Paula, Verdelho, Ana, Guerreiro, Manuela, Herrero, Ana, Costa, Cristina, de Mendonça, Alexandre, Martins, Madalena, and Costa, Luciana

Published
2015
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41. Different MMSE domains are associated to cognitive decline and education

Author

Cardoso, Sandra, Barros, Ricardo, Marôco, João, De Mendonça, Alexandre, Guerreiro, Manuela, and Repositório da Universidade de Lisboa

Subjects
Mild Cognitive Impairment, Neuropsychology and Physiological Psychology, mental disorders, Domains, Developmental and Educational Psychology, Mild cognitive impairment, Mini-Mental State Examination, Cognitive decline, Dementia, behavioral disciplines and activities, MMSE, MiniMental state examination, Education
Abstract

© 2022 Taylor & Francis Group, LLC., The Mini-Mental State Examination (MMSE) is a long-established test to screen for dementia, estimate the severity and monitor the progression of cognitive impairment. The MMSE total score is dependent upon demographic factors, particularly education, but little is known about how education influences the 6 distinct MMSE cognitive domains. The present study aims to understand how the performances in the MMSE cognitive domains reflect clinical diagnosis and educational level. The study recruited 1043 participants, comprising 388 healthy controls, 360 patients with Mild Cognitive Impairment (MCI) and 295 patients with dementia. The association of the MMSE cognitive domains scores with clinical diagnosis (healthy, MCI, dementia) and educational level (primary education, middle school, high school and university/college) was analyzed with a multivariate ordinal regression model. The scores in all MMSE domains were generally higher in healthy controls as compared to patients with MCI, and higher in these as compared to patients with dementia. The MMSE domain Constructional ability was associated to the education level, the domains Orientation, Recall and Language were associated to diagnosis, Attention and calculation was associated to both education level and diagnosis, and Registration was not associated to either education or diagnosis. In conclusion, impairment in specific MMSE domains pinpoints cognitive decline, probably indicating brain areas affected by neurodegeneration, and impairment in others reflects lower education levels and the lack of acquisition of relevant schooling abilities.

Published
2022
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43. Class Imbalance in the Prediction of Dementia from Neuropsychological Data

Author

Nunes, Cecília, Silva, Dina, Guerreiro, Manuela, de Mendonça, Alexandre, Carvalho, Alexandra M., Madeira, Sara C., Hutchison, David, editor, Kanade, Takeo, editor, Kittler, Josef, editor, Kleinberg, Jon M., editor, Mattern, Friedemann, editor, Mitchell, John C., editor, Naor, Moni, editor, Nierstrasz, Oscar, editor, Pandu Rangan, C., editor, Steffen, Bernhard, editor, Sudan, Madhu, editor, Terzopoulos, Demetri, editor, Tygar, Doug, editor, Vardi, Moshe Y., editor, Weikum, Gerhard, editor, Goebel, Randy, editor, Siekmann, Jörg, editor, Wahlster, Wolfgang, editor, Correia, Luís, editor, Reis, Luís Paulo, editor, and Cascalho, José, editor

Published
2013
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44. Genetic and biochemical markers in patients with Alzheimer's disease support a concerted systemic iron homeostasis dysregulation

Author

Crespo, Ângela C., Silva, Bruno, Marques, Liliana, Marcelino, Erica, Maruta, Carolina, Costa, Sónia, Timóteo, Ângela, Vilares, Arminda, Couto, Frederico Simões, Faustino, Paula, Correia, Ana Paula, Verdelho, Ana, Porto, Graça, Guerreiro, Manuela, Herrero, Ana, Costa, Cristina, de Mendonça, Alexandre, Costa, Luciana, and Martins, Madalena

Published
2014
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