454 results on '"Günther, Torsten"'
Search Results
2. Bioarchaeological evidence of one of the earliest Islamic burials in the Levant.
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Bolívar, Héctor, Ureña, Irene, Santana, Jonathan, Petersen, Andrew, Iriarte, Eneko, Kırdök, Emrah, Bergfeldt, Nora, Mora, Alice, Jakobsson, Mattias, Abdo, Khaled, Braemer, Frank, Smith, Colin, Ibañez, Juan, Götherström, Anders, Günther, Torsten, Valdiosera, Cristina, and Srigyan, Megha
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Archaeology ,Burial ,Ethnicity ,Genomics ,Humans ,White People - Abstract
The Middle East plays a central role in human history harbouring a vast diversity of ethnic, cultural and religious groups. However, much remains to be understood about past and present genomic diversity in this region. Here we present a multidisciplinary bioarchaeological analysis of two individuals dated to the late 7th and early 8th centuries, the Umayyad Era, from Tell Qarassa, an open-air site in modern-day Syria. Radiocarbon dates and burial type are consistent with one of the earliest Islamic Arab burials in the Levant. Interestingly, we found genomic similarity to a genotyped group of modern-day Bedouins and Saudi rather than to most neighbouring Levantine groups. This study represents the genomic analysis of a secondary use site with characteristics consistent with an early Islamic burial in the Levant. We discuss our findings and possible historic scenarios in the light of forces such as genetic drift and their possible interaction with religious and cultural processes (including diet and subsistence practices).
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- 2022
3. Genetic continuity, isolation, and gene flow in Stone Age Central and Eastern Europe
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Mattila, Tiina M., Svensson, Emma M., Juras, Anna, Günther, Torsten, Kashuba, Natalija, Ala-Hulkko, Terhi, Chyleński, Maciej, McKenna, James, Pospieszny, Łukasz, Constantinescu, Mihai, Rotea, Mihai, Palincaș, Nona, Wilk, Stanisław, Czerniak, Lech, Kruk, Janusz, Łapo, Jerzy, Makarowicz, Przemysław, Potekhina, Inna, Soficaru, Andrei, Szmyt, Marzena, Szostek, Krzysztof, Götherström, Anders, Storå, Jan, Netea, Mihai G., Nikitin, Alexey G., Persson, Per, Malmström, Helena, and Jakobsson, Mattias
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- 2023
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4. Ancient Sheep Genomes reveal four Millennia of North European Short-Tailed Sheep in the Baltic Sea region
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Larsson, Martin N A, primary, Morell Miranda, Pedro, additional, Pan, Li, additional, Başak Vural, Kıvılcım, additional, Kaptan, Damla, additional, Rodrigues Soares, André Elias, additional, Kivikero, Hanna, additional, Kantanen, Juha, additional, Somel, Mehmet, additional, Özer, Füsun, additional, Johansson, Anna M, additional, Storå, Jan, additional, and Günther, Torsten, additional
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- 2024
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5. Resolving the clutter of naming “Eve’s” descendants
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Günther, Torsten, primary
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- 2024
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6. Bioarchaeological evidence of one of the earliest Islamic burials in the Levant
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Srigyan, Megha, Bolívar, Héctor, Ureña, Irene, Santana, Jonathan, Petersen, Andrew, Iriarte, Eneko, Kırdök, Emrah, Bergfeldt, Nora, Mora, Alice, Jakobsson, Mattias, Abdo, Khaled, Braemer, Frank, Smith, Colin, Ibañez, Juan José, Götherström, Anders, Günther, Torsten, and Valdiosera, Cristina
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- 2022
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7. Genomic ancestry and social dynamics of the last hunter-gatherers of Atlantic France
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Simões, Luciana G., Peyroteo Stjerna, Rita, Marchand, Grégor, Bernhardsson, Carolina, Vialet, Amélie, Chetty, Darshan, Alacamli, Erkin, Edlund, Hanna, Bouquin, Denis, Dina, Christian, Garmond, Nicolas, Günther, Torsten, Jakobsson, Mattias, Simões, Luciana G., Peyroteo Stjerna, Rita, Marchand, Grégor, Bernhardsson, Carolina, Vialet, Amélie, Chetty, Darshan, Alacamli, Erkin, Edlund, Hanna, Bouquin, Denis, Dina, Christian, Garmond, Nicolas, Günther, Torsten, and Jakobsson, Mattias
- Abstract
Since the early Holocene, western and central Europe was inhabited by a genetically distinct group of Western Hunter-Gatherers (WHGs). This group was eventually replaced and assimilated by the incoming Neolithic farmers. The western Atlantic façade was home to some of the last Mesolithic sites of mainland Europe, represented by the iconic open-air sites at Hoedic and Téviec in southern Brittany, France. These sites are known for the unusually well-preserved and rich burials. Genomic studies of Mesolithic European hunter-gatherers have been limited to single or a few individuals per site and our understanding of the social dynamics of the last Mesolithic hunter-gatherers of Europe and their interactions with incoming farmers is limited. We sequenced and analyzed the complete genomes of 10 individuals from the Late Mesolithic sites of Hoedic, Téviec, and Champigny, in France, four of which sequenced to between 23- and 8-times genome coverage. The analysis of genomic, chronological and dietary data revealed that the Late Mesolithic populations in Brittany maintained distinct social units within a network of exchanging mates. This resulted in low intra-group biological relatedness that prevented consanguineous mating, despite the small population size of the Late Mesolithic groups. We found no genetic ancestry from Neolithic farmers in the analyzed hunter-gatherers, even though some of them may have coexisted with the first farming groups in neighboring regions. Hence, contrary to previous conclusions based on stable isotope data from the same sites, the Late Mesolithic forager community was limited in mate-exchange to neighboring hunter-gatherer groups, to the exclusion of Neolithic farmers., Authors in the list of papers of Lucianan G. Simões thesis: Luciana G. Simões, Rita Peyroteo-Stjerna, Carolina Bernhardsson, Torsten Günther, Grégor Marchand, Hanna Edlund, Darshan Chetty, Denis Bouquin, Nicolas Garmond, Amélie Vialet, Mattias Jakobsson
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- 2024
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8. Population Genomic History of the Endangered Anatolian and Cyprian Mouflons in Relation to Worldwide Wild, Feral, and Domestic Sheep Lineages
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Atag, Gözde, Kaptan, Damla, Yüncü, Eren, Vural, Kivilcim Basak, Mereu, Paolo, Pirastru, Monica, Barbato, Mario, Leoni, Giovanni Giuseppe, Güler, Merve Nur, Er, Tugce, Eker, Elifnaz, Yazici, Tunca Deniz, Kilic, Muhammed Siddik, Altinisik, Nefize Ezgi, Celik, Ecem Ayse, Morell Miranda, Pedro, Dehasque, Marianne, Floridia, Viviana, Götherström, Anders, Bilgin, Cemal Can, Togan, Inci, Günther, Torsten, Özer, Füsun, Hadjisterkotis, Eleftherios, Somel, Mehmet, Atag, Gözde, Kaptan, Damla, Yüncü, Eren, Vural, Kivilcim Basak, Mereu, Paolo, Pirastru, Monica, Barbato, Mario, Leoni, Giovanni Giuseppe, Güler, Merve Nur, Er, Tugce, Eker, Elifnaz, Yazici, Tunca Deniz, Kilic, Muhammed Siddik, Altinisik, Nefize Ezgi, Celik, Ecem Ayse, Morell Miranda, Pedro, Dehasque, Marianne, Floridia, Viviana, Götherström, Anders, Bilgin, Cemal Can, Togan, Inci, Günther, Torsten, Özer, Füsun, Hadjisterkotis, Eleftherios, and Somel, Mehmet
- Abstract
Once widespread in their homelands, the Anatolian mouflon (Ovis gmelini anatolica) and the Cyprian mouflon (Ovis gmelini ophion) were driven to near extinction during the 20th century and are currently listed as endangered populations by the International Union for Conservation of Nature. While the exact origins of these lineages remain unclear, they have been suggested to be close relatives of domestic sheep or remnants of proto-domestic sheep. Here, we study whole genome sequences of n = 5 Anatolian mouflons and n = 10 Cyprian mouflons in terms of population history and diversity, comparing them with eight other extant sheep lineages. We find reciprocal genetic affinity between Anatolian and Cyprian mouflons and domestic sheep, higher than all other studied wild sheep genomes, including the Iranian mouflon (O. gmelini). Studying diversity indices, we detect a considerable load of short runs of homozygosity blocks (<2 Mb) in both Anatolian and Cyprian mouflons, reflecting small effective population size (N-e). Meanwhile, N-e and mutation load estimates are lower in Cyprian compared with Anatolian mouflons, suggesting the purging of recessive deleterious variants in Cyprian sheep under a small long-term N-e, possibly attributable to founder effects, island isolation, introgression from domestic lineages, or differences in their bottleneck dynamics. Expanding our analyses to worldwide wild and feral Ovis genomes, we observe varying viability metrics among different lineages and a limited consistency between viability metrics and International Union for Conservation of Nature conservation status. Factors such as recent inbreeding, introgression, and unique population dynamics may have contributed to the observed disparities.
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- 2024
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9. READv2: Advanced and user-friendly detection of biological relatedness in archaeogenomics
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Alaçamlı, Erkin, primary, Naidoo, Thijessen, additional, Aktürk, Şevval, additional, Güler, Merve N, additional, Mapelli, Igor, additional, Vural, Kıvılcım Başak, additional, Somel, Mehmet, additional, Malmström, Helena, additional, and Günther, Torsten, additional
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- 2024
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10. The Genomic Legacy of Human Management and sex-biased Aurochs hybridization in Iberian Cattle
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Günther, Torsten, primary, Chisausky, Jacob, additional, Galindo-Pellicena, M. Ángeles, additional, Iriarte, Eneko, additional, Gardyn, Oscar Cortes, additional, Eusebi, Paulina G., additional, García-González, Rebeca, additional, Urena, Irene, additional, Moreno, Marta, additional, Alday, Alfonso, additional, Rojo, Manuel, additional, Pérez, Amalia, additional, Rodríguez, Cristina Tejedor, additional, de Lagrán, Iñigo García Martínez, additional, Arsuaga, Juan Luis, additional, Carretero, José-Miguel, additional, Götherström, Anders, additional, Smith, Colin, additional, and Valdiosera, Cristina, additional
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- 2024
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11. New Organizing: Wie Großorganisationen Agilität, Holacracy & Co. einführen – und was man daraus lernen kann
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Torsten Groth, Gerhard P. Krejci, Stefan Günther, Torsten Groth, Gerhard P. Krejci, Stefan Günther and Torsten Groth, Gerhard P. Krejci, Stefan Günther, Torsten Groth, Gerhard P. Krejci, Stefan Günther
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- 2021
12. Population genomic history of the endangered Anatolian and Cyprian mouflons in relation to worldwide wild, feral and domestic sheep lineages
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Atağ, Gözde, primary, Kaptan, Damla, additional, Yüncü, Eren, additional, Vural, Kıvılcım B., additional, Mereu, Paolo, additional, Pirastru, Monica, additional, Barbato, Mario, additional, Leoni, Giovanni G., additional, Güler, Merve N., additional, Er, Tuğçe, additional, Eker, Elifnaz, additional, Yazıcı, Tunca Deniz, additional, Kılıç, Muhammed Sıddık, additional, Altınışık, N. Ezgi, additional, Çelik, Ecem Ayşe, additional, Miranda, Pedro Morell, additional, Dehasque, Marianne, additional, Floridia, Viviana, additional, Götherström, Anders, additional, Bilgin, C.Can, additional, Togan, İnci, additional, Günther, Torsten, additional, Özer, Füsun, additional, Hadjisterkotis, Eleftherios, additional, and Somel, Mehmet, additional
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- 2023
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13. Archaeogenetic analysis of Neolithic sheep from Anatolia suggests a complex demographic history since domestication
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Yurtman, Erinç, Özer, Onur, Yüncü, Eren, Dağtaş, Nihan Dilşad, Koptekin, Dilek, Çakan, Yasin Gökhan, Özkan, Mustafa, Akbaba, Ali, Kaptan, Damla, Atağ, Gözde, Vural, Kıvılcım Başak, Gündem, Can Yümni, Martin, Louise, Kılınç, Gülşah Merve, Ghalichi, Ayshin, Açan, Sinan Can, Yaka, Reyhan, Sağlıcan, Ekin, Lagerholm, Vendela Kempe, Krzewińska, Maja, Günther, Torsten, Morell Miranda, Pedro, Pişkin, Evangelia, Şevketoğlu, Müge, Bilgin, C. Can, Atakuman, Çiğdem, Erdal, Yılmaz Selim, Sürer, Elif, Altınışık, N. Ezgi, Lenstra, Johannes A., Yorulmaz, Sevgi, Abazari, Mohammad Foad, Hoseinzadeh, Javad, Baird, Douglas, Bıçakçı, Erhan, Çevik, Özlem, Gerritsen, Fokke, Özbal, Rana, Götherström, Anders, Somel, Mehmet, Togan, İnci, and Özer, Füsun
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- 2021
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14. Mobility patterns in inland southwestern Sweden during the Neolithic and Early Bronze Age
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Blank, Malou, Sjögren, Karl-Göran, Knipper, Corina, Frei, Karin M, Malmström, Helena, Fraser, Magdalena, Svensson, Emma M., Günther, Torsten, Yngve, Hannes, Jakobsson, Mattias, Götherström, Anders, and Storå, Jan
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- 2021
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15. Demographic reconstruction of the Western sheep expansion from whole-genome sequences
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Morell Miranda, Pedro, primary, Soares, André E R, additional, and Günther, Torsten, additional
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- 2023
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16. The Genomic Legacy of Human Management and sex-biased Aurochs hybridization in Iberian Cattle
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Günther, Torsten, primary, Chisausky, Jacob, additional, Galindo-Pellicena, M. Ángeles, additional, Iriarte, Eneko, additional, Cortes Gardyn, Oscar, additional, Eusebi, Paulina G., additional, García-González, Rebeca, additional, Urena, Irene, additional, Moreno, Marta, additional, Alday, Alfonso, additional, Rojo, Manuel, additional, Pérez, Amalia, additional, Tejedor Rodríguez, Cristina, additional, García Martínez de Lagrán, Iñigo, additional, Arsuaga, Juan Luis, additional, Carretero, José-Miguel, additional, Götherström, Anders, additional, Smith, Colin, additional, and Valdiosera, Cristina, additional
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- 2023
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17. Robust identification of local adaptation from allele frequencies.
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Günther, Torsten and Coop, Graham
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adaptation ,correlation ,differentiation ,environment ,pool-seq ,Adaptation ,Physiological ,Animals ,Environment ,Evolution ,Molecular ,Gene Frequency ,Humans ,Models ,Genetic ,Polymorphism ,Single Nucleotide ,Population ,Software - Abstract
Comparing allele frequencies among populations that differ in environment has long been a tool for detecting loci involved in local adaptation. However, such analyses are complicated by an imperfect knowledge of population allele frequencies and neutral correlations of allele frequencies among populations due to shared population history and gene flow. Here we develop a set of methods to robustly test for unusual allele frequency patterns and correlations between environmental variables and allele frequencies while accounting for these complications based on a Bayesian model previously implemented in the software Bayenv. Using this model, we calculate a set of standardized allele frequencies that allows investigators to apply tests of their choice to multiple populations while accounting for sampling and covariance due to population history. We illustrate this first by showing that these standardized frequencies can be used to detect nonparametric correlations with environmental variables; these correlations are also less prone to spurious results due to outlier populations. We then demonstrate how these standardized allele frequencies can be used to construct a test to detect SNPs that deviate strongly from neutral population structure. This test is conceptually related to FST and is shown to be more powerful, as we account for population history. We also extend the model to next-generation sequencing of population pools-a cost-efficient way to estimate population allele frequencies, but one that introduces an additional level of sampling noise. The utility of these methods is demonstrated in simulations and by reanalyzing human SNP data from the Human Genome Diversity Panel populations and pooled next-generation sequencing data from Atlantic herring. An implementation of our method is available from http://gcbias.org.
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- 2013
18. Ancient Sheep Genomes reveal four Millennia of North European Short-Tailed Sheep in the Baltic Sea region
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Larsson, Martin NA, primary, Miranda, Pedro Morell, additional, Pan, Li, additional, Başak Vural, Kıvılcım, additional, Kaptan, Damla, additional, Rodrigues Soares, André Elias, additional, Kivikero, Hanna, additional, Kantanen, Juha, additional, Somel, Mehmet, additional, Özer, Füsun, additional, Johansson, Anna M, additional, Storå, Jan, additional, and Günther, Torsten, additional
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- 2023
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19. Demographic Reconstruction of the Western Sheep Expansion from Whole-Genome sequences
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Miranda, Pedro Morell, primary, Soares, André ER, additional, and Günther, Torsten, additional
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- 2023
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20. Northwest African Neolithic initiated by migrants from Iberia and Levant
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Simões, Luciana G., primary, Günther, Torsten, additional, Martínez-Sánchez, Rafael M., additional, Vera-Rodríguez, Juan Carlos, additional, Iriarte, Eneko, additional, Rodríguez-Varela, Ricardo, additional, Bokbot, Youssef, additional, Valdiosera, Cristina, additional, and Jakobsson, Mattias, additional
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- 2023
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21. Imputed genomes and haplotype-based analyses of the Picts of early medieval Scotland reveal fine-scale relatedness between Iron Age, early medieval and the modern people of the UK
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Morez, Adeline, primary, Britton, Kate, additional, Noble, Gordon, additional, Günther, Torsten, additional, Götherström, Anders, additional, Rodríguez-Varela, Ricardo, additional, Kashuba, Natalija, additional, Martiniano, Rui, additional, Talamo, Sahra, additional, Evans, Nicholas J., additional, Irish, Joel D., additional, Donald, Christina, additional, and Girdland-Flink, Linus, additional
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- 2023
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22. Imputed genomes and haplotype-based analyses of the Picts of early medieval Scotland reveal fine-scale relatedness between Iron Age, early medieval and the modern people of the UK
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Morez, Adeline, Britton, Kate, Noble, Gordon, Günther, Torsten, Gotherstrom, Anders D., Rodriguez-Varela, Ricardo, Kashuba, Natalija, Martiniano, Rui, Talamo, Sahra, Evans, Nicholas, Irish, Joel, Donald, Christina, Girdland-Flink, Linus, Morez, Adeline, Britton, Kate, Noble, Gordon, Günther, Torsten, Gotherstrom, Anders D., Rodriguez-Varela, Ricardo, Kashuba, Natalija, Martiniano, Rui, Talamo, Sahra, Evans, Nicholas, Irish, Joel, Donald, Christina, and Girdland-Flink, Linus
- Abstract
There are longstanding questions about the origins and ancestry of the Picts of early medieval Scotland (ca. 300-900 CE), prompted in part by exotic medieval origin myths, their enigmatic symbols and inscriptions, and the meagre textual evidence. The Picts, first mentioned in the late 3(rd) century CE resisted the Romans and went on to form a powerful kingdom that ruled over a large territory in northern Britain. In the 9(th) and 10(th) centuries Gaelic language, culture and identity became dominant, transforming the Pictish realm into Alba, the precursor to the medieval kingdom of Scotland. To date, no comprehensive analysis of Pictish genomes has been published, and questions about their biological relationships to other cultural groups living in Britain remain unanswered. Here we present two high-quality Pictish genomes (2.4 and 16.5X coverage) from central and northern Scotland dated from the 5(th)-7(th) century which we impute and co-analyse with >8,300 previously published ancient and modern genomes. Using allele frequency and haplotype-based approaches, we can firmly place the genomes within the Iron Age gene pool in Britain and demonstrate regional biological affinity. We also demonstrate the presence of population structure within Pictish groups, with Orcadian Picts being genetically distinct from their mainland contemporaries. When investigating Identity-By-Descent (IBD) with present-day genomes, we observe broad affinities between the mainland Pictish genomes and the present-day people living in western Scotland, Wales, Northern Ireland and Northumbria, but less with the rest of England, the Orkney islands and eastern Scotland-where the political centres of Pictland were located. The pre-Viking Age Orcadian Picts evidence a high degree of IBD sharing across modern Scotland, Wales, Northern Ireland, and the Orkney islands, demonstrating substantial genetic continuity in Orkney for the last similar to 2,000 years. Analysis of mitochondrial DNA diversity
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- 2023
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23. Northwest African Neolithic initiated by migrants from Iberia and Levant
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Simões, Luciana G., Günther, Torsten, Martinez-Sanchez, Rafael M., Vera-Rodriguez, Juan Carlos, Iriarte, Eneko, Rodriguez-Varela, Ricardo, Bokbot, Youssef, Valdiosera, Cristina, Jakobsson, Mattias, Simões, Luciana G., Günther, Torsten, Martinez-Sanchez, Rafael M., Vera-Rodriguez, Juan Carlos, Iriarte, Eneko, Rodriguez-Varela, Ricardo, Bokbot, Youssef, Valdiosera, Cristina, and Jakobsson, Mattias
- Abstract
In northwestern Africa, lifestyle transitioned from foraging to food production around 7,400 years ago but what sparked that change remains unclear. Archaeological data support conflicting views: (1) that migrant European Neolithic farmers brought the new way of life to North Africa(1-3) or (2) that local hunter-gatherers adopted technological innovations(4,5). The latter view is also supported by archaeogenetic data(6). Here we fill key chronological and archaeogenetic gaps for the Maghreb, from Epipalaeolithic to Middle Neolithic, by sequencing the genomes of nine individuals (to between 45.8- and 0.2-fold genome coverage). Notably, we trace 8,000 years of population continuity and isolation from the Upper Palaeolithic, via the Epipaleolithic, to some Maghrebi Neolithic farming groups. However, remains from the earliest Neolithic contexts showed mostly European Neolithic ancestry. We suggest that farming was introduced by European migrants and was then rapidly adopted by local groups. During the Middle Neolithic a new ancestry from the Levant appears in the Maghreb, coinciding with the arrival of pastoralism in the region, and all three ancestries blend together during the Late Neolithic. Our results show ancestry shifts in the Neolithization of northwestern Africa that probably mirrored a heterogeneous economic and cultural landscape, in a more multifaceted process than observed in other regions.
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- 2023
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24. Demographic reconstruction of the Western sheep expansion from whole-genome sequences
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Morell Miranda, Pedro, Soares, André E. R., Günther, Torsten, Morell Miranda, Pedro, Soares, André E. R., and Günther, Torsten
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As one of the earliest livestock, sheep (Ovis aries) were domesticated in the Fertile Crescent about 12,000–10,000 years ago and have a nearly worldwide distribution today. Most of our knowledge about the timing of their expansions stems from archaeological data but it is unclear how the genetic diversity of modern sheep fits with these dates. We used whole-genome sequencing data of 63 domestic breeds and their wild relatives, the Asiatic mouflon (O. gmelini, previously known as O. orientalis), to explore the demographic history of sheep. On the global scale, our analysis revealed geographic structuring among breeds with unidirectional recent gene flow from domestics into Asiatic mouflons. We then selected 4 representative breeds from Spain, Morocco, the United Kingdom, and Iran to build a comprehensive demographic model of the Western sheep expansion. We inferred a single domestication event around 11,000 years ago. The subsequent westward expansion is dated to approximately 7,000 years ago, later than the original Neolithic expansion of sheep and slightly predating the Secondary Product Revolution associated with wooly sheep. We see some signals of recent gene flow from an ancestral population into Southern European breeds which could reflect admixture with feral European mouflon. Furthermore, our results indicate that many breeds experienced a reduction of their effective population size during the last centuries, probably associated with modern breed development. Our study provides insights into the complex demographic history of Western Eurasian sheep, highlighting interactions between breeds and their wild counterparts.
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- 2023
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25. Genetic continuity, isolation, and gene flow in Stone Age Central and Eastern Europe
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Mattila, Tiina, Svensson, Emma, Juras, Anna, Günther, Torsten, Kashuba, Natalija, Ala-Hulkko, Terhi, Chyleński, Maciej, Mckenna, James, Pospieszny, Łukasz, Constantinescu, Mihai, Rotea, Mihai, Palincaș, Nona, Wilk, Stanisław, Czerniak, Lech, Kruk, Janusz, Łapo, Jerzy, Makarowicz, Przemysław, Potekhina, Inna, Soficaru, Andrei, Szmyt, Marzena, Szostek, Krzysztof, Götherström, Anders, Storå, Jan, Netea, Mihai, Nikitin, Alexey, Persson, Per, Malmström, Helena, Jakobsson, Mattias, Mattila, Tiina, Svensson, Emma, Juras, Anna, Günther, Torsten, Kashuba, Natalija, Ala-Hulkko, Terhi, Chyleński, Maciej, Mckenna, James, Pospieszny, Łukasz, Constantinescu, Mihai, Rotea, Mihai, Palincaș, Nona, Wilk, Stanisław, Czerniak, Lech, Kruk, Janusz, Łapo, Jerzy, Makarowicz, Przemysław, Potekhina, Inna, Soficaru, Andrei, Szmyt, Marzena, Szostek, Krzysztof, Götherström, Anders, Storå, Jan, Netea, Mihai, Nikitin, Alexey, Persson, Per, Malmström, Helena, and Jakobsson, Mattias
- Abstract
The genomic landscape of Stone Age Europe was shaped by multiple migratory waves and population replacements, but different regions do not all show similar patterns. To refine our understanding of the population dynamics before and after the dawn of the Neolithic, we generated and analyzed genomic sequence data from human remains of 56 individuals from the Mesolithic, Neolithic, and Eneolithic across Central and Eastern Europe. We found that Mesolithic European populations formed a geographically widespread isolation-by-distance zone ranging from Central Europe to Siberia, which was already established 10,000 years ago. We found contrasting patterns of population continuity during the Neolithic transition: people around the lower Dnipro Valley region, Ukraine, showed continuity over 4000 years, from the Mesolithic to the end of the Neolithic, in contrast to almost all other parts of Europe where population turnover drove this cultural change, including vast areas of Central Europe and around the Danube River.
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- 2023
26. Robust genome-wide ancestry inference for heterogeneous datasets: illustrated using the 1,000 genome project with 3D facial images
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Li, Jiarui, Zarzar, Tomás González, White, Julie D., Indencleef, Karlijne, Hoskens, Hanne, Matthews, Harry, Nauwelaers, Nele, Zaidi, Arslan, Eller, Ryan J., Herrick, Noah, Günther, Torsten, Svensson, Emma M., Jakobsson, Mattias, Walsh, Susan, Van Steen, Kristel, Shriver, Mark D., and Claes, Peter
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- 2020
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27. Copy number determination of the gene for the human pancreatic polypeptide receptor NPY4R using read depth analysis and droplet digital PCR
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Shebanits, Kateryna, Günther, Torsten, Johansson, Anna C. V., Maqbool, Khurram, Feuk, Lars, Jakobsson, Mattias, and Larhammar, Dan
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- 2019
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28. The population genomic legacy of the second plague pandemic
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Gopalakrishnan, Shyam, primary, Ebenesersdóttir, S. Sunna, additional, Lundstrøm, Inge K.C., additional, Turner-Walker, Gordon, additional, Moore, Kristjan H.S., additional, Luisi, Pierre, additional, Margaryan, Ashot, additional, Martin, Michael D., additional, Ellegaard, Martin Rene, additional, Magnússon, Ólafur þ., additional, Sigurðsson, Ásgeir, additional, Snorradóttir, Steinunn, additional, Magnúsdóttir, Droplaug N., additional, Laffoon, Jason E., additional, van Dorp, Lucy, additional, Liu, Xiaodong, additional, Moltke, Ida, additional, Ávila-Arcos, María C., additional, Schraiber, Joshua G., additional, Rasmussen, Simon, additional, Juan, David, additional, Gelabert, Pere, additional, de-Dios, Toni, additional, Fotakis, Anna K., additional, Iraeta-Orbegozo, Miren, additional, Vågene, Åshild J., additional, Denham, Sean Dexter, additional, Christophersen, Axel, additional, Stenøien, Hans K., additional, Vieira, Filipe G., additional, Liu, Shanlin, additional, Günther, Torsten, additional, Kivisild, Toomas, additional, Moseng, Ole Georg, additional, Skar, Birgitte, additional, Cheung, Christina, additional, Sandoval-Velasco, Marcela, additional, Wales, Nathan, additional, Schroeder, Hannes, additional, Campos, Paula F., additional, Guðmundsdóttir, Valdís B., additional, Sicheritz-Ponten, Thomas, additional, Petersen, Bent, additional, Halgunset, Jostein, additional, Gilbert, Edmund, additional, Cavalleri, Gianpiero L., additional, Hovig, Eivind, additional, Kockum, Ingrid, additional, Olsson, Tomas, additional, Alfredsson, Lars, additional, Hansen, Thomas F., additional, Werge, Thomas, additional, Willerslev, Eske, additional, Balloux, Francois, additional, Marques-Bonet, Tomas, additional, Lalueza-Fox, Carles, additional, Nielsen, Rasmus, additional, Stefánsson, Kári, additional, Helgason, Agnar, additional, and Gilbert, M. Thomas P., additional
- Published
- 2022
- Full Text
- View/download PDF
29. Genetic continuity, isolation, and gene flow in Stone Age Central and Eastern Europe
- Author
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Mattila, Tiina, Svensson, Emma, Juras, Anna, Günther Torsten an, Torsten, Kashuba, Natalija, Ala-Hulkko, The erhi, Chyleński, Maciej, Pospieszny, Łukasz, Constantinescu, Mihai, Rotea, Mihai, Palincaș, Nona, Wilk, Stanisław, Czerniak, Lech, Kruk, Janusz, Łapo, Jerzy, Makarowicz, Przemysław, Potiekhina, Inna, Soficaruc, Andrei, Szmyt, Marzena, Szostek, Krzysztof, Götherström, Anders, Storå, Jan, Netea, Mihai, Nikitin, Alexey, Persson, Per, Malmström, Helena, and Jakobsson, Mattias
- Subjects
300 Social sciences, sociology & anthropology ,610 Medicine & health - Abstract
The genomic landscape of Stone Age Europe was shaped by multiple migratory waves and population replacements, but different regions do not all show the same patterns. To refine our understanding of the population dynamics before and after the dawn of the Neolithic, we generated and analyzed genomic sequence data from human remains of 56 individuals from the Mesolithic, Neolithic and Eneolithic across Central and Eastern Europe. We found that Mesolithic European populations formed a geographically widespread isolation-by-distance zone ranging from Central Europe to Siberia, which was already established 10 000 years ago. We also found contrasting patterns of population continuity during the Neolithic transition: people around the lower Dnipro Valley region, Ukraine, showed continuity over 4 000 years, from the Mesolithic to the end of Neolithic, in contrast to almost all other parts of Europe where population turnover drove this cultural change, including vast areas of Central Europe and around the Danube River.
- Published
- 2022
30. Genetic continuity, isolation, and gene flow in Stone Age Central and Eastern Europe
- Author
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Mattila, Tiina, primary, Svensson, Emma, additional, Juras, Anna, additional, Günther, Torsten, additional, Kashuba, Natalija, additional, Ala-Hulkko, Terhi, additional, Chyleński, Maciej, additional, Pospieszny, Łukasz, additional, Constantinescu, Mihai, additional, Rotea, Mihai, additional, Palincaș, Nona, additional, Wilk, Stanisław, additional, Czerniak, Lech, additional, Kruk, Janusz, additional, Łapo, Jerzy, additional, Makarowicz, Przemysław, additional, Potekhina, Inna, additional, Soficaruc, Andrei, additional, Szmyt, Marzena, additional, Szostek, Krzysztof, additional, Götherström, Anders, additional, Storå, Jan, additional, Netea, Mihai, additional, Nikitin, Alexey, additional, Persson, Per, additional, Malmström, Helena, additional, and Jakobsson, Mattias, additional
- Published
- 2022
- Full Text
- View/download PDF
31. Decision letter: A novel lineage of the Capra genus discovered in the Taurus Mountains of Turkey using ancient genomics
- Author
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Günther, Torsten, additional and Miranda, Pedro Morell, additional
- Published
- 2022
- Full Text
- View/download PDF
32. Imputed genomes and haplotype-based analyses of the Picts of early medieval Scotland reveal fine-scale relatedness between Iron Age, early medieval and the modern people of the UK
- Author
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Morez, Adeline, primary, Britton, Kate, additional, Noble, Gordon, additional, Günther, Torsten, additional, Götherström, Anders, additional, Rodríguez-Varela, Ricardo, additional, Kashuba, Natalija, additional, Martiniano, Rui, additional, Talamo, Sahra, additional, Evans, Nicholas J., additional, Irish, Joel D., additional, Donald, Christina, additional, and Girdland-Flink, Linus, additional
- Published
- 2022
- Full Text
- View/download PDF
33. Southern African ancient genomes estimate modern human divergence to 350,000 to 260,000 years ago
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Schlebusch, Carina M., Malmström, Helena, Günther, Torsten, Sjödin, Per, Coutinho, Alexandra, Edlund, Hanna, Munters, Arielle R., Vicente, Mário, Steyn, Maryna, Soodyall, Himla, Lombard, Marlize, and Jakobsson, Mattias
- Published
- 2017
- Full Text
- View/download PDF
34. Ancient DNA from a 2700-year-old goitered gazelle (Gazella subgutturosa) supports gazelle hunting in Iron Age Central Asia
- Author
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Rodrigues Soares, André Elias, Boroffka, Nikolaus, Schröder, Oskar, Sverchkov, Leonid, Benecke, Norbert, Günther, Torsten, Rodrigues Soares, André Elias, Boroffka, Nikolaus, Schröder, Oskar, Sverchkov, Leonid, Benecke, Norbert, and Günther, Torsten
- Abstract
Central Asia has been an important region connecting the different parts of Eurasia throughout history and prehistory, with large states developing in this region during the Iron Age. Archaeogenomics is a powerful addition to the zooarchaeological toolkit for understanding the relation of these societies to animals. Here, we present the genetic identification of a goitered gazelle specimen (Gazella subgutturosa) at the site Gazimulla-Tepa, in modern-day Uzbekistan, supporting hunting of the species in the region during the Iron Age. The sample was directly radiocarbon dated to 2724-2439 calBP. A phylogenetic analysis of the mitochondrial genome places the individual into the modern variation of G. subgutturosa. Our data do represent both the first ancient DNA and the first nuclear DNA sequences of this species. The lack of genomic resources available for this gazelle and related species prevented us from performing a more in-depth analysis of the nuclear sequences generated. Therefore, we are making our sequence data available to the research community to facilitate other research of this nowadays threatened species which has been subject to human hunting for several millennia across its entire range on the Asian continent.
- Published
- 2022
- Full Text
- View/download PDF
35. Multidisciplinary investigation reveals an individual of West African origin buried in a Portuguese Mesolithic shell midden four centuries ago
- Author
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Peyroteo Stjerna, Rita, Simões, Luciana G., Fernandes, Ricardo, Lopes, Gonçalo, Günther, Torsten, Jakobsson, Mattias, Peyroteo Stjerna, Rita, Simões, Luciana G., Fernandes, Ricardo, Lopes, Gonçalo, Günther, Torsten, and Jakobsson, Mattias
- Abstract
Cabeço da Amoreira is a well-studied shell midden with a robust chronology based on a large number ofradiocarbon dates on Mesolithic human burials. Surprisingly, we discovered one individual that lived about 400years ago buried in this site. We employed a multidisciplinary approach integrating archaeology, historical records,genetics, radiocarbon dating and stable isotope analysis to investigate the biogeographic origins of thisindividual and burial circumstances. We could determine that this was a man of West African origin, probablyfrom Senegambia, arriving in Portugal via the Trans-Atlantic Slave Trade. Our study provides new insights intoaspects of the life and death of a first-generation African individual in Portugal during the Trans-Atlantic SlaveTrade period and highlights the power of multidisciplinary research to unravel unwritten history.
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- 2022
- Full Text
- View/download PDF
36. Genetic continuity, isolation, and gene flow in Stone Age Central and Eastern Europe
- Author
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Tiina Mattila, Svensson, Emma, Juras, Anna, Günther, Torsten, Kashuba, Natalija, Ala-Hulkko, Terhi, Chyleński, Maciej, Pospieszny, Łukasz, Constantinescu, Mihai, Rotea, Mihai, Palincaș, Nona, Wilk, Stanisław, Lech Czerniak, Kruk, Janusz, Łapo, Jerzy, Makarowicz, Przemysław, Potekhina, Inna, Soficaruc, Andrei, Szmyt, Marzena, Szostek, Krzysztof, Götherström, Anders, Storå, Jan, Netea, Mihai, Nikitin, Alexey, Persson, Per, Malmström, Helena, Jakobsson, Mattias, Tiina Mattila, Svensson, Emma, Juras, Anna, Günther, Torsten, Kashuba, Natalija, Ala-Hulkko, Terhi, Chyleński, Maciej, Pospieszny, Łukasz, Constantinescu, Mihai, Rotea, Mihai, Palincaș, Nona, Wilk, Stanisław, Lech Czerniak, Kruk, Janusz, Łapo, Jerzy, Makarowicz, Przemysław, Potekhina, Inna, Soficaruc, Andrei, Szmyt, Marzena, Szostek, Krzysztof, Götherström, Anders, Storå, Jan, Netea, Mihai, Nikitin, Alexey, Persson, Per, Malmström, Helena, and Jakobsson, Mattias
- Abstract
The genomic landscape of Stone Age Europe was shaped by multiple migratory waves and population replacements, but different regions do not all show the same patterns. To refine our understanding of the population dynamics before and after the dawn of the Neolithic, we generated and analyzed genomic sequence data from human remains of 56 individuals from the Mesolithic, Neolithic and Eneolithic across Central and Eastern Europe. We found that Mesolithic European populations formed a geographically widespread isolation-by-distance zone ranging from Central Europe to Siberia, which was already established 10,000 years ago. We also found contrasting patterns of population continuity during the Neolithic transition: people around the lower Dnipro Valley region, Ukraine, showed continuity over 4,000 years, from the Mesolithic to the end of Neolithic, in contrast to almost all other parts of Europe where population turnover drove this cultural change, including vast areas of Central Europe and around the Danube River.
- Published
- 2022
37. The population genomic legacy of the second plague pandemic
- Author
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Gopalakrishnan, Shyam, Ebenesersdottir, S. Sunna, Lundström, Inge K. C., Turner-Walker, Gordon, Moore, Kristjan H. S., Luisi, Pierre, Margaryan, Ashot, Martin, Michael D., Ellegaard, Martin Rene, Magnusson, Olafur P., Sigurosson, Asgeir, Snorradottir, Steinunn, Magnusdottir, Droplaug N., Laffoon, Jason E., van Dorp, Lucy, Liu, Xiaodong, Moltke, Ida, Avila-Arcos, Maria C., Schraiber, Joshua G., Rasmussen, Simon, Juan, David, Gelabert, Pere, de-Dios, Toni, Fotakis, Anna K., Iraeta-Orbegozo, Miren, Vågene, Åshild J., Denham, Sean Dexter, Christophersen, Axel, Stenøien, Hans K., Vieira, Filipe G., Liu, Shanlin, Günther, Torsten, Kivisild, Toomas, Moseng, Ole Georg, Skar, Birgitte, Cheung, Christina, Sandoval-Velasco, Marcela, Wales, Nathan, Schroeder, Hannes, Campos, Paula F., Guomundsdottir, Valdis B., Sicheritz-Ponten, Thomas, Peterson, Bent, Halgunset, Jostein, Gilbert, Edmund, Cavalleri, Gianpiero L., Hovig, Eivind, Kockum, Ingrid, Olsson, Tomas, Alfredsson, Lars, Hansen, Thomas F., Werge, Thomas, Willerslev, Eske, Balloux, Francois, Marques-Bonet, Tomas, Lalueza-Fox, Carles, Nielsen, Rasmus, Stefansson, Kari, Holgason, Agnar, Gilbert, M. Thomas P., Gopalakrishnan, Shyam, Ebenesersdottir, S. Sunna, Lundström, Inge K. C., Turner-Walker, Gordon, Moore, Kristjan H. S., Luisi, Pierre, Margaryan, Ashot, Martin, Michael D., Ellegaard, Martin Rene, Magnusson, Olafur P., Sigurosson, Asgeir, Snorradottir, Steinunn, Magnusdottir, Droplaug N., Laffoon, Jason E., van Dorp, Lucy, Liu, Xiaodong, Moltke, Ida, Avila-Arcos, Maria C., Schraiber, Joshua G., Rasmussen, Simon, Juan, David, Gelabert, Pere, de-Dios, Toni, Fotakis, Anna K., Iraeta-Orbegozo, Miren, Vågene, Åshild J., Denham, Sean Dexter, Christophersen, Axel, Stenøien, Hans K., Vieira, Filipe G., Liu, Shanlin, Günther, Torsten, Kivisild, Toomas, Moseng, Ole Georg, Skar, Birgitte, Cheung, Christina, Sandoval-Velasco, Marcela, Wales, Nathan, Schroeder, Hannes, Campos, Paula F., Guomundsdottir, Valdis B., Sicheritz-Ponten, Thomas, Peterson, Bent, Halgunset, Jostein, Gilbert, Edmund, Cavalleri, Gianpiero L., Hovig, Eivind, Kockum, Ingrid, Olsson, Tomas, Alfredsson, Lars, Hansen, Thomas F., Werge, Thomas, Willerslev, Eske, Balloux, Francois, Marques-Bonet, Tomas, Lalueza-Fox, Carles, Nielsen, Rasmus, Stefansson, Kari, Holgason, Agnar, and Gilbert, M. Thomas P.
- Abstract
Human populations have been shaped by catastrophes that may have left long-lasting signatures in their genomes. One notable example is the second plague pandemic that entered Europe in ca. 1,347 CE and repeatedly returned for over 300 years, with typical village and town mortality estimated at 10%–40%.1 It is assumed that this high mortality affected the gene pools of these populations. First, local population crashes reduced genetic diversity. Second, a change in frequency is expected for sequence variants that may have affected survival or susceptibility to the etiologic agent (Yersinia pestis).2 Third, mass mortality might alter the local gene pools through its impact on subsequent migration patterns. We explored these factors using the Norwegian city of Trondheim as a model, by sequencing 54 genomes spanning three time periods: (1) prior to the plague striking Trondheim in 1,349 CE, (2) the 17th–19th century, and (3) the present. We find that the pandemic period shaped the gene pool by reducing long distance immigration, in particular from the British Isles, and inducing a bottleneck that reduced genetic diversity. Although we also observe an excess of large FST values at multiple loci in the genome, these are shaped by reference biases introduced by mapping our relatively low genome coverage degraded DNA to the reference genome. This implies that attempts to detect selection using ancient DNA (aDNA) datasets that vary by read length and depth of sequencing coverage may be particularly challenging until methods have been developed to account for the impact of differential reference bias on test statistics.
- Published
- 2022
- Full Text
- View/download PDF
38. The population genomic legacy of the second plague pandemic
- Author
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Carlsberg Foundation, Danish National Research Foundation, Lundbeck Foundation, European Research Council, Research Council of Norway, Science Foundation Ireland, Gopalakrishnan, Shyam, Ebenesersdóttir, Sigríður Sunna, Lundstrøm, Inge K.C., Turner-Walker, Gordon, Moore, Kristjan H.S., Luisi, Pierre, Margaryan, Ashot, Martin, Michael D., Ellegaard, Martin Rene, Magnusson, Olafur þ., Sigurðsson, Ásgeir, Snorradóttir, Steinunn, Magnúsdóttir, Droplaug N., Laffoon, Jason, van Dorp, Lucy, Liu, Xiaodong, Moltke, Ida, Ávila-Arcos, María C., Schraiber, Joshua G., Rasmussen,Simon, Juan, David, Gelabert, Pere, De-Dios, Toni, Fotakis, Anna K., Iraeta-Orbegozo, Miren, Vågene, Åshild J., Dexter Denham, Sean, Christophersen, Axel, Stenøien, Hans K., Vieira, Filipe Garrett, Liu, Shanlin, Günther, Torsten, Kivisild, Toomas, Moseng, Ole Georg, Skar, Birgitte, Cheung, Christina, Sandoval-Velasco, Marcela, Wales, Nathan, Schroeder, Hannes, Campos, Paula F., Guðmundsdóttir, Valdís B., Sicheritz-Ponten, Thomas, Petersen, Bent, Halgunset, Jostein, Gilbert, Edmund, Cavalleri, Gianpiero L., Hovig, Eivind, Kockum, Ingrid, Olsson, Tomas, Alfredsson, Lars, Hansen, Thomas F., Werge, Thomas, Willerslev, Eske, Balloux, François, Marqués-Bonet, Tomàs, Lalueza-Fox, Carles, Nielsen, Rasmus, Stefánsson, Kári, Helgason, Agnar, Gilbert, M. Thomas P., Carlsberg Foundation, Danish National Research Foundation, Lundbeck Foundation, European Research Council, Research Council of Norway, Science Foundation Ireland, Gopalakrishnan, Shyam, Ebenesersdóttir, Sigríður Sunna, Lundstrøm, Inge K.C., Turner-Walker, Gordon, Moore, Kristjan H.S., Luisi, Pierre, Margaryan, Ashot, Martin, Michael D., Ellegaard, Martin Rene, Magnusson, Olafur þ., Sigurðsson, Ásgeir, Snorradóttir, Steinunn, Magnúsdóttir, Droplaug N., Laffoon, Jason, van Dorp, Lucy, Liu, Xiaodong, Moltke, Ida, Ávila-Arcos, María C., Schraiber, Joshua G., Rasmussen,Simon, Juan, David, Gelabert, Pere, De-Dios, Toni, Fotakis, Anna K., Iraeta-Orbegozo, Miren, Vågene, Åshild J., Dexter Denham, Sean, Christophersen, Axel, Stenøien, Hans K., Vieira, Filipe Garrett, Liu, Shanlin, Günther, Torsten, Kivisild, Toomas, Moseng, Ole Georg, Skar, Birgitte, Cheung, Christina, Sandoval-Velasco, Marcela, Wales, Nathan, Schroeder, Hannes, Campos, Paula F., Guðmundsdóttir, Valdís B., Sicheritz-Ponten, Thomas, Petersen, Bent, Halgunset, Jostein, Gilbert, Edmund, Cavalleri, Gianpiero L., Hovig, Eivind, Kockum, Ingrid, Olsson, Tomas, Alfredsson, Lars, Hansen, Thomas F., Werge, Thomas, Willerslev, Eske, Balloux, François, Marqués-Bonet, Tomàs, Lalueza-Fox, Carles, Nielsen, Rasmus, Stefánsson, Kári, Helgason, Agnar, and Gilbert, M. Thomas P.
- Abstract
Human populations have been shaped by catastrophes that may have left long-lasting signatures in their genomes. One notable example is the second plague pandemic that entered Europe in ca. 1,347 CE and repeatedly returned for over 300 years, with typical village and town mortality estimated at 10%–40%.1 It is assumed that this high mortality affected the gene pools of these populations. First, local population crashes reduced genetic diversity. Second, a change in frequency is expected for sequence variants that may have affected survival or susceptibility to the etiologic agent (Yersinia pestis).2 Third, mass mortality might alter the local gene pools through its impact on subsequent migration patterns. We explored these factors using the Norwegian city of Trondheim as a model, by sequencing 54 genomes spanning three time periods: (1) prior to the plague striking Trondheim in 1,349 CE, (2) the 17th–19th century, and (3) the present. We find that the pandemic period shaped the gene pool by reducing long distance immigration, in particular from the British Isles, and inducing a bottleneck that reduced genetic diversity. Although we also observe an excess of large FST values at multiple loci in the genome, these are shaped by reference biases introduced by mapping our relatively low genome coverage degraded DNA to the reference genome. This implies that attempts to detect selection using ancient DNA (aDNA) datasets that vary by read length and depth of sequencing coverage may be particularly challenging until methods have been developed to account for the impact of differential reference bias on test statistics.
- Published
- 2022
39. Bioarchaeological evidence of one of the earliest Islamic burials in the Levant
- Author
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Uppsala University, Srigyan, Megha, Bolívar, Héctor, Ureña, Irene, Santana, Jonathan, Petersen, Andrew, Iriarte, Eneko, Kırdök, Emrah, Bergfeldt, Nora, Mora, Alice, Jakobsson, Mattias, Abdo, Khaled, Braemer, Frank, Smith, Colin, Ibáñez-Estévez, Juan José, Götherström, Anders, Günther, Torsten, Valdiosera, Cristina, Uppsala University, Srigyan, Megha, Bolívar, Héctor, Ureña, Irene, Santana, Jonathan, Petersen, Andrew, Iriarte, Eneko, Kırdök, Emrah, Bergfeldt, Nora, Mora, Alice, Jakobsson, Mattias, Abdo, Khaled, Braemer, Frank, Smith, Colin, Ibáñez-Estévez, Juan José, Götherström, Anders, Günther, Torsten, and Valdiosera, Cristina
- Abstract
The Middle East plays a central role in human history harbouring a vast diversity of ethnic, cultural and religious groups. However, much remains to be understood about past and present genomic diversity in this region. Here we present a multidisciplinary bioarchaeological analysis of two individuals dated to the late 7th and early 8th centuries, the Umayyad Era, from Tell Qarassa, an open-air site in modern-day Syria. Radiocarbon dates and burial type are consistent with one of the earliest Islamic Arab burials in the Levant. Interestingly, we found genomic similarity to a genotyped group of modern-day Bedouins and Saudi rather than to most neighbouring Levantine groups. This study represents the genomic analysis of a secondary use site with characteristics consistent with an early Islamic burial in the Levant. We discuss our findings and possible historic scenarios in the light of forces such as genetic drift and their possible interaction with religious and cultural processes (including diet and subsistence practices).
- Published
- 2022
40. Ancient DNA from a 2700-year-old goitered gazelle ( Gazella subgutturosa ) supports gazelle hunting in Iron Age Central Asia
- Author
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Rodrigues Soares, André Elias, primary, Boroffka, Nikolaus, additional, Schröder, Oskar, additional, Sverchkov, Leonid, additional, Benecke, Norbert, additional, and Günther, Torsten, additional
- Published
- 2022
- Full Text
- View/download PDF
41. Multidisciplinary investigation reveals an individual of West African origin buried in a Portuguese Mesolithic shell midden four centuries ago
- Author
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Peyroteo-Stjerna, Rita, primary, Simões, Luciana G., additional, Fernandes, Ricardo, additional, Lopes, Gonçalo, additional, Günther, Torsten, additional, and Jakobsson, Mattias, additional
- Published
- 2022
- Full Text
- View/download PDF
42. Supplementary Material from Ancient DNA from a 2700-year-old goitered gazelle (Gazella subgutturosa) supports gazelle hunting in Iron Age Central Asia
- Author
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Rodrigues Soares, André Elias, Boroffka, Nikolaus, Schröder, Oskar, Sverchkov, Leonid, Benecke, Norbert, and Günther, Torsten
- Abstract
Supplementary Material
- Published
- 2022
- Full Text
- View/download PDF
43. Ancient DNA from a 2,700-year-old goitered gazelle (Gazella subgutturosa) confirms gazelle hunting in Iron Age Central Asia
- Author
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Rodrigues Soares, André Elias, primary, Boroffka, Nikolaus, additional, Schröder, Oskar, additional, Sverchkov, Leonid, additional, Benecke, Norbert, additional, and Günther, Torsten, additional
- Published
- 2021
- Full Text
- View/download PDF
44. Water yam (Dioscorea alata L.) diversity pattern in Brazil: an analysis with SSR and morphological markers
- Author
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Siqueira, Marcos V. B. M., Bonatelli, Maria L., Günther, Torsten, Gawenda, Inka, Schmid, Karl J., Pavinato, Vitor A. C., and Veasey, Elizabeth A.
- Published
- 2014
- Full Text
- View/download PDF
45. Genome of Peştera Muierii skull shows high diversity and low mutational load in pre-glacial Europe
- Author
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Svensson, Emma, primary, Günther, Torsten, additional, Hoischen, Alexander, additional, Hervella, Montserrat, additional, Munters, Arielle R., additional, Ioana, Mihai, additional, Ridiche, Florin, additional, Edlund, Hanna, additional, van Deuren, Rosanne C., additional, Soficaru, Andrei, additional, de-la-Rua, Concepción, additional, Netea, Mihai G., additional, and Jakobsson, Mattias, additional
- Published
- 2021
- Full Text
- View/download PDF
46. Genome of Pesxtera Muierii skull shows high diversity and low mutational load in pre-glacial Europe
- Author
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Genética, antropología física y fisiología animal, Genetika,antropologia fisikoa eta animalien fisiologia, Svensson, Emma, Günther, Torsten, Hoischen, Alexander, Hervella Afonso, Montserrat, Munters, Arielle R., Ioana, Mihai, Ridiche, Florin, Edlund, Hanna, Van Deuren, Rosanne C., Soficaru, Andrei, De la Rúa Vaca, Concepción, Netea, Mihai G., Jakobsson, Mattias, Genética, antropología física y fisiología animal, Genetika,antropologia fisikoa eta animalien fisiologia, Svensson, Emma, Günther, Torsten, Hoischen, Alexander, Hervella Afonso, Montserrat, Munters, Arielle R., Ioana, Mihai, Ridiche, Florin, Edlund, Hanna, Van Deuren, Rosanne C., Soficaru, Andrei, De la Rúa Vaca, Concepción, Netea, Mihai G., and Jakobsson, Mattias
- Abstract
Few complete human genomes from the European Early Upper Palaeolithic (EUP) have been sequenced. Using novel sampling and DNA extraction approaches, we sequenced the genome of a woman from "Pesxtera Muierii,"Romania who lived similar to 34,000 years ago to 13.5x coverage. The genome shows similarities to modern-day Europeans, but she is not a direct ancestor. Although her cranium exhibits both modern human and Neanderthal features, the genome shows similar levels of Neanderthal admixture (similar to 3.1%) to most EUP humans but only half compared to the similar to 40,000-year-old Pesxtera Oase 1. All EUP European hunter-gatherers display high genetic diversity, demonstrating that the severe loss of diversity occurred during and after the Last Glacial Maximum (LGM) rather than just during the out-of-Africa migration. The prevalence of genetic diseases is expected to increase with low diversity; however, pathogenic variant load was relatively constant from EUP to modern times, despite post-LGM hunter-gatherers having the lowest diversity ever observed among Europeans.
- Published
- 2021
47. Archaeogenetic analysis of Neolithic sheep from Anatolia suggests a complex demographic history since domestication
- Author
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One Health Toxicologie, Yurtman, Erinç, Özer, Onur, Yüncü, Eren, Dağtaş, Nihan Dilşad, Koptekin, Dilek, Çakan, Yasin Gökhan, Özkan, Mustafa, Akbaba, Ali, Kaptan, Damla, Atağ, Gözde, Vural, Kıvılcım Başak, Gündem, Can Yümni, Martin, Louise, Kılınç, Gülşah Merve, Ghalichi, Ayshin, Açan, Sinan Can, Yaka, Reyhan, Sağlıcan, Ekin, Lagerholm, Vendela Kempe, Krzewińska, Maja, Günther, Torsten, Morell Miranda, Pedro, Pişkin, Evangelia, Şevketoğlu, Müge, Bilgin, C Can, Atakuman, Çiğdem, Erdal, Yılmaz Selim, Sürer, Elif, Altınışık, N Ezgi, Lenstra, Johannes A, Yorulmaz, Sevgi, Abazari, Mohammad Foad, Hoseinzadeh, Javad, Baird, Douglas, Bıçakçı, Erhan, Çevik, Özlem, Gerritsen, Fokke, Özbal, Rana, Götherström, Anders, Somel, Mehmet, Togan, İnci, Özer, Füsun, One Health Toxicologie, Yurtman, Erinç, Özer, Onur, Yüncü, Eren, Dağtaş, Nihan Dilşad, Koptekin, Dilek, Çakan, Yasin Gökhan, Özkan, Mustafa, Akbaba, Ali, Kaptan, Damla, Atağ, Gözde, Vural, Kıvılcım Başak, Gündem, Can Yümni, Martin, Louise, Kılınç, Gülşah Merve, Ghalichi, Ayshin, Açan, Sinan Can, Yaka, Reyhan, Sağlıcan, Ekin, Lagerholm, Vendela Kempe, Krzewińska, Maja, Günther, Torsten, Morell Miranda, Pedro, Pişkin, Evangelia, Şevketoğlu, Müge, Bilgin, C Can, Atakuman, Çiğdem, Erdal, Yılmaz Selim, Sürer, Elif, Altınışık, N Ezgi, Lenstra, Johannes A, Yorulmaz, Sevgi, Abazari, Mohammad Foad, Hoseinzadeh, Javad, Baird, Douglas, Bıçakçı, Erhan, Çevik, Özlem, Gerritsen, Fokke, Özbal, Rana, Götherström, Anders, Somel, Mehmet, Togan, İnci, and Özer, Füsun
- Published
- 2021
48. Disentangling adaptation from drift in bottlenecked and reintroduced populations of Alpine ibex
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Leigh, Deborah M., Lischer, Heidi E. L., Guillaume, Frédéric, Grossen, Christine, Günther, Torsten, Leigh, Deborah M., Lischer, Heidi E. L., Guillaume, Frédéric, Grossen, Christine, and Günther, Torsten
- Abstract
dentifying local adaptation in bottlenecked species is essential for conservation man-agement. Selection detection methods have an important role in species management plans, assessments of adaptive capacity, and looking for responses to climate change. Yet, the allele frequency changes exploited in selection detection methods are similar to those caused by the strong neutral genetic drift expected during a bottleneck. Consequently, it is often unclear what accuracy selection detection methods have across bottlenecked populations. In this study, simulations were used to explore if signals of selection could be confidently distinguished from genetic drift across 23 bottlenecked and reintroduced populations of Alpine ibex (Capra ibex). The meticu-lously recorded demographic history of the Alpine ibex was used to generate compre-hensive simulated SNP data. The simulated SNPs were then used to benchmark the confidence we could place in outliers identified in empirical Alpine ibex RADseq de-rived SNP data. Within the simulated data set, the false positive rates were high for all selection detection methods (FST outlier scans and Genetic-Environment Association analyses) but fell substantially when two or more methods were combined. True posi-tive rates were consistently low and became negligible with increased stringency. Despite finding many outlier loci in the empirical Alpine ibex SNPs, none could be distinguished from genetic drift-driven false positives. Unfortunately, the low true positive rate also prevents the exclusion of recent local adaptation within the Alpine ibex. The baselines and stringent approach outlined here should be applied to other bottlenecked species to ensure the risk of false positive, or negative, signals of selec-tion are accounted for in conservation management plans.
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- 2021
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49. Genome of Pesxtera Muierii skull shows high diversity and low mutational load in pre-glacial Europe
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Svensson, Emma, Günther, Torsten, Hoischen, Alexander, Hervella, Montserrat, Munters, Arielle, Ioana, Mihai, Ridiche, Florin, Edlund, Hanna, van Deuren, Rosanne C., Soficaru, Andrei, De-la-Rua, Concepcion, Netea, Mihai G., Jakobsson, Mattias, Svensson, Emma, Günther, Torsten, Hoischen, Alexander, Hervella, Montserrat, Munters, Arielle, Ioana, Mihai, Ridiche, Florin, Edlund, Hanna, van Deuren, Rosanne C., Soficaru, Andrei, De-la-Rua, Concepcion, Netea, Mihai G., and Jakobsson, Mattias
- Abstract
Few complete human genomes from the European Early Upper Palaeolithic (EUP) have been sequenced. Using novel sampling and DNA extraction approaches, we sequenced the genome of a woman from "Pesxtera Muierii,"Romania who lived similar to 34,000 years ago to 13.5x coverage. The genome shows similarities to modern-day Europeans, but she is not a direct ancestor. Although her cranium exhibits both modern human and Neanderthal features, the genome shows similar levels of Neanderthal admixture (similar to 3.1%) to most EUP humans but only half compared to the similar to 40,000-year-old Pesxtera Oase 1. All EUP European hunter-gatherers display high genetic diversity, demonstrating that the severe loss of diversity occurred during and after the Last Glacial Maximum (LGM) rather than just during the out-of-Africa migration. The prevalence of genetic diseases is expected to increase with low diversity; however, pathogenic variant load was relatively constant from EUP to modern times, despite post-LGM hunter-gatherers having the lowest diversity ever observed among Europeans.
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- 2021
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50. Variable kinship patterns in Neolithic Anatolia revealed by ancient genomes
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Yaka, Reyhan, Mapelli, Igor, Kaptan, Damla, Dogu, Ayca, Chylenski, Maciej, Erdal, Ömür Dilek, Koptekin, Dilek, Vural, Kivilcim Basak, Bayliss, Alex, Mazzucato, Camilla, Fer, Evrim, Cokoglu, Sevim Seda, Kempe Lagerholm, Vendela, Krzewinska, Maja, Karamurat, Cansu, Gemici, Hasan Can, Sevkar, Arda, Dagtas, Nihan Dilsad, Kilinc, Gülsah Merve, Adams, Donovan, Munters, Arielle R., Saglican, Ekin, Milella, Marco, Schotsmans, Eline M. J., Yurtman, Erinc, Cetin, Mehmet, Yorulmaz, Sevgi, Altinisik, N. Ezgi, Ghalichi, Ayshin, Juras, Anna, Bilgin, C. Can, Günther, Torsten, Storå, Jan, Jakobsson, Mattias, de Kleijn, Maurice, Mustafaoglu, Gökhan, Fairbairn, Andrew, Pearson, Jessica, Togan, Inci, Kayacan, Nurcan, Marciniak, Arkadiusz, Larsen, Clark Spencer, Hodder, Ian, Atakuman, Cigdem, Pilloud, Marin, Sürer, Elif, Gerritsen, Fokke, Özbal, Rana, Baird, Douglas, Erdal, Yilmaz Selim, Duru, Günes, Özbasaran, Mihriban, Haddow, Scott D., Knüsel, Christopher J., Götherström, Anders, Özer, Füsun, Somel, Mehmet, Yaka, Reyhan, Mapelli, Igor, Kaptan, Damla, Dogu, Ayca, Chylenski, Maciej, Erdal, Ömür Dilek, Koptekin, Dilek, Vural, Kivilcim Basak, Bayliss, Alex, Mazzucato, Camilla, Fer, Evrim, Cokoglu, Sevim Seda, Kempe Lagerholm, Vendela, Krzewinska, Maja, Karamurat, Cansu, Gemici, Hasan Can, Sevkar, Arda, Dagtas, Nihan Dilsad, Kilinc, Gülsah Merve, Adams, Donovan, Munters, Arielle R., Saglican, Ekin, Milella, Marco, Schotsmans, Eline M. J., Yurtman, Erinc, Cetin, Mehmet, Yorulmaz, Sevgi, Altinisik, N. Ezgi, Ghalichi, Ayshin, Juras, Anna, Bilgin, C. Can, Günther, Torsten, Storå, Jan, Jakobsson, Mattias, de Kleijn, Maurice, Mustafaoglu, Gökhan, Fairbairn, Andrew, Pearson, Jessica, Togan, Inci, Kayacan, Nurcan, Marciniak, Arkadiusz, Larsen, Clark Spencer, Hodder, Ian, Atakuman, Cigdem, Pilloud, Marin, Sürer, Elif, Gerritsen, Fokke, Özbal, Rana, Baird, Douglas, Erdal, Yilmaz Selim, Duru, Günes, Özbasaran, Mihriban, Haddow, Scott D., Knüsel, Christopher J., Götherström, Anders, Özer, Füsun, and Somel, Mehmet
- Abstract
The social organization of the first fully sedentary societies that emerged during the Neolithic period in Southwest Asia remains enigmatic,(1) mainly because material culture studies provide limited insight into this issue. However, because Neolithic Anatolian communities often buried their dead beneath domestic buildings,(2) household composition and social structure can be studied through these human remains. Here, we describe genetic relatedness among co-burials associated with domestic buildings in Neolithic Anatolia using 59 ancient genomes, including 22 new genomes from Asxikli Hoyuk and Catalhoyuk. We infer pedigree relationships by simultaneously analyzing multiple types of information, including autosomal and X chromosome kinship coefficients, maternal markers, and radiocarbon dating. In two early Neolithic villages dating to the 9th and 8th millennia BCE, Asxikli Hoyuk and Boncuklu, we discover that siblings and parent-offspring pairings were frequent within domestic structures, which provides the first direct indication of close genetic relationships among co-burials. In contrast, in the 7th millennium BCE sites of Catalhoyuk and Barcin, where we study subadults interred within and around houses, we find close genetic relatives to be rare. Hence, genetic relatedness may not have played a major role in the choice of burial location at these latter two sites, at least for subadults. This supports the hypothesis that in Catalhoyuk,(3-5) and possibly in some other Neolithic communities, domestic structures may have served as burial location for social units incorporating biologically unrelated individuals. Our results underscore the diversity of kin structures in Neolithic communities during this important phase of sociocultural development.
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- 2021
- Full Text
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