66 results on '"Gruszczyńska K"'
Search Results
2. Computed tomography in the evaluation of the anomalous origin of the coronary artery: coexistence with other congenital heart disease in an adult population
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Krupiński, M., primary, Urbańczyk-Zawadzka, M., additional, Laskowicz, B., additional, Irzyk, M., additional, Banyś, R., additional, Gruszczyńska, K., additional, and Baron, J., additional
- Published
- 2015
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3. 1114 The number of short-axis series for MR left ventricular analysis can be reduced when a combined long-axis and short-axis analysis strategy is used
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Krestin Gabriel P, Cova Maria A, Moelker Adriaan, Gruszczynska Katarzyna, Kirschbaum Sharon WM, Rossi Alexia, de Feijter Pim J, and van Geuns Robert JM
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Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Published
- 2008
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4. Reliability of inter-recti distance measurement on ultrasound images captured by novice examiners.
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Chmielewska D, Cebula M, Gnat R, Rudek-Zeprzałka M, Gruszczyńska K, Baron J, and Opala-Berdzik A
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- Humans, Reproducibility of Results, Female, Adult, Young Adult, Umbilicus diagnostic imaging, Clinical Competence, Predictive Value of Tests, Anatomic Landmarks, Ultrasonography methods, Observer Variation
- Abstract
Background: With the increased interest in inter-recti distance measurement using ultrasound imaging in physiotherapy, there is a question of measurement reliability, and the importance of the examiner's experience., Purpose: The study aimed to investigate the reliability of inter-recti distance measurement in a DICOM viewer software by an experienced radiologist. For the measurement, the radiologist used linea alba images captured by two physiotherapists who were novice examiners., Methods: Ultrasound images were acquired by two novice examiners on repeated occasions 7 days apart (sessions A and B) in 28 nulliparous women at supraumbilical, umbilical, and infraumbilical locations along linea alba., Results: Excellent intra-examiner reliability of inter-recti distance measurements was shown at the supraumbilical and umbilical levels (ICC
2,k = 0.941-0.983) with minimal detectable change (MDC95 ) ranging from 1.31 mm to 2.29 mm. Infraumbilical measurements had good to excellent reliability (ICC2,k = 0.894-0.972) with MDC95 ranging from 0.33 mm to 0.72 mm. Session A inter-examiner reliability was excellent for the mean measurements of two, three, four, and five images taken at each location (ICC2,k = 0.913-0.954) with MDC95 ranging from 0.47 mm to 2.96 mm. Session B inter-examiner reliability was excellent for the mean measurements of two, three, four, and five images taken at the supraumbilical and umbilical (ICC2,k = 0.94-0.98), MDC95 ranging from 1.38 mm to 2.58 mm and good (ICC2,k ≥ 0.81) with MDC95 ranging from 0.72 mm to 0.80 mm at the infraumbilical locations., Conclusion: Novice examiners were able to capture good-quality ultrasound images of the linea alba that allowed for good to excellent intra- and inter-examiner reliability.- Published
- 2024
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5. Measurement of Cardiothoracic Ratio on Chest X-rays Using Artificial Intelligence-A Systematic Review and Meta-Analysis.
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Kufel J, Czogalik Ł, Bielówka M, Magiera M, Mitręga A, Dudek P, Bargieł-Łączek K, Stencel M, Bartnikowska W, Mielcarska S, Modlińska S, Nawrat Z, Cebula M, and Gruszczyńska K
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Background: Chest X-rays (CXRs) are pivotal in clinical diagnostics, particularly in assessing cardiomegaly through the cardiothoracic ratio (CTR). This systematic review and meta-analysis evaluate the efficacy of artificial intelligence (AI) in automating CTR determination to enhance patient care and streamline diagnostic processes. They are concentrated on comparing the performance of AI models in determining the CTR against human assessments, identifying the most effective models for potential clinical implementation. This study was registered with PROSPERO (no. CRD42023437459). No funding was received. Methods: A comprehensive search of medical databases was conducted in June 2023. The search strategy adhered to the PICO framework. Inclusion criteria encompassed original articles from the last decade focusing on AI-assisted CTR assessment from standing-position CXRs. Exclusion criteria included systematic reviews, meta-analyses, conference abstracts, paediatric studies, non-original articles, and studies using imaging techniques other than X-rays. After initial screening, 117 articles were reviewed, with 14 studies meeting the final inclusion criteria. Data extraction was performed by three independent investigators, and quality assessment followed PRISMA 2020 guidelines, using tools such as the JBI Checklist, AMSTAR 2, and CASP Diagnostic Study Checklist. Risk of bias was assessed according to the Cochrane Handbook guidelines. Results: Fourteen studies, comprising a total of 70,472 CXR images, met the inclusion criteria. Various AI models were evaluated, with differences in dataset characteristics and AI technology used. Common preprocessing techniques included resizing and normalization. The pooled AUC for cardiomegaly detection was 0.959 (95% CI 0.944-0.975). The pooled standardized mean difference for CTR measurement was 0.0353 (95% CI 0.147-0.0760). Significant heterogeneity was found between studies (I
2 89.97%, p < 0.0001), with no publication bias detected. Conclusions: Standardizing methodologies is crucial to avoid interpretational errors and advance AI in medical imaging diagnostics. Uniform reporting standards are essential for the further development of AI in CTR measurement and broader medical imaging applications.- Published
- 2024
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6. Deep Learning in Cardiothoracic Ratio Calculation and Cardiomegaly Detection.
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Kufel J, Paszkiewicz I, Kocot S, Lis A, Dudek P, Czogalik Ł, Janik M, Bargieł-Łączek K, Bartnikowska W, Koźlik M, Cebula M, Gruszczyńska K, and Nawrat Z
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Objectives : The purpose of this study is to evaluate the performance of our deep learning algorithm in calculating cardiothoracic ratio (CTR) and thus in the assessment of cardiomegaly or pericardial effusion occurrences on chest radiography (CXR). Methods : From a database of 8000 CXRs, 13 folders with a comparable number of images were created. Then, 1020 images were chosen randomly, in proportion to the number of images in each folder. Afterward, CTR was calculated using RadiAnt Digital Imaging and Communications in Medicine (DICOM) Viewer software (2023.1). Next, heart and lung anatomical areas were marked in 3D Slicer. From these data, we trained an AI model which segmented heart and lung anatomy and determined the CTR value. Results : Our model achieved an Intersection over Union metric of 88.28% for the augmented training subset and 83.06% for the validation subset. F1-score for subsets were accordingly 90.22% and 90.67%. In the comparative analysis of artificial intelligence (AI) vs. humans, significantly lower transverse thoracic diameter (TTD) ( p < 0.001), transverse cardiac diameter (TCD) ( p < 0.001), and CTR ( p < 0.001) values obtained using the neural network were observed. Conclusions : Results confirm that there is a significant correlation between the measurements made by human observers and the neural network. After validation in clinical conditions, our method may be used as a screening test or advisory tool when a specialist is not available, especially on Intensive Care Units (ICUs) or Emergency Departments (ERs) where time plays a key role.
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- 2024
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7. Work-Related Quality of Life among Physicians in Poland: A Cross-Sectional Study.
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Jakimów K, Ciesielka J, Bonczek M, Rak J, Matlakiewicz M, Majewska K, Gruszczyńska K, and Winder M
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Background and Objectives: Working in a healthcare setting is associated with high levels of stress and burnout syndrome. Work-related quality of life (WRQoL) remains insufficiently evaluated among physicians. The aim of this study is to assess the WRQoL among physicians of interventional, non-interventional, and diagnostic specialties in Poland., Materials and Methods: Standardized and anonymous WRQoL questionnaires have been filled in by 257 physicians working in Silesia, Poland. After the removal of missing data, 246 individuals were stratified in terms of specialties into the appropriate categories, including interventional, non-interventional, and diagnostics. These categories were compared using the following subscales: general well-being (GWB), home-work interface (HWI), job and career satisfaction (JCS), control at work (CAW), working conditions (WCS), and stress at work (SAW)., Results: Out of 246 individuals, 132 were women (53.7%) and 112 (45.5%) were men. There were no differences in terms of WRQoL scores ( p = 0.220) and subscales GWB ( p = 0.148), HWI ( p = 0.368), JCS ( p = 0.117), CAW ( p = 0.224), WCS ( p = 0.609), SAW ( p = 0.472) between interventional, non-interventional, and diagnostic specialties. The group of young doctors (age ≤ 30 years) had higher JCS scores than the older ones (mean score [SD], 22.7 [3.98] vs. 21 [4.6]; p = 0.013). Physicians who were not working in hospital had higher WRQoL score than respondents working in hospital ( p = 0.061), with significant differences in terms of GWB (mean score [SD], 20.3 [4.93] vs. 22.8 [3.2], p = 0.014), HWI (mean score [SD], 9.1 [=2.65] vs. 10.6 [2.73], p = 0.011), and WCS (mean score [SD], 9.5 [2.61] vs. 10.8 [2.54], p = 0.035)., Conclusion: There were no differences considering overall WRQoL between analyzed groups stratified according to specialty. However, we disclosed a significant association between the respondent's WRQoL and age as well as place of work.
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- 2024
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8. Evaluation of Various Methods of Liver Measurement in Comparison to Volumetric Segmentation Based on Computed Tomography.
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Cebula M, Biernacka A, Bożek O, Kokoszka B, Kazibut S, Kujszczyk A, Kulig-Kulesza M, Modlińska S, Kufel J, Azierski M, Szydło F, Winder M, Pilch-Kowalczyk J, and Gruszczyńska K
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Background : A reliable assessment of liver volume, necessary before transplantation, remains a challenge. Our work aimed to assess the differences in the evaluation and measurements of the liver between independent observers and compare different formulas calculating its volume in relation to volumetric segmentation. Methods : Eight researchers measured standard liver dimensions based on 105 abdominal computed tomography (CT) scans. Based on the results obtained, the volume of the liver was calculated using twelve different methods. An independent observer performed a volumetric segmentation of the livers based on the same CT examinations. Results : Significant differences were found between the formulas and in relation to volumetric segmentation, with the closest results obtained for the Heinemann et al. method. The measurements of individual observers differed significantly from one another. The observers also rated different numbers of livers as enlarged. Conclusions : Due to significant differences, despite its time-consuming nature, the use of volumetric liver segmentation in the daily assessment of liver volume seems to be the most accurate method.
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- 2024
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9. Influence of the physical pressure of an ultrasound probe on shear-wave elastography measurements of the gastrocnemius muscle in a paediatric population: a non-interventional cohort study.
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Cebula A, Cebula M, Czajkowska M, Gruszczyńska K, and Kopyta I
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Purpose: The aim of our study is to evaluate the impact of ultrasound probe mechanical pressure on the stiffness of the gastrocnemius muscle in a healthy paediatric population. As far as we know, there has been no previous qualitative in vivo study on the impact of probe pressure on muscle shear-wave elastography results with objective evaluation of compression in the paediatric population., Material and Methods: In this cohort study, a group of 22 children (mean age 8.99 years, SD 2.74, 11 males) underwent elastography of the gastrocnemius muscle of the dominant leg. A custom-made, 3-dimensional printed probe cover was used to measure the mechanical pressure of the probe on tissues., Results: The obtained results were related to the age, sex, BMI, and calf circumference of the subjects. We observed a significant difference in the stiffness parameter at a pressure of 1 N, with a further increase if force was increased ( p < 0.001). A significant, very weak positive correlation of age and stiffness was observed ( p < 0.001, r
2 = 0.022). There was no significant correlation of stiffness, BMI, and calf circumference., Conclusions: The use of compression during muscle elastography in children causes a significant bias in results, regardless of age, sex, BMI, or calf size., Competing Interests: The authors report no conflicts of interest., (© Pol J Radiol 2024.)- Published
- 2024
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10. Mobile applications in radiology: own study based on polish data.
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Kufel J, Bargieł K, Koźlik M, Bartnikowska W, Janik M, Czogalik Ł, Dudek P, Krawczyk D, Magiera M, Cebula M, Nawrat Z, and Gruszczyńska K
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- Humans, Poland, Smartphone, Mobile Applications, Radiology
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As the number of smartphones increases, so does the number of medical apps. Medical mobile applications are widely used in many medical fields by both patients and doctors. However, there are still few approved mobile applications that can be used in the diagnostic-therapeutic process and radiological apps are affected as well. We conducted our research by classifying radiological applications from the Google Play® store into appropriate categories, according to our own qualification system developed by researchers for the purposes of this study. In addition, we also evaluated apps from the App Store®. The radiology application rating system we created has not been previously used in other articles. Out of 228 applications from the Google Play store, only 6 of them were classified as "A" category with the highest standard. Apps from the App Store (157) were not categorized due to the lack of download counts, which was necessary in our app-rating system. The vast majority of applications are for educational purposes and are not used in clinical practice. This is due to the need of obtaining special permits and certificates from relevant institutions in order to use them in medical practice. We recommend applications from the Google Play store that have been classified in the "A" category, evaluating them as the most valuable. App Store apps data is described and presented in the form of diagrams and tables., (© 2023. The Author(s).)
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- 2023
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11. Multi-Label Classification of Chest X-ray Abnormalities Using Transfer Learning Techniques.
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Kufel J, Bielówka M, Rojek M, Mitręga A, Lewandowski P, Cebula M, Krawczyk D, Bielówka M, Kondoł D, Bargieł-Łączek K, Paszkiewicz I, Czogalik Ł, Kaczyńska D, Wocław A, Gruszczyńska K, and Nawrat Z
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In recent years, deep neural networks have enabled countless innovations in the field of image classification. Encouraged by success in this field, researchers worldwide have demonstrated how to use Convolutional Neural Network techniques in medical imaging problems. In this article, the results were obtained through the use of the EfficientNet in the task of classifying 14 different diseases based on chest X-ray images coming from the NIH (National Institutes of Health) ChestX-ray14 dataset. The approach addresses dataset imbalances by introducing a custom split to ensure fair representation. Binary cross entropy loss is utilized to handle the multi-label difficulty. The model architecture comprises an EfficientNet backbone for feature extraction, succeeded by sequential layers including GlobalAveragePooling, Dense, and BatchNormalization. The main contribution of this paper is a proposed solution that outperforms previous state-of-the-art deep learning models average area under the receiver operating characteristic curve-AUC-ROC (score: 84.28%). The usage of the transfer-learning technique and traditional deep learning engineering techniques was shown to enable us to obtain such results on consumer-class GPUs (graphics processing units).
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- 2023
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12. Will ChatGPT pass the Polish specialty exam in radiology and diagnostic imaging? Insights into strengths and limitations.
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Kufel J, Paszkiewicz I, Bielówka M, Bartnikowska W, Janik M, Stencel M, Czogalik Ł, Gruszczyńska K, and Mielcarska S
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Purpose: Rapid development of artificial intelligence has aroused curiosity regarding its potential applications in medical field. The purpose of this article was to present the performance of ChatGPT, a state-of-the-art language model in relation to pass rate of national specialty examination (PES) in radiology and imaging diagnostics within Polish education system. Additionally, the study aimed to identify the strengths and limitations of the model through a detailed analysis of issues raised by exam questions., Material and Methods: The present study utilized a PES exam consisting of 120 questions, provided by Medical Exami-nations Center in Lodz. Questions were administered using openai.com platform that grants free access to GPT-3.5 model. All questions were categorized according to Bloom's taxonomy to assess their complexity and difficulty. Following the answer to each exam question, ChatGPT was asked to rate its confidence on a scale of 1 to 5 to evaluate the accuracy of its response., Results: ChatGPT did not reach the pass rate threshold of PES exam (52%); however, it was close in certain question categories. No significant differences were observed in the percentage of correct answers across question types and sub-types., Conclusions: The performance of the ChatGPT model in the pass rate of PES exam in radiology and imaging diagnostics in Poland is yet to be determined, which requires further research on improved versions of ChatGPT., Competing Interests: The authors report no conflict of interest., (© Pol J Radiol 2023.)
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- 2023
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13. Abbreviated magnetic resonance imaging protocols in oncology: improving accessibility in precise diagnostics.
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Grabowska S, Hitnarowicz A, Barczyk-Gutkowska A, Gruszczyńska K, Steinhof-Radwańska K, and Winder M
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Cancer, as the second leading cause of death in the world, is one of the major public health concerns today. Accurate diagnosis and prompt initiation of adequate treatment are of key importance for prognosis. Abbreviated magnetic resonance protocols (AMRI) are promising techniques based on magnetic resonance imaging (MRI) protocols that shorten acquisition time without significant loss of examination quality. Faster protocols that focus on detection of suspicious lesions with most precise sequences, can contribute to comparable diagnostic performance of a full MRI protocol. The purpose of this article was to review the current application of AMRI protocols in several oncological diseases., Competing Interests: The authors report no conflict of interest., (© Pol J Radiol 2023.)
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- 2023
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14. Chest X-ray Foreign Objects Detection Using Artificial Intelligence.
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Kufel J, Bargieł-Łączek K, Koźlik M, Czogalik Ł, Dudek P, Magiera M, Bartnikowska W, Lis A, Paszkiewicz I, Kocot S, Cebula M, Gruszczyńska K, and Nawrat Z
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Diagnostic imaging has become an integral part of the healthcare system. In recent years, scientists around the world have been working on artificial intelligence-based tools that help in achieving better and faster diagnoses. Their accuracy is crucial for successful treatment, especially for imaging diagnostics. This study used a deep convolutional neural network to detect four categories of objects on digital chest X-ray images. The data were obtained from the publicly available National Institutes of Health (NIH) Chest X-ray (CXR) Dataset. In total, 112,120 CXRs from 30,805 patients were manually checked for foreign objects: vascular port, shoulder endoprosthesis, necklace, and implantable cardioverter-defibrillator (ICD). Then, they were annotated with the use of a computer program, and the necessary image preprocessing was performed, such as resizing, normalization, and cropping. The object detection model was trained using the You Only Look Once v8 architecture and the Ultralytics framework. The results showed not only that the obtained average precision of foreign object detection on the CXR was 0.815 but also that the model can be useful in detecting foreign objects on the CXR images. Models of this type may be used as a tool for specialists, in particular, with the growing popularity of radiology comes an increasing workload. We are optimistic that it could accelerate and facilitate the work to provide a faster diagnosis.
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- 2023
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15. What Is Machine Learning, Artificial Neural Networks and Deep Learning?-Examples of Practical Applications in Medicine.
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Kufel J, Bargieł-Łączek K, Kocot S, Koźlik M, Bartnikowska W, Janik M, Czogalik Ł, Dudek P, Magiera M, Lis A, Paszkiewicz I, Nawrat Z, Cebula M, and Gruszczyńska K
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Machine learning (ML), artificial neural networks (ANNs), and deep learning (DL) are all topics that fall under the heading of artificial intelligence (AI) and have gained popularity in recent years. ML involves the application of algorithms to automate decision-making processes using models that have not been manually programmed but have been trained on data. ANNs that are a part of ML aim to simulate the structure and function of the human brain. DL, on the other hand, uses multiple layers of interconnected neurons. This enables the processing and analysis of large and complex databases. In medicine, these techniques are being introduced to improve the speed and efficiency of disease diagnosis and treatment. Each of the AI techniques presented in the paper is supported with an example of a possible medical application. Given the rapid development of technology, the use of AI in medicine shows promising results in the context of patient care. It is particularly important to keep a close eye on this issue and conduct further research in order to fully explore the potential of ML, ANNs, and DL, and bring further applications into clinical use in the future.
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- 2023
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16. The application of abbreviated MRI protocols in malignant liver lesions surveillance.
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Winder M, Grabowska S, Hitnarowicz A, Barczyk-Gutkowska A, Gruszczyńska K, and Steinhof-Radwańska K
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- Humans, Magnetic Resonance Imaging methods, Abdomen, Retrospective Studies, Contrast Media, Liver Neoplasms diagnostic imaging, Liver Neoplasms secondary, Carcinoma, Hepatocellular
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Cancer is one of the leading public health problems globally. Since time is of the essence in oncology, the sooner an accurate diagnosis is made, the better the prognosis for patients. There is a growing need to find a flawless and fast imaging method for cancer detection, but also for its evaluation during treatment. In this respect, the possibilities and novelties of magnetic resonance imaging are particularly promising. Abbreviated magnetic resonance imaging (AMRI) protocols have aroused universal interest as a compromise between scanning time reduction and preservation of image quality. Shorter protocols focused on the detection of suspicious lesions with the most sensitive sequences could provide a diagnostic performance similar to the one of the standard protocol. The purpose of this article is to review the ongoing accomplishments in the use of AMRI protocols in liver metastases and HCC detection., Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2023 The Author(s). Published by Elsevier B.V. All rights reserved.)
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- 2023
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17. A single-center, retrospective, cross-sectional study comparing the number of non-diagnostic measurements ratio in the pSWE and SSI ultrasound elastography methods.
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Cebula M, Kufel J, and Gruszczyńska K
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- Humans, Cross-Sectional Studies, Retrospective Studies, Reproducibility of Results, Liver diagnostic imaging, Liver pathology, Liver Cirrhosis diagnosis, Elasticity Imaging Techniques methods
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The point shear wave elastography and supersonic shear imaging methods were compared regarding incorrect measurements during the liver examinations. A report-based, single-center, retrospective analysis of 425 liver elastography examinations was performed. A lower success ratio was observed for the point shear wave elastography method, as well as the older and obese patients pre-dominated in non-diagnostic studies. In our center experience, it is easier to obtain diagnostic data using the supersonic shear imaging method. However, further investigation of the subject is needed., Competing Interests: The authors have no funding and conflicts of interest to disclose., (Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc.)
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- 2023
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18. Technical aspects of inter-recti distance measurement with ultrasonographic imaging for physiotherapy purposes: the scoping review.
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Opala-Berdzik A, Rudek-Zeprzałka M, Niesporek J, Cebula M, Baron J, Gruszczyńska K, Pascoal AG, Mota P, and Chmielewska D
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Background: Inter-recti distance (IRD) measurement using musculoskeletal USI has been used in physiotherapy research, in particular, to investigate pregnancy-related diastasis recti abdominis (DRA) and to seek its effective treatment methods. Severe and untreated diastasis may result in the formation of umbilical or epigastric hernias., Objective: This study aimed to systematically map physiotherapy-related research articles that included descriptions of IRD measurement procedures using USI to present their similarities and differences, and formulate recommendations on the procedure., Design: A scoping review was conducted according to PRISMA-ScR guidelines, including 49 of 511 publications from three major databases. Publications were selected and screened by two independent reviewers whose decisions were consulted with a third reviewer. The main synthesized data items were: the examinees' body position, breathing phase, measurement sites, and DRA screening methods. The final conclusions and recommendations were the result of a consensus between seven reviewers from four research centers., Results: Studies used 1-5 measurement sites that were differently determined. IRD was measured at the umbilicus (n = 3), at its superior (n = 16) and/or inferior border (n = 9), and at different levels: between 2 and 12 cm above the umbilicus, or a third of the distance and halfway between the umbilicus and xiphoid (n = 37); between 2 and 4.5 cm below the umbilicus or halfway between the umbilicus and pubis (n = 27). Different approaches were used to screen subjects for DRA., Conclusions: The discrepancies between the measurement procedures prevent between-study comparisons. The DRA screening method should be standardized. IRD measurement protocol standardization has been proposed., Critical Relevance Statement: This scoping review indicates that the inter-recti distance measurement procedures using ultrasound imaging differ between studies, preventing between-study comparisons. Based on the results synthesis, the measurement protocol standardization has been proposed., Key Points: The inter-recti distance measurement procedures using USI differ between studies. Proposed standardization concerns body position, breathing phase, measurements number per location. Determination of measurement locations considering individual linea alba length is suggested. Recommended locations: umbilical top, ½ of umbilical top-xiphoid, ¼ of umbilical top-xiphoid/pubis distances. Diastasis recti abdominis diagnostic criteria are needed for proposed measurement locations., (© 2023. The Author(s).)
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- 2023
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19. Encephalocraniocutaneous Lipomatosis, a Radiological Challenge: Two Atypical Case Reports and Literature Review.
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Machnikowska-Sokołowska M, Fabrowicz P, Pilch J, Roesler W, Kuźniak M, Gruszczyńska K, and Paprocka J
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Encephalocraniocutaneous lipomatosis (ECCL; Haberland syndrome, #613001) is an extremely rare congenital disorder that is manifested by the involvement of the skin, eyes and central nervous system (CNS). We report two cases of children with ECCL diagnosis. First was an 8-year-old girl who presented with symptomatic epilepsy, cerebral palsy and developmental delay. In 2020, she was admitted to the hospital due to the exacerbation of paresis and intensified prolonged epileptic seizures, provoked by infection of the middle ear. Diagnostic imaging revealed radiological changes suggestive of ECCL, providing a reason for the diagnosis, despite the lack of skin and eye anomalies. The second child, a 14-year-old girl, was consulted for subtle clinical signs and epilepsy suspicion. Diagnostic imaging findings were similar, though less pronounced. Based on neuroradiological abnormalities typical for Haberland syndrome, the authors discuss possible ECCL diagnosis.
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- 2022
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20. The Assessment of the Rationale for Urgent Head CT-Comparative Analysis of Referrals and Results of Examinations without and with Contrast Enhancement.
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Rosół I, Ciesielka J, Matlakiewicz M, Grześków M, Cebula M, Gruszczyńska K, and Winder M
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- Humans, Retrospective Studies, Workload, Tomography, X-Ray Computed methods, Referral and Consultation
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The study analyzes the correlation between the indications and results of head CT examinations in search of evidence of the excessive use of this diagnostic method. In total, 1160 referrals for urgent head CT were analyzed retrospectively, including the following parameters: patients' sex and age, type of scan (C-, C+, angio-CT), description of symptoms and presence of diagnostic target. Pathologies identified by the radiologist were assigned to four classes, regarding the severity of diagnosed conditions. The analysis of the CT results has shown that over half (55.22%) of the examinations revealed no deviations or showed chronic, asymptomatic lesions. As many as 73.71% referrals constituted group 0 in terms of the lack of a diagnostic target of a specific pathology. The presence of specific clinical targeting in a referral correlated significantly with a higher frequency of acute diagnosis. Contrast-enhanced follow-up examinations allowed the unequivocal classification of patients into extreme classes (I or IV) and accurate identification of patients requiring urgent or chronic treatment. Excessive use of diagnostic imaging is harmful, not only to patients, who often are unnecessarily exposed to radiation, but also to the quality of healthcare, since it increases the costs and radiologists' workload.
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- 2022
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21. Usability of Mobile Solutions Intended for Diagnostic Images-A Systematic Review.
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Kufel J, Bargieł K, Koźlik M, Czogalik Ł, Dudek P, Jaworski A, Magiera M, Bartnikowska W, Cebula M, Nawrat Z, and Gruszczyńska K
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Despite the growing popularity of mobile devices, they still have not found widespread use in medicine. This is due to the procedures in a given place, differences in the availability of mobile devices between individual institutions or lack of appropriate legal regulations and accreditation by relevant institutions. Numerous studies have been conducted and compared the usability of mobile solutions designed for diagnostic images evaluation on various mobile devices and applications with classic stationary descriptive stations. This study is an attempt to compare the usefulness of currently available mobile applications which are used in the medical industry, focusing on imaging diagnostics. As a consequence of the healthcare sector's diversity, it is also not possible to design a universal mobile application, which results in a multitude of software available on the market and makes it difficult to reliably compile and compare studies included in this systematic review. Despite these differences, it was possible to identify both positive and negative features of portable methods analyzing radiological images. The mobile application of the golden mean in hospital infrastructure should be widely available, with convenient and simple usage. Our future research will focus on development in the use of mobile devices and applications in the medical sector.
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- 2022
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22. Application of artificial intelligence in diagnosing COVID-19 disease symptoms on chest X-rays: A systematic review.
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Kufel J, Bargieł K, Koźlik M, Czogalik Ł, Dudek P, Jaworski A, Cebula M, and Gruszczyńska K
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- Humans, Artificial Intelligence, X-Rays, Sensitivity and Specificity, Radiography, COVID-19 diagnostic imaging
- Abstract
This systematic review focuses on using artificial intelligence (AI) to detect COVID-19 infection with the help of X-ray images. Methodology : In January 2022, the authors searched PubMed, Embase and Scopus using specific medical subject headings terms and filters. All articles were independently reviewed by two reviewers. All conflicts resulting from a misunderstanding were resolved by a third independent researcher. After assessing abstracts and article usefulness, eliminating repetitions and applying inclusion and exclusion criteria, six studies were found to be qualified for this study. Results : The findings from individual studies differed due to the various approaches of the authors. Sensitivity was 72.59%-100%, specificity was 79%-99.9%, precision was 74.74%-98.7%, accuracy was 76.18%-99.81%, and the area under the curve was 95.24%-97.7%. Conclusion : AI computational models used to assess chest X-rays in the process of diagnosing COVID-19 should achieve sufficiently high sensitivity and specificity. Their results and performance should be repeatable to make them dependable for clinicians. Moreover, these additional diagnostic tools should be more affordable and faster than the currently available procedures. The performance and calculations of AI-based systems should take clinical data into account., Competing Interests: Competing Interests: The authors have declared that no competing interest exists., (© The author(s).)
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- 2022
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23. Intestinal Elastography in the Diagnostics of Ulcerative Colitis: A Narrative Review.
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Cebula M, Kufel J, Grażyńska A, Habas J, and Gruszczyńska K
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Ulcerative colitis (UC) is an inflammatory bowel disease (IBD) that mainly affects developed countries, but the number of cases in developing countries is increasing. We conducted a narrative review on the potential application of ultrasound elastography in the diagnosis and monitoring of UC, as this newly emerging method has promising results in other gut diseases. This review fulfilled the PRISMA Statement criteria with a time cut-off of June 2022. At the end of the review, of the 1334 identified studies, only five fulfilled all the inclusion criteria. Due to the small number of studies in this field, a reliable assessment of the usefulness of ultrasound elastography is difficult. We can only conclude that the transabdominal elastography examination did not significantly differ from the standard gastrointestinal ultrasonography examination and that measurements of the frontal intestinal wall should be made in the longitudinal section. The reports suggest that it is impossible to estimate the clinical scales used in disease assessment solely on the basis of elastographic measurements. Due to the different inclusion criteria, measurement methodologies, and elastographic techniques used in the analysed studies, a reliable comparative evaluation was impossible. Further work is required to assess the validity of expanding gastrointestinal ultrasonography with elastography in the diagnosis and monitoring of UC.
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- 2022
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24. Indications for imaging studies in SARS-CoV-2 infected patients - recommendations of the Polish Medical Society of Radiology.
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Cieszanowski A, Czekajska E, Giżycka B, Gruszczyńska K, Oronowicz-Jaśkowiak AS, Podgórska J, Serafin Z, Szurowska E, and Walecki J
- Abstract
The pandemic involving COVID-19 caused by the SARS-CoV-2 coronavirus, due to its severe symptoms and high transmission rate, has gone on to pose a control challenge for healthcare systems all around the world. We present the third version of the recommendations of the Polish Medical Society of Radiology (PMSR), presuming that our knowledge on COVID-19 will advance further rapidly, to the extent that further supplementation and modification will prove necessary. These recommendations involve rules of conduct, procedures, and safety measures that should be introduced in radiology departments, as well as indications for imaging studies., Competing Interests: The authors report no conflict of interest., (© Pol J Radiol 2022.)
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- 2022
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25. The unusual history of stroke due to coagulopathy caused by SARS-CoV-2 infection in a 14-year-old boy with two heart tumors.
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Szydłowski L, Gruszczyńska K, Kusa J, Stanek P, Machnikowska-Sokołowska M, Morka A, Zalewski G, Moric-Janiszewska E, Olczak Z, Pietruszewski J, Paleń P, Poprocka J, and Undas A
- Subjects
- Adolescent, Humans, Male, SARS-CoV-2, COVID-19, Heart Neoplasms, Stroke etiology
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- 2022
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26. Multiple variants of obstructed hemivagina and ipsilateral renal anomaly (OHVIRA) syndrome - one clinical center case series and the systematic review of 734 cases.
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Kudela G, Wiernik A, Drosdzol-Cop A, Machnikowska-Sokołowska M, Gawlik A, Hyla-Klekot L, Gruszczyńska K, and Koszutski T
- Subjects
- Female, Humans, Infant, Kidney surgery, Retrospective Studies, Uterus, Vagina surgery, Abnormalities, Multiple epidemiology, Abnormalities, Multiple surgery, Kidney Diseases epidemiology, Kidney Diseases surgery, Urogenital Abnormalities
- Abstract
Introduction: Obstructed hemivagina and ipsilateral renal anomaly (OHVIRA) syndrome is a rare female urogenital tract malformation., Study Objective: To present 10 patients with OHVIRA treated at the clinical center. To perform a systematic review of OHVIRA case series related to the prevalence of anatomical variants, surgical interventions and endometriosis, and to compare them with our case series., Materials and Methods: Medical records from 10 OHVIRA patients treated between 2016 and 2020 were retrospectively reviewed. For the systematic review, PubMed and Web of Science were used to search for relevant studies. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were strictly followed., Results: The most common anatomical variant includes left obstructed hemivagina (50.7%) with isolated hematocolpos or hydrocolpos (55.9%), uterus didelphys (82.9%), and ipsilateral renal agenesis (92.2%). Vaginal septectomy was the most common surgical approach (86.5%). Hemivaginectomy (2.2%), hemihysterectomy (4.2%), or total hysterectomy (0.7%) were also performed in several patients. Some subjects required salpingectomy (3.3%) or oophorectomy (1.8%). 7.5% of patients, mainly infants, did not require surgery due to the spontaneous resolution of hydrocolpos. Endometriosis was fortuitously found in 13.6% of the selected cases who underwent laparoscopy or laparotomy., Discussion: The most common variant of OHVIRA includes isolated hematocolpos and a thick vaginal septum between adjacent hemivaginas. Endometriosis was present in approximately 14% of OHVIRA patients, but this number is probably underestimated. Routine laparoscopy is not required. However, all patients need further monitoring due to a higher risk of endometriosis. Based on the analyzed studies and our case series, vaginal septectomy is a sufficient surgical technique to relieve symptoms and prevent possible complications in most OHVIRA patients., (Copyright © 2021 Journal of Pediatric Urology Company. Published by Elsevier Ltd. All rights reserved.)
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- 2021
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27. Analysis of the Clinical Course of Primary Sclerosing Cholangitis in Paediatric Population-Single Center Study.
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Wiecek S, Wojtyniak A, Pindur B, Machnikowska-Sokołowska M, Gruszczyńska K, and Grzybowska-Chlebowczyk U
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- Child, Female, Humans, Male, Syndrome, Cholangitis, Sclerosing, Colitis, Ulcerative, Crohn Disease, Inflammatory Bowel Diseases
- Abstract
Background and Objectives: Primary sclerosing cholangitis (PSC) is a rare cholestatic disease of the liver of unknown etiology, severe course and poor prognosis. PSC most often co-occurs with inflammatory bowel diseases (IBD), especially with ulcerative colitis (UC). The aim of the study was the analysis of the clinical course of primary sclerosing cholangitis in children, hospitalized in the Gastroenterology Unit in Katowice. Materials and Methods: The analysis included 30 patients, aged from 7 to 18 years, 21/30 boys (70%) and 9/30 girls (30%), diagnosed with PSC in the years 2009-2019. The analysis included the age at diagnosis, clinical symptoms, course of the disease, coexisting diseases, laboratory and imaging results, and complications. Results: The average age at diagnosis was 13 years. 22/30 (73.3%) patients suffered from UC, 4/30 (13.3%) were diagnosed with Crohn's disease (CD), 2/30 (6.66%) with Eosinophilic Colitis (EC). 2/30 patients (6.66%) had no clinical evidence of coexistent IBD to date. In addition, 7/30 (23.3%) had an overlap syndrome of primary sclerosing cholangitis/autoimmune hepatitis. When PSC was detected before IBD (6/30-20%), patients had complications more often compared to those diagnosed with IBD first or PSC and IBD at the same time. At the moment of diagnosis 6/30 (20%) patients presented with abdominal pain, which was the most common symptom, 3/30 (10%) jaundice, while 17/30 (56.6%) were asymptomatic but had abnormal results of the laboratory tests. Conclusions: Monitoring liver markers in IBD patients is important since most PSC cases are asymptomatic and their elevation might be the first sign of the disease. Patients diagnosed with PSC before IBD diagnosis are more likely to have a more aggressive course of the disease.
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- 2021
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28. Assessment of Post-Stroke Consequences in Pediatric Ischemic Stroke in the Context of Neuroimaging Results-Experience from a Single Medical Center.
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Kopyta I, Sarecka-Hujar B, Raczkiewicz D, Gruszczyńska K, and Machnikowska-Sokołowska M
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Arterial ischemic stroke (AIS) in children is a rare condition; its frequency is estimated at 0.58 to 7.9 new onsets in 100,000 children per year. The knowledge on risk factors, clinical outcomes and consequences of pediatric AIS is increasing. However, there are still many unknowns in the field. The aim of the study was to analyze the clinical presentation of pediatric AIS and its consequences according to the neuroimaging results and location of ischemia. The research was retrospective and observational. The analyzed group consisted of 75 AIS children (32 girls, 43 boys), whereby the age of the patients ranged from 9 months to 18 years at stroke onset. All the patients were diagnosed and treated in one tertiary center. The most frequent stroke subtype was total anterior circulation infarct (TACI) with most common ischemic focus location in temporal lobe and vascular pathology in middle cerebral artery (MCA). The location of ischemic focus in the brain correlated with post-stroke outcomes: intellectual delay and epilepsy, hemiparesis corresponded to the location of vascular pathology. A correlation found between ischemic lesion location and vascular pathology with post-stroke consequences in pediatric AIS may be important information and helpful in choosing proper early therapy. The expected results should lead to lesser severity of late post-stroke outcomes.
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- 2021
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29. Analysis of Point Shear Wave Elastography and Biochemical Markers for the Detection of Liver Fibrosis.
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Cebula M, Gruszczyńska K, Hartleb M, and Baron J
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- Adult, Aged, Biomarkers, Female, Humans, Liver diagnostic imaging, Liver pathology, Liver Cirrhosis diagnostic imaging, Liver Cirrhosis pathology, Male, Middle Aged, Reproducibility of Results, Elasticity Imaging Techniques, Liver Diseases
- Abstract
Background and Objectives: This work focuses on the possibility of using the point shear wave elastography (pSWE) method for detecting biochemical markers in diffuse liver diseases. Additionally, this study addresses the issue of the influence of ultrasound factors on the pSWE quality indicators of the obtained measurements. Materials and Methods: A pSWE examination was performed on 139 patients (69 female and 70 male) diagnosed with diffuse liver disease. The average age for all patients was 50.7 ± 15.0 years (female: 52.7 ± 15.2 years; male: 48.8 ± 14.6 years). Of these 139 patients, 65 met the inclusion criteria regarding biochemical parameters. The pSWE quality indicators were related to abnormalities found in B-mode ultrasound. Results: A strong positive correlation was found between the results of the pSWE and all biochemical indexes analysed, with the exception of age/platelet count (PLT), for which an average correlation was obtained. The greatest correlation was observed between the elastography and King's Score index. There was no correlation observed between elastography and any of the analysed parameters or biochemical indexes considered. The pSWE measurements were impaired by factors such as thick soft tissue, uneven hepatic surface, hepatomegaly and female gender. No statistically significant difference in pSWE quality indicators parameters was found between disease entities. Conclusions: pSWE seems to be a complementary method for detecting biochemical indexes, but its results can be influenced by numerous factors.
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- 2021
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30. Leukoencephalopathy with Calcifications and Cysts-The First Polish Patient with Labrune Syndrome.
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Machnikowska-Sokołowska M, Pilch J, Paprocka J, Rydzanicz M, Pollak A, Kosińska J, Gasperowicz P, Gruszczyńska K, Emich-Widera E, and Płoski R
- Abstract
Leukoencephalopathy with calcifications and cysts (LCC) is a triad of neuroradiological symptoms characteristic of Labrune syndrome, which was first described in 1996. For 20 years, the diagnosis was only based on clinical, neuroradiological and histopathological findings. Differential diagnosis included a wide spectrum of diseases. Finally, in 2016, genetic mutation in the SNORD118 gene was confirmed to cause Labrune syndrome. The authors describe a case of a teenage girl with progressive headaches, without developmental delay, presenting with calcifications and white matter abnormality in neuroimaging. Follow-up studies showed the progression of leukoencephalopathy and cyst formation. The first symptoms and initial imaging results posed diagnostic challenges. The final diagnosis was established based on genetic results. The authors discuss the possible therapy of LCC with Bevacizumab.
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- 2020
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31. Neuroimaging of Basal Ganglia in Neurometabolic Diseases in Children.
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Paprocka J, Machnikowska-Sokołowska M, Gruszczyńska K, and Emich-Widera E
- Abstract
Diseases primarily affecting the basal ganglia in children result in characteristic disturbances of movement and muscle tone. Both experimental and clinical evidence indicates that the basal ganglia also play a role in higher mental states. The basal ganglia can be affected by neurometabolic, degenerative diseases or other conditions from which they must be differentiated. Neuroradiological findings in basal ganglia diseases are also known. However, they may be similar in different diseases. Their assessment in children may require repeated MRI examinations depending on the stage of brain development (mainly the level of myelination). A large spectrum of pathological changes in the basal ganglia in many diseases is caused by their vulnerability to metabolic abnormalities and chemical or ischemic trauma. The diagnosis is usually established by correlation of clinical and radiological findings. Neuroimaging of basal ganglia in neurometabolic diseases is helpful in early diagnosis and monitoring of changes for optimal therapy. This review focuses on neuroimaging of basal ganglia and its role in the differential diagnosis of inborn errors of metabolism.
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- 2020
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32. Hand Injuries in the Polish Silesian Paediatric Population-An Exploratory Cross-Sectional Study of Post-Traumatic X-rays.
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Cebula M, Modlińska S, Machnikowska-Sokołowska M, Komenda J, Cebula A, Baron J, and Gruszczyńska K
- Subjects
- Adolescent, Child, Cross-Sectional Studies, Female, Humans, Male, Poland epidemiology, Retrospective Studies, X-Rays, Finger Phalanges diagnostic imaging, Fractures, Bone diagnostic imaging, Fractures, Bone epidemiology, Fractures, Bone etiology, Hand Injuries diagnostic imaging, Hand Injuries epidemiology, Hand Injuries etiology
- Abstract
Background and objectives: In the paediatric population, hand injuries are one of the most frequent injuries and the second most frequent area of fracture. It is estimated that hand injuries account for up to 23% of the trauma-related causes of emergency department visits. Not only are they a significant factor in health care costs, but they may also lead to detrimental and long-term consequences for the patient. The discrepancy observed between the published studies suggests a geographical variation in their epidemiology. The aim of this study is to determine the localisation of injuries and fractures involving the hand in the paediatric population of the Polish Silesia region. This exploratory cross-sectional study involved 1441 post-traumatic hand X-ray examinations performed at the Department of Diagnostic Imaging of the John Paul II Upper Silesian Child Health Centre in Katowice between January and December 2014. Materials and Methods: The study group consisted of 656 girls and 785 boys who were 11.65 ± 3.50 and 11.51 ± 3.98 years old, respectively (range: 1-18 years). All examinations were evaluated for the location of the injury and presence of fracture(s). Results: Finger injuries were dominant ( n = 1346), with the fifth finger being the most frequently injured ( n = 381). The majority of injuries were observed among children who were 11 years old ( n = 176), with a visible peak in the 11- to 13-year-old group. A total of 625 bone fractures were detected. Fractures of the proximal phalanges ( n = 213) and middle phalanges ( n = 159) were most common, and fifth finger ( n = 189) predominance was again observed. A gender-independent positive correlation was found between patients' age and finger injuries ( p < 0.01) as well as metacarpal injuries ( p < 0.01). There was no correlation between patients' age and fractures in these locations ( p > 0.05). Metacarpal injuries ( p < 0.01), finger injuries ( p < 0.01), fractures ( p = 0.01), and fractures with displacement ( p = 0.03) were more common among males regardless of age. Conclusions: The results indicate that 11-year-old boys are at an increased risk of hand injuries and fractures. The distal and middle phalanges of the right hand, especially of the fifth digit, were the most susceptible to fracture localisation. Thus, injuries in these areas should be perceived as most likely to cause fractures and therefore demand careful examination.
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- 2020
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33. Management of patients with COVID-19 in radiology departments, and indications regarding imaging studies - recommendations of the Polish Medical Society of Radiology.
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Cieszanowski A, Czekajska E, Giżycka B, Gruszczyńska K, Podgórska J, Oronowicz-Jaśkowiak A, Serafin Z, Szurowska E, and Walecki JM
- Abstract
The pandemic involving COVID-19 caused by the SARS-CoV-2 coronavirus, due to its severe symptoms and high transmission rate, has gone on to pose a control challenge for healthcare systems all around the world. We present the second version of the Recommendations of the Polish Medical Society of Radiology, presuming that our knowledge on COVID-19 will advance further rapidly, to the extent that further supplementation and modification will prove necessary. These Recommendations involve rules of conduct, procedures, and safety measures that should be introduced in radiology departments, as well as indications for imaging studies., Competing Interests: The authors report no conflict of interest., (Copyright © Polish Medical Society of Radiology 2020.)
- Published
- 2020
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34. The role of inflammation and potential pharmacological therapy in intracranial aneurysms.
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Gruszka W, Zbroszczyk M, Komenda J, Gruszczyńska K, and Baron J
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- Humans, Inflammation, Prospective Studies, Aneurysm, Ruptured, Embolization, Therapeutic, Intracranial Aneurysm
- Abstract
Intracranial aneurysms remain important clinical concern. There is relatively low risk of rupture of symptomless aneurysms incidentally found in MRA or CTA performed due to other indications. Not all of the intracranial aneurysms should or can be treated with neurosurgery intervention or endovascular embolization. Clinical strategy for small, symptomless, unruptured aneurysms is still questionable. Mechanisms underlying aneurysms formation, progression and rupture are poorly understood. Inflammation is one of the factors suspected to participate in these processes. Therefore the aim of this manuscript is to present current state of knowledge about the role of inflammation in the formation and progression of intracranial aneurysms and in their rupture process. Current knowledge about possible pharmacological treatment of intracranial aneurysms will also be presented. Macrophages infiltration seems to participate in the formation of intracranial aneurysms. Inhibition of signals sent by macrophages may prevent the aneurysms formation. Inflammation present in the wall of the aneurysm seems to be also related to the aneurysm's rupture risk. However it does not seem to be the only cause of the degeneration, but it can be a possible target of drug therapy. Some preliminary studies in humans indicate the potential role of aspirin as a factor that decrease the level of inflammation and lower the risk of rupture of intracranial aneurysms. However further research including a greater number of subjects and a prospective randomized design are necessary to assess the role of aspirin in preventing strategy for small, symptomless, unruptured intracranial aneurysms., (Copyright © 2018 Polish Neurological Society. Published by Elsevier Sp. z o.o. All rights reserved.)
- Published
- 2018
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35. How does nonsyndromic craniosynostosis affect on bone width of nasal cavity in children? - Computed tomography study.
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Gruszczyńska K, Likus W, Onyszczuk M, Wawruszczak R, Gołdyn K, Olczak Z, Machnikowska-Sokołowska M, Mandera M, and Baron J
- Subjects
- Age Factors, Child, Preschool, Craniosynostoses diagnostic imaging, Female, Humans, Infant, Infant, Newborn, Male, Nasal Bone diagnostic imaging, Nasal Cavity diagnostic imaging, Nasal Septum diagnostic imaging, Nasal Septum pathology, Sex Factors, Tomography, X-Ray Computed, Craniosynostoses pathology, Nasal Bone pathology, Nasal Cavity pathology
- Abstract
Craniosynostosis is caused by premature fusion of one or more cranial sutures, restricting skull, brain and face growth. Nonsyndromic craniosynostosis could disturb the proportions of face. Although morphometric diameters of nasal cavity in healthy children are already known, they have not been established yet in children with nonsyndromic craniosynostosis. The aim our study was to check whether diameters of bone structures of nasal cavity in children with nonsyndromic craniosynostosis measured in CT are within normal range. 249 children aged 0-36 months (96 with clinical diagnosis of nonsyndromic craniosynostosis and 153 in control group) were included into the study. The following diameters were measured on head CT scans: anterior bony width (ABW), bony choanal aperture width (BCAW), right and left posterior bony width (between bone sidewall and nasal cavity septum-RPBW and LPBW). The study group has been divided into 4 categories, depending on child's age. The dimensions measured between bone structures of nasal cavity were statistically significantly lower in comparison to the control group. They did not depend on the sex for ABW, nor on age in groups 7-12 months and < 2 years for BCAW, RPBW and LPBW. The measured dimensions increased with age. In children with nonsyndromic craniosynostosis the diameter of pyriform aperture and bony choanal aperture were lower than in controls, what may be described as fronto-orbital anomalies. Morphometric measurements of anthropometric indicators on CT scans could be used as standards in the clinical identification of craniosynostosis type and may help in planning surgical procedures, particularly in the facial skeleton in children., Competing Interests: The authors have declared that no competing interests exist.
- Published
- 2018
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36. PRES in the course of hemato-oncological treatment in children.
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Musioł K, Waz S, Boroń M, Kwiatek M, Machnikowska-Sokołowska M, Gruszczyńska K, and Sobol-Milejska G
- Subjects
- Adolescent, Antineoplastic Agents adverse effects, Blood Pressure physiology, Child, Child, Preschool, Epilepsy diagnostic imaging, Epilepsy etiology, Female, Hepatoblastoma diagnostic imaging, Humans, Image Processing, Computer-Assisted, Leukemia, Lymphoid diagnostic imaging, Magnetic Resonance Imaging, Male, Posterior Leukoencephalopathy Syndrome diagnostic imaging, Retrospective Studies, Risk Factors, Tomography Scanners, X-Ray Computed, Hepatoblastoma drug therapy, Leukemia, Lymphoid drug therapy, Neuroblastoma drug therapy, Posterior Leukoencephalopathy Syndrome etiology
- Abstract
Introduction: Posterior reversible leukoencephalopathy syndrome (PRES) is a clinical syndrome of varying aetiologies, characterised by acute neurological symptoms of brain dysfunction with MRI abnormalities in posterior cerebral white and grey matter. In most cases, symptoms resolve without neurological consequences., Aim: The aim of this paper is the analysis of predisposing factors, clinical outcomes and radiological features of PRES in eight children with hemato-oncological disease., Material and Methods: We analysed the medical records of eight hemato-oncological patients aged from 3.0 to 16.1 years. The mean of age at primary diagnosis was 8.5 years., Results: All patients had both clinical and radiological PRES features. Seven out of eight underwent intensive chemotherapy regimens. Time elapsed from start of treatment to the occurrence of PRES ranged from 6 to 556 days. In one case, PRES occurred before chemotherapy and was the first symptom of cancer. Most (six of eight) patients had history of hypertension (> 95pc) and some (two of eight) occurred electrolyte imbalance-mainly hypomagnesaemia. Patients presented headache (seven of eight), disturbances of consciousness (six of eight), seizures (six of eight), visual changes (four of eight) and vomiting (three of eight). MRI demonstrated abnormalities in seven children: typical cerebral oedema in the white matter of the occipital to the parietal lobes. Most patient lesions in the MRI shrunk after 4 weeks, and clinical symptoms of PRES disappeared completely within a few hours to few days., Conclusion: PRES may complicate oncological treatment in children. Hypertension is the most important risk factor of PRES. PRES should be included in differential diagnosis in all patients with acute neurological symptoms.
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- 2018
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37. Acute pancreatitis in children.
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Grzybowska-Chlebowczyk U, Jasielska M, Flak-Wancerz A, Więcek S, Gruszczyńska K, Chlebowczyk W, and Woś H
- Abstract
Introduction: The acute pancreatitis is a rare disease, but it has started to be diagnosed more often in children., Aim: The aim of the study was single-centre, retrospective analysis of the incidence, aetiology, and clinical course of acute pancreatitis in children., Material and Methods: We analysed the medical records of patients with acute pancreatitis hospitalised in the Gastroenterology Unit of the Paediatrics Department, Medical University of Silesia from Jan 2004 to Dec 2013., Results: There were 76 cases of acute pancreatitis among 51 children (average age: 12.07 years) hospitalised in the Gastroenterology Unit between January 2004 and December 2013. The diagnosis of acute pancreatitis was performed on the basis of INSPIRE criteria and modified Atlanta classification. Patients were divided into groups: I - 1-12 years old, which included 20 (39.21%) children and II - 13-18 years old, with 31 (60.78%) children. The idiopathic aetiology was the most common cause of acute pancreatitis, occurring in 22 (43.1%) children, and in 15 cases the aetiology of the disease was biliary (29.4%). Genetically determined causes were diagnosed in 8 (15.7%) patients, the PRSS1 mutation in four patients, mutation in SPINK1 in 1 child, and CFTR gene mutation in 1 child. Two children simultaneously had two genes mutations ( CFTR , SPINK1 ), and during the considered period had more than one episode of acute pancreatitis., Conclusions: Acute pancreatitis of idiopathic aetiology was most common among the examined children, and this should encourage the continued search for the causes of disease, especially genetic, and with particular emphasis on younger age group.
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- 2018
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38. Neurodegenerative changes detected by neuroimaging in a patient with contiguous X-chromosome deletion syndrome encompassing BTK and TIMM8A genes.
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Szaflarska A, Rutkowska-Zapała M, Gruca A, Szewczyk K, Bik-Multanowski M, Lenart M, Surman M, Kopyta I, Głuszkiewicz E, Machnikowska-Sokołowska M, Gruszczyńska K, Pituch-Noworolska A, and Siedlar M
- Abstract
Introduction: In this study we describe a patient with gross deletion containing the BTK and TIMM8A genes. Mutations in these genes are responsible for X-linked agammaglobulinemia and Mohr-Tranebjaerg syndrome, respectively. X linked agammaglobulinemia is a rare primary immunodeficiency characterized by low levels of B lymphocytes and recurrent microbial infections, whereas, Mohr-Tranebjaerg syndrome is a progressive neurodegenerative disorder with early onset of sensorineural deafness., Material and Methods: For neuroimaging, the magnetic resonance imaging and magnetic resonance spectroscopy of the brain were performed. Microarray analysis was performed to establish the extent of deletion., Results: The first clinical symptoms observed in our patient at the age of 6 months were connected with primary humoral immunodeficiency, whereas clinical signs of MTS emerged in the third year of live. Interestingly, the loss of speech ability was not accompanied by hearing failure. Neuroimaging of the brain suggested leukodystrophy. Molecular tests revealed contiguous X-chromosome deletion syndrome encompassing BTK (from exons 6 through 19) and TIMM8A genes. The loss of the patient's DNA fragment was accurately localized from 100 601 727 to 100 617 576 bp on chromosome's loci Xq22.1., Conclusions: We diagnosed XLA-MTS in the first Polish patient on the basis of particular molecular methods. We detected neurodegenerative changes in MRI and MR spectroscopy in this patient. Our results provide further insight into this rare syndrome., Competing Interests: The authors declare no conflict of interest.
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- 2018
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39. Evaluation of Endovascular Embolization of Cerebral Aneurysms by Hydrogel Coils.
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Knap D, Gruszka W, Sieroń D, Gruszczyńska K, Zawadzki M, Zbroszczyk M, and Baron J
- Abstract
Background: Hydrogel coils were created to improve the chances of an effective endovascular treatment of cerebral aneurysms. Achieving a high packing density of coils in the lumen of aneurysms can decrease the risk of recurrence. The aim of the present study is to report our initial experience on the effectiveness and safety of endovascular treatment of intracranial aneurysms with the use hydrogel coils., Material/methods: Sixty patients (age: 28-72 years) (45 women, 15 men) were treated. In 18 patients (30%), subarachnoid hemorrhage was present. Digital subtraction angiography (DSA) of cerebral vessels with rotational scanning was performed. Image analysis was performed by the Philips Integris 3D RA device,which is a specialized workstation (Three-Dimensional Rotational Angiography). 3D reconstructions of cerebral arteries were created based on the data. Sixty-six cerebral aneurysms were embolized with hydrogel coils, which expand in contact with blood. reaching the maximum diameter in about 20 minutes. In 29 aneurysms (43.9%), the effect of the procedure was confirmed on a follow-up DSA after 8.0±4.1 months from the initial treatment., Results: A complete embolization was performed in 55 aneurysms (83.3%), and partial embolization in 11 aneurysms (16.7%). In 6 aneurysms (9.1%), re-embolization was necessary and it resulted in a complete embolization of 5 aneurysms. On a follow-up DSA, complete embolization was present in 25 aneurysms (86.2%), and partial embolization in 4 aneurysms (13.8%), respectively., Conclusions: Endovascular embolization with hydrogel coils is an effective and safe treatment method for cerebral aneurysms, although it carries the risk of some complications.
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- 2017
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40. Effects of Transendocardial Delivery of Bone Marrow-Derived CD133 + Cells on Left Ventricle Perfusion and Function in Patients With Refractory Angina: Final Results of Randomized, Double-Blinded, Placebo-Controlled REGENT-VSEL Trial.
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Wojakowski W, Jadczyk T, Michalewska-Włudarczyk A, Parma Z, Markiewicz M, Rychlik W, Kostkiewicz M, Gruszczyńska K, Błach A, Dzier Zak-Mietła M, Wańha W, Ciosek J, Ochała B, Rzeszutko Ł, Cybulski W, Partyka Ł, Zasada W, Włudarczyk W, Dworowy S, Kuczmik W, Smolka G, Pawłowski T, Ochała A, and Tendera M
- Subjects
- Aged, Angina Pectoris epidemiology, Bone Marrow Cells physiology, Canada epidemiology, Double-Blind Method, Endocardium cytology, Female, Follow-Up Studies, Humans, Magnetic Resonance Imaging methods, Male, Middle Aged, Prospective Studies, Tomography, Emission-Computed, Single-Photon methods, Transplantation, Autologous methods, Treatment Outcome, AC133 Antigen administration & dosage, Angina Pectoris diagnostic imaging, Angina Pectoris therapy, Bone Marrow Transplantation methods, Endocardium physiology, Ventricular Function, Left physiology
- Abstract
Rationale: New therapies for refractory angina are needed., Objective: Assessment of transendocardial delivery of bone marrow CD133
+ cells in patients with refractory angina., Methods and Results: Randomized, double-blinded, placebo-controlled trial enrolled 31 patients with recurrent Canadian Cardiovascular Society II-IV angina, despite optimal medical therapy, ≥1 myocardial segment with inducible ischemia in Tc-99m SPECT who underwent bone marrow biopsy and were allocated to cells (n=16) or placebo (n=15). Primary end point was absolute change in myocardial ischemia by SPECT. Secondary end points were left ventricular function and volumes by magnetic resonance imaging and angina severity. After 4 months, there were no significant differences in extent of inducible ischemia between groups (summed difference score mean [±SD]: 2.60 [2.6] versus 3.63 [3.6], P =0.52; total perfusion deficit: 3.60 [3.6] versus 5.01 [4.3], P =0.32; absolute changes of summed difference score: -1.38 [5.2] versus -0.73 [1.9], P =0.65; and total perfusion deficit: -1.33 [3.3] versus -2.19 [6.6], P =0.65). There was a significant reduction of left ventricular volumes (end-systolic volume: -4.3 [11.3] versus 7.4 [11.8], P =0.02; end-diastolic volume: -9.1 [14.9] versus 7.4 [15.8], P =0.02) and no significant change of left ventricular ejection fraction in the cell group. There was no difference in number of patients showing improvement of ≥1 Canadian Cardiovascular Society class after 1 (41.7% versus 58.3%; P =0.68), 4 (50% versus 33.3%; P =0.63), 6 (70% versus 50.0%; P =0.42), and 12 months (55.6% versus 81.8%; P =0.33) and use of nitrates after 12 months., Conclusion: Transendocardial CD133+ cell therapy was safe. Study was underpowered to conclusively validate the efficacy, but it did not show a significant reduction of myocardial ischemia and angina versus placebo., Clinical Trial Registration: URL: http://www.clinicaltrials.gov. Unique identifier: NCT01660581., (© 2016 American Heart Association, Inc.)- Published
- 2017
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41. Perihepatic lymphadenopathy in children with chronic viral hepatitis.
- Author
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Gruszczyńska K and Baron J
- Published
- 2015
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42. Auxologic parameters and response to 2-year therapy with recombinant human growth hormone in growth hormone deficient children with an ectopic posterior pituitary.
- Author
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Kalina M, Kalina-Faska B, Gruszczyńska K, Baron J, Cisowska A, Morawiec K, Biel-Lewandowska P, and Małecka-Tendera E
- Subjects
- Adolescent, Child, Child, Preschool, Female, Follow-Up Studies, Human Growth Hormone administration & dosage, Humans, Male, Treatment Outcome, Body Height drug effects, Bone Development drug effects, Dwarfism, Pituitary drug therapy, Human Growth Hormone pharmacology, Pituitary Gland, Posterior pathology
- Abstract
Background: Structural defects of the hypothalamic-pituitary area in MRI are suggested as being a more accurate marker of growth hormone deficiency (GHD) than laboratory assays., Objective: To compare auxological characteristics in GHD children with normal pituitary (NP) function and with ectopic posterior pituitary (EPP), prior to therapy with recombinant human growth hormone (rhGH), extending the follow-up to two years following treatment., Design: Eighty-six (86) GHD patients were divided into two groups depending on the pituitary MRI: the EPP (23 children, 3.2-16.8 years old) and the NP group (63 children, 3.3-14.8 years old). Height deficits in the population (hSD) and parents (hSD-mpSD) and the change of hSD and bone/chronological age ratio were assessed before and after 12 and 24 months of rhGH therapy., Results: Height deficits before treatment were significantly greater in EPP compared to NP [median -4.07 (-7.06, -2.75) vs -3.15 (-4.9, -2.35) for hSD, and -3.65 (-7.06, -1.21) vs -1.83 (-4.31, -0.28) for hSD-mpSD; p<0.05]. Bone age was significantly delayed in the EPP group [0.62 (0.27, 0.92) vs 0.75 (0.21, 0.71); p<0.05]; differences remained significant during follow-up. After 12 months of rhGH therapy, EPP showed significantly greater catch-up growth compared to NP [ΔhSD=1.2 (0.42, 2.69) vs 0.74 (0.05, 1.48); p<0.05]. In the 2nd year, height velocity slowed down and was comparable in the two groups. At the conclusion of the study, hSD was similar in both groups, but hSD-mpSD was more deviated in EPP [-1.79 (-3.71, -1.21) vs -1.1 (0.98, -0.07); p<0.05]., Conclusions: The study showed relevant auxologic differences between EPP and NP children, as well as beneficial effects of rhGH therapy in both groups.
- Published
- 2015
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43. Anomalous origin of the coronary artery from the wrong coronary sinus evaluated with computed tomography: "high-risk" anatomy and its clinical relevance.
- Author
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Krupiński M, Urbańczyk-Zawadzka M, Laskowicz B, Irzyk M, Banyś R, Klimeczek P, Gruszczyńska K, and Baron J
- Subjects
- Chest Pain diagnostic imaging, Chest Pain etiology, Coronary Sinus diagnostic imaging, Coronary Vessel Anomalies complications, Diagnosis, Differential, Female, Humans, Male, Middle Aged, Poland epidemiology, Prevalence, Risk Factors, Chest Pain epidemiology, Coronary Sinus abnormalities, Coronary Vessel Anomalies diagnostic imaging, Multidetector Computed Tomography methods
- Abstract
Objective: The aim of the study was to assess coronary arteries arising from the wrong coronary sinus, including CT-evaluated high-risk anatomic features, clinical symptoms and cardiac events during follow-up., Methods: A total of 7,115 patients scheduled for 64-slice or dual-source cardiac CT were screened for the presence of isolated anomalous origin of the coronary artery from the wrong coronary sinus., Results: Anomalous origin of the coronary artery was found in 54 (0.76 %) patients (29 men, 25 women, mean age 60.9 ± 11.6 years). Sixteen (30 %) patients with abnormal right coronary origin (ARCA) more commonly had a slit-like orifice (15 vs. 3; p < 0.001), intramural course (15 vs. 3; p < 0.001) and interarterial course (11 vs. 0; p < 0.001) than 22 (41 %) and 13 (24 %) individuals with abnormal circumflex artery (ALCx) and left coronary artery (ALCA) origin, respectively. Patients with ALCA presented less frequently with chest pain than subjects with ARCA and ALCx (25 vs. 3; p = 0.03). Patients with ARCA tended to show higher occurrence of cardiac events in the follow-up than individuals with ALCA and ALCx (5 vs. 4; p = NS)., Conclusions: High-risk anatomy features are most common in patients with ARCA and these patients also have higher prevalence of chest pain and cardiac events in the follow-up than individuals with ALCA and ALCx., Key Points: • Multislice computed tomography enables detection and evaluation of the coronary artery anomalies. • Anomalous anatomy of the coronary artery potentially influences the prevalence of adverse events. • Adverse events tend to be most common in anomalous right coronary arteries.
- Published
- 2014
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44. Mechanisms of functional mitral regurgitation in cardiomyopathy secondary to anterior infarction.
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Deja MA, Janusiewicz P, Gruszczyńska K, Biernat J, Baron J, Malinowski M, Gołba KS, and Woś S
- Subjects
- Aged, Cardiac Imaging Techniques, Cardiomyopathies epidemiology, Echocardiography, Female, Heart Ventricles pathology, Heart Ventricles physiopathology, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Mitral Valve pathology, Mitral Valve physiopathology, Mitral Valve Insufficiency epidemiology, Mitral Valve Insufficiency physiopathology, Myocardial Infarction epidemiology, Odds Ratio, Cardiomyopathies etiology, Mitral Valve Insufficiency complications, Myocardial Infarction complications
- Abstract
Objectives: It remains unclear why some patients with cardiomyopathy secondary to anterior infarction do, and others do not develop functional mitral regurgitation (MR)., Methods: Thirty-six patients after anterior infarction with ejection fraction (EF) below 35%, 18 with no/trivial and 18 with moderate/severe MR, underwent cardiac magnetic resonance imaging. Parameters describing the geometry of the mitral valve, subvalvular apparatus and left ventricle were measured., Results: The septolateral and commissure-to-commissure mitral annular diameters were bigger in patients with MR. The odds ratio (OR) of developing regurgitation was 25.0 (95% confidence interval [95% CI] 4.3-144.3; P < 0.001) for end-systolic septolateral mitral annulus diameter above 20 mm/m(2). MR was less likely in patients with straighter posterior papillary muscle (OR 0.040, 95% CI 0.007-0.23; P < 0.001-for the angle between muscle axis and mitral annulus plane >81°), and more likely (OR 7.9, 95% CI 1.6-39.4; P = 0.008) with posterior papillary muscle tethering >23 mm/m(2). Regurgitation was less likely (OR 0.032, 95% CI 0.003-0.33; P = 0.001) with anterolateral papillary muscle tip to ipsilateral mitral annulus distance in end-diastole longer than 13 mm/m(2). Left ventricular EF, volumes and the overall end-systolic and end-diastolic wall thicknesses did not differ between the groups. Patients with MR had thinner myocardium proximal to the base of the anterior and distal to the base of the posterior papillary muscle., Conclusions: Inferior extension of anterior infarction and more leaning posterior papillary muscle are the major components resulting in the development of ischaemic MR in patients with cardiomyopathy secondary to anterior infarction. Shorter chordae tendineae may constitute the anatomical background that makes the development of ischaemic MR more likely., (© The Author 2014. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.)
- Published
- 2014
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45. Cephalic index in the first three years of life: study of children with normal brain development based on computed tomography.
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Likus W, Bajor G, Gruszczyńska K, Baron J, Markowski J, Machnikowska-Sokołowska M, Milka D, and Lepich T
- Subjects
- Child, Preschool, Female, Humans, Infant, Male, Reference Values, Skull anatomy & histology, Tomography, X-Ray Computed, White People, Brain growth & development, Head anatomy & histology
- Abstract
Cephalic index is a highly useful method for planning surgical procedures, as well as assessing their effectiveness in correcting cranial deformations in children. There are relatively very few studies measuring cephalic index in healthy Caucasian young children. The aim of our study was to develop a classification of current cephalic index for healthy Caucasian children up to 3 years of age with normal brain development, using axial slice computer tomography performed with very thin slices (0.5 mm) resulting in more accurate measurements. 180 healthy infants (83 females and 97 males) were divided into 5 age categories: 0-3, 4-6, 7-12, 13-24, and 25-36 months. The average value of cephalic index in children up to 3 years of age amounted to 81.45 ± 7.06. The index value in case of children under 3 months was 80.19, 4 to 6 months was 81.45, 7 to 12 months was 83.15, in children under 2 years was 81.05, and in children under 3 years was 79.76. Mesocephaly is the dominating skull shape in children. In this study, we formulated a classification of current cephalic indices of children with normal brain development. Our date appears to be of utmost importance in anthropology, anatomy forensic medicine, and genetics.
- Published
- 2014
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46. Nasal region dimensions in children: a CT study and clinical implications.
- Author
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Likus W, Bajor G, Gruszczyńska K, Baron J, and Markowski J
- Subjects
- Child, Preschool, Female, Humans, Infant, Infant, Newborn, Male, Retrospective Studies, Child Development, Nasal Bone diagnostic imaging, Nasal Bone growth & development, Nasal Cavity diagnostic imaging, Nasal Cavity growth & development, Tomography, X-Ray Computed
- Abstract
Atresias of nasal cavity, especially in young children, pose an essential problem in children's otolaryngology. Only a few morphometric studies of nasal cavity concerning healthy neonates and young infants without nasal stenosis are available. Multislice computed tomography is a perfect tool enabling a precise evaluation of anatomic structures. The aim of this study was a complex morphometric evaluation of clinically important bone and mucosal structures of nasal cavity and examination of their dependence on age and sex in children up to 3 years of age. 180 children, age range 0-3 years, were divided into 5 age groups, and measurements of 18 distances between skeletal structures and between mucosal structures of nasal cavity were performed on their CT scans. A correlation between the widths of selected bone structures was examined. There were no statistically significant differences in analyzed morphometric parameters between adjacent age groups. The differences were statistically significant only between extreme age groups. There was a correlation between evaluated structures and age. Our results are a valuable supplement of nasal cavity morphometric data of young children. They may be useful in setting reference values of evaluated parameters in children and in diagnosis and planning of surgical treatment in children's otolaryngology.
- Published
- 2014
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47. [Arrhythmogenic right ventricular cardiomyopathy in contemporary imaging. Expert consensus statement of the Polish Clinical Forum for Cardiovascular Imaging].
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Mizia-Stec K, Wita K, Gruszczyńska K, Wybraniec MT, Biernacka EK, Małek LA, Szyszka A, Kasprzak JD, Płońska-Gościniak E, and Szumowski L
- Subjects
- Humans, Poland, Arrhythmogenic Right Ventricular Dysplasia diagnosis, Diagnostic Imaging methods, Diagnostic Imaging standards
- Published
- 2014
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48. Results of endovascular treatment of aneurysms depending on their size, volume and coil packing density.
- Author
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Knap D, Gruszczyńska K, Partyka R, Ptak D, Korzekwa M, Zbroszczyk M, and Baron J
- Subjects
- Aged, Female, Follow-Up Studies, Humans, Male, Middle Aged, Radiographic Image Interpretation, Computer-Assisted methods, Treatment Outcome, Angiography, Digital Subtraction methods, Coated Materials, Biocompatible metabolism, Embolization, Therapeutic methods, Endovascular Procedures methods, Intracranial Aneurysm physiopathology, Intracranial Aneurysm therapy
- Abstract
Background and Purpose: In contrast to neurosurgery, which is more efficient, endovascular treatment (EVT) is less invasive. The main purpose of EVT is complete occlusion of the aneurysm and protection from subarachnoid haemorrhage. Accurate measurements of the aneurysm (size, volume) obtained using a 3D digital subtraction angiography (DSA) workstation can assist in the proper assessment of coil packing density (CPD), which affects possible distant recanalization. The main disadvantage of endovascular treatment of intracranial aneurysms compared to neurosurgery is the high recurrence rate. We evaluated the results of endovascular treatment of aneurysms depending on their size, volume and coil packing density., Material and Methods: Thirty-five patients with intracranial aneurysms underwent endovascular embolization with bare platinum coils. Three-dimensional DSA was used to evaluate aneurysms' morphology. Eighteen patients underwent 3D DSA follow-up 6-45 months after treatment. Initial and follow-up results of embolization were assessed with the Raymond-Montreal scale. The impact of aneurysms' morphology, volume and initial CPD on endovascular treatment was evaluated., Results: Among 35 patients, complete initial embolization was achieved in 74%. Mean initial aneurysm volume in 3D DSA was 0.517 mL and decreased significantly after embolization. Initial CPD varied from 74% to 2% depending on aneurysm diameter (12.1% for aneurysms ≥ 10 mm, 22.5% for aneurysms < 10 mm). Results of embolization on the Raymond-Montreal scale significantly depended on aneurysms' CPD. Aneurysms' recanalization rate on 3D DSA follow-up was 36%, with complete recanalization in 3.3%., Conclusions: We can achieve a better outcome if size and volume of the aneurysm sac is smaller and if CPD is higher.
- Published
- 2013
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49. Intervertebral disc calcification in children: Case description and review of relevant literature.
- Author
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Sieroń D, Gruszczyńska K, Machnikowska-Sokołowska M, Olczak Z, Knap D, and Baron J
- Abstract
Background: Intervertebral disc calcification is a rare condition in children; in most cases, it is asymptomatic and therefore not diagnosed., Case Reports: In our study, we present a case of idiopathic intervertebral disc calcification within the cervical segment, at the level of C2/C3 and C4/C5 vertebrae in a 5-year-old girl with torticollis. Basic neurological examination supplemented by X-ray examination was performed, showing calcification within the cervical segment at the level of C2/C3 and C4/C5 vertebrae., Conclusions: In order to complement the diagnostics, a CT scan of the cervical spine was performed; the scan confirmed the diagnosis and revealed additional calcification of the anterior longitudinal ligament at the level of C4/C5 vertebrae.
- Published
- 2013
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50. Statistical agreement of left ventricle measurements using cardiac magnetic resonance and 2D echocardiography in ischemic heart failure.
- Author
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Gruszczyńska K, Krzych LJ, Gołba KS, Biernat J, Roleder T, Deja MA, Ulbrych P, Malinowski M, Janusiewicz P, Woś S, and Baron J
- Subjects
- Aged, Female, Heart Ventricles diagnostic imaging, Humans, Male, Middle Aged, Myocardial Ischemia diagnostic imaging, Echocardiography methods, Heart Ventricles pathology, Magnetic Resonance Imaging methods, Myocardial Ischemia pathology
- Abstract
Background: The aim of this study was to compare cardiac magnetic resonance imaging (CMR) with 2-dimensional echocardiography (2D echo) in the assessment of left ventricle (LV) function parameters and mass in patients with ischemic heart disease and severely depressed LV function. Although 2D echo is commonly used to assess LV indices, CMR is the state-of-the-art technique. Agreement between these 2 methods in these patients has not been well established., Material/methods: LV indexed end systolic and diastolic volumes (EDVi and ESVi), indexed mass (LVMi) and ejection fraction (EF) were assessed in 67 patients (12 women), using 2D echo and CMR., Results: According to statistical analysis (Bland-Altman), 2D echo underestimated LV EDV and ESV and overestimated EF and LVMi compared to CMR. The highest correlation between 2D echo and CMR was found for EDVi (R2=0.73, p<0.0001) and ESVi (R2=0.69, p<0.0001) and the lowest for EF (R2=0.21, p=0.001) and LVMi (R2=0.20, p=0.002). The maximal differences between 2D echo and CMR were found for highest mesurements of LV volumes and mass, and for lowest EF values., Conclusions: There is moderate to strong correlation between CMR and 2D echo in the assessment of LV function parameters and mass in patients with ischemic heart failure. Between-method agreement depends on the degree of LV dysfunction. The results of assessment of the severely damaged LV obtained by the use of 2D echo should be interpreted with caution.
- Published
- 2012
- Full Text
- View/download PDF
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