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1. [Intraamnial application of 14C-labeled lecithine at man 13 hrs. ante partum (author's transl)].

Author

Grosspietzsh R, Klink F, von Klitzing L, Endell W, and Oberheuser F

Subjects
Adult, Amnion, Carbon Radioisotopes, Female, Fetus metabolism, Humans, Infant, Newborn, Injections, Intestines analysis, Liver analysis, Lung analysis, Phosphatidylcholines metabolism, Pregnancy, Time Factors, Phosphatidylcholines therapeutic use, Respiratory Distress Syndrome, Newborn prevention & control
Abstract

It was examined, whether by intraamnial applicated lecithine an approaching respiratory distress syndrome could be prevented. This possibility of therapy was tested on a fetus unviable of life. It was shown by examining the lavage-fluid of the fetal lung, as well as the organ homogenates of lung; liver and gut, that the intraamnial applicated lecithine was metabolised and resynthesised in the organism. In the lung the lecithine was present as a complete molecule.

Published
1977

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