6 results on '"Groppo, Marzia"'
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2. Changing trends in acute upper-GI bleeding: a population-based study
- Author
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Loperfido, Silvano, Baldo, Vincenzo, Piovesana, Elena, Bellina, Ludovica, Rossi, Katia, Groppo, Marzia, Caroli, Alessandro, Bò, Nadia Dal, Monica, Fabio, Fabris, Luca, Salvat, Helena Heras, Bassi, Nicolò, and Okolicsanyi, Lajos
- Published
- 2009
- Full Text
- View/download PDF
3. Randomised clinical trial: mucosal protection combined with acid suppression in the treatment of non-erosive reflux disease - efficacy of Esoxx, a hyaluronic acid-chondroitin sulphate based bioadhesive formulation
- Author
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Savarino, V., Pace, F., Scarpignato, C., Astegiano, Marco, Calabrese, Carlo, Cicala, Michele, Ciliberto, Enrico, Conigliaro, Rita, Costamagna, Guido, Cuomo, Rosario, Di Leo, Alfredo, Di Simone, Massimo Pierluigi, Esposito, Pasquale, Groppo, Marzia, Marchi, Santino, Neri, Matteo, Pace, Fabio, Savarino, Vincenzo, Segato, Sergio, Savarino, Vincenzo, Pace, Fabio, Astegiano, M, Calabrese, C, Cicala, M, Ciliberto, E, Conigliaro, R, Costamagna, G, Cuomo, Rosario, Di Leo, A, Di Simone, Mp, Esposito, P, Groppo, M, Marchi, S, Neri, M, Segato, S, Scarpignato, Carmelo, Savarino, V., Pace, F., Scarpignato, C., Astegiano, Marco, Calabrese, Carlo, Cicala, Michele, Ciliberto, Enrico, Conigliaro, Rita, Costamagna, Guido, Di Leo, Alfredo, DI SIMONE, MASSIMO PIERLUIGI, Esposito, Pasquale, Groppo, Marzia, Marchi, Santino, Neri, Matteo, and Segato, Sergio
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Adult ,Male ,medicine.medical_specialty ,Proton Pump Inhibitor ,Chondroitin Sulfates ,Double-Blind Method ,Female ,Gastroesophageal Reflux ,Heartburn ,Humans ,Hyaluronic Acid ,Italy ,Middle Aged ,Proton Pump Inhibitors ,Quality of Life ,Surveys and Questionnaires ,Treatment Outcome ,Nerd ,Randomised Clinical Trial ,Placebo ,Gastroenterology ,law.invention ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,Randomized controlled trial ,law ,Internal medicine ,Hyaluronic acid ,Clinical endpoint ,medicine ,Surveys and Questionnaire ,Pharmacology (medical) ,Hepatology ,business.industry ,Reflux ,Chondroitin Sulfate ,Surgery ,Clinical trial ,chemistry ,030220 oncology & carcinogenesis ,030211 gastroenterology & hepatology ,medicine.symptom ,business ,Human - Abstract
SummaryBackground Several studies have shown that patients with non-erosive reflux disease (NERD) are less responsive to proton pump inhibitors (PPIs) than those with erosive disease as they belong to different subgroups, in whom factors other than acid can trigger symptoms. Aim To evaluate whether combined therapy (mucosal protection plus acid suppression) would improve symptom relief compared to PPI treatment alone. Methods In a multicenter, randomised, double-blind trial, 154 patients with NERD were randomised to receive Esoxx (Alfa Wassermann, Bologna, Italy), a hyaluronic acid-chondroitin sulphate based bioadhesive formulation, or placebo, in addition to acid suppression with standard dose PPIs for 2 weeks. Symptoms (heartburn, acid regurgitation, retrosternal pain and acid taste in the mouth) and health-related quality of life (HRQL) were evaluated before and after treatment. The primary endpoint was the proportion of patients with at least a 3-point reduction in the total symptom score. Results At the end of treatment, the primary endpoint was reached by 52.6% of patients taking Esoxx compared to 32.1% of those given placebo (P < 0.01). The same was true also for HRQL, evaluated by means of the Short Form-36 questionnaire, which improved with both treatments, but some items were significantly better after Esoxx plus PPI therapy. Conclusion The synergistic effect of Essox with PPI treatment suggests that mucosal protection added to acid suppression could improve symptoms and HRQL in NERD patients.
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- 2017
4. Bloating is associated with worse quality of life, treatment satisfaction, and treatment responsiveness among patients with constipation-predominant irritable bowel syndrome and functional constipation
- Author
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Neri, L., Iovino, P., Altomare, Donato Francesco, Annese, Vito, Badiali, Danilo, Basilisco, Guido, Bassotti, Gabrio, Battaglia, Edda, Bazzocchi, Gabriele, Bellini, Massimo, Bendia, Emanuele, Benini, Luigi, Biscaglia, Giuseppe, Biviano, Ivano, Bocchini, Renato, Bonventre, Sebastiano, Bossa, Fabrizio, Brandimarte, Giovanni, Cannizzaro, Renato, Cicala, Michele, Cipolletta, Livio, Clara, Virgilio, Cogliandro, Rosanna, Comandini, Giulia, Corazziari, Enrico, Crotta, Sergio, Cuomo, Rosario, D'Alba, Lucia, De Giorgi, Francesco, Del Piano, Mario, Di Fonzo, Michela, Di Mario, Francesco, Di Stefano, Michele, D'Onofrio, Vittorio, Efthymakis, Kostantinos, Fiore, Pierluigi, Fortuna, Manuela, Fries, Walter, Gaetani, Eleonora, Galeazzi, Francesca, Gasbarrini, Antonio, Geccherle, Andrea, Giangregorio, Francesco, Girardi, Lisa, Grassini, Mario, Groppo, Marzia, Guarnieri, Giovanni, Lo Cascio, Massimiliano, Lolli, Roberto, Luzza, Francesco, Macarri, Giampiero, Marino, Maria, Miraglia, Stefania, Monastra, Santo, Neri, Maria Cristina, Neri, Matteo, Noris, Roberto Antonio, Orselli, Silvia, Passaretti, Sandro, Paviotti, Alberto, Pazzi, Paolo, Pilotto, Alberto, Portincasa, Piero, Ranaldo, Nunzio, Ravelli, Paolo, Rogai, Francesca, Sablich, Renato, Savarino, Vincenzo, Spinzi, Giancarlo, Stanghellini, Vincenzo, Tammaro, Leonardo, Torresan, Francesco, Usai Satta, Paolo, Valle, C. Claudio, Neri, L., Iovino, P., Altomare, Donato Francesco, Annese, Vito, Badiali, Danilo, Basilisco, Guido, Bassotti, Gabrio, Battaglia, Edda, Bazzocchi, Gabriele, Bellini, Massimo, Bendia, Emanuele, Benini, Luigi, Biscaglia, Giuseppe, Biviano, Ivano, Bocchini, Renato, Bonventre, Sebastiano, Bossa, Fabrizio, Brandimarte, Giovanni, Cannizzaro, Renato, Cicala, Michele, Cipolletta, Livio, Clara, Virgilio, Cogliandro, Rosanna, Comandini, Giulia, Corazziari, Enrico, Crotta, Sergio, Cuomo, Rosario, D'Alba, Lucia, De Giorgi, Francesco, Del Piano, Mario, Di Fonzo, Michela, Di Mario, Francesco, Di Stefano, Michele, D'Onofrio, Vittorio, Efthymakis, Kostantino, Fiore, Pierluigi, Fortuna, Manuela, Fries, Walter, Gaetani, Eleonora, Galeazzi, Francesca, Gasbarrini, Antonio, Geccherle, Andrea, Giangregorio, Francesco, Girardi, Lisa, Grassini, Mario, Groppo, Marzia, Guarnieri, Giovanni, Lo Cascio, Massimiliano, Lolli, Roberto, Luzza, Francesco, Macarri, Giampiero, Marino, Maria, Miraglia, Stefania, Monastra, Santo, Neri, Maria Cristina, Neri, Matteo, Noris, Roberto Antonio, Orselli, Silvia, Passaretti, Sandro, Paviotti, Alberto, Pazzi, Paolo, Pilotto, Alberto, Portincasa, Piero, Ranaldo, Nunzio, Ravelli, Paolo, Rogai, Francesca, Sablich, Renato, Savarino, Vincenzo, Spinzi, Giancarlo, Stanghellini, Vincenzo, Tammaro, Leonardo, Torresan, Francesco, Usai Satta, Paolo, Valle, C. Claudio, Altomare, D., Annese, V., Badiali, D., Basilisco, G., Bassotti, G., Battaglia, E., Bazzocchi, G., Bellini, M., Bendia, E., Benini, L., Biscaglia, G., Biviano, I., Bocchini, R., Bonventre, S., Bossa, F., Brandimarte, G., Cannizzaro, R., Cicala, M., Cipolletta, L., Clara, V., Cogliandro, R., Comandini, G., Corazziari, E., Crotta, S., Cuomo, R., D'Alba, L., De Giorgi, F., Del Piano, M., Di Fonzo, M., Di Mario, F., Di Stefano, M., D'Onofrio, V., Efthymakis, K., Fiore, P., Fortuna, M., Fries, W., Gaetani, E., Galeazzi, F., Gasbarrini, A., Geccherle, A., Giangregorio, F., Girardi, L., Grassini, M., Groppo, M., Guarnieri, G., Lo Cascio, M., Lolli, R., Luzza, F., Macarri, G., Marino, M., Miraglia, S., Monastra, S., Neri, M., Noris, R., Orselli, S., Passaretti, S., Paviotti, A., Pazzi, P., Pilotto, A., Portincasa, P., Ranaldo, N., Ravelli, P., Rogai, F., Sablich, R., Savarino, V., Spinzi, G., Stanghellini, V., Tammaro, L., Torresan, F., Usai Satta, P., and Valle, C.
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Adult ,Male ,Quality of life ,medicine.medical_specialty ,Constipation ,Cross-sectional study ,Physiology ,Bloating ,Chronic constipation ,Functional constipation ,Irritable bowel syndrome ,Patient-reported outcomes ,Treatment satisfaction ,Endocrine and Autonomic Systems ,Gastroenterology ,Cross-Sectional Studies ,Female ,Flatulence ,Humans ,Irritable Bowel Syndrome ,Middle Aged ,Prevalence ,Quality of Life ,Surveys and Questionnaires ,Endocrine and Autonomic System ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,medicine ,Patient-reported outcome ,Settore MED/12 - Gastroenterologia ,business.industry ,Settore MED/09 - MEDICINA INTERNA ,medicine.disease ,Settore MED/18 - Chirurgia Generale ,Tolerability ,030220 oncology & carcinogenesis ,Physical therapy ,030211 gastroenterology & hepatology ,medicine.symptom ,business - Abstract
Background The management of bloating is unclear and its relationship with patients' well-being and treatment satisfaction independent of other abdominal symptoms is uncharacterized. We evaluated the association of bloating with patient-reported outcomes. Methods Thirty-nine centers for functional gastrointestinal disorders joined the laxative inadequate relief survey. We enrolled 2203 consecutive outpatients with functional constipation (FC) or constipation-predominant irritable bowel syndrome (IBS-C) in two cross-sectional waves. Both wave 1 and 2 included the SF-12, the patient assessment of constipation-symptoms (PAC-SYM), and the treatment satisfaction questionnaire for medication (TSQM-2). Wave 2 only included a global rating of change (GRC) scale to assess patients' assessment of efficacy concerning treatment switches occurred in the 3 months prior to the interview. Bloating in the abdomen was defined on the basis of PAC-SYM item 3. Key Results The average age was 50.1 years (SD, 16.7) and 82.1% of patients were women. The prevalence of bloating was 91.6% (n = 1970). Bloating was associated with SF-12 Physical Composite Score (p < 0.01), SF-12 Mental Composite Score (p < 0.01), GRC (p < 0.01), Satisfaction with treatment effectiveness (p < 0.01), convenience of administration (p < 0.01), and side effects (p < 0.01) after adjustment for possible confounders. Conclusions & Inferences Our data suggest that patients regard bloating as a key element in assessing clinical changes and treatments' efficacy as this symptom exerts a strong influence on patient-reported outcomes independent of possible confounders and other symptoms of constipation. Our data provide the rationale to investigate the efficacy and tolerability of new treatments specifically addressing this important, yet disregarded, patients' complain.
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- 2016
5. Decline of Incidence and Mortality of Peptic Ulcer Bleeding Between 1983-85 and 2002-04: A Population-Based Study in the Treviso Area (North-East Italy)
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Loperfido, Silvano, primary, Baldo, Vincenzo, additional, Piovesana, Elena, additional, Bellina, Ludovica, additional, Rossi, Katia, additional, Groppo, Marzia, additional, Realdon, Stefano, additional, Caroli, Alessandro, additional, Dal Bò, Nadia, additional, Monica, Fabio, additional, Fabris, Luca, additional, Heras Salvat, Helena, additional, Bassi, Nicolò, additional, and Okolicsanyi, Lajos, additional
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- 2008
- Full Text
- View/download PDF
6. Impact of Multimodal Endoscopic Therapy on Outcome of Acute Upper Gastrointestinal Bleeding (AUGIB): Comparison Between 2002 and 1983-85 in the Treviso Area (North-East Italy)
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Loperfido, Silvano, primary, Bellina, Ludovica, additional, Bo, Nadia Dal, additional, Bizzotto, Sira, additional, Piovesana, Elena, additional, Caroli, Alessandro, additional, Salvat, Helena Heras, additional, Maifreni, Luisa, additional, Monica, Fabio, additional, Salvador, Adelina, additional, Groppo, Marzia, additional, and Okolicsanyi, Lajos, additional
- Published
- 2004
- Full Text
- View/download PDF
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