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2. Genome-wide association analyses of symptom severity among clozapine-treated patients with schizophrenia spectrum disorders

Author

Okhuijsen-Pfeifer, C., van der Horst, M. Z., Bousman, C. A., Lin, B., van Eijk, K. R., Ripke, S., Ayhan, Y., Babaoglu, M. O., Bak, M., Alink, W., van Beek, H., Beld, E., Bouhuis, A., Edlinger, M., Erdogan, I. M., Ertuğrul, A., Yoca, G., Everall, I. P., Görlitz, T., Grootens, K. P., Gutwinski, S., Hallikainen, T., Jeger-Land, E., de Koning, M., Lähteenvuo, M., Legge, S. E., Leucht, S., Morgenroth, C., Müderrisoğlu, A., Narang, A., Pantelis, C., Pardiñas, A. F., Oviedo-Salcedo, T., Schneider-Thoma, J., Schreiter, S., Repo-Tiihonen, E., Tuppurainen, H., Veereschild, M., Veerman, S., de Vos, M., Wagner, E., Cohen, D., Bogers, J. P. A. M., Walters, J. T. R., Yağcıoğlu, A. E. Anil, Tiihonen, J., Hasan, A., and Luykx, J. J.

Published
2022
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3. To continue or not to continue? Antipsychotic medication maintenance versus dose-reduction/discontinuation in first episode psychosis: HAMLETT, a pragmatic multicenter single-blind randomized controlled trial

Author

Begemann, Marieke J. H., Thompson, Ilse A., Veling, Wim, Gangadin, Shiral S., Geraets, Chris N. W., van ‘t Hag, Erna, Müller-Kuperus, Sanne J., Oomen, Priscilla P., Voppel, Alban E., van der Gaag, Mark, Kikkert, Martijn J., Van Os, Jim, Smit, H. Filip E., Knegtering, Rikus H., Wiersma, Sybren, Stouten, Luyken H., Gijsman, Harm J., Wunderink, Lex, Staring, Anton B. P., Veerman, Selene R. T., Mahabir, Amrita G. S., Kurkamp, Jörg, Pijnenborg, Gerdina H. M., Veen, Natalie D., Marcelis, Machteld, Grootens, Koen P., Faber, Gunnar, van Beveren, Nico J., Been, Agaath, van den Brink, Truus, Bak, Maarten, van Amelsvoort, Therese A. M. J., Ruissen, Andrea, Blanke, Christine, Groen, Karin, de Haan, Lieuwe, and Sommer, Iris E. C.

Published
2020
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10. Capillary blood sampling for the determination of clozapine concentrations: analytical validation and patient experience

Author

Breken, Bianca D., Grootens, Koen P., Vermeulen Windsant – van den Tweel, Annemieke M., Hermens, Walter A., and Derijks, Hieronymus J.

Abstract

Patients may be reluctant to start clozapine (CLZ) because of the frequent blood sampling needed for white blood cell monitoring, but also therapeutic drug monitoring of CLZ. Finger prick, instead of venepuncture, might lower the threshold to CLZ use. The aim of this study was to determine whether CLZ concentrations are the same in capillary and venous blood samples. Capillary blood was drawn by finger prick and collected in the Hem-Col tube. Paired capillary and venous blood samples were collected from inpatients and outpatients of a mental health institute. Patients were asked to rate pain, experience, and preference for blood sampling method. Passing-Bablok analysis of 40 paired samples showed that CLZ concentrations were statistically equal in capillary and venous samples {slope 0.96 [95% confidence interval (CI): 0.88–1.04], intercept −6.86 (95% CI: −30.75 to 24.13)}. Venepuncture was the preferred method based on the experience (P = 0.009) and preference (P = 0.043) items. In conclusion, CLZ concentrations were similar in venous and capillary blood samples. Venepuncture appeared to be preferred to finger prick for blood sampling. Our results emphasize the importance of consulting patients’ individual preference for blood sampling method.

Published
2024
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18. Single-cell transcriptomics reveals the identity and regulators of human mast cell progenitors

Author

Wu, Chenyan, Boey, Daryl, Bril, Oscar, Grootens, Jennine, Vijayabaskar, M. S., Sorini, Chiara, Ekoff, Maria, Wilson, Nicola K., Ungerstedt, Johanna S., Nilsson, Gunnar, and Dahlin, Joakim S.

Abstract

Mast cell accumulation is a hallmark of a number of diseases, including allergic asthma and systemic mastocytosis. Immunoglobulin E–mediated crosslinking of the FcεRI receptors causes mast cell activation and contributes to disease pathogenesis. The mast cell lineage is one of the least studied among the hematopoietic cell lineages, and controversies remain about whether FcεRI expression appears during the mast cell progenitor stage or during terminal mast cell maturation. Here, we used single-cell transcriptomics analysis to reveal a temporal association between the appearance of FcεRI and the mast cell gene signature in CD34+ hematopoietic progenitors in adult peripheral blood. In agreement with these data, the FcεRI+ hematopoietic progenitors formed morphologically, phenotypically, and functionally mature mast cells in long-term culture assays. Single-cell transcriptomics analysis further revealed the expression patterns of prospective cytokine receptors regulating development of mast cell progenitors. Culture assays showed that interleukin-3 (IL-3) and IL-5 promoted disparate effects on progenitor cell proliferation and survival, respectively, whereas IL-33 caused robust FcεRI downregulation. Taken together, we showed that FcεRI expression appears at the progenitor stage of mast cell differentiation in peripheral blood. We also showed that external stimuli regulate FcεRI expression of mast cell progenitors, providing a possible explanation for the variable FcεRI expression levels during mast cell development.

Published
2022
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19. Barriers and facilitators for systematically registering adverse drug reactions in electronic health records: a qualitative study with Dutch healthcare professionals

Author

Geeven, Isa P. A. C., Jessurun, Naomi T., Wasylewicz, Arthur T. M., Drent, Marjolein, Spuls, Phyllis I., Hoentjen, Frank, van Puijenbroek, Eugène P., Vonkeman, Harald E., Grootens, Koen P., van Doorn, Martijn B. A., van Den Bemt, Bart J. F., and Bekker, Charlotte L.

Abstract

ABSTRACTBackgroundSystematically registering ADRs in electronic health records (EHRs) likely contribute to patient safety as it enables the exchange of drug safety data. Currently, ADRs registrations by healthcare professionals (HCPs) is suboptimal. This study aimed to identify barriers and facilitators perceived by HCPs to register ADRs systematically in EHRs.Research Design and MethodsA qualitative study with individual interviews was conducted among specialist physicians and hospital pharmacists from 10 different Dutch hospitals. A semi-structured interview guide was used to identify experienced barriers and facilitators for systematically registering ADRs. Data was analyzed following thematic analysis. Themes within barriers and facilitators were aligned with the Capability–Opportunity-Motivation–Behavior (COM-B) framework.ResultsIn total, 16 HCPs were interviewed. Identified barriers were: lack of knowledge to recognize ADRs, time constraints, inadequate IT system, lack of support, stuck in routine, and not recognizing the importance of registering ADRs. Identified facilitators were: enhanced knowledge and awareness of ADRs, functional IT systems, expanding accountability for registration, and motivation toward registering.ConclusionsBarriers and facilitators for registering spanned all aspects of the COM-B model and occurred in individual, social and environmental domains. Addressing these aspects could improve the registration of ADRs and may contribute to patient safety.

Published
2022
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21. Toeleiding naar en voltooiing van leefstijlinterventies voor kinderen met overgewicht en obesitas

Author

Grootens, P., van den Eynde, Emma, Halberstadt, J., Niemer, S.I.J., Seidell, J.C., and Dedding, C.W.M.

Abstract

In het onderzoek ‘Toeleiding naar en voltooiing van leefstijlinterventies voor kinderen met overgewicht en obesitas’ blijkt dat succesvolle toeleiding en voltooiing van leefstijlinterventies niet een kwestie is van de aan- of afwezigheid van één bepaalde factor, maar dat het succesvol starten en afronden van een interventie pas plaatsvindt wanneer de relevante factoren overwegend faciliterend zijn en/of opwegen tegen de belemmerende factoren. Het is uiteindelijk de positieve balans tussen de ervaren barrières en de faciliterende factoren die ervoor zorgt dat mensen een programma voltooien. Barrières zijn onderdeel van het uitdagende leven van deze gezinnen en niet eenvoudig oplosbaar. De kunst is om de barrières daar waar mogelijk te verkleinen én de faciliterende factoren te versterken. Dit onderzoek, wat uitgevoerd is in opdracht van de Amsterdamse Aanpak Gezond Gewicht, levert daartoe belangrijke handvatten

Published
2018

22. Targeted Informed consent : empowering young participants in medical-scientific research

Author

Grootens, P., Broek, J.M. van den, Vries, M.C. de, Dedding, C.W.M., Kalverboer, M.E., Smeets, I., Spaink, H., Molder, H.F.M. te, Rossum, A.M.C. van, Vliet, I.M. van, and Leiden University

Subjects
Participatory research, Health communication, Empowerment, Informed consent, Adolescents, Children, Decision-making
Abstract

Increasingly, pleas are made for extending the involvement of minors in decision-making about participation in pediatric research. However, a number of issues arise from this desired participation of minors. First, involvement in decision-making requires children and adolescents to be adequately informed about what participation in research entails. Second, the plea for increased involvement in decision-making requires further investigation whether children indeed can, should and want to play a role in the decision about research participation. This thesis addresses these issues and thereby contributes to insights in how to empower minors in the context of informed consent for research participation. New informed consent material was developed in close cooperation with children and other end-users, the process of which is described and evaluated. Also, insights in the role that minors can, should and want to play in the informed consent procedure are described. These insights were obtained by reviewing multidisciplinary scientific evidence on the competence of minors, by an ethical reflection on the view on children that we should adopt, and by consulting minors themselves about the perspectives on their role in decision-making. Finally, based on this research, recommendations are provided on how to empower minors in decision-making about research participation.

Published
2016

25. The Incidence of Post-Electroconvulsive Therapy Headache

Author

Mulder, Laura Aleida Christina and Grootens, Koen Pieter

Abstract

Supplemental digital content is available in the text.Headache is a common side effect of electroconvulsive therapy (ECT), but reports on its incidence vary widely. A broad array of treatment regimens have been proposed in the literature. The pathophysiology of post-ECT headache is unclear but a vascular origin has been suggested. A systematic literature search was executed in PubMed and Embase to identify relevant articles. Articles were screened on title, abstract, and full text according to predefined inclusion and exclusion criteria. Study characteristics and results concerning the incidence of post-ECT headache were extracted, and a weighted mean incidence was calculated. Forty-seven relevant articles were found, of which 36 reported on the incidence of post-ECT headache in patients and 9 on the incidence in sessions. The incidence of post-ECT headache varied greatly in the literature. The weighted mean incidence in patients was 32.8%, as 786 of a total population of 2399 patients experienced headache. The weighted mean incidence in sessions was between 9.4% (246 of 2604 sessions) and 12.1% (236/1958 sessions). The variation in incidences of post-ECT headache found might be due to different methods of measuring headache, different study designs, and different drugs used for anesthesia. The mean-weighted incidence of post-ECT headache in patients was 32.8% and in sessions between 9.4% and 12.1%.

Published
2020
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26. Deciphering the differentiation trajectory from hematopoietic stem cells to mast cells

Author

Grootens, Jennine, Ungerstedt, Johanna S., Nilsson, Gunnar, and Dahlin, Joakim S.

Abstract

Hematopoietic stem cells differentiate into all types of blood cells, including peripheral tissue-resident mast cells. The early mast cell differentiation takes place in the bone marrow, after which the progenitor cells enter the circulation and mature once reaching their target organ. Early results from single-cell culture experiments and colony-forming assays have produced the classic hierarchical tree model of hematopoiesis. The introduction of high-throughput, single-cell RNA sequencing is now revolutionizing our understanding of the differentiation process, questioning the classic tree-based models. By integrating the results from early cell culture experiments with single-cell transcriptomics, we present a differentiation landscape model of hematopoiesis and discuss it with focus on mast cells. The review also describes how the hematologic neoplasm systemic mastocytosis can be used to model human hematopoiesis using naturally occurring cell barcoding by means of the common KITD816V mutation.

Published
2018
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27. KIT signaling is dispensable for human mast cell progenitor development

Author

Dahlin, Joakim S., Ekoff, Maria, Grootens, Jennine, Löf, Liza, Amini, Rose-Marie, Hagberg, Hans, Ungerstedt, Johanna S., Olsson-Strömberg, Ulla, and Nilsson, Gunnar

Abstract

Human hematopoietic progenitors are generally assumed to require stem cell factor (SCF) and KIT signaling during differentiation for the formation of mast cells. Imatinib treatment, which inhibits KIT signaling, depletes mast cells in vivo. Furthermore, the absence of SCF or imatinib treatment prevents progenitors from developing into mast cells in vitro. However, these observations do not mean that mast cell progenitors require SCF and KIT signaling throughout differentiation. Here, we demonstrate that circulating mast cell progenitors are present in patients undergoing imatinib treatment. In addition, we show that mast cell progenitors from peripheral blood survive, mature, and proliferate without SCF and KIT signaling in vitro. Contrary to the prevailing consensus, our results show that SCF and KIT signaling are dispensable for early mast cell development.

Published
2017
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28. On the use of positive test strategies when diagnosing mental disorders.

Author

van der Heijden, Paul T., Cefo, Irma, Witteman, Cilia L.M., and Grootens, Koen P.

Abstract

Despite the adverse impact diagnostic errors can have, clinical interviewing and decision-making in psychiatric practice have received relatively little empirical attention. When diagnosing patients, clinicians tend to fall back on a specific (heuristic) rule of thumb, the positive test strategy, a confirmatory approach that increases the risk of confirmation bias. A group of 83 clinical psychologists and psychiatrists was asked to give their diagnostic hypotheses about two vignettes. We found them to self-generate significantly (i.e., p <.01; d = 1.57) more confirming than disconfirming questions to test their initial diagnostic impressions, with supervisors considering significantly more differential diagnoses than the less experienced post-grads/residents. When offered a list of 100 potentially relevant diagnostic queries, the supervisors selected fewer confirming and proportionally more disconfirming themes. Our results demonstrate that irrespective of clinical experience mental-health clinicians indeed tend to use a confirmatory thinking style that contrasts with the stricter principle of falsification. More field-based research on this topic is needed, as well as studies probing whether a systematized diagnostic approach is feasible in psychiatric practice and increases diagnostic accuracy and patient satisfaction. • Clinical decision-making in psychiatry may suffer from the use of heuristics. • Confirmatory and positive test strategies raise the risk of confirmation bias. • The principle of falsification may bolster the diagnostic process. • Systematizing diagnostic interviews and disconfirmatory queries are recommended. [ABSTRACT FROM AUTHOR]

Published
2022
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29. An expert-supported monitoring system for patients with chronic obstructive pulmonary disease in general practice: results of a cluster randomised controlled trial.

Author

Van den Bemt, Lisette, Schermer, Tjard R. J., Smeele, Ivo J. M., Boonman-de Winter, Leandra, Van Boxem, Ton, Denis, Joke, Grootens-Stekelenburg, Joke G., Grol, Richard P. T. M., and Van Weel, Chris

Abstract

The article presents information on a cluster randomized controlled trial which determined whether general practice monitoring system with respiratory expert recommendations for general practitioners' management of patients with chronic obstructive monitoring disease (COPD) is effective long-term. The trial which was conducted from July 2005 to February 2008 involved 200 participants in the south-western region of the Netherlands. Analysis of the research findings indicate the ineffectiveness of an expert-supported monitoring system for COPD patients.

Published
2009
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34. Raloxifene augmentation in men and women with a schizophrenia spectrum disorder: A study protocol

Author

Brand, Bodyl A., de Boer, Janna N., Oude Ophuis, Sebastianus B.J., Slot, Margot I.E., De Wilde, Bieke, Catthoor, Kirsten C.E.E.R., Goverde, Angelique J., Bakker, P. Roberto, Marcelis, Machteld C., Grootens, Koen P., Luykx, Jurjen J., Heringa, Sophie M., Weickert, Cynthia Shannon, Sommer, Iris E.C., and Weickert, Thomas W.

Abstract

Although acute psychotic symptoms are often reduced by antipsychotic treatment, many patients with schizophrenia are impaired in daily functioning due to the persistence of negative and cognitive symptoms. Raloxifene, a Selective Estrogen Receptor Modulator (SERM) has been shown to be an effective adjunctive treatment in schizophrenia. Yet, there is a paucity in evidence for raloxifene efficacy in men and premenopausal women. We report the design of a study that aims to replicate earlier findings concerning the efficacy of raloxifene augmentation in reducing persisting symptoms and cognitive impairment in postmenopausal women, and to extend these findings to a male and peri/premenopausal population of patients with schizophrenia. The study is a multisite, placebo-controlled, double-blind, randomised clinical trial in approximately 110 adult men and women with schizophrenia. Participants are randomised 1:1 to adjunctive raloxifene 120 mg or placebo daily during 12 weeks. The treatment phase includes measurements at three time points (week 0, 6 and 12), followed by a follow-up period of two years. The primary outcome measure is change in symptom severity, as measured with the Positive and Negative Syndrome Scale (PANSS), and cognition, as measured with the Brief Assessment of Cognition in Schizophrenia (BACS). Secondary outcome measures include social functioning and quality of life. Genetic, hormonal and inflammatory biomarkers are measured to assess potential associations with treatment effects. If it becomes apparent that raloxifene reduces psychotic symptoms and/or improves cognition, social functioning and/or quality of life as compared to placebo, implementation of raloxifene in clinical psychiatric practice can be considered.

Published
2020
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35. Toeleiding naar en voltooiing van leefstijlinterventies voor kinderen met overgewicht en obesitas

Author

Grootens, P., Emma van den Eynde, Jutka Halberstadt, Niemer, S. I. J., jacob Seidell, Dedding, C. W. M., Athena Institute, and Youth and Lifestyle

Abstract

In het onderzoek ‘Toeleiding naar en voltooiing van leefstijlinterventies voor kinderen met overgewicht en obesitas’ blijkt dat succesvolle toeleiding en voltooiing van leefstijlinterventies niet een kwestie is van de aan- of afwezigheid van één bepaalde factor, maar dat het succesvol starten en afronden van een interventie pas plaatsvindt wanneer de relevante factoren overwegend faciliterend zijn en/of opwegen tegen de belemmerende factoren. Het is uiteindelijk de positieve balans tussen de ervaren barrières en de faciliterende factoren die ervoor zorgt dat mensen een programma voltooien. Barrières zijn onderdeel van het uitdagende leven van deze gezinnen en niet eenvoudig oplosbaar. De kunst is om de barrières daar waar mogelijk te verkleinen én de faciliterende factoren te versterken. Dit onderzoek, wat uitgevoerd is in opdracht van de Amsterdamse Aanpak Gezond Gewicht, levert daartoe belangrijke handvatten

36. BOEKBESPEKINGEN

Author

de la Potterie, I., primary, de la Porterie, I., additional, de la Potterie, I., additional, Smulders, P., additional, Ploumen, P., additional, Fransen, P., additional, Monden, L., additional, Sträter, C., additional, Van Torre, J., additional, Grootens, P., additional, v. Kol, A., additional, Snoeck, A., additional, Rietmeyer, J., additional, Mulders, J., additional, De Munter, J., additional, van Doornik, P., additional, Crick, J., additional, Rupert, J., additional, Loyens, R., additional, Malmberg, F., additional, Trooster, S., additional, Hostie, R., additional, Nota, J., additional, Poncelet, A., additional, Kerken, L. Vander, additional, Couturier, W., additional, de Bruin, P., additional, Jansen, L., additional, Peeters, J., additional, De Pelsemaeker, A., additional, and Deblaere, A., additional

Published
1955
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37. BOEKBESPREKINGEN

Author

De Fraine, J., primary, De Fraine, J., additional, Somers, H., additional, Vanneste, J., additional, de la Potterie, I., additional, Mulders, J., additional, Leys, R., additional, Ploumen, P., additional, Grootens, P., additional, Rupert, J., additional, Dierickx, M., additional, Boelens, W., additional, Fransen, P., additional, Van Torre, J., additional, Kerken, L. Vander, additional, van Leeuwen, A., additional, Nota, J., additional, Huybens, M., additional, Verhaar, J., additional, Hostie, R., additional, Kerkhofs, J., additional, Oudshoorn, H., additional, v. Doornik, P., additional, van Doornik, P., additional, and Depoorter, J., additional

Published
1958
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38. BOEKBESPREKINGEN

Author

Ahsmann, P., primary, Van Torre, J., additional, van Doornik, P., additional, De Fraine, J., additional, Verbeke, J., additional, Smulders, P., additional, Jans, H., additional, Grootens, P., additional, Fransen, P., additional, Kerkhofs, J., additional, Beyer, J., additional, Vanneste, J., additional, Vercruysse, J., additional, Boelens, W., additional, Huybens, M., additional, Nota, J. H., additional, Poncelet, A., additional, Couturier, W., additional, Huffer, E., additional, Defever, J., additional, Jacqmotte, G., additional, Kijm, J. M., additional, Beukers, Cl., additional, Dierickx, M., additional, Achten, G., additional, De Cock, J., additional, Ploumen, P., additional, and Bolsius, E., additional

Published
1960
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40. BOEKBESPREKINGEN

Author

van Doornik, P., primary, Ahsmann, P., additional, Klijn, W., additional, de Strycker, E., additional, Fransen, P., additional, Smulders, P., additional, Vanneste, J., additional, Beyer, J., additional, Ploumen, P., additional, van Kol, A., additional, van Doornik, P., additional, Houben, J. J., additional, Nota, J. H., additional, van Leeuwen, A., additional, Bisschop, L. Steins, additional, Huffer, E., additional, Dupré, L., additional, Geraets, Th. F., additional, De Tollenaere, M., additional, Kijm, J., additional, Braeckmans, L., additional, Kerkhofs, J., additional, Dierickx, M., additional, Van Ommeslaeghe, F., additional, Kerken, L. Vander, additional, and Grootens, P., additional

Published
1959
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41. BOEKBESPREKINGEN

Author

Fransen, P., primary, Ahsmann, P., additional, De Fraine, J., additional, van Doornik, P., additional, Vandenbunder, A., additional, Fransen, P., additional, Quecke, H., additional, Mulders, J., additional, Van Schoote, J. P., additional, Kerkhofs, J., additional, Ploumen, P., additional, van Kol, A., additional, Vanneste, J., additional, Dierickx, M., additional, Leuridan, H., additional, Grootens, P., additional, Bots, J., additional, Kerssemakers, J. W., additional, Huffer, E., additional, Morlion, H., additional, Kerken, L. Vander, additional, Le Grelle, G., additional, De Tollenaere, M., additional, van Bladel, L., additional, Hostie, R., additional, Kijm, J., additional, Braeckmans, L., additional, and de Brabanter, L., additional

Published
1960
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42. BOEKBESPREKINGEN

Author

Tison, J. M., primary, Tison, J.-M., additional, Fransen, P., additional, D'hondt, R., additional, Boelens, W., additional, Trooster, S., additional, Vanneste, J., additional, Ploumen, P., additional, Kerkhofs, J., additional, De Smet, S., additional, Vercruysse, J., additional, Nota, J., additional, Poncelet, A., additional, De Tollenaere, M., additional, Verhaak, C., additional, van der Lee, H., additional, Sprokel, N., additional, Couturier, W., additional, Robbers, H., additional, Somers, H., additional, Cuvelier, F., additional, Schreiner, G., additional, Grootens, P., additional, and Barten, J., additional

Published
1964
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43. BOEKBESPREKINGEN

Author

De Fraine, J., primary, De Fraine, J., additional, Fransen, P., additional, de la Potterie, I., additional, Leys, R., additional, Vanneste, J., additional, Trooster, S., additional, Malmberg, F., additional, Ploumen, P., additional, Meddens, H., additional, van Kol, A., additional, van Leeuwen, A., additional, Van Torre, J., additional, Dierickx, M., additional, Mulders, J., additional, Nota, J. H., additional, Robbers, H., additional, Van Bladel, L., additional, De Cock, J., additional, van Doornik, P., additional, Hostie, R., additional, Schreiner, G., additional, Grootens, P., additional, De Wachter, M., additional, and Lambrecht, J., additional

Published
1959
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44. BOEKBESPREKINGEN

Author

Walle, R. Vande, primary, Bakker, L., additional, Tison, J.-M., additional, Fransen, P., additional, De Fraine, J., additional, Poncelet, A., additional, Vanneste, J., additional, Deblaere, A., additional, Bossuyt, F., additional, Grootens, P., additional, van Doornik, P., additional, Trooster, S., additional, Kerkhofs, J., additional, Boelens, W., additional, Vercruysse, J., additional, Robbers, H., additional, Geurtsen, H., additional, Sprokel, N., additional, Nota, J., additional, Verhaak, C., additional, De Tollenaere, M., additional, Somers, H., additional, Verhaar, F., additional, Cauwelier, A., additional, Beukers, Cl., additional, and De Haes, R., additional

Published
1964
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45. BOEKBESPREKINGEN

Author

De Fraine, J., primary, De Fraine, J., additional, de la Potterie, I., additional, Mulders, J., additional, Smulders, P., additional, Leys, R., additional, Somers, H., additional, Verbeeckx, L., additional, Snoeck, A., additional, Trooster, S., additional, Fransen, P., additional, van Kol, A., additional, De Munter, J., additional, Achten, G., additional, Grootens, P., additional, Dierickx, M., additional, Rupert, J., additional, Geurtsen, H., additional, Houben, A., additional, Bisschop, L. Steins, additional, Malmberg, F., additional, v. d. Lee, H., additional, De Raedemaeker, F., additional, van Leeuwen, A., additional, Nota, J., additional, Poncelet, A., additional, Couturier, W., additional, Kerken, L. Vander, additional, Vandenbussche, Fr., additional, Hostie, R., additional, Verbeek, H., additional, van Doornik, P., additional, Ploumen, P., additional, Torfs, F., additional, and Dykmans, M., additional

Published
1957
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46. BOEKBESPREKINGEN

Author

Volckaert, J., primary, De Fraine, J., additional, de la Potterie, I., additional, Smulders, P., additional, Malmberg, F., additional, Knockaert, A., additional, Dykmans, M., additional, Rupert, J., additional, Ploumen, P., additional, Fransen, P., additional, Sträter, C., additional, Loyens, R., additional, Snoeck, A., additional, Lenaers, R., additional, Rietmeyer, J., additional, Kottaram, Th., additional, Dierickx, M., additional, Van Torre, J., additional, van Doornik, P., additional, De Raedemaeker, F., additional, van Leeuwen, A., additional, Bisschop, L. Steins, additional, Kerken, L. Vander, additional, De Tollenaere, M., additional, Geurtsen, H., additional, Poncelet, A., additional, Raignier, A., additional, Mulder, Th., additional, Hostie, R., additional, van Bulck, V., additional, Zwetsloot, H., additional, and Grootens, P., additional

Published
1955
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47. BOEKBESPREKINGEN

Author

Tison, J.-M., primary, Tison, J.-M., additional, Tillmans, F., additional, Fransen, P., additional, Van Waelderen, Eddy, additional, De Schrijver, G., additional, de Grijs, F., additional, Leijen, A. J., additional, Vercruysse, Jos, additional, Grootens, P., additional, Berghs, H., additional, Poncelet, A., additional, Scheltens, D., additional, Boey, K., additional, Derksen, A. A., additional, Baekelandt, A., additional, Ceusters, R., additional, Hostie, R., additional, De Smet, S., additional, Kerckhof, E., additional, de Strycker, E., additional, and De Graeve, Frank, additional

Published
1971
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48. BOEKBESPREKINGEN

Author

De Fraine, J., primary, De Fraine, J., additional, van Doornik, P., additional, Tison, J.-M., additional, Fransen, P., additional, Traets, C., additional, Trooster, S., additional, de Fraine, J., additional, Raes, St., additional, Appleyard, J., additional, Kerkhofs, J., additional, Bossuyt, F., additional, Bakker, L., additional, Monden, L., additional, De Tollenaere, M., additional, van Kol, A., additional, Braeckmans, L., additional, Grootens, P., additional, Dierickx, M., additional, Van Torre, J., additional, Vercruysse, J., additional, Boelens, W., additional, Verhaak, C., additional, Kijm, J., additional, Vandenbussche, F., additional, Van Bladel, L., additional, Kerken, L. Vander, additional, Beukers, Cl., additional, De Graeve, F., additional, Vanneste, J., additional, Hoefnagels, H., additional, and Penning de Vries, P., additional

Published
1965
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49. BOEKBESPREKINGEN

Author

Tison, J.-M., primary, Tison, J.-M., additional, de Kruljf, Th. C., additional, Mennes, R., additional, Fransen, P., additional, Van Dorpe, Bernard, additional, Van Dorpe, B., additional, Vercruysse, Jos, additional, Tillmans, F., additional, Verhaak, C., additional, Poncelet, A., additional, Leijen, A. J., additional, Swüste, G., additional, Nota, J. H., additional, Hostie, R., additional, van Doornik, P., additional, and Grootens, P., additional

Published
1969
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50. BOEKBESPREKINGEN

Author

Ahsmann, P., primary, De Fraine, J., additional, Tison, T.-M., additional, Tison, J.-M., additional, Beuken, W., additional, D'hondt, R., additional, van Kol, A., additional, Fransen, P., additional, Grootens, P., additional, Mulders, J., additional, Kerkhofs, J., additional, Bossuyt, F., additional, Dierickx, M., additional, Vercruysse, J., additional, Verhaak, C., additional, Kerken, L. Vander, additional, Geurtsen, H., additional, Van Bladel, L., additional, van der Lee, H., additional, De Tollenaere, M., additional, Meddens, H., additional, Vandenbussche, Frans, additional, Schreiner, G., additional, de Strycker, E., additional, van Doornik, P., additional, Cuvelier, F., additional, Janssen, Em., additional, and Janssen, E., additional

Published
1963
Full Text
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