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4. Intima-media thickness at the near or far wall of the common carotid artery in cardiovascular risk assessment

Author

Seekircher, Lisa, primary, Tschiderer, Lena, additional, Lind, Lars, additional, Safarova, Maya S, additional, Kavousi, Maryam, additional, Ikram, M Arfan, additional, Lonn, Eva, additional, Yusuf, Salim, additional, Grobbee, Diederick E, additional, Kastelein, John J P, additional, Visseren, Frank L J, additional, Walters, Matthew, additional, Dawson, Jesse, additional, Higgins, Peter, additional, Agewall, Stefan, additional, Catapano, Alberico, additional, de Groot, Eric, additional, Espeland, Mark A, additional, Klingenschmid, Gerhard, additional, Magliano, Dianna, additional, Olsen, Michael H, additional, Preiss, David, additional, Sander, Dirk, additional, Skilton, Michael, additional, Zozulińska-Ziółkiewicz, Dorota A, additional, Grooteman, Muriel P C, additional, Blankestijn, Peter J, additional, Kitagawa, Kazuo, additional, Okazaki, Shuhei, additional, Manzi, Maria V, additional, Mancusi, Costantino, additional, Izzo, Raffaele, additional, Desvarieux, Moise, additional, Rundek, Tatjana, additional, Gerstein, Hertzel C, additional, Bots, Michiel L, additional, Sweeting, Michael J, additional, Lorenz, Matthias W, additional, and Willeit, Peter, additional

Published
2023
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10. Long-term peridialytic blood pressure changes are related to mortality.

Author

Zuijdewijn, Camiel L M de Roij van, Rootjes, Paul A, Nubé, Menso J, Bots, Michiel L, Canaud, Bernard, Blankestijn, Peter J, Ittersum, Frans J van, Maduell, Francisco, Morena, Marion, Peters, Sanne A E, Davenport, Andrew, Vernooij, Robin W M, Grooteman, Muriel P C, and investigators, the HDF Pooling Project

Subjects
BLOOD pressure, MORTALITY, ABSOLUTE value
Abstract

Background In chronic haemodialysis (HD) patients, the relationship between long-term peridialytic blood pressure (BP) changes and mortality has not been investigated. Methods To evaluate whether long-term changes in peridialytic BP are related to mortality and whether treatment with HD or haemodiafiltration (HDF) differs in this respect, the combined individual participant data of three randomized controlled trials comparing HD with HDF were used. Time-varying Cox regression and joint models were applied. Results During a median follow-up of 2.94 years, 609 of 2011 patients died. As for pre-dialytic systolic BP (pre-SBP), a severe decline (≥21 mmHg) in the preceding 6 months was independently related to increased mortality [hazard ratio (HR) 1.61, P  = .01] when compared with a moderate increase. Likewise, a severe decline in post-dialytic diastolic BP (DBP) was associated with increased mortality (adjusted HR 1.96, P  < .0005). In contrast, joint models showed that every 5-mmHg increase in pre-SBP and post-DBP during total follow-up was related to reduced mortality (adjusted HR 0.97, P  = .01 and 0.94, P  = .03, respectively). No interaction was observed between BP changes and treatment modality. Conclusion Severe declines in pre-SBP and post-DBP in the preceding 6 months were independently related to mortality. Therefore peridialytic BP values should be interpreted in the context of their changes and not solely as an absolute value. [ABSTRACT FROM AUTHOR]

Published
2023
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16. The probability of receiving a kidney transplantation in end-stage kidney disease patients who are treated with haemodiafiltration or haemodialysis : a pooled individual participant data from four randomised controlled trials

Author

Vernooij, Robin W. M., Law, Way, Peters, Sanne A. E., Canaud, Bernard, Davenport, Andrew, Grooteman, Muriel P. C., Kircelli, Fatih, Locatelli, Francesco, Maduell, Francisco, Morena, Marion, Nubé, Menso J., Ok, Ercan, Torres, Ferran, Woodward, Mark, Blankestijn, Peter J., Bots, Michiel L., Vernooij, Robin W. M., Law, Way, Peters, Sanne A. E., Canaud, Bernard, Davenport, Andrew, Grooteman, Muriel P. C., Kircelli, Fatih, Locatelli, Francesco, Maduell, Francisco, Morena, Marion, Nubé, Menso J., Ok, Ercan, Torres, Ferran, Woodward, Mark, Blankestijn, Peter J., and Bots, Michiel L.

Abstract

UDBELLATERRA, Due to a critical shortage of available kidney grafts, most patients with Stage 5 Chronic Kidney Disease (CKD5) require bridging dialysis support. It remains unclear whether treatment by different dialysis modalities changes the selection and/or preparation of a potential transplant candidate. Therefore, we assessed whether the likelihood of receiving kidney transplant (both living or deceased kidney donors) differs between haemodialysis (HD) and online haemodiafiltration (HDF) in patients with CKD5D. Individual participant data from four randomised controlled trials comparing online HDF with HD were used. Information on kidney transplant was obtained during follow-up. The likelihood of receiving a kidney transplant was compared between HD and HDF, and evaluated across different subgroups: age, sex, diabetes, history of cardiovascular disease, albumin, dialysis vintage, fistula, and level of convection volume standardized to body surface area. Hazard ratios (HRs), with corresponding 95% confidence intervals (95% CI), comparing the effect of online HDF versus HD on the likelihood of receiving a kidney transplant, were estimated using Cox proportional hazards models with a random effect for study. After a median follow-up of 2.5 years (Q1 to Q3: 1.9-3.0), 331 of the 1620 (20.4%) patients with CKD5D received a kidney transplant. This concerned 22% (n = 179) of patients who were treated with online HDF compared with 19% (n = 152) of patients who were treated with HD. No differences in the likelihood of undergoing a kidney transplant were found between the two dialysis modalities in both the crude analyse (HR: 1.07, 95% CI: 0.86-1.33) and adjusted analysis for age, sex, diabetes, cardiovascular history, albumin, and creatinine (HR: 1.15, 95%-CI: 0.92-1.44). There was no evidence for a differential effect across subgroups based on patient- and disease-characteristics nor in different categories of convection volumes. Treatment with HD and HDF does not affect the selection

Published
2021

21. Why and how high volume hemodiafiltration may reduce cardiovascular mortality in stage 5 chronic kidney disease dialysis patients? A comprehensive literature review on mechanisms involved.

Author

Canaud, Bernard, Blankestijn, Peter J., Grooteman, Muriel P. C., and Davenport, Andrew

Subjects
CHRONIC kidney failure, HEMODIALYSIS patients, HEMODIALYSIS, ENDOTHELIUM diseases, HEMODIAFILTRATION, BLOOD volume
Abstract

Online hemodiafiltration (HDF) is an established renal replacement modality for patients with end stage chronic kidney disease that is now gaining rapid clinical acceptance worldwide. Currently, there is a growing body of evidence indicating that treatment with HDF is associated with better outcomes and reduced cardiovascular mortality for dialysis patients. In this comprehensive review, we provide an update on the potential mechanisms which may improve survival in HDF treated patients. The strongest evidence is for better hemodynamic stability and reduced endothelial dysfunction associated with HDF treatments. Clinically, this is marked by a reduced incidence of intradialytic hypotensive episodes, with a better hemodynamic response to ultrafiltration, mediated by an increase in total peripheral vascular resistance and extra‐vascular fluid recruitment, most likely driven by the negative thermal balance associated with online HDF therapy. In addition, endothelial function appears to be improved due to a combination of a reduction of the inflammatory and oxidative stress complex syndrome and exposure to circulating cardiovascular uremic toxins. Reports of reversed cardiovascular remodeling effects with HDF may be confounded by volume and blood pressure management, which are strongly linked to center clinical practices. Currently, treatment with HDF appears to improve the survival of dialysis patients predominantly due to a reduction in their cardiovascular burden, and this reduction is linked to the sessional convection volume exchanged. [ABSTRACT FROM AUTHOR]

Published
2022
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23. HDF promise for the future

Author

van der Weerd, Neelke C., Penne, E. Lars, van den Dorpel, Marinus A., Grooteman, Muriel P. C., Nubé, Menso J., Bots, Michiel L., ter Wee, Piet M., and Blankestijn, Peter J.

Published
2008

30. Change in FGF23 concentration over time and its association with all-cause mortality in patients treated with haemodialysis or haemodiafiltration.

Author

Krijger, Annet Bouma-de, Zuijdewijn, Camiel L M de Roij van, Nubé, Menso J, Grooteman, Muriel P C, Vervloet, Marc G, and Group, the CONTRAST Study

Subjects
FIBROBLAST growth factors, HEMODIALYSIS patients, TREATMENT effectiveness
Abstract

Background Previous studies in patients on haemodialysis (HD) have shown an association of fibroblast growth factor 23 (FGF23) with all-cause mortality. As of yet, the result of FGF23 lowering on mortality is unknown in this population. Methods FGF23 was measured in a subset of 404 patients from the Dutch CONvective TRansport STudy (CONTRAST study) [a randomized trial in prevalent dialysis patients comparing HD and haemodiafiltration (HDF) with clinical outcome] at baseline and Months 6 and 12. A substantial decline of FGF23 change over time was anticipated in patients randomized to HDF since HDF induces higher dialytic clearance of FGF23. The associations of both baseline FGF23 and 6-months change in FGF23 with all-cause mortality were analysed. In addition, the difference in FGF23 change between HD and HDF was explored. Furthermore, the role of dialysis modality in the association between FGF23 change and outcome was analysed. Results No association was observed between quartiles of baseline FGF23 and all-cause mortality. Over 6 months, FGF23 declined in patients on HDF, whereas FGF23 remained stable in patients on HD. A decrease in FGF23 was not associated with improved survival compared with a stable FGF23 concentration. However, increasing FGF23 was associated with a significantly higher mortality risk, both in crude and fully adjusted models [hazard ratio 2.01 (95% confidence interval 1.30–3.09)]. Conclusion Whereas no association between a single value of FGF23 and all-cause mortality was found, increasing FGF23 concentrations did identify patients at risk for mortality. Since lowering FGF23 did not improve outcome, this study found no argument for therapeutically lowering FGF23. [ABSTRACT FROM AUTHOR]

Published
2021
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31. Mortality reduction by post-dilution online-haemodiafiltration: a cause-specific analysis

Author

Nubé, Menso J., Peters, Sanne A E, Blankestijn, Peter J., Canaud, Bernard, Davenport, Andrew, Grooteman, Muriel P C, Asci, Gulay, Locatelli, Francesco, Maduell, Francisco, Morena, Marion, Ok, Ercan, Torres, Ferran, Bots, Michiel L., Moreso, Francesc, Pons, Mercedes, Ramos, Rosa, Mora-Macià, Josep, Carreras, Jordi, Soler, Jordi, Campistol, Josep M., Martinez-Castelao, Alberto, Insensé, B., Perez, C., Feliz, T., Barbetta, M., Soto, C., Mora, J., Juan, A., Ibrik, O., Foraster, A., Nin, J., Fernández, A., Arruche, M., Sánchez, C., Vidiella, J., Barbosa, F., Chiné, M., Hurtado, S., Llibre, J., Ruiz, A., Serra, M., Salvó, M., Poyuelo, T., Maduell, F., Carrera, M., Fontseré, N., Arias, M., Merín, A., Ribera, L., Galceran, J. M., Mòdol, J., Moliner, E., Ramirez, A., Aguilera, J., Alvarez, M., De La Torre, B., Molera, M., Casellas, J., Martín, G., Andres, E., Coll, E., Valles, M., Martínez, C., Castellote, E., Casals, J. M., Gabàs, J., Romero, M., Martinez-Castelao, A., Fulladosa, X., Ramirez-Arellano, M., Fulquet, M., Pelegrí, A., El Manouari, M., Ramos, N., Bartolomé, J., Sans, R., Fernández, E., Sarró, F., Compte, T., Marco, F., Mauri, R., Bronsoms, J., Arnaiz, J. A., Beleta, H., Pejenaute, A., Ríos, J., Lara, J., Ter Wee, P. M., Van Den Dorpel, M. A., Dorval, M., Lévesque, R., Koopman, M. G., Konings, C. J A M, Haanstra, W. P., Kooistra, M., Van Jaarsveld, B., Noordzij, T., Feith, G. W., Peltenburg, H. G., Van Buren, M., Offerman, J. J G, Hoogeveen, E. K., De Heer, F., Van De Ven, P. J., Kremer Hovinga, T. K., Bax, W. A., Groeneveld, J. O., Lavrijssen, A. T J, Schrander-Van Der Meer, A. M., Reichert, L. J M, Huussen, J., Rensma, P. L., Schrama, Y., Van Hamersvelt, H. W., Boer, W. H., Van Kuijk, W. H., Vervloet, M. G., Wauters, I. M P M J, Sekse, I., Toz, Huseyin, Ok, Ebru Sevinc, Kircelli, Fatih, Yilmaz, Mumtaz, Hur, Ender, Demirci, Meltem Sezis, Demirci, Cenk, Duman, Soner, Basci, Ali, Adam, Siddig Momin, Isik, Ismet Onder, Zengin, Murat, Suleymanlar, Gultekin, Yilmaz, Mehmet Emin, Ergin, Mehmet Ozkahya Pinar, Sagdic, Alfert, Kayali, Erkan, Boydak, Can, Colak, Taskin, Caliskan, Sihli, Kaplan, Hakan, Ulas, Hasibe, Kirbiyik, Sait, Berktas, Hakan, Dilbaz, Necati, Cristol, Jean Paul, Leray-Moragues, Hélène, Chenine, Leïla, Picot, Marie Christine, Jaussent, Audrey, Belloc, Claire, Lagarrigue, Mélodie, Chalabi, Lotfi, Debure, Alain, Ouziala, Messaoud, Lefevre, Jean Jacques, Thibaudin, Damien, Mohey, Hesham, Broyet, Christian, Afiani, Aida, Serveaux, Marie Odile, Patrier, Laure, Maurice, François, Rivory, Jean Pierre, Nicoud, Philippe, Durand, Claude, Normand, Michel, Seigneuric, Bruno, Magnant, Eric, Azzouz, Lynda, Islam, Mohamed Shariful, Vido, Sandor, Nzeyimana, Hilaire, Simonin, Danièle, Azymah, Yamina, Farah, Ibrahim, Coindre, Jean Philippe, Puyoo, Olivier, Chabannier, Marie Hélène, Ibos, Richard, Rouleau, Fabienne, Vela, Carlos, Joule, Josiane, Combarnous, François, Turc-Baron, Cécile, Ducret, Francis, Pointet, Philippe, Rey, Isabelle, Potier, Jacky, Bendini, Jean Christophe, Perrin, Franck, Kunz, Kristian, Lefrancois, Gaëlle, Colin, Angélique, Parahy, Sophie, Dancea, Irima, Coupel, Stéphanie, Testa, Angelo, Brunet, Philippe, Lebrun, Gaétan, Jaubert, Dominique, Delcroix, Catherine, Lavainne, Frédéric, Lefebvre, Anne, Guillodo, Marie Paule, Le Grignou, Dominique, Djema, Assia, Maaz, Mehadji, Chiron, Sylvie, Hoffmann, Maxime, Depraetre, Pascale, Haddj-Elmrabet, Atman, Joyeux, Véronique, Fleury, Dominique, Vrigneaud, Laurence, Lemaitre, Vincent, Aguilera, Didier, Guerraoui, Abdallah, Cremault, Alain, Laradi, Achour, Babinet, Francois, VU University Medical Center [Amsterdam], University of Oxford [Oxford], University Medical Center [Utrecht], Fresenius Medical Care Deutschland, University College of London [London] (UCL), Ege university, Alessandro Manzoni Hospital, Hospital Clinic Barcelona, Physiologie & médecine expérimentale du Cœur et des Muscles [U 1046] (PhyMedExp), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Universitat Autònoma de Barcelona (UAB), Ege Üniversitesi, Nephrology, ICaR - Circulation and metabolism, Herrada, Anthony, and University of Oxford

Subjects
Male, medicine.medical_specialty, 030232 urology & nephrology, Hemodiafiltration, 030204 cardiovascular system & hematology, haemodiafiltration, Convection, Lower risk, Sudden death, convection volume, [SDV.MHEP.UN]Life Sciences [q-bio]/Human health and pathology/Urology and Nephrology, haemo-diafiltration, 03 medical and health sciences, 0302 clinical medicine, Renal Dialysis, cardiovascular disease, Cause of Death, Internal medicine, Journal Article, medicine, Humans, Intensive care medicine, Aged, Proportional Hazards Models, Randomized Controlled Trials as Topic, Transplantation, integumentary system, business.industry, Mortality rate, Hazard ratio, Middle Aged, [SDV.MHEP.UN] Life Sciences [q-bio]/Human health and pathology/Urology and Nephrology, mortality, Confidence interval, 3. Good health, meta-analysis, Cardiovascular Diseases, Nephrology, Meta-analysis, Cardiology, Number needed to treat, Kidney Failure, Chronic, Female, business
Abstract

WOS: 000398117600023, PubMed ID: 28025382, Background. From an individual participant data (IPD) meta-analysis from four randomized controlled trials comparing haemodialysis (HD) with post-dilution online-haemodiafiltration (ol-HDF), previously it appeared that HDF decreases all-cause mortality by 14% (95% confidence interval 25; 1) and fatal cardiovascular disease (CVD) by 23% (39; 3). Significant differences were not found for fatal infections and sudden death. So far, it is unclear, however, whether the reduced mortality risk of HDF is only due to a decrease in CVD events and if so, which CVD in particular is prevented, if compared with HD. Methods. The IPD base was used for the present study. Hazard ratios and 95% confidence intervals for cause-specific mortality overall and in thirds of the convection volume were calculated using the Cox proportional hazard regression models. Annualized mortality and numbers needed to treat (NNT) were calculated as well. Results. Besides 554 patients dying from CVD, fatal infections and sudden death, 215 participants died from 'other causes', such as withdrawal from treatment and malignancies. In this group, the mortality risk was comparable between HD and ol-HDF patients, both overall and in thirds of the convection volume. Subdivision of CVD mortality in fatal cardiac, non-cardiac and unclassified CVD showed that ol-HDF was only associated with a lower risk of cardiac casualties [0.64 (0.61; 0.90)]. Annual mortality rates also suggest that the reduction in CVD death is mainly due to a decrease in cardiac fatalities, including both ischaemic heart disease and congestion. Overall, 32 and 75 patients, respectively, need to be treated by high-volume HDF (HV-HDF) to prevent one all-cause and one CVD death, respectively, per year. Conclusion. The beneficial effect of ol-HDF on all-cause and CVD mortality appears to be mainly due to a reduction in fatal cardiac events, including ischaemic heart disease as well as congestion. In HV-HDF, the NNT to prevent one CVD death is 75 per year., EuDial working group; European Nephrology and Dialysis Institute; Catalan Society of Nephrology; Fresenius Medical Care; Dutch Kidney Foundation [C02.2019]; Fresenius Medical Care, Netherlands; Gambro Lundia AB, Sweden; Dr E.E. Twiss Fund; International Society of Nephrology/Baxter Extramural Grant Program; Netherlands Organization for Health Research and DevelopmentNetherlands Organization for Health Research and Development [170882802]; national grant from the Health Ministry (Programme Hospitalier de Recherche Clinique, PHRC); Gambro through the Catalan Society of Nephrology; Roche Netherlands, The HDF Pooling project was designed, conducted and analysed independently of the financial contributors of the individual studies as listed below. Study data were collected and retained by the investigators and were not available for the financial contributors of the individual studies. S.A.E.P. and the meetings of the representatives of the combined authors of the four studies were financially supported by the EuDial working group. EuDial is an official working group of the European Renal Association-European Dialysis Transplant Association (ERA-EDTA, http://era-edta.org/eudial/European_Dialysis_Working_Group.html). No industry funding was received for any part of or activity related to the present analysis.; The Turkish HDF study was supported by European Nephrology and Dialysis Institute with an unrestricted grant. The study was performed in Fresenius Medical Care haemodialysis clinics in Turkey. ESHOL was supported by The Catalan Society of Nephrology and by grants from Fresenius Medical Care and Gambro through the Catalan Society of Nephrology. The CONTRAST study was supported by a grant from the Dutch Kidney Foundation (Nierstichting Nederland Grant C02.2019), and unrestricted grants from Fresenius Medical Care, Netherlands, and Gambro Lundia AB, Sweden. Additional support was received from the Dr E.E. Twiss Fund, Roche Netherlands, the International Society of Nephrology/Baxter Extramural Grant Program, and the Netherlands Organization for Health Research and Development (ZONMw Grant 170882802). The French HDF study was supported by a national grant from the Health Ministry (Programme Hospitalier de Recherche Clinique, PHRC) as a means to improve care and outcome of elderly chronic disease patients.

Published
2017
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32. The effect of natriuretic C-type peptide and its change over time on mortality in patients on haemodialysis or haemodiafiltration.

Author

Zuijdewijn, Camiel L M de Roij van, Gastel, Lieke H A van, Wee, Piet M ter, Bots, Michiel L, Blankestijn, Peter J, Dorpel, Marinus A van den, Fouque, Denis, Nubé, Menso J, and Grooteman, Muriel P C

Subjects
HEMODIALYSIS patients, MORTALITY, CHRONIC kidney failure, CARDIOVASCULAR system, BRAIN natriuretic factor
Abstract

Background C-type natriuretic peptide (CNP) and its co-product N-terminal proCNP (NTproCNP) have been associated with beneficial effects on the cardiovascular system. In prevalent dialysis patients, however, a relation between NTproCNP and mortality has not yet been investigated. Furthermore, as a middle molecular weight substance, its concentration might be influenced by dialysis modality. Methods In a cohort of patients treated with haemodialysis (HD) or haemodiafiltration (HDF), levels of NTproCNP were measured at baseline and 6, 12, 24 and 36 months. The relation between serum NTproCNP and mortality and the relation between the 6-month rate of change of NTproCNP and mortality were analysed using Cox regression models. For the longitudinal analyses, linear mixed models were used. Results In total, 406 subjects were studied. The median baseline serum NTproCNP was 93 pmol/L and the median follow-up was 2.97 years. No relation between baseline NTproCNP or its rate of change over 6 months and mortality was found. NTproCNP levels remained stable in HD patients, whereas NTproCNP decreased significantly in HDF patients. The relative decline depended on the magnitude of the convection volume. Conclusions In our study, levels of NTproCNP appear strongly elevated in prevalent dialysis patients. Second, while NTproCNP remains unaltered in HD patients, its levels decline in individuals treated with HDF, with the decline dependent on the magnitude of the convection volume. Third, NTproCNP is not related to mortality in this population. Thus NTproCNP does not seem to be a useful marker for mortality risk in dialysis patients. [ABSTRACT FROM AUTHOR]

Published
2021
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33. Long-term clinical parameters after switching to nocturnal haemodialysis: a Dutch propensity-score-matched cohort study comparing patients on nocturnal haemodialysis with patients on three-times-a-week haemodialysis/haemodiafiltration

Author

Jansz, Thijs Thomas, primary, Özyilmaz, Akin, additional, Grooteman, Muriel P C, additional, Hoekstra, Tiny, additional, Romijn, Marieke, additional, Blankestijn, Peter J, additional, Bots, Michael L, additional, and van Jaarsveld, Brigit C, additional

Published
2018
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35. Long-term clinical parameters after switching to nocturnal haemodialysis : a Dutch propensity-score-matched cohort study comparing patients on nocturnal haemodialysis with patients on three-times-a-week haemodialysis/haemodiafiltration

Author

Jansz, Thijs Thomas, Özyilmaz, Akin, Grooteman, Muriel P C, Hoekstra, Tiny, Romijn, Marieke, Blankestijn, Peter J, Bots, Michael L, van Jaarsveld, Brigit C, Jansz, Thijs Thomas, Özyilmaz, Akin, Grooteman, Muriel P C, Hoekstra, Tiny, Romijn, Marieke, Blankestijn, Peter J, Bots, Michael L, and van Jaarsveld, Brigit C

Published
2018

36. Long-term clinical parameters after switching to nocturnal haemodialysis: a Dutch propensity-score-matched cohort study comparing patients on nocturnal haemodialysis with patients on three-times-a-week haemodialysis/haemodiafiltration

Author

Nefro Vasculaire Geneeskunde, MS Nefrologie, Circulatory Health, Cardiovasculaire Epi Team 5, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Jansz, Thijs Thomas, Özyilmaz, Akin, Grooteman, Muriel P C, Hoekstra, Tiny, Romijn, Marieke, Blankestijn, Peter J, Bots, Michael L, van Jaarsveld, Brigit C, Nefro Vasculaire Geneeskunde, MS Nefrologie, Circulatory Health, Cardiovasculaire Epi Team 5, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Jansz, Thijs Thomas, Özyilmaz, Akin, Grooteman, Muriel P C, Hoekstra, Tiny, Romijn, Marieke, Blankestijn, Peter J, Bots, Michael L, and van Jaarsveld, Brigit C

Published
2018

38. Corrigendum

Author

van Loon, Ismay, primary, Hamaker, Marije E, additional, Boereboom, Franciscus T J, additional, Grooteman, Muriel P C, additional, Blankestijn, Peter J, additional, van den Dorpel, Rene M A, additional, Nubé, Menso J, additional, Ter Wee, Piet M, additional, Verhaar, Marianne C, additional, and Bots, Michiel L, additional

Published
2017
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39. Achieving high convection volumes in postdilution online hemodiafiltration : a prospective multicenter study

Author

de Roij van Zuijdewijn, Camiel L M, Chapdelaine, Isabelle, Nubé, Menso J., Blankestijn, Peter J, Bots, Michiel L, Konings, Constantijn J A M, Kremer Hovinga, Ton K, Molenaar, Femke M, van der Weerd, Neelke C., Grooteman, Muriel P C, de Roij van Zuijdewijn, Camiel L M, Chapdelaine, Isabelle, Nubé, Menso J., Blankestijn, Peter J, Bots, Michiel L, Konings, Constantijn J A M, Kremer Hovinga, Ton K, Molenaar, Femke M, van der Weerd, Neelke C., and Grooteman, Muriel P C

Published
2017

40. Quality of life as indicator of poor outcome in hemodialysis : relation with mortality in different age groups

Author

van Loon, I N, Bots, M L, Boereboom, Frans T J, Grooteman, Muriel P C, Blankestijn, P J, van den Dorpel, Marinus A., Nubé, Menso J., ter Wee, Pieter M., Verhaar, M C, Hamaker, M. E., van Loon, I N, Bots, M L, Boereboom, Frans T J, Grooteman, Muriel P C, Blankestijn, P J, van den Dorpel, Marinus A., Nubé, Menso J., ter Wee, Pieter M., Verhaar, M C, and Hamaker, M. E.

Published
2017

41. Achieving high convection volumes in postdilution online hemodiafiltration: a prospective multicenter study

Author

Nefro Vasculaire Geneeskunde, MS Nefrologie, Circulatory Health, Cardiovasculaire Epi Team 5, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, de Roij van Zuijdewijn, Camiel L M, Chapdelaine, Isabelle, Nubé, Menso J., Blankestijn, Peter J, Bots, Michiel L, Konings, Constantijn J A M, Kremer Hovinga, Ton K, Molenaar, Femke M, van der Weerd, Neelke C., Grooteman, Muriel P C, Nefro Vasculaire Geneeskunde, MS Nefrologie, Circulatory Health, Cardiovasculaire Epi Team 5, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, de Roij van Zuijdewijn, Camiel L M, Chapdelaine, Isabelle, Nubé, Menso J., Blankestijn, Peter J, Bots, Michiel L, Konings, Constantijn J A M, Kremer Hovinga, Ton K, Molenaar, Femke M, van der Weerd, Neelke C., and Grooteman, Muriel P C

Published
2017

42. Quality of life as indicator of poor outcome in hemodialysis: relation with mortality in different age groups

Author

Unit Opleiding Aios, Cardiovasculaire Epi Team 5, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, MS Nefrologie, Nefro Vasculaire Geneeskunde, Regenerative Medicine and Stem Cells, van Loon, I N, Bots, M L, Boereboom, Frans T J, Grooteman, Muriel P C, Blankestijn, P J, van den Dorpel, Marinus A., Nubé, Menso J., ter Wee, Pieter M., Verhaar, M C, Hamaker, M. E., Unit Opleiding Aios, Cardiovasculaire Epi Team 5, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, MS Nefrologie, Nefro Vasculaire Geneeskunde, Regenerative Medicine and Stem Cells, van Loon, I N, Bots, M L, Boereboom, Frans T J, Grooteman, Muriel P C, Blankestijn, P J, van den Dorpel, Marinus A., Nubé, Menso J., ter Wee, Pieter M., Verhaar, M C, and Hamaker, M. E.

Published
2017

43. Mortality reduction by post-dilution online-haemodiafiltration: A cause-specific analysis

Author

Cardiovasculaire Epi Team 5, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Circulatory Health, MS Nefrologie, MS CGO, MS Medische Oncologie, Cancer, Projectafdeling VCI, Secretariaat en overig CTC, AIOS Anesthesiologie, Nubé, Menso J., Peters, Sanne A E, Blankestijn, Peter J., Canaud, Bernard, Davenport, Andrew, Grooteman, Muriel P C, Asci, Gulay, Locatelli, Francesco, Maduell, Francisco, Morena, Marion, Ok, Ercan, Torres, Ferran, Bots, Michiel L., Moreso, Francesc, Pons, Mercedes, Ramos, Rosa, Mora-Macià, Josep, Carreras, Jordi, Soler, Jordi, Campistol, Josep M., Martinez-Castelao, Alberto, Insensé, B., Perez, C., Feliz, T., Barbetta, M., Soto, C., Mora, J., Juan, A., Ibrik, O., Foraster, A., Nin, J., Fernández, A., Arruche, M., Sánchez, C., Vidiella, J., Barbosa, F., Chiné, M., Hurtado, S., Llibre, J., Ruiz, A., Serra, M., Salvó, M., Poyuelo, T., Maduell, F., Carrera, M., Fontseré, N., Arias, M., Merín, A., Ribera, L., Galceran, J. M., Mòdol, J., Moliner, E., Ramirez, A., Aguilera, J., Alvarez, M., De La Torre, B., Molera, M., Casellas, J., Martín, G., Andres, E., Coll, E., Valles, M., Martínez, C., Castellote, E., Casals, J. M., Gabàs, J., Romero, M., Martinez-Castelao, A., Fulladosa, X., Ramirez-Arellano, M., Fulquet, M., Pelegrí, A., El Manouari, M., Ramos, N., Bartolomé, J., Sans, R., Fernández, E., Sarró, F., Compte, T., Marco, F., Mauri, R., Bronsoms, J., Arnaiz, J. A., Beleta, H., Pejenaute, A., Ríos, J., Lara, J., Ter Wee, P. M., Van Den Dorpel, M. A., Dorval, M., Lévesque, R., Koopman, M. G., Konings, C. J A M, Haanstra, W. P., Kooistra, M., Van Jaarsveld, B., Noordzij, T., Feith, G. W., Peltenburg, H. G., Van Buren, M., Offerman, J. J G, Hoogeveen, E. K., De Heer, F., Van De Ven, P. J., Kremer Hovinga, T. K., Bax, W. A., Groeneveld, J. O., Lavrijssen, A. T J, Schrander-Van Der Meer, A. M., Reichert, L. J M, Huussen, J., Rensma, P. L., Schrama, Y., Van Hamersvelt, H. W., Boer, W. H., Van Kuijk, W. H., Vervloet, M. G., Wauters, I. M P M J, Sekse, I., Toz, Huseyin, Ok, Ebru Sevinc, Kircelli, Fatih, Yilmaz, Mumtaz, Hur, Ender, Demirci, Meltem Sezis, Demirci, Cenk, Duman, Soner, Basci, Ali, Adam, Siddig Momin, Isik, Ismet Onder, Zengin, Murat, Suleymanlar, Gultekin, Yilmaz, Mehmet Emin, Ergin, Mehmet Ozkahya Pinar, Sagdic, Alfert, Kayali, Erkan, Boydak, Can, Colak, Taskin, Caliskan, Sihli, Kaplan, Hakan, Ulas, Hasibe, Kirbiyik, Sait, Berktas, Hakan, Dilbaz, Necati, Cristol, Jean Paul, Leray-Moragues, Hélène, Chenine, Leïla, Picot, Marie Christine, Jaussent, Audrey, Belloc, Claire, Lagarrigue, Mélodie, Chalabi, Lotfi, Debure, Alain, Ouziala, Messaoud, Lefevre, Jean Jacques, Thibaudin, Damien, Mohey, Hesham, Broyet, Christian, Afiani, Aida, Serveaux, Marie Odile, Patrier, Laure, Maurice, François, Rivory, Jean Pierre, Nicoud, Philippe, Durand, Claude, Normand, Michel, Seigneuric, Bruno, Magnant, Eric, Azzouz, Lynda, Islam, Mohamed Shariful, Vido, Sandor, Nzeyimana, Hilaire, Simonin, Danièle, Azymah, Yamina, Farah, Ibrahim, Coindre, Jean Philippe, Puyoo, Olivier, Chabannier, Marie Hélène, Ibos, Richard, Rouleau, Fabienne, Vela, Carlos, Joule, Josiane, Combarnous, François, Turc-Baron, Cécile, Ducret, Francis, Pointet, Philippe, Rey, Isabelle, Potier, Jacky, Bendini, Jean Christophe, Perrin, Franck, Kunz, Kristian, Lefrancois, Gaëlle, Colin, Angélique, Parahy, Sophie, Dancea, Irima, Coupel, Stéphanie, Testa, Angelo, Brunet, Philippe, Lebrun, Gaétan, Jaubert, Dominique, Delcroix, Catherine, Lavainne, Frédéric, Lefebvre, Anne, Guillodo, Marie Paule, Le Grignou, Dominique, Djema, Assia, Maaz, Mehadji, Chiron, Sylvie, Hoffmann, Maxime, Depraetre, Pascale, Haddj-Elmrabet, Atman, Joyeux, Véronique, Fleury, Dominique, Vrigneaud, Laurence, Lemaitre, Vincent, Aguilera, Didier, Guerraoui, Abdallah, Cremault, Alain, Laradi, Achour, Babinet, Francois, Cardiovasculaire Epi Team 5, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Circulatory Health, MS Nefrologie, MS CGO, MS Medische Oncologie, Cancer, Projectafdeling VCI, Secretariaat en overig CTC, AIOS Anesthesiologie, Nubé, Menso J., Peters, Sanne A E, Blankestijn, Peter J., Canaud, Bernard, Davenport, Andrew, Grooteman, Muriel P C, Asci, Gulay, Locatelli, Francesco, Maduell, Francisco, Morena, Marion, Ok, Ercan, Torres, Ferran, Bots, Michiel L., Moreso, Francesc, Pons, Mercedes, Ramos, Rosa, Mora-Macià, Josep, Carreras, Jordi, Soler, Jordi, Campistol, Josep M., Martinez-Castelao, Alberto, Insensé, B., Perez, C., Feliz, T., Barbetta, M., Soto, C., Mora, J., Juan, A., Ibrik, O., Foraster, A., Nin, J., Fernández, A., Arruche, M., Sánchez, C., Vidiella, J., Barbosa, F., Chiné, M., Hurtado, S., Llibre, J., Ruiz, A., Serra, M., Salvó, M., Poyuelo, T., Maduell, F., Carrera, M., Fontseré, N., Arias, M., Merín, A., Ribera, L., Galceran, J. M., Mòdol, J., Moliner, E., Ramirez, A., Aguilera, J., Alvarez, M., De La Torre, B., Molera, M., Casellas, J., Martín, G., Andres, E., Coll, E., Valles, M., Martínez, C., Castellote, E., Casals, J. M., Gabàs, J., Romero, M., Martinez-Castelao, A., Fulladosa, X., Ramirez-Arellano, M., Fulquet, M., Pelegrí, A., El Manouari, M., Ramos, N., Bartolomé, J., Sans, R., Fernández, E., Sarró, F., Compte, T., Marco, F., Mauri, R., Bronsoms, J., Arnaiz, J. A., Beleta, H., Pejenaute, A., Ríos, J., Lara, J., Ter Wee, P. M., Van Den Dorpel, M. A., Dorval, M., Lévesque, R., Koopman, M. G., Konings, C. J A M, Haanstra, W. P., Kooistra, M., Van Jaarsveld, B., Noordzij, T., Feith, G. W., Peltenburg, H. G., Van Buren, M., Offerman, J. J G, Hoogeveen, E. K., De Heer, F., Van De Ven, P. J., Kremer Hovinga, T. K., Bax, W. A., Groeneveld, J. O., Lavrijssen, A. T J, Schrander-Van Der Meer, A. M., Reichert, L. J M, Huussen, J., Rensma, P. L., Schrama, Y., Van Hamersvelt, H. W., Boer, W. H., Van Kuijk, W. H., Vervloet, M. G., Wauters, I. M P M J, Sekse, I., Toz, Huseyin, Ok, Ebru Sevinc, Kircelli, Fatih, Yilmaz, Mumtaz, Hur, Ender, Demirci, Meltem Sezis, Demirci, Cenk, Duman, Soner, Basci, Ali, Adam, Siddig Momin, Isik, Ismet Onder, Zengin, Murat, Suleymanlar, Gultekin, Yilmaz, Mehmet Emin, Ergin, Mehmet Ozkahya Pinar, Sagdic, Alfert, Kayali, Erkan, Boydak, Can, Colak, Taskin, Caliskan, Sihli, Kaplan, Hakan, Ulas, Hasibe, Kirbiyik, Sait, Berktas, Hakan, Dilbaz, Necati, Cristol, Jean Paul, Leray-Moragues, Hélène, Chenine, Leïla, Picot, Marie Christine, Jaussent, Audrey, Belloc, Claire, Lagarrigue, Mélodie, Chalabi, Lotfi, Debure, Alain, Ouziala, Messaoud, Lefevre, Jean Jacques, Thibaudin, Damien, Mohey, Hesham, Broyet, Christian, Afiani, Aida, Serveaux, Marie Odile, Patrier, Laure, Maurice, François, Rivory, Jean Pierre, Nicoud, Philippe, Durand, Claude, Normand, Michel, Seigneuric, Bruno, Magnant, Eric, Azzouz, Lynda, Islam, Mohamed Shariful, Vido, Sandor, Nzeyimana, Hilaire, Simonin, Danièle, Azymah, Yamina, Farah, Ibrahim, Coindre, Jean Philippe, Puyoo, Olivier, Chabannier, Marie Hélène, Ibos, Richard, Rouleau, Fabienne, Vela, Carlos, Joule, Josiane, Combarnous, François, Turc-Baron, Cécile, Ducret, Francis, Pointet, Philippe, Rey, Isabelle, Potier, Jacky, Bendini, Jean Christophe, Perrin, Franck, Kunz, Kristian, Lefrancois, Gaëlle, Colin, Angélique, Parahy, Sophie, Dancea, Irima, Coupel, Stéphanie, Testa, Angelo, Brunet, Philippe, Lebrun, Gaétan, Jaubert, Dominique, Delcroix, Catherine, Lavainne, Frédéric, Lefebvre, Anne, Guillodo, Marie Paule, Le Grignou, Dominique, Djema, Assia, Maaz, Mehadji, Chiron, Sylvie, Hoffmann, Maxime, Depraetre, Pascale, Haddj-Elmrabet, Atman, Joyeux, Véronique, Fleury, Dominique, Vrigneaud, Laurence, Lemaitre, Vincent, Aguilera, Didier, Guerraoui, Abdallah, Cremault, Alain, Laradi, Achour, and Babinet, Francois

Published
2017

44. Achieving high convection volumes in postdilution online hemodiafiltration: a prospective multicenter study

Author

de Roij van Zuijdewijn, Camiel L M, primary, Chapdelaine, Isabelle, additional, Nubé, Menso J, additional, Blankestijn, Peter J, additional, Bots, Michiel L, additional, Konings, Constantijn J A M, additional, Kremer Hovinga, Ton K, additional, Molenaar, Femke M, additional, van der Weerd, Neelke C, additional, and Grooteman, Muriel P C, additional

Published
2017
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45. Haemodiafiltration and mortality in end-stage kidney disease patients : a pooled individual participant data analysis from four randomized controlled trials

Author

Peters, Sanne A. E., Bots, Michiel L., Canaud, Bernard, Davenport, Andrew, Grooteman, Muriel P. C., Kircelli, Fatih, Locatelli, Francesco, Maduell, Francisco, Morena, Marion, Nube, Menso J., Ok, Ercan, Torres, Ferran, Woodward, Mark, Blankestijn, Peter J., Peters, Sanne A. E., Bots, Michiel L., Canaud, Bernard, Davenport, Andrew, Grooteman, Muriel P. C., Kircelli, Fatih, Locatelli, Francesco, Maduell, Francisco, Morena, Marion, Nube, Menso J., Ok, Ercan, Torres, Ferran, Woodward, Mark, and Blankestijn, Peter J.

Published
2016

46. Higher convection volume exchange with online hemodiafiltration is associated with survival advantage for dialysis patients : the effect of adjustment for body size

Author

Davenport, Andrew, Peters, Sanne A E, Bots, Michiel L., Canaud, Bernard, Grooteman, Muriel P C, Asci, Gulay, Locatelli, Francesco, Maduell, Francisco, Morena, Marion, Nubé, Menso J., Ok, Ercan, Torres, Ferran, Woodward, Mark, Blankestijn, Peter J., Davenport, Andrew, Peters, Sanne A E, Bots, Michiel L., Canaud, Bernard, Grooteman, Muriel P C, Asci, Gulay, Locatelli, Francesco, Maduell, Francisco, Morena, Marion, Nubé, Menso J., Ok, Ercan, Torres, Ferran, Woodward, Mark, and Blankestijn, Peter J.

Published
2016

47. Haemodiafiltration and mortality in end-stage kidney disease patients: a pooled individual participant data analysis from four randomized controlled trials

Author

Cardiovasculaire Epi Team 5, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Circulatory Health, MS Nefrologie, Peters, Sanne A. E., Bots, Michiel L., Canaud, Bernard, Davenport, Andrew, Grooteman, Muriel P. C., Kircelli, Fatih, Locatelli, Francesco, Maduell, Francisco, Morena, Marion, Nube, Menso J., Ok, Ercan, Torres, Ferran, Woodward, Mark, Blankestijn, Peter J., Cardiovasculaire Epi Team 5, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Circulatory Health, MS Nefrologie, Peters, Sanne A. E., Bots, Michiel L., Canaud, Bernard, Davenport, Andrew, Grooteman, Muriel P. C., Kircelli, Fatih, Locatelli, Francesco, Maduell, Francisco, Morena, Marion, Nube, Menso J., Ok, Ercan, Torres, Ferran, Woodward, Mark, and Blankestijn, Peter J.

Published
2016

48. Higher convection volume exchange with online hemodiafiltration is associated with survival advantage for dialysis patients: the effect of adjustment for body size

Author

Cardiovasculaire Epi Team 5, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Davenport, Andrew, Peters, Sanne A E, Bots, Michiel L., Canaud, Bernard, Grooteman, Muriel P C, Asci, Gulay, Locatelli, Francesco, Maduell, Francisco, Morena, Marion, Nubé, Menso J., Ok, Ercan, Torres, Ferran, Woodward, Mark, Blankestijn, Peter J., Cardiovasculaire Epi Team 5, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Davenport, Andrew, Peters, Sanne A E, Bots, Michiel L., Canaud, Bernard, Grooteman, Muriel P C, Asci, Gulay, Locatelli, Francesco, Maduell, Francisco, Morena, Marion, Nubé, Menso J., Ok, Ercan, Torres, Ferran, Woodward, Mark, and Blankestijn, Peter J.

Published
2016

50. Optimization of the convection volume in online post-dilution haemodiafiltration : practical and technical issues

Author

Chapdelaine, Isabelle, de Roij van Zuijdewijn, Camiel L M, Mostovaya, Ira M, Lévesque, Renée, Davenport, Andrew, Blankestijn, P J, Wanner, Christoph, Nubé, Menso J, Grooteman, Muriel P C, Davenport, A, Basile, C, Locatelli, F, Maduell, F, Mitra, S, Ronco, C, Shroff, R, Tattersall, J, Wanner, C, EUDIAL Group, Chapdelaine, Isabelle, de Roij van Zuijdewijn, Camiel L M, Mostovaya, Ira M, Lévesque, Renée, Davenport, Andrew, Blankestijn, P J, Wanner, Christoph, Nubé, Menso J, Grooteman, Muriel P C, Davenport, A, Basile, C, Locatelli, F, Maduell, F, Mitra, S, Ronco, C, Shroff, R, Tattersall, J, Wanner, C, and EUDIAL Group

Published
2015

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