26 results on '"Groot, Joris R de"'
Search Results
2. Design of the Dutch multicentre study on opportunistic screening of geriatric patients for atrial fibrillation using a smartphone PPG app: the Dutch-GERAF study
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Zwart, L.A.R., Spruit, J.R., Hemels, M.E.W., Groot, Joris R. de, Pisters, R., Riezebos, Robert K., Jansen, Rene W. M. M., Zwart, L.A.R., Spruit, J.R., Hemels, M.E.W., Groot, Joris R. de, Pisters, R., Riezebos, Robert K., and Jansen, Rene W. M. M.
- Abstract
Contains fulltext : 305934.pdf (Publisher’s version ) (Open Access)
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- 2024
3. Oral anticoagulation in device-detected atrial fibrillation: effects of age, sex, cardiovascular comorbidities, and kidney function on outcomes in the NOAH-AFNET 6 trial.
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Lip, Gregory Y H, Nikorowitsch, Julius, Sehner, Susanne, Becher, Nina, Bertaglia, Emanuele, Blomstrom-Lundqvist, Carina, Brandes, Axel, Beuger, Vincent, Calvert, Melanie, Camm, A John, Chlouverakis, Gregory, Dan, Gheorghe-Andrei, Dichtl, Wolfgang, Diener, Hans Christoph, Fierenz, Alexander, Goette, Andreas, Groot, Joris R de, Hermans, Astrid, Lubinski, Andrzej, and Marijon, Eloi
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ATRIAL fibrillation ,KIDNEY physiology ,HEART failure ,ANTICOAGULANTS ,TRANSIENT ischemic attack ,ARTIFICIAL implants ,PATIENT self-monitoring - Abstract
The article discusses the findings of a study on the effects of oral anticoagulation in patients with device-detected atrial fibrillation (DDAF) without ECG-documented atrial fibrillation (AF). The study analyzed data from 2534 patients and compared outcomes and the effect of anticoagulation in patients with different risk factors. The results showed that anticoagulation did not appear to be more effective in patients with a high risk score, and the rate of stroke was low in patients without anticoagulation. The study suggests the need for new methods to identify high-risk patients who may benefit from anticoagulation. The article also provides information about financial disclosures and funding sources related to the authors of the study. [Extracted from the article]
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- 2024
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4. Anticoagulation with edoxaban in patients with long atrial high-rate episodes ≥24 h.
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Becher, Nina, Toennis, Tobias, Bertaglia, Emanuele, Blomström-Lundqvist, Carina, Brandes, Axel, Cabanelas, Nuno, Calvert, Melanie, Camm, A John, Chlouverakis, Gregory, Dan, Gheorghe-Andrei, Dichtl, Wolfgang, Diener, Hans Christoph, Fierenz, Alexander, Goette, Andreas, Groot, Joris R de, Hermans, Astrid N L, Lip, Gregory Y H, Lubinski, Andrzej, Marijon, Eloi, and Merkely, Béla
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DISEASE risk factors ,EDOXABAN ,ATRIAL fibrillation ,ORAL medication ,ANTICOAGULANTS ,P-waves (Electrocardiography) - Abstract
Background and Aims Patients with long atrial high-rate episodes (AHREs) ≥24 h and stroke risk factors are often treated with anticoagulation for stroke prevention. Anticoagulation has never been compared with no anticoagulation in these patients. Methods This secondary pre-specified analysis of the Non-vitamin K antagonist Oral anticoagulants in patients with Atrial High-rate episodes (NOAH-AFNET 6) trial examined interactions between AHRE duration at baseline and anticoagulation with edoxaban compared with placebo in patients with AHRE and stroke risk factors. The primary efficacy outcome was a composite of stroke, systemic embolism, or cardiovascular death. The safety outcome was a composite of major bleeding and death. Key secondary outcomes were components of these outcomes and electrocardiogram (ECG)-diagnosed atrial fibrillation. Results Median follow-up of 2389 patients with core lab-verified AHRE was 1.8 years. AHRE ≥24 h were present at baseline in 259/2389 patients (11%, 78 ± 7 years old, 28% women, CHA2DS2-VASc 4). Clinical characteristics were not different from patients with shorter AHRE. The primary outcome occurred in 9/132 patients with AHRE ≥24 h (4.3%/patient-year, 2 strokes) treated with anticoagulation and in 14/127 patients treated with placebo (6.9%/patient-year, 2 strokes). Atrial high-rate episode duration did not interact with the efficacy (P -interaction =.65) or safety (P -interaction =.98) of anticoagulation. Analyses including AHRE as a continuous parameter confirmed this. Patients with AHRE ≥24 h developed more ECG-diagnosed atrial fibrillation (17.0%/patient-year) than patients with shorter AHRE (8.2%/patient-year; P <.001). Conclusions This hypothesis-generating analysis does not find an interaction between AHRE duration and anticoagulation therapy in patients with device-detected AHRE and stroke risk factors. Further research is needed to identify patients with long AHRE at high stroke risk. [ABSTRACT FROM AUTHOR]
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- 2024
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5. A cross-sectional nationwide survey of guideline based syncope units in the Netherlands: the SU-19 score—a novel validation for best practices.
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Zanten, Steven van, Jong, Jelle S Y de, Scheffer, Mike G, Kaal, Evert C A, Groot, Joris R de, and Lange, Frederik J de
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Aims We aimed to identify all syncope units (SUs) in the Netherlands and assess the extent to which these SUs fulfil the essential requirements outlined by the consensus statements of the European Heart Rhythm Association and the European Society of Cardiology syncope guidelines. For this, we developed the SU-19 score, a novel guideline based validation tool for best practice. Methods and results All outpatient clinics of cardiology, neurology, and internal medicine in the Netherlands were screened for presence of any form of structured specialized syncope care. If present, these were included as SUs and requested to complete a questionnaire regarding syncope care. We assessed all SUs using the SU-19 score regarding structure (3 points), available tests (12 points), and initial evaluation (4 points). Twenty SUs were identified in the Netherlands, both academic (5/20) and non-academic hospitals (15/20), 17/20 reported multidisciplinary involvement during initial evaluation. In 19/20, neurology, cardiology, or both were responsible for the syncope management. Non-physicians were involved performing the head-up tilt test (44%) and initial evaluation (40%). The mean SU-19 score was 18.0 ± 1.1, 45% achieved the maximum score of 19 points. Variations were observed in protocols for active standing test, carotid sinus massage, and head-up tilt test. Conclusion There is a network of 20 SUs in the Netherlands. Forty-five per cent fully met the SU-19 score (mean 18.0 ± 1.1). Slight variety existed in protocols for autonomic function tests. Neurology and cardiology were mostly involved in syncope management. Non-physicians play an important role in syncope care. [ABSTRACT FROM AUTHOR]
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- 2024
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6. The influence of atrial high-rate episodes on stroke and cardiovascular death: an update.
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Toennis, Tobias, Bertaglia, Emanuele, Brandes, Axel, Dichtl, Wolfgang, Fluschnik, Nina, Groot, Joris R de, Marijon, Eloi, Mont, Lluis, Lundqvist, Carina Blomström, Cabanelas, Nuno, Dan, G Andrei, Lubinski, Andrzej, Merkely, Béla, Rajappan, Kim, Sarkozy, Andrea, Velchev, Vasil, Wichterle, Dan, and Kirchhof, Paulus
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Atrial high-rate episodes (AHRE) are atrial tachyarrhythmias detected by continuous rhythm monitoring by pacemakers, defibrillators, or implantable cardiac monitors. Atrial high-rate episodes occur in 10–30% of elderly patients without atrial fibrillation. However, it remains unclear whether the presence of these arrhythmias has therapeutic consequences. The presence of AHRE increases the risk of stroke compared with patients without AHRE. Oral anticoagulation would have the potential to reduce the risk of stroke in patients with AHRE but is also associated with a rate of major bleeding of ∼2%/year. The stroke rate in patients with AHRE appears to be lower than the stroke rate in patients with atrial fibrillation. Wearables like smart-watches will increase the absolute number of patients in whom atrial arrhythmias are detected. It remains unclear whether anticoagulation is effective and, equally important, safe in patients with AHRE. Two randomized clinical trials, NOAH-AFNET6 and ARTESiA, are expected to report soon. They will provide much-needed information on the efficacy and safety of oral anticoagulation in patients with AHRE. [ABSTRACT FROM AUTHOR]
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- 2023
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7. Device-related complications in subcutaneous versus transvenous ICD: a secondary analysis of the PRAETORIAN trial.
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Knops, Reinoud E, Pepplinkhuizen, Shari, Delnoy, Peter Paul H M, Boersma, Lucas V A, Kuschyk, Juergen, El-Chami, Mikhael F, Bonnemeier, Hendrik, Behr, Elijah R, Brouwer, Tom F, Kaab, Stefan, Mittal, Suneet, Quast, Anne-Floor B E, van der Stuijt, Willeke, Smeding, Lonneke, Veld, Jolien A de, Tijssen, Jan G P, Bijsterveld, Nick R, Richter, Sergio, Brouwer, Marc A, and Groot, Joris R de
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SECONDARY analysis ,IMPLANTABLE cardioverter-defibrillators - Abstract
Background The subcutaneous implantable cardioverter-defibrillator (S-ICD) is developed to overcome lead-related complications and systemic infections, inherent to transvenous ICD (TV-ICD) therapy. The PRAETORIAN trial demonstrated that the S-ICD is non-inferior to the TV-ICD with regard to the combined primary endpoint of inappropriate shocks and complications. This prespecified secondary analysis evaluates all complications in the PRAETORIAN trial. Methods and results The PRAETORIAN trial is an international, multicentre, randomized trial in which 849 patients with an indication for ICD therapy were randomized to receive an S- ICD (N = 426) or TV-ICD (N = 423) and followed for a median of 49 months. Endpoints were device-related complications, lead-related complications, systemic infections, and the need for invasive interventions. Thirty-six device-related complications occurred in 31 patients in the S-ICD group of which bleedings were the most frequent. In the TV-ICD group, 49 complications occurred in 44 patients of which lead dysfunction was most frequent (HR: 0.69; P = 0.11). In both groups, half of all complications were within 30 days after implantation. Lead-related complications and systemic infections occurred significantly less in the S-ICD group compared with the TV-ICD group (P < 0.001, P = 0.03, respectively). Significantly more complications required invasive interventions in the TV-ICD group compared with the S-ICD group (8.3% vs. 4.3%, HR: 0.59; P = 0.047). Conclusion This secondary analysis shows that lead-related complications and systemic infections are more prevalent in the TV-ICD group compared with the S-ICD group. In addition, complications in the TV-ICD group were more severe as they required significantly more invasive interventions. This data contributes to shared decision-making in clinical practice. [ABSTRACT FROM AUTHOR]
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- 2022
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8. Diagnostic yield and accuracy in a tertiary referral syncope unit validating the ESC guideline on syncope: a prospective cohort study
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Jong, Jelle S.Y. de, Snijders Blok, Minou R., Thijs, Roland D., Harms, Mark P.M., Hemels, M.E.W., Groot, Joris R. de, Dijk, Nynke van, Lange, Frederik J. de, Jong, Jelle S.Y. de, Snijders Blok, Minou R., Thijs, Roland D., Harms, Mark P.M., Hemels, M.E.W., Groot, Joris R. de, Dijk, Nynke van, and Lange, Frederik J. de
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Contains fulltext : 234172.pdf (Publisher’s version ) (Open Access)
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- 2021
9. Diagnostic yield and accuracy in a tertiary referral syncope unit validating the ESC guideline on syncope: a prospective cohort study.
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Jong, Jelle S Y de, Blok, Minou R Snijders, Thijs, Roland D, Harms, Mark P M, Hemels, Martin E W, Groot, Joris R de, Dijk, Nynke van, Lange, Frederik J de, de Jong, Jelle S Y, de Groot, Joris R, van Dijk, Nynke, and de Lange, Frederik J
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SYNCOPE ,HOSPITAL emergency services ,ARTHRITIS Impact Measurement Scales ,MEDICAL referrals ,LONGITUDINAL method - Abstract
Aims: To assess in patients with transient loss of consciousness the diagnostic yield, accuracy, and safety of the structured approach as described in the ESC guidelines in a tertiary referral syncope unit.Methods and Results: Prospective cohort study including 264 consecutive patients (≥18 years) referred with at least one self-reported episode of transient loss of consciousness and presenting to the syncope unit between October 2012 and February 2015. The study consisted of three phases: history taking (Phase 1), autonomic function tests (AFTs) (Phase 2), and after 1.5-year follow-up with assessment by a multidisciplinary committee (Phase 3). Diagnostic yield was assessed after Phases 1 and 2. Empirical diagnostic accuracy was measured for diagnoses according to the ESC guidelines after Phase 3. The diagnostic yield after Phase 1 (history taking) was 94.7% (95% CI: 91.1-97.0%, 250/264 patients) and increased to 97.0% (93.9-98.6%, 256/264 patients) after Phase 2. The overall diagnostic accuracy (as established in Phase 3) of the Phases 1 and 2 diagnoses was 90.6% (95% CI: 86.2-93.8%, 232/256 patients). No life-threatening conditions were missed. Three patients died, two unrelated to the cause of transient loss of consciousness, and one whom remained undiagnosed.Conclusion: A clinical work-up at a tertiary syncope unit using the ESC guidelines has a high diagnostic yield, accuracy, and safety. History taking (Phase 1) is the most important diagnostic tool. Autonomic function tests never changed the Phase 1 diagnosis but helped to increase the certainty of the Phase 1 diagnosis in many patients and yield additional diagnoses in patients who remained undiagnosed after Phase 1. Diagnoses were inaccurate in 9.4%, but no serious conditions were missed. This is adequate for clinical practice. [ABSTRACT FROM AUTHOR]- Published
- 2021
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10. Complications in pulmonary vein isolation in the Netherlands Heart Registration differ with sex and ablation technique.
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Mol, Daniel, Houterman, Saskia, Balt, Jippe C, Bhagwandien, Rohit E, Blaauw, Yuri, Delnoy, Peter-Paul H, Driel, Vincent J van, Driessen, Antoine H, Folkeringa, Richard J, Hassink, Rutger J, Huysduynen, Bart Hooft van, Luermans, Justin G, Ouss, Alexandre J, Stevenhagen, Yorick J, Veghel, Dennis van, Westra, Sjoerd W, Jong, Jonas S de, Groot, Joris R de, Committee, the Netherlands Heart Registration Ablation Registration, and van Driel, Vincent J
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ATRIAL fibrillation diagnosis ,ATRIAL fibrillation ,CRYOSURGERY ,CATHETER ablation ,DISEASE relapse ,TREATMENT effectiveness ,PULMONARY veins ,ABLATION techniques - Abstract
Aims: Pulmonary vein isolation (PVI) has become a cornerstone of the invasive treatment of atrial fibrillation. Severe complications are reported in 1-3% of patients. This study aims to compare complications and follow-up outcome of PVI in patients with atrial fibrillation.Methods and Results: The data were extracted from the Netherlands Heart Registration. Procedural and follow-up outcomes in patients treated with conventional radiofrequency (C-RF), multielectrode phased RF (Ph-RF), or cryoballoon (CB) ablation from 2012 to 2017 were compared. Subgroup analysis was performed to identify variables associated with complications and repeat ablations. In total, 13 823 patients (69% male) were included. The reported complication incidence was 3.6%. Patients treated with C-RF developed more cardiac tamponades (C-RF 0.8% vs. Ph-RF 0.3% vs. CB 0.3%, P ≤ 0.001) and vascular complications (C-RF 1.7% vs. Ph-RF 1.2% vs. CB 1.3%, P ≤ 0.001). Ph-RF was associated with fewer bleeding complications (C-RF: 1.0% vs. Ph-RF: 0.4% vs. CB: 0.7%, P = 0.020). Phrenic nerve palsy mainly occurred in patients treated with CB (C-RF: 0.1% vs. Ph-RF: 0.2% vs. CB: 1.5%, P ≤ 0.001). In total, 18.4% of patients were referred for repeat ablation within 1 year. Female sex, age, and CHA2DS2-VASc were independent risk factors for cardiac tamponade and bleeding complications, with an adjusted OR for female patients of 2.97 (95% CI 1.98-4.45) and 2.02 (95% CI 1.03-4.00) respectively.Conclusion: The reported complication rate during PVI was low. Patients treated with C-RF ablation were more likely to develop cardiac tamponades and vascular complications. Female sex was associated with more cardiac tamponade and bleeding complications. [ABSTRACT FROM AUTHOR]- Published
- 2021
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11. Temporal patterns and short-term progression of paroxysmal atrial fibrillation: data from RACE V.
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With, Ruben R De, Erküner, Ömer, Rienstra, Michiel, Nguyen, Bao-Oanh, Körver, Frank W J, Linz, Dominik, Ten, Hugo Cate, Spronk, Henri, Kroon, Abraham A, Maass, Alexander H, Blaauw, Yuri, Tieleman, Robert G, Hemels, Martin E W, Groot, Joris R de, Elvan, Arif, Melis, Mirko de, Scheerder, Coert O S, Al-Jazairi, Meelad I H, Schotten, Ulrich, and Luermans, Justin G L M
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ATRIAL fibrillation diagnosis ,DISEASE progression ,RESEARCH ,CAROTID intima-media thickness ,RESEARCH methodology ,ARTHRITIS Impact Measurement Scales ,ATRIAL fibrillation ,ACQUISITION of data ,MEDICAL cooperation ,EVALUATION research ,COMPARATIVE studies ,MENTAL health surveys ,QUESTIONNAIRES ,CARDIAC pacemakers ,HEART failure - Abstract
Aims: Atrial fibrillation (AF) often starts as a paroxysmal self-terminating arrhythmia. Limited information is available on AF patterns and episode duration of paroxysmal AF. In paroxysmal AF patients, we longitudinally studied the temporal AF patterns, the association with clinical characteristics, and prevalence of AF progression.Methods and Results: In this interim analysis of the Reappraisal of AF: Interaction Between HyperCoagulability, Electrical Remodelling, and Vascular Destabilisation in the Progression of AF (RACE V) registry, 202 patients with paroxysmal AF were followed with continuous rhythm monitoring (implantable loop recorder or pacemaker) for 6 months. Mean age was 64 ± 9 years, 42% were women. Atrial fibrillation history was 2.1 (0.5-4.4) years, CHA2DS2-VASc 1.9 ± 1.3, 101 (50%) had hypertension, 69 (34%) heart failure. One-third had no AF during follow-up. Patients with long episodes (>12 hours) were often men with more comorbidities (heart failure, coronary artery disease, higher left ventricular mass). Patients with higher AF burden (>2.5%) were older with more comorbidities (worse renal function, higher calcium score, thicker intima media thickness). In 179 (89%) patients, 1-year rhythm follow-up was available. On a quarterly basis, average daily AF burden increased from 3.2% to 3.8%, 5.2%, and 6.1%. Compared to the first 6 months, 111 (62%) patients remained stable during the second 6 months, 39 (22%) showed progression to longer AF episodes, 8 (3%) developed persistent AF, and 29 (16%) patients showed AF regression.Conclusions: In paroxysmal AF, temporal patterns differ suggesting that paroxysmal AF is not one entity. Atrial fibrillation burden is low and determined by number of comorbidities. Atrial fibrillation progression occurred in a substantial number.Trial Registration Number: Clinicaltrials.gov identifier NCT02726698. [ABSTRACT FROM AUTHOR]- Published
- 2020
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12. Determinants of left atrium thrombi in scheduled cardioversion: an ENSURE-AF study analysis.
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Merino, Jose L, Lip, Gregory Y H, Heidbuchel, Hein, Cohen, Aron-Ariel, Caterina, Raffaele De, Groot, Joris R de, Ezekowitz, Michael D, Heuzey, Jean-Yves Le, Themistoclakis, Sakis, Jin, James, Melino, Michael, Winters, Shannon M, Merkely, Béla, Goette, Andreas, De Caterina, Raffaele, de Groot, Joris R, and Le Heuzey, Jean-Yves
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Aims: ENSURE-AF (NCT02072434) was the largest prospective randomized clinical trial of anticoagulation for cardioversion in atrial fibrillation (AF), which also provides the largest prospective dataset for transoesophageal echocardiography (TOE) prior to cardioversion. This ancillary analysis investigated determinants of TOE-detected left atrium thrombi (LAT) in patients scheduled for electrical cardioversion (ECV).Methods and Results: The ENSURE-AF multicentre PROBE evaluation trial compared edoxaban 60 mg once daily (QD) with enoxaparin/warfarin in 2199 subjects undergoing ECV of non-valvular AF. Patients were stratified by the use of TOE, anticoagulant experience, and selected edoxaban dose. Electrical cardioversion was cancelled or deferred when TOEdetected LAT. In total, 1183 subjects were stratified to the TOE arm and LAT was reported in 91 (8.2%). In univariate analysis, age ≥75 years (26.4% vs. 16.9%, P = 0.0308), lower weight (86.5 ± 15.0 vs. 90.7 ± 18.0 kg, P = 0.0309), lower creatinine clearance (80.1 ± 30.6 vs. 93.2 ± 33.9 mL/min, P = 0.0007), heart failure (59.3% vs. 43.0%, P = 0.0029), and diuretic treatment (53.9% vs. 40.1%, P = 0.0141) were more prevalent in the LAT group. Non-significant trends were seen for higher mean CHA2DS2-VASc score (3.0 ± 1.41 vs. 2.7 ± 1.48, P = 0.0571) and more prevalent anticoagulation use prior to enrolment (60.4% vs. 50.3%, P = 0.0795) in the LAT group. In logistic regression analysis, age (P = 0.0202) and heart failure (P = 0.0064) were independently associated with LAT.Conclusion: Elective ECV is commonly cancelled or deferred due to TOE-detected LAT in patients with non-valvular AF. Age ≥75 years and heart failure were associated with the presence of LAT. [ABSTRACT FROM AUTHOR]- Published
- 2019
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13. Atrial high-rate episodes: prevalence, stroke risk, implications for management, and clinical gaps in evidence.
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Bertaglia, Emanuele, Blank, Benjamin, Blomström-Lundqvist, Carina, Brandes, Axel, Cabanelas, Nuno, Dan, G -Andrei, Dichtl, Wolfgang, Goette, Andreas, Groot, Joris R de, Lubinski, Andrzej, Marijon, Eloi, Merkely, Béla, Mont, Lluis, Piorkowski, Christopher, Sarkozy, Andrea, Sulke, Neil, Vardas, Panos, Velchev, Vasil, Wichterle, Dan, and Kirchhof, Paulus
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Self-terminating atrial arrhythmias are commonly detected on continuous rhythm monitoring, e.g. by pacemakers or defibrillators. It is unclear whether the presence of these arrhythmias has therapeutic consequences. We sought to summarize evidence on the prevalence of atrial high-rate episodes (AHREs) and their impact on risk of stroke. We performed a comprehensive, tabulated review of published literature on the prevalence of AHRE. In patients with AHRE, but without atrial fibrillation (AF), we reviewed the stroke risk and the potential risk/benefit of oral anticoagulation. Atrial high-rate episodes are found in 10-30% of AF-free patients. Presence of AHRE slightly increases stroke risk (0.8% to 1%/year) compared with patients without AHRE. Atrial high-rate episode of longer duration (e.g. those >24 h) could be associated with a higher stroke risk. Oral anticoagulation has the potential to reduce stroke risk in patients with AHRE but is associated with a rate of major bleeding of 2%/year. Oral anticoagulation is not effective in patients with heart failure or survivors of a stroke without AF. It remains unclear whether anticoagulation is effective and safe in patients with AHRE. Atrial high-rate episodes are common and confer a slight increase in stroke risk. There is true equipoise on the best way to reduce stroke risk in patients with AHRE. Two ongoing trials (NOAH-AFNET 6 and ARTESiA) will provide much-needed information on the effectiveness and safety of oral anticoagulation using non-vitamin K antagonist oral anticoagulants in patients with AHRE. [ABSTRACT FROM AUTHOR]
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- 2019
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14. Burden of atrial high-rate episodes and risk of stroke: a systematic review.
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Uittenbogaart, Steven B, Lucassen, Wim A M, Etten-Jamaludin, Faridi S van, Groot, Joris R de, Weert, Henk C P M van, van Etten-Jamaludin, Faridi S, de Groot, Joris R, and van Weert, Henk C P M
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ATRIAL fibrillation ,STROKE ,SYSTEMATIC reviews ,PROPORTIONAL hazards models - Abstract
Aims: Atrial fibrillation (AF) patients have increased risk of stroke. In paroxysmal AF, the combination of duration and frequency of episodes defines AF burden. In patients with cardiac implantable electronic devices (CIEDs), atrial high-rate episodes (AHREs) can be monitored continuously and are considered as a proxy for AF. This systematic review aims to determine the relationship between AF burden and risk of thrombo-embolic events (TBEs).Methods and results: We searched Medline, Embase, PubMed, and Cochrane Library databases and performed a review and meta-analysis. Eligible studies reported rhythm registration with specified AF burden and 3 months of follow-up for TBEs. Of the 8849 identified publications, 7 met the inclusion criteria. Of the 18 943 included patients, 215 (1.1%) patients developed a TBE. We detected only studies registering AHRE with a duration over 5 min detected by CIED. In a meta-analysis, patients with an AHRE burden over 6 min had an increased risk of TBE when compared with patients without AHRE, but this risk did not increase for an AHRE burden over 6 h [hazard ratio (HR) 1.82 vs. 1.78]. In a second meta-analysis, only patients with AHRE burden over 24 h had an increased risk for stroke (HR 3.2, 95% confidence interval 1.75-5.86), while patients with an AHRE burden shorter than 24 h did not.Conclusion: Patients with an AHRE burden over 6 min have an increased risk for stroke. A trend in which a higher AHRE burden leads to a higher risk for TBEs was observed but not substantiated due to heterogeneity and low numbers. [ABSTRACT FROM AUTHOR]- Published
- 2018
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15. Sudden cardiac death in adults with congenital heart disease: does QRS-complex fragmentation discriminate in structurally abnormal hearts?
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Vehmeijer, Jim T, Koyak, Zeliha, Bokma, Jouke P, Budts, Werner, Harris, Louise, Mulder, Barbara J M, Groot, Joris R de, and de Groot, Joris R
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Aims: Sudden cardiac death (SCD) causes a large portion of all mortality in adult congenital heart disease (ACHD) patients. However, identification of high-risk patients remains challenging. Fragmented QRS-complexes (fQRS) are a marker for SCD in patients with acquired heart disease but data in ACHD patients are lacking. We therefore aim to evaluate the prognostic value of fQRS for SCD in ACHD patients.Methods and results: From a multicentre cohort of 25 790 ACHD patients, we included tachyarrhythmic SCD cases (n = 147), and controls (n = 266) matched by age, gender, congenital defect and (surgical) intervention. fQRS was defined as ≥1 discontinuous deflection in narrow QRS-complexes, and ≥2 in wide QRS-complexes (>120 ms), in two contiguous ECG leads. We calculated odds ratios (OR) using univariable and multivariable conditional logistic regression models correcting for impaired systemic ventricular function, heart failure and QRS duration >120 ms. ECGs of 147 SCD cases (65% male, median age of death 34 years) and of 266 controls were assessed. fQRS was present in 51% of cases and 34% of controls (OR 2.0, P = 0.003). In multivariable analysis, fQRS was independently associated with SCD (OR 1.9, P = 0.01). The most common diagnose of SCD cases was tetralogy of Fallot (ToF, 34 cases). In ToF, fQRS was present in 71% of cases vs. 43% of controls (OR for SCD 2.8, P = 0.03).Conclusions: fQRS was independently associated with SCD in ACHD patients in a cohort of SCD patients and matched controls. fQRS may therefore contribute to the decision when evaluating ACHD patients for primary prevention of SCD. [ABSTRACT FROM AUTHOR]- Published
- 2018
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16. Cardiac diagnostic work-up of ischaemic stroke.
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Yang, Hayang, Nassif, Martina, Khairy, Paul, Groot, Joris R de, Roos, Yvo B W E M, Winter, Robbert J de, Mulder, Barbara J M, and Bouma, Berto J
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Cardioembolic sources account for 20-30% of ischaemic strokes and are important to identify considering their prognostic and therapeutic implications. During the past years, new developments have been made in the cardiac diagnostic evaluation and management of patients with ischaemic stroke, especially regarding strokes of unknown aetiology. These recent advances have had a major impact on our understanding of embolic strokes, their diagnostic work-up, and clinical management. Herein, we propose a cardiac diagnostic work-up scheme for patients with ischaemic stroke from definite cardioembolic sources and embolic strokes of undetermined source. [ABSTRACT FROM AUTHOR]
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- 2018
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17. IN-HOSPITAL ARRHYTHMIAS AFTER CONGENITAL HEART SURGERY FOR ADULTS: INCIDENCE AND RISK FACTORS
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Koyak, Zeliha, primary, Achterbergh, Roel C.A., additional, Groot, Joris R. de, additional, Berger, Felix, additional, Koolbergen, David R., additional, Hazekamp, Mark G., additional, Blom, Nico A., additional, Bouma, Berto J., additional, and Mulder, Barbara J. M, additional
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- 2013
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18. THE RISK OF SUDDEN CARDIAC DEATH IN ADULT CONGENITAL HEART DISEASE: IMPLICATIONS FOR IMPLANTABLE CARDIOVERTER DEFIBRILLATOR THERAPY
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Koyak, Zeliha, primary, Mulder, Barbara, additional, Zwinderman, Aeilko, additional, Harris, Louise, additional, Oechslin, Erwin, additional, Bouma, Berto, additional, Silversides, Candice, additional, Budts, Werner, additional, van Gelder, Isabelle, additional, and Groot, Joris R. de, additional
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- 2013
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19. On the Dutch Registry of catheter ablation of atrial fibrillation: Authors' reply.
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Mol, Daniel, Jong, Jonas S S G de, Groot, Joris R de, Committee, the co-authors and the Netherlands Heart Registration Ablation Registration, de Jong, Jonas S S G, de Groot, Joris R, all the co-authors and the Netherlands Heart Registration Ablation Registration Committee, and co-authors and the Netherlands Heart Registration Ablation Registration Committee
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- 2021
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20. Atrial Fibrosis and Conduction Slowing in the Left Atrial Appendage of Patients Undergoing Thoracoscopic Surgical Pulmonary Vein Isolation for Atrial Fibrillation
- Author
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Krul, Sébastien P.J., Berger, Wouter R., Smit, Nicoline W., Amersfoorth, Shirley C.M. van, Driessen, Antoine H.G., Boven, Wim Jan van, Fiolet, Jan W.T., Ginneken, Antoni C.G. van, Wal, Allard C. van der, Bakker, Jacques M.T. de, Coronel, Ruben, and Groot, Joris R. de
- Abstract
Atrial fibrosis is an important component of the arrhythmogenic substrate in patients with atrial fibrillation (AF). We studied the effect of interstitial fibrosis on conduction velocity (CV) in the left atrial appendage of patients with AF.
- Published
- 2015
- Full Text
- View/download PDF
21. The ICD for Primary Prevention in Patients With Inherited Cardiac Diseases
- Author
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Nordkamp, Louise R.A. Olde, Wilde, Arthur A.M., Tijssen, Jan G.P., Knops, Reinoud E., Dessel, Pascal F.H.M. van, and Groot, Joris R. de
- Abstract
Indications for prophylactic implantable cardioverter-defibrillator (ICD) therapy in patients with inherited cardiac diseases stem from observational studies and are uncertain. This study evaluates the efficacy and harm rate of ICD implantations for primary prevention compared with secondary prevention in inherited cardiac diseases.
- Published
- 2013
- Full Text
- View/download PDF
22. Sudden Cardiac Death in Adult Congenital Heart Disease
- Author
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Koyak, Zeliha, Harris, Louise, Groot, Joris R. de, Silversides, Candice K., Oechslin, Erwin N., Bouma, Berto J., Budts, Werner, Zwinderman, Aeilko H., Gelder, Isabelle C. Van, and Mulder, Barbara J.M.
- Abstract
Sudden cardiac death (SCD) is a major cause of mortality in adults with congenital heart disease (CHD). The aim of this study was to determine the adult CHD population at risk of SCD and the clinical parameters associated with SCD.
- Published
- 2012
- Full Text
- View/download PDF
23. Implantable Cardioverter-Defibrillators Have Reduced the Incidence of Resuscitation for Out-of-Hospital Cardiac Arrest Caused by Lethal Arrhythmias
- Author
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Hulleman, Michiel, Berdowski, Jocelyn, Groot, Joris R. de, Dessel, Pascal F.H.M. van, Borleffs, C. Jan Willem, Blom, Marieke T., Bardai, Abdenasser, Cock, Carel C. de, Tan, Hanno L., Tijssen, Jan G.P., and Koster, Rudolph W.
- Abstract
Over the last decades, a gradual decrease in ventricular fibrillation (VF) as initial recorded rhythm during resuscitation for out-of-hospital cardiac arrest (OHCA) has been noted. We sought to establish the contribution of implantable cardioverter-defibrillator (ICD) therapy to this decline.
- Published
- 2012
- Full Text
- View/download PDF
24. Implantable Cardioverter Defibrillator Therapy in Adults With Congenital Heart Disease
- Author
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Koyak, Zeliha, Groot, Joris R. de, Gelder, Isabelle C. Van, Bouma, Berto J., Dessel, Pascal F.H.M. van, Budts, Werner, van Erven, Lieselot, Dijk, Arie P.J. van, Wilde, Arthur A.M., Pieper, Petronella G., Sieswerda, Gertjan T., and Mulder, Barbara J.M.
- Abstract
The value of implantable cardioverter defibrillators (ICDs) in adults with congenital heart disease (CHD) is unknown. We investigated the long-term outcome after ICD implantation and developed a simple risk stratification score for ICD therapy.
- Published
- 2012
- Full Text
- View/download PDF
25. Thoracoscopic Video-Assisted Pulmonary Vein Antrum Isolation, Ganglionated Plexus Ablation, and Periprocedural Confirmation of Ablation Lesions
- Author
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Krul, Sébastien P.J., Driessen, Antoine H.G., Boven, Wim J. van, Linnenbank, André C., Geuzebroek, Guillaume S.C., Jackman, Warren M., Wilde, Arthur A.M., Bakker, Jacques M.T. de, and Groot, Joris R. de
- Abstract
Thoracoscopic pulmonary vein isolation (PVI) and ganglionated plexus ablation is a novel approach in the treatment of atrial fibrillation (AF). We hypothesize that meticulous electrophysiological confirmation of PVI results in fewer recurrences of AF during follow-up.
- Published
- 2011
- Full Text
- View/download PDF
26. Transient ST-segment elevation and coronary flow.
- Author
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Coronel, Ruben, Groot, Joris R. de, and Piek, Jan J.
- Published
- 2019
- Full Text
- View/download PDF
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