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1. Contributors

Author

Abzug, Mark J., primary, Acharya, Priyamvada, additional, Acosta, Anna M., additional, Ahmed, S. Sohail, additional, Amanna, Ian J., additional, Anderson, Annaliesa S., additional, Asturias, Edwin J., additional, Bachmann, Martin F., additional, Bahl, Sunil, additional, Bailey, Justin R., additional, Baker, Carol J., additional, Balfour, Henry H., additional, Baric, Ralph S., additional, Barnett, Elizabeth D., additional, Barrett, Alan D.T., additional, Belser, Jessica A., additional, Berzofsky, Jay A., additional, Bethony, Jeffrey M., additional, Brewer-Jensen, Paul D., additional, Bubak, Andrew N., additional, Burns, Cara C., additional, Caplan, Arthur L., additional, Cavaleri, Marco, additional, Chandran, Aruna, additional, Cherian, Thomas, additional, Clemens, John D., additional, Cochino, Emil, additional, Cohet, Catherine, additional, Cohn, Amanda, additional, Cortese, Margaret M., additional, Crowcroft, Natasha S., additional, Curtis, Nigel, additional, Damron, F. Heath, additional, Danchin, Margie, additional, Debbink, Kari, additional, Desai, Sachin N., additional, Davis, Emily H., additional, Decker, Michael D., additional, Denison, Mark R., additional, DeStefano, Frank, additional, Douglas, R. Gordon, additional, Dreher-Lesnick, Sheila M., additional, Eberhardt, Christiane S., additional, Edmunds, W. John, additional, Edwards, Caitlin E., additional, Edwards, Kathryn M., additional, Eggers, Rudolf, additional, Ellis, Ronald, additional, Erdman, Dean D., additional, Ertl, Hildegund C.J., additional, Estivariz, Concepcion F., additional, Fine, Paul E.M., additional, Finn, Theresa M., additional, Fisher, Allison M., additional, Fitzwater, Sean Patrick, additional, Freedman, Mark S., additional, Friede, Martin, additional, Friedlander, Arthur M., additional, Frumento, Nicole, additional, Fry, Alicia M., additional, Garçon, Nathalie, additional, Geris, Jennifer M., additional, Gershon, Anne A., additional, Gervier, Regis, additional, Gessner, Bradford D., additional, Gilbert, Peter B., additional, Gomez, Phillip Louis, additional, Ginsberg, Ann M., additional, Grabenstein, John D., additional, Graham, Rachel L., additional, Graham, Barney S., additional, Granoff, Dan M., additional, Gray, Gregory C., additional, Greenberg, David P., additional, Grohskopf, Lisa A., additional, Gruber, Marion F., additional, Guerena, Fernando B., additional, Havelange, Nicolas, additional, Halstead, Scott B., additional, Hanekom, Willem A., additional, Harrison, Lee H., additional, Hawn, Thomas R., additional, Haynes, Barton F., additional, Healy, C. Mary, additional, Hills, Susan L., additional, Hirabayashi, Kuniko, additional, Holmgren, Jan, additional, Hombach, Joachim M., additional, Hotez, Peter Jay, additional, Howe, Barbara J., additional, Hunegnaw, Ruth, additional, Izopet, Jacques, additional, Jamieson, Denise J., additional, Jansen, Kathrin, additional, Jarrahian, Courtney, additional, Johansen, Kari, additional, Kahn, Geoffrey D., additional, Karron, Ruth A., additional, Katz, Jacqueline M., additional, Kennedy, Richard B., additional, Broojerdi, Alireza Khadem, additional, Khetsuriani, Nino, additional, Khudyakov, Yury, additional, Klugman, Keith P., additional, Kocher, Jacob F., additional, Kollaritsch, Herwig, additional, Kotloff, Karen L., additional, Kozarsky, Phyllis E., additional, Kreimer, Aimée R., additional, Kroger, Andrew T., additional, Kwong, Peter D., additional, Lal, Manjari, additional, Levin, Myron J., additional, Levine, Myron M., additional, Lindesmith, Lisa C., additional, Lindstrand, Ann, additional, Ljungman, Per, additional, Lowy, Douglas R., additional, Lundgren, Anna, additional, Lydon, Patrick, additional, Macklin, Grace R., additional, Maeng, Hoyoung M., additional, Mahalingam, Ravi, additional, Malley, Richard, additional, Mallory, Michael L., additional, Marfin, Anthony A., additional, Markowitz, Lauri E., additional, Marshall, CDR Valerie, additional, McCollum, Andrea, additional, Meyer, Sarah, additional, McNamara, Lucy A., additional, Menning, Lisa, additional, Messacar, Kevin, additional, Miller, Mark A., additional, Milutinovic, Pavle, additional, Modlin, John F., additional, Monath, Thomas P., additional, Morabito, Kaitlyn M., additional, Moss, William J., additional, Mulholland, Kim, additional, Mura, Manuela, additional, Musher, Daniel M., additional, Nagel, Maria A., additional, Nair, G. Balakrish, additional, Nelson, Noele P., additional, Netea, Mihai G., additional, Neuzil, Kathleen Maletic, additional, Niemeyer, Christy S., additional, Nohynek, Hanna, additional, Norheim, Gunnstein, additional, Nussbaum, Lauren, additional, O’Brien, Katherine L., additional, O’Leary, Sean, additional, Ockenhouse, Christian, additional, Offit, Paul A., additional, Okwo-Bele, Jean-Marie, additional, Olkhanud, Purevdorj B., additional, Omer, Saad B., additional, Orenstein, Walter A., additional, Oyston, Petra C.F., additional, Parashar, Umesh D., additional, Patel, Manish M., additional, Payne, Daniel C., additional, Pebody, Richard, additional, Pecetta, Simone, additional, Perlman, Stanley, additional, Pierson, Benjamin, additional, Pierson, Theodore C., additional, Pittet, Laure F., additional, Pittman, Phillip R., additional, Plotkin, Stanley A., additional, Plotkin, Susan L., additional, Poland, Gregory A., additional, Pollard, Sir Andrew John, additional, Poovorawan, Yong, additional, Proctor, Richard A., additional, Qadri, Firdausi, additional, Rao, Agam, additional, Rappuoli, Rino, additional, Reef, Susan E., additional, Rogalewicz, Joseph A., additional, Robinson, James Michael, additional, Roesel, Sigrun, additional, Rubin, Steven A., additional, Rupprecht, Charles E., additional, Rutter, Paul, additional, Samant, Vijay B., additional, Sambhara, Suryaprakash, additional, Samies, Nicole L., additional, Santosham, Mathuram, additional, Saunders, Kevin O., additional, Schiller, John T., additional, Schleiss, Mark R., additional, Schuerman, Lode, additional, Schwab, Jennifer, additional, Schwartz, Jason L., additional, Scobie, Heather M., additional, Scott, J. Anthony, additional, Shapiro, Eugene D., additional, Shenoy, Erica S., additional, Shimabukuro, Tom T., additional, Shouval, Daniel, additional, Siegrist, Claire-Anne, additional, Sitrin, Robert D., additional, Skinner, Nicole E., additional, Slifka, Mark K., additional, Sodha, Samir V., additional, Soeters, Heidi M., additional, Solomon, Tom, additional, Speiser, Daniel E., additional, Staples, J. Erin, additional, Steffen, Robert, additional, Stephens, David S., additional, Strebel, Peter M., additional, Subbarao, Kanta, additional, Sullivan, Nancy J., additional, Takashima, Yoshihiro, additional, Tate, Jacqueline E., additional, Tayman, Alice, additional, Telford, Sam R., additional, Thombley, Melisa, additional, Thomsen, Isaac, additional, Tohme, Rania A., additional, Trabold, Malin, additional, El-Turabi, Aadil, additional, Vaughn, David W., additional, Verardi, Raffaello, additional, Vicari, Andrea S., additional, Vidor, Emmanuel J., additional, Villafana, Tonya, additional, Vogt, Matthew R., additional, Walker, Mark J., additional, Walsh, Nick M., additional, Wanlapakorn, Nasamon, additional, Ward, John W., additional, Wassilak, Steven G.F., additional, Watts, Lisa A., additional, Weber, David J., additional, Weiner, David B., additional, Weng, Mark K., additional, Wexler, Deborah L., additional, Wharton, Melinda, additional, Whitley, Richard J., additional, Whitney, Cynthia G., additional, Wiehe, Kevin, additional, Williamson, E. Diane, additional, Wormser, Gary P., additional, Xia, Ningshao, additional, Yildirim, Inci, additional, Zehrung, Darin, additional, and Zweigart, Mark R., additional

Published
2023
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3. Interim Estimates of 2023-24 Seasonal Influenza Vaccine Effectiveness--United States

Author

Frutos, Aaron M., Price, Ashley M., Harker, Elizabeth, Reeves, Emily L., Ahmad, Haris M., Murugan, Vel, Martin, Emily T., House, Stacey, Saade, Elie A., Zimmerman, Richard K., Gaglani, Manjusha, Wernli, Karen J., Walter, Emmanuel B., Michaels, Marian G., Staat, Mary A., Weinberg, Geoffrey A., Selvarangan, Rangaraj, Boom, Julie A., Klein, Eileen J., Halasa, Natasha B., Ginde, Adit A., Gibbs, Kevin W., Zhu, Yuwei, Self, Wesley H., Tartof, Sara Y., Klein, Nicola P., Dascomb, Kristin, DeSilva, Malini B., Weber, Zachary A., Yang, Duck-Hye, Ball, Sarah W., Surie, Diya, DeCuir, Jennifer, Dawood, Fatimah S., Moline, Heidi L., Toepfer, Ariana P., Clopper, Benjamin R., Link-Gelles, Ruth, Payne, Amanda B., Chung, Jessie R., Flannery, Brendan, Lewis, Nathaniel M., Olson, Samantha M., Adams, Katherine, Tenforde, Mark W., Garg, Shikha, Grohskopf, Lisa A., Reed, Carrie, and Ellington, Sascha

Subjects
United States. National Institutes of Health, Merck & Company Inc., Pfizer Inc., Vaccination -- Health aspects, Medical research -- Health aspects, Medicine, Experimental -- Health aspects, Influenza vaccines -- Health aspects, Influenza -- Health aspects, Medical colleges -- Health aspects, Children -- Health aspects, Health, Vanderbilt University. Medical Center
Abstract

Introduction CDC's Advisory Committee on Immunization Practices recommends annual influenza vaccination for all persons aged [greater than or equal to]6 months (1). During previous influenza seasons, influenza vaccination prevented hundreds [...]

Published
2024

5. Preventing Influenza Virus Infection and Severe Influenza Among Pregnant People and Infants.

Author

Olson, Samantha M., Dawood, Fatimah S., Grohskopf, Lisa A., and Ellington, Sascha

Subjects
INFLUENZA prevention, COMMUNICABLE diseases, INFLUENZA vaccines, HOSPITAL care, INFLUENZA, PREGNANT women, ANTIVIRAL agents, COVID-19 pandemic, CHILDREN, PREGNANCY
Abstract

The landscape of research on the benefits of influenza vaccines and antivirals to protect pregnant persons and infants has increased in recent years, while influenza vaccination rates and antiviral usage have declined. Pregnant people and infants <6 months of age are at increased risk of hospitalization with influenza, making protection of this population essential. Maternal influenza vaccination at any time during pregnancy is the best way to reduce the risk of influenza and severe influenza in both pregnant people and their infants <6 months of age. Influenza antiviral medications for pregnant people and infants are also recommended as early as possible if influenza is confirmed or suspected. This report will update on the current research on the benefits of influenza vaccination during pregnancy and influenza antiviral medication for the pregnant person and infant, current Advisory Committee on Immunization Practices recommendations for influenza vaccination in pregnancy and vaccination coverage rates, current influenza antiviral medication guidance and usage rates in pregnancy and among infants, and future directions for influenza pregnancy research. With over half a century of maternal influenza vaccination in the United States, we have improved protection for pregnant persons and infants against influenza, but we still have room for improvement and optimization with new challenges to overcome following the COVID-19 pandemic. By continuing to fill research gaps and increase vaccination coverage and antiviral usage, there is potential for significant reductions in the domestic and global burden of influenza in pregnant persons and infants. [ABSTRACT FROM AUTHOR]

Published
2024
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7. Infectious virus in exhaled breath of symptomatic seasonal influenza cases from a college community

Author

Yan, Jing, Grantham, Michael, Pantelic, Jovan, de Mesquita, P Jacob Bueno, Albert, Barbara, Liu, Fengjie, Ehrman, Sheryl, Milton, Donald K, Adamson, Walt, Beato-Arribas, Blanca, Bischoff, Werner, Booth, William, Cauchemez, Simon, Enstone, Joanne, Ferguson, Neil, Forni, John, Gilbert, Anthony, Grohskopf, Lisa, Hayward, Andrew, Hewitt, Michael, Kang, Ashley, Killingley, Ben, Lambkin-Williams, Robert, Mann, Alex, Milton, Donald, Nguyen-Van-Tam, Jonathan, Noakes, Catherine, Oxford, John, Palmarini, Massimo, Wang, Jennifer, Bennett, Allan, Cowling, Ben, Monto, Arnold, and Tellier, Raymond

Subjects
Prevention, Emerging Infectious Diseases, Lung, Biodefense, Influenza, Pneumonia & Influenza, Infectious Diseases, Vaccine Related, Clinical Research, Infection, Good Health and Well Being, Aerosols, Air Microbiology, Body Mass Index, Cough, Exhalation, Female, Humans, Influenza, Human, Male, Models, Theoretical, Prevalence, RNA, Viral, Respiratory System, Respiratory Tract Infections, Seasons, Students, Temperature, Universities, Vaccination, Young Adult, influenza virus, aerosol, airborne infection, vaccination effects, viral shedding, EMIT Consortium
Abstract

Little is known about the amount and infectiousness of influenza virus shed into exhaled breath. This contributes to uncertainty about the importance of airborne influenza transmission. We screened 355 symptomatic volunteers with acute respiratory illness and report 142 cases with confirmed influenza infection who provided 218 paired nasopharyngeal (NP) and 30-minute breath samples (coarse >5-µm and fine ≤5-µm fractions) on days 1-3 after symptom onset. We assessed viral RNA copy number for all samples and cultured NP swabs and fine aerosols. We recovered infectious virus from 52 (39%) of the fine aerosols and 150 (89%) of the NP swabs with valid cultures. The geometric mean RNA copy numbers were 3.8 × 104/30-minutes fine-, 1.2 × 104/30-minutes coarse-aerosol sample, and 8.2 × 108 per NP swab. Fine- and coarse-aerosol viral RNA were positively associated with body mass index and number of coughs and negatively associated with increasing days since symptom onset in adjusted models. Fine-aerosol viral RNA was also positively associated with having influenza vaccination for both the current and prior season. NP swab viral RNA was positively associated with upper respiratory symptoms and negatively associated with age but was not significantly associated with fine- or coarse-aerosol viral RNA or their predictors. Sneezing was rare, and sneezing and coughing were not necessary for infectious aerosol generation. Our observations suggest that influenza infection in the upper and lower airways are compartmentalized and independent.

Published
2018

8. Severe Acute Respiratory Syndrome Coronavirus 2 Seropositivity among Healthcare Personnel in Hospitals and Nursing Homes, Rhode Island, USA, July-August 2020

Author

Akinbami, Lara J., Chan, Philip A., Vuong, Nga, Sami, Samira, Lewis, Dawn, Sheridan, Philip E., Lukacs, Susan L., Mackey, Lisa, Grohskopf, Lisa A., Patel, Anita, and Petersen, Lyle R.

Subjects
Hospitals -- Health aspects -- Rhode Island, Medical personnel -- Health aspects, Nursing homes -- Health aspects, Health
Abstract

Healthcare personnel face higher risk of infection during the coronavirus disease (COVID-19) pandemic because of their essential role in identifying and treating persons affected (2,2). Although essential workers in many [...]

Published
2021
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9. Prevalence of SARS-CoV-2 Antibodies in First Responders and Public Safety Personnel, New York City, New York, USA, May-July 2020

Author

Sami, Samira, Akinbami, Lara J., Petersen, Lyle R., Crawley, Addie, Lukacs, Susan L., Weiss, Don, Henseler, Rebecca A., Vuong, Nga, Mackey, Lisa, Patel, Anita, Grohskopf, Lisa A., Morgenthau, Beth Maldin, Daskalakis, Demetre, and Pathela, Preeti

Subjects
First responders -- Health aspects, Medical personnel -- Health aspects, Health
Abstract

Coronavirus disease (COVID-19) was recognized in New York City (NYC), New York, USA, in late February 2020 and had spread throughout the community by March 2020 (1). First responders and [...]

Published
2021
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11. Update : Influenza Activity — United States and Worldwide, May 19–September 28, 2019, and Composition of the 2020 Southern Hemisphere Influenza Vaccine

Author

Epperson, Scott, Davis, C. Todd, Brammer, Lynnette, Elal, Anwar Isa Abd, Ajayi, Noreen, Barnes, John, Budd, Alicia P., Burns, Erin, Daly, Peter, Dugan, Vivien G., Fry, Alicia M., Jang, Yunho, Johnson, Sara Jo, Kniss, Krista, Kondor, Rebecca, Grohskopf, Lisa A., Gubareva, Larisa, Merced-Morales, Angiezel, Sessions, Wendy, Stevens, James, Wentworth, David E., Xu, Xiyan, and Jernigan, Daniel

Published
2019

13. SARS-CoV-2 Seroprevalence among Healthcare, First Response, and Public Safety Personnel, Detroit Metropolitan Area, Michigan, USA, May-June 2020

Author

Akinbami, Lara J., Vuong, Nga, Petersen, Lyle R., Sami, Samira, Patel, Anita, Lukacs, Susan L., Mackey, Lisa, Grohskopf, Lisa A., Shehu, Amy, and Atas, Jenny

Subjects
Detroit, Michigan -- Health aspects, Epidemics -- Statistics -- Risk factors -- United States, Peace officers -- Statistics -- Health aspects, Medical personnel -- Statistics -- Health aspects, Health
Abstract

Healthcare, first response (e.g., firefighters, paramedics, emergency medical technicians), and public safety (e.g., law enforcement officers) personnel have served on the front lines of the coronavirus disease (COVID-19) pandemic response [...]

Published
2020
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15. Influenza Activity — United States, September 30–December 1, 2018

Author

Budd, Alicia P., Elal, Anwar Isa Abd, Alabi, Noreen, Barnes, John, Blanton, Lenee, Brammer, Lynnette, Burns, Erin, Cummings, Charisse N., Dugan, Vivien G., Garg, Shikha, Garten, Rebecca, Grohskopf, Lisa A., Gubareva, Larisa, Kniss, Krista, Kramer, Natalie, O’Halloran, Alissa, Sessions, Wendy, Taylor, Calli, Wentworth, David E., Xu, Xiyan, Fry, Alicia M., Katz, Jacqueline, and Jernigan, Daniel

Published
2018

16. Update : Influenza Activity — United States and Worldwide, May 20–October 13, 2018

Author

Chow, Eric J., Davis, C. Todd, Elal, Anwar Isa Abd, Alabi, Noreen, Azziz-Baumgartner, Eduardo, Barnes, John, Blanton, Lenee, Brammer, Lynnette, Budd, Alicia P., Burns, Erin, Davis, William W., Dugan, Vivien G., Fry, Alicia M., Garten, Rebecca, Grohskopf, Lisa A., Gubareva, Larisa, Jang, Yunho, Jones, Joyce, Kniss, Krista, Lindstrom, Stephen, Mustaquim, Desiree, Porter, Rachael, Rolfes, Melissa, Sessions, Wendy, Taylor, Calli, Wentworth, David E., Xu, Xiyan, Zanders, Natosha, Katz, Jacqueline, and Jernigan, Daniel

Published
2018

22. Update : Influenza Activity — United States and Worldwide, May 21–September 23, 2017

Author

Blanton, Lenee, Wentworth, David E., Alabi, Noreen, Azziz-Baumgartner, Eduardo, Barnes, John, Brammer, Lynnette, Burns, Erin, Davis, C. Todd, Dugan, Vivien G., Fry, Alicia M., Garten, Rebecca, Grohskopf, Lisa A., Gubareva, Larisa, Kniss, Krista, Lindstrom, Stephen, Mustaquim, Desiree, Olsen, Sonja J., Roguski, Katherine, Taylor, Calli, Trock, Susan, Xu, Xiyan, Katz, Jacqueline, and Jernigan, Daniel

Published
2017

26. Update : Influenza Activity — United States, October 2–December 17, 2016

Author

Shang, Mei, Blanton, Lenee, Kniss, Krista, Mustaquim, Desiree, Alabi, Noreen, Barnes, Stephen, Budd, Alicia, Davlin, Stacy L., Kramer, Natalie, Garg, Shikha, Cummings, Charisse N., Flannery, Brendan, Fry, Alicia M., Grohskopf, Lisa A., Olsen, Sonja J., Bresee, Joseph, Sessions, Wendy, Garten, Rebecca, Xu, Xiyan, Elal, Anwar Isa Abd, Gubareva, Larisa, Barnes, John, Wentworth, David E., Burns, Erin, Katz, Jacqueline, Jernigan, Daniel, and Brammer, Lynnette

Published
2016

27. Update : Influenza Activity — United States and Worldwide, May 22–September 10, 2016

Author

Budd, Alicia, Blanton, Lenee, Kniss, Krista, Smith, Sophie, Mustaquim, Desiree, Davlin, Stacy L., Kramer, Natalie, Flannery, Brendan, Fry, Alicia M., Grohskopf, Lisa A., Olsen, Sonja J., Bresee, Joseph, Sessions, Wendy, Garten, Rebecca, Xu, Xiyan, Elal, Anwar Isa Abd, Gubareva, Larisa, Barnes, John, Wentworth, David E., Burns, Erin, Katz, Jacqueline, Jernigan, Daniel, and Brammer, Lynnette

Published
2016

29. Influenza Activity — United States, 2015–16 Season and Composition of the 2016–17 Influenza Vaccine

Author

Davlin, Stacy L., Blanton, Lenee, Kniss, Krista, Mustaquim, Desiree, Smith, Sophie, Kramer, Natalie, Cohen, Jessica, Cummings, Charisse Nitura, Garg, Shikha, Flannery, Brendan, Fry, Alicia M., Grohskopf, Lisa A., Bresee, Joseph, Wallis, Teresa, Sessions, Wendy, Garten, Rebecca, Xu, Xiyan, Elal, Anwar Isa Abd, Gubareva, Larisa, Barnes, John, Wentworth, David E., Burns, Erin, Katz, Jacqueline, Jernigan, Daniel, and Brammer, Lynnette

Published
2016

30. Update : Influenza Activity — United States, October 4, 2015–February 6, 2016

Author

Russell, Kate, Blanton, Lenee, Kniss, Krista, Mustaquim, Desiree, Smith, Sophie, Cohen, Jessica, Garg, Shikha, Flannery, Brendan, Fry, Alicia M., Grohskopf, Lisa A., Bresee, Joseph, Wallis, Teresa, Sessions, Wendy, Garten, Rebecca, Xu, Xiyan, Elal, Anwar Isa Abd, Gubareva, Larisa, Barnes, John, Wentworth, David E., Burns, Erin, Katz, Jacqueline, Jernigan, Daniel, and Brammer, Lynnette

Published
2016

33. Update : Influenza Activity — United States, October 4–November 28, 2015

Author

Smith, Sophie, Blanton, Lenee, Kniss, Krista, Mustaquim, Desiree, Steffens, Craig, Reed, Carrie, Bramley, Anna, Flannery, Brendan, Fry, Alicia M., Grohskopf, Lisa A., Bresee, Joseph, Wallis, Teresa, Garten, Rebecca, Xu, Xiyan, Elal, Anwar Isa Abd, Gubareva, Larisa, Barnes, John, Wentworth, David E., Burns, Erin, Katz, Jacqueline, Jernigan, Daniel, and Brammer, Lynnette

Published
2015

36. Prevention and Control of Seasonal Influenza with Vaccines: Recommendations of the Advisory Committee on Immunization Practices -- United States, 2024--25 Influenza Season.

Author

Grohskopf, Lisa A., Ferdinands, Jill M., Blanton, Lenee H., Broder, Karen R., and Loehr, Jamie

Subjects
*MEDICAL protocols, *IMMUNIZATION, *PATIENT safety, *INFLUENZA vaccines, *IMMUNIZATION of older people, *AT-risk people, *TREATMENT effectiveness, *IMMUNIZATION of children, *VACCINATION coverage, *SEASONAL influenza
Abstract

This report updates the 2023--24 recommendations of the Advisory Committee on Immunization Practices (ACIP) concerning the use of seasonal influenza vaccines in the United States (MMWR Recomm Rep 2022;72[No. RR-2]:1--24). Routine annual influenza vaccination is recommended for all persons aged ≥6 months who do not have contraindications. Trivalent inactivated influenza vaccines (IIV3s), trivalent recombinant influenza vaccine (RIV3), and trivalent live attenuated influenza vaccine (LAIV3) are expected to be available. All persons should receive an age-appropriate influenza vaccine (i.e., one approved for their age), with the exception that solid organ transplant recipients aged 18 through 64 years who are receiving immunosuppressive medication regimens may receive either high-dose inactivated influenza vaccine (HD-IIV3) or adjuvanted inactivated influenza vaccine (aIIV3) as acceptable options (without a preference over other age-appropriate IIV3s or RIV3). Except for vaccination for adults aged ≥65 years, ACIP makes no preferential recommendation for a specific vaccine when more than one licensed and recommended vaccine is available. ACIP recommends that adults aged ≥65 years preferentially receive any one of the following higher dose or adjuvanted influenza vaccines: trivalent high-dose inactivated influenza vaccine (HD-IIV3), trivalent recombinant influenza vaccine (RIV3), or trivalent adjuvanted inactivated influenza vaccine (aIIV3). If none of these three vaccines is available at an opportunity for vaccine administration, then any other age-appropriate influenza vaccine should be used. Primary updates to this report include the following two topics: the composition of 2024--25 U.S. seasonal influenza vaccines and updated recommendations for vaccination of adult solid organ transplant recipients. First, following a period of no confirmed detections of wild-type influenza B/Yamagata lineage viruses in global surveillance since March 2020, 2024--25 U.S. influenza vaccines will not include an influenza B/Yamagata component. All influenza vaccines available in the United States during the 2024--25 season will be trivalent vaccines containing hemagglutinin derived from 1) an influenza A/Victoria/4897/2022 (H1N1)pdm09-like virus (for egg-based vaccines) or an influenza A/Wisconsin/67/2022 (H1N1)pdm09-like virus (for cell culture-based and recombinant vaccines); 2) an influenza A/Thailand/8/2022 (H3N2)-like virus (for egg-based vaccines) or an influenza A/Massachusetts/18/2022 (H3N2)-like virus (for cell culture-based and recombinant vaccines); and 3) an influenza B/Austria/1359417/2021 (Victoria lineage)-like virus. Second, recommendations for vaccination of adult solid organ transplant recipients have been updated to include HD-IIV3 and aIIV3 as acceptable options for solid organ transplant recipients aged 18 through 64 years who are receiving immunosuppressive medication regimens (without a preference over other age-appropriate IIV3s or RIV3). This report focuses on recommendations for the use of vaccines for the prevention and control of seasonal influenza during the 2024--25 influenza season in the United States. A brief summary of the recommendations and a link to the most recent Background Document containing additional information are available at https://www.cdc.gov/acip-recs/hcp/vaccine-specific/ flu.html?CDC&lowbar;AAref&lowbar;Val=https://www.cdc.gov/vaccines/hcp/acip-recs/vacc-specific/flu.html. These recommendations apply to U.S.-licensed influenza vaccines. Updates and other information are available from CDC's influenza website (https://www.cdc. gov/flu). Vaccination and health care providers should check this site periodically for additional information. [ABSTRACT FROM AUTHOR]

Published
2024
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44. Evaluating Potential Impacts of a Preferential Vaccine Recommendation for Adults 65 Years of Age and Older on US Influenza Burden.

Author

Morris, Sinead E., Grohskopf, Lisa A., Ferdinands, Jill M., Reed, Carrie, and Biggerstaff, Matthew

Abstract

Background: High-dose, adjuvanted, and recombinant influenza vaccines may offer improved effectiveness among older adults compared with standard-dose, unadjuvanted, inactivated vaccines. However, the Advisory Committee on Immunization Practices (ACIP) only recently recommended preferential use of these "higher-dose or adjuvanted" vaccines. One concern was that individuals might delay or decline vaccination if a preferred vaccine is not readily available. Methods: We mathematically model how a recommendation for preferential use of higher-dose or adjuvanted vaccines in adults ≥65 years might impact influenza burden in the United States during exemplar "high-" and "low-"severity seasons. We assume higher-dose or adjuvanted vaccines are more effective than standard vaccines and that such a recommendation would increase uptake of the former but could cause (i) delays in administration of additional higher-dose or adjuvanted vaccines relative to standard vaccines and/or (ii) reductions in overall coverage if individuals only offered standard vaccines forego vaccination. Results: In a best-case scenario, assuming no delay or coverage reduction, a new recommendation could decrease hospitalizations and deaths in adults ≥65 years by 0%–4% compared with current uptake. However, intermediate and worst-case scenarios, with assumed delays of 3 or 6 weeks and/or 10% or 20% reductions in coverage, included projections in which hospitalizations and deaths increased by over 7%. Conclusions: We estimate that increased use of higher-dose or adjuvanted vaccines could decrease influenza burden in adults ≥65 in the United States provided there is timely and adequate access to these vaccines, and that standard vaccines are administered when they are unavailable. [ABSTRACT FROM AUTHOR]

Published
2023
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48. Recommendations for Postexposure Interventions to Prevent Infection with Hepatitis B Virus, Hepatitis C Virus, or Human Immunodeficiency Virus, and Tetanus in Persons Wounded During Bombings and Similar Mass-Casualty Events — United States, 2008: Recommendations of the Centers for Disease Control and Prevention (CDC)

Author

Chapman, Louisa E., Sullivent, Ernest E., Grohskopf, Lisa A., Beltrami, Elise M., Perz, Joseph F., Kretsinger, Katrina, Panlilio, Adelisa L., Thompson, Nicola D., Ehrenberg, Richard L., Gensheimer, Kathleen F., Duchin, Jeffrey S., Kilmarx, Peter H., and Hunt, Richard C.

Published
2008

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