10 results on '"Groene S"'
Search Results
2. Outcomes of monochorionic twin pregnancies complicated by Type-III selective fetal growth restriction
- Author
-
Shinar, S, Xing, W, Pruthi, V, Jianping, C, Slaghekke, F, Groene, S, Lopriore, E, Lewi, L, Couck, I, Yinon, Y, Batsry, L, Raio, L, Amylidi-Mohr, S, Baud, D, Kneuss, F, DeKoninck, P, Moscou, J, Barrett, J, Melamed, N, Ryan, G, Sun, L, and Van Mieghem, T
- Subjects
610 Medicine & health - Abstract
OBJECTIVE Type III selective intrauterine growth restriction (sIUGR) is associated with a high and unpredictable risk of fetal death and fetal brain injury. Our objective was to describe the prospective risk of fetal death and the risk of adverse neonatal outcomes in a contemporary cohort. METHODS We retrospectively reviewed all monochorionic diamniotic twin pregnancies complicated by type III sIUGR managed at nine fetal centers over a 12-year time period. Higher order multiples, major fetal anomalies or other monochorionicity related complications at initial presentation were excluded. Fetal and neonatal outcomes were collected and management strategies were reviewed. Composite adverse neonatal outcome was defined as neonatal death, invasive ventilation beyond the resuscitation period, culture proven sepsis, necrotizing enterocolitis (NEC) requiring treatment, intraventricular hemorrhage (IVH) >grade I, retinopathy of prematurity (ROP) >stage II or periventricular leukomalacia (PVL). The prospective risk of fetal death and the risk of neonatal complications at each gestational age were evaluated. RESULTS We collected data on 328 pregnancies (656 fetuses). After exclusion of pregnancies which underwent selective reduction (n=18, 5.5%), there were 51 (8.3%) non-iatrogenic fetal deaths in 35 pregnancies (11.3%). Single deaths occurred in 19 (5.8%) pregnancies and double deaths in 16 (4.9%) pregnancies. The prospective risk of non-iatrogenic fetal death per fetus declined from 8.1% (95% CI 5.95-10.26) at 16 weeks, to less than 2% (95% CI 0.59-2.79) after 28.4 weeks and to less than 1% (95% CI -0.30-1.89) beyond 32.6 weeks. In otherwise uncomplicated type III sIUGR, delivery was generally planned at 32 weeks, at which time the risk of composite adverse neonatal outcomes was 29% (31/107 neonates). For twin pregnancies that continued to 34 weeks there was a very low risk of fetal demise (0.7%) and a low risk of adverse outcomes (11%). CONCLUSIONS In this contemporary cohort from tertiary fetal centers, the risk of fetal death in type III sIUGR was lower than previously reported. Further efforts should be directed at identifying predictors of fetal death and optimal antenatal surveillance strategies to select a cohort of pregnancies that can safely continue beyond 33 weeks of gestation. This article is protected by copyright. All rights reserved.
- Published
- 2021
- Full Text
- View/download PDF
3. Outcome of monochorionic twin pregnancy complicated by Type‐III selective intrauterine growth restriction
- Author
-
Shinar, S., primary, Xing, W., additional, Pruthi, V., additional, Jianping, C., additional, Slaghekke, F., additional, Groene, S., additional, Lopriore, E., additional, Lewi, L., additional, Couck, I., additional, Yinon, Y., additional, Batsry, L., additional, Raio, L., additional, Amylidi‐Mohr, S., additional, Baud, D., additional, Kneuss, F., additional, Dekoninck, P., additional, Moscou, J., additional, Barrett, J., additional, Melamed, N., additional, Ryan, G., additional, Sun, L., additional, and Van Mieghem, T., additional
- Published
- 2021
- Full Text
- View/download PDF
4. Growth patterns of monochorionic twin pregnancy complicated by Type-III selective fetal growth restriction.
- Author
-
Shinar, S., Xing, W., Lewi, L., Slaghekke, F., Yinon, Y., Raio, L., Baud, D., DeKoninck, P., Melamed, N., Huszti, E., Sun, L., Van Mieghem, T., Pruthi, V., Jianping, C., Couck, I., Jiang, Y., Groene, S., Lopriore, E., Batsry, L., and Amylidi‐Mohr, S.
- Subjects
FETOFETAL transfusion ,MULTIPLE pregnancy ,FETAL growth retardation ,TWINS ,FETAL growth disorders ,FETAL abnormalities ,BODY weight ,RETROSPECTIVE studies ,FETAL development ,UMBILICAL arteries ,FETAL ultrasonic imaging - Abstract
Objectives: Little is known regarding fetal growth patterns in monochorionic twin pregnancy complicated by Type-III selective fetal growth restriction (sFGR). We aimed to assess fetal growth and umbilical artery Doppler pattern in Type-III sFGR across gestation and evaluate the effect of changing Doppler flow pattern on growth and intertwin growth discordance.Methods: This was a retrospective cohort study of all Type-III sFGR pregnancies managed at nine fetal centers over a 12-year time period. Higher-order multiple pregnancy and cases with major fetal anomaly or other monochorionicity-related complications at presentation were excluded. Estimated fetal weight (EFW) was assessed on ultrasound for each twin pair at five timepoints (16-20, 21-24, 25-28, 29-32 and > 32 weeks' gestation) and compared with singleton and uncomplicated monochorionic twin EFW. EFW and intertwin EFW discordance were compared between pregnancies with normalization of umbilical artery Doppler of the smaller twin later in pregnancy and those with persistently abnormal Doppler.Results: Overall, 328 pregnancies (656 fetuses) met the study criteria. In Type-III sFGR, the smaller twin had a lower EFW than an average singleton fetus (EFW Z-score ranging from -1.52 at 16 weeks to -2.69 at 36 weeks) and an average monochorionic twin in uncomplicated pregnancy (Z-score ranging from -1.73 at 16 weeks to -1.49 at 36 weeks) throughout the entire gestation, while the larger twin had a higher EFW than an average singleton fetus until 22 weeks' gestation and was similar in EFW to an average uncomplicated monochorionic twin throughout gestation. As pregnancy advanced, growth velocity of both twins decreased, with the larger twin remaining appropriately grown and the smaller twin becoming more growth restricted. Intertwin EFW discordance remained stable throughout gestation. On multivariable longitudinal modeling, normalization of fetal umbilical artery Doppler was associated with better growth of the smaller twin (P = 0.002) but not the larger twin (P = 0.1), without affecting the intertwin growth discordance (P = 0.09).Conclusions: Abnormal fetal growth of the smaller twin in Type-III sFGR was evident early in pregnancy, while EFW of the larger twin remained normal throughout gestation. Normalization of umbilical artery Doppler was associated with improved fetal growth of the smaller twin. © 2021 International Society of Ultrasound in Obstetrics and Gynecology. [ABSTRACT FROM AUTHOR]- Published
- 2022
- Full Text
- View/download PDF
5. VP43.21: Outcomes of monochorionic twin pregnancies complicated by type III selective fetal growth restriction
- Author
-
Shinar, S., primary, Xing, W., additional, Pruthi, V., additional, Jianping, C., additional, Slaghekke, F., additional, Groene, S., additional, Lopriore, E., additional, Lewi, L., additional, Couck, I., additional, Yinon, Y., additional, Batsry, L., additional, Raio, L., additional, Amylidi‐Mohr, S., additional, Baud, D., additional, Kneuss, F., additional, De Koninck, P., additional, Moscou, J., additional, Barrett, J., additional, Melamed, N., additional, Ryan, G., additional, Sun, L., additional, and van Mieghem, T., additional
- Published
- 2020
- Full Text
- View/download PDF
6. Milieuscan: zicht op de regionale milieumarkt
- Author
-
Zwol, W.I., Groene, S. de, Ligthart, P.E.M., Zwol, W.I., Groene, S. de, and Ligthart, P.E.M.
- Abstract
Item does not contain fulltext
- Published
- 1998
7. OP04.02: Growth patterns of monochorionic twin pregnancies complicated by type‐3 selective fetal growth restriction.
- Author
-
Shinar, S., Pruthi, V., Jiang, Y., Xing, W., Jianping, C., Lewi, L., Couck, I., Slaghekke, F., Groene, S., Lopriore, E., Yinon, Y., Batsry, L., Raio, L., Amylidi‐Mohr, S., Baud, D., Kneuss, F., De Koninck, P., Moscou, J., Barrett, J., and Melamed, N.
- Subjects
MULTIPLE pregnancy ,FETAL growth retardation ,TWINS ,FETAL growth disorders - Abstract
Conclusions Abnormal fetal growth of the smaller twin in type 3 sFGR was evident from early in pregnancy, while the larger twin's growth remained normal throughout gestation. We aimed to assess fetal growth and Doppler patterns in type 3 sFGR across gestation and evaluate the effect of changing Doppler flow patterns on growth and intertwin weight discordance. OP04.02: Growth patterns of monochorionic twin pregnancies complicated by type-3 selective fetal growth restriction. [Extracted from the article]
- Published
- 2021
- Full Text
- View/download PDF
8. ChemInform Abstract: 3-AMINOINDOLIZINES
- Author
-
FLITSCH, W., primary and KAHNER-GROENE, S., additional
- Published
- 1982
- Full Text
- View/download PDF
9. Artery-to-vein anastomoses in unequally divided placentas and their association with birthweight discordance.
- Author
-
Noll ATR, Lof FC, Groene SG, Haak MC, Lopriore E, Russo FM, Slaghekke F, Tollenaar LSA, Van der Merwe J, Verweij EJT, and Lewi L
- Subjects
- Pregnancy, Female, Humans, Birth Weight, Retrospective Studies, Twins, Monozygotic, Arteries, Pregnancy, Twin, Fetal Growth Retardation, Placenta blood supply, Fetofetal Transfusion
- Abstract
Introduction: This study investigated the impact of the shared intertwin circulation in unequally divided monochorionic (MC) placentas on fetal growth., Methods: This retrospective analysis included color-dyed, unequally shared placentas from two tertiary centers. Exclusions included twin-twin transfusion syndrome, twin anemia polycythemia sequence, and lethal anomalies. Measurement of the external diameters and areas of the artery-to-artery (AA), artery-to-vein (AV), and vein-to-vein (VV) anastomoses was performed. The ratio of the shared circulation (AV ratio) was determined by comparing the areas of the summed venous components of shared AV anastomoses to those in the individual AV anastomoses of the smaller placental part. The birth weight ratio/placental ratio (BWR/PR), total AV size areas and net AV transfusion were calculated. Univariable and multivariable linear regressions were performed to assess the relationship between BWR/PR, the AV ratio, the areas of the different anastomoses and cord insertion discordance., Results: Among 352 placentas, 97 % (340) had intertwin AV anastomoses, and 50 % (176) were from pregnancies with selective growth restriction. The AV ratio, AA, VV, total AV areas, and cord insertion discordance negatively correlated with BWR/PR. Multivariable linear regression confirmed the independent negative association between BWR/PR and the AV ratio, suggesting that a larger shared circulation benefits the twin with the smaller placental part. Type III sFGR placentas exhibited the highest AV ratio, resulting in the lowest BWR/PR., Discussion: A larger shared circulation mitigates the impact of an unequally divided placenta on fetal growth. This effect surpasses the influence of AA and VV diameters and is most prominent in Type III sFGR placentas., Competing Interests: Declaration of competing interest None, (Copyright © 2024 Elsevier Ltd. All rights reserved.)
- Published
- 2024
- Full Text
- View/download PDF
10. Placental characteristics in monochorionic twins with selective intrauterine growth restriction in relation to the umbilical artery Doppler classification.
- Author
-
Groene SG, Tollenaar LSA, Slaghekke F, Middeldorp JM, Haak M, Oepkes D, and Lopriore E
- Subjects
- Adult, Female, Humans, Male, Pregnancy, Fetal Growth Retardation pathology, Placenta pathology, Placentation, Twinning, Monozygotic, Twins, Monozygotic
- Abstract
Introduction: The objective of this study was to evaluate the placental characteristics of monochorionic twin pregnancies with selective intrauterine growth restriction (sIUGR) classified according to the Gratacós classification based on umbilical artery Doppler measurements., Methods: All consecutive placentas from monochorionic twin pregnancies with sIUGR, (defined as a birthweight discordance > 25% and/or an estimated fetal weight in one twin <10th centile) examined between May 2002 and February 2018 were included in the study. Each placenta was injected with colored dye to study the angioarchitecture. Primary outcomes were placental share discordance and diameter of the arterio-arterial anastomoses in relation to the umbilical artery Doppler types of sIUGR (Gratacós classification)., Results: Of the 83 sIUGR twins included, 27 were classified as Gratacós type I, 24 as type II and 32 as type III. The median gestational age at delivery was 34.3 weeks for type I, compared to 31.2 weeks and 31.6 weeks for type II and type III respectively. A trend towards a higher placental share discordance in type III sIUGR was observed. The median arterio-arterial diameter was 1.7 mm (0.8-2.6) in type I, 1.7 mm (1.2-2.2) in type II and 2.8 (2.0-3.5) mm in type III (p < 0.01)., Discussion: Type III sIUGR placentas appear to be characterized by a larger diameter of the arterio-arterial anastomoses and a larger placental share discordance compared to type I and II sIUGR. The insights in the placental architecture of sIUGR placentas may offer new views on the pathophysiology of the disease., (Copyright © 2018 Elsevier Ltd. All rights reserved.)
- Published
- 2018
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.