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9 results on '"Grewal, Manpreet K."'

1. Primary Hypertension in Children

Author

Grewal, Manpreet K., Mattoo, Tej K., Kapur, Gaurav, Flynn, Joseph T., Section editor, Flynn, Joseph T., editor, Ingelfinger, Julie R., editor, and Brady, Tammy M., editor

Published
2023
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3. Renal replacement therapy in the management of intoxications in children: recommendations from the Pediatric Continuous Renal Replacement Therapy (PCRRT) workgroup

Author

Raina, Rupesh, Grewal, Manpreet K, Blackford, Martha, Symons, Jordan M., Somers, Michael J. G., Licht, Christoph, and Basu, Rajit K

Subjects
United States -- Conferences, meetings and seminars, Children -- Health aspects, Health
Abstract

Background Intentional or unintentional ingestions among children and adolescents are common. There are a number of ingestions amenable to renal replacement therapy (RRT). Methods We systematically searched PubMed/Medline, Embase, and Cochrane databases for literature regarding drugs/intoxicants and treatment with RRT in pediatric populations. Two experts from the PCRRT (Pediatric Continuous Renal Replacement Therapy) workgroup assessed titles, abstracts, and full-text articles for extraction of data. The data from the literature search was shared with the PCRRT workgroup and two expert toxicologists, and expert panel recommendations were developed. Results and Conclusions We have presented the recommendations concerning the use of RRTs for treatment of intoxications with toxic alcohols, lithium, vancomycin, theophylline, barbiturates, metformin, carbamazepine, methotrexate, phenytoin, acetaminophen, salicylates, valproic acid, and aminoglycosides., Author(s): Rupesh Raina [sup.1] [sup.2] , Manpreet K Grewal [sup.2] , Martha Blackford [sup.3] , Jordan M. Symons [sup.4] , Michael J. G. Somers [sup.5] , Christoph Licht [sup.6] , [...]

Published
2019
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4. Consensus guidelines for management of hyperammonaemia in paediatric patients receiving continuous kidney replacement therapy

Author

Raina, Rupesh, Bedoyan, Jirair K., Lichter-Konecki, Uta, Jouvet, Philippe, Picca, Stefano, Mew, Nicholas Ah, Machado, Marcel C., Chakraborty, Ronith, Vemuganti, Meghana, Grewal, Manpreet K., Bunchman, Timothy, Sethi, Sidharth Kumar, Krishnappa, Vinod, McCulloch, Mignon, Alhasan, Khalid, Bagga, Arvind, Basu, Rajit K., Schaefer, Franz, Filler, Guido, and Warady, Bradley A.

Published
2020
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6. Optimal management of atypical hemolytic uremic disease: challenges and solutions

Author

Raina, Rupesh, Grewal, Manpreet K, Radhakrishnan, Yeshwanter, Tatineni, Vineeth, DeCoy, Meredith, Burke, Linda LG, and Bagga, Arvind

Subjects
atypical hemolytic uremic syndrome, hemic and lymphatic diseases, eculizumab, challenges, Review, urologic and male genital diseases, thrombotic microangiopathy
Abstract

Atypical hemolytic uremic syndrome (aHUS) is a chronic life threatening condition that arises from genetic abnormalities resulting in uncontrolled complement amplifying activity. The introduction of eculizumab, the humanized monoclonal antibody, has brought about a paradigm shift in the management of aHUS. However, there are many knowledge gaps, diagnostic issues, access and cost issues, and patient or physician challenges associated with the use of this agent. Limited data on the natural history of aHUS along with the underlying genetic mutations make it difficult to predict the relapses and thereby raising concerns about the appropriate duration and monitoring of treatment. In this review, we discuss the safety and efficacy of eculizumab in patients with aHUS and its associated challenges.

Published
2019

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