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1. Template-assisted covalent modification underlies activity of covalent molecular glues

4. Reciprocal antagonism of PIN1-APC/CCDH1 governs mitotic protein stability and cell cycle entry

5. Targeting DCAF5 suppresses SMARCB1-mutant cancer by stabilizing SWI/SNF

8. Targeting transcription in heart failure via CDK7/12/13 inhibition

9. Rewiring cancer drivers to activate apoptosis

10. Depletion of creatine phosphagen energetics with a covalent creatine kinase inhibitor

11. Author Correction: Targeting DCAF5 suppresses SMARCB1-mutant cancer by stabilizing SWI/SNF

12. Inhibition of CDK4/6 promotes CD8 T-cell memory formation

13. Genome-scale functional genomics identify genes preferentially essential for multiple myeloma cells compared to other neoplasias

15. The ETS transcription factor ETV6 constrains the transcriptional activity of EWS–FLI to promote Ewing sarcoma

17. New scaffolds for type II JAK2 inhibitors overcome the acquired G993A resistance mutation

18. CDK7 controls E2F- and MYC-driven proliferative and metabolic vulnerabilities in multiple myeloma

19. Salt-inducible kinase 1 maintains HDAC7 stability to promote pathologic cardiac remodeling

20. USP9X mediates an acute adaptive response to MAPK suppression in pancreatic cancer but creates multiple actionable therapeutic vulnerabilities

23. Exploring the target scope of KEAP1 E3 ligase-based PROTACs

26. An allosteric inhibitor against the therapy-resistant mutant forms of EGFR in non-small cell lung cancer

28. Author Correction: Tuning microtubule dynamics to enhance cancer therapy by modulating FER-mediated CRMP2 phosphorylation

30. Disrupting the RNA polymerase II transcription cycle through CDK7 inhibition ameliorates inflammatory arthritis.

31. Discovery of Potent Degraders of the Dengue Virus Envelope Protein.

32. DCLK1 induces a pro-tumorigenic phenotype to drive gastric cancer progression.

35. The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations

37. Structure-activity relationship study of THZ531 derivatives enables the discovery of BSJ-01-175 as a dual CDK12/13 covalent inhibitor with efficacy in Ewing sarcoma

38. Sulfopin is a covalent inhibitor of Pin1 that blocks Myc-driven tumors in vivo

40. A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles

42. Discovery and resistance mechanism of a selective CDK12 degrader

43. Targeted brachyury degradation disrupts a highly specific autoregulatory program controlling chordoma cell identity

44. ULK1 inhibition overcomes compromised antigen presentation and restores antitumor immunity in LKB1-mutant lung cancer

45. Down-Regulation of AKT Proteins Slows the Growth of Mutant-KRAS Pancreatic Tumors.

48. Targeting the PI5P4K Lipid Kinase Family in Cancer Using Covalent Inhibitors

49. Exploring Targeted Degradation Strategy for Oncogenic KRASG12C

50. Multiomic profiling of breast cancer cells uncovers stress MAPK-associated sensitivity to AKT degradation

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