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1,296 results on '"Grassi, L."'

1. Pulse shape discrimination for GRIT: beam test of a new integrated charge and current preamplifier coupled with high granularity Silicon detectors

Author

Dormard, J. -J., Assié, M., Grassi, L., Rauly, E., Beaumel, D., Brulin, G., Chabot, M., Coacolo, J. -L., Flavigny, F., Genolini, B., Hammache, F., Barkach, T. Id, Rindel, E., Rosier, Ph., de Séréville, N., and Wanlin, E.

Subjects
Physics - Instrumentation and Detectors, Nuclear Experiment
Abstract

The GRIT (Granularity, Resolution, Identification, Transparency) Silicon array is intended to measure direct reactions. Its design is based on several layers (three layers in the forward direction, two backward) of custom-made trapezoidal and square detectors. The first stage is 500 {\mu}m thick and features 128x128 orthogonal strips. Pulse shape analysis for particle identification is implemented for this first layer. Given the compacity of this array and the large number of channels involved (>7,500), an integrated preamplifier, iPACI, that gives charge and current information has been developed in the AMS 0.35 {\mu}m BiCMOS technology. The design specifications and results of the test bench are presented. Considering an energy range of 50 MeV and an energy resolution (FWHM) of 12 keV (FWHM) for the preamplifier, the energy resolution for one strip obtained from alpha source measurement in real conditions is 35 keV. The current output bandwidth is measured at 130 MHz for small signals and the power consumption reaches 40 mW per detector channel. A first beam test was performed coupling a nTD trapezoidal double-sided stripped Silicon detector of GRIT with the iPACI preamplifier and a 64-channel digitizer. Z=1 particles are discriminated with pulse shape analysis technique down to 2 MeV for protons, 2.5 MeV for deuterons and 3 MeV for tritons. The effect of the strip length due to the trapezoidal shape of the detector is investigated on both the N- and the P-side, showing no significant impact.

Published
2021

6. Infective endocarditis in adult patients with congenital heart disease

Author

Habib, Gilbert, Lancellotti, Patrizio, Cosyns, Bernard, Donal, Erwan, Erba, Paola, Iung, Bernard, Maggioni, Aldo P., Popescu, Bogdan A., Prendergast, Bernard, Tornos, Pilar, Tatar-Chentir, Nora Nabila Ali, Al-Mallah, Mouaz, Aneq, Meriam Astrom, Athanassopoulos, George, Badano, Luigi Paolo, Benyoussef, Soraya, Aranda, Erick Calderon, Cardim, Nuno Miguel, Chan, Kwan-Leung, Cruz, Ines, Edvardsen, Thor, Goliasch, Georg, Hagendorff, Andreas, Hristova, Krasimira, Kamp, Otto, Kang, Duk-Hyun, Kong, William, Matskeplishvili, Simon, Meshaal, Marwa, Mirocevic, Maja, Neskovic, Aleksandar N., Pazdernik, Michal, Plonska-Gosciniak, Edyta, Raissouni, Maha, Ronderos, Ricardo, Sade, Leyla Elif, Sadeghpour, Anita, Sambola, Antonia, Sengupta, Shantanu, Separovic-Hanzevacki, Jadranka, Takeuchi, Masaaki, Tucay, Edwin, Rodrigues, Ana Clara Tude, Varga, Albert, Vaskelyte, Jolanta, Yamagata, Kentaro, Yiangou, Kyriakos, Zaky, Hosam, Ronderos, R., Avegliano, G., Oses, P. Fernandez, Filipini, E., Granada, I., Iribarren, A., Mahia, M., Nacinovich, F., Ressi, S., Obregon, R., Bangher, M., Dho, J., Cartasegna, L., Plastino, M.L., Novas, V., Shigel, C., Reyes, G., De Santos, M., Gastaldello, N., Fernandez, M. Granillo, Potito, M., Streitenberger, G., Velazco, P., Casabé, J.H., Cortes, C., Guevara, E., Salmo, F., Seijo, M., Weidinger, F., Heger, M., Brooks, R., Stöllberger, C., Ho, C.-Y., Perschy, L., Puskas, L., Goliasch, G., Binder, C., Rosenhek, R., Schneider, M., Winter, M.-P., Hoffer, E., Melissopoulou, M., Lecoq, E., Legrand, D., Jacquet, S., Massoz, M., Lancellotti, P., Pierard, L., Dulgheru, R., Marchetta, S., D'Emal, C., Oury, C., Cosyns, B., Droogmans, S., Kerkhove, D., Motoc, A., Plein, D., Roosens, B., Soens, L., Weytjens, C., Lemoine, I., Rodrigus, I., Paelinck, B., Amsel, B., Unger, P., Konopnicki, D., Beauloye, C., Pasquet, A., Pierard, S., Vancraeynest, D., Vanoverschelde, J.L., Sinnaeve, F., Andrade, J.L., Rodrigues, A.C. Tude, Staszko, K., Monteiro, R. Dos Santos, Miglioranza, M.H., Shuha, D.L., Alcantara, M., Cravo, V., Fazzio, L., Felix, A., Iso, M., Musa, C., Siciliano, A.P., Filho, F. Villaca, Braga, J., Rodrigues, A., Silva, R., Vilela, F., Rodrigues, D., Silva, L., Morhy, S., Fischer, C., Vieira, M., Afonso, T., Abreu, J., Falcao, S.N., Moises, V., Gouvea, A., João, G., Mancuso, F., Silva, C., Souza, A.C., Abboud, C.S., de Mattos Barretto, R. Bellio, Ramos, A., Arnoni, R., Assef, J.E., Togna, D.J. Della, Le Bihan, D., Miglioli, L., Oliveira, A.P. Romero, Kroll, R. Tadeu Magro, Cortez, D., Gelape, C.L., Nunes, M.d.C. Peirira, Ferrari, T.C. De Abreu, Chan, K.-L., Hay, K., Le, V., Page, M., Poulin, F., Sauve, C., Serri, K., Mercure, C., Beaudoin, J., Pibarot, P., Sebag, I., Rudski, L., Ricafort, G., Barsic, B., Krajinovic, V., Vargovic, M., Separovic-Hanzevacki, J., Lovric, D., Reskovic-Luksic, V., Vincelj, J., Jurinjak, S. Jaksic, Yiannikourides, V., Ioannides, M., Kyriakou, C., Pofaides, C., Masoura, V., Yiangou, K., Pudich, J., Linhart, A., Siranec, M., Marek, J., Blechova, K., Kamenik, M., Pazdernik, M., Pelouch, R., Coufal, Z., Mikulica, M., Griva, M., Jancova, E., Mikulcova, M., Taborsky, M., Precek, J., Jecmenova, M., Latal, J., Widimsky, J., Butta, T., Machacek, S., Vancata, R., Spinar, J., Holicka, M., Long, F. Pow Chon, Anzules, N., Carpio, A. Bajana, Largacha, G., Penaherrera, E., Moreira, D., Mahfouz, E., Elsafty, E., Soliman, A., Zayed, Y., Aboulenein, J., Abdel-Hay, M., Almaghraby, A., Abdelnaby, M., Ahmed, M., Hammad, B., Saleh, Y., Zahran, H., Elgebaly, O., Saad, A., Ali, M., Zeid, A., El Sharkawy, R., Meshaal, M., Al Kholy, A., Doss, R., Osama, D., Rizk, H., Elmogy, A., Mishriky, M., Assayag, P., El Hatimi, S., Botelho-Nevers, E., Campisi, S., Fuzellier, J.-F., Gagneux-Brunon, A., Pierrard, R., Tulane, C., Detoc, M., Mehalla, T., Boutoille, D., Al Habash, O., Asseray-Madani, N., Biron, C., Brochard, J., Caillon, J., Cueff, C., Le Tourneau, T., Lecompte, A.S., Lecomte, R., Lefebvre, M., Michel, M.M. Magali, Pattier, S., Delarue, S., Le Bras, M., Orain, J., Faucher, J.-F., Aboyans, V., Beeharry, A., Durox, H., Lacoste, M., Magne, J., Mohty, D., David, A., Pradel, V., Sierra, V., Neykova, A., Bettayeb, B., Elkentaoui, S., Tzvetkov, B., Landry, G., Strady, C., Ainine, K., Baumard, S., Brasselet, C., Tassigny, C., Valente-Pires, V., Lefranc, M., Hoen, B., Lefevre, B., Curlier, E., Callier, C., Fourcade, N., Jobic, Y., Ansard, S., Le Berre, R., Le Roux, P., Le Ven, F., Pouliquen, M.-C., Prat, G., Bouchart, F., Savoure, A., Alarcon, C., Chapuzet, C., Gueit, I., Tribouilloy, C., Bohbot, Y., Peugnet, F., Gun, M., Iung, B., Duval, X., Lescure, X., Ilic-Habensus, E., Sadoul, N., Selton-Suty, C., Alla, F., Chevalier, E., Goehringer, F., Huttin, O., Garcia, R., Le Marcis, V., Tattevin, P., Donal, E., Flecher, E., Revest, M., Habib, G., Hubert, S., Casalta, J.-P., Gouriet, F., Arregle, F., Cammilleri, S., Tessonnier, L., Riberi, A., Chirouze, C., Bouiller, K., Brunel, A.-S., Fournier, D., Hustache-Mathieu, L., Klopfenstein, T., Moreau, J., Lim, P., Oliver, L., Ternacle, J., Moussafeur, A., Chavanet, P., Piroth, L., Buisson, M., Mahy, S., Martins, C., Salmon-Rousseau, A., Gohier, S., Piper, C., Börgermann, J., Guckel, D., Horstkotte, D., Brockmeier, B., Winkelmann, E., Hagendorff, A., Grey, D., Nickenig, G., Schueler, R., Öztürk, C., Stöhr, E., Hamm, C., Walther, T., Brandt, R., Frühauf, A.-C., Hartung, C.T., Hellner, C., Wild, C., Becker, M., Hamada, S., Kaestner, W., Stangl, K., Knebel, F., Baldenhofer, G., Brecht, A., Dreger, H., Isner, C., Pfafflin, F., Stegemann, M., Zahn, R., Fraiture, B., Kilkowski, C., Karcher, A.-K., Klinger, S., Tolksdorf, H., Tousoulis, D., Aggeli, C., Sarri, G., Sideris, S., Venieri, E., Athanassopoulos, G., Tsiapras, D., Armenis, I., Koutsiari, A., Floros, G., Grassos, C., Dragasis, S., Rallidis, L., Varlamos, C., Michalis, L., Naka, K., Bechlioulis, A., Kotsia, A., Lakkas, L., Pappas, K., Papadopoulos, C., Kiokas, S., Lioni, A., Misailidou, S., Barbetseas, J., Bonou, M., Kapelios, C., Tomprou, I., Zerva, K., Manolis, A., Hamodraka, E., Athanasiou, D., Haralambidis, G., Poulimenos, L., Samaras, H., Nagy, A., Bartykowszki, A., Gara, E., Sengupta, S., Mungulmare, K., Kasliwal, R., Bansal, M., Bhan, A., Ranjan, S., Kyavar, M., Maleki, M., Bezanjani, F. Noohi, Sadeghpour, A., Alizadehasl, A., Boudagh, S., Ghavidel, A., Moradnejad, P., Pasha, H.R., Ghadrdoost, B., Gilon, D., Strahilevitz, J., Israel, S., Wanounou, M., d'Agostino, C., Colonna, P., De Michele, L., Fumarola, F., Stante, M., Marchionni, N., Scheggi, V., Alterini, B., Del Pace, S., Stefano, P., Sparano, C., Badano, L.P., Muraru, D., Ruozi, N., Tenaglia, R., Limbruno, U., Cresti, A., Baratta, P., Solari, M., Giannattasio, C., Moreo, A., De Chiara, B., Montero, B. Lopez, Musca, F., Orcese, C.A., Panzeri, F., Russo, C.F., Spano, F., Alfieri, O., De Bonis, M., Agricola, E., Busnardo, E., Carletti, S., Castiglioni, B., Chiappetta, S., Del Forno, B., Ferrara, D., Guffanti, M., Iaci, G., Lapenna, E., Nisi, T., Oltolini, C., Pajoro, U., Pasciuta, R., Ripa, M., Scarpellini, P., Din, C. Tassan, Meneghin, R., Schiavi, D., Piscione, F., Citro, R., Benvenga, R.M., Greco, L., Prota, C., Radano, I., Soriente, L., Bellino, M., Di Vece, D., Santini, F., Salsano, A., Olivieri, G.M., Turrini, F., Messora, R., Tondi, S., Olaru, A., Agnoletto, V., Grassi, L., Leonardi, C., Sansoni, S., Del Ponte, S., Dato, G.M. Actis, De Martino, A., Ohte, N., Kikuchi, S., Wakami, K., Aonuma, K., Seo, Y., Ishizu, T., Machino-Ohtsuka, T., Yamamoto, M., Iida, N., Nakajima, H., Nakagawa, Y., Izumi, C., Amano, M., Miyake, M., Takahashi, K., Shiojima, I., Miyasaka, Y., Maeba, H., Suwa, Y., Taniguchi, N., Tsujimoto, S., Kitai, T., Ota, M., Yuda, S., Sasaki, S., Hagiwara, N., Yamazaki, K., Ashihara, K., Arai, K., Saitou, C., Saitou, S., Suzuki, G., Shibata, Y., Watanabe, N., Nishino, S., Ashikaga, K., Kuriyama, N., Mahara, K., Abe, K., Fujimaki, H., Okubo, T., Shitan, H., Takanashi, S., Terada, M., Yamamoto, H., Sata, M., Yamada, H., Kusunose, K., Saijo, Y., Seno, H., Yuichiro, O., Sakata, Y., Mizuno, H., Nakatani, S., Onishi, T., Sengoku, K., Sera, F., Park, S.W., Kyoung, K. Eun, Yeon, L. Ga, Hwang, J.-W., Jin-Oh, C., Park, S.-J., Sang-Chol, L., Sung-A, C., Jang, S.Y., Kang, D.-H., Heo, R., Lee, S., Song, J.-M., Jung, E., Plisiene, J., Dambrauskaite, A., Gruodyte, G., Jonkaitiene, R., Vaskelyte, J., Mizariene, V., Atkocaityte, J., Zvirblyte, R., Sow, R., Codreanu, A., De la Vega, E.C.L., Michaux, C., Staub, T., Jacobs-Orazi, L., Azzopardi, C. Mallia, Xuereb, R.G., Piscopo, T., Borg, D., Casha, R., Farrugia, J., Fenech, M., Pllaha, E., Vella, C., Yamagata, K., Grib, L., Raevschi, E., Grejdieru, A., Balan, G., Cardaniuc, I., Cardaniuc, L., Corcea, V., Feodorovici, A., Gaina, V., Girbu, L., Jimbei, P., Kravcenco, D., Panfile, E., Prisacari, E., Samohvalov, E., Samohvalov, S., Sceglova, N., Benesco, I., Marian, V., Sumarga, N., Mirocevic, M., Bozovic, B., Bulatovic, N., Lakovic, P., Music, L., Roos-Hesselink, J., Budde, R., Gamela, T., Wahadat, A., Kamp, O., Meijers, T., Van Melle, J.P., Deursen, V.M., Crijns, H., Bekkers, S., Cheriex, E., Gilbers, M., Kietselaer, B., Knackstedt, C., Lorusso, R., Schalla, S., Streukens, S., Chamuleau, S., Cramer, M.-J., Teske, A., Van der Spoel, T., Wind, A., Liesbek, O., Lokhorst, J., Van Heusden, H., Tanis, W., Van der Bilt, I., Vriend, J., Bruggen, H. De Lange-van, Karijodikoro, E., Riezebos, R., van Dongen, E., Schoep, J., Stolk, V., Axler, O., Baumann, F., Lebras, S., Edvardsen, T., Offstad, J.T., Beitnes, J.O., Helle-Valle, T., Skulstad, H., Skardal, R., Qamar, N., Furnaz, S., Ahmed, B., Butt, M.H., Khanzada, M.F., Saghir, T., Wahid, A., Hryniewiecki, T., Szymanski, P., Marzec, K., Misztal-Ogonowska, M., Kosmala, W., Przewlocka-Kosmala, M., Rojek, A., Woznicka, K., Zachwyc, J., Lisowska, A., Kaminska, M., Kasprzak, J., Kowalczyk, E., Strzecka, D.F., Wejner-Mik, P., Trabulo, M., Freitas, P., Ranchordas, S., Rodrigues, G., Pinto, P., Queiros, C., Azevedo, J., Marques, L., Seabra, D., Branco, L., Cruz, M., Galrinho, A., Moreira, R., Rio, P., Timoteo, A.T., Selas, M., Cardim, N.M., Carmelo, V., Neves, B. Duque, Pereira, H., Cruz, I., Guerra, A., Marques, A., Pintassilgo, I., Tomescu, M.C., Trofenciuc, N.-M., Andor, M., Bordejevic, A., Branea, H.S., Caruntu, F., Cirin, L., Citu, I.M., Cotoraci, C.A., Darabantiu, D., Farcas, R., Marincu, I., Mavrea, A., Onel, M.F., Parvanescu, T., Pop, D., Pop-Moldovan, A.L., Puticiu, M.I., Velcean, L.A., Ionac, A., Cozma, D., Mornos, C., Goanta, F., Popescu, I., Beyer, R., Mada, R., Rancea, R., Rosianu, H., Tomoaia, R., Stanescu, C., Kobalava, Z., Karaulova, J., Kotova, E., Milto, A., Pisaryuk, A., Povalyaev, N., Sorokina, M., Alrahimi, J., Elshiekh, A., Jamiel, A., Ahmed, A., Al-Mallah, M., Attia, N., Putnikovic, B., Neskovic, A., Dimic, A., Ivanovic, B., Matic, S., Trifunovic, D., Petrovic, J., Kosevic, D., Dabic, P., Milojevic, P., Petrovic, I., Stojanovic, I., Srdanovic, I., Kovacevic, M., Redzek, A., Stefanovic, M., Susak, S., Velicki, L., Vulin, A., Yeo, T.C., Kong, W.K.F., Poh, K.K., Vilacosta, I., El-Nasser, M. Abd, Ferrera, C., Olmos, C., Iglesias, F. Calvo, Blanco-Gonzalez, E., Amaro, M. Bravo, Germinas, A.N., Lopez-Rodriguez, E., Adan, J. Lugo, Pazos-Lopez, P., Loureiro, M. Pereira, Perez, M.T., Raposeiras-Roubin, S., Yas, S. Rasheed, Suarez-Varela, M.-M., Vidal, F. Vasallo, Garcia-Dorado, D., Sambola, A., Fernandez-Hidalgo, N., Gonzalez-Alujas, T., Lozano, J., Maisterra, O., Pizzi, N., Rios, R., Tornos, P., Bayes-Genis, A., Botet, L. Pedro, Vallejo, N., Berastegui, E., Llibre, C., Mateu, L., Nunez, R., Quesada, D., Portell, D. Bosch, Vinas, J. Aboal, Bertran, X. Albert, Tarradellas, R. Brugada, Ricon, P. Loma-Osorio, de Llano, C. Tiron, Arnau, M.A., Bel, A., Blanes, M., Osa, A., Anguita, M., Carrasco, F., Castillo, J., Zamorano, J.L., Mur, J.L. Moya, Alvaro, M., Fernandez-Golfin, C., Monteagudo, J.M., Elorza, E. Navas, Alvarez, M.C. Farinas, Balbin, J. Aguero, Arminanzas, C., de las Revillas, F. Arnaiz, Garcia, A. Arnaiz, Belaustegui, M. Cobo, Sampedro, M. Fernandez, Cuadra, M. Gutierrez, Gutierrez-Diez, J.F., Zarauza, J., Cuello, L. Garcia, Rico, C. Gonzalez, Rodriguez-Alvarez, R., Goikoetxea, J., Montejo, M., Miro, J., Almela, M., Ambrosioni, J., Falces, C., Fuster, D., Garcia-de-la-Maria, C., Hernandez-Meneses, M., Llopis, J., Marco, F., Moreno, A., Quintana, E., Sandoval, E., Tellez, A., Tolosana, J.M., Vidal, B., Ruiz-Zamora, I., Ruiz, A. Bardaji, Girgas, E. Sanz, Garcia-Pardo, G., Marzo, M. Guillen, Oviedo, A. Rodriguez, Jimenez, A. Villares, Abid, L., Hammami, R., Kammoun, S., Mourali, M.S., Zghal, F. Mghaieth, Hlima, M. Ben, Boudiche, S., Ouali, S., Zakhama, L., Antit, S., Slama, I., Gulel, O., Sahin, M., Sade, L.E., Karacaglar, E., Kucukoglu, S., Cetinarslan, O., Yasar, U.S., Canpolat, U., Mutlu, B., Atas, H., Dervishova, R., Ileri, C., Zaky, H., Alhashmi, J., Baslib, F., Tahir, J., Zarger, P., Woldman, S., Menezes, L., Primus, C., Uppal, R., Bvekerwa, I., Chandrasekaran, B., Kopanska, A., Prendergast, B., Cannata, S., Chambers, J., Hancock, J., Klein, J., Rajani, R., Ursi, M.P., Dworakowski, R., Fife, A., Breeze, J., Browne-Morgan, M., Gunning, M., Streather, S., Asch, F., Zemedkun, M., Alyavi, B., Uzokov, J., van Melle, Joost P., Roos-Hesselink, Jolien W., Bansal, Manish, Pudich, Jiri, Luksic, Vlatka Reskovic, Rodriguez-Alvarez, Regino, Hanzevacki, Jadranka Separovic, Sow, Rouguiatou, Timóteo, Ana Teresa, Morgado, Marisa Trabulo, De Bonis, Michele, Laroche, Cecile, and Boersma, Eric

Published
2023
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7. The FAZIA setup: a review on the electronics and the mechanical mounting

Author

Valdré, S., Casini, G., Neindre, N. Le, Bini, M., Boiano, A., Borderie, B., Edelbruck, P., Poggi, G., Salomon, F., Tortone, G., Alba, R., Barlini, S., Bonnet, E., Bougault, R., Bougard, A., Brulin, G., Bruno, M., Buccola, A., Camaiani, A., Chbihi, A., Ciampi, C., Cicerchia, M., Cinausero, M., Dell'Aquila, D., Desrues, P., Dueñas, J. A., Fabris, D., Falorsi, M., Frankland, J. D., Frosin, C., Galichet, E., Giordano, R., Gramegna, F., Grassi, L., Gruyer, D., Guerzoni, M., Henri, M., Kajetanowicz, M., Korcyl, K., Kordyasz, A., Kozik, T., Lecompte, P., Lombardo, I., Lopez, O., Maiolino, C., Mantovani, G., Marchi, T., Margotti, A., Merrer, Y., Morelli, L., Olmi, A., Ordine, A., Ottanelli, P., Pain, C., Pałka, M., Pârlog, M., Pasquali, G., Pastore, G., Piantelli, S., de Préaumont, H., Revenko, R., Richard, A., Rivet, M. F., Ropert, J., Rosato, E., Saillant, F., Santonocito, D., Scarlini, E., Serra, S., Soulet, C., Spadaccini, G., Stefanini, A. A., Tobia, G., Upadhyaya, S., Vanzanella, A., Verde, G., Vient, E., Vigilante, M., Wanlin, E., Wittwer, G., and Zucchini, A.

Subjects
Physics - Instrumentation and Detectors, Nuclear Experiment
Abstract

In this paper the technological aspects of the FAZIA array will be explored. After a productive commissioning phase, FAZIA blocks started to measure and give very useful data to explore the physics of Fermi energy heavy-ion reactions. This was possible thanks to many technical measures and innovations developed in the commissioning phase and tuned during the first experimental campaigns. This paper gives a detailed description of the present status of the FAZIA setup from the electronic and mechanical point of view, trying also to trace a path for new improvements and refinements of the apparatus., Comment: 17 pages, 9 figures

Published
2018
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11. Results of the ASY-EOS experiment at GSI: The symmetry energy at suprasaturation density

Author

Russotto, P., Gannon, S., Kupny, S., Lasko, P., Acosta, L., Adamczyk, M., Al-Ajlan, A., Al-Garawi, M., Al-Homaidhi, S., Amorini, F., Auditore, L., Aumann, T., Ayyad, Y., Basrak, Z., Benlliure, J., Boisjoli, M., Boretzky, K., Brzychczyk, J., Budzanowski, A., Caesar, C., Cardella, G., Cammarata, P., Chajecki, Z., Chartier, M., Chbihi, A., Colonna, M., Cozma, M. D., Czech, B., De Filippo, E., Di Toro, M., Famiano, M., Gašparić, I., Grassi, L., Guazzoni, C., Guazzoni, P., Heil, M., Heilborn, L., Introzzi, R., Isobe, T., Kezzar, K., Kiš, M., Krasznahorkay, A., Kurz, N., La Guidara, E., Lanzalone, G., Fèvre, A. Le, Leifels, Y., Lemmon, R. C., Li, Q. F., Lombardo, I., Lukasik, J., Lynch, W. G., Marini, P., Matthews, Z., May, L., Minniti, T., Mostazo, M., Pagano, A., Pagano, E. V., Papa, M., Pawlowski, P., Pirrone, S., Politi, G., Porto, F., Reviol, W., Riccio, F., Rizzo, F., Rosato, E., Rossi, D., Santoro, S., Sarantites, D. G., Simon, H., Skwirczynska, I., Sosin, Z., Stuhl, L., Trautmann, W., Trifirò, A., Trimarchi, M., Tsang, M. B., Verde, G., Veselsky, M., Vigilante, M., Wang, Yongjia, Wieloch, A., Wigg, P., Winkelbauer, J., Wolter, H. H., Wu, P., Yennello, S., Zambon, P., Zetta, L., and Zoric, M.

Subjects
Nuclear Experiment
Abstract

Directed and elliptic flows of neutrons and light charged particles were measured for the reaction 197Au+197Au at 400 MeV/nucleon incident energy within the ASY-EOS experimental campaign at the GSI laboratory. The detection system consisted of the Large Area Neutron Detector LAND, combined with parts of the CHIMERA multidetector, of the ALADIN Time-of-flight Wall, and of the Washington-University Microball detector. The latter three arrays were used for the event characterization and reaction-plane reconstruction. In addition, an array of triple telescopes, KRATTA, was used for complementary measurements of the isotopic composition and flows of light charged particles. From the comparison of the elliptic flow ratio of neutrons with respect to charged particles with UrQMD predictions, a value \gamma = 0.72 \pm 0.19 is obtained for the power-law coefficient describing the density dependence of the potential part in the parametrization of the symmetry energy. It represents a new and more stringent constraint for the regime of supra-saturation density and confirms, with a considerably smaller uncertainty, the moderately soft to linear density dependence deduced from the earlier FOPI-LAND data. The densities probed are shown to reach beyond twice saturation., Comment: 25 pages, 22 figures, accepted for publication in Physical Review C

Published
2016
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12. Tolerability of vortioxetine compared to selective serotonin reuptake inhibitors in older adults with major depressive disorder (VESPA): a randomised, assessor-blinded and statistician-blinded, multicentre, superiority trial

Author

Ostuzzi, G, Gastaldon, C, Tettamanti, M, Cartabia, M, Monti, I, Aguglia, A, Aguglia, E, Bartoli, F, Callegari, C, Canozzi, A, Carbone, E, Carrà, G, Caruso, R, Cavallotti, S, Chiappini, S, Colasante, F, Compri, B, D'Agostino, A, De Fazio, P, de Filippis, R, Gari, M, Ielmini, M, Ingrosso, G, Mammarella, S, Martinotti, G, Rodolico, A, Roncone, R, Sterzi, E, Tarsitani, L, Tiberto, E, Todini, L, Amaddeo, F, D'Avanzo, B, Barbato, A, Barbui, C, Alessi, M, Avincola, G, Bachi, B, Bernasconi, G, Birgillito, A, Bisso, E, Bonora, S, Calabrese, A, Callovini, T, Canestro, A, Canonico, S, Capogrosso, C, Carosielli, D, Caselli, I, Cavaleri, D, Cavallotto, C, Cesca, M, Chiarenza, C, Cioni, R, Coloccini, S, Cruciata, M, Cumerlato, C, De Filippis, R, De Palma, M, Del Vecchio, S, Della Rocca, B, Di Natale, C, D'Onofrio, E, Espa, I, Fior, G, Gancitano, M, Giordano, B, Giusti, L, Grassi, L, Guzzi, P, Isella, C, Lax, A, Marano, L, Marconi, F, Marella, M, Metelli, A, Michencig, G, Miuli, A, Moncada, A, Morello, P, Moretti, F, Morreale, M, Mosca, A, Nasti, C, Nosé, M, Ogheri, F, Oresti, M, Ornaghi, A, Palpella, D, Pancheri, C, Papola, D, Passeri, S, Pettorusso, M, Piacenti, S, Pinucci, I, Pugliese, V, Purgato, M, Rania, M, Robbi, F, Romito, S, Ronchi, B, Roselli, V, Segura-Garcia, C, Signorelli, M, Simonelli, G, Sociali, A, Sturiale, S, Tambelli, A, Todesco, B, Trabucco, A, Turrini, G, Villa, V, Wiedenmann, F, Zambuto, L, Zanini, E, Zannini, C, Zerbinati, L, Ostuzzi, Giovanni, Gastaldon, Chiara, Tettamanti, Mauro, Cartabia, Massimo, Monti, Igor, Aguglia, Andrea, Aguglia, Eugenio, Bartoli, Francesco, Callegari, Camilla, Canozzi, Andrea, Carbone, Elvira Anna, Carrà, Giuseppe, Caruso, Rosangela, Cavallotti, Simone, Chiappini, Stefania, Colasante, Fabrizio, Compri, Beatrice, D'Agostino, Armando, De Fazio, Pasquale, de Filippis, Renato, Gari, Matteo, Ielmini, Marta, Ingrosso, Gianmarco, Mammarella, Silvia, Martinotti, Giovanni, Rodolico, Alessandro, Roncone, Rita, Sterzi, Enrico, Tarsitani, Lorenzo, Tiberto, Elisa, Todini, Liliana, Amaddeo, Francesco, D'Avanzo, Barbara, Barbato, Angelo, Barbui, Corrado, Alessi, Maria Chiara, Avincola, Gabriele, Bachi, Bianca, Bernasconi, Gianna, Birgillito, Andrea, Bisso, Emanuele, Bonora, Stefano, Calabrese, Angela, Callovini, Tommaso, Canestro, Aurelia, Canonico, Salvo, Capogrosso, Chiara Alessandra, Carbone, Elvira, Carosielli, Doriana, Caselli, Ivano, Cavaleri, Daniele, Cavallotto, Clara, Cesca, Marco, Chiarenza, Cecilia, Cioni, Riccardo Matteo, Coloccini, Sara, Cruciata, Marco, Cumerlato, Claudia, De Filippis, Renato, De Palma, Manuela, Del Vecchio, Sasha, Della Rocca, Bianca, Di Natale, Chiara, D'Onofrio, Ettore, Espa, Irene, Fior, Giulia, Gancitano, Marta, Giordano, Barbara, Giusti, Laura, Grassi, Luigi, Guzzi, Pierluca, Isella, Celeste, Lax, Annamaria, Marano, Leonardo, Marconi, Federico, Marella, Marco, Metelli, Alessia, Michencig, Giulia, Miuli, Andrea, Moncada, Alessandro, Morello, Pietro, Moretti, Federico, Morreale, Marco, Mosca, Alessio, Nasti, Christian, Nosé, Michela, Ogheri, Filippo, Oresti, Margherita, Ornaghi, Alessandra, Palpella, Dario, Pancheri, Corinna, Papola, Davide, Passeri, Silvia, Pettorusso, Mauro, Piacenti, Susanna, Pinucci, Irene, Pugliese, Valentina, Purgato, Marianna, Rania, Marianna, Robbi, Federica, Romito, Samantha, Ronchi, Barbara, Roselli, Valentina, Segura-Garcia, Cristina, Signorelli, Maria Salvina, Simonelli, Gabriele, Sociali, Antonella, Sturiale, Serena, Tambelli, Antonio, Todesco, Beatrice, Trabucco, Alice, Turrini, Giulia, Villa, Veronica, Wiedenmann, Federico, Zambuto, Luca, Zanini, Elisa, Zannini, Chiara, Zerbinati, Luigi, Ostuzzi, G, Gastaldon, C, Tettamanti, M, Cartabia, M, Monti, I, Aguglia, A, Aguglia, E, Bartoli, F, Callegari, C, Canozzi, A, Carbone, E, Carrà, G, Caruso, R, Cavallotti, S, Chiappini, S, Colasante, F, Compri, B, D'Agostino, A, De Fazio, P, de Filippis, R, Gari, M, Ielmini, M, Ingrosso, G, Mammarella, S, Martinotti, G, Rodolico, A, Roncone, R, Sterzi, E, Tarsitani, L, Tiberto, E, Todini, L, Amaddeo, F, D'Avanzo, B, Barbato, A, Barbui, C, Alessi, M, Avincola, G, Bachi, B, Bernasconi, G, Birgillito, A, Bisso, E, Bonora, S, Calabrese, A, Callovini, T, Canestro, A, Canonico, S, Capogrosso, C, Carosielli, D, Caselli, I, Cavaleri, D, Cavallotto, C, Cesca, M, Chiarenza, C, Cioni, R, Coloccini, S, Cruciata, M, Cumerlato, C, De Filippis, R, De Palma, M, Del Vecchio, S, Della Rocca, B, Di Natale, C, D'Onofrio, E, Espa, I, Fior, G, Gancitano, M, Giordano, B, Giusti, L, Grassi, L, Guzzi, P, Isella, C, Lax, A, Marano, L, Marconi, F, Marella, M, Metelli, A, Michencig, G, Miuli, A, Moncada, A, Morello, P, Moretti, F, Morreale, M, Mosca, A, Nasti, C, Nosé, M, Ogheri, F, Oresti, M, Ornaghi, A, Palpella, D, Pancheri, C, Papola, D, Passeri, S, Pettorusso, M, Piacenti, S, Pinucci, I, Pugliese, V, Purgato, M, Rania, M, Robbi, F, Romito, S, Ronchi, B, Roselli, V, Segura-Garcia, C, Signorelli, M, Simonelli, G, Sociali, A, Sturiale, S, Tambelli, A, Todesco, B, Trabucco, A, Turrini, G, Villa, V, Wiedenmann, F, Zambuto, L, Zanini, E, Zannini, C, Zerbinati, L, Ostuzzi, Giovanni, Gastaldon, Chiara, Tettamanti, Mauro, Cartabia, Massimo, Monti, Igor, Aguglia, Andrea, Aguglia, Eugenio, Bartoli, Francesco, Callegari, Camilla, Canozzi, Andrea, Carbone, Elvira Anna, Carrà, Giuseppe, Caruso, Rosangela, Cavallotti, Simone, Chiappini, Stefania, Colasante, Fabrizio, Compri, Beatrice, D'Agostino, Armando, De Fazio, Pasquale, de Filippis, Renato, Gari, Matteo, Ielmini, Marta, Ingrosso, Gianmarco, Mammarella, Silvia, Martinotti, Giovanni, Rodolico, Alessandro, Roncone, Rita, Sterzi, Enrico, Tarsitani, Lorenzo, Tiberto, Elisa, Todini, Liliana, Amaddeo, Francesco, D'Avanzo, Barbara, Barbato, Angelo, Barbui, Corrado, Alessi, Maria Chiara, Avincola, Gabriele, Bachi, Bianca, Bernasconi, Gianna, Birgillito, Andrea, Bisso, Emanuele, Bonora, Stefano, Calabrese, Angela, Callovini, Tommaso, Canestro, Aurelia, Canonico, Salvo, Capogrosso, Chiara Alessandra, Carbone, Elvira, Carosielli, Doriana, Caselli, Ivano, Cavaleri, Daniele, Cavallotto, Clara, Cesca, Marco, Chiarenza, Cecilia, Cioni, Riccardo Matteo, Coloccini, Sara, Cruciata, Marco, Cumerlato, Claudia, De Filippis, Renato, De Palma, Manuela, Del Vecchio, Sasha, Della Rocca, Bianca, Di Natale, Chiara, D'Onofrio, Ettore, Espa, Irene, Fior, Giulia, Gancitano, Marta, Giordano, Barbara, Giusti, Laura, Grassi, Luigi, Guzzi, Pierluca, Isella, Celeste, Lax, Annamaria, Marano, Leonardo, Marconi, Federico, Marella, Marco, Metelli, Alessia, Michencig, Giulia, Miuli, Andrea, Moncada, Alessandro, Morello, Pietro, Moretti, Federico, Morreale, Marco, Mosca, Alessio, Nasti, Christian, Nosé, Michela, Ogheri, Filippo, Oresti, Margherita, Ornaghi, Alessandra, Palpella, Dario, Pancheri, Corinna, Papola, Davide, Passeri, Silvia, Pettorusso, Mauro, Piacenti, Susanna, Pinucci, Irene, Pugliese, Valentina, Purgato, Marianna, Rania, Marianna, Robbi, Federica, Romito, Samantha, Ronchi, Barbara, Roselli, Valentina, Segura-Garcia, Cristina, Signorelli, Maria Salvina, Simonelli, Gabriele, Sociali, Antonella, Sturiale, Serena, Tambelli, Antonio, Todesco, Beatrice, Trabucco, Alice, Turrini, Giulia, Villa, Veronica, Wiedenmann, Federico, Zambuto, Luca, Zanini, Elisa, Zannini, Chiara, and Zerbinati, Luigi

Abstract

Background: Major depressive disorder (MDD) is prevalent and disabling among older adults. Standing on its tolerability profile, vortioxetine might be a promising alternative to selective serotonin reuptake inhibitors (SSRIs) in such a vulnerable population. Methods: We conducted a randomised, assessor- and statistician-blinded, superiority trial including older adults with MDD. The study was conducted between 02/02/2019 and 02/22/2023 in 11 Italian Psychiatric Services. Participants were randomised to vortioxetine or one of the SSRIs, selected according to common practice. Treatment discontinuation due to adverse events after six months was the primary outcome, for which we aimed to detect a 12% difference in favour of vortioxetine. The study was registered in the online repository clinicaltrials.gov (NCT03779789). Findings: The intention-to-treat population included 179 individuals randomised to vortioxetine and 178 to SSRIs. Mean age was 73.7 years (standard deviation 6.1), and 264 participants (69%) were female. Of those on vortioxetine, 78 (44%) discontinued the treatment due to adverse events at six months, compared to 59 (33%) of those on SSRIs (odds ratio 1.56; 95% confidence interval 1.01–2.39). Adjusted and per-protocol analyses confirmed point estimates in favour of SSRIs, but without a significant difference. With the exception of the unadjusted survival analysis showing SSRIs to outperform vortioxetine, secondary outcomes provided results consistent with a lack of substantial safety and tolerability differences between the two arms. Overall, no significant differences emerged in terms of response rates, depressive symptoms and quality of life, while SSRIs outperformed vortioxetine in terms of cognitive performance. Interpretation: As opposed to what was previously hypothesised, vortioxetine did not show a better tolerability profile compared to SSRIs in older adults with MDD in this study. Additionally, hypothetical advantages of vortioxetine on depress

Published
2024

13. On the relativistic Lagrange-Laplace secular dynamics for extrasolar systems

Author

Sansottera, M., Grassi, L., and Giorgilli, A.

Subjects
Mathematics - Dynamical Systems, Astrophysics - Earth and Planetary Astrophysics
Abstract

We study the secular dynamics of extrasolar planetary systems by extending the Lagrange-Laplace theory to high order and by including the relativistic effects. We investigate the long-term evolution of the planetary eccentricities via normal form and we find an excellent agreement with direct numerical integrations. Finally we set up a simple analytic criterion that allows to evaluate the impact of the relativistic effects in the long-time evolution., Comment: 4 pages, 4 figures, Proceedings IAU Symposium No. S310 (Complex Planetary Systems)

Published
2015
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14. Dipolar degrees of freedom and Isospin equilibration processes in Heavy Ion collisions

Author

Papa, M., Berceanu, I., Acosta, L., Amorini, F., Agodi, C., Anzalone, A., Auditore, L., Cardella, G., Cavallaro, S., Chatterjee, M. B., De Filippo, E., Francalanza, L., Geraci, E., Grassi, L., Gnoffo, B., Han, J., La Guidara, E., Lanzalone, G., Lombardo, I., Pagano, C. Maiolino T. Minniti A., Pagano, E. V., Pirrone, S., Politi, G., Porto, F., Quattrocchi, L., Rizzo, F., Rosato, E., Russotto, P., Trifirò, A., Trimarchi, M., Verde, G., and Vigilante, M.

Subjects
Nuclear Experiment
Abstract

Background: In heavy ion collision at the Fermi energies Isospin equilibration processes occur- ring when nuclei with different charge/mass asymmetries interacts have been investigated to get information on the nucleon-nucleon Iso-vectorial effective interaction. Purpose: In this paper, for the system 48Ca +27 Al at 40 MeV/nucleon, we investigate on this process by means of an observable tightly linked to isospin equilibration processes and sensitive in exclusive way to the dynamical stage of the collision. From the comparison with dynamical model calculations we want also to obtain information on the Iso-vectorial effective microscopic interaction. Method: The average time derivative of the total dipole associated to the relative motion of all emitted charged particles and fragments has been determined from the measured charges and velocities by using the 4? multi-detector CHIMERA. The average has been determined for semi- peripheral collisions and for different charges Zb of the biggest produced fragment. Experimental evidences collected for the systems 27Al+48Ca and 27Al+40Ca at 40 MeV/nucleon used to support this novel method of investigation are also discussed., Comment: Submitted for publication on Phys. Rev. C. 0n 24-oct-2014

Published
2015
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15. Maladaptive coping styles moderate the relationship between information on cancer treatment and psychosocial symptoms: an Italian multicenter study.

Author

Zerbinati, L., Folesani, F., Caruso, R., Murri, M. Belvederi, Nanni, M. G., Righetti, S., Chiefari, L., Muscettola, A., Toffanin, T., Costantini, A., Zaccagnino, B., Ruffilli, F., and Grassi, L.

Abstract

Objectives: Disclosing information on diagnosis, prognosis and treatment is a delicate process in oncology, although awareness levels have over time increased in people with cancer. However, individual characteristics should be considered when communicating difficult information. We conducted a multicentric study to explore the moderating role of coping styles on the relationship between information about cancer, quality of life and psychological distress. Methods: In the period between October 2015 and February 2016, 288 patients with a diagnosis of a solid tumor were recruited from seven Italian oncology units. All participants were administered the Distress Thermometer (DT), the Mini-Mental Adjustment to Cancer (Mini-MAC), the European Organization for Research and Treatment of Cancer (EORTC) Core Quality of Life Questionnaire (QLQ-C30), and the EORTC QLQ 25-item information module (INFO25). We explored the moderating effect of coping style with quality of life (QoL) and distress (DT) as dependent variables and information on cancer treatment as independent variable. Results: Low levels of anxious preoccupation significantly moderated the relationship between information on treatment and QoL (R2 6%, p  <  0.001), while low and medium levels of hopelessness significantly moderated the relationship between information on treatment and DT (R2  =  14%, p  =  0.033). Adaptive coping strategies, such as fighting spirit and fatalism, and borderline strategies such as avoidance, did not play a role in this relationship. Conclusion: Taking into account and evaluating coping mechanisms in cancer care is a priority when disclosing information on treatments, in order to tailor communication style to individual features. [ABSTRACT FROM AUTHOR]

Published
2024
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16. Experimental Study of the Reaction in Classical Novae

Author

Meyer, A., de Séréville, N., Hammache, F., Adsley, P., Parikh, A., Assié, M., Assunção, M., Bastin, B., Beaumel, D., Béroff, K., Coc, Alain, D’Agata, G., Delafosse, C., De Oliveira, F., Flavigny, F., Fox, S. P., Georgiadou, A., Gottardo, A., Grassi, L., Guillot, J., Guimaräes, V., Hubbard, N., Id Barkach, T., Kiener, J., Laird, A. M., Lara, A. L., MacCormick, M., Matea, I., Olivier, L., Oulebsir, N., Perrot, L., Portail, C., Riley, J., Benítez, Á. M. Sánchez, Stefan, I., Tatischeff, V., Formicola, Alba, editor, Junker, Matthias, editor, Gialanella, Lucio, editor, and Imbriani, Gianluca, editor

Published
2019
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17. DETERMINATION OF IMPACT PARAMETERS IN ALIGNED BREAKUP OF PROJECTILE-LIKE FRAGMENTS IN Au-197+Au-197 COLLISIONS AT 23 A MeV

Author

Cap, T, Siwek-Wilczynska, K, Wilczynski, J, Amorini, F, Auditore, L, Cardella, G, De Filippo, E, Geraci, E, Grassi, L, Grzeszczuk, A, La Guidara, E, Han, J, Kozik, T, Lanzalone, G, Lombardo, I, Najman, R, Nicolis, NG, Pagano, A, Papa, M, Piasecki, E, Pirrone, S, Planeta, R, Politi, G, Rizzo, F, Russotto, P, Skwira-Chalot, I, Trifiro, A, Trimarchi, M, Verde, G, and Zipper, W

Subjects
Nuclear & Particles Physics, Mathematical Sciences, Physical Sciences
Published
2016

18. Determination of Impact Parameters in Aligned Breakup of Projectile-like Fragments in $^{197}$Au + $^{197}$Au Collisions at 23$A$\,MeV

Author

Cap, T, Siwek-Wilczyńska, K, Wilczyński, J, Amorini, F, Auditore, L, Cardella, G, De Filippo, E, Geraci, E, Grassi, L, Grzeszczuk, A, La Guidara, E, Han, J, Kozik, T, Lanzalone, G, Lombardo, I, Najman, R, Nicolis, NG, Pagano, A, Papa, M, Piasecki, E, Pirrone, S, Płaneta, R, Politi, G, Rizzo, F, Russotto, P, Skwira-Chalot, I, Trifiró, A, Trimarchi, M, Verde, G, and Zipper, W

Subjects
Mathematical Sciences, Physical Sciences, Nuclear & Particles Physics
Published
2016

20. Socioeconomic variations determine the clinical presentation, aetiology, and outcome of infective endocarditis: a prospective cohort study from the ESC-EORP EURO-ENDO (European Infective Endocarditis) registry

Author

Sengupta, S, Prendergast, B, Laroche, C, Furnaz, S, Ronderos, R, Almaghraby, A, Asch, F, Blechova, K, Zaky, H, Strahilevitz, J, Dworakowski, R, Miyasaka, Y, Sebag, I, Izumi, C, Axler, O, Jamiel, A, Philip, M, Vieira, M, Lancellotti, P, Habib, G, Gale, C, Beleslin, B, Budaj, A, Chioncel, O, Dagres, N, Danchin, N, Emberson, J, Erlinge, D, Glikson, M, Gray, A, Kayikcioglu, M, Maggioni, A, Nagy, V, Nedoshivin, A, Petronio, A, Roos-Hesselink, J, Wallentin, L, Zeymer, U, Cosyns, B, Donal, E, Erba, P, Iung, B, Popescu, B, Tornos, P, Andarala, M, Berle, C, Brunel-Lebecq, A, Fiorucci, E, Missiamenou, V, Taylor, C, Ali Tatar-Chentir, N, Al-Mallah, M, Astrom Aneq, M, Athanassopoulos, G, Badano, L, Benyoussef, S, Calderon Aranda, E, Cardim, N, Chan, K, Cruz, I, Edvardsen, T, Goliasch, G, Hagendorff, A, Hristova, K, Kamp, O, Kang, D, Kong, W, Matskeplishvili, S, Meshaal, M, Mirocevic, M, Neskovic, A, Pazdernik, M, Plonska-Gosciniak, E, Raissouni, M, Sade, L, Sadeghpour, A, Sambola, A, Separovic-Hanzevacki, J, Takeuchi, M, Tucay, E, Tude Rodrigues, A, Varga, A, Vaskelyte, J, Yamagata, K, Yiangou, K, Granada, I, Mahia, M, Ressi, S, Na-Cinovich, F, Iribarren, A, Fernandez Oses, P, Avegliano, G, Filipini, E, Obregon, R, Bangher, M, Dho, J, Cartasegna, L, Plastino, M, Novas, V, Shigel, C, Reyes, G, De Santos, M, Gastaldello, N, Granillo Fernandez, M, Potito, M, Streit-Enberger, G, Velazco, P, Casabe, J, Cortes, C, Guevara, E, Salmo, F, Seijo, M, Weidinger, F, Heger, M, Brooks, R, Stollberger, C, Ho, C, Perschy, L, Puskas, L, Binder, C, Rosenhek, R, Schneider, M, Winter, M, Hoffer, E, Melis-Sopoulou, M, Lecoq, E, Legrand, D, Jacquet, S, Massoz, M, Pierard, L, Marchetta, S, Dulgheru, R, D'Emal, C, Oury, C, Droog-Mans, S, Kerkhove, D, Plein, D, Soens, L, Weytjens, C, Motoc, A, Roosens, B, Lemoine, I, Rodrigus, I, Paelinck, B, Am-Sel, B, Unger, P, Konopnicki, D, Beauloye, C, Pasquet, A, Vanoverschelde, J, Pierard, S, Vancraeynest, D, Sinnaeve, F, Andrade, J, Staszko, K, Dos Santos Monteiro, R, Miglioranza, M, Shuha, D, Alcantara, M, Cravo, V, Fazzio, L, Felix, A, Iso, M, Musa, C, Siciliano, A, Villaca Filho, F, Rodrigues, A, Vilela, F, Braga, J, Silva, R, Rodrigues, D, Silva, L, Morhy, S, Fischer, C, Afonso, T, Abreu, J, Falcao, S, Moises, V, Gou-Vea, A, Mancuso, F, Souza, A, Silva, C, Joao, G, Abboud, C, Bellio de Mattos Barretto, R, Ramos, A, Arnoni, R, Assef, J, Della Togna, D, Le Bihan, D, Miglioli, L, Romero Oliveira, A, Tadeu Magro Kroll, R, Cortez, D, Gelape, C, Peirira Nunes, M, De Abreu Ferrari, T, Hay, K, Le, V, Page, M, Poulin, F, Sauve, C, Serri, K, Mercure, C, Beaudoin, J, Pibarot, P, Rudski, L, Ricafort, G, Barsic, B, Krajinovic, V, Vargovic, M, Lovric, D, Reskovic-Luksic, V, Vincelj, J, Jaksic Jurinjak, S, Yiannikourides, V, Ioannides, M, Pofaides, C, Masoura, V, Pudich, J, Linhart, A, Siranec, M, Marek, J, Kamenik, M, Pelouch, R, Coufal, Z, Mikulica, M, Griva, M, Jancova, E, Mikulcova, M, Taborsky, M, Precek, J, Jecmenova, M, Latal, J, Widimsky, J, Butta, T, Machacek, S, Vancata, R, Spinar, J, Holicka, M, Pow Chon Long, F, Anzules, N, Bajana Carpio, A, Largacha, G, Penaherrera, E, Moreira, D, Mahfouz, E, Elsafty, E, Soliman, A, Zayed, Y, Aboulenein, J, Abdel-Hay, M, Abdelnaby, M, Ahmed, M, Hammad, B, Saleh, Y, Zahran, H, El-Gebaly, O, Saad, A, Ali, M, Zeid, A, El Sharkawy, R, Al Kholy, A, Doss, R, Osama, D, Rizk, H, Elmogy, A, Mishriky, M, Assayag, P, El Hatimi, S, Hubert, S, Casalta, J, Gouriet, F, Arregle, F, Cammilleri, S, Tessonnier, L, Riberi, A, Botelho-Nevers, E, Gagneux-Brunon, A, Pierrard, R, Tulane, C, Campisi, S, Fuzellier, J, Detoc, M, Mehalla, T, Boutoille, D, Lecompte, A, Lefebvre, M, Pattier, S, Al Habash, O, Asseray-Madani, N, Biron, C, Brochard, J, Caillon, J, Cueff, C, Le Tourneau, T, Lecomte, R, Magali Michel, M, Orain, J, Delarue, S, Le Bras, M, Faucher, J, Aboyans, V, Bee-Harry, A, Durox, H, Lacoste, M, Magne, J, Mohty, D, David, A, Pradel, V, Sierra, V, Neykova, A, Bettayeb, B, Elkentaoui, S, Tzvetkov, B, Landry, G, Strady, C, Ainine, K, Baumard, S, Brasselet, C, Tassigny, C, Valente-Pires, V, Lefranc, M, Hoen, B, Lefevre, B, Curlier, E, Callier, C, Fourcade, N, Jobic, Y, Ansard, S, Le Berre, R, Le Ven, F, Pouliquen, M, Prat, G, Le Roux, P, Bouchart, F, Savoure, A, Alarcon, C, Chapuzet, C, Gueit, I, Tribouilloy, C, Bohbot, Y, Peugnet, F, Gun, M, Duval, X, Lescure, X, Ilic-Habensus, E, Sadoul, N, Selton-Suty, C, Alla, F, Goehringer, F, Huttin, O, Chevalier, E, Garcia, R, Le Marcis, V, Tattevin, P, Flecher, E, Revest, M, Chirouze, C, Bouiller, K, Hustache-Mathieu, L, Klopfenstein, T, Moreau, J, Fournier, D, Brunel, A, Lim, P, Oliver, L, Ternacle, J, Moussafeur, A, Chavanet, P, Piroth, L, Salmon-Rousseau, A, Buisson, M, Mahy, S, Martins, C, Go-Hier, S, Baumann, F, Lebras, S, Piper, C, Guckel, D, Borgermann, J, Horstkotte, D, Winkelmann, E, Brockmeier, B, Grey, D, Nick-Enig, G, Schueler, R, Ozturk, C, Stohr, E, Hamm, C, Walther, T, Brandt, R, Fruhauf, A, Hartung, C, Hellner, C, 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L., Jacobs-Orazi L., Mallia Azzopardi C., Xuereb R. G., Pis-Copo T., Farrugia J., Fenech M., Pllaha E., Vella C., Borg D., Casha R., Grib L., Raevschi E., Gre-Jdieru A., Kravcenco D., Prisacari E., Samohvalov E., Samohvalov S., Sceglova N., Panfle E., Cardaniuc L., Corcea V., Feodorovici A., Gaina V., Girbu L., Jimbei P., Balan G., Cardaniuc I., Benesco I., Marian V., Sumarga N., Bozovic B., Bulatovic N., Lakovic P., Music L., Budde R., Waha-Dat A., Gamela T., Meijers T., Van Melle J. P., Deursen V. M., Crijns H. J., Bekkers S. C., Cheriex E. C., Gilbers M., Kietselaer B. L., Knackstedt C., Lorusso R., Schalla S., Streukens S. A., Chamuleau S., Cramer M. -J., Teske A., Van der Spoel T., Wind A., Lokhorst J., Liesbek O., Van Heusden H., Tanis W., Van der Bilt I., Vriend J., De Lange-Van Bruggen H., Karijodikoro E., Riezebos R., van Dongen E., Schoep J., Stolk V., Offstad J. T., Beitnes J. O., Helle-Valle T., Skulstad H., Skardal R., Qamar N., Ahmed B., Butt M. H., Khanzada M. F., Saghir T., Wahid A., Hryniewiecki T., Szymanski P., Marzec K., Misztal-Ogonowska M., Kosmala W., Przewlocka-Kosmala M., Rojek A., Woznicka K., Zachwyc J., Lisowska A., Kamin-Ska M., Kasprzak J. D., Kowalczyk E., Strzecka D. F., Wejner-Mik P., Trabulo M., Freitas P., Ranchordas S., Rodrigues G., Pinto P., Queiros C., Azevedo J., Marques L., Seabra D., Branco L., Cruz M., Galrinho A., Moreira R., Rio P., Timoteo A. T., Selas M., Carmelo V., Duque Neves B., Pereira H., Guerra A., Marques A., Pintassilgo I., Tomescu M. C., Trofenciuc N. -M., Andor M., Bordejevic A., Branea H. S., Caruntu F., Velcean L. A., Mavrea A., Onel M. F., Parvanescu T., Pop D., Pop-Moldovan A. L., Puticiu M. I., Cirin L., Citu I. M., Cotoraci C. A., Darabantiu D., Farcas R., Marincu I., Ionac A., Cozma D., Mornos C., Goanta F., Popescu I., Beyer R., Mada R., Rancea R., Tomoaia R., Rosianu H., Stanescu C., Kobalava Z., Karaulova J., Ko-Tova E., Milto A., Pisaryuk A., Povalyaev N., Sorokina M., Alrahimi J., Elshiekh A., Ahmed A., Attia N., Putnikovic B., Dimic A., Ivanovic B., Matic S., Trifunovic D., Petrovic J., Kosevic D., Stojanovic I., Petrovic I., Dabic P., Milojevic P., Srdanovic I., Susak S., Velicki L., Vulin A., Kovacevic M., Redzek A., Stefanovic M., Yeo T. C., Kong W. K. F., Poh K. K., Vi-Lacosta I., Ferrera C., Olmos C., Abd El-Nasser M., Calvo Iglesias F., Bianco-Gonzalez E., Bravo Amaro M., Lopez-Rodriguez E., Lugo Adan J., Germinas A. N., Pazos-Lopez P., Pereira Loureiro M., Perez M. T., Raposeiras-Roubin S., Rasheed Yas S., Suarez-Varela M. -M., Vasallo Vidal F., Garcia-Dorado D., Fernandez-Hidalgo N., Gonzalez-Alujas T., Lozano J., Maisterra O., Pizzi N., Rios R., Bayes-Genis A., Pedro Botet L., Vallejo N., Llibre C., Mateu L., Nunez R., Quesada D., Berastegui E., Bosch Portell D., Aboal Vinas J., Albert Bertran X., Brugada Tar-Radellas R., Loma-Osorio Ricon P., Tiron de Llano C., Arnau M. A., Bel A., Blanes M., Osa A., Anguita M., Carrasco F., Castillo J. C., Zamorano J. L., Moya Mur J. L., Alvaro M., Fernandez-Golfin C., Monteagudo J. M., Navas Elorza E., Farinas Alvarez M. C., Aguero Balbin J., Zarauza J., Gutierrez-Diez J. F., Arminanzas C., Arnaiz de las Revillas F., Arnaiz Garcia A., Cobo Belaustegui M., Fernandez Sampedro M., Gutierrez Cuadra M., Garcia Cuello L., Gonzalez Rico C., Rodriguez-Alvarez R., Goikoetxea J., Montejo M., Miro J. M., Almela M., Ambrosioni J., Moreno A., Quintana E., Sandoval E., Tellez A., Tolosana J. M., Vidal B., Falces C., Fuster D., Garcia-De-la-Maria C., Hernandez-Meneses M., Llopis J., Marco F., Ruiz-Zamora I., Bardaji Ruiz A., Sanz Girgas E., Garcia-Pardo G., Guillen Marzo M., Rodriguez Oviedo A., Villares Jimenez A., Abid L., Ham-Mami R., Kammoun S., Mourali M. S., Mghaieth Zghal F., Ben Hlima M., Boudiche S., Ouali S., Zakhama L., Antit S., Slama I., Gulel O., Sahin M., Karacaglar E., Kucukoglu S., Cetinarslan O., Sinan U. Y., Canpolat U., Mutlu B., Atas H., Dervishova R., Ileri C., Alhashmi J., Tahir J., Zarger P., Baslib F., Woldman S., Menezes L., Primus C., Uppal R., Bvekerwa I., Chandrasekaran B., Kopanska A., Chambers J., Hancock J., Klein J., Rajani R., Ursi M. P., Cannata S., Fife A., Breeze J., Browne-Morgan M., Gunning M., Streather S., Zemedkun M., Alyavi B., Uzokov J., Sengupta, S, Prendergast, B, Laroche, C, Furnaz, S, Ronderos, R, Almaghraby, A, Asch, F, Blechova, K, Zaky, H, Strahilevitz, J, Dworakowski, R, Miyasaka, Y, Sebag, I, Izumi, C, Axler, O, Jamiel, A, Philip, M, Vieira, M, Lancellotti, P, Habib, G, Gale, C, Beleslin, B, Budaj, A, Chioncel, O, Dagres, N, Danchin, N, Emberson, J, Erlinge, D, Glikson, M, Gray, A, Kayikcioglu, M, Maggioni, A, Nagy, V, Nedoshivin, A, Petronio, A, Roos-Hesselink, J, Wallentin, L, Zeymer, U, Cosyns, B, Donal, E, Erba, P, Iung, B, Popescu, B, Tornos, P, Andarala, M, Berle, C, Brunel-Lebecq, A, Fiorucci, E, Missiamenou, V, Taylor, C, Ali Tatar-Chentir, N, Al-Mallah, M, Astrom Aneq, M, Athanassopoulos, G, Badano, L, Benyoussef, S, Calderon Aranda, E, Cardim, N, Chan, K, Cruz, I, Edvardsen, T, Goliasch, G, Hagendorff, A, Hristova, K, Kamp, O, Kang, D, Kong, W, Matskeplishvili, S, Meshaal, M, Mirocevic, M, Neskovic, A, Pazdernik, M, Plonska-Gosciniak, E, Raissouni, M, Sade, L, Sadeghpour, A, Sambola, A, Separovic-Hanzevacki, J, Takeuchi, M, Tucay, E, Tude Rodrigues, A, Varga, A, Vaskelyte, J, Yamagata, K, Yiangou, K, Granada, I, Mahia, M, Ressi, S, Na-Cinovich, F, Iribarren, A, Fernandez Oses, P, Avegliano, G, Filipini, E, Obregon, R, Bangher, M, Dho, J, Cartasegna, L, Plastino, M, Novas, V, Shigel, C, Reyes, G, De Santos, M, Gastaldello, N, Granillo Fernandez, M, Potito, M, Streit-Enberger, G, Velazco, P, Casabe, J, Cortes, C, Guevara, E, Salmo, F, Seijo, M, Weidinger, F, Heger, M, Brooks, R, Stollberger, C, Ho, C, Perschy, L, Puskas, L, Binder, C, Rosenhek, R, Schneider, M, Winter, M, Hoffer, E, Melis-Sopoulou, M, Lecoq, E, Legrand, D, Jacquet, S, Massoz, M, Pierard, L, Marchetta, S, Dulgheru, R, D'Emal, C, Oury, C, Droog-Mans, S, Kerkhove, D, Plein, D, Soens, L, Weytjens, C, Motoc, A, Roosens, B, Lemoine, I, Rodrigus, I, Paelinck, B, Am-Sel, B, Unger, P, Konopnicki, D, Beauloye, C, 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P., Prendergast B., Laroche C., Furnaz S., Ronderos R., Almaghraby A., Asch F. M., Blechova K., Zaky H., Strahilevitz J., Dworakowski R., Miyasaka Y., Sebag I., Izumi C., Axler O., Jamiel A., Philip M., Vieira M. L. C., Lancellotti P., Habib G., Gale C. P., Beleslin B., Budaj A., Chioncel O., Dagres N., Danchin N., Emberson J., Erlinge D., Glikson M., Gray A., Kayikcioglu M., Maggioni A. P., Nagy V. K., Nedoshivin A., Petronio A. -S., Roos-Hesselink J., Wallentin L., Zeymer U., Cosyns B., Donal E., Erba P., Iung B., Popescu B. A., Tornos P., Andarala M., Berle C., Brunel-Lebecq A., Fiorucci E., Missiamenou V., Taylor C., Ali Tatar-Chentir N. N., Al-Mallah M., Astrom Aneq M., Athanassopoulos G., Badano L. P., Benyoussef S., Calderon Aranda E., Cardim N. M., Chan K. -L., Cruz I., Edvardsen T., Goliasch G., Hagendorff A., Hristova K., Kamp O., Kang D. -H., Kong W., Matskeplishvili S., Meshaal M., Mirocevic M., Neskovic A. N., Pazdernik M., Plonska-Gosciniak E., Raissouni M., Sade L. E., Sadeghpour A., Sambola A., Separovic-Hanzevacki J., Takeuchi M., Tucay E., Tude Rodrigues A. C., Varga A., Vaskelyte J., Yamagata K., Yiangou K., Granada I., Mahia M., Ressi S., Na-Cinovich F., Iribarren A., Fernandez Oses P., Avegliano G., Filipini E., Obregon R., Bangher M., Dho J., Cartasegna L., Plastino M. L., Novas V., Shigel C., Reyes G., De Santos M., Gastaldello N., Granillo Fernandez M., Potito M., Streit-Enberger G., Velazco P., Casabe J. H., Cortes C., Guevara E., Salmo F., Seijo M., Weidinger F., Heger M., Brooks R., Stollberger C., Ho C. -Y., Perschy L., Puskas L., Binder C., Rosenhek R., Schneider M., Winter M. -P., Hoffer E., Melis-Sopoulou M., Lecoq E., Legrand D., Jacquet S., Massoz M., Pierard L., Marchetta S., Dulgheru R., D'Emal C., Oury C., Droog-Mans S., Kerkhove D., Plein D., Soens L., Weytjens C., Motoc A., Roosens B., Lemoine I., Rodrigus I., Paelinck B., Am-Sel B., Unger P., Konopnicki D., Beauloye C., Pasquet A., Vanoverschelde J. L., Pierard S., Vancraeynest D., Sinnaeve F., Andrade J. L., Staszko K., Dos Santos Monteiro R., Miglioranza M. H., Shuha D. L., Alcantara M., Cravo V., Fazzio L., Felix A., Iso M., Musa C., Siciliano A. P., Villaca Filho F., Rodrigues A., Vilela F., Braga J., Silva R., Rodrigues D., Silva L., Morhy S., Fischer C., Afonso T., Abreu J., Falcao S. N., Moises V. A., Gou-Vea A., Mancuso F. J., Souza A. C., Silva C. Y., Joao G., Abboud C. S., Bellio de Mattos Barretto R., Ramos A., Arnoni R., Assef J. E., Della Togna D. J., Le Bihan D., Miglioli L., Romero Oliveira A. P., Tadeu Magro Kroll R., Cortez D., Gelape C. L., Peirira Nunes M. D. C., De Abreu Ferrari T. C., Hay K., Le V., Page M., Poulin F., Sauve C., Serri K., Mercure C., Beaudoin J., Pibarot P., Rudski L. G., Ricafort G., Barsic B., Krajinovic V., Vargovic M., Lovric D., Reskovic-Luksic V., Vincelj J., Jaksic Jurinjak S., Yiannikourides V., Ioannides M., Pofaides C., Masoura V., Pudich J., Linhart A., Siranec M., Marek J., Kamenik M., Pelouch R., Coufal Z., Mikulica M., Griva M., Jancova E., Mikulcova M., Taborsky M., Precek J., Jecmenova M., Latal J., Widimsky J., Butta T., Machacek S., Vancata R., Spinar J., Holicka M., Pow Chon Long F., Anzules N., Bajana Carpio A., Largacha G., Penaherrera E., Moreira D., Mahfouz E., Elsafty E., Soliman A., Zayed Y., Aboulenein J., Abdel-Hay M., Abdelnaby M., Ahmed M., Hammad B., Saleh Y., Zahran H., El-Gebaly O., Saad A., Ali M., Zeid A., El Sharkawy R., Al Kholy A., Doss R., Osama D., Rizk H., Elmogy A., Mishriky M., Assayag P., El Hatimi S., Hubert S., Casalta J. -P., Gouriet F., Arregle F., Cammilleri S., Tessonnier L., Riberi A., Botelho-Nevers E., Gagneux-Brunon A., Pierrard R., Tulane C., Campisi S., Fuzellier J. -F., Detoc M., Mehalla T., Boutoille D., Lecompte A. S., Lefebvre M., Pattier S., Al Habash O., Asseray-Madani N., Biron C., Brochard J., Caillon J., Cueff C., Le Tourneau T., Lecomte R., Magali Michel M. M., Orain J., Delarue S., Le Bras M., Faucher J. -F., Aboyans V., Bee-Harry A., Durox H., Lacoste M., Magne J., Mohty D., David A., Pradel V., Sierra V., Neykova A., Bettayeb B., Elkentaoui S., Tzvetkov B., Landry G., Strady C., Ainine K., Baumard S., Brasselet C., Tassigny C., Valente-Pires V., Lefranc M., Hoen B., Lefevre B., Curlier E., Callier C., Fourcade N., Jobic Y., Ansard S., Le Berre R., Le Ven F., Pouliquen M. -C., Prat G., Le Roux P., Bouchart F., Savoure A., Alarcon C., Chapuzet C., Gueit I., Tribouilloy C., Bohbot Y., Peugnet F., Gun M., Duval X., Lescure X., Ilic-Habensus E., Sadoul N., Selton-Suty C., Alla F., Goehringer F., Huttin O., Chevalier E., Garcia R., Le Marcis V., Tattevin P., Flecher E., Revest M., Chirouze C., Bouiller K., Hustache-Mathieu L., Klopfenstein T., Moreau J., Fournier D., Brunel A. -S., Lim P., Oliver L., Ternacle J., Moussafeur A., Chavanet P., Piroth L., Salmon-Rousseau A., Buisson M., Mahy S., Martins C., Go-Hier S., Baumann F., Lebras S., Piper C., Guckel D., Borgermann J., Horstkotte D., Winkelmann E., Brockmeier B., Grey D., Nick-Enig G., Schueler R., Ozturk C., Stohr E., Hamm C., Walther T., Brandt R., Fruhauf A. -C., Hartung C. T., Hellner C., Wild C., Becker M., Hamada S., Kaestner W., Stangl K., Knebel F., Baldenhofer G., Brecht A., Dreger H., Isner C., Pfafflin F., Stegemann M., Zahn R., Fraiture B., Kilkowski C., Karcher A. -K., Klinger S., Tolksdorf H., Tousoulis D., Aggeli C., Sideris S., Venieri E., Sarri G., Tsiapras D., Armenis I., Koutsiari A., Floros G., Grassos C., Dragasis S., Rallidis L., Varlamos C., Michalis L., Naka K., Bechlioulis A., Kotsia A., Lakkas L., Pappas K., Papadopoulos C., Kiokas S., Lioni A., Misailidou S., Bar-Betseas J., Bonou M., Kapelios C., Tomprou I., Zerva K., Manolis A., Hamodraka E., Athanasiou D., Haralambidis G., Samaras H., Poulimenos L., Nagy A., Bartykowszki A., Gara E., Mungulmare K., Kasliwal R., Bansal M., Ranjan S., Bhan A., Kyavar M., Maleki M., Noohi Bezanjani F., Alizadehasl A., Boudagh S., Ghavidel A., Morad-Nejad P., Pasha H. R., Ghadrdoost B., Gilon D., Wanounou M., Israel S., d'Agostino C., Colonna P., De Michele L., Fumarola F., Stante M., Mar-Chionni N., Scheggi V., Alterini B., Del Pace S., Stefano P., Sparano C., Ruozi N., Tenaglia R., Muraru D., Limbruno U., Cresti A., Baratta P., Solari M., Giannattasio C., Moreo A., De Chiara B., Lopez Montero B., Musca F., Orcese C. A., Panzeri F., Spano F., Russo C. F., Alferi O., De Bonis M., Chiappetta S., Del Forno B., Ripa M., Scarpellini P., Tassan Din C., Castiglioni B., Pasci-Uta R., Carletti S., Ferrara D., Guffanti M., Iaci G., Lapenna E., Nisi T., Oltolini C., Busnardo E., Pajoro U., Agricola E., Meneghin R., Schiavi D., Piscione F., Citro R., Benvenga R. M., Greco L., Soriente L., Radano I., Prota C., Bellino M., Di Vece D., Santini F., Salsano A., Olivieri G. M., Turrini F., Messora R., Tondi S., Olaru A., Agnoletto V., Grassi L., Leonardi C., Sansoni S., Del Ponte S., Actis Dato G. M., De Martino A., Ohte N., Kikuchi S., Wakami K., Aonuma K., Seo Y., Ishizu T., Machino-Ohtsuka T., Yamamoto M., Iida N., Nakajima H., Nakagawa Y., Amano M., Miyake M., Takahashi K., Shiojima I., Maeba H., Suwa Y., Taniguchi N., Tsujimoto S., Kitai T., Ota M., Yuda S., Sasaki S., Hagiwara N., Yamazaki K., Ashihara K., Arai K., Saitou C., Saitou S., Suzuki G., Shibata Y., Watanabe N., Nishino S., Ashikaga K., Kuriyama N., Mahara K., Okubo T., Fujimaki H., Shi-Tan H., Yamamoto H., Abe K., Terada M., Takanashi S., Sata M., Yamada H., Kusunose K., Saijo Y., Seno H., Yuichiro O., Onishi T., Sera F., Nakatani S., Mizuno H., Sengoku K., Park S. W., Eun Kyoung K., Ga Yeon L., Hwang J. -W., Jin-Oh C., Park S. -J., Sang-Chol L., Sung-A C., Jang S. Y., Heo R., Lee S., Song J. -M., Jung E., Plisiene J., Dambrauskaite A., Gruodyte G., Jonkaitiene R., Mizariene V., Atkocaityte J., Zvirblyte R., Sow R., Codreanu A., Staub T., Michaux C., De la Vega E. C. L., Jacobs-Orazi L., Mallia Azzopardi C., Xuereb R. G., Pis-Copo T., Farrugia J., Fenech M., Pllaha E., Vella C., Borg D., Casha R., Grib L., Raevschi E., Gre-Jdieru A., Kravcenco D., Prisacari E., Samohvalov E., Samohvalov S., Sceglova N., Panfle E., Cardaniuc L., Corcea V., Feodorovici A., Gaina V., Girbu L., Jimbei P., Balan G., Cardaniuc I., Benesco I., Marian V., Sumarga N., Bozovic B., Bulatovic N., Lakovic P., Music L., Budde R., Waha-Dat A., Gamela T., Meijers T., Van Melle J. P., Deursen V. M., Crijns H. J., Bekkers S. C., Cheriex E. C., Gilbers M., Kietselaer B. L., Knackstedt C., Lorusso R., Schalla S., Streukens S. A., Chamuleau S., Cramer M. -J., Teske A., Van der Spoel T., Wind A., Lokhorst J., Liesbek O., Van Heusden H., Tanis W., Van der Bilt I., Vriend J., De Lange-Van Bruggen H., Karijodikoro E., Riezebos R., van Dongen E., Schoep J., Stolk V., Offstad J. T., Beitnes J. O., Helle-Valle T., Skulstad H., Skardal R., Qamar N., Ahmed B., Butt M. H., Khanzada M. F., Saghir T., Wahid A., Hryniewiecki T., Szymanski P., Marzec K., Misztal-Ogonowska M., Kosmala W., Przewlocka-Kosmala M., Rojek A., Woznicka K., Zachwyc J., Lisowska A., Kamin-Ska M., Kasprzak J. D., Kowalczyk E., Strzecka D. F., Wejner-Mik P., Trabulo M., Freitas P., Ranchordas S., Rodrigues G., Pinto P., Queiros C., Azevedo J., Marques L., Seabra D., Branco L., Cruz M., Galrinho A., Moreira R., Rio P., Timoteo A. T., Selas M., Carmelo V., Duque Neves B., Pereira H., Guerra A., Marques A., Pintassilgo I., Tomescu M. C., Trofenciuc N. -M., Andor M., Bordejevic A., Branea H. S., Caruntu F., Velcean L. A., Mavrea A., Onel M. F., Parvanescu T., Pop D., Pop-Moldovan A. L., Puticiu M. I., Cirin L., Citu I. M., Cotoraci C. A., Darabantiu D., Farcas R., Marincu I., Ionac A., Cozma D., Mornos C., Goanta F., Popescu I., Beyer R., Mada R., Rancea R., Tomoaia R., Rosianu H., Stanescu C., Kobalava Z., Karaulova J., Ko-Tova E., Milto A., Pisaryuk A., Povalyaev N., Sorokina M., Alrahimi J., Elshiekh A., Ahmed A., Attia N., Putnikovic B., Dimic A., Ivanovic B., Matic S., Trifunovic D., Petrovic J., Kosevic D., Stojanovic I., Petrovic I., Dabic P., Milojevic P., Srdanovic I., Susak S., Velicki L., Vulin A., Kovacevic M., Redzek A., Stefanovic M., Yeo T. C., Kong W. K. F., Poh K. K., Vi-Lacosta I., Ferrera C., Olmos C., Abd El-Nasser M., Calvo Iglesias F., Bianco-Gonzalez E., Bravo Amaro M., Lopez-Rodriguez E., Lugo Adan J., Germinas A. N., Pazos-Lopez P., Pereira Loureiro M., Perez M. T., Raposeiras-Roubin S., Rasheed Yas S., Suarez-Varela M. -M., Vasallo Vidal F., Garcia-Dorado D., Fernandez-Hidalgo N., Gonzalez-Alujas T., Lozano J., Maisterra O., Pizzi N., Rios R., Bayes-Genis A., Pedro Botet L., Vallejo N., Llibre C., Mateu L., Nunez R., Quesada D., Berastegui E., Bosch Portell D., Aboal Vinas J., Albert Bertran X., Brugada Tar-Radellas R., Loma-Osorio Ricon P., Tiron de Llano C., Arnau M. A., Bel A., Blanes M., Osa A., Anguita M., Carrasco F., Castillo J. C., Zamorano J. L., Moya Mur J. L., Alvaro M., Fernandez-Golfin C., Monteagudo J. M., Navas Elorza E., Farinas Alvarez M. C., Aguero Balbin J., Zarauza J., Gutierrez-Diez J. F., Arminanzas C., Arnaiz de las Revillas F., Arnaiz Garcia A., Cobo Belaustegui M., Fernandez Sampedro M., Gutierrez Cuadra M., Garcia Cuello L., Gonzalez Rico C., Rodriguez-Alvarez R., Goikoetxea J., Montejo M., Miro J. M., Almela M., Ambrosioni J., Moreno A., Quintana E., Sandoval E., Tellez A., Tolosana J. M., Vidal B., Falces C., Fuster D., Garcia-De-la-Maria C., Hernandez-Meneses M., Llopis J., Marco F., Ruiz-Zamora I., Bardaji Ruiz A., Sanz Girgas E., Garcia-Pardo G., Guillen Marzo M., Rodriguez Oviedo A., Villares Jimenez A., Abid L., Ham-Mami R., Kammoun S., Mourali M. S., Mghaieth Zghal F., Ben Hlima M., Boudiche S., Ouali S., Zakhama L., Antit S., Slama I., Gulel O., Sahin M., Karacaglar E., Kucukoglu S., Cetinarslan O., Sinan U. Y., Canpolat U., Mutlu B., Atas H., Dervishova R., Ileri C., Alhashmi J., Tahir J., Zarger P., Baslib F., Woldman S., Menezes L., Primus C., Uppal R., Bvekerwa I., Chandrasekaran B., Kopanska A., Chambers J., Hancock J., Klein J., Rajani R., Ursi M. P., Cannata S., Fife A., Breeze J., Browne-Morgan M., Gunning M., Streather S., Zemedkun M., Alyavi B., and Uzokov J.

Abstract

Aims Infective endocarditis (IE) is a life-threatening disease associated with high mortality and morbidity worldwide. We sought to determine how socioeconomic factors might influence its epidemiology, clinical presentation, investigation and management, and outcome, in a large international multicentre registry. Methods and results The EurObservational Programme (EORP) of the European Society of Cardiology EURO-ENDO (European Infective Endocarditis) registry comprises a prospective cohort of 3113 adult patients admitted for IE in 156 hospitals in 40 countries between January 2016 and March 2018. Patients were separated in three groups, according to World Bank economic stratification [group 1: high income (75.6%); group 2: upper-middle income (15.4%); group 3: lower-middle income (9.1%)]. Group 3 patients were younger [median age (interquartile range, IQR): group 1, 66 (53-75) years; group 2, 57 (41-68) years; group 3, 33 (26-43) years; P < 0.001] with a higher frequency of smokers, intravenous drug use, and human immunodeficiency virus infection (all P < 0.001) and presented later [median (IQR) days since symptom onset: group 1, 12 (3-35); group 2, 19 (6-54); group 3, 31 (12-62); P < 0.001] with a higher likelihood of developing congestive heart failure (13.6%, 11.1%, and 22.6%, respectively; P < 0.001) and persistent fever (9.8%, 14.2%, and 27.9%, respectively; P < 0.001). Among 2157 (69.3%) patients with theoretical indication for cardiac surgery, surgery was performed less frequently in group 3 patients (75.5%, 76.8%, and 51.3%, respectively; P < 0.001), who also demonstrated the highest mortality (15.0%, 23.0%, and 23.7%, respectively; P < 0.001). Conclusion Socioeconomic factors influence the clinical profile of patients presenting with IE across the world. Despite younger age, patients from the poorest countries presented with more frequent complications and higher mortality associated with delayed diagnosis and lower use of surgery.

Published
2023

21. Kinematical coincidence method in transfer reactions

Author

Acosta, L., Amorini, F., Auditore, L., Berceanu, I., Cardella, G., Chatterjiee, M. B., De Filippo, E., FrancalanzA, L., Gianì, R., Grassi, L., Grzeszczuk, A., La Guidara, E., Lanzalone, G., Lombardo, I., Loria, D., Minniti, T., Pagano, E. V., Papa, M., Pirrone, S., Politi, G., Pop, A., Porto, F., Rizzo, F., Rosato, E., Russotto, P., Santoro, S., Trifirò, A., Trimarchi, M., Verde, G., and Vigilante, M.

Subjects
Nuclear Experiment
Abstract

A new method to extract high resolution angular distributions from kinematical coincidence measurements in binary reactions is presented. Kinematic is used to extract the center of mass angular distribution from the measured energy spectrum of light particles. Results obtained in the case of 10Be+p-->9Be+d reaction measured with the CHIMERA detector are shown. An angular resolution of few degrees in the center of mass is obtained., Comment: 6 Page 10 Figures submitted to Nuclear Instruments and Methods A

Published
2012
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23. Correlations between isospin dynamics and Intermediate Mass Fragments emission time scales: a probe for the symmetry energy in asymmetric nuclear matter

Author

De Filippo, E., Amorini, F., Auditore, L., Baran, V., Berceanu, I., Cardella, G., Colonna, M., Geraci, E., Gianì, S., Grassi, L., Grzeszczuk, A., Guazzoni, P., Han, J., La Guidara, E., Lanzalone, G., Lombardo, I., Maiolino, C., Minniti, T., Pagano, A., Papa, M., Piasecki, E., Pirrone, S., Politi, G., Pop, A., Porto, F., Rizzo, F., Russotto, P., Santoro, S., Trifirò, A., Trimarchi, M., Verde, G., Vigilante, M., Wilczyński, J., and Zetta, L.

Subjects
Nuclear Experiment
Abstract

We show new data from the $^{64}$Ni+$^{124}$Sn and $^{58}$Ni+$^{112}$Sn reactions studied in direct kinematics with the CHIMERA detector at INFN-LNS and compared with the reverse kinematics reactions at the same incident beam energy (35 A MeV). Analyzing the data with the method of relative velocity correlations, fragments coming from statistical decay of an excited projectile-like (PLF) or target-like (TLF) fragments are discriminated from the ones coming from dynamical emission in the early stages of the reaction. By comparing data of the reverse kinematics experiment with a stochastic mean field (SMF) + GEMINI calculations our results show that observables from neck fragmentation mechanism add valuable constraints on the density dependence of symmetry energy. An indication is found for a moderately stiff symmetry energy potential term of EOS., Comment: Talk given by E. De Filippo at the 11th International Conference on Nucleus-Nucleus Collisions (NN2012), San Antonio, Texas, USA, May 27-June 1, 2012. To appear in the NN2012 Proceedings in Journal of Physics: Conference Series (JPCS)

Published
2012
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24. The ASY-EOS experiment at GSI: investigating the symmetry energy at supra-saturation densities

Author

Russotto, P., Chartier, M., De Filippo, E., Févre, A. Le, Gannon, S., Gašparić, I., Kiš, M., Kupny, S., Leifels, Y., Lemmon, R. C., Łukasik, J., Marini, P., Pagano, A., Pawłowski, P., Santoro, S., Trautmann, W., Veselsky, M., Acosta, L., Adamczyk, M., Al-Ajlan, A., Al-Garawi, M., Al-Homaidhi, S., Amorini, F., Auditore, L., Aumann, T., Ayyad, Y., Baran, V., Basrak, Z., Benlliure, J., Boiano, C., Boisjoli, M., Boretzky, K., Brzychczyk, J., Budzanowski, A., Cardella, G., Cammarata, P., Chajecki, Z., Chbihi, A., Colonna, M., Cozma, D., Czech, B., Di Toro, M., Famiano, M., Geraci, E., Greco, V., Grassi, L., Guazzoni, C., Guazzoni, P., Heil, M., Heilborn, L., Introzzi, R., Isobe, T., Kezzar, K., Krasznahorkay, A., Kurz, N., La Guidara, E., Lanzalone, G., Lasko, P., Li, Q., Lombardo, I., Lynch, W. G., Matthews, Z., May, L., Minniti, T., Mostazo, M., Papa, M., Pirrone, S., Politi, G., Porto, F., Reifarth, R., Reisdorf, W., Riccio, F., Rizzo, F., Rosato, E., Rossi, D., Simon, H., Skwirczynska, I., Sosin, Z., Stuhl, L., Trifiró, A., Trimarchi, M., Tsang, M. B., Verde, G., Vigilante, M., Wieloch, A., Wigg, P., Wolter, H. H., Wu, P., Yennello, S., Zambon, P., Zetta, L., and Zoric, M.

Subjects
Nuclear Experiment
Abstract

The elliptic-flow ratio of neutrons with respect to protons in reactions of neutron rich heavy-ions systems at intermediate energies has been proposed as an observable sensitive to the strength of the symmetry term in the nuclear Equation Of State (EOS) at supra-saturation densities. The recent results obtained from the existing FOPI/LAND data for $^{197}$Au+$^{197}$Au collisions at 400 MeV/nucleon in comparison with the UrQMD model allowed a first estimate of the symmetry term of the EOS but suffer from a considerable statistical uncertainty. In order to obtain an improved data set for Au+Au collisions and to extend the study to other systems, a new experiment was carried out at the GSI laboratory by the ASY-EOS collaboration in May 2011., Comment: Talk given by P. Russotto at the 11th International Conference on Nucleus-Nucleus Collisions (NN2012), San Antonio, Texas, USA, May 27-June 1, 2012. To appear in the NN2012 Proceedings in Journal of Physics: Conference Series (JPCS)

Published
2012
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25. Status of the small-sized telescopes programme for the Cherenkov Telescope Array Observatory

Author

Marshall, Heather K., Spyromilio, Jason, Usuda, Tomonori, Trois, A., Douneaux, J., Scuderi, S., White, R., Tagliaferri, G., Proserpio, L., Tosti, G., Bruno, P., Cailleux, J., Conforti, V., El Mouden, A., De Frondat, F., Gargano, C., Germani, S., Gianotti, F., Giavitto, G., Giordano, V., Grassi, L., Iovenitti, S., Laporte, P., La Palombara, N., Lessio, L., Leto, G., Marchetti, A., Millul, R., Molfese, C., Russo, F., Saturni, F., Sironi, G., Antonelli, A., Funk, S., Hinton, J., Pareschi, G., Sol, H., Able, M., Attinà, P., Barcelo, M., Baryshev, A., Chadwick, P, Depaoli, D., Einecke, S., Lapington, J., Lee, S., Okumura, A., Rol, E., Rowell, G., Schaefer, J., Sofia, I., Tajima, H., Watson, J., Wohlleben, F., Zanmar Sanchez, R., Zink, A., Balbo, M., Bang, S., Bekema, M., Bellassai, G., Berge, D., Bigongiari, C., Bonnoli, G., Brown, A., Bulgarelli, A., Cappi, M., Caraveo, P., Cotter, G., Cristofari, P., Falceta-Gonçalves, D., De Gouveia Dal Pino, E., De Simone, N., del Valle, M. V., Fermino, C., Giuliani, A., Greenshaw, T., Kowal, G., Lloyd, S., Lombardi, S., Lucarelli, F., Martinetti, E., Mineo, T., Nayak, A., Oughton, W., Penno, M., Righi, C., Ross, D., Rulten, C., Santos-Lima, R., Schwab, B., Sliusar, V., Stamerra, A., Takahashi, M., Tavecchio, F., Vecchi, M., Vercellone, S., Vink, J., Walter, R., Zampieri, L., and Zech, A.

Published
2024
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26. Identity and divergence of protein domain architectures after the Yeast Whole Genome Duplication event

Author

Fusco, D., Grassi, L., Sellerio, A. L., Cora`, D., Bassetti, B., Caselle, M., and Lagomarsino, M. Cosentino

Subjects
Quantitative Biology - Genomics, Quantitative Biology - Biomolecules
Abstract

Analyzing the properties of duplicate genes during evolution is useful to understand the development of new cell functions. The yeast S. cerevisiae is a useful testing ground for this problem, because its duplicated genes with different evolutionary birth and destiny are well distinguishable. In particular, there is a clear detection for the occurrence of a Whole Genome Duplication (WGD) event in S. cerevisiae, and the genes derived from this event (WGD paralogs) are known. We studied WGD and non-WGD duplicates by two parallel analysis based on structural protein domains and on Gene Ontology annotation scheme respectively. The results show that while a large number of ``duplicable'' structural domains is shared in local and global duplications, WGD and non-WGD paralogs tend to have different functions. The reason for this is the existence of WGD and non-WGD specific domains with largely different functions. In agreement with the recent findings of Wapinski and collaborators (Nature 449, 2007), WGD paralogs often perform ``core'' cell functions, such as translation and DNA replication, while local duplications associate with ``peripheral'' functions such as response to stress. Our results also support the fact that domain architectures are a reliable tool to detect homology, as the domains of duplicates are largely invariant with date and nature of the duplication, while their sequences and also their functions might migrate., Comment: 19 pages, 5 figures, Supporting Information

Published
2008

27. Isospin Dependence of Incomplete Fusion Reactions at 25 Mev/a

Author

Amorini, F., Cardella, G., Giuliani, G., Papa, M., Agodi, C., Alba, R., Anzalone, A., Berceanu, I., Cavallaro, S., Chatterjee, M. B., Coniglione, R., De Filippo, E., Di Pietro, A., Geraci, E., Grassi, L., Grzeszczuk, A., Figuera, P., La Guidara, E., Lanzalone, G., Neindre, N. Le, Lombardo, I., Maiolino, C., Pagano, A., Pirrone, S., Politi, G., Pop, A., Porto, F., Rizzo, F., Russotto, P., Santonocito, D., Sapienza, P., and Verde, G.

Subjects
Nuclear Experiment
Abstract

40Ca+40,48Ca,46Ti reactions at 25 MeV/A have been studied using the 4p CHIMERA detector. An isospin effect on the competition between incomplete fusion and dissipative binary reaction mechanisms has been observed. The probability of producing a compound system is observed to be lower in the case of N=Z colliding systems as compared to the case of reactions induced on the more neutron rich 48Ca target. Predictions based on CoMD-II calculations show that the competition between fusion-like and dissipative reactions, for the selected centrality, can strongly constraint the parameterization of symmetry energy and its density dependence in the nuclear equation of state., Comment: 4 pages 3 figures submitted to phys.rew.Lett

Published
2008
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28. The Two Loop Crossed Ladder Vertex Diagram with Two Massive Exchanges

Author

Aglietti, U., Bonciani, R., Grassi, L., and Remiddi, E.

Subjects
High Energy Physics - Phenomenology
Abstract

We compute the (three) master integrals for the crossed ladder diagram with two exchanged quanta of equal mass. The differential equations obeyed by the master integrals are used to generate power series expansions centered around all the singular (plus some regular) points, which are then matched numerically with high accuracy. The expansions allow a fast and precise numerical calculation of the three master integrals (better than 15 digits with less than 30 terms in the whole real axis). A conspicuous relation with the equal-mass sunrise in two dimensions is found. Comparison with a previous large momentum expansion is made finding complete agreement., Comment: 42 pages, 1 figure

Published
2007
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29. OSCAR: A new modular device for the identification and correlation of low energy particles

Author

Dell’Aquila, D., Lombardo, I., Verde, G., Vigilante, M., Ausanio, G., Ordine, A., Miranda, M., De Luca, M., Alba, R., Augey, L., Barlini, S., Bonnet, E., Borderie, B., Bougault, R., Bruno, M., Camaiani, A., Casini, G., Chbihi, A., Cicerchia, M., Cinausero, M., Fabris, D., Faible, Q., Francalanza, L., Frankland, J.D., Grassi, L., Gramegna, F., Gruyer, D., Kordyasz, A.J., Kozik, T., LaTorre, R., Le Neindre, N., Lopez, O., Marchi, T., Morelli, L., Ottanelli, P., Parlog, M., Pastore, G., Pasquali, G., Piantelli, S., Santonocito, D., Stefanini, A.A., Tortone, G., Valdrè, S., and Vient, E.

Published
2018
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33. THE STRONG ROLE OF N/Z DEGREE OF FREEDOM IN Ca plus Ca REACTIONS AT 25 MeV/NUCLEON

Author

Lombardo, I, Agodi, C, Amorini, F, Anzalone, A, Auditore, L, Berceanu, I, Cardella, G, Cavallaro, S, DeFilippo, E, Giuliani, G, Geraci, E, Grassi, L, Han, J, LaGuidara, E, Lanzalone, G, Loria, D, Maiolino, C, Pagano, A, Papa, M, Pirrone, S, Politi, G, Porto, F, Rizzo, F, Russotto, P, Trifiro, A, Trimarchi, M, Verde, G, and Vigilante, M

Subjects
Mathematical Sciences, Physical Sciences, Nuclear & Particles Physics, Mathematical sciences, Physical sciences
Published
2011

34. Benchmarking the PreSPEC@GSI experiment for Coulex-multipolarimetry on the π(p3/2)→π(p1/2)85Br spin-flip transition in π(p3/2)→π(p1/2)85Br

Author

Napiralla, P., Lettmann, M., Stahl, C., Rainovski, G., Pietralla, N., Afara, S., Ameil, F., Arici, T., Aydin, S., Barrientos, D., Bednarczyk, P., Bentley, M. A., Benzoni, G., Birkenbach, B., Blazhev, A., Boston, A. J., Boutachkov, P., Bracco, A., Bruyneel, B., Clément, E., Cortés, M. L., Crespi, F. C. L., Cullen, D. M., Curien, D., Désesquelles, P., Didierjean, F., Domingo-Pardo, C., Duchêne, G., Eberth, J., Egger, H., Fahlander, C., Gerl, J., Gladnishki, K. A., Golubev, P., González, V., Górska, M., Gottardo, A., Grassi, L., Habermann, T., Harkness-Brennan, L. J., Hess, H., Jenkins, D. G., John, P. R., Jolie, J., Judson, D. S., Kojouharov, I., Korten, W., Labiche, M., Lalović, N., Lizarazo, C., Louchart-Henning, C., Maj, A., Menegazzo, R., Mengoni, D., Merchan, E., Million, B., Möller, O., Möller, T., Moschner, K., Modamio, V., Napoli, D., Singh, B. S. Nara, Podolyák, Zs., Pietri, S., Ralet, D., Reese, M., Reiter, P., Rudolph, D., Sanchis, E., Sarmiento, L. G., Schaffner, H., Simpson, J., Singh, P. P., Valiente-Dobón, J. J., Werner, V., and Wieland, O.

Published
2020
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35. Invertible Quadratic Non-Linear Layers for MPC-/FHE-/ZK-Friendly Schemes over Fnp

Author

Grassi, L., Onofri, S., Pedicini, M., and Sozzi, L.

Subjects
Computational Mathematics, Poseidon, Applied Mathematics, Non-Linear Layer, Digital Security, MPC/FHE/ZK-Friendly Schemes, Multiplicative Complexity, Software, Computer Science Applications
Abstract

Motivated by new applications such as secure Multi-Party Computation (MPC), Fully Homomorphic Encryption (FHE), and Zero-Knowledge proofs (ZK), many MPC-, FHE- and ZK-friendly symmetric-key primitives that minimize the number of multiplications over Fp for a large prime p have been recently proposed in the literature. This goal is often achieved by instantiating the non-linear layer via power maps x↦xd. In this paper, we start an analysis of new non-linear permutation functions over Fnp that can be used as building blocks in such symmetrickey primitives. Given a local map F : Fmp→ Fp, we limit ourselves to focus on S-Boxes over Fnp for n ≥ m defined as SF (x0, x1, . . . , xn−1) = y0|y1| . . . |yn−1 where yi := F(xi, xi+1, . . . , xi+m−1). As main results, we prove that• given any quadratic function F : F2p→ Fp, the corresponding S-Box SF over Fnp for n ≥ 3 is never invertible;• similarly, given any quadratic function F : F3p → Fp, the corresponding S-Box SF over Fnp for n ≥ 5 is never invertible.Moreover, for each p ≥ 3, we present (1st) generalizations of the Lai-Massey construction over Fnp defined as before via functions F : Fmp → Fp for each n = m ≥ 2 and (2nd) (non-trivial) quadratic functions F : F3p → Fp such that SF over Fnp for n ∈ {3, 4} is invertible. As an open problem for future work, we conjecture that for each m ≥ 1 there exists a finite integer nmax(m) such that SF over Fnp defined as before via a quadratic function F : Fmp →Fp is not invertible for each n ≥ nmax(m). Finally, as a concrete application, we propose Neptune, a variant of the sponge hash function Poseidon, whose non-linear layer is designed by taking into account the results presented in this paper. We show that this variant leads to a concrete multiplication reduction with respect to Poseidon.

Published
2022

36. Experimental Study of the $${^{30}}{\text {P}({\text {p}}}{,}{\upgamma })^{31}\text {S}$$ Reaction in Classical Novae

Author

Meyer, A., primary, de Séréville, N., additional, Hammache, F., additional, Adsley, P., additional, Parikh, A., additional, Assié, M., additional, Assunção, M., additional, Bastin, B., additional, Beaumel, D., additional, Béroff, K., additional, Coc, Alain, additional, D’Agata, G., additional, Delafosse, C., additional, De Oliveira, F., additional, Flavigny, F., additional, Fox, S. P., additional, Georgiadou, A., additional, Gottardo, A., additional, Grassi, L., additional, Guillot, J., additional, Guimaräes, V., additional, Hubbard, N., additional, Id Barkach, T., additional, Kiener, J., additional, Laird, A. M., additional, Lara, A. L., additional, MacCormick, M., additional, Matea, I., additional, Olivier, L., additional, Oulebsir, N., additional, Perrot, L., additional, Portail, C., additional, Riley, J., additional, Benítez, Á. M. Sánchez, additional, Stefan, I., additional, and Tatischeff, V., additional

Published
2019
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37. Characteristics, management, and outcomes of patients with left-sided infective endocarditis complicated by heart failure: a substudy of the ESC-EORP EURO-ENDO (European infective endocarditis) registry

Author

Bohbot, Y, Habib, G, Laroche, C, Stohr, E, Chirouze, C, Hernandez-Meneses, M, Melissopoulou, M, Mutlu, B, Scheggi, V, Branco, L, Olmos, C, Reyes, G, Pazdernik, M, Iung, B, Sow, R, Mirocevic, M, Lancellotti, P, Tribouilloy, C, Gale, C, Beleslin, B, Budaj, A, Chioncel, O, Dagres, N, Danchin, N, Emberson, J, Erlinge, D, Glikson, M, Gray, A, Kayikcioglu, M, Maggioni, A, Nagy, V, Nedoshivin, A, Petronio, A, Roos-Hesselink, J, Wallentin, L, Zeymer, U, Cosyns, B, Donal, E, Erba, P, Popescu, B, Prendergast, B, Tornos, P, Andarala, M, Berle, C, Brunel-Lebecq, A, Fiorucci, E, Missiamenou, V, Taylor, C, Ali Tatar-Chentir, N, Al-Mallah, M, Astrom Aneq, M, Athanassopoulos, G, Badano, L, Benyoussef, S, Calderon Aranda, E, Cardim, N, Chan, K, Cruz, I, Edvardsen, T, Goliasch, G, Hagendorff, A, Hristova, K, Kamp, O, Kang, D, Kong, W, Matskeplishvili, S, Meshaal, M, Neskovic, A, Plonska-Gosciniak, E, Raissouni, M, Ronderos, R, Sade, L, Sadeghpour, A, Sambola, A, Sengupta, S, Separovic-Hanzevacki, J, Takeuchi, M, Tucay, E, Tude Rodrigues, A, Varga, A, Vaskelyte, J, Yamagata, K, Yiangou, K, Zaky, H, Granada, I, Mahia, M, Ressi, S, Nacinovich, F, Iribarren, A, Fernandez Oses, P, Avegliano, G, Filipini, E, Obregon, R, Bangher, M, Dho, J, Cartasegna, L, Plastino, M, Novas, V, Shigel, C, De Santos, M, Gastaldello, N, Granillo Fernandez, M, Potito, M, Streitenberger, G, Velazco, P, Casabe, J, Cortes, C, Guevara, E, Salmo, F, Seijo, M, Weidinger, F, Heger, M, Brooks, R, Stollberger, C, Ho, C, Perschy, L, Puskas, L, Binder, C, Rosenhek, R, Schneider, M, Winter, M, Hoffer, E, Lecoq, E, Legrand, D, Jacquet, S, Massoz, M, Pierard, L, Marchetta, S, Dulgheru, R, D'Emal, C, Oury, C, Droogmans, S, Kerkhove, D, Plein, D, Soens, L, Weytjens, C, Motoc, A, Roosens, B, Lemoine, I, Rodrigus, I, Paelinck, B, Amsel, B, Unger, P, Konopnicki, D, Beauloye, C, Pasquet, A, Vanoverschelde, J, Pierard, S, Vancraeynest, D, Sinnaeve, F, Andrade, J, Staszko, K, Dos Santos Monteiro, R, Miglioranza, M, Shuha, D, Alcantara, M, Cravo, V, Fazzio, L, Felix, A, Iso, M, Musa, C, Siciliano, A, Villaca Filho, F, Rodrigues, A, Vilela, F, Braga, J, Silva, R, Rodrigues, D, Silva, L, Morhy, S, Fischer, C, Vieira, M, Afonso, T, Abreu, J, Falcao, S, Moises, V, Gouvea, A, Mancuso, F, Souza, A, Silva, C, Joao, G, Abboud, C, Bellio de Mattos Barretto, R, Ramos, A, Arnoni, R, Assef, J, Della Togna, D, Le Bihan, D, Miglioli, L, Romero Oliveira, A, Tadeu Magro Kroll, R, Cortez, D, Gelape, C, Peirira Nunes, M, De Abreu Ferrari, T, Hay, K, Le, V, Page, M, Poulin, F, Sauve, C, Serri, K, Mercure, C, Beaudoin, J, Pibarot, P, Sebag, I, Rudski, L, Ricafort, G, Barsic, B, Krajinovic, V, Vargovic, M, Lovric, D, Reskovic-Luksic, V, Vincelj, J, Jaksic Jurinjak, S, Yiannikourides, V, Ioannides, M, Pofaides, C, Masoura, V, Pudich, J, Linhart, A, Siranec, M, Marek, J, Blechova, K, Kamenik, M, Pelouch, R, Coufal, Z, Mikulica, M, Griva, M, Jancova, E, Mikulcova, M, Taborsky, M, Precek, J, Jecmenova, M, Latal, J, Widimsky, J, Butta, T, Machacek, S, Vancata, R, Spinar, J, Holicka, M, Pow Chon Long, F, Anzules, N, Bajana Carpio, A, Largacha, G, Penaherrera, E, Moreira, D, Mahfouz, E, Elsafty, E, Soliman, A, Zayed, Y, Aboulenein, J, Abdel-Hay, M, Almaghraby, A, Abdelnaby, M, Ahmed, M, Hammad, B, Saleh, Y, Zahran, H, Elgebaly, O, Saad, A, Ali, M, Zeid, A, El Sharkawy, R, Al Kholy, A, Doss, R, Osama, D, Rizk, H, Elmogy, A, Mishriky, M, Assayag, P, El Hatimi, S, Hubert, S, Casalta, J, Gouriet, F, Arregle, F, Cammilleri, S, Tessonnier, L, Riberi, A, Botelho-Nevers, E, Gagneux-Brunon, A, Pierrard, R, Tulane, C, Campisi, S, Fuzellier, J, Detoc, M, Mehalla, T, Boutoille, D, Lecompte, A, Lefebvre, M, Pattier, S, Al Habash, O, Asseray-Madani, N, Biron, C, Brochard, J, Caillon, J, Cueff, C, Le Tourneau, T, Lecomte, R, Magali Michel, M, Orain, J, Delarue, S, Le Bras, M, Faucher, J, Aboyans, V, Beeharry, A, Durox, H, Lacoste, M, Magne, J, Mohty, D, David, A, Pradel, V, Sierra, V, Neykova, A, Bettayeb, B, Elkentaoui, S, Tzvetkov, B, Landry, G, Strady, C, Ainine, K, Baumard, S, Brasselet, C, Tassigny, C, Valente-Pires, V, Lefranc, M, Hoen, B, Lefevre, B, Curlier, E, Callier, C, Fourcade, N, Jobic, Y, Ansard, S, Le Berre, R, Le Ven, F, Pouliquen, M, Prat, G, Le Roux, P, Bouchart, F, Savoure, A, Alarcon, C, Chapuzet, C, Gueit, I, Peugnet, F, Gun, M, Duval, X, Lescure, X, Ilic-Habensus, E, Sadoul, N, Selton-Suty, C, Alla, F, Goehringer, F, Huttin, O, Chevalier, E, Garcia, R, Le Marcis, V, Tattevin, P, Flecher, E, Revest, M, Bouiller, K, Hustache-Mathieu, L, Klopfenstein, T, Moreau, J, Fournier, D, Brunel, A, Lim, P, Oliver, L, Ternacle, J, Moussafeur, A, Chavanet, P, Piroth, L, Salmon-Rousseau, A, Buisson, M, Mahy, S, Martins, C, Gohier, S, Axler, O, Baumann, F, Lebras, S, Piper, C, Guckel, D, Borgermann, J, Horstkotte, D, Winkelmann, E, Brockmeier, B, Grey, D, Nickenig, G, Schueler, R, Ozturk, C, Hamm, C, Walther, T, Brandt, R, Fruhauf, A, Hartung, C, Hellner, C, Wild, C, Becker, M, Hamada, S, Kaestner, W, Stangl, K, Knebel, F, Baldenhofer, G, Brecht, A, Dreger, H, Isner, C, Pfafflin, F, Stegemann, M, Zahn, R, Fraiture, B, Kilkowski, C, Karcher, A, Klinger, S, Tolksdorf, H, Tousoulis, D, Aggeli, C, Sideris, S, Venieri, E, Sarri, G, Tsiapras, D, Armenis, I, Koutsiari, A, Floros, G, Grassos, C, Dragasis, S, Rallidis, L, Varlamos, C, Michalis, L, Naka, K, Bechlioulis, A, Kotsia, A, Lakkas, L, Pappas, K, Papadopoulos, C, Kiokas, S, Lioni, A, Misailidou, S, Barbetseas, J, Bonou, M, Kapelios, C, Tomprou, I, Zerva, K, Manolis, A, Hamodraka, E, Athanasiou, D, Haralambidis, G, Samaras, H, Poulimenos, L, Nagy, A, Bartykowszki, A, Gara, E, Mungulmare, K, Kasliwal, R, Bansal, M, Ranjan, S, Bhan, A, Kyavar, M, Maleki, M, Bezanjani, F, Alizadehasl, A, Boudagh, S, Ghavidel, A, Moradnejad, P, Pasha, H, Ghadrdoost, B, Gilon, D, Strahilevitz, J, Wanounou, M, Israel, S, D'Agostino, C, Colonna, P, De Michele, L, Fumarola, F, Stante, M, Marchionni, N, Alterini, B, Del Pace, S, Stefano, P, Sparano, C, Ruozi, N, Tenaglia, R, Muraru, D, Limbruno, U, Cresti, A, Baratta, P, Solari, M, Giannattasio, C, Moreo, A, De Chiara, B, Lopez Montero, B, Musca, F, Orcese, C, Panzeri, F, Spano, F, Russo, C, Alfieri, O, De Bonis, M, Chiappetta, S, Del Forno, B, Ripa, M, Scarpellini, P, Tassan Din, C, Castiglioni, B, Pasciuta, R, Carletti, S, Ferrara, D, Guffanti, M, Iaci, G, Lapenna, E, Nisi, T, Oltolini, C, Busnardo, E, Pajoro, U, Agricola, E, Meneghin, R, Schiavi, D, Piscione, F, Citro, R, Benvenga, R, Greco, L, Soriente, L, Radano, I, Prota, C, Bellino, M, Di Vece, D, Santini, F, Salsano, A, Olivieri, G, Turrini, F, Messora, R, Tondi, S, Olaru, A, Agnoletto, V, Grassi, L, Leonardi, C, Sansoni, S, Del Ponte, S, Actis Dato, G, De Martino, A, Ohte, N, Kikuchi, S, Wakami, K, Aonuma, K, Seo, Y, Ishizu, T, Machino-Ohtsuka, T, Yamamoto, M, Iida, N, Nakajima, H, Nakagawa, Y, Izumi, C, Amano, M, Miyake, M, Takahashi, K, Shiojima, I, Miyasaka, Y, Maeba, H, Suwa, Y, Taniguchi, N, Tsujimoto, S, Kitai, T, Ota, M, Yuda, S, Sasaki, S, Hagiwara, N, Yamazaki, K, Ashihara, K, Arai, K, Saitou, C, Saitou, S, Suzuki, G, Shibata, Y, Watanabe, N, Nishino, S, Ashikaga, K, Kuriyama, N, Mahara, K, Okubo, T, Fujimaki, H, Shitan, H, Yamamoto, H, Abe, K, Terada, M, Takanashi, S, Sata, M, Yamada, H, Kusunose, K, Saijo, Y, Seno, H, Yuichiro, O, Onishi, T, Sera, F, Nakatani, S, Mizuno, H, Sengoku, K, Park, S, Kyoung, K, Yeon, L, Hwang, J, Jin-Oh, C, Sang-Chol, L, Sung-A, C, Jang, S, Heo, R, Lee, S, Song, J, Jung, E, Plisiene, J, Dambrauskaite, A, Gruodyte, G, Jonkaitiene, R, Mizariene, V, Atkocaityte, J, Zvirblyte, R, Codreanu, A, Staub, T, Michaux, C, De la Vega, E, Jacobs-Orazi, L, Mallia Azzopardi, C, Xuereb, R, Piscopo, T, Farrugia, J, Fenech, M, Pllaha, E, Vella, C, Borg, D, Casha, R, Grib, L, Raevschi, E, Grejdieru, A, Kravcenco, D, Prisacari, E, Samohvalov, E, Samohvalov, S, Sceglova, N, Panfile, E, Cardaniuc, L, Corcea, V, Feodorovici, A, Gaina, V, Girbu, L, Jimbei, P, Balan, G, Cardaniuc, I, Benesco, I, Marian, V, Sumarga, N, Bozovic, B, Bulatovic, N, Lakovic, P, Music, L, Budde, R, Wahadat, A, Gamela, T, Meijers, T, Van Melle, J, Deursen, V, Crijns, H, Bekkers, S, Cheriex, E, Gilbers, M, Kietselaer, B, Knackstedt, C, Lorusso, R, Schalla, S, Streukens, S, Chamuleau, S, Cramer, M, Teske, A, Van der Spoel, T, Wind, A, Lokhorst, J, Liesbek, O, Van Heusden, H, Tanis, W, Van der Bilt, I, Vriend, J, De Lange-van Bruggen, H, Karijodikoro, E, Riezebos, R, van Dongen, E, Schoep, J, Stolk, V, Offstad, J, Beitnes, J, Helle-Valle, T, Skulstad, H, Skardal, R, Qamar, N, Furnaz, S, Ahmed, B, Butt, M, Khanzada, M, Saghir, T, Wahid, A, Hryniewiecki, T, Szymanski, P, Marzec, K, Misztal-Ogonowska, M, Kosmala, W, Przewlocka-Kosmala, M, Rojek, A, Woznicka, K, Zachwyc, J, Lisowska, A, Kaminska, M, Kasprzak, J, Kowalczyk, E, Strzecka, D, Wejner-Mik, P, Trabulo, M, Freitas, P, Ranchordas, S, Rodrigues, G, Pinto, P, Queiros, C, Azevedo, J, Marques, L, Seabra, D, Cruz, M, Galrinho, A, Moreira, R, Rio, P, Timoteo, A, Selas, M, Carmelo, V, Duque Neves, B, Pereira, H, Guerra, A, Marques, A, Pintassilgo, I, Tomescu, M, Trofenciuc, N, Andor, M, Bordejevic, A, Branea, H, Caruntu, F, Velcean, L, Mavrea, A, Onel, M, Parvanescu, T, Pop, D, Pop-Moldovan, A, Puticiu, M, Cirin, L, Citu, I, Cotoraci, C, Darabantiu, D, Farcas, R, Marincu, I, Ionac, A, Cozma, D, Mornos, C, Goanta, F, Popescu, I, Beyer, R, Mada, R, Rancea, R, Tomoaia, R, Rosianu, H, Stanescu, C, Kobalava, Z, Karaulova, J, Kotova, E, Milto, A, Pisaryuk, A, Povalyaev, N, Sorokina, M, Alrahimi, J, Elshiekh, A, Jamiel, A, Ahmed, A, Attia, N, Putnikovic, B, Dimic, A, Ivanovic, B, Matic, S, Trifunovic, D, Petrovic, J, Kosevic, D, Stojanovic, I, Petrovic, I, Dabic, P, Milojevic, P, Srdanovic, I, Susak, S, Velicki, L, Vulin, A, Kovacevic, M, Redzek, A, Stefanovic, M, Yeo, T, Poh, K, Vilacosta, I, Ferrera, C, Abd El- Nasser, M, Calvo Iglesias, F, Blanco-Gonzalez, E, Bravo Amaro, M, Lopez-Rodriguez, E, Lugo Adan, J, Germinas, A, Pazos-Lopez, P, Pereira Loureiro, M, Perez, M, Raposeiras-Roubin, S, Rasheed Yas, S, Suarez-Varela, M, Vasallo Vidal, F, Garcia-Dorado, D, Fernandez-Hidalgo, N, Gonzalez-Alujas, T, Lozano, J, Maisterra, O, Pizzi, N, Rios, R, Bayes-Genis, A, Pedro Botet, L, Vallejo, N, Llibre, C, Mateu, L, Nunez, R, Quesada, D, Berastegui, E, Bosch Portell, D, Aboal Vinas, J, Albert Bertran, X, Brugada Tarradellas, R, Loma-Osorio Ricon, P, Tiron de Llano, C, Arnau, M, Bel, A, Blanes, M, Osa, A, Anguita, M, Carrasco, F, Castillo, J, Zamorano, J, Moya Mur, J, Alvaro, M, Fernandez-Golfin, C, Monteagudo, J, Navas Elorza, E, Farinas Alvarez, M, Aguero Balbin, J, Zarauza, J, Gutierrez-Diez, J, Arminanzas, C, Arnaiz de las Revillas, F, Arnaiz Garcia, A, Cobo Belaustegui, M, Fernandez Sampedro, M, Gutierrez Cuadra, M, Garcia Cuello, L, Gonzalez Rico, C, Rodriguez-Alvarez, R, Goikoetxea, J, Montejo, M, Miro, J, Almela, M, Ambrosioni, J, Moreno, A, Quintana, E, Sandoval, E, Tellez, A, Tolosana, J, Vidal, B, Falces, C, Fuster, D, 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R., Ghadrdoost B., Gilon D., Strahilevitz J., Wanounou M., Israel S., d'Agostino C., Colonna P., De Michele L., Fumarola F., Stante M., Marchionni N., Alterini B., Del Pace S., Stefano P., Sparano C., Ruozi N., Tenaglia R., Muraru D., Limbruno U., Cresti A., Baratta P., Solari M., Giannattasio C., Moreo A., De Chiara B., Lopez Montero B., Musca F., Orcese C. A., Panzeri F., Spano F., Russo C. F., Alfieri O., De Bonis M., Chiappetta S., Del Forno B., Ripa M., Scarpellini P., Tassan Din C., Castiglioni B., Pasciuta R., Carletti S., Ferrara D., Guffanti M., Iaci G., Lapenna E., Nisi T., Oltolini C., Busnardo E., Pajoro U., Agricola E., Meneghin R., Schiavi D., Piscione F., Citro R., Benvenga R. M., Greco L., Soriente L., Radano I., Prota C., Bellino M., Di Vece D., Santini F., Salsano A., Olivieri G. M., Turrini F., Messora R., Tondi S., Olaru A., Agnoletto V., Grassi L., Leonardi C., Sansoni S., Del Ponte S., Actis Dato G. 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L., Jacobs-Orazi L., Mallia Azzopardi C., Xuereb R. G., Piscopo T., Farrugia J., Fenech M., Pllaha E., Vella C., Borg D., Casha R., Grib L., Raevschi E., Grejdieru A., Kravcenco D., Prisacari E., Samohvalov E., Samohvalov S., Sceglova N., Panfile E., Cardaniuc L., Corcea V., Feodorovici A., Gaina V., Girbu L., Jimbei P., Balan G., Cardaniuc I., Benesco I., Marian V., Sumarga N., Bozovic B., Bulatovic N., Lakovic P., Music L., Budde R., Wahadat A., Gamela T., Meijers T., Van Melle J. P., Deursen V. M., Crijns H. J., Bekkers S. C., Cheriex E. C., Gilbers M., Kietselaer B. L., Knackstedt C., Lorusso R., Schalla S., Streukens S. A., Chamuleau S., Cramer M. -J., Teske A., Van der Spoel T., Wind A., Lokhorst J., Liesbek O., Van Heusden H., Tanis W., Van der Bilt I., Vriend J., De Lange-van Bruggen H., Karijodikoro E., Riezebos R., van Dongen E., Schoep J., Stolk V., Offstad J. T., Beitnes J. O., Helle-Valle T., Skulstad H., Skardal R., Qamar N., Furnaz S., Ahmed B., Butt M. H., Khanzada M. F., Saghir T., Wahid A., Hryniewiecki T., Szymanski P., Marzec K., Misztal-Ogonowska M., Kosmala W., Przewlocka-Kosmala M., Rojek A., Woznicka K., Zachwyc J., Lisowska A., Kaminska M., Kasprzak J. D., Kowalczyk E., Strzecka D. F., Wejner-Mik P., Trabulo M., Freitas P., Ranchordas S., Rodrigues G., Pinto P., Queiros C., Azevedo J., Marques L., Seabra D., Cruz M., Galrinho A., Moreira R., Rio P., Timoteo A. T., Selas M., Carmelo V., Duque Neves B., Pereira H., Guerra A., Marques A., Pintassilgo I., Tomescu M. C., Trofenciuc N. -M., Andor M., Bordejevic A., Branea H. S., Caruntu F., Velcean L. A., Mavrea A., Onel M. F., Parvanescu T., Pop D., Pop-Moldovan A. L., Puticiu M. I., Cirin L., Citu I. M., Cotoraci C. 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Abstract

Aims: To evaluate the current management and survival of patients with left-sided infective endocarditis (IE) complicated by congestive heart failure (CHF) in the ESC-EORP European Endocarditis (EURO-ENDO) registry. Methods and results: Among the 3116 patients enrolled in this prospective registry, 2449 (mean age: 60 years, 69% male) with left-sided (native or prosthetic) IE were included in this study. Patients with CHF (n = 698, 28.5%) were older, with more comorbidity and more severe valvular damage (mitro-aortic involvement, vegetations >10 mm and severe regurgitation/new prosthesis dehiscence) than those without CHF (all p ≤ 0.019). Patients with CHF experienced higher 30-day and 1-year mortality than those without (20.5% vs. 9.0% and 36.1% vs. 19.3%, respectively) and CHF remained strongly associated with 30-day (odds ratio[OR] 2.37, 95% confidence interval [CI] [1.73–3.24; p < 0.001) and 1-year mortality (hazard ratio [HR] 1.69, 95% CI 1.39–2.05; p < 0.001) after adjustment for established outcome predictors, including early surgery, or after propensity matching for age, sex, and comorbidity (n = 618 [88.5%] for each group, both p < 0.001). Early surgery, performed on 49% of these patients with IE complicated by CHF, remained associated with a substantial reduction in 30-day mortality following multivariable analysis, after adjustment for age, sex, Charlson comorbidity index, cerebrovascular accident, Staphylococcus aureus IE, streptococcal IE, uncontrolled infection, vegetation size >10 mm, severe valvular regurgitation and/or new prosthetic dehiscence, perivalvular complication, and prosthetic IE (OR 0.22, 95% CI 0.12–0.38; p < 0.001) and in 1-year mortality (HR 0.29, 95% CI 0.20–0.41; p < 0.001). Conclusion: Congestive heart failure is common in left-sided IE and is associated with older age, greater comorbidity, more advanced lesions, and markedly higher 30-day and 1-year mortality. Early surgery is strongly associated with lower mort

Published
2022

38. Correction to: Surgery and outcome of infective endocarditis in octogenarians: prospective data from the ESC EORP EURO-ENDO registry (Infection, (2022), 50, 5, (1191-1202), 10.1007/s15010-022-01792-0)

Author

Pazdernik M., Pazdernik, M, Iung, B, Mutlu, B, Alla, F, Riezebos, R, Kong, W, Nunes, M, Pierard, L, Srdanovic, I, Yamada, H, De Martino, A, Miglioranza, M, Magne, J, Piper, C, Laroche, C, Maggioni, A, Lancellotti, P, Habib, G, Selton-Suty, C, Ronderos, R, Avegliano, G, Oses, P, Filipini, E, Granada, I, Iribarren, A, Mahia, M, Nacinovich, F, Ressi, S, Obregon, R, Bangher, M, Dho, J, Cartasegna, L, Plastino, M, Novas, V, Shigel, C, Reyes, G, De Santos, M, Gastaldello, N, Fernandez, M, Potito, M, Streitenberger, G, Velazco, P, Casabe, J, Cortes, C, Guevara, E, Salmo, F, Seijo, M, Weidinger, F, Heger, M, Brooks, R, Stollberger, C, Ho, C, Perschy, L, Puskas, L, Goliasch, G, Binder, C, Rosenhek, R, Schneider, M, Winter, M, Hoffer, E, Melissopoulou, M, Lecoq, E, Legrand, D, Jacquet, S, Massoz, M, Dulgheru, R, Marchetta, S, D'Emal, C, Oury, C, Cosyns, B, Droogmans, S, Kerkhove, D, Motoc, A, Plein, D, Roosens, B, Soens, L, Weytjens, C, Lemoine, I, Rodrigus, I, Paelinck, B, Amsel, B, Unger, P, Konopnicki, D, Beauloye, C, Pasquet, A, Pierard, S, Vancraeynest, D, Vanoverschelde, J, Sinnaeve, F, Andrade, J, Rodrigues, A, Staszko, K, Dos Santos Monteiro, R, Shuha, D, Alcantara, M, Cravo, V, Fazzio, L, Felix, A, Iso, M, Musa, C, Siciliano, A, Filho, F, Braga, J, Silva, R, Vilela, F, Rodrigues, D, Silva, L, Morhy, S, Fischer, C, Vieira, M, Afonso, T, Abreu, J, Falcao, S, Moises, V, Gouvea, A, Joao, G, Mancuso, F, Silva, C, Souza, A, Abboud, C, de Mattos Barretto, R, Ramos, A, Arnoni, R, Assef, J, Togna, D, Le Bihan, D, Miglioli, L, Oliveira, A, Kroll, R, Cortez, D, Gelape, C, De Abreu Ferrari, T, Chan, K, Hay, K, Le, V, Page, M, Poulin, F, Sauve, C, Serri, K, Mercure, C, Beaudoin, J, Pibarot, P, Sebag, I, Rudski, L, Ricafort, G, Barsic, B, Krajinovic, V, Vargovic, M, Separovic-Hanzevacki, J, Lovric, D, Reskovic-Luksic, V, Vincelj, J, Jurinjak, S, Yiannikourides, V, Ioannides, M, Kyriakou, C, Pofaides, C, Masoura, V, Yiangou, K, Pudich, J, Linhart, A, Siranec, M, Marek, J, 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L., Michaux C., Staub T., Jacobs-Orazi L., Azzopardi C. M., Xuereb R. G., Piscopo T., Borg D., Casha R., Farrugia J., Fenech M., Pllaha E., Vella C., Yamagata K., Grib L., Raevschi E., Grejdieru A., Balan G., Cardaniuc I., Cardaniuc L., Corcea V., Feodorovici A., Gaina V., Girbu L., Jimbei P., Kravcenco D., Panfile E., Prisacari E., Samohvalov E., Samohvalov S., Sceglova N., Benesco I., Marian V., Sumarga N., Mirocevic M., Bozovic B., Bulatovic N., Lakovic P., Music L., Roos-Hesselink J., Budde R., Gamela T., Wahadat A., Kamp O., Meijers T., Van Melle J. P., Deursen V. M., Crijns H., Bekkers S., Cheriex E., Gilbers M., Kietselaer B., Knackstedt C., Lorusso R., Schalla S., Streukens S., Chamuleau S., Cramer M. -J., Teske A., Van der Spoel T., Wind A., Liesbek O., Lokhorst J., Van Heusden H., Tanis W., Van der Bilt I., Vriend J., De Lange-van Bruggen H., Karijodikoro E., van Dongen E., Schoep J., Stolk V., Axler O., Baumann F., Lebras S., Edvardsen T., Offstad J. T., Beitnes J. O., Helle-Valle T., Skulstad H., Skardal R., Qamar N., Furnaz S., Ahmed B., Butt M. H., Khanzada M. F., Saghir T., Wahid A., Hryniewiecki T., Szymanski P., Marzec K., Misztal-Ogonowska M., Kosmala W., Przewlocka-Kosmala M., Rojek A., Woznicka K., Zachwyc J., Lisowska A., Kaminska M., Kasprzak J., Kowalczyk E., Strzecka D. F., Wejner-Mik P., Trabulo M., Freitas P., Ranchordas S., Rodrigues G., Pinto P., Queiros C., Azevedo J., Marques L., Seabra D., Branco L., Cruz M., Galrinho A., Moreira R., Rio P., Timoteo A. T., Selas M., Cardim N. M., Carmelo V., Neves B. D., Pereira H., Cruz I., Guerra A., Marques A., Pintassilgo I., Tomescu M. C., Trofenciuc N. -M., Andor M., Bordejevic A., Branea H. S., Caruntu F., Cirin L., Citu I. M., Cotoraci C. A., Darabantiu D., Farcas R., Marincu I., Mavrea A., Onel M. F., Parvanescu T., Pop D., Pop-Moldovan A. L., Puticiu M. I., Velcean L. A., Ionac A., Cozma D., Mornos C., Goanta F., Popescu I., Beyer R., Mada R., Rancea R., Rosianu H., Tomoaia R., Stanescu C., Kobalava Z., Karaulova J., Kotova E., Milto A., Pisaryuk A., Povalyaev N., Sorokina M., Alrahimi J., Elshiekh A., Jamiel A., Ahmed A., Al-Mallah M., Attia N., Putnikovic B., Neskovic A., Dimic A., Ivanovic B., Matic S., Trifunovic D., Petrovic J., Kosevic D., Dabic P., Milojevic P., Petrovic I., Stojanovic I., Kovacevic M., Redzek A., Stefanovic M., Susak S., Velicki L., Vulin A., Yeo T. C., Kong W. K. F., Poh K. K., Vilacosta I., El-Nasser M. A., Ferrera C., Olmos C., Iglesias F. C., Blanco-Gonzalez E., Amaro M. B., Germinas A. N., Lopez-Rodriguez E., Adan J. L., Pazos-Lopez P., Loureiro M. P., Perez M. T., Raposeiras-Roubin S., Yas S. R., Suarez-Varela M. -M., Vidal F. V., Garcia-Dorado D., Sambola A., Fernandez-Hidalgo N., Gonzalez-Alujas T., Lozano J., Maisterra O., Pizzi N., Rios R., Tornos P., Bayes-Genis A., Botet L. P., Vallejo N., Berastegui E., Llibre C., Mateu L., Nunez R., Quesada D., Portell D. B., Vinas J. A., Bertran X. A., Tarradellas R. B., Ricon P. L. -O., de Llano C. T., Arnau M. A., Bel A., Blanes M., Osa A., Anguita M., Carrasco F., Castillo J., Zamorano J. L., Mur J. L. M., Alvaro M., Fernandez-Golfin C., Monteagudo J. M., Elorza E. N., Alvarez M. C. F., Balbin J. A., Arminanzas C., de las Revillas F. A., Garcia A. A., Belaustegui M. C., Sampedro M. F., Cuadra M. G., Gutierrez-Diez J. F., Zarauza J., Cuello L. G., Rico C. G., Rodriguez-Alvarez R., Goikoetxea J., Montejo M., Miro J., Almela M., Ambrosioni J., Falces C., Fuster D., Garcia-de-la-Maria C., Hernandez-Meneses M., Llopis J., Marco F., Moreno A., Quintana E., Sandoval E., Tellez A., Tolosana J. M., Vidal B., Ruiz-Zamora I., Ruiz A. B., Girgas E. S., Garcia-Pardo G., Marzo M. G., Oviedo A. R., Jimenez A. V., Abid L., Hammami R., Kammoun S., Mourali M. S., Zghal F. M., Hlima M. B., Boudiche S., Ouali S., Zakhama L., Antit S., Slama I., Gulel O., Sahin M., Sade L. E., Karacaglar E., Kucukoglu S., Cetinarslan O., Sinan U. Y., Canpolat U., Atas H., Dervishova R., Ileri C., Zaky H., Alhashmi J., Baslib F., Tahir J., Zarger P., Woldman S., Menezes L., Primus C., Uppal R., Bvekerwa I., Chandrasekaran B., Kopanska A., Prendergast B., Cannata S., Chambers J., Hancock J., Klein J., Rajani R., Ursi M. P., Dworakowski R., Fife A., Breeze J., Browne-Morgan M., Gunning M., Streather S., Asch F., Zemedkun M., Alyavi B., and Uzokov J.

Published
2022

39. Surgery and outcome of infective endocarditis in octogenarians: prospective data from the ESC EORP EURO-ENDO registry

Author

Pazdernik, M, Iung, B, Mutlu, B, Alla, F, Riezebos, R, Kong, W, Nunes, M, Pierard, L, Srdanovic, I, Yamada, H, De Martino, A, Miglioranza, M, Magne, J, Piper, C, Laroche, C, Maggioni, A, Lancellotti, P, Habib, G, Selton-Suty, C, Ronderos, R, Avegliano, G, Oses, P, Filipini, E, Granada, I, Iribarren, A, Mahia, M, Nacinovich, F, Ressi, S, Obregon, R, Bangher, M, Dho, J, Cartasegna, L, Plastino, M, Novas, V, Shigel, C, Reyes, G, De Santos, M, Gastaldello, N, Fernandez, M, Potito, M, Streitenberger, G, Velazco, P, Casabe, J, Cortes, C, Guevara, E, Salmo, F, Seijo, M, Weidinger, F, Heger, M, Brooks, R, Stollberger, C, Ho, C, Perschy, L, Puskas, L, Goliasch, G, Binder, C, Rosenhek, R, Schneider, M, Winter, M, Hoffer, E, Melissopoulou, M, Lecoq, E, Legrand, D, Jacquet, S, Massoz, M, Dulgheru, R, Marchetta, S, Demal, C, Oury, C, Cosyns, B, Droogmans, S, Kerkhove, D, Motoc, A, Plein, D, Roosens, B, Soens, L, Weytjens, C, Lemoine, I, Rodrigus, I, Paelinck, B, Amsel, B, Unger, P, Konopnicki, D, Beauloye, C, Pasquet, A, Pierard, S, Vancraeynest, D, Vanoverschelde, J, Sinnaeve, F, Andrade, J, Rodrigues, A, Staszko, K, Dos Santos Monteiro, R, Shuha, D, Alcantara, M, Cravo, V, Fazzio, L, Felix, A, Iso, M, Musa, C, Siciliano, A, Filho, F, Braga, J, Silva, R, Vilela, F, Rodrigues, D, Silva, L, Morhy, S, Fischer, C, Vieira, M, Afonso, T, Abreu, J, Falcao, S, Moises, V, Gouvea, A, Joao, G, Mancuso, F, Silva, C, Souza, A, Abboud, C, de Mattos Barretto, R, Ramos, A, Arnoni, R, Assef, J, Togna, D, Le Bihan, D, Miglioli, L, Oliveira, A, Kroll, R, Cortez, D, Gelape, C, De Abreu Ferrari, T, Chan, K, Hay, K, Le, V, Page, M, Poulin, F, Sauve, C, Serri, K, Mercure, C, Beaudoin, J, Pibarot, P, Sebag, I, Rudski, L, Ricafort, G, Barsic, B, Krajinovic, V, Vargovic, M, Separovic-Hanzevacki, J, Lovric, D, Reskovic-Luksic, V, Vincelj, J, Jurinjak, S, Yiannikourides, V, Ioannides, M, Kyriakou, C, Pofaides, C, Masoura, V, Yiangou, K, Pudich, J, Linhart, A, Siranec, M, Marek, J, Blechova, K, Kamenik, M, Pelouch, R, Coufal, Z, Mikulica, M, Griva, M, Jancova, E, Mikulcova, M, Taborsky, M, Precek, J, Jecmenova, M, Latal, J, Widimsky, J, Butta, T, Machacek, S, Vancata, R, Spinar, J, Holicka, M, Long, F, Anzules, N, Carpio, A, Largacha, G, Penaherrera, E, Moreira, D, Mahfouz, E, Elsafty, E, Soliman, A, Zayed, Y, Aboulenein, J, Abdel-Hay, M, Almaghraby, A, Abdelnaby, M, Ahmed, M, Hammad, B, Saleh, Y, Zahran, H, Elgebaly, O, Saad, A, Ali, M, Zeid, A, Sharkawy, R, Meshaal, M, Al Kholy, A, Doss, R, Osama, D, Rizk, H, Elmogy, A, Mishriky, M, Assayag, P, Hatimi, S, Botelho-Nevers, S, Campisi, S, Fuzellier, J, Gagneux-Brunon, A, Pierrard, R, Tulane, C, Detoc, M, Mehalla, T, Boutoille, D, Al Habash, O, Asseray-Madani, N, Biron, C, Brochard, J, Caillon, J, Cueff, C, Le Tourneau, T, Lecompte, A, Lecomte, R, Lefebvre, M, Michel, M, Pattier, S, Delarue, S, Le Bras, M, Orain, J, Faucher, J, Aboyans, V, Beeharry, A, Durox, H, Lacoste, M, Mohty, D, David, A, Pradel, V, Sierra, V, Neykova, A, Bettayeb, B, Elkentaoui, S, Tzvetkov, B, Landry, G, Strady, C, Ainine, K, Baumard, S, Brasselet, C, Tassigny, C, Valente-Pires, V, Lefranc, M, Hoen, B, Lefevre, B, Curlier, E, Callier, C, Fourcade, N, Jobic, Y, Ansard, S, Le Berre, R, Le Roux, P, Le Ven, F, Pouliquen, M, Prat, G, Bouchart, F, Savoure, A, Alarcon, C, Chapuzet, C, Gueit, I, Tribouilloy, C, Bohbot, Y, Peugnet, F, Gun, M, Duval, X, Lescure, X, Ilic-Habensus, E, Sadoul, N, Chevalier, E, Goehringer, F, Huttin, O, Garcia, R, Le Marcis, V, Tattevin, P, Donal, E, Flecher, E, Revest, M, Hubert, S, Casalta, J, Gouriet, F, Arregle, F, Cammilleri, S, Tessonnier, L, Riberi, A, Chirouze, C, Bouiller, K, Brunel, A, Fournier, D, Hustache-Mathieu, L, Klopfenstein, T, Moreau, J, Lim, P, Oliver, L, Ternacle, J, Moussafeur, A, Chavanet, P, Piroth, L, Buisson, M, Mahy, S, Martins, C, Salmon-Rousseau, A, Gohier, S, Borgermann, J, Guckel, D, Horstkotte, D, Brockmeier, B, Winkelmann, E, Hagendorff, A, Grey, D, Nickenig, G, Schueler, R, Ozturk, C, Stohr, E, Hamm, C, Walther, T, Brandt, R, Fruhauf, A, Hartung, C, Hellner, C, Wild, C, Becker, M, Hamada, S, Kaestner, W, Stangl, K, Knebel, F, Baldenhofer, G, Brecht, A, Dreger, H, Isner, C, Pfafflin, F, Stegemann, M, Zahn, R, Fraiture, B, Kilkowski, C, Karcher, A, Klinger, S, Tolksdorf, H, Tousoulis, D, Aggeli, C, Sarri, G, Sideris, S, Venieri, E, Athanassopoulos, G, Tsiapras, D, Armenis, I, Koutsiari, A, Floros, G, Grassos, C, Dragasis, S, Rallidis, L, Varlamos, C, Michalis, L, Naka, K, Bechlioulis, A, Kotsia, A, Lakkas, L, Pappas, K, Papadopoulos, C, Kiokas, S, Lioni, A, Misailidou, S, Barbetseas, J, Bonou, M, Kapelios, C, Tomprou, I, Zerva, K, Manolis, A, Hamodraka, E, Athanasiou, D, Haralambidis, G, Poulimenos, L, Samaras, H, Nagy, A, Bartykowszki, A, Gara, E, Sengupta, S, Mungulmare, K, Kasliwal, R, Bansal, M, Bhan, A, Ranjan, S, Kyavar, M, Maleki, M, Bezanjani, F, Sadeghpour, A, Alizadehasl, A, Boudagh, S, Ghavidel, A, Moradnejad, P, Pasha, H, Ghadrdoost, B, Gilon, D, Strahilevitz, J, Israel, S, Wanounou, M, D'Agostino, C, Colonna, P, De Michele, L, Fumarola, F, Stante, M, Marchionni, N, Scheggi, V, Alterini, B, Del Pace, S, Stefano, P, Sparano, C, Badano, L, Muraru, D, Ruozi, N, Tenaglia, R, Limbruno, U, Cresti, A, Baratta, P, Solari, M, Giannattasio, C, Moreo, A, De Chiara, B, Montero, B, Musca, F, Orcese, C, Panzeri, F, Russo, C, Spano, F, Alfieri, O, De Bonis, M, Agricola, E, Busnardo, E, Carletti, S, Castiglioni, B, Chiappetta, S, Del Forno, B, Ferrara, D, Guffanti, M, Iaci, G, Lapenna, E, Nisi, T, Oltolini, C, Pajoro, U, Pasciuta, R, Ripa, M, Scarpellini, P, Din, C, Meneghin, R, Schiavi, D, Piscione, F, Citro, R, Benvenga, R, Greco, L, Prota, C, Radano, I, Soriente, L, Bellino, M, Di Vece, D, Santini, F, Salsano, A, Olivieri, G, Turrini, F, Messora, R, Tondi, S, Olaru, A, Agnoletto, V, Grassi, L, Leonardi, C, Sansoni, S, Del Ponte, S, Dato, G, Ohte, N, Kikuchi, S, Wakami, K, Aonuma, K, Seo, Y, Ishizu, T, Machino-Ohtsuka, T, Yamamoto, M, Iida, N, Nakajima, H, Nakagawa, Y, Izumi, C, Amano, M, Miyake, M, Takahashi, K, Shiojima, I, Miyasaka, Y, Maeba, H, Suwa, Y, Taniguchi, N, Tsujimoto, S, Kitai, T, Ota, M, Yuda, S, Sasaki, S, Hagiwara, N, Yamazaki, K, Ashihara, K, Arai, K, Saitou, C, Saitou, S, Suzuki, G, Shibata, Y, Watanabe, N, Nishino, S, Ashikaga, K, Kuriyama, N, Mahara, K, Abe, K, Fujimaki, H, Okubo, T, Shitan, H, Takanashi, S, Terada, M, Yamamoto, H, Sata, M, Kusunose, K, Saijo, Y, Seno, H, Yuichiro, O, Sakata, Y, Mizuno, H, Nakatani, S, Onishi, T, Sengoku, K, Sera, F, Park, S, Kyoung, K, Yeon, L, Hwang, J, Jin-Oh, C, Sang-Chol, L, Sung-A, C, Jang, S, Kang, D, Heo, R, Lee, S, Song, J, Jung, E, Plisiene, J, Dambrauskaite, A, Gruodyte, G, Jonkaitiene, R, Vaskelyte, J, Mizariene, V, Atkocaityte, J, Zvirblyte, R, Sow, R, Codreanu, A, De la Vega, E, Michaux, C, Staub, T, Jacobs-Orazi, L, Azzopardi, C, Xuereb, R, Piscopo, T, Borg, D, Casha, R, Farrugia, J, Fenech, M, Pllaha, E, Vella, C, Yamagata, K, Grib, L, Raevschi, E, Grejdieru, A, Balan, G, Cardaniuc, I, Cardaniuc, L, Corcea, V, Feodorovici, A, Gaina, V, Girbu, L, Jimbei, P, Kravcenco, D, Panfile, E, Prisacari, E, Samohvalov, E, Samohvalov, S, Sceglova, N, Benesco, I, Marian, V, Sumarga, N, Mirocevic, M, Bozovic, B, Bulatovic, N, Lakovic, P, Music, L, Roos-Hesselink, J, Budde, R, Gamela, T, Wahadat, A, Kamp, O, Meijers, T, Van Melle, J, Deursen, V, Crijns, H, Bekkers, S, Cheriex, E, Gilbers, M, Kietselaer, B, Knackstedt, C, Lorusso, R, Schalla, S, Streukens, S, Chamuleau, S, Cramer, M, Teske, A, Van der Spoel, T, Wind, A, Liesbek, O, Lokhorst, J, Van Heusden, H, Tanis, W, Van der Bilt, I, Vriend, J, De Lange-van Bruggen, H, Karijodikoro, E, van Dongen, E, Schoep, J, Stolk, V, Axler, O, Baumann, F, Lebras, S, Edvardsen, T, Offstad, J, Beitnes, J, Helle-Valle, T, Skulstad, H, Skardal, R, Qamar, N, Furnaz, S, Ahmed, B, Butt, M, Khanzada, M, Saghir, T, Wahid, A, Hryniewiecki, T, Szymanski, P, Marzec, K, Misztal-Ogonowska, M, Kosmala, W, Przewlocka-Kosmala, M, Rojek, A, Woznicka, K, Zachwyc, J, Lisowska, A, Kaminska, M, Kasprzak, J, Kowalczyk, E, Strzecka, D, Wejner-Mik, P, Trabulo, M, Freitas, P, Ranchordas, S, Rodrigues, G, Pinto, P, Queiros, C, Azevedo, J, Marques, L, Seabra, D, Branco, L, Cruz, M, Galrinho, A, Moreira, R, Rio, P, Timoteo, A, Selas, M, Cardim, N, Carmelo, V, Neves, B, Pereira, H, Cruz, I, Guerra, A, Marques, A, Pintassilgo, I, Tomescu, M, Trofenciuc, N, Andor, M, Bordejevic, A, Branea, H, Caruntu, F, Cirin, L, Citu, I, Cotoraci, C, Darabantiu, D, Farcas, R, Marincu, I, Mavrea, A, Onel, M, Parvanescu, T, Pop, D, Pop-Moldovan, A, Puticiu, M, Velcean, L, Ionac, A, Cozma, D, Mornos, C, Goanta, F, Popescu, I, Beyer, R, Mada, R, Rancea, R, Rosianu, H, Tomoaia, R, Stanescu, C, Kobalava, Z, Karaulova, J, Kotova, E, Milto, A, Pisaryuk, A, Povalyaev, N, Sorokina, M, Alrahimi, J, Elshiekh, A, Jamiel, A, Ahmed, A, Al-Mallah, M, Attia, N, Putnikovic, B, Neskovic, A, Dimic, A, Ivanovic, B, Matic, S, Trifunovic, D, Petrovic, J, Kosevic, D, Dabic, P, Milojevic, P, Petrovic, I, Stojanovic, I, Kovacevic, M, Redzek, A, Stefanovic, M, Susak, S, Velicki, L, Vulin, A, Yeo, T, Poh, K, Vilacosta, I, Nasser, M, Ferrera, C, Olmos, C, Iglesias, F, Blanco-Gonzalez, E, Amaro, M, Germinas, A, Lopez-Rodriguez, E, Adan, J, Pazos-Lopez, P, Loureiro, M, Perez, M, Raposeiras-Roubin, S, Yas, S, Suarez-Varela, M, Vidal, F, Garcia-Dorado, D, Sambola, A, Fernandez-Hidalgo, N, Gonzalez-Alujas, T, Lozano, J, Maisterra, O, Pizzi, N, Rios, R, Tornos, P, Bayes-Genis, A, Botet, L, Vallejo, N, Berastegui, E, Llibre, C, Mateu, L, Nunez, R, Quesada, D, Portell, D, Vinas, J, Bertran, X, Tarradellas, R, Ricon, P, de Llano, C, Arnau, M, Bel, A, Blanes, M, Osa, A, Anguita, M, Carrasco, F, Castillo, J, Zamorano, J, Mur, J, Alvaro, M, Fernandez-Golfin, C, Monteagudo, J, Elorza, E, Alvarez, M, Balbin, J, Arminanzas, C, de las Revillas, F, Garcia, A, Belaustegui, M, Sampedro, M, Cuadra, M, Gutierrez-Diez, J, Zarauza, J, Cuello, L, Rico, C, Rodriguez-Alvarez, R, Goikoetxea, J, Montejo, M, Miro, J, Almela, M, Ambrosioni, J, Falces, C, Fuster, D, Garcia-de-la-Maria, C, Hernandez-Meneses, M, Llopis, J, Marco, F, Moreno, A, Quintana, E, Sandoval, E, Tellez, A, Tolosana, J, Vidal, B, Ruiz-Zamora, I, Ruiz, A, Girgas, E, Garcia-Pardo, G, Marzo, M, Oviedo, A, Jimenez, A, Abid, L, Hammami, R, Kammoun, S, Mourali, M, Zghal, F, Hlima, M, Boudiche, S, Ouali, S, Zakhama, L, Antit, S, Slama, I, Gulel, O, Sahin, M, Sade, L, Karacaglar, E, Kucukoglu, S, Cetinarslan, O, Yasar, U, Canpolat, U, Atas, H, Dervishova, R, Ileri, C, Zaky, H, Alhashmi, J, Baslib, F, Tahir, J, Zarger, P, Woldman, S, Menezes, L, Primus, C, Uppal, R, Bvekerwa, I, Chandrasekaran, B, Kopanska, A, Prendergast, B, Cannata, S, Chambers, J, Hancock, J, Klein, J, Rajani, R, Ursi, M, Dworakowski, R, Fife, A, Breeze, J, Browne-Morgan, M, Gunning, M, Streather, S, Asch, F, Zemedkun, M, Alyavi, B, Uzokov, J, Pazdernik M., Iung B., Mutlu B., Alla F., Riezebos R., Kong W., Nunes M. C. P., Pierard L., Srdanovic I., Yamada H., De Martino A., Miglioranza M. H., Magne J., Piper C., Laroche C., Maggioni A. P., Lancellotti P., Habib G., Selton-Suty C., Ronderos R., Avegliano G., Oses P. F., Filipini E., Granada I., Iribarren A., Mahia M., Nacinovich F., Ressi S., Obregon R., Bangher M., Dho J., Cartasegna L., Plastino M. L., Novas V., Shigel C., Reyes G., De Santos M., Gastaldello N., Fernandez M. G., Potito M., Streitenberger G., Velazco P., Casabe J. H., Cortes C., Guevara E., Salmo F., Seijo M., Weidinger F., Heger M., Brooks R., Stollberger C., Ho C. -Y., Perschy L., Puskas L., Goliasch G., Binder C., Rosenhek R., Schneider M., Winter M. -P., Hoffer E., Melissopoulou M., Lecoq E., Legrand D., Jacquet S., Massoz M., Dulgheru R., Marchetta S., DEmal C., Oury C., Cosyns B., Droogmans S., Kerkhove D., Motoc A., Plein D., Roosens B., Soens L., Weytjens C., Lemoine I., Rodrigus I., Paelinck B., Amsel B., Unger P., Konopnicki D., Beauloye C., Pasquet A., Pierard S., Vancraeynest D., Vanoverschelde J. L., Sinnaeve F., Andrade J. L., Rodrigues A. C. T., Staszko K., Dos Santos Monteiro R., Shuha D. L., Alcantara M., Cravo V., Fazzio L., Felix A., Iso M., Musa C., Siciliano A. P., Filho F. V., Braga J., Rodrigues A., Silva R., Vilela F., Rodrigues D., Silva L., Morhy S., Fischer C., Vieira M., Afonso T., Abreu J., Falcao S. N., Moises V., Gouvea A., Joao G., Mancuso F., Silva C., Souza A. C., Abboud C. S., de Mattos Barretto R. B., Ramos A., Arnoni R., Assef J. E., Togna D. J. D., Le Bihan D., Miglioli L., Oliveira A. P. R., Kroll R. T. M., Cortez D., Gelape C. L., De Abreu Ferrari T. C., Chan K. -L., Hay K., Le V., Page M., Poulin F., Sauve C., Serri K., Mercure C., Beaudoin J., Pibarot P., Sebag I., Rudski L., Ricafort G., Barsic B., Krajinovic V., Vargovic M., Separovic-Hanzevacki J., Lovric D., Reskovic-Luksic V., Vincelj J., Jurinjak S. J., Yiannikourides V., Ioannides M., Kyriakou C., Pofaides C., Masoura V., Yiangou K., Pudich J., Linhart A., Siranec M., Marek J., Blechova K., Kamenik M., Pelouch R., Coufal Z., Mikulica M., Griva M., Jancova E., Mikulcova M., Taborsky M., Precek J., Jecmenova M., Latal J., Widimsky J., Butta T., Machacek S., Vancata R., Spinar J., Holicka M., Long F. P. C., Anzules N., Carpio A. B., Largacha G., Penaherrera E., Moreira D., Mahfouz E., Elsafty E., Soliman A., Zayed Y., Aboulenein J., Abdel-Hay M., Almaghraby A., Abdelnaby M., Ahmed M., Hammad B., Saleh Y., Zahran H., Elgebaly O., Saad A., Ali M., Zeid A., Sharkawy R. E., Meshaal M., Al Kholy A., Doss R., Osama D., Rizk H., Elmogy A., Mishriky M., Assayag P., Hatimi S. E., Botelho-Nevers S. -E., Campisi S., Fuzellier J. -F., Gagneux-Brunon A., Pierrard R., Tulane C., Detoc M., Mehalla T., Boutoille D., Al Habash O., Asseray-Madani N., Biron C., Brochard J., Caillon J., Cueff C., Le Tourneau T., Lecompte A. S., Lecomte R., Lefebvre M., Michel M. M. M., Pattier S., Delarue S., Le Bras M., Orain J., Faucher J. -F., Aboyans V., Beeharry A., Durox H., Lacoste M., Mohty D., David A., Pradel V., Sierra V., Neykova A., Bettayeb B., Elkentaoui S., Tzvetkov B., Landry G., Strady C., Ainine K., Baumard S., Brasselet C., Tassigny C., Valente-Pires V., Lefranc M., Hoen B., Lefevre B., Curlier E., Callier C., Fourcade N., Jobic Y., Ansard S., Le Berre R., Le Roux P., Le Ven F., Pouliquen M. -C., Prat G., Bouchart F., Savoure A., Alarcon C., Chapuzet C., Gueit I., Tribouilloy C., Bohbot Y., Peugnet F., Gun M., Duval X., Lescure X., Ilic-Habensus E., Sadoul N., Chevalier E., Goehringer F., Huttin O., Garcia R., Le Marcis V., Tattevin P., Donal E., Flecher E., Revest M., Hubert S., Casalta J. -P., Gouriet F., Arregle F., Cammilleri S., Tessonnier L., Riberi A., Chirouze C., Bouiller K., Brunel A. -S., Fournier D., Hustache-Mathieu L., Klopfenstein T., Moreau J., Lim P., Oliver L., Ternacle J., Moussafeur A., Chavanet P., Piroth L., Buisson M., Mahy S., Martins C., Salmon-Rousseau A., Gohier S., Borgermann J., Guckel D., Horstkotte D., Brockmeier B., Winkelmann E., Hagendorff A., Grey D., Nickenig G., Schueler R., Ozturk C., Stohr E., Hamm C., Walther T., Brandt R., Fruhauf A. -C., Hartung C. T., Hellner C., Wild C., Becker M., Hamada S., Kaestner W., Stangl K., Knebel F., Baldenhofer G., Brecht A., Dreger H., Isner C., Pfafflin F., Stegemann M., Zahn R., Fraiture B., Kilkowski C., Karcher A. -K., Klinger S., Tolksdorf H., Tousoulis D., Aggeli C., Sarri G., Sideris S., Venieri E., Athanassopoulos G., Tsiapras D., Armenis I., Koutsiari A., Floros G., Grassos C., Dragasis S., Rallidis L., Varlamos C., Michalis L., Naka K., Bechlioulis A., Kotsia A., Lakkas L., Pappas K., Papadopoulos C., Kiokas S., Lioni A., Misailidou S., Barbetseas J., Bonou M., Kapelios C., Tomprou I., Zerva K., Manolis A., Hamodraka E., Athanasiou D., Haralambidis G., Poulimenos L., Samaras H., Nagy A., Bartykowszki A., Gara E., Sengupta S., Mungulmare K., Kasliwal R., Bansal M., Bhan A., Ranjan S., Kyavar M., Maleki M., Bezanjani F. N., Sadeghpour A., Alizadehasl A., Boudagh S., Ghavidel A., Moradnejad P., Pasha H. R., Ghadrdoost B., Gilon D., Strahilevitz J., Israel S., Wanounou M., d'Agostino C., Colonna P., De Michele L., Fumarola F., Stante M., Marchionni N., Scheggi V., Alterini B., Del Pace S., Stefano P., Sparano C., Badano L., Muraru D., Ruozi N., Tenaglia R., Limbruno U., Cresti A., Baratta P., Solari M., Giannattasio C., Moreo A., De Chiara B., Montero B. L., Musca F., Orcese C. A., Panzeri F., Russo C. F., Spano F., Alfieri O., De Bonis M., Agricola E., Busnardo E., Carletti S., Castiglioni B., Chiappetta S., Del Forno B., Ferrara D., Guffanti M., Iaci G., Lapenna E., Nisi T., Oltolini C., Pajoro U., Pasciuta R., Ripa M., Scarpellini P., Din C. T., Meneghin R., Schiavi D., Piscione F., Citro R., Benvenga R. M., Greco L., Prota C., Radano I., Soriente L., Bellino M., Di Vece D., Santini F., Salsano A., Olivieri G. M., Turrini F., Messora R., Tondi S., Olaru A., Agnoletto V., Grassi L., Leonardi C., Sansoni S., Del Ponte S., Dato G. M. 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Abstract

Purpose: High mortality and a limited performance of valvular surgery are typical features of infective endocarditis (IE) in octogenarians, even though surgical treatment is a major determinant of a successful outcome in IE. Methods: Data from the prospective multicentre ESC EORP EURO-ENDO registry were used to assess the prognostic role of valvular surgery depending on age. Results: As compared to < 80 yo patients, ≥ 80 yo had lower rates of theoretical indication for valvular surgery (49.1% vs. 60.3%, p < 0.001), of surgery performed (37.0% vs. 75.5%, p < 0.001), and a higher in-hospital (25.9% vs. 15.8%, p < 0.001) and 1-year mortality (41.3% vs. 22.2%, p < 0.001). By multivariable analysis, age per se was not predictive of 1-year mortality, but lack of surgical procedures when indicated was strongly predictive (HR 2.98 [2.43–3.66]). By propensity analysis, 304 ≥ 80 yo were matched to 608 < 80 yo patients. Propensity analysis confirmed the lower rate of indication for valvular surgery (51.3% vs. 57.2%, p = 0.031) and of surgery performed (35.3% vs. 68.4%, p < 0.0001) in ≥ 80 yo. Overall mortality remained higher in ≥ 80 yo (in-hospital: HR 1.50[1.06–2.13], p = 0.0210; 1-yr: HR 1.58[1.21–2.05], p = 0.0006), but was not different from that of < 80 yo among those who had surgery (in-hospital: 19.7% vs. 20.0%, p = 0.4236; 1-year: 27.3% vs. 25.5%, p = 0.7176). Conclusion: Although mortality rates are consistently higher in ≥ 80 yo patients than in < 80 yo patients in the general population, mortality of surgery in ≥ 80 yo is similar to < 80 yo after matching patients. These results confirm the importance of a better recognition of surgical indication and of an increased performance of surgery in ≥ 80 yo patients.

Published
2022

41. Comparison of the Accuracy of the 7-Item HADS Depression Subscale and 14-Item Total HADS for Screening for Major Depression: A Systematic Review and Individual Participant Data Meta-Analysis

Author

Wu, Y, Levis, B, Daray, FM, Ioannidis, JPA, Patten, SB, Cuijpers, P, Ziegelstein, RC, Gilbody, S, Fischer, FH, Fan, S, Sun, Y, He, C, Krishnan, A, Neupane, D, Bhandari, PM, Negeri, Z, Riehm, KE, Rice, DB, Azar, M, Yan, XW, Imran, M, Chiovitti, MJ, Boruff, JT, McMillan, D, Kloda, LA, Markham, S, Henry, M, Ismail, Z, Loiselle, CG, Mitchell, ND, Al-Adawi, S, Beck, KR, Beraldi, A, Bernstein, CN, Boye, B, Buel-Drabe, N, Bunevicius, A, Can, C, Carter, G, Chen, C-K, Cheung, G, Clover, K, Conroy, RM, Costa-Requena, G, Cukor, D, Dabscheck, E, De Souza, J, Downing, M, Feinstein, A, Ferentinos, PP, Flint, AJ, Gallagher, P, Gandy, M, Grassi, L, Haerter, M, Hernando, A, Jackson, ML, Jenewein, J, Jette, N, Juliao, M, Kjaergaard, M, Kohler, S, Konig, H-H, Krishna, LKR, Lee, Y, Loebner, M, Loosman, WL, Love, AW, Loewe, B, Malt, UF, Marrie, RA, Massardo, L, Matsuoka, Y, Mehnert, A, Michopoulos, I, Misery, L, Nelson, CJ, Ng, CG, O'Donnell, ML, O'Rourke, SJ, Ozturk, A, Pabst, A, Pasco, JA, Peceliuniene, J, Pintor, L, Ponsford, JL, Pulido, F, Quinn, TJ, Reme, SE, Reuter, K, Riedel-Heller, SG, Rooney, AG, Sanchez-Gonzalez, R, Saracino, RM, Schellekens, MPJ, Scherer, M, Schwarzbold, ML, Cankorur, VS, Sharpe, L, Sharpe, M, Simard, S, Singer, S, Stafford, L, Stone, J, Strobe, NA, Sultan, S, Teixeira, AL, Tiringer, I, Turner, A, Walker, J, Walterfang, M, Wang, L-J, Weyerer, SB, White, J, Wiese, B, Williams, LJ, Wong, L-Y, Benedetti, A, Thombsi, BD, Wu, Y, Levis, B, Daray, FM, Ioannidis, JPA, Patten, SB, Cuijpers, P, Ziegelstein, RC, Gilbody, S, Fischer, FH, Fan, S, Sun, Y, He, C, Krishnan, A, Neupane, D, Bhandari, PM, Negeri, Z, Riehm, KE, Rice, DB, Azar, M, Yan, XW, Imran, M, Chiovitti, MJ, Boruff, JT, McMillan, D, Kloda, LA, Markham, S, Henry, M, Ismail, Z, Loiselle, CG, Mitchell, ND, Al-Adawi, S, Beck, KR, Beraldi, A, Bernstein, CN, Boye, B, Buel-Drabe, N, Bunevicius, A, Can, C, Carter, G, Chen, C-K, Cheung, G, Clover, K, Conroy, RM, Costa-Requena, G, Cukor, D, Dabscheck, E, De Souza, J, Downing, M, Feinstein, A, Ferentinos, PP, Flint, AJ, Gallagher, P, Gandy, M, Grassi, L, Haerter, M, Hernando, A, Jackson, ML, Jenewein, J, Jette, N, Juliao, M, Kjaergaard, M, Kohler, S, Konig, H-H, Krishna, LKR, Lee, Y, Loebner, M, Loosman, WL, Love, AW, Loewe, B, Malt, UF, Marrie, RA, Massardo, L, Matsuoka, Y, Mehnert, A, Michopoulos, I, Misery, L, Nelson, CJ, Ng, CG, O'Donnell, ML, O'Rourke, SJ, Ozturk, A, Pabst, A, Pasco, JA, Peceliuniene, J, Pintor, L, Ponsford, JL, Pulido, F, Quinn, TJ, Reme, SE, Reuter, K, Riedel-Heller, SG, Rooney, AG, Sanchez-Gonzalez, R, Saracino, RM, Schellekens, MPJ, Scherer, M, Schwarzbold, ML, Cankorur, VS, Sharpe, L, Sharpe, M, Simard, S, Singer, S, Stafford, L, Stone, J, Strobe, NA, Sultan, S, Teixeira, AL, Tiringer, I, Turner, A, Walker, J, Walterfang, M, Wang, L-J, Weyerer, SB, White, J, Wiese, B, Williams, LJ, Wong, L-Y, Benedetti, A, and Thombsi, BD

Abstract

The seven-item Hospital Anxiety and Depression Scale Depression subscale (HADS-D) and the total score of the 14-item HADS (HADS-T) are both used for major depression screening. Compared to the HADS-D, the HADS-T includes anxiety items and requires more time to complete. We compared the screening accuracy of the HADS-D and HADS-T for major depression detection. We conducted an individual participant data meta-analysis and fit bivariate random effects models to assess diagnostic accuracy among participants with both HADS-D and HADS-T scores. We identified optimal cutoffs, estimated sensitivity and specificity with 95% confidence intervals, and compared screening accuracy across paired cutoffs via two-stage and individual-level models. We used a 0.05 equivalence margin to assess equivalency in sensitivity and specificity. 20,700 participants (2,285 major depression cases) from 98 studies were included. Cutoffs of ≥7 for the HADS-D (sensitivity 0.79 [0.75, 0.83], specificity 0.78 [0.75, 0.80]) and ≥15 for the HADS-T (sensitivity 0.79 [0.76, 0.82], specificity 0.81 [0.78, 0.83]) minimized the distance to the top-left corner of the receiver operating characteristic curve. Across all sets of paired cutoffs evaluated, differences of sensitivity between HADS-T and HADS-D ranged from -0.05 to 0.01 (0.00 at paired optimal cutoffs), and differences of specificity were within 0.03 for all cutoffs (0.02-0.03). The pattern was similar among outpatients, although the HADS-T was slightly (not nonequivalently) more specific among inpatients. The accuracy of HADS-T was equivalent to the HADS-D for detecting major depression. In most settings, the shorter HADS-D would be preferred. (PsycInfo Database Record (c) 2023 APA, all rights reserved).

Published
2023

42. Pasta: A Case for Hybrid Homomorphic Encryption

Author

Dobraunig, C., Grassi, L., Helminger, L., Rechberger, C., Schofnegger, M., Walch, R., Dobraunig, C., Grassi, L., Helminger, L., Rechberger, C., Schofnegger, M., and Walch, R.

Abstract

Contains fulltext : 294720.pdf (Publisher’s version ) (Open Access)

Published
2023

44. Surgery and outcome of infective endocarditis in octogenarians: prospective data from the ESC EORP EURO-ENDO registry

Author

Pazdernik, Michal, Iung, Bernard, Mutlu, Bulent, Alla, François, Riezebos, Robert, Kong, William, Nunes, Maria Carmo Pereira, Pierard, Luc, Srdanovic, Ilija, Yamada, Hirotsugu, de Martino, Andrea, Miglioranza, Marcelo Haertel, Magne, Julien, Piper, Cornelia, Laroche, C. cile, Maggioni, Aldo P., Lancellotti, Patrizio, Habib, Gilbert, Selton-Suty, Christine, Ronderos, R., Avegliano, G., Oses, P. Fernandez, Filipini, E., Granada, I., Iribarren, A., Mahia, M., Nacinovich, F., Ressi, S., Obregon, R., Bangher, M., Dho, J., Cartasegna, L., Plastino, M. L., Novas, V., Shigel, C., Reyes, G., de Santos, M., Gastaldello, N., Fernandez, M. Granillo, Potito, M., Streitenberger, G., Velazco, P., Casabé, J. H., Cortes, C., Guevara, E., Salmo, F., Seijo, M., Weidinger, F., Heger, M., Brooks, R., Stöllberger, C., Ho, C. Y., Perschy, L., Puskas, L., Goliasch, G., Binder, C., Rosenhek, R., Schneider, M., Winter, M. P., Hoffer, E., Melissopoulou, M., Lecoq, E., Legrand, D., Jacquet, S., Massoz, M., Lancellotti, P., Pierard, L., Dulgheru, R., Marchetta, S., D´Emal, C., Oury, C., Cosyns, B., Droogmans, S., Kerkhove, D., Motoc, A., Plein, D., Roosens, B., Soens, L., Weytjens, C., Lemoine, I., Rodrigus, I., Paelinck, B., Amsel, B., Unger, P., Konopnicki, D., Beauloye, C., Pasquet, A., Pierard, S., Vancraeynest, D., Vanoverschelde, J. L., Sinnaeve, F., Andrade, J. L., Rodrigues, A. C. Tude, Staszko, K., Dos Santos Monteiro, R., Miglioranza, M. H., Shuha, D. L., Alcantara, M., Cravo, V., Fazzio, L., Felix, A., Iso, M., Musa, C., Siciliano, A. P., Filho, F. Villaca, Braga, J., Rodrigues, A., Silva, R., Vilela, F., Rodrigues, D., Silva, L., Morhy, S., Fischer, C., Vieira, M., Afonso, T., Abreu, J., Falcao, S. N., Moises, V., Gouvea, A., João, G., Mancuso, F., Silva, C., Souza, A. C., Abboud, C. S., de Mattos Barretto, R. Bellio, Ramos, A., Arnoni, R., Assef, J. E., Togna, D. J. Della, le Bihan, D., Miglioli, L., Oliveira, A. P. Romero, Kroll, R. Tadeu Magro, Cortez, D., Gelape, C. L., Nunes, M. d. C. Peirira, de Abreu Ferrari, T. C., Chan, K. L., Hay, K., le, V., Page, M., Poulin, F., Sauve, C., Serri, K., Mercure, C., Beaudoin, J., Pibarot, P., Sebag, I., Rudski, L., Ricafort, G., Barsic, B., Krajinovic, V., Vargovic, M., Separovic-Hanzevacki, J., Lovric, D., Reskovic-Luksic, V., Vincelj, J., Jurinjak, S. Jaksic, Yiannikourides, V., Ioannides, M., Kyriakou, C., Pofaides, C., Masoura, V., Yiangou, K., Pudich, J., Linhart, A., Siranec, M., Marek, J., Blechova, K., Kamenik, M., Pazdernik, M., Pelouch, R., Coufal, Z., Mikulica, M., Griva, M., Jancova, E., Mikulcova, M., Taborsky, M., Precek, J., Jecmenova, M., Latal, J., Widimsky, J., Butta, T., Machacek, S., Vancata, R., Spinar, J., Holicka, M., Long, F. Pow Chon, Anzules, N., Carpio, A. Bajana, Largacha, G., Penaherrera, E., Moreira, D., Mahfouz, E., Elsafty, E., Soliman, A., Zayed, Y., Aboulenein, J., Abdel-Hay, M., Almaghraby, A., Abdelnaby, M., Ahmed, M., Hammad, B., Saleh, Y., Zahran, H., Elgebaly, O., Saad, A., Ali, M., Zeid, A., Sharkawy, R. El, Meshaal, M., Al Kholy, A., Doss, R., Osama, D., Rizk, H., Elmogy, A., Mishriky, M., Assayag, P., Hatimi, S. El, Botelho-Nevers, Saint- E., Campisi, S., Fuzellier, J. F., Gagneux-Brunon, A., Pierrard, R., Tulane, C., Detoc, M., Mehalla, T., Boutoille, D., Al Habash, O., Asseray-Madani, N., Biron, C., Brochard, J., Caillon, J., Cueff, C., le Tourneau, T., Lecompte, A. S., Lecomte, R., Lefebvre, M., Michel, M. M. Magali, Pattier, S., Delarue, S., le Bras, M., Orain, J., Faucher, J. 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M., Turrini, F., Messora, R., Tondi, S., Olaru, A., Agnoletto, V., Grassi, L., Leonardi, C., Sansoni, S., del Ponte, S., Dato, G. M. Actis, de Martino, A., Ohte, N., Kikuchi, S., Wakami, K., Aonuma, K., Seo, Y., Ishizu, T., Machino-Ohtsuka, T., Yamamoto, M., Iida, N., Nakajima, H., Nakagawa, Y., Izumi, C., Amano, M., Miyake, M., Takahashi, K., Shiojima, I., Miyasaka, Y., Maeba, H., Suwa, Y., Taniguchi, N., Tsujimoto, S., Kitai, T., Ota, M., Yuda, S., Sasaki, S., Hagiwara, N., Yamazaki, K., Ashihara, K., Arai, K., Saitou, C., Saitou, S., Suzuki, G., Shibata, Y., Watanabe, N., Nishino, S., Ashikaga, K., Kuriyama, N., Mahara, K., Abe, K., Fujimaki, H., Okubo, T., Shitan, H., Takanashi, S., Terada, M., Yamamoto, H., Sata, M., Yamada, H., Kusunose, K., Saijo, Y., Seno, H., Yuichiro, O., Sakata, Y., Mizuno, H., Nakatani, S., Onishi, T., Sengoku, K., Sera, F., Park, S. W., Kyoung, K. Eun, Yeon, L. Ga, Hwang, J. W., Jin-Oh, C., Park, S. J., Sang-Chol, L., Sung-A, C., Jang, S. Y., Kang, D. H., Heo, R., Lee, S., Song, J. M., Jung, E., Plisiene, J., Dambrauskaite, A., Gruodyte, G., Jonkaitiene, R., Vaskelyte, J., Mizariene, V., Atkocaityte, J., Zvirblyte, R., Sow, R., Codreanu, A., de la Vega, E. C. L., Michaux, C., Staub, T., Jacobs-Orazi, L., Azzopardi, C. Mallia, Xuereb, R. G., Piscopo, T., Borg, D., Casha, R., Farrugia, J., Fenech, M., Pllaha, E., Vella, C., Yamagata, K., Grib, L., Raevschi, E., Grejdieru, A., Balan, G., Cardaniuc, I., Cardaniuc, L., Corcea, V., Feodorovici, A., Gaina, V., Girbu, L., Jimbei, P., Kravcenco, D., Panfile, E., Prisacari, E., Samohvalov, E., Samohvalov, S., Sceglova, N., Benesco, I., Marian, V., Sumarga, N., Mirocevic, M., Bozovic, B., Bulatovic, N., Lakovic, P., Music, L., Roos-Hesselink, J., Budde, R., Gamela, T., Wahadat, A., Kamp, O., Meijers, T., van Melle, J. P., Deursen, V. M., Crijns, H., Bekkers, S., Cheriex, E., Gilbers, M., Kietselaer, B., Knackstedt, C., Lorusso, R., Schalla, S., Streukens, S., Chamuleau, S., Cramer, M. 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Dworakowski, R, Fife, A, Breeze, J, Browne-Morgan, M, Gunning, M, Streather, S, Asch, F, Zemedkun, M, Alyavi, B, Uzokov, J, Clinical sciences, Cardio-vascular diseases, Medical Imaging, Pazdernik M., Iung B., MUTLU B., Alla F., Riezebos R., Kong W., Pereira Nunes M. C., Pierard L., Srdanovic I., Yamada H., et al., Bordeaux population health (BPH), Université de Bordeaux (UB)-Institut de Santé Publique, d'Épidémiologie et de Développement (ISPED)-Institut National de la Santé et de la Recherche Médicale (INSERM), Cardiology Dept, CHU Limoges, INSERM 1094, University Hospital Dupuytren, 87042, Limoges, Epidémiologie des Maladies Chroniques en zone tropicale (EpiMaCT), CHU Limoges-Institut d'Epidémiologie Neurologique et de Neurologie Tropicale-Institut National de la Santé et de la Recherche Médicale (INSERM)-OmégaHealth (ΩHealth), Université de Limoges (UNILIM)-Université de Limoges (UNILIM), Microbes évolution phylogénie et infections (MEPHI), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Département de Cardiologie [Hôpital de la Timone - APHM], Assistance Publique - Hôpitaux de Marseille (APHM)- Hôpital de la Timone [CHU - APHM] (TIMONE), Mécanismes physiopathologiques et conséquences des calcifications vasculaires - UR UPJV 7517 (MP3CV), Université de Picardie Jules Verne (UPJV)-CHU Amiens-Picardie, European Infective Endocarditis Registry (Euro-Endo), Abbott Vascular, AstraZeneca, ResMed, Sanofi, Servier, Vifor Pharma, Bayer, Boehringer Ingelheim, Bristol-Myers Squibb, Pfizer, Daiichi Sankyo Europe, Eli Lilly and Company, Gedeon Richter, and Novartis Pharma

Subjects
Microbiology (medical), Prognosi, Immunology, Infective endocarditi, Life Sciences (LIFE), INTERNATIONAL COLLABORATION, PROFILE, AGE, Elderly, Propensity analysis, Yaşam Bilimleri, Health Sciences, RISK, İmmünoloji, General Immunology and Microbiology, Infective endocarditis, Prognosis, Surgery, Temel Bilimler, Life Sciences, General Medicine, INFECTIOUS DISEASES, MED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLARE, BULAŞICI HASTALIKLAR, Yaşam Bilimleri (LIFE), [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, Propensity analysi, Natural Sciences
Abstract

Purpose: High mortality and a limited performance of valvular surgery are typical features of infective endocarditis (IE) in octogenarians, even though surgical treatment is a major determinant of a successful outcome in IE. Methods: Data from the prospective multicentre ESC EORP EURO-ENDO registry were used to assess the prognostic role of valvular surgery depending on age. Results: As compared to < 80yo patients, ≥ 80yo had lower rates of theoretical indication for valvular surgery (49.1% vs. 60.3%, p < 0.001), of surgery performed (37.0% vs. 75.5%, p < 0.001), and a higher in-hospital (25.9% vs. 15.8%, p < 0.001) and 1-year mortality (41.3% vs. 22.2%, p < 0.001). By multivariable analysis, age per se was not predictive of 1-year mortality, but lack of surgical procedures when indicated was strongly predictive (HR 2.98 [2.43–3.66]). By propensity analysis, 304 ≥ 80yo were matched to 608 < 80yo patients. Propensity analysis confirmed the lower rate of indication for valvular surgery (51.3% vs. 57.2%, p = 0.031) and of surgery performed (35.3% vs. 68.4%, p < 0.0001) in ≥ 80yo. Overall mortality remained higher in ≥ 80yo (in-hospital: HR 1.50[1.06–2.13], p = 0.0210; 1-yr: HR 1.58[1.21–2.05], p = 0.0006), but was not different from that of < 80yo among those who had surgery (in-hospital: 19.7% vs. 20.0%, p = 0.4236; 1-year: 27.3% vs. 25.5%, p = 0.7176). Conclusion: Although mortality rates are consistently higher in ≥ 80yo patients than in < 80yo patients in the general population, mortality of surgery in ≥ 80yo is similar to < 80yo after matching patients. These results confirm the importance of a better recognition of surgical indication and of an increased performance of surgery in ≥ 80yo patients.

Published
2022

45. The 4πγ highly-efficient light-charged-particle detector EUCLIDES, installed at the GALILEO array for in-beam 4πγ-ray spectroscopy

Author

Testov, D., Mengoni, D., Goasduff, A., Gadea, A., Isocrate, R., John, P. R., de Angelis, G., Bazzacco, D., Boiano, C., Boso, A., Cocconi, P., Dueñas, J. A., Egea Canet, F. J., Grassi, L., Hadyńska-Klek, K., Jaworski, G., Lunardi, S., Menegazzo, R., Napoli, D. R., Recchia, F., Siciliano, M., and Valiente-Dobón, J. J.

Published
2019
Full Text
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46. Characteristics, management, and outcomes of patients with left-sided infective endocarditis complicated by heart failure:a substudy of the ESC-EORP EURO-ENDO (European infective endocarditis) registry

Author

Bohbot, Yohann, Habib, Gilbert, Laroche, Cécile, Stöhr, Elisabeth, Chirouze, Catherine, Hernandez-Meneses, Marta, Melissopoulou, Maria, Mutlu, Bülent, Scheggi, Valentina, Branco, Luísa, Olmos, Carmen, Reyes, Graciela, Pazdernik, Michal, Iung, Bernard, Sow, Rouguiatou, Mirocevic, Maja, Lancellotti, Patrizio, Tribouilloy, Christophe, P Gale, C, Beleslin, B, Budaj, A, Chioncel, O, Dagres, N, Danchin, N, Emberson, J, Erlinge, D, Glikson, M, Gray, A, Kayikcioglu, M, P Maggioni, A, K Nagy, V, Nedoshivin, A, A-S, Petronio, Roos-Hesselink, J, Wallentin, L, Zeymer, U, Habib, G, Lancellotti, P, Cosyns, B, Donal, E, Erba, P, Iung, B, A Popescu, B, Prendergast, B, Tornos, P, Andarala, M, Berle, C, Brunel-Lebecq, A, Fiorucci, E, Laroche, C, Missiamenou, V, Taylor, C, N Ali Tatar-Chentir, N, Al-Mallah, M, M Astrom Aneq, Athanassopoulos, G, P Badano, L, Benyoussef, S, E Calderon Aranda, M Cardim, N, K-L, Chan, Cruz, I, Edvardsen, T, Goliasch, G, Hagendorff, A, Hristova, K, Kamp, O, D-H, Kang, Kong, W, Matskeplishvili, S, Meshaal, M, Mirocevic, M, N Neskovic, A, Pazdernik, M, Plonska-Gosciniak, E, Raissouni, M, Ronderos, R, E Sade, L, Sadeghpour, A, Sambola, A, Sengupta, S, Separovic-Hanzevacki, J, Takeuchi, M, Tucay, E, C Tude Rodrigues, A, Varga, A, Vaskelyte, J, Yamagata, K, Yiangou, K, Zaky, H, Granada, I, Mahia, M, Ressi, S, Nacinovich, F, Iribarren, A, P Fernandez Oses, Avegliano, G, Filipini, E, Obregon, R, Bangher, M, Dho, J, Cartasegna, L, L Plastino, M, Novas, V, Shigel, C, Reyes, G, M De Santos, Gastaldello, N, M Granillo Fernandez, Potito, M, Streitenberger, G, Velazco, P, H Casabé, J, Cortes, C, Guevara, E, Salmo, F, Seijo, M, Weidinger, F, Heger, M, Brooks, R, Stöllberger, C, C-Y, Ho, Perschy, L, Puskas, L, Binder, C, Rosenhek, R, Schneider, M, M-P, Winter, Hoffer, E, Melissopoulou, M, Lecoq, E, Legrand, D, Jacquet, S, Massoz, M, Pierard, L, Marchetta, S, Dulgheru, R, D'Emal, C, Oury, C, Droogmans, S, Kerkhove, D, Plein, D, Soens, L, Weytjens, C, Motoc, A, Roosens, 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Subjects
Male, Congestive heart failure, Survival, SURGERY, IMPACT, Hospital mortality, Infective endocarditi, Sağlık Bilimleri, Cardiovascular, Clinical Medicine (MED), Endocarditis, Bacterial/complications, PROGNOSTIC-FACTORS, KALP VE KALP DAMAR SİSTEMLERİ, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, Early surgery, Klinik Tıp (MED), Prospective Studies, Registries, PREDICTORS, ComputingMilieux_MISCELLANEOUS, Outcome, RISK, [SDV.MHEP.ME]Life Sciences [q-bio]/Human health and pathology/Emerging diseases, Klinik Tıp, DEATH, Middle Aged, Tıp, Heart Failure/complications, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology, Medicine, Female, EURO-ENDO, Cardiology and Cardiovascular Medicine, Kardiyoloji, Kardiyoloji ve Kardiyovasküler Tıp, NATIVE VALVE ENDOCARDITIS, [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, Endocarditis/complications, Health Sciences, Humans, [SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/Parasitology, Retrospective Studies, Internal Medicine Sciences, MORTALITY, MED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLARE, Dahili Tıp Bilimleri, ADULTS, Infective endocarditis, CLINICAL MEDICINE, [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology, CARDIAC & CARDIOVASCULAR SYSTEMS
Abstract

International audience; AIMS: To evaluate the current management and survival of patients with left-sided infective endocarditis (IE) complicated by congestive heart failure (CHF) in the ESC-EORP European Endocarditis (EURO-ENDO) registry. METHODS AND RESULTS: Among the 3116 patients enrolled in this prospective registry, 2449 (mean age: 60 years, 69% male) with left-sided (native or prosthetic) IE were included in this study. Patients with CHF (n~=~698, 28.5%) were older, with more comorbidity and more severe valvular damage (mitro-aortic involvement, vegetations >10\,mm and severe regurgitation/new prosthesis dehiscence) than those without CHF (all p\,≤q\,0.019). Patients with CHF experienced higher 30-day and 1-year mortality than those without (20.5% vs. 9.0% and 36.1% vs. 19.3%, respectively) and CHF remained strongly associated with 30-day (odds ratio[OR] 2.37, 95% confidence interval [CI] [1.73-3.24; p\,10\,mm, severe valvular regurgitation and/or new prosthetic dehiscence, perivalvular complication, and prosthetic IE (OR 0.22, 95% CI 0.12-0.38; p\

Published
2022

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