Search

Your search keyword '"Grant, J. W. A."' showing total 228 results
Start Over Author "Grant, J. W. A."
228 results on '"Grant, J. W. A."'

34. Multiscale modeling of mechanotransduction in the utricle.

Author

Jong-Hoon Nam, Grant, J. W., Rowe, M. H., and Peterson, E. H.

Subjects
*MULTISCALE modeling, *TURTLES, *HAIR, *MICROMECHANICS, *HAIR cells
Abstract

We review recent progress in using numerical models to relate utricular hair bundle and otoconial membrane (OM) structure to the functional requirements imposed by natural behavior in turtles. The HEAD MOVEMENTS section reviews the evolution of experimental attempts to understand vestibular system function with emphasis on turtles, including data showing that accelerations occurring during natural head movements achieve higher magnitudes and frequencies than previously assumed. The STRUCTURE section reviews quantitative anatomical data documenting topographical variation in the structures underlying macromechanical and micromechanical responses of the turtle utricle to head movement: hair bundles, OM, and bundle-OM coupling. The MACROMECHANICS section reviews macromechanical models that incorporate realistic anatomical and mechanical parameters and reveal that the system is significantly underdamped, contrary to previous assumptions. The MICROMECHANICS: HAIR BUNDLE MOTION AND MET CURRENTS section reviews work based on micromechanical models, which demonstrates that topographical variation in the structure of hair bundles and OM, and their mode of coupling, result in regional specializations for signaling of low frequency (or static) head position and high frequency head accelerations. We conclude that computational models based on empirical data are especially promising for investigating mechanotransduction in this challenging sensorimotor system. [ABSTRACT FROM AUTHOR]

Published
2019
Full Text
View/download PDF

40. Management of neck lumps--a triage model

Author

Smith, O. D., Ellis, P. D., Bearcroft, P. W., Berman, L. H., Grant, J. W., and Jani, P.

Subjects
Adult, Aged, 80 and over, Male, Adolescent, Biopsy, Needle, Middle Aged, Parotid Neoplasms, Thyroglossal Cyst, England, Head and Neck Neoplasms, Child, Preschool, Hematologic Neoplasms, Lymphatic Metastasis, Ambulatory Care, Humans, Female, Triage, Child, Research Article, Aged
Abstract

We report our experience in the out-patient triage of 100 patients presenting with a lump in the neck. The out-patient visit consisted of a general history and examination, assessment of the upper air and food passages and, where indicated, ultrasound and core needle biopsy of the lump. Other investigations were performed as appropriate. One hundred neck lump patients were seen in a 9 month period. Ninety-six of these lumps were diagnosed on an out-patient basis, only four requiring admission for formal excision biopsy. Among the diagnoses were eleven lymphomas, nine parotid neoplasms, nine lymph node metastases, five thyroglossal cysts, and four branchial cysts. Almost half the patients seen had either a reactive lymphadenopathy, or no abnormality. The establishment of a tissue diagnosis on an out-patient basis allowed appropriate referrals to be made and management plans to be formulated. The theoretical risk of seeding of malignant cells in the needle tract is acknowledged and discussed.

Published
2000

46. Mechanical properties for durability predictions of FRP bonded joint

Author

Brinson, H. F and Grant, J. W

Subjects
Structural Mechanics
Abstract

A discussion of current standard durability prediction methodology for bonded joints is given. The influence of time-dependent adhesive properties on lap shear stress distributions and interfacial stresses is presented. It is suggested that these effects may be important in durability considerations. Test geometries from which better durability information can be obtained are outlined and a general mechanics approach for durability prediction is suggested.

Published
1986
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results