117 results on '"Graf, Laszlo"'
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2. Trypsin Complexed with α1-Proteinase Inhibitor Has an Increased Structural Flexibility
3. The Catalytic Aspartate Is Protonated in the Michaelis Complex Formed between Trypsin and an in Vitro Evolved Substrate-like Inhibitor: A REFINED MECHANISM OF SERINE PROTEASE ACTION
4. Isolation, biochemical characterization, and molecular modeling of American lobster digestive cathepsin D1
5. Metastasis blood test by flow cytometry: In vivo cancer spheroids and the role of hypoxia
6. Scallop Striated and Smooth Muscle Myosin Heavy-Chain Isoforms are Produced by Alternative RNA Splicing from a Single Gene
7. Action of Cathepsin D on Human $\beta $-lipotropin: A Possible Source of Human ``$\beta $-melanotropin''
8. Electrostatic Complementarity within the Substrate-Binding Pocket of Trypsin
9. Human Pituitary Growth Hormone: Isolation and Properties of Two Biologically Active Fragments from Plasmin Digests
10. Human Somatotropin: Covalent Reconstitution of Two Polypeptide Contiguous Fragments with Thrombin
11. β -endorphin: Demonstration of a Tertiary Structure in Aqueous Solution
12. Revisiting the mechanism of the autoactivation of the complement protease C1r in the C1 complex: Structure of the active catalytic region of C1r
13. When the Surface Tells What Lies Beneath: Combinatorial Phage-display Mutagenesis Reveals Complex Networks of Surface–Core Interactions in the Pacifastin Protease Inhibitor Family
14. Enzyme:substrate hydrogen bond shortening during the acylation phase of seine protease catalysis
15. Thermodynamic Analysis Reveals Structural Rearrangement during the Acylation Step in Human Trypsin 4 on 4-Methylumbelliferyl 4-Guanidinobenzoate Substrate Analogue
16. Cloning and expression of ostrich trypsinogen: an avian trypsin with a highly sensitive autolysis site
17. Extended Intermolecular Interactions in a Serine Protease–Canonical Inhibitor Complex Account for Strong and Highly Specific Inhibition
18. Effects of serpin binding on the target proteinase: global stabilization, localized increased structural flexibility, and conserved hydrogen binding at the active site
19. Tudomány, kaland, Amerika. Egy biokémikus útkeresése II. A következő tíz év
20. Mutant rat trypsin selectively cleaves tyrosyl peptide bonds
21. Three Dimensional Structures of S189D Chymotrypsin and D189S Trypsin Mutants: The Effect of Polarity at Site 189 on a Protease-specific Stabilization of the Substrate-binding Site
22. Characterization of a trypsin-like serine protease of activated B cells mediating the cleavage of surface proteins
23. Trypsin: is there anything new under the Sun?
24. Remarkable Phylum Selectivity of a Schistocerca gregaria Trypsin Inhibitor: The Possible Role of Enzyme–Inhibitor Flexibility
25. Crystal structure reveals basis for the inhibitor resistance of human brain trypsin
26. [29] Modulation of enzyme specificity by site-directed mutagenesis
27. Specificity Assay of Serine Proteinases by Reverse-Phase High-Performance Liquid Chromatography Analysis of Competing Oligopeptide Substrate Library
28. Comparative in Vitro Studies on Native and Recombinant Human Cationic Trypsins: CATHEPSIN B IS A POSSIBLE PATHOLOGICAL ACTIVATOR OF TRYPSINOGEN IN PANCREATITIS
29. Analysis of inflammatory signatures of cancer spheroids in blood and their role in metastasis.
30. Trypsinogen Stabilization by Mutation Arg117→His: A Unifying Pathomechanism for Hereditary Pancreatitis?
31. Properties of the His57–Asp102Dyad of Rat Trypsin D189S in the Zymogen, Activated Enzyme, and α1-Proteinase Inhibitor Complexed Forms
32. Proteinase inhibitors from desert locust, Schistocerca gregaria: engineering of both P 1 and P 1′ residues converts a potent chymotrypsin inhibitor to a potent trypsin inhibitor
33. Proteolytic processing in the biosynthesis and metabolism of endorphins
34. Secondary Structure — Function Relationships in β-Endorphin : A Proposed Model of the Biologically Active Conformation
35. β-Lipotropin
36. Mechanism of lysophosphatidic acid-induced amyloid fibril formation of [[beta].sub.2]-microglobulin in vitro under physiological conditions
37. Probing conformational plasticity of the activation domain of trypsin: the role of glycine hinges
38. Abstract B03: Blood test of metastatic predisposition in colon cancer
39. Comparison of proteolytic activities produced by entomopathogenic photorhabdus bacteria: strain- and -phase-dependent heterogeneity in composition and activity of four enzymes
40. Same fold with different mobility: backbone dynamics of small protease inhibitors from the desert locust, Schistocerca gregaria
41. Chapter 582 - Chymotrypsin
42. Abstract 1545: Metastasis blood test byin vivotumorsphere detection
43. The Role of Structural Flexibility and Stability in the Interaction of Serine Proteases with their Inhibitors
44. Metastasis blood test by flow cytometry:In vivocancer spheroids and the role of hypoxia
45. Protein Flexibility Partitions the Effects of Energy Landscape Roughness Between Activation Energy and Internal Friction
46. The Relative Significance of External and Internal Friction in Protein Conformational Changes
47. Methionine-Independent Translation Initiation from Naturally Occurring Non-AUG Codons
48. Local binding with globally distributed changes in a small protease inhibitor upon enzyme binding
49. Myelin basic protein, an autoantigen in multiple sclerosis, is selectively processed by human trypsin 4
50. Disulfide-linked propeptides stabilize the structure of zymogen and mature pancreatic serine proteases
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