7 results on '"Grace MM"'
Search Results
2. P59 Lifelab southampton: improving science literacy as a tool for increasing health literacy in teenagers – a pilot cluster-randomised controlled trial
- Author
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Woods-Townsend, KS, primary, Aiston, H, additional, Bagust, L, additional, Davey, H, additional, Lovelock, D, additional, Christodoulou, A, additional, Griffiths, JB, additional, Grace, MM, additional, Godfrey, KM, additional, Hanson, MA, additional, and Inskip, HM, additional
- Published
- 2017
- Full Text
- View/download PDF
3. P59 Lifelab southampton: improving science literacy as a tool for increasing health literacy in teenagers – a pilot cluster-randomised controlled trial
- Author
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Woods-Townsend, KS, Aiston, H, Bagust, L, Davey, H, Lovelock, D, Christodoulou, A, Griffiths, JB, Grace, MM, Godfrey, KM, Hanson, MA, and Inskip, HM
- Abstract
BackgroundBehavioural risk factors are the largest contributor to the non-communicable disease burden, and those of parents can affect prenatal and infant development with lasting impact on children’s long-term health. Adolescence offers a window of opportunity during which improvements in health behaviours would not only benefit long-term health of individuals, but also enable them to be better prepared for parenthood and pass better health prospects to their children. We have developed an educational intervention, LifeLab, based around a purpose-built laboratory in University Hospital Southampton with support from teachers, to engage adolescents in understanding effects of their health behaviours for themselves and their future children.AimsTo assess whether engaging adolescents with the science behind health messages, thus improving their science literacy, increases their health literacy and hence their health behaviours.MethodsIn a pilot study, in preparation for a large cluster randomised trial of LifeLab, we recruited six schools. Three were randomised to the LifeLab intervention and three to control, with 392 students completing online questionnaires at baseline and 12 months follow up. Summary statistics were used to examine differences between groups. The categorical outcome variables were dichotomised and Poisson regression with robust variance used to obtain prevalence rate ratios (PRRs) for the outcome in relation to the intervention, adjusted for baseline values, sex and Index of Deprivation Affecting Children (IDACI) score.Results12 months post intervention, intervention students had greater understanding than control students of the influences of health behaviours on their long term health and that of their children. Compared with control students those in the intervention were more likely to agree that nutrition starts to affect our future health early in life (PRR 1.87 (95%CI 1.42–2.45) and that the food a father eats before having a baby could affect the health of his children (PRR 4.05 (95%CI: 2.34–7.01)), but no more likely to agree that it was important to eat healthy food now (PRR 1.19 95% CI: 0.79–1.79)). The students in the intervention groups took similar amounts of exercise and their diets were comparable to those in the control group.DiscussionIt is possible to change students’ scientific awareness and health literacy as measured 12 months after the LifeLab intervention, but this does not necessarily translate into behaviour change. Interventions require more than knowledge acquisition in order to motivate and sustain behaviour change.
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- 2017
- Full Text
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4. Gender, Relationship Concerns, and Intimate Partner Violence in Young Adulthood.
- Author
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Giordano PC, Grace MM, Manning WD, and Longmore MA
- Abstract
Purpose: Few studies have examined gender-specific concerns within intimate relationships that may be associated with conflict escalation and intimate partner violence (IPV). While prior theorizing has emphasized issues such as men's feelings of jealousy, the role of concerns and conflict related to men's actions has not been as thoroughly investigated. We draw on the life course perspective as background for assessing conflict areas related to men's and women's actions during the young adult period, and subsequently the association between such concerns and the odds of reporting IPV in a current/most recent relationship., Method: Building on a longitudinal data set focused on a large, diverse sample (Toledo Adolescent Relationships Study, n = 904), we administered surveys that assessed whether disagreements about potential conflict areas-including but not limited to infidelity-related to male or female partner's actions., Results: Concerns about women's and men's actions were both related to the odds of reporting IPV experience, but disagreements about male partners' actions during young adulthood were actually more common, and relative to concerns about women's actions, more strongly associated with IPV., Conclusions: Research and programmatic efforts should give additional attention to specific areas around which couples' disagreements develop and conflicts sometimes escalate. A dyadic approach adds to the frequent emphasis on emotion management and control that center primarily on one partner's problematic relationship style-thus addressing the 'form' but not the 'content' of intimate partner conflicts. This approach would highlight a broader range of relationship dynamics than are currently included in theorizing and applied efforts., Competing Interests: Conflict of Interest: The authors declare that they have no conflict of interest.
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- 2023
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5. "Micro-cultures" of conflict: Couple-level perspectives on reasons for and causes of intimate partner violence in young adulthood.
- Author
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Giordano PC, Grace MM, Longmore MA, and Manning WD
- Abstract
Objective: To highlight the development of young adult couples' shared understandings about reasons for conflict in their relationships, views about why some disagreements included the use of aggression ("causes"), and gendered perspectives on these relationship dynamics., Background: Feminist theories have centered on relationship dynamics associated with intimate partner violence (IPV), but have focused primarily on men's concerns (e.g., jealousy) and use of violence as a means of control over female partners. The current analysis drew on symbolic interaction theory as a framework for exploring couple-level concerns, and ways in which dyadic communication contributes to these understandings, or what can be considered "micro-cultures" of conflict., Method: The study relied on in-depth interviews with a heterogeneous sample of IPV-experienced young adults who had participated in a larger longitudinal study (Toledo Adolescent Relationships Study [TARS]) and separate interviews with their partners ( n = 90)., Results: Analyses revealed that women's concerns about men's actions (e.g., infidelity) were frequently cited as reasons for serious conflicts, and showed significant concordance in partners' reports. Shared understandings sometimes extended to views on the role of more distal causes (e.g., family background) and the meaning(s) of each partner's use of aggression. Gendered dynamics included men's tendency to minimize women's concerns, and both partners' more open discussions of women's perpetration., Conclusions: Theories of IPV and associated programmatic efforts should include attention to the social construction of these "micro-cultures," as these shared meanings affect behavior, are potentially malleable, and add to the more intuitive focus on one-sided forces of control and constraint., (© 2022 The Authors. Journal of Marriage and Family published by Wiley Periodicals LLC on behalf of National Council on Family Relations.)
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- 2022
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6. Synovial Chondromatosis: An Unusual Case of Knee Pain and Swelling.
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Grace MM and Letonoff EJ
- Abstract
Although it is an uncommon cause of knee pain and swelling, synovial chondromatosis should be included in the differential diagnosis when evaluating adults aged 30 years to 50 years with knee pain of insidious onset., Competing Interests: Author disclosures The authors report no actual or potential conflicts of interest with regard to this article.
- Published
- 2018
7. A physical and regulatory map of host-influenza interactions reveals pathways in H1N1 infection.
- Author
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Shapira SD, Gat-Viks I, Shum BO, Dricot A, de Grace MM, Wu L, Gupta PB, Hao T, Silver SJ, Root DE, Hill DE, Regev A, and Hacohen N
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- Apoptosis, Epithelial Cells virology, Gene Expression Profiling, Humans, Influenza A Virus, H1N1 Subtype immunology, Influenza A Virus, H1N1 Subtype pathogenicity, Interferons metabolism, Lung cytology, Lung virology, Proteomics, RNA, Small Interfering metabolism, RNA, Viral metabolism, Two-Hybrid System Techniques, Viral Nonstructural Proteins metabolism, Wnt Proteins metabolism, Host-Pathogen Interactions, Influenza A Virus, H1N1 Subtype metabolism, Viral Proteins metabolism
- Abstract
During the course of a viral infection, viral proteins interact with an array of host proteins and pathways. Here, we present a systematic strategy to elucidate the dynamic interactions between H1N1 influenza and its human host. A combination of yeast two-hybrid analysis and genome-wide expression profiling implicated hundreds of human factors in mediating viral-host interactions. These factors were then examined functionally through depletion analyses in primary lung cells. The resulting data point to potential roles for some unanticipated host and viral proteins in viral infection and the host response, including a network of RNA-binding proteins, components of WNT signaling, and viral polymerase subunits. This multilayered approach provides a comprehensive and unbiased physical and regulatory model of influenza-host interactions and demonstrates a general strategy for uncovering complex host-pathogen relationships., (Copyright 2009 Elsevier Inc. All rights reserved.)
- Published
- 2009
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