Search

Your search keyword '"Gow, Kenneth W."' showing total 556 results
Start Over Author "Gow, Kenneth W."
556 results on '"Gow, Kenneth W."'

14. Kidney Preservation and Wilms Tumor Development in Children with Diffuse Hyperplastic Perilobar Nephroblastomatosis: A Report from the Children’s Oncology Group Study AREN0534

Author

Ehrlich, Peter F., Tornwall, Brett, Chintagumpala, Murali M., Chi, Yueh-Yun, Hoffer, Fredric A., Perlman, Elizabeth J., Kalapurakal, John A., Warwick, Anne, Shamberger, Robert C., Khanna, Geetika, Hamilton, Thomas E., Gow, Kenneth W., Paulino, Arnold C., Gratias, Eric J., Mullen, Elizabeth A., Geller, James I., Fernandez, Conrad V., and Dome, Jeffrey S.

Published
2022
Full Text
View/download PDF

18. Race and Ethnic Group Enrollment and Outcomes for Wilms Tumor: Analysis of the Current Era Children’s Oncology Group Study, AREN03B2

Author

Lovvorn, Harold N, primary, Renfro, Lindsay A, additional, Benedetti, Daniel J, additional, Kotagal, Meera, additional, Phelps, Hannah M, additional, Ehrlich, Peter F, additional, Lo, Andrea C, additional, Sandberg, Jesse K, additional, Treece, Amanda L, additional, Gow, Kenneth W, additional, Glick, Richard D, additional, Davidoff, Andrew M, additional, Cost, Nicholas G, additional, Dix, David B, additional, Fernandez, Conrad V, additional, Dome, Jeffrey S, additional, Geller, James I, additional, and Mullen, Elizabeth A, additional

Published
2024
Full Text
View/download PDF

23. ASO Video Abstract: Kidney Preservation and Wilms Tumor Development in Children with Diffuse Hyperplastic Perilobar Nephroblastomatosis—A Report from the Children’s Oncology Group Study AREN0534

Author

Ehrlich, Peter F., Tornwall, Brett, Chintagumpala, Murali M., Chi, Yueh-Yun, Hoffer, Fredric A., Perlman, Elizabeth J., Kalapurakal, John A., Warwick, Anne, Shamberger, Robert C., Khanna, Geetika, Hamilton, Thomas E., Gow, Kenneth W., Paulino, Arnold C., Gratias, Eric J., Mullen, Elizabeth A., Geller, James I., Fernandez, Conrad V., and Dome, Jeffrey S.

Published
2022
Full Text
View/download PDF

24. Treatment and outcomes of clear cell sarcoma of the kidney: A report from the Children's Oncology Group studies AREN0321 and AREN03B2.

Author

Benedetti, Daniel J., Renfro, Lindsay A., Tfirn, Ian, Daw, Najat C., Kalapurakal, John A., Ehrlich, Peter F., Khanna, Geetika, Perlman, Elizabeth, Warwick, Anne, Gow, Kenneth W., Paulino, Arnold C., Seibel, Nita L., Grundy, Paul, Fernandez, Conrad V., Geller, James I., Mullen, Elizabeth A., and Dome, Jeffrey S.

Subjects
SARCOMA, CENTRAL nervous system, NEPHROBLASTOMA, KIDNEYS, DISEASE progression
Abstract

Background: On the fifth National Wilms Tumor Study, treatment for clear cell sarcoma of the kidney (CCSK) included combined vincristine, doxorubicin, cyclophosphamide, and etoposide (regimen I) plus radiation therapy (RT), yielding 5‐year event‐free survival (EFS) rates of 100%, 88%, 73%, and 29% for patients who had with stage I, II, III, and IV disease, respectively. In the Children's Oncology Group study AREN0321 of risk‐adapted therapy, RT was omitted for stage I disease if lymph nodes were sampled, and carboplatin was added for stage IV disease (regimen UH‐1). Patients who had stage II/III disease received regimen I with RT. Methods: Four‐year EFS was analyzed for patients enrolled on AREN0321 and on those enrolled on AREN03B2 who received AREN0321 stage‐appropriate chemotherapy. Results: Eighty‐two patients with CCSK enrolled on AREN0321, 50 enrolled on AREN03B2 only. The 4‐year EFS rate was 82.7% (95% confidence interval [CI], 74.8%–91.4%) for AREN0321 and 89.6% (95% CI, 81.3%–98.7%) for AREN03B2 only (p =.28). When combining studies, the 4‐year EFS rates for patients who had stage I (n = 10), II (n = 47), III (n = 65), and IV (n = 10) disease were 90% (95% CI, 73.2%–100.0%), 93.4% (95% CI, 86.4%–100.0%), 82.8% (95% CI, 74.1%–92.6%), and 58.3% (95% CI, 34%–100.0%), respectively. There were no local recurrences among seven patients with stage I disease who were treated without RT. One stage I recurrence occurred in the brain, which was the most common site of relapse overall. Among patients with local stage III tumors, neither initial procedure type, margin status, nor lymph node involvement were prognostic. Conclusions: Patients with stage I CCSK had excellent outcomes without local recurrences when treated without RT. Patients with stage IV disease appeared to benefit from a carboplatin‐containing regimen, although their outcomes remained unsatisfactory. Further research is needed to improve outcomes for patients with advanced‐stage disease (ClinicalTrials.gov identifiers NCT00335556 and NCT00898365). The results of this study indicate that treatment of clear cell sarcoma of the kidney can be risk‐adapted based on disease stage, radiotherapy should be omitted for patients with stage I disease if lymph nodes are sampled, and patients with stage IV disease appear to benefit from a carboplatin‐containing regimen. With treatment according to the Children's Oncology Group AREN0321 study, most relapses occurred within 3 years, and the most common sites of recurrence were in the central nervous system. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

27. Testicular tumors in prepubescent patients

Author

Maizlin, Ilan I., Dellinger, Matthew, Gow, Kenneth W., Goldin, Adam B., Goldfarb, Melanie, Nuchtern, Jed G., Langer, Monica, Vasudevan, Sanjeev A., Doski, John J., Raval, Mehul V., and Beierle, Elizabeth A.

Published
2018
Full Text
View/download PDF

29. The ACGME case log: General surgery resident experience in pediatric surgery

Author

Gow, Kenneth W, Drake, F Thurston, Aarabi, Shahram, and Waldhausen, John H

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Pediatric, Clinical Research, Digestive Diseases, Accreditation, Branchial Region, Clinical Competence, Cohort Studies, Diagnosis-Related Groups, Education, Medical, Graduate, Gastroesophageal Reflux, General Surgery, Herniorrhaphy, Humans, Internship and Residency, Intestinal Diseases, Laparoscopy, Orchiopexy, Pediatrics, Pyloric Stenosis, Retrospective Studies, Thoracic Surgery, Thyroglossal Cyst, Workload, General surgery, Resident, Education, Pediatric surgery, Case log, Paediatrics and Reproductive Medicine, Clinical sciences, Paediatrics
Abstract

BackgroundGeneral surgery (GS) residents in ACGME programs log cases performed during their residency. We reviewed designated pediatric surgery (PS) cases to assess for changes in performed cases over time.MethodsThe ACGME case logs for graduating GS residents were reviewed from academic year (AY) 1989-1990 to 2010-2011 for designated pediatric cases. Overall and designated PS cases were analyzed. Data were combined into five blocks: Period I (AY1989-90 to AY1993-94), Period II (AY1994-95 to AY1998-99), Period III (AY1999-00 to AY2002-03), Period IV (AY2003-04 to AY2006-07), and Period V (AY2007-08 to AY2010-11). Periods IV and V were delineated by implementation of duty hour restrictions. Student t-tests compared averages among the time periods with significance at P < .05.ResultsOverall GS case load remained relatively stable. Of total cases, PS cases accounted for 5.4% in Period I and 3.7% in Period V. Designated pediatric cases declined for each period from an average of 47.7 in Period I to 33.8 in Period V. These changes are due to a decline in hernia repairs, which account for half of cases. All other cases contributed only minimally to the pediatric cases. The only laparoscopic cases in the database were anti-reflux procedures, which increased over time.ConclusionsGS residents perform a diminishing number of designated PS cases. This decline occurred before the onset of work-hour restrictions. These changes have implications on the capabilities of the current graduating workforce. However, the case log does not reflect all cases trainees may be exposed to, so revision of this list is recommended.

Published
2013

30. ACGME case logs: Surgery resident experience in operative trauma for two decades.

Author

Drake, Frederick Thurston, Van Eaton, Erik G, Huntington, Ciara R, Jurkovich, Gregory J, Aarabi, Shahram, and Gow, Kenneth W

Subjects
Humans, Wounds and Injuries, Traumatology, Internship and Residency, Educational Measurement, United States, General Surgery, Digestive Diseases, Clinical Research, Surgical residents, trauma, ACGME, resident work-hour restrictions, education, Cardiorespiratory Medicine and Haematology, Clinical Sciences, Nursing, Emergency & Critical Care Medicine
Abstract

BackgroundSurgery resident education is based on experiential training, which is influenced by changes in clinical management strategies, technical and technologic advances, and administrative regulations. Trauma care has been exposed to each of these factors, prompting concerns about resident experience in operative trauma. The current study analyzed the reported volume of operative trauma for the last two decades; to our knowledge, this is the first evaluation of nationwide trends during such an extended time line.MethodsThe Accreditation Council for Graduate Medical Education (ACGME) database of operative logs was queried from academic year (AY) 1989-1990 to 2009-2010 to identify shifts in trauma operative experience. Annual case log data for each cohort of graduating surgery residents were combined into approximately 5-year blocks, designated Period I (AY1989-1990 to AY1993-1994), Period II (AY1994-1995 to AY1998-1999), Period III (AY1999-2000 to AY2002-2003), and Period IV (AY2003-2004 to AY2009-2010). The latter two periods were delineated by the year in which duty hour restrictions were implemented.ResultsOverall general surgery caseload increased from Period I to Period II (p < 0.001), remained stable from Period II to Period III, and decreased from Period III to Period IV (p < 0.001). However, for ACGME-designated trauma cases, there were significant declines from Period I to Period II (75.5 vs. 54.5 cases, p < 0.001) and Period II to Period III (54.5 vs. 39.3 cases, p < 0.001) but no difference between Period III and Period IV (39.3 vs. 39.4 cases). Graduating residents in Period I performed, on average, 31 intra-abdominal trauma operations, including approximately five spleen and four liver operations. Residents in Period IV performed 17 intra-abdominal trauma operations, including three spleen and approximately two liver operations.ConclusionRecent general surgery trainees perform fewer trauma operations than previous trainees. The majority of this decline occurred before implementation of work-hour restrictions. Although these changes reflect concurrent changes in management of trauma, surgical educators must meet the challenge of training residents in procedures less frequently performed.Level of evidenceEpidemiologic study, level III; therapeutic study, level IV.

Published
2012

46. Care of the Oncology Patient in the PICU

Author

Greiner, Robert J., Peterson-Carmichael, Stacey, Rothman, Jennifer A., Gow, Kenneth W., Tamburro, Robert F., Jr., Barfield, Raymond, Wheeler, Derek S., editor, Wong, Hector R., editor, and Shanley, Thomas P., editor

Published
2014
Full Text
View/download PDF

47. Hematology and Oncology in Critical Illness

Author

Brandão, Leonardo R., Howard, Scott C., Gow, Kenneth W., Rajasekaran, Surender, Tamburro, Robert F., Lucking, Steven E., editor, Maffei, Frank A., editor, Tamburro, Robert F., editor, and Thomas, Neal J., editor

Published
2012
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results