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9 results on '"Govindavarjhulla A"'

1. Triple Antiplatelet Therapy and Combinations with Oral Anticoagulants After Stent Implantation

Author

Kunadian, Vijay, Dunford, Joseph Robert, Swarbrick, Daniel, Halaby, Rim, Ajari, Ogheneochuko, Cochet, Madeleine, Feeney, Kristin, Larkin, Emily, Gonzalez, Gonzalo Romero, Govindavarjhulla, Aditya, Nethala, Daniel, Patel, Hardik, Guddeti, Raviteja Reddy, Khan, Farman, Kumar, Shankar, Patel, Sapan, Saddala, Prashanth, Serla, Vishnu Vardhan, Zacarkim, Marcelo, Yadav, Divya, and Gibson, C. Michael

Published
2013
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3. Risk Factors for the Isolation of Vancomycin-Resistant Enterococcus Faecalis from Wound Site: A Case-Case Control Analysis

Author

Palla, Mohan, Hayakawa, Kayoko, Marchaim, Dror, Mahesh, Uma, Pulluru, Harish, Lee, Kyeong Pyo, Kamatam, Srinivasa, Singla, Manit, Ajamoughli, Mayan, Bathina, Pradeep, Alshabani, Khaled, Govindavarjhulla, Aditya, Mallad, Ashwini, Ho, Kevin, Abbadi, Deepika Reddy, Chowdary, Deepti, Kakarlapudi, Hari, Guddati, Harish, Das, Manoj, Kannekanti, Naveen, Ramasamy, Balaji, Khan, Amber, Vemuri, Praveen, Doddamani, Rajiv, Mundra, Venkat Ram Rakesh, Guddeti, Raviteja Reddy, Policherla, Rohan, Bai, Sarika, Lohithaswa, Sharan, Shashidharan, Shiva Prasad, Chidurala, Sowmya, Diviti, Sreelatha, Patel, Dipenkumar, Vadlamudi, Gayathri, Obeid, Tarek, Pogue, Jason, Lephart, Paul R., Martin, Emily Toth, Rybak, Michael J., Flanagan, Elaine, and Kaye, Keith

Published
2012
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4. Risk Factors for Vancomycin-resistant Enterococcus faecalis bacteremia: A Case-Case-Control Study

Author

Hayakawa, Kayoko, Marchaim, Dror, Palla, Mohan B., Mahesh, Uma, Pulluru, Harish, Lee, Kyeong Pyo, Kamatam, Srinivasa, Singla, Manit, Ajamoughli, Mayan, Bathina, Pradeep, Alshabani, Khaled, Govindavarjhulla, Aditya, Mallad, Ashwini, Ho, Kevin, Abbadi, Deepika Reddy, Chowdary, Deepti, Kakarlapudi, Hari, Guddati, Harish, Das, Manoj, Kannekanti, Naveen, Ramasamy, Balaji, Khan, Amber, Vemuri, Praveen, Doddamani, Rajiv, Rakesh Mundra, Venkat Ram, Guddeti, Raviteja Reddy, Policherla, Rohan, Bai, Sarika, Lohithaswa, Sharan, Shashidharan, Shiva Prasad, Chidurala, Sowmya, Diviti, Sreelatha, Patel, Dipenkumar, Vadlamudi, Gayathri, Obeid, Tarek, Pogue, Jason, Lephart, Paul R., Martin, Emily Toth, Flanagan, Elaine, Rybak, Michael J., and Kaye, Keith

Published
2012
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5. Epidemiology of Vancomycin-Resistant Enterococcus faecalis: a Case-Case-Control Study

Author

Michael J. Rybak, Manoj Das, Venkat Ram Rakesh Mundra, Keith S. Kaye, Rajiv Doddamani, Naveen Kannekanti, Sharan Lohithaswa, Aditya Govindavarjhulla, Sowmya Chidurala, Uma Mahesh Gudur, Dror Marchaim, Deepti Chowdary, Kayoko Hayakawa, Harish Pulluru, Khaled Alshabani, Praveen Vemuri, Emily T. Martin, Jason M. Pogue, Shiva Prasad Shashidharan, Sreelatha Diviti, Pradeep Bathina, Hari Kakarlapudi, Harish Guddati, Raviteja R. Guddeti, Krishna Sukayogula, Rohan Policherla, Deepika Reddy Abbadi, Sarika Bai, Melwin Joseph, Ashwini Mallad, Paul R. Lephart, and Mohan Palla

Subjects
Male, Michigan, medicine.medical_specialty, medicine.drug_class, Cephalosporin, Comorbidity, Microbial Sensitivity Tests, Drug resistance, medicine.disease_cause, Enterococcus faecalis, Epidemiology and Surveillance, Microbiology, Cohort Studies, Immunocompromised Host, Catheters, Indwelling, Risk Factors, Drug Resistance, Multiple, Bacterial, Internal medicine, Epidemiology, Diabetes Mellitus, medicine, Humans, Infection control, Pharmacology (medical), Gram-Positive Bacterial Infections, Aged, Aged, 80 and over, Pharmacology, biology, business.industry, Age Factors, Case-control study, Vancomycin Resistance, Middle Aged, biology.organism_classification, Anti-Bacterial Agents, Cephalosporins, Infectious Diseases, Staphylococcus aureus, Case-Control Studies, Female, business, Fluoroquinolones, Enterococcus faecium
Abstract

Although much is known about vancomycin-resistant (VR) Enterococcus faecium , little is known about the epidemiology of VR Enterococcus faecalis . The predilection of VR E. faecalis to transfer the vancomycin resistance determinant to Staphylococcus aureus is much greater than that of VR E. faecium . The epidemiology of VR E. faecalis has important implications regarding the emergence of vancomycin-resistant S. aureus (VRSA); 8 of 13 reported VRSA cases have been from Michigan. A retrospective case-case-control study was conducted at the Detroit Medical Center, located in southeastern Michigan. Unique patients with VR E. faecalis infection were matched to patients with strains of vancomycin-susceptible (VS) E. faecalis and to uninfected controls at a 1:1:1 ratio. Five hundred thirty-two VR E. faecalis cases were identified and were matched to 532 VS E. faecalis cases and 532 uninfected controls. The overall mean age of the study cohort ( n = 1,596) was 63.0 ± 17.4 years, and 747 (46.8%) individuals were male. Independent predictors for the isolation of VR E. faecalis (but not VS E. faecalis ) compared to uninfected controls were an age of ≥65 years, nonhome residence, diabetes mellitus, peripheral vascular disease, exposure to cephalosporins and fluoroquinolones in the prior 3 months, and immunosuppressive status. Invasive procedures and/or surgery, chronic skin ulcers, and indwelling devices were risk factors for both VR E. faecalis and VS E. faecalis isolation. Cephalosporin and fluoroquinolone exposures were unique, independent predictors for isolation of VR E. faecalis . A majority of case patients had VR E. faecalis present at the time of admission. Control of VR E. faecalis , and ultimately VRSA, will likely require regional efforts focusing on infection prevention and antimicrobial stewardship.

Published
2013
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6. Risk Factors for Vancomycin-resistant Enterococcus faecalis bacteremia: A Case-Case-Control Study

Author

Kayoko Hayakawa, Dror Marchaim, Mohan B. Palla, Uma Mahesh, Harish Pulluru, Kyeong Pyo Lee, Srinivasa Kamatam, Manit Singla, Mayan Ajamoughli, Pradeep Bathina, Khaled Alshabani, Aditya Govindavarjhulla, Ashwini Mallad, Kevin Ho, Deepika Reddy Abbadi, Deepti Chowdary, Hari Kakarlapudi, Harish Guddati, Manoj Das, Naveen Kannekanti, Balaji Ramasamy, Amber Khan, Praveen Vemuri, Rajiv Doddamani, Venkat Ram Rakesh Mundra, Raviteja Reddy Guddeti, Rohan Policherla, Sarika Bai, Sharan Lohithaswa, Shiva Prasad Shashidharan, Sowmya Chidurala, Sreelatha Diviti, Dipenkumar Patel, Gayathri Vadlamudi, Tarek Obeid, Jason Pogue, Paul R. Lephart, Emily Toth Martin, Elaine Flanagan, Michael J. Rybak, and Keith Kaye

Subjects
Infectious Diseases, Epidemiology, business.industry, Health Policy, Bacteremia, Public Health, Environmental and Occupational Health, Case-control study, medicine, medicine.disease, business, Microbiology, Vancomycin resistant Enterococcus faecalis
Published
2012
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7. Risk Factors for the Isolation of Vancomycin-Resistant Enterococcus Faecalis from Wound Site: A Case-Case Control Analysis

Author

Harish Guddati, Sowmya Chidurala, Manit Singla, Jason M. Pogue, Uma Mahesh, Raviteja R. Guddeti, Mayan Ajamoughli, Venkat Ram Rakesh Mundra, Sreelatha Diviti, Tarek Obeid, Kevin Ki-Wai Ho, Balaji Ramasamy, Aditya Govindavarjhulla, Elaine Flanagan, Deepika Reddy Abbadi, Sharan Lohithaswa, Rajiv Doddamani, Shiva Prasad Shashidharan, Harish Pulluru, Sarika Bai, Michael J. Rybak, Ashwini Mallad, Manoj Das, Deepti Chowdary, Kyeong Pyo Lee, Srinivasa Kamatam, Mohan Palla, Emily T. Martin, Dipenkumar Patel, Naveen Kannekanti, Khaled Alshabani, Praveen Vemuri, Rohan Policherla, Pradeep Bathina, Hari Kakarlapudi, Keith S. Kaye, Amber Khan, Kayoko Hayakawa, Gayathri Vadlamudi, Paul R. Lephart, and Dror Marchaim

Subjects
Wound site, Infectious Diseases, Isolation (health care), Epidemiology, business.industry, Health Policy, Public Health, Environmental and Occupational Health, Case control analysis, Medicine, business, Vancomycin resistant Enterococcus faecalis, Microbiology
Published
2012
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8. Epidemiology of Vancomycin-Resistant Enterococcus faecalis: a Case-Case-Control Study

Author

Hayakawa, Kayoko, primary, Marchaim, Dror, additional, Palla, Mohan, additional, Gudur, Uma Mahesh, additional, Pulluru, Harish, additional, Bathina, Pradeep, additional, Alshabani, Khaled, additional, Govindavarjhulla, Aditya, additional, Mallad, Ashwini, additional, Abbadi, Deepika Reddy, additional, Chowdary, Deepti, additional, Kakarlapudi, Hari, additional, Guddati, Harish, additional, Das, Manoj, additional, Kannekanti, Naveen, additional, Vemuri, Praveen, additional, Doddamani, Rajiv, additional, Mundra, Venkat Ram Rakesh, additional, Guddeti, Raviteja Reddy, additional, Policherla, Rohan, additional, Bai, Sarika, additional, Lohithaswa, Sharan, additional, Shashidharan, Shiva Prasad, additional, Chidurala, Sowmya, additional, Diviti, Sreelatha, additional, Sukayogula, Krishna, additional, Joseph, Melwin, additional, Pogue, Jason M., additional, Lephart, Paul R., additional, Martin, Emily T., additional, Rybak, Michael J., additional, and Kaye, Keith S., additional

Published
2013
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9. Epidemiology of Vancomycin-Resistant Enterococcus faecalis: a Case-Case-Control Study

Author

Hayakawa, Kayoko, Marchaim, Dror, Palla, Mohan, Gudur, Uma Mahesh, Pulluru, Harish, Bathina, Pradeep, Alshabani, Khaled, Govindavarjhulla, Aditya, Mallad, Ashwini, Abbadi, Deepika Reddy, Chowdary, Deepti, Kakarlapudi, Hari, Guddati, Harish, Das, Manoj, Kannekanti, Naveen, Vemuri, Praveen, Doddamani, Rajiv, Mundra, Venkat Ram Rakesh, Guddeti, Raviteja Reddy, Policherla, Rohan, Bai, Sarika, Lohithaswa, Sharan, Shashidharan, Shiva Prasad, Chidurala, Sowmya, Diviti, Sreelatha, Sukayogula, Krishna, Joseph, Melwin, Pogue, Jason M., Lephart, Paul R., Martin, Emily T., Rybak, Michael J., and Kaye, Keith S.

Abstract

ABSTRACTAlthough much is known about vancomycin-resistant (VR) Enterococcus faecium, little is known about the epidemiology of VR Enterococcus faecalis. The predilection of VR E. faecalisto transfer the vancomycin resistance determinant to Staphylococcus aureusis much greater than that of VR E. faecium. The epidemiology of VR E. faecalishas important implications regarding the emergence of vancomycin-resistant S. aureus(VRSA); 8 of 13 reported VRSA cases have been from Michigan. A retrospective case-case-control study was conducted at the Detroit Medical Center, located in southeastern Michigan. Unique patients with VR E. faecalisinfection were matched to patients with strains of vancomycin-susceptible (VS) E. faecalisand to uninfected controls at a 1:1:1 ratio. Five hundred thirty-two VR E. faecaliscases were identified and were matched to 532 VS E. faecaliscases and 532 uninfected controls. The overall mean age of the study cohort (n= 1,596) was 63.0 ± 17.4 years, and 747 (46.8%) individuals were male. Independent predictors for the isolation of VR E. faecalis(but not VS E. faecalis) compared to uninfected controls were an age of ≥65 years, nonhome residence, diabetes mellitus, peripheral vascular disease, exposure to cephalosporins and fluoroquinolones in the prior 3 months, and immunosuppressive status. Invasive procedures and/or surgery, chronic skin ulcers, and indwelling devices were risk factors for both VR E. faecalisand VS E. faecalisisolation. Cephalosporin and fluoroquinolone exposures were unique, independent predictors for isolation of VR E. faecalis. A majority of case patients had VR E. faecalispresent at the time of admission. Control of VR E. faecalis, and ultimately VRSA, will likely require regional efforts focusing on infection prevention and antimicrobial stewardship.

Published
2012
Full Text
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