21,327 results on '"Goulding"'
Search Results
2. Index
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Goulding CJ, Gill K.
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- 2023
3. Conclusion
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Goulding CJ, Gill K.
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- 2023
4. Bibliography
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Goulding CJ, Gill K.
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- 2023
5. Appendix. Mary, Mother of Mercy
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Goulding CJ, Gill K.
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- 2023
6. Postscript
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Goulding CJ, Gill K.
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- 2023
7. Four The Trinitarian Horizon
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Goulding CJ, Gill K.
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- 2023
8. Five Engaging Ecclesiological Ramifications
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Goulding CJ, Gill K.
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- 2023
9. Three Specific Christological Underpinnings of Mercy
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Goulding CJ, Gill K.
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- 2023
10. Two Ignatian Influence on Pope Francis
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Goulding CJ, Gill K.
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- 2023
11. Acknowledgments
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Goulding CJ, Gill K.
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- 2023
12. One Foundations for a Dialogue on Mercy
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Goulding CJ, Gill K.
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- 2023
13. Half Title Page, Title Page, Copyright
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Goulding CJ, Gill K.
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- 2023
14. Geometry and the Gods: Theurgy in Proclus’s Commentary on the First Book of Euclid’s Elements
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Goulding, Robert
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- 2022
15. Consensus Guidelines on Interventional Therapies for Knee Pain (STEP Guidelines) from the American Society of Pain and Neuroscience
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Hunter CW, Deer TR, Jones MR, Chang Chien GC, D'Souza RS, Davis T, Eldon ER, Esposito MF, Goree JH, Hewan-Lowe L, Maloney JA, Mazzola AJ, Michels JS, Layno-Moses A, Patel S, Tari J, Weisbein JS, Goulding KA, Chhabra A, Hassebrock J, Wie C, Beall D, Sayed D, and Strand N
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knee ,knee pain ,genicular nerve ,ablation ,regenerative medicine ,platelet rich plasma. dorsal root ganglion ,peripheral nerve stimulation ,Medicine (General) ,R5-920 - Abstract
Corey W Hunter,1,2 Timothy R Deer,3 Mark R Jones,4 George Chiang Chien,5 Ryan S D’Souza,6 Timothy Davis,7 Erica R Eldon,2 Michael F Esposito,8 Johnathan H Goree,9 Lissa Hewan-Lowe,2 Jillian A Maloney,10 Anthony J Mazzola,2 John S Michels,4 Annie Layno-Moses,7 Shachi Patel,11 Jeanmarie Tari,1 Jacqueline S Weisbein,12 Krista A Goulding,13 Anikar Chhabra,13 Jeffrey Hassebrock,13 Chris Wie,10 Douglas Beall,14 Dawood Sayed,15 Natalie Strand10 1Ainsworth Institute of Pain Management, New York, NY, USA; 2Department of Rehabilitation & Human Performance, Icahn School of Medicine at Mount Sinai, New York, NY, USA; 3The Spine and Nerve Center of the Virginias, Charleston, WV, USA; 4Interventional Spine and Pain, Dallas, TX, USA; 5County Medical Center, Ventura, CA, USA; 6Department of Anesthesiology, Mayo Clinic, Rochester, MN, USA; 7Source Healthcare, Santa Monica, CA, USA; 8Interventional Spine and Pain Institute, Vero Beach, FL, USA; 9Department of Anesthesiology, University of Arkansas for Medical Sciences, Little Rock, AR, USA; 10Department of Anesthesiology, Division of Pain Medicine, Mayo Clinic, Phoenix, AZ, USA; 11Delmarva Pain and Spine Center, Newark, DE, USA; 12Napa Valley Orthopaedic Medical Group, Napa, CA, USA; 13Department of Orthopedic Surgery, Mayo Clinic, Phoenix, AZ, USA; 14Comprehensive Specialty Care, Oklahoma City, OK, USA; 15Department of Anesthesiology, Division of Pain Medicine, University of Kansas Medical Center, Kansas City, KS, USACorrespondence: Corey W Hunter, Email chunter@ainPain.comAbstract: Knee pain is second only to the back as the most commonly reported area of pain in the human body. With an overall prevalence of 46.2%, its impact on disability, lost productivity, and cost on healthcare cannot be overlooked. Due to the pervasiveness of knee pain in the general population, there are no shortages of treatment options available for addressing the symptoms. Ranging from physical therapy and pharmacologic agents to interventional pain procedures to surgical options, practitioners have a wide array of options to choose from – unfortunately, there is no consensus on which treatments are “better” and when they should be offered in comparison to others. While it is generally accepted that less invasive treatments should be offered before more invasive ones, there is a lack of agreement on the order in which the less invasive are to be presented. In an effort to standardize the treatment of this extremely prevalent pathology, the authors present an all-encompassing set of guidelines on the treatment of knee pain based on an extensive literature search and data grading for each of the available alternative that will allow practitioners the ability to compare and contrast each option.Keywords: knee, knee pain, genicular nerve, ablation, regenerative medicine, platelet-rich plasma, dorsal root ganglion, peripheral nerve stimulation
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- 2022
16. Personal Collections and Personal Information Management in the Family Context
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Krtalić, Maja, Dinneen, Jesse David, Liew, Chern Li, and Goulding, Anne
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- 2022
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17. An unambiguous AGN and a Balmer break in an Ultraluminous Little Red Dot at z=4.47 from Ultradeep UNCOVER and All the Little Things Spectroscopy
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Labbe, Ivo, Greene, Jenny E., Matthee, Jorryt, Treiber, Helena, Kokorev, Vasily, Miller, Tim B., Kramarenko, Ivan, Setton, David J., Ma, Yilun, Goulding, Andy D., Bezanson, Rachel, Naidu, Rohan P., Williams, Christina C., Atek, Hakim, Brammer, Gabriel, Cutler, Sam E., Chemerynska, Iryna, Cloonan, Aidan P., Dayal, Pratika, de Graaff, Anna, Fudamoto, Yoshinobu, Fujimoto, Seiji, Furtak, Lukas J., Glazebrook, Karl, Heintz, Kasper E., Leja, Joel, Marchesini, Danilo, Nanayakkara, Themiya, Nelson, Erica J., Oesch, Pascal A., Pan, Richard, Price, Sedona H., Shivaei, Irene, Sobral, David, Suess, Katherine A., van Dokkum, Pieter, Wang, Bingjie, Weaver, John R., Whitaker, Katherine E., and Zitrin, Adi
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Astrophysics - Astrophysics of Galaxies - Abstract
We present a detailed exploration of the most optically-luminous Little Red Dot ($L_{H\alpha}=10^{44}$erg/s, $L_V=10^{45}$erg/s, F444W=22AB) found to date. Located in the Abell 2744 field, source A744-45924 was observed by NIRSpec/PRISM with ultradeep spectroscopy reaching SNR$\sim$100pix$^{-1}$, high-resolution 3-4 micron NIRCam/Grism spectroscopy, and NIRCam Medium Band imaging. The NIRCam spectra reveal high rest-frame EW $W_{H\alpha,0,broad}>800$\r{A}, broad H$\alpha$ emission (FWHM$\sim$4500 km/s), on top of narrow, complex absorption. NIRSpec data show exceptionally strong rest-frame UV to NIR Fe II emission ($W_{FeII-UV,0}\sim$340\r{A}), N IV]$\lambda\lambda$1483,1486 and N III]$\lambda$1750, and broad NIR O I $\lambda$8446 emission. The spectra unambiguously demonstrate a broad-line region associated with an inferred $M_{BH}\sim10^9M_\odot$ supermassive black hole embedded in dense gas, which might explain a non-detection in ultradeep Chandra X-ray data (>$10\times$ underluminous relative to broad $L_{H\alpha}$). Strong UV Nitrogen lines suggest supersolar N/O ratios due to rapid star formation or intense radiation near the AGN. The continuum shows a clear Balmer break at rest-frame 3650\r{A}, which cannot be accounted for by an AGN power-law alone. A stellar population model produces an excellent fit with a reddened Balmer break and implying a massive ($M_*\sim8\times10^{10}M_\odot$), old $\sim$500 Myr, compact stellar core, among the densest stellar systems known ($\rho\sim3\times10^6M_\odot$/pc$^2$ for $R_{e,opt}=70\pm10$ pc), and AGN emission with extreme intrinsic EW $W_{H\alpha,0}\gg$1000\r{A}. However, although high $M_*$ and $M_{BH}$ are supported by evidence of an overdensity containing 40 galaxies at $z=4.41-4.51$, deep high-resolution spectroscopy is required to confirm stellar absorption and rule out that dense gas around the AGN causes the Balmer break instead., Comment: 28 pages,10 figures, submitted to ApJ
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- 2024
18. It seems as if Wayne Brown doesn't now what a library is!
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Goulding, Anne
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- 2023
19. Cross-correlation of Luminous Red Galaxies with ML-selected AGN in HSC-SSP II: AGN classification and clustering with DESI spectroscopy
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Rosado, Rodrigo Córdova, Goulding, Andy D., Greene, Jenny E., Kokron, Nickolas, Strauss, Michael A., Hahn, ChangHoon, Petter, Grayson C., and Hickox, Ryan C.
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Astrophysics - Astrophysics of Galaxies - Abstract
An unresolved question in studies of active galactic nuclei (AGN) is whether their different classes probe different evolutionary stages of black hole--host galaxy interaction. We present the projected two-point cross-correlation function between a sample of Dark Energy Spectroscopic Instrument (DESI)-matched AGN selected from Hyper Suprime-Cam Subaru Strategic Program (HSC-SSP) optical + Wide-field Infrared Survey Explorer ($WISE$) mid-IR photometry, and DESI-designated luminous red galaxies, for $z\in 0.5-1.0$. The total overlap area is 43.4 deg$^2$, including $\sim27,000$ spectroscopic LRGs in our redshift range. We visually classified 1,991 matched HSC-DESI objects in our redshift range, spectroscopically confirming that 1,517 ($76\%$) of them are AGN. Of these 1,517 objects, $73\%$ are broad-line AGN, $27\%$ are obscured AGN. We infer that the parent HSC+$WISE$ AGN catalog has a number density of at least $\sim 240$ deg$^{-2}$, confirming it is one of the most complete optical/infrared AGN catalog to date. We investigate the AGN clustering as a function of the spectroscopic classification and infer the halo mass for each sample. The inferred average mass of the halos $\langle M_h\rangle$ that host unobscured broad-line AGN ($M_h \approx 10^{13.4}h^{-1}M_\odot$) is $\sim 5.5\times$ larger than the halos that host obscured AGN ($M_h \approx 10^{12.6}\, h^{-1}M_\odot$), at $2.8\sigma$ significance, in the same sense as our prior work based on photometric redshifts. This suggests that we may relax our concerns about systematic shifts in the inferred redshift distribution producing this halo mass difference. While we do not yet find statistically significant spectroscopic evidence that unobscured AGN reside in more massive halos than their obscured counterparts, further analyses are necessary to distinguish if more complex evolutionary histories are needed to model these AGN populations., Comment: 27 pages, 12 figures, submitted to ApJ
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- 2024
20. First results from the JWST Early Release Science Program Q3D: AGN photoionization and shock4 ionization in a red quasar at z = 0.45
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Sankar, Swetha, Zakamska, Nadia L., Rupke, David S. N., Liu, Weizhe, Wylezalek, Dominika, Veilleux, Sylvain, Bertemes, Caroline, Diachenko, Nadiia, Chen, Yu-Ching, Ishikawa, Yuzo, Vayner, Andrey, Nesvadba, Nicole P. H., Liu, Guilin, Goulding, Andy D., and Lutz, Dieter
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Astrophysics - Astrophysics of Galaxies - Abstract
Red quasars, often associated with potent [OIII] outflows on both galactic and circumgalactic scales, may play a pivotal role in galactic evolution and black hole feedback. In this work, we explore the [FeII] emission in one such quasar at redshift z = 0.4352, F2M J110648.32+480712.3, using the integral field unit (IFU) mode of the Near Infrared Spectrograph (NIRSpec) aboard the James Webb Space Telescope (JWST). Our observations reveal clumpy [FeII] gas located to the south of the quasar. By comparing the kinematics of [FeII] and [OIII], we find that the clumpy [FeII] gas in the southeast and southwest aligns with the outflow, exhibiting similar median velocities up to v_50 ~ 1200 km/s and high velocity widths W_80 > 1000 km/s. In contrast, the [FeII] gas to the south shows kinematics inconsistent with the outflow, with W_80 ~ 500 km/s, significantly smaller than the [OIII] at the same location, suggesting that the [FeII] may be confined within the host galaxy. Utilizing standard emission-line diagnostic ratios, we map the ionization sources of the gas. According to the MAPPINGS III shock models for [FeII]/Pabeta, the regions to the southwest and southeast of the quasar are primarily photoionized. Conversely, the [FeII] emission to the south is likely excited by shocks generated by the back-pressure of the outflow on the galaxy disk, a direct signature of the impact of the quasar on its host.
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- 2024
21. First results from the JWST Early Release Science Program Q3D: The Fast Outflow in a Red Quasar at z=0.44
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Liu, Weizhe, Veilleux, Sylvain, Sankar, Swetha, Rupke, David S. N., Zakamska, Nadia L., Wylezalek, Dominika, Vayner, Andrey, Bertemes, Caroline, Chen, Yu-Ching, Ishikawa, Yuzo, Greene, Jenny E., Heckman, Timothy, Liu, Guilin, Chen, Hsiao-Wen, Lutz, Dieter, Johnson, Sean D., Nesvadba, Nicole P. H., Ogle, Patrick, Diachenko, Nadiia, Goulding, Andy D., Hainline, Kevin N., Hamann, Fred, Lim, Hui Xian Grace, Lützgendorf, Nora, Mainieri, Vincenzo, McCrory, Ryan, Murphree, Grey, Sturm, Eckhard, and Whitesell, Lillian
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Astrophysics - Astrophysics of Galaxies - Abstract
Quasar feedback may play a key role in the evolution of massive galaxies. The dust-reddened quasar, F2M110648.35$+$480712 at $z = 0.4352$ is one of the few cases at its redshift that exhibits powerful quasar feedback through bipolar outflows. Our new observation with the integral field unit mode of Near-infrared Spectrograph onboard JWST opens a new window to examine this spectacular outflow through Pa$\alpha$ emission line with $\sim$3$\times$ better spatial resolution than previous work. The morphology and kinematics of the Pa$\alpha$ nebula confirm the existence of a bipolar outflow extending on a scale of $\sim$17$\times$14 kpc and with a velocity reaching $\sim$1100 km s$^{-1}$. The higher spatial resolution of our new observation leads to more reliable measurements of outflow kinematics. Considering only the spatially resolved outflow and assuming an electron density of 100 cm$^{-2}$, the mass, momentum and kinetic energy outflow rates are $\sim$50-210 M$_{\odot}$ yr$^{-1}$, $\sim$0.3-1.7$\times$10$^{36}$ dynes ($\sim$14-78\% of the quasar photon momentum flux) and $\sim$0.16-1.27$\times$10$^{44}$ erg s$^{-1}$ ($\sim$0.02-0.20\% of the quasar bolometric luminosity), respectively. The local instantaneous outflow rates generally decrease radially. We infer that the quasar is powerful enough to drive the outflow, while stellar processes cannot be overlooked as a contributing energy source. The mass outflow rate is $\sim$0.4-1.5 times the star formation rate, and the ratio of kinetic energy outflow rate to the quasar bolometric luminosity is comparable to the minimum value required for negative quasar feedback in simulations. This outflow may help regulate the star formation activity within the system to some extent., Comment: 14 pages, 6 figures, 1 table, ApJ in review
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- 2024
22. UNCOVER: 404 Error -- Models Not Found for the Triply Imaged Little Red Dot A2744-QSO1
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Ma, Yilun, Greene, Jenny E., Setton, David J., Volonteri, Marta, Leja, Joel, Wang, Bingjie, Bezanson, Rachel, Brammer, Gabriel, Cutler, Sam E., Dayal, Pratika, van Dokkum, Pieter, Furtak, Lukas J., Glazebrook, Karl, Goulding, Andy D., de Graaff, Anna, Kokorev, Vasily, Labbe, Ivo, Pan, Richard, Price, Sedona H., Weaver, John R., Williams, Christina C., Whitaker, Katherine E., and Zitrin, Adi
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Astrophysics - Astrophysics of Galaxies ,Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
JWST has revealed an abundance of compact, red objects at $z\approx5-8$ dubbed "little red dots" (LRDs), whose SEDs display a faint blue UV continuum followed by a steep rise in the optical. Despite extensive study of their characteristic V-shaped SEDs, the nature of LRDs remains unknown. We present a new analysis of the NIRSpec/PRISM spectrum of A2744-QSO1, a triply imaged LRD at $z=7.04$ from the UNCOVER survey. The spectrum shows a strong Balmer break and broad Balmer emission lines, both of which are difficult to explain with models invoking exclusively AGN or stellar contributions. Our fiducial model decomposes the spectrum into a post-starburst galaxy dominating the UV-optical continuum and a reddened AGN being sub-dominant at all wavelength and contributing at $\sim20\%$ level. However, our most credible model infers a stellar mass of $M_\star\approx 4\times10^9\,\mathrm{M_\odot}$ within a radius of $r_\mathrm{e}<30\,$pc, driving its central density to the highest among observations to date. This high central density could be explained if A2744-QSO-1 is the early-forming core of a modern-day massive elliptical galaxy that later puffed up via the inside-out growth channel. The models also necessitate an unusually steep dust law to preserve the strong break strength, though this steepness may be explained by a deficit of large dust grains. It is also probable that these challenges reflect our ignorance of A2744-QSO1's true nature. Future variability and reverberation mapping studies could help disentangle the galaxy and AGN contribution to the continuum, and deeper redder observations could also unveil the dust properties in LRDs., Comment: 19 pages, 7 figures, 2 tables. Submitted to ApJ. Comments are welcome
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- 2024
23. UNCOVERing the High-Redshift AGN Population Among Extreme UV Line Emitters
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Treiber, Helena, Greene, Jenny, Weaver, John R., Miller, Tim B., Furtak, Lukas J., Setton, David J., Wang, Bingjie, de Graaff, Anna, Bezanson, Rachel, Brammer, Gabriel, Cutler, Sam E., Dayal, Pratika, Feldmann, Robert, Fujimoto, Seiji, Goulding, Andy D., Kokorev, Vasily, Labbe, Ivo, Leja, Joel, Marchesini, Danilo, Nanayakkara, Themiya, Nelson, Erica, Pan, Richard, Price, Sedona H., Siegel, Jared, Suess, Katherine, and Whitaker, Katherine
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Astrophysics - Astrophysics of Galaxies - Abstract
JWST has revealed diverse new populations of high-redshift ($z\sim4-11$) AGN and extreme star-forming galaxies that challenge current models. In this paper, we use rest-frame UV emission-line diagnostics to identify AGN candidates and other exceptional ionizing sources, complementing previous studies predominantly focused on broad-line AGN. In this paper, we use rest-frame UV emission-line diagnostics to identify AGN candidates and other exceptional ionizing sources, complementing previous studies predominantly focused on broad-line AGN. From a parent sample of 205 $\mathrm{z_{spec}}>3$ UNCOVER galaxies with NIRSpec/PRISM follow-up, we identify 12 C IV, He II, and C III] emitters. Leveraging the combined rest-optical and UV coverage of PRISM, we limit the emission-line model space using the sample's [O III]/H$\beta$ distribution, significantly decreasing the overlap between AGN and star-formation models in the UV diagnostics. We then find that the five He II emitters are the strongest AGN candidates, with further support from two [Ne V] detections and one X-ray detection from Chandra. We cannot robustly quantify the AGN fraction in this sample, but we note that close to 20% of $\mathrm{M_{*}>2\times10^{9}\,M_{\odot}}$ parent sample galaxies are AGN candidates. The lower-mass line emitters, which are consistent with both AGN and star-forming photoionization models, have more compact sizes and higher specific star formation rates than the parent sample. Higher-resolution and deeper data on these UV line emitters should provide much stronger constraints on the obscured AGN fraction at $z > 3$., Comment: Submitted to ApJ
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- 2024
24. Cross-correlation of Luminous Red Galaxies with ML-selected AGN in HSC-SSP: Unobscured AGN residing in more massive halos
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Rosado, Rodrigo Córdova, Goulding, Andy D., Greene, Jenny E., Petter, Grayson C., Hickox, Ryan C., Kokron, Nickolas, Strauss, Michael A., Givans, Jahmour J., Toba, Yoshiki, and Henderson, Cassandra Starr
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Astrophysics - Astrophysics of Galaxies - Abstract
Active galactic nuclei (AGN) are the signposts of black hole growth, and likely play an important role in galaxy evolution. An outstanding question is whether AGN of different spectral types indicate different evolutionary stages in the coevolution of black holes and galaxies. We present the angular correlation function between an AGN sample selected from the Hyper Suprime Camera Subaru Strategic Program (HSC-SSP) optical + Wide-field Infrared Survey Explorer (WISE) mid-IR photometry, and a luminous red galaxy (LRG) sample from HSC-SSP. We investigate AGN clustering strength as a function of their luminosity and spectral features across three independent HSC fields totaling $\sim600\,{\rm deg^{2}}$, for $z\in0.6-1.2$ and AGN with $L_{6\mu m}>3\times10^{44}{\rm\,erg\,s^{-1}}$. There are $\sim28,500$ AGN and $\sim1.5$ million LRGs in our primary analysis. We determine the inferred average halo mass for the full AGN sample ($M_h \approx 10^{12.9}h^{-1}M_\odot$), and note that it does not evolve significantly as a function of redshift (over this narrow range) or luminosity. We find that, on average, unobscured AGN ($M_h \approx10^{13.3}h^{-1}M_\odot$) occupy $\sim4.5\times$ more massive halos than obscured AGN ($M_h \approx10^{12.6}h^{-1}M_\odot$), at $5\sigma$ statistical significance using 1-D uncertainties, and at $3\sigma$ using the full covariance matrix, suggesting a physical difference between unobscured and obscured AGN, beyond the line-of-sight viewing angle. Furthermore, we find evidence for a halo mass dependence on reddening level within the Type I AGN population, which could support the existence of a previously claimed dust-obscured phase in AGN-host galaxy coevolution. However, we also find that even quite small systematic shifts in the redshift distributions of the AGN sample could plausibly explain current and previously observed differences in $M_{h}$., Comment: 31 pages, 14 figures, submitted to ApJ
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- 2024
25. The UNCOVER Survey: First Release of Ultradeep JWST/NIRSpec PRISM spectra for ~700 galaxies from z~0.3-13 in Abell 2744
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Price, Sedona H., Bezanson, Rachel, Labbe, Ivo, Furtak, Lukas J., de Graaff, Anna, Greene, Jenny E., Kokorev, Vasily, Setton, David J., Suess, Katherine A., Brammer, Gabriel, Cutler, Sam E., Leja, Joel, Pan, Richard, Wang, Bingjie, Weaver, John R., Whitaker, Katherine E., Atek, Hakim, Burgasser, Adam J., Chemerynska, Iryna, Dayal, Pratika, Feldmann, Robert, Schreiber, Natascha M. Förster, Fudamoto, Yoshinobu, Fujimoto, Seiji, Glazebrook, Karl, Goulding, Andy D., Khullar, Gourav, Kriek, Mariska, Marchesini, Danilo, Maseda, Michael V., Miller, Tim B., Muzzin, Adam, Nanayakkara, Themiya, Nelson, Erica, Oesch, Pascal A., Shipley, Heath, Smit, Renske, Taylor, Edward N., van Dokkum, Pieter, Williams, Christina C., and Zitrin, Adi
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Astrophysics - Astrophysics of Galaxies - Abstract
We present the design and observations of low resolution JWST/NIRSpec PRISM spectroscopy from the Ultradeep NIRSpec and NIRCam ObserVations before the Epoch of Reionization (UNCOVER) Cycle 1 JWST Treasury program. Targets are selected using JWST/NIRCam photometry from UNCOVER and other programs, and cover a wide range of categories and redshifts to ensure the legacy value of the survey. These categories include the first galaxies at $z\gtrsim10$, faint galaxies during the Epoch of Reionization ($z\sim6-8$), high redshift AGN ($z\gtrsim6$), Population III star candidates, distant quiescent and dusty galaxies ($1\lesssim z \lesssim 6$), and filler galaxies sampling redshift--color--magnitude space from $z\sim 0.1-13$. Seven NIRSpec MSA masks across the extended Abell 2744 cluster were observed, along with NIRCam parallel imaging in 8 filters (F090W, F115W, F150W, F200W, F277W, F356W, F410M, F444W, F480M) over a total area of ~26 arcmin$^2$, overlapping existing HST coverage from programs including the Hubble Frontier Fields and BUFFALO. We successfully observed 553 objects down to $m_{\mathrm{F444W}}\sim30\mathrm{AB}$, and by leveraging mask overlaps, we reach total on-target exposure times ranging from 2.4-16.7h. We demonstrate the success rate and distribution of confirmed redshifts, and also highlight the rich information revealed by these ultradeep spectra for a subset of our targets. An updated lens model of Abell 2744 is also presented, including 14 additional spectroscopic redshifts and finding a total cluster mass of $M_{\mathrm{SL}}=(2.1\pm0.3)\times10^{15}\,\mathrm{M}_{\odot}$. We publicly release reduced 1D and 2D spectra for all objects observed in Summer 2023 along with a spectroscopic redshift catalog and the updated lens model of the cluster (https://jwst-uncover.github.io/DR4.html)., Comment: 19 pages, 9 figures, 4 tables, submitted to ApJ, comments welcome! Data available at: https://jwst-uncover.github.io/DR4.html (v2: figure format correction)
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- 2024
26. Advanced glycation end-product crosslinking activates a type VI secretion system phospholipase effector protein
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Jensen, Steven J, Cuthbert, Bonnie J, Garza-Sánchez, Fernando, Helou, Colette C, de Miranda, Rodger, Goulding, Celia W, and Hayes, Christopher S
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Biochemistry and Cell Biology ,Biological Sciences ,Diabetes ,2.1 Biological and endogenous factors ,Glycation End Products ,Advanced ,Enterobacter cloacae ,Bacterial Proteins ,Pyruvaldehyde ,Arginine ,Protein Processing ,Post-Translational ,Lysine ,Disulfides - Abstract
Advanced glycation end-products (AGE) are a pervasive form of protein damage implicated in the pathogenesis of neurodegenerative disease, atherosclerosis and diabetes mellitus. Glycation is typically mediated by reactive dicarbonyl compounds that accumulate in all cells as toxic byproducts of glucose metabolism. Here, we show that AGE crosslinking is harnessed to activate an antibacterial phospholipase effector protein deployed by the type VI secretion system of Enterobacter cloacae. Endogenous methylglyoxal reacts with a specific arginine-lysine pair to tether the N- and C-terminal α-helices of the phospholipase domain. Substitutions at these positions abrogate both crosslinking and toxic phospholipase activity, but in vitro enzyme function can be restored with an engineered disulfide that covalently links the N- and C-termini. Thus, AGE crosslinking serves as a bona fide post-translation modification to stabilize phospholipase structure. Given the ubiquity of methylglyoxal in prokaryotic and eukaryotic cells, these findings suggest that glycation may be exploited more generally to stabilize other proteins. This alternative strategy to fortify tertiary structure could be particularly advantageous in the cytoplasm, where redox potentials preclude disulfide bond formation.
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- 2024
27. The Digital Participation Lab at Te Herenga Waka
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Goulding, Anne
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- 2022
28. Dust and Power: Unravelling the merger - active galactic nucleus connection in the second half of cosmic history
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La Marca, A., Margalef-Bentabol, B., Wang, L., Gao, F., Goulding, A. D., Martin, G., Rodriguez-Gomez, V., Trager, S. C., Yang, G., Davé, R., and Dubois, Y.
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Astrophysics - Astrophysics of Galaxies - Abstract
Galaxy mergers represent a fundamental physical process under hierarchical structure formation, but their role in triggering AGNs is still unclear. We aim to investigate the merger-AGN connection using state-of-the-art observations and novel methods in detecting mergers and AGNs. We selected stellar mass-limited samples at redshift z<1 from KiDS, focusing on the KiDS-N-W2 field with a wide range of multi-wavelength data. Three AGN types, selected in the MIR, X-ray, and via SED modelling, were analysed. To identify mergers, we used convolutional neural networks trained on two cosmological simulations. We created mass and redshift-matched control samples of non-mergers and non-AGNs. We observe a clear AGN excess (a factor of 2-3) in mergers with respect to non-mergers for the MIR AGNs, and a mild excess for the X-ray and SED AGNs, indicating that mergers could trigger all 3 types but are more connected with the MIR AGNs. About half of the MIR AGNs are in mergers but it is unclear whether mergers are the main trigger. For the X-ray and SED AGNs, mergers are unlikely to be the dominant trigger. We also explore the relation using the continuous AGN fraction $f_{AGN}$ parameter. Mergers exhibit a clear excess of high $f_{AGN}$ values relative to non-mergers, for all AGNs. We unveil the first merger fraction $f_{merg}-f_{AGN}$ relation with two distinct regimes. When the AGN is not dominant, the relation is only mildly increasing or even flat, with the MIR AGNs showing the highest $f_{merg}$. In the regime of very dominant AGNs ($f_{AGN}\geq0.8$), $f_{merg}$ shows a steeply rising trend with increasing $f_{AGN}$ for all AGN types. These trends are also seen when plotted against AGN bolometric luminosity. We conclude that mergers are most connected with dust-obscured AGNs (linked to a fast-growing phase of the SMBH) and are the main or even the sole fuelling mechanism of the most powerful AGNs., Comment: 24 pages, 17 figures, 6 Appendix pages. Public available multi-wavelength catalogue of galaxies. Accepted for publication in A&A
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- 2024
- Full Text
- View/download PDF
29. Rich and diverse molecular gas environments of closely-separated dual quasars viewed by ALMA
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Tang, Shenli, Silverman, John D., Liu, Zhaoxuan, Banerji, Manda, Suzuki, Tomoko, Fujimoto, Seiji, Goulding, Andy, Imanishi, Masatoshi, Kawaguchi, Toshihiro, Bottrell, Connor, Hartwig, Tilman, Jahnke, Knud, Onoue, Masafusa, Schramm, Malte, and Ueda, Yoshihiro
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Astrophysics - Astrophysics of Galaxies - Abstract
We present a study of the molecular gas in five closely-spaced ($R_{\perp}<20$ kpc) dual quasars ($L_{\rm bol}\gtrsim10^{44}~\mathrm{erg~s}^{-1}$) at redshifts $0.4
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- 2024
30. Quasars can Signpost Supermassive Black Hole Binaries
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Casey-Clyde, J. Andrew, Mingarelli, Chiara M. F., Greene, Jenny E., Goulding, Andy D., Chen, Siyuan, and Trump, Jonathan R.
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Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Astrophysics of Galaxies - Abstract
Supermassive black holes (SMBHs) are found in the centers of massive galaxies, and galaxy mergers should eventually lead to SMBH mergers. Quasar activity has long been associated with galaxy mergers, so here we investigate if supermassive black hole binaries (SMBHBs) are preferentially found in quasars. Our multimessenger investigation folds together a gravitational wave background signal from NANOGrav, a sample of periodic AGN candidates from the Catalina Real-Time Transient Survey, and a quasar mass function, to estimate an upper limit on the fraction of quasars which could host a SMBHB. We find at 95\% confidence that quasars are at most seven times as likely to host a SMBHB as a random galaxy. Quasars should therefore be prioritized as targets for SMBHB searches in pulsar timing arrays., Comment: 9 pages, 5 figures, 1 appendix
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- 2024
31. A Smartphone-Based Self-management Intervention for Bipolar Disorder (LiveWell): User-Centered Development Approach
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Jonathan, Geneva K, Dopke, Cynthia A, Michaels, Tania, Bank, Andrew, Martin, Clair R, Adhikari, Krina, Krakauer, Rachel L, Ryan, Chloe, McBride, Alyssa, Babington, Pamela, Frauenhofer, Ella, Silver, Jamilah, Capra, Courtney, Simon, Melanie, Begale, Mark, Mohr, David C, and Goulding, Evan H
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Psychology ,BF1-990 - Abstract
BackgroundBipolar disorder is a serious mental illness that results in significant morbidity and mortality. Pharmacotherapy is the primary treatment for bipolar disorder; however, adjunctive psychotherapy can help individuals use self-management strategies to improve outcomes. Yet access to this therapy is limited. Smartphones and other technologies have the potential to increase access to therapeutic strategies that enhance self-management while simultaneously providing real-time user feedback and provider alerts to augment care. ObjectiveThis paper describes the user-centered development of LiveWell, a smartphone-based self-management intervention for bipolar disorder, to contribute to and support the ongoing improvement and dissemination of technology-based mental health interventions. MethodsIndividuals with bipolar disorder first participated in a field trial of a simple smartphone app for self-monitoring of behavioral targets. To develop a complete technology-based intervention for bipolar disorder, this field trial was followed by design sessions, usability testing, and a pilot study of a smartphone-based self-management intervention for bipolar disorder. Throughout all phases of development, intervention revisions were made based on user feedback. ResultsThe core of the LiveWell intervention consists of a daily self-monitoring tool, the Daily Check-in. This self-monitoring tool underwent multiple revisions during the user-centered development process. Daily Check-in mood and thought rating scales were collapsed into a single wellness rating scale to accommodate user development of personalized scale anchors. These anchors are meant to assist users in identifying early warning signs and symptoms of impending episodes to take action based on personalized plans. When users identified personal anchors for the wellness scale, the anchors most commonly reflected behavioral signs and symptoms (40%), followed by cognitive (25%), mood (15%), physical (10%), and motivational (7%) signs and symptoms. Changes to the Daily Check-in were also made to help users distinguish between getting adequate sleep and keeping a regular routine. At the end of the pilot study, users reported that the Daily Check-in made them more aware of early warning signs and symptoms and how much they were sleeping. Users also reported that they liked personalizing their anchors and plans and felt this process was useful. Users experienced some difficulties with developing, tracking, and achieving target goals. Users also did not consistently follow up with app recommendations to contact providers when Daily Check-in data suggested they needed additional assistance. As a result, the human support roles for the technology were expanded beyond app use support to include support for self-management and clinical care communication. The development of these human support roles was aided by feedback on the technology's usability from the users and the coaches who provided the human support. ConclusionsUser input guided the development of intervention content, technology, and coaching support for LiveWell. Users valued the provision of monitoring tools and the ability to personalize plans for staying well, supporting the role of monitoring and personalization as important features of digital mental health technologies. Users also valued human support of the technology in the form of a coach, and user difficulties with aspects of self-management and care-provider communication led to an expansion of the coach's support roles. Obtaining feedback from both users and coaches played an important role in the development of both the LiveWell technology and human support. Attention to all stakeholders involved in the use of mental health technologies is essential for optimizing intervention development.
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- 2021
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32. Development of Coaching Support for LiveWell: A Smartphone-Based Self-Management Intervention for Bipolar Disorder
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Dopke, Cynthia A, McBride, Alyssa, Babington, Pamela, Jonathan, Geneva K, Michaels, Tania, Ryan, Chloe, Duffecy, Jennifer, Mohr, David C, and Goulding, Evan H
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Medicine - Abstract
Despite effective pharmacological treatment, bipolar disorder is a leading cause of disability due to recurrence of episodes, long episode durations, and persistence of interepisode symptoms. While adding psychotherapy to pharmacotherapy improves outcomes, the availability of adjunctive psychotherapy is limited. To extend the accessibility and functionality of psychotherapy for bipolar disorder, we developed LiveWell, a smartphone-based self-management intervention. Unfortunately, many mental health technology interventions suffer from high attrition rates, with users rapidly failing to maintain engagement with the intervention technology. Human support reduces this commonly observed engagement problem but does not consistently improve clinical and recovery outcomes. To facilitate ongoing efforts to develop human support for digital mental health technologies, this paper describes the design decisions, theoretical framework, content, mode, timing of delivery, and the training and supervision for coaching support of the LiveWell technology. This support includes clearly defined and structured roles that aim to encourage the use of the technology, self-management strategies, and communication with care providers. A clear division of labor is established between the coaching support roles and the intervention technology to allow lay personnel to serve as coaches and thereby maximize accessibility to the LiveWell intervention.
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- 2021
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33. Geographical Distribution of Atmospheric Nitrogen Deposition in China and Its Response to Emission Control Policy
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Wen, Zhang, Yu, Ziyin, Si, Ruotong, Xu, Wen, Wang, Kai, Liu, Lei, Tang, Aohan, Zhang, Fusuo, Keith, Goulding, and Liu, Xuejun
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- 2024
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34. Machine learning predicts peak oxygen uptake and peak power output for customizing cardiopulmonary exercise testing using non-exercise features
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Wenzel, Charlotte, Liebig, Thomas, Swoboda, Adrian, Smolareck, Rika, Schlagheck, Marit L., Walzik, David, Groll, Andreas, Goulding, Richie P., and Zimmer, Philipp
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- 2024
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35. Tule Lake: Learning from Places of Exception in a Climate of Fear
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Goulding, Cathlin
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- 2017
36. Medium Bands, Mega Science: a JWST/NIRCam Medium-Band Imaging Survey of Abell 2744
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Suess, Katherine A., Weaver, John R., Price, Sedona H., Pan, Richard, Wang, Bingjie, Bezanson, Rachel, Brammer, Gabriel, Cutler, Sam E., Labbe, Ivo, Leja, Joel, Williams, Christina C., Whitaker, Katherine E., Dayal, Pratika, de Graaff, Anna, Feldmann, Robert, Franx, Marijn, Fudamoto, Yoshinobu, Fujimoto, Seiji, Furtak, Lukas J., Goulding, Andy D., Greene, Jenny E., Khullar, Gourav, Kokorev, Vasily, Kriek, Mariska, Lorenz, Brian, Marchesini, Danilo, Maseda, Michael V., Matthee, Jorryt, Miller, Tim B., Mitsuhashi, Ikki, Mowla, Lamiya A., Muzzin, Adam, Naidu, Rohan P., Nanayakkara, Themiya, Nelson, Erica J., Oesch, Pascal A., Setton, David J., Shipley, Heath, Smit, Renske, Spilker, Justin S., van Dokkum, Pieter, and Zitrin, Adi
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Astrophysics - Astrophysics of Galaxies - Abstract
In this paper, we describe the "Medium Bands, Mega Science" JWST Cycle 2 survey (JWST-GO-4111) and demonstrate the power of these data to reveal both the spatially-integrated and spatially-resolved properties of galaxies from the local universe to the era of cosmic dawn. Executed in November 2023, MegaScience obtained ~30 arcmin^2 of deep multiband NIRCam imaging centered on the z~0.3 Abell 2744 cluster, including eleven medium-band filters and the two shortest-wavelength broad-band filters, F070W and F090W. Together, MegaScience and the UNCOVER Cycle 1 treasury program provide a complete set of deep (~28-30 mag) images in all NIRCam medium- and broad-band filters. This unique dataset allows us to precisely constrain photometric redshifts, map stellar populations and dust attenuation for large samples of distant galaxies, and examine the connection between galaxy structures and formation histories. MegaScience also includes ~17 arcmin^2 of NIRISS parallel imaging in two broad-band and four medium-band filters from 0.9-4.8um, expanding the footprint where robust spectral energy distribution (SED) fitting is possible. We provide example SEDs and multi-band cutouts at a variety of redshifts, and use a catalog of JWST spectroscopic redshifts to show that MegaScience improves both the scatter and catastrophic outlier rate of photometric redshifts by factors of 2-3. Additionally, we demonstrate the spatially-resolved science enabled by MegaScience by presenting maps of the [OIII] line emission and continuum emission in three spectroscopically-confirmed z>6 galaxies. We show that line emission in reionization-era galaxies can be clumpy, extended, and spatially offset from continuum emission, implying that galaxy assembly histories are complex even at these early epochs. We publicly release fully reduced mosaics and photometric catalogs for both the NIRCam primary and NIRISS parallel fields., Comment: 21 pages, 10 figures. Fully reduced imaging, photometric catalogs, and photometric redshift fits publicly available at https://jwst-uncover.github.io/megascience/
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- 2024
37. Estimating Galaxy Parameters with Self-Organizing Maps and the Effect of Missing Data
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La Torre, Valentina, Sajina, Anna, Goulding, Andy D., Marchesini, Danilo, Bezanson, Rachel, Pearl, Alan N., and Sodré Jr, Laerte
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Astrophysics - Astrophysics of Galaxies - Abstract
The current and upcoming large data volume galaxy surveys require the use of machine learning techniques to maximize their scientific return. This study explores the use of Self-Organizing Maps (SOMs) to estimate galaxy parameters with a focus on handling cases of missing data and providing realistic probability distribution functions for the parameters. We train a SOM with a simulated mass-limited lightcone assuming a ugrizYJHKs+IRAC dataset, mimicking the Hyper Suprime-Cam (HSC) Deep joint dataset. For parameter estimation, we derive SOM likelihood surfaces considering photometric errors to derive total (statistical and systematic) uncertainties. We explore the effects of missing data including which bands are particular critical to the accuracy of the derived parameters. We demonstrate that the parameter recovery is significantly better when the missing bands are "filled-in" rather than if they are completely omitted. We propose a practical method for such recovery of missing data., Comment: 22 pages, 12 figures, 1 table, accepted for publication in The Astronomical Journal
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- 2024
38. Galaxy merger challenge: A comparison study between machine learning-based detection methods
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Margalef-Bentabol, B., Wang, L., La Marca, A., Blanco-Prieto, C., Chudy, D., Domínguez-Sánchez, H., Goulding, A. D., Guzmán-Ortega, A., Huertas-Company, M., Martin, G., Pearson, W. J., Rodriguez-Gomez, V., Walmsley, M., Bickley, R. W., Bottrell, C., Conselice, C., and O'Ryan, D.
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Astrophysics - Astrophysics of Galaxies - Abstract
Various galaxy merger detection methods have been applied to diverse datasets. However, it is difficult to understand how they compare. We aim to benchmark the relative performance of machine learning (ML) merger detection methods. We explore six leading ML methods using three main datasets. The first one (the training data) consists of mock observations from the IllustrisTNG simulations and allows us to quantify the performance metrics of the detection methods. The second one consists of mock observations from the Horizon-AGN simulations, introduced to evaluate the performance of classifiers trained on different, but comparable data. The third one consists of real observations from the Hyper Suprime-Cam Subaru Strategic Program (HSC-SSP) survey. For the binary classification task (mergers vs. non-mergers), all methods perform reasonably well in the domain of the training data. At $0.1
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- 2024
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39. Urban mapping in Dar es Salaam using AJIVE
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Carrington, Rachel J., Dryden, Ian L., Ellis, Madeleine, Goulding, James O., Preston, Simon P., and Sirl, David J.
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Statistics - Applications - Abstract
Mapping deprivation in urban areas is important, for example for identifying areas of greatest need and planning interventions. Traditional ways of obtaining deprivation estimates are based on either census or household survey data, which in many areas is unavailable or difficult to collect. However, there has been a huge rise in the amount of new, non-traditional forms of data, such as satellite imagery and cell-phone call-record data, which may contain information useful for identifying deprivation. We use Angle-Based Joint and Individual Variation Explained (AJIVE) to jointly model satellite imagery data, cell-phone data, and survey data for the city of Dar es Salaam, Tanzania. We first identify interpretable low-dimensional structure from the imagery and cell-phone data, and find that we can use these to identify deprivation. We then consider what is gained from further incorporating the more traditional and costly survey data. We also introduce a scalar measure of deprivation as a response variable to be predicted, and consider various approaches to multiview regression, including using AJIVE scores as predictors., Comment: 34 pages, 25 figures
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- 2024
40. RUBIES: JWST/NIRSpec Confirmation of an Infrared-luminous, Broad-line Little Red Dot with an Ionized Outflow
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Wang, Bingjie, de Graaff, Anna, Davies, Rebecca L., Greene, Jenny E., Leja, Joel, Brammer, Gabriel B., Goulding, Andy D., Miller, Tim B., Suess, Katherine A., Weibel, Andrea, Williams, Christina C., Bezanson, Rachel, Boogaard, Leindert A., Cleri, Nikko J., Hirschmann, Michaela, Katz, Harley, Labbe, Ivo, Maseda, Michael V., Matthee, Jorryt, McConachie, Ian, Naidu, Rohan P., Oesch, Pascal A., Rix, Hans-Walter, Setton, David J., and Whitaker, Katherine E.
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Astrophysics - Astrophysics of Galaxies - Abstract
The JWST discovery of ``little red dots'' (LRDs) is reshaping our picture of the early Universe, yet the physical mechanisms driving their compact size and UV-optical colors remain elusive. Here we report an unusually bright LRD ($z=3.1$) observed as part of the RUBIES program. This LRD exhibits broad emission lines (FWHM $\sim4000$km/s), a blue UV continuum, a clear Balmer break and a red continuum sampled out to rest 4 $\mu$m with MIRI. We develop a new joint galaxy and AGN model within the Prospector Bayesian inference framework and perform spectrophotometric modeling using NIRCam, MIRI, and NIRSpec/Prism observations. Our fiducial model reveals a $M_*\sim 10^9M_\odot$ galaxy alongside a dust-reddened AGN driving the optical emission. Explaining the rest-frame optical color as a reddened AGN requires $A_{\rm v}\gtrsim3$, suggesting that a great majority of the accretion disk energy is re-radiated as dust emission. Yet despite clear AGN signatures, we find a surprising lack of hot torus emission, which implies that either the dust emission in this object must be cold, or the red continuum must instead be driven by a massive, evolved stellar population of the host galaxy -- seemingly inconsistent with the high EW broad lines (H$\alpha$ EW $\sim800$\AA). The widths and luminosities of Pa$\beta$, Pa$\delta$, Pa$\gamma$, and H$\alpha$ imply a modest black hole mass of $M_{\rm BH}\sim10^8M_\odot$. Additionally, we identify a narrow blue-shifted HeI absorption in G395M spectra, signaling an ionized outflow with kinetic energy up to $\sim1$\% the luminosity of the AGN. The low redshift of RUBIES-BLAGN-1 combined with the depth and richness of the JWST imaging and spectroscopic observations provide a unique opportunity to build a physical model for these so-far mysterious LRDs, which may prove to be a crucial phase in the early formation of massive galaxies and their supermassive black holes., Comment: Fixed a typo that made Fig 4b corresponded to an incorrect plot. 22 pages, 9 figures, 4 tables
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- 2024
41. UNCOVER NIRSpec/PRISM Spectroscopy Unveils Evidence of Early Core Formation in a Massive, Centrally Dusty Quiescent Galaxy at $z_{spec}=3.97$
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Setton, David J., Khullar, Gourav, Miller, Tim B., Bezanson, Rachel, Greene, Jenny E., Suess, Katherine A., Whitaker, Katherine E., Antwi-Danso, Jacqueline, Atek, Hakim, Brammer, Gabriel, Cutler, Sam E., Dayal, Pratika, Feldmann, Robert, Furtak, Lukas J., Fujimoto, Seiji, Glazebrook, Karl, Goulding, Andy D., Kokorev, Vasily, Labbe, Ivo, Leja, Joel, Ma, Yilun, Marchesini, Danilo, Nanayakkara, Themiya, Pan, Richard, Price, Sedona H., Siegel, Jared C., Shipley, Heath, Weaver, John R., van Dokkum, Pieter, Wang, Bingjie, and Williams, Christina C.
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Astrophysics - Astrophysics of Galaxies - Abstract
We report the spectroscopic confirmation of a massive ($\log(M_\star/M_\odot)=10.34 \pm_{0.07}^{0.06}$), HST-dark ($m_\mathrm{F150W} - m_\mathrm{F444W} = 3.6$) quiescent galaxy at $z_{spec}=3.97$ in the UNCOVER survey. NIRSpec/PRISM spectroscopy and a non-detection in deep ALMA imaging surprisingly reveals that the galaxy is consistent with a low ($<$10 $M_\odot \ \mathrm{yr^{-1}}$) star formation rate despite evidence for moderate dust attenuation. The F444W image is well modeled with a two component \sersic fit that favors a compact, $r_e\sim200$ pc, $n\sim2.9$ component and a more extended, $r_e\sim1.6$ kpc, $n\sim1.7$ component. The galaxy exhibits strong color gradients: the inner regions are significantly redder than the outskirts. Spectral energy distribution models that reproduce both the red colors and low star formation rate in the center of UNCOVER 18407 require both significant ($A_v\sim1.4$ mag) dust attenuation and a stellar mass-weighted age of 900 Myr, implying 50\% of the stars in the core already formed by $z=7.5$. Using spatially resolved annular mass-to-light measurements enabled by the galaxy's moderate magnification ($\mu=2.12\pm_{0.01}^{0.05}$) to reconstruct a radial mass profile from the best-fitting two-component \sersic model, we infer a total mass-weighted $r_\mathrm{eff} = 0.72 \pm_{0.11}^{0.15}$ kpc and log$(\Sigma_\mathrm{1 kpc} \ [\mathrm{M_\odot/kpc^2}]) = 9.61 \pm_{0.10}^{0.08}$. The early formation of a dense, low star formation rate, and dusty core embedded in a less attenuated stellar envelope suggests an evolutionary link between the earliest-forming massive galaxies and their elliptical descendants. Furthermore, the disparity between the global, integrated dust properties and the spatially resolved gradients highlights the importance of accounting for radially varying stellar populations when characterizing the early growth of galaxy structure., Comment: 17 pages, 9 figures, 2 tables. Resubmitted to ApJ after response to referee and update to include new medium band imaging from the JWST MEGASCIENCE program. Comments welcome!
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- 2024
42. Spectroscopic Confirmation of Obscured AGN Populations from Unsupervised Machine Learning
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Hviding, Raphael E., Hainline, Kevin N., Goulding, Andy D., and Greene, Jenny E.
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Astrophysics - Astrophysics of Galaxies - Abstract
We present the result of a spectroscopic campaign targeting Active Galactic Nucleus (AGN) candidates selected using a novel unsupervised machine-learning (ML) algorithm trained on optical and mid-infrared (mid-IR) photometry. AGN candidates are chosen without incorporating prior AGN selection criteria and are fainter, redder, and more numerous, $\sim$340 AGN deg$^{-2}$, than comparable photometric and spectroscopic samples. In this work we obtain 178 rest-optical spectra from two candidate ML-identified AGN classes with the Hectospec spectrograph on the MMT Observatory. We find that our first ML-identified group, is dominated by Type I AGNs (85%) with a $<3$% contamination rate from non-AGNs. Our second ML-identified group is comprised mostly of Type II AGNs (65%) with a moderate contamination rate of 15% primarily from star-forming galaxies. Our spectroscopic analyses suggest that the classes recover more obscured AGNs, confirming that ML techniques are effective at recovering large populations of AGNs at high levels of extinction. We demonstrate the efficacy of pairing existing WISE data with large-area and deep optical/near-infrared photometric surveys to select large populations of AGNs and recover obscured SMBH growth. This approach is well suited to upcoming photometric surveys, such as Euclid, Rubin, and Roman., Comment: 23 pages, 16 figures. Accepted for publication in The Astronomical Journal
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- 2024
43. Celebration of Vivien Edwards’ biography of Mary Sutherland : Scion, 3 June 2021
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Goulding, Chris
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- 2021
44. The US Food and Drug Administration’s drug safety recommendations and long-acting beta2-agonist dispensing pattern changes in adult asthma patients: 2003–2012
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Zhou EH, Seymour S, Goulding MR, Kang EM, Major JM, and Iyasu S
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LABA ,dispensing pattern ,U.S. FDA ,regulatory activities ,Immunologic diseases. Allergy ,RC581-607 - Abstract
Esther H Zhou,1 Sally Seymour,2 Margie R Goulding,1 Elizabeth M Kang,1 Jacqueline M Major,1 Solomon Iyasu1 1Division of Epidemiology, Office of Surveillance and Epidemiology, 2Office of New Drugs, Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, MD, USA Background: Emerging safety issues associated with long-acting beta2-agonist (LABA) have led to multiple regulatory activities by the US Food and Drug Administration (FDA) since 2003, including Drug Safety Communications (DSCs) in 2010. These DSCs had three specific recommendations for the safe use of LABA products in adult asthma treatment. Methods: We examined the initiation of LABA-containing products for adult asthma treatment using an intermittent time series approach in a claims database from 2003 to 2012. We assessed the alignment of dispensing patterns with the following 2010 FDA recommendations: 1) contraindicated use of single-ingredient (SI)-LABA without an asthma controller medication (ACM); 2) a LABA should only be used when asthma is not adequately controlled on inhaled corticosteroids (ICSs) or ACM; and 3) step-down asthma therapy (e.g., discontinue LABA) when asthma control is achieved. Results: There were 477,922 adults (18–64 years old) dispensed a new LABA during 2003–2012. Among LABA initiators, patients who initiated an SI-LABA and who did “not” have an ACM dispensed on the same date decreased from >9% in 2003 (the initial labeling change) to
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- 2017
45. Exploring the Unexplored: Understanding the Impact of Layer Adjustments on Image Classification
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Liu, Haixia, Brailsford, Tim, Goulding, James, Smith, Gavin, and Bull, Larry
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Computer Science - Computer Vision and Pattern Recognition - Abstract
This paper investigates how adjustments to deep learning architectures impact model performance in image classification. Small-scale experiments generate initial insights although the trends observed are not consistent with the entire dataset. Filtering operations in the image processing pipeline are crucial, with image filtering before pre-processing yielding better results. The choice and order of layers as well as filter placement significantly impact model performance. This study provides valuable insights into optimizing deep learning models, with potential avenues for future research including collaborative platforms.
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- 2024
46. The HMXB Luminosity Functions of Dwarf Galaxies
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Geda, Robel, Goulding, Andy D., Lehmer, Bret D., Greene, Jenny E., and Kulkarni, Anish
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Astrophysics - Astrophysics of Galaxies ,Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Solar and Stellar Astrophysics - Abstract
Drawing from the Chandra archive and using a carefully selected set of nearby dwarf galaxies, we present a calibrated high-mass X-ray binary (HMXB) luminosity function in the low-mass galaxy regime and search for an already hinted at dependence on metallicity. Our study introduces a new sample of local dwarf galaxies (D < 12.5 Mpc and M* < 5 x 10^9 M_sun), expanding the specific star-formation rates (sSFR) and gas-phase metallicities probed in previous investigations. Our analysis of the observed X-ray luminosity function indicates a shallower power-law slope for the dwarf galaxy HMXB population. In our study, we focus on dwarf galaxies that are more representative in terms of sSFR compared to prior work. In this regime, the HMXB luminosity function exhibits significant stochastic sampling at high luminosities. This likely accounts for the pronounced scatter observed in the galaxy-integrated HMXB population's Lx/SFR versus metallicity for our galaxy sample. Our calibration is necessary to understand the AGN content of low mass galaxies identified in current and future X-ray survey fields and has implications for binary population synthesis models, as well as X-ray driven cosmic heating in the early universe., Comment: 19 pages, 7 figures
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- 2024
47. UNCOVERing the contribution of black holes to reionization in the JWST era
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Dayal, Pratika, Volonteri, Marta, Greene, Jenny E., Kokorev, Vasily, Goulding, Andy D., Williams, Christina C., Furtak, Lukas J., Zitrin, Adi, Atek, Hakim, Chemerynska, Iryna, Feldmann, Robert, Glazebrook, Karl, Labbe, Ivo, Nanayakkara, Themiya, Oesch, Pascal A., and Weaver, John R.
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Astrophysics - Astrophysics of Galaxies - Abstract
With its sensitivity in the rest-frame optical, the James Webb Space Telescope (JWST) has uncovered active galactic nuclei (AGN), comprising both intrinsically faint and heavily reddened sources, well into the first billion years of the Universe, at $z \sim 4-11$. In this work, we revisit the AGN contribution to reionization given the high number densities associated with these objects. We use the DELPHI semi-analytic model, base-lined against the latest high-redshift datasets from the JWST and the Atacama Large millimetre Array (ALMA) to model early star forming galaxies and AGN. We calculate the escape fractions of ionizing radiation from both star formation and AGN and include the impact of reionization feeback in suppressing the baryonic content of low-mass galaxies in ionized regions. This model is validated against the key observables for star forming galaxy, AGN and reionization. In our {\it fiducial} model, reionization reaches its mid-point at $z \sim 6.9$ and ends by $z \sim 5.9$. Low stellar mass ($M_*\leq 10^9M_\odot$) star forming galaxies are found to be the key drivers of the reionization process, providing about $77\%$ of the total photon budget. Despite their high numbers, high accretion rates and higher escape fractions compared to star forming galaxies at $z \sim 5$, AGN only provide about $23\%$ of the total reionization budget which is dominated by black holes in high stellar mass systems (with $M_* \geq 10^9M_\odot$). This is because AGN number densities become relevant only at $z \leq 7$ - as a result, AGN contribute as much as galaxies as late as $z \sim 6.2$, when reionization is already in its end stages. Finally, we find that even contrasting models of the AGN ionizing photon escape fraction (increasing or decreasing with stellar mass) do not qualitatively change our results., Comment: Submitted to A&A; comments welcome
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- 2024
48. Evidence for Intrinsic X-ray Weakness Among Red Quasars at Cosmic Noon
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Ma, Yilun, Goulding, Andy, Greene, Jenny E., Zakamska, Nadia L., Wylezalek, Dominika, and Jiang, Yan-Fei
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Astrophysics - Astrophysics of Galaxies - Abstract
Quasar feedback is a key ingredient in shaping galaxy evolution. A rare population of extremely red quasars (ERQs) at $z=2-3$ are often associated with high-velocity [O III]$\lambda5008$ outflows and may represent sites of strong feedback. In this paper, we present an X-ray study of 50 ERQs to investigate the link between the X-ray and outflow properties of these intriguing objects. Using hardness ratio analysis, we confirm that the ERQs are heavily obscured systems with gas column density reaching $N_\mathrm{H}=10^{23-24}\,\mathrm{cm^{-2}}$. We identify 20 X-ray-non-detected ERQs at high mid-infrared luminosities of $\nu L_\mathrm{\nu,6\mu m}\gtrsim3\times10^{46}\,\mathrm{erg\,s^{-1}}$. By stacking the X-ray observations, we find that the non-detected ERQs are on average underluminous in X-rays by a factor of $\sim10$ for their mid-infrared luminosities. We consider such X-ray weakness to be due to both heavy gas absorption and intrinsic factors. Moreover, we find that the X-ray-weak sources also display higher-velocity outflows. One option to explain this trend is that weaker X-rays facilitate more vigorous line-driven winds, which then accelerate the \oiii-emitting gas to kpc-scales. Alternatively, super-Eddington accretion could also lead to intrinsic X-ray weakness and more powerful continuum-driven outflow., Comment: 24 pages, 10 figures, Accepted to ApJ
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- 2024
49. Machine Vision-Enabled Sports Performance Analysis
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Aderinola, Timilehin B., Younesian, Hananeh, Goulding, Cathy, Whelan, Darragh, Caulfield, Brian, and Ifrim, Georgiana
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Computer Science - Computer Vision and Pattern Recognition - Abstract
$\textbf{Goal:}$ This study investigates the feasibility of monocular 2D markerless motion capture (MMC) using a single smartphone to measure jump height, velocity, flight time, contact time, and range of motion (ROM) during motor tasks. $\textbf{Methods:}$ Sixteen healthy adults performed three repetitions of selected tests while their body movements were recorded using force plates, optical motion capture (OMC), and a smartphone camera. MMC was then performed on the smartphone videos using OpenPose v1.7.0. $\textbf{Results:}$ MMC demonstrated excellent agreement with ground truth for jump height and velocity measurements. However, MMC's performance varied from poor to moderate for flight time, contact time, ROM, and angular velocity measurements. $\textbf{Conclusions:}$ These findings suggest that monocular 2D MMC may be a viable alternative to OMC or force plates for assessing sports performance during jumps and velocity-based tests. Additionally, MMC could provide valuable visual feedback for flight time, contact time, ROM, and angular velocity measurements.
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- 2023
50. JWST UNCOVER: The Overabundance of Ultraviolet-luminous Galaxies at $z>9$
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Chemerynska, Iryna, Atek, Hakim, Furtak, Lukas J., Zitrin, Adi, Greene, Jenny E., Dayal, Pratika, Weibel, Andrea, Fujimoto, Seiji, Kokorev, Vasily, Goulding, Andy D., Williams, Christina C., Nanayakkara, Themiya, Bezanson, Rachel, Brammer, Gabriel, Cutler, Sam E., Labbe, Ivo, Leja, Joel, Pan, Richard, Price, Sedona H., van Dokkum, Pieter, Wang, Bingjie, Weaver, John R., and Whitaker, Katherine E.
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Astrophysics - Astrophysics of Galaxies - Abstract
Over the past year, JWST has uncovered galaxies at record-breaking distances up to $z \sim 13$. The JWST UNCOVER (ultra-deep NIRSpec and NIRcam observations before the epoch of reionization) program has obtained ultra-deep multiwavelength NIRCam imaging of the massive galaxy cluster Abell 2744 over $\sim 45$ arcmin$^{2}$ down to $\sim 29.5$ AB mag. Here, we present a robust ultraviolet (UV) luminosity function derived through lensing clusters at $9
9$ in recent JWST studies. In particular, a double power-law (DPL) describes better the bright-end of the luminosity function compared to the classical Schechter form. The number density of these bright galaxies is 10-100 times larger than theoretical predictions and previous findings based on Hubble Space Telescope (HST) observations. Additionally, we measure a star formation rate density of $\rho_{\rm SFR} = 10^{-2.64}$ M$_{\odot}$~yr$^{-1}$~Mpc$^{-3}$ at these redshifts, which is 4 to 10 times higher than galaxy formation models that assume a constant star formation efficiency. Future wide-area surveys and accurate modeling of lensing-assisted observations will reliably constrain both the bright and the dim end of the UV luminosity function at $z>9$, which will provide key benchmarks for galaxy formation models., Comment: Published in MNRAS - Published
- 2023
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