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2. Prevalence of pulmonary embolism in patients with syncope

Author

Badertscher, Patrick, du Fay de Lavallaz, Jeanne, Hammerer-Lercher, Angelika, Nestelberger, Thomas, Zimmermann, Tobias, Geiger, Marc, Imahorn, O., Miró, Òscar, Salgado, Emilio, Christ, Michael, Cullen, Louise, Than, Martin, Martin-Sanchez, F. Javier, Di Somma, Salvatore, Peacock, W. Frank, Keller, Dagmar I., Costabel, Juan Pablo, Walter, Joan, Boeddinghaus, Jasper, Twerenbold, Raphael, Méndez, Adriana, Gospodinov, B., Puelacher, Christian, Wussler, Desiree, Koechlin, Luca, Kawecki, Damian, Geigy, Nicolas, Strebel, Ivo, Lohrmann, Jens, Kühne, Michael, Reichlin, Tobias, Mueller, Christian, Rubini Giménez, M., Kozhuharov, Nikola, Shrestha, Samyut, Sazgary, Lorraine, Morawiec, B., Muzyk, P., Nowalany-Kozielska, Ewa, Bustamante Mandrión, José, Poepping, Imke, Freese, Michael, Meissner, Kathrin, Kulangara, Caroline, Fuenzalida Inostroza, Carolina Isabel, Greenslade, Jaimi, Hawkins, Tracey, Rentsch, Katharina, von Eckardstein, Arnold, Buser, Andreas, Kloos, W., Steude, Jana, Osswald, Stefan, Badertscher, Patrick, du Fay de Lavallaz, Jeanne, Hammerer-Lercher, Angelika, Nestelberger, Thomas, Zimmermann, Tobias, Geiger, Marc, Imahorn, O., Miró, Òscar, Salgado, Emilio, Christ, Michael, Cullen, Louise, Than, Martin, Martin-Sanchez, F. Javier, Di Somma, Salvatore, Peacock, W. Frank, Keller, Dagmar I., Costabel, Juan Pablo, Walter, Joan, Boeddinghaus, Jasper, Twerenbold, Raphael, Méndez, Adriana, Gospodinov, B., Puelacher, Christian, Wussler, Desiree, Koechlin, Luca, Kawecki, Damian, Geigy, Nicolas, Strebel, Ivo, Lohrmann, Jens, Kühne, Michael, Reichlin, Tobias, Mueller, Christian, Rubini Giménez, M., Kozhuharov, Nikola, Shrestha, Samyut, Sazgary, Lorraine, Morawiec, B., Muzyk, P., Nowalany-Kozielska, Ewa, Bustamante Mandrión, José, Poepping, Imke, Freese, Michael, Meissner, Kathrin, Kulangara, Caroline, Fuenzalida Inostroza, Carolina Isabel, Greenslade, Jaimi, Hawkins, Tracey, Rentsch, Katharina, von Eckardstein, Arnold, Buser, Andreas, Kloos, W., Steude, Jana, and Osswald, Stefan

Abstract

Background: The prevalence of pulmonary embolism (PE) in patients presenting with syncope to the emergency department (ED) is largely unknown. This information, however, is necessary to balance the potential medical benefit or harm of systematic PE screening in patients presenting with syncope to the ED. Objectives: This study sought to determine the prevalence of PE in patients with syncope. Methods: Unselected patients presenting with syncope to the ED were prospectively enrolled in a diagnostic multicenter study. Pre-test clinical probability for PE was assessed using the 2-level Wells score and the results of D-dimer testing using age-adapted cutoffs. Presence of PE was evaluated by imaging modalities, when ordered as part of the clinical assessment by the treating ED physician or by long-term follow-up data. Results: Long-term follow-up was complete in 1,380 patients (99%) at 360 days and 1,156 patients (83%) at 720 days. Among 1,397 patients presenting with syncope to the ED, PE was detected at presentation in 19 patients (1.4%; 95% confidence interval [CI]: 0.87% to 2.11%). The incidence of new PEs or cardiovascular death during 2-year follow-up was 0.9% (95% CI: 0.5% to 1.5%). In the subgroup of patients hospitalized (47%), PE was detected at presentation in 15 patients (2.3%; 95% CI: 1.4% to 3.7%). The incidence of new PEs or cardiovascular death during 2-year follow-up was 0.9% (95% CI: 0.4% to 2.0%). Conclusions: PE seems to be a rather uncommon cause of syncope among patients presenting to the ED. Therefore, systematic PE-screening in all patients with syncope does not seem warranted. (BAsel Syncope EvaLuation Study [BASEL IX]; NCT01548352)

Published
2019

6. Temperature Tuning of Optical Properties of High Refractive Index Metal Oxide Films Obtained by the Sol-Gel Method.

Author

Babeva, T., Lazarova, K., Vasileva, M., Gospodinov, B., and Dikova, J.

Subjects
METALLIC oxides, OPTICAL properties of metallic films, SOL-gel processes, REFRACTIVE index measurement, X-ray diffraction, CURVE fitting
Abstract

The present study reports on the deposition and characterization of thin Ta2O5, TiO2 and Nb2O5 film, obtained by the sol-gel method using tantalum ethoxide, titanium isopropoxide and niobium chloride as precursors and specially developed water free sol-gel procedure. Structure and morphology of the films were inspected trough XRD and SEM measurements. Refractive index, extinction coefficient and thickness of the films were determined from reflectance spectra using non-linear curve fitting method. Refractive index values as high as 1.85, 2.07 and 2.17 were obtained for Ta2O5, TiO2 and Nb2O5 film, respectively at wavelength of 600 nm. The possibility of controlled tuning of optical properties by appropriate annealing was demonstrated and discussed. [ABSTRACT FROM AUTHOR]

Published
2013

9. Prevalence of Pulmonary Embolism in Patients With Syncope.

Author

Badertscher P, du Fay de Lavallaz J, Hammerer-Lercher A, Nestelberger T, Zimmermann T, Geiger M, Imahorn O, Miró Ò, Salgado E, Christ M, Cullen L, Than M, Martin-Sanchez FJ, Di Somma S, Peacock WF, Keller DI, Costabel JP, Walter J, Boeddinghaus J, Twerenbold R, Méndez A, Gospodinov B, Puelacher C, Wussler D, Koechlin L, Kawecki D, Geigy N, Strebel I, Lohrmann J, Kühne M, Reichlin T, and Mueller C

Subjects
Adult, Aged, Aged, 80 and over, Female, Global Health, Humans, Incidence, Male, Middle Aged, Prevalence, Prognosis, Prospective Studies, Pulmonary Embolism etiology, Risk Factors, Survival Rate trends, Emergency Service, Hospital statistics & numerical data, Pulmonary Embolism epidemiology, Syncope complications
Abstract

Background: The prevalence of pulmonary embolism (PE) in patients presenting with syncope to the emergency department (ED) is largely unknown. This information, however, is necessary to balance the potential medical benefit or harm of systematic PE screening in patients presenting with syncope to the ED., Objectives: This study sought to determine the prevalence of PE in patients with syncope., Methods: Unselected patients presenting with syncope to the ED were prospectively enrolled in a diagnostic multicenter study. Pre-test clinical probability for PE was assessed using the 2-level Wells score and the results of D-dimer testing using age-adapted cutoffs. Presence of PE was evaluated by imaging modalities, when ordered as part of the clinical assessment by the treating ED physician or by long-term follow-up data., Results: Long-term follow-up was complete in 1,380 patients (99%) at 360 days and 1,156 patients (83%) at 720 days. Among 1,397 patients presenting with syncope to the ED, PE was detected at presentation in 19 patients (1.4%; 95% confidence interval [CI]: 0.87% to 2.11%). The incidence of new PEs or cardiovascular death during 2-year follow-up was 0.9% (95% CI: 0.5% to 1.5%). In the subgroup of patients hospitalized (47%), PE was detected at presentation in 15 patients (2.3%; 95% CI: 1.4% to 3.7%). The incidence of new PEs or cardiovascular death during 2-year follow-up was 0.9% (95% CI: 0.4% to 2.0%)., Conclusions: PE seems to be a rather uncommon cause of syncope among patients presenting to the ED. Therefore, systematic PE-screening in all patients with syncope does not seem warranted. (BAsel Syncope EvaLuation Study [BASEL IX]; NCT01548352)., (Copyright © 2019. Published by Elsevier Inc.)

Published
2019
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13. [On extracardial by-pass in cardiac valve stenoses].

Author

POPPOV G, STOIKOV M, GOSPODINOV B, SEDLOEV S, WOLTSCHANOVA S, IWANOV, and KOLEV I

Subjects
Constriction, Pathologic, Humans, Cardiac Surgical Procedures, Heart Valve Diseases, Heart Valves, Mitral Valve Stenosis, Thoracic Surgery
Published
1960

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