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926 results on '"Gopinath, Bamini"'

4. Genome-wide analysis identifies genetic effects on reproductive success and ongoing natural selection at the FADS locus

Author

Mathieson, Iain, Day, Felix R., Barban, Nicola, Tropf, Felix C., Brazel, David M., Vaez, Ahmad, van Zuydam, Natalie, Bitarello, Bárbara D., Gardner, Eugene J., Akimova, Evelina T., Azad, Ajuna, Bergmann, Sven, Bielak, Lawrence F., Boomsma, Dorret I., Bosak, Kristina, Brumat, Marco, Buring, Julie E., Cesarini, David, Chasman, Daniel I., Chavarro, Jorge E., Cocca, Massimiliano, Concas, Maria Pina, Davey Smith, George, Davies, Gail, Deary, Ian J., Esko, Tõnu, Faul, Jessica D., Franco, Oscar, Ganna, Andrea, Gaskins, Audrey J., Gelemanovic, Andrea, de Geus, Eco J. C., Gieger, Christian, Girotto, Giorgia, Gopinath, Bamini, Grabe, Hans Jörgen, Gunderson, Erica P., Hayward, Caroline, He, Chunyan, van Heemst, Diana, Hill, W. David, Hoffmann, Eva R., Homuth, Georg, Hottenga, Jouke Jan, Huang, Hongyang, Hyppӧnen, Elina, Ikram, M. Arfan, Jansen, Rick, Johannesson, Magnus, Kamali, Zoha, Kardia, Sharon L. R., Kavousi, Maryam, Kifley, Annette, Kiiskinen, Tuomo, Kraft, Peter, Kühnel, Brigitte, Langenberg, Claudia, Liew, Gerald, Lind, Penelope A., Luan, Jian’an, Mägi, Reedik, Magnusson, Patrik K. E., Mahajan, Anubha, Martin, Nicholas G., Mbarek, Hamdi, McCarthy, Mark I., McMahon, George, Medland, Sarah E., Meitinger, Thomas, Metspalu, Andres, Mihailov, Evelin, Milani, Lili, Missmer, Stacey A., Mitchell, Paul, Møllegaard, Stine, Mook-Kanamori, Dennis O., Morgan, Anna, van der Most, Peter J., de Mutsert, Renée, Nauck, Matthias, Nolte, Ilja M., Noordam, Raymond, Penninx, Brenda W. J. H., Peters, Annette, Peyser, Patricia A., Polašek, Ozren, Power, Chris, Pribisalic, Ajka, Redmond, Paul, Rich-Edwards, Janet W., Ridker, Paul M., Rietveld, Cornelius A., Ring, Susan M., Rose, Lynda M., Rueedi, Rico, Shukla, Vallari, Smith, Jennifer A., Stankovic, Stasa, Stefánsson, Kári, Stöckl, Doris, Strauch, Konstantin, Swertz, Morris A., Teumer, Alexander, Thorleifsson, Gudmar, Thorsteinsdottir, Unnur, Thurik, A. Roy, Timpson, Nicholas J., Turman, Constance, Uitterlinden, André G., Waldenberger, Melanie, Wareham, Nicholas J., Weir, David R., Willemsen, Gonneke, Zhao, Jing Hau, Zhao, Wei, Zhao, Yajie, Snieder, Harold, den Hoed, Marcel, Ong, Ken K., Mills, Melinda C., and Perry, John R. B.

Published
2023
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14. The Association between Dietary Intakes of Vitamins and Minerals with Tinnitus.

Author

Tang, Diana, Shekhawat, Giriraj S., Burlutsky, George, Mitchell, Paul, and Gopinath, Bamini

Abstract

Background: Tinnitus is the phantom perception of sound in the ears or head which may result from inflammation of the auditory pathway. A healthy diet consisting of a range of vitamins and minerals may be protective against tinnitus. This study aims to determine the association between intakes of dietary vitamins and minerals and the prevalence and incidence of tinnitus over 10 years. Methods: In this longitudinal cohort study of 2947 participants (aged ≥ 50 years), 935 (32%) cases of tinnitus were identified and included in prevalence analyses. The remaining 2012 participants were followed to establish 10-year incidence of tinnitus. A validated semi-quantitative food frequency questionnaire was used to determine intakes of dietary vitamins and minerals. Results: No significant associations with tinnitus prevalence were found. However, iron and zinc were significantly associated with incident tinnitus. There was a 44% (multivariate-adjusted HR: 1.44, 95% CI: 1.07–1.93) increased risk of developing incident tinnitus over 10 years with lower zinc intakes and a 35% increased risk with lower iron intakes (multivariate-adjusted HR: 1.35, 95% CI: 1.00–1.80). Conclusion: Higher intakes of zinc and iron were significantly associated with lower tinnitus risk. Due to a lack of comparable high-quality data, future research studies should include robust study designs. [ABSTRACT FROM AUTHOR]

Published
2024
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18. A deep-learning system for the assessment of cardiovascular disease risk via the measurement of retinal-vessel calibre

Author

Cheung, Carol Y., Xu, Dejiang, Cheng, Ching-Yu, Sabanayagam, Charumathi, Tham, Yih-Chung, Yu, Marco, Rim, Tyler Hyungtaek, Chai, Chew Yian, Gopinath, Bamini, Mitchell, Paul, Poulton, Richie, Moffitt, Terrie E., Caspi, Avshalom, Yam, Jason C., Tham, Clement C., Jonas, Jost B., Wang, Ya Xing, Song, Su Jeong, Burrell, Louise M., Farouque, Omar, Li, Ling Jun, Tan, Gavin, Ting, Daniel S. W., Hsu, Wynne, Lee, Mong Li, and Wong, Tien Y.

Published
2021
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21. Referral for disease-related visual impairment using retinal photograph-based deep learning: a proof-of-concept, model development study

Author

Tham, Yih-Chung, Anees, Ayesha, Zhang, Liang, Goh, Jocelyn Hui Lin, Rim, Tyler Hyungtaek, Nusinovici, Simon, Hamzah, Haslina, Chee, Miao-Li, Tjio, Gabriel, Li, Shaohua, Xu, Xinxing, Goh, Rick, Tang, Fangyao, Cheung, Carol Yim-Lui, Wang, Ya Xing, Nangia, Vinay, Jonas, Jost B, Gopinath, Bamini, Mitchell, Paul, Husain, Rahat, Lamoureux, Ecosse, Sabanayagam, Charumathi, Wang, Jie Jin, Aung, Tin, Liu, Yong, Wong, Tien Yin, and Cheng, Ching-Yu

Published
2021
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22. The Australian Eye and Ear Health Survey (AEEHS): Study protocol for a population-based cross-sectional study.

Author

Kha, Richard, Macken, Oonagh, Mitchell, Paul, Liew, Gerald, Keay, Lisa, Waddell, Colina, Yang, Eleanor, Do, Vu, Fricke, Tim, Newall, John, and Gopinath, Bamini

Subjects
INDIGENOUS Australians, VISUAL acuity, VISUAL fields, VISION disorders, HEARING disorders, RESEARCH protocols, HEALTH surveys
Abstract

Introduction: Vision and hearing impairments are highly prevalent and have a significant impact on physical, psychological and social wellbeing. There is a need for accurate, contemporary national data on the prevalence, risk factors and impacts of vision and hearing loss in Australian adults. Objectives: The Australian Eye and Ear Health Survey (AEEHS) aims to determine the prevalence, risk factors and impacts of vision and hearing loss in both Aboriginal and Torres Strait Islander and non-Indigenous older adults. Methods and analysis: The AEEHS is a population-based cross-sectional survey which will include 5,000 participants (3250 non-Indigenous aged 50 years or older and 1750 Aboriginal and Torres Strait Islander people aged 40 years or older) from 30 sites covering urban and rural/regional geographic areas, selected using a multi-stage, random cluster sampling strategy. Questionnaires will be administered to collect data on socio-demographic, medical, ocular and ontological history. The testing battery includes assessment of blood pressure, blood sugar, anthropometry, visual acuity (presenting, unaided, pinhole and best-corrected), refraction, tonometry, slit lamp and dilated eye examination, ocular imaging including optical coherence tomography (OCT), OCT-angiography and retinal photography, and automated visual fields. Audiometry, tympanometry and video otoscopy will also be performed. The primary outcomes are age-standardised prevalence of cause-specific vision and hearing impairment. Secondary outcomes are prevalence of non-blinding eye diseases (including dry eye disease), patterns in health service utilisation, universal health coverage metrics, risk factors for vision and hearing impairment, and impact on quality of life. [ABSTRACT FROM AUTHOR]

Published
2024
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23. Understanding barriers and enablers to participation in a proposed online lifestyle intervention for older adults with age-related macular degeneration to guide programme implementation.

Author

Kha, Richard, Wen, Qingyun, Bender, Nicholas, Jones, Charlotte, Gopinath, Bamini, Macniven, Rona, and Tang, Diana

Subjects
RETINAL degeneration treatment, LIFESTYLES, HEALTH literacy, HOLISTIC medicine, BEHAVIOR modification, QUALITATIVE research, VISION disorders, HUMAN services programs, RESEARCH funding, MEDICAL care, RETINAL degeneration, INTERVIEWING, INTERNET, LONELINESS, LEARNING, THEMATIC analysis, MOTIVATION (Psychology), AGING, HEALTH behavior, TECHNOLOGY, SOCIAL skills, GROUNDED theory, PATIENT participation, MENTAL depression, SOCIALIZATION, TIME, PHYSICAL mobility, PATIENTS' attitudes, OLD age
Abstract

Age-related macular degeneration (AMD) is a blinding condition associated with depression, loneliness and unhealthy lifestyle behaviours which drives AMD progression. We have proposed the first online lifestyle intervention for AMD, called Movement, Interaction and Nutrition for Greater Lifestyles in the Elderly (MINGLE) to promote positive lifestyle changes and reduce loneliness. This qualitative grounded-theory study explored enablers and barriers to future participation in MINGLE for older adults with AMD. Thirty-one participants were interviewed and thematic analysis revealed nine themes. Enablers to participation were: socialising and learning about AMD, motivation to improve health, programme accessibility and structure. Barriers were: lack of time, technology, limited knowledge regarding holistic interventions, vision-related issues, mobility and negative perception of group interactions. These factors must be considered when developing lifestyle interventions for AMD patients to maximise participation. Supporting technology use and raising awareness about benefits of healthy lifestyle behaviours for AMD may help overcome these barriers. [ABSTRACT FROM AUTHOR]

Published
2024
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43. A protocol for the Hearing impairment in Adults: A Longitudinal Outcomes Study (HALOS)

Author

Tang, Diana, primary, Tran, Yvonne, additional, McMahon, Catherine, additional, Turner, Jessica, additional, Amin, Janaki, additional, Sinha, Kompal, additional, Alam, Mohammad Nure, additional, Wuthrich, Viviana, additional, Sherman, Kerry A., additional, Garcia, Patrick, additional, Mitchell, Rebecca, additional, Braithwaite, Jeffrey, additional, Leigh, Greg, additional, Lim, Shermin, additional, Shekhawat, Giriraj Singh, additional, Rapport, Frances, additional, Ferguson, Melanie, additional, and Gopinath, Bamini, additional

Published
2023
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45. COVID-19 and tinnitus: an initiative to improve tinnitus care.

Author

Mui, Boaz, Leong, Natalie, Keil, Brenton, Domingo, Deepti, Dafny, Hila A., Manchaiah, Vinaya, Gopinath, Bamini, Muzaffar, Jameel, Chen, Jinsong, Bidargaddi, Niranjan, Timmer, Barbra H. B., Vitkovic, Jessica, Esterman, Adrian, and Shekhawat, Giriraj Singh

Subjects
TINNITUS, COMPUTER software, STATISTICS, COVID-19, IMMUNIZATION, HEALTH services accessibility, RESEARCH methodology, CROSS-sectional method, INTERNET, QUARANTINE, PATIENTS' attitudes, SOCIAL isolation, SELF-consciousness (Awareness), SURVEYS, DESCRIPTIVE statistics, GOVERNMENT policy, CHI-squared test, HEALTH, INFORMATION resources, RESEARCH funding, QUESTIONNAIRES, PATIENT care, SOCIAL skills, EMOTIONS, DATA analysis software, DATA analysis, LOGISTIC regression analysis, THEMATIC analysis, COVID-19 pandemic
Abstract

To investigate the effects of COVID-19 on individuals with tinnitus and their views to guide future tinnitus care. A mixed-methods cross-sectional research design. An online survey was completed by 365 individuals with tinnitus from Australia and other countries. Tinnitus was reported to be more bothersome during the pandemic by 36% of respondents, whereas 59% reported no change and 5% reported less bothersome tinnitus. Nearly half of the respondents had received COVID-19 vaccination(s) and 12% of them reported more bothersome tinnitus while 2% developed tinnitus post-vaccination. Australian respondents spent less time in self-isolation or quarantine and saw fewer change in in-person social contact than respondents from other countries. More than 70% of respondents thought that tinnitus care services were insufficient both before and during the pandemic. Regarding their opinions on how to improve tinnitus care in the future, five themes including alleviation of condition, government policies, reduced barriers, self- and public-awareness, and hearing devices were identified. A majority of respondents did not perceive any change in tinnitus perception and one-third of respondents had worsened tinnitus during the pandemic. To improve tinnitus care, better awareness and more accessible resources and management are crucial. [ABSTRACT FROM AUTHOR]

Published
2023
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50. Using a decision tree approach to determine hearing aid ownership in older adults.

Author

Tran, Yvonne, Tang, Diana, McMahon, Catherine, Mitchell, Paul, and Gopinath, Bamini

Subjects
TREATMENT of hearing disorders, DECISION trees, AUDITORY perception testing, STATISTICS, CONFIDENCE intervals, HEARING aids, MACHINE learning, T-test (Statistics), COMPARATIVE studies, AUDIOMETRY, RESEARCH funding, DESCRIPTIVE statistics, CHI-squared test, PREDICTION models, DATA analysis software, LOGISTIC regression analysis, ODDS ratio, SENSITIVITY & specificity (Statistics), ALGORITHMS, OLD age
Abstract

The main clinical intervention for older adults with hearing loss is the provision of hearing aids. However, uptake and usage in this population have historically been reported as low. The aim of this study was to understand the hearing loss characteristics, from measured audiometric hearing loss and self-perceived hearing handicap, that contribute to the decision of hearing aid ownership. A total of 2833 adults aged 50+ years, of which 329 reported hearing aid ownership, were involved with a population-based survey with audiometric hearing assessments. Classification and regression tree (CART) analysis was used to classify hearing aid ownership from audiometric measurements and hearing disability outcomes. An overall accuracy of 92.5% was found for the performance of the CART analysis in predicting hearing aid ownership from hearing loss characteristics. By including hearing disability, sensitivity for predicting hearing aid ownership increased by up to 40% compared with just audiometric hearing loss measurements alone. A decision tree approach that considers both objectively measured hearing loss and self-perceived hearing disability, could facilitate a more tailored and personalised approach for determining hearing aid needs in the older population. Without intervention, older adults with hearing loss are at higher risk of cognitive decline and higher rates of depression, anxiety, social isolation. The provision of hearing aids can compensate hearing function, however, uptake and usage have been reported as low. Using a more precise cut-off from audiometric measures and self-perceived hearing disability scores could facilitate a tailored and personalised approach to screen and identify older adults for hearing aid needs. [ABSTRACT FROM AUTHOR]

Published
2023
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