1. Use of Atypical Antipsychotic Agents in Bipolar and Schizoaffective Disorders
- Author
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Goodwin Fk and Ghaemi Sn
- Subjects
Olanzapine ,medicine.medical_specialty ,Bipolar Disorder ,medicine.drug_class ,medicine.medical_treatment ,Atypical antipsychotic ,medicine ,Humans ,Pharmacology (medical) ,Bipolar disorder ,Antipsychotic ,Psychiatry ,Clozapine ,Psychiatric Status Rating Scales ,Clinical Trials as Topic ,Risperidone ,medicine.disease ,Psychiatry and Mental health ,Treatment Outcome ,Psychotic Disorders ,Adjunctive treatment ,Drug Therapy, Combination ,medicine.symptom ,Psychology ,Mania ,Antipsychotic Agents ,medicine.drug - Abstract
Atypical antipsychotic agents seem to be effective treatments for bipolar disorder, especially as adjunctive treatments. They may be a safer and more effective alternative to the common practice of maintenance adjunctive treatment with traditional antipsychotic agents in patients with bipolar disorder. However, currently available research studies are limited methodologically mainly to open-label, uncontrolled designs. Further research is required before the definitive efficacy of these agents in bipolar disorder is established. If randomized or double-blind data support the open-label data reviewed here, atypical antipsychotic agents may possess an important role in the adjunctive treatment of bipolar disorder.
- Published
- 1999
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