937 results on '"Goodnow, Christopher C."'
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2. Autoantibodies against type I IFNs in humans with alternative NF-κB pathway deficiency
3. Broadly neutralizing SARS-CoV-2 antibodies through epitope-based selection from convalescent patients
4. Structural and functional characterization of capsid binding by anti-AAV9 monoclonal antibodies from infants after SMA gene therapy
5. Platform for isolation and characterization of SARS-CoV-2 variants enables rapid characterization of Omicron in Australia
6. STAT3 gain-of-function mutations connect leukemia with autoimmune disease by pathological NKG2Dhi CD8+ T cell dysregulation and accumulation
7. SAMD9L autoinflammatory or ataxia pancytopenia disease mutations activate cell-autonomous translational repression
8. Activation of the viral sensor oligoadenylate synthetase 2 (Oas2) prevents pregnancy-driven mammary cancer metastases
9. DOCK2 Deficiency Causes Defects in Antiviral T-Cell Responses and Impaired Control of Herpes Simplex Virus Infection.
10. Helper T cell immunity in humans with inherited CD4 deficiency
11. Expanded T cell clones with lymphoma driver somatic mutations in refractory celiac disease
12. Conformational diversity facilitates antibody mutation trajectories and discrimination between foreign and self-antigens
13. NINJ1 mediates plasma membrane rupture during lytic cell death
14. A Novel Heterozygous Variant in AICDA Impairs Ig Class Switching and Somatic Hypermutation in Human B Cells and is Associated with Autosomal Dominant HIGM2 Syndrome
15. Self-reactive B cells traverse a perfect storm of somatic mutagenesis to cause a virus-induced autoimmune disease
16. Isolation and characterisation of PR3-specific B cells and their immunoglobulin sequences
17. CD45-mediated control of TCR tuning in naïve and memory CD8+ T cells
18. Antigen-driven EGR2 expression is required for exhausted CD8+ T cell stability and maintenance
19. Deletion of self-reactive CCR7– thymocytes in the absence of MHC expression on thymic epithelial cells
20. Germinal center antibody mutation trajectories are determined by rapid self/foreign discrimination
21. Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity
22. Systems-guided forward genetic screen reveals a critical role of the replication stress response protein ETAA1 in T cell clonal expansion
23. DOCK2-deficiency causes defects in anti-viral T cell responses and poor control of herpes simplex virus infection
24. The actin regulator coronin 1A is mutant in a thymic egress–deficient mouse strain and in a patient with severe combined immunodeficiency
25. Role of Syk in B-Cell Development and Antigen-Receptor Signaling
26. Dependence of Germinal Center B Cells on Expression of CD21/CD35 for Survival
27. Intravenous Injection of Soluble Antigen Induces Thymic and Peripheral T-Cell Apoptosis
28. Balancing Immunity and Tolerance: Deleting and Tuning Lymphocyte Repertoires
29. Entry of B Cell Receptor into Signaling Domains Is Inhibited in Tolerant B Cells
30. Spontaneous Follicular Exclusion of SHP1-deficient B Cells Is Conditional on the Presence of Competitor Wild-type B Cells
31. Sequencing and Affinity Determination of Antigen-Specific B Lymphocytes from Peripheral Blood
32. High-throughput targeted long-read single cell sequencing reveals the clonal and transcriptional landscape of lymphocytes
33. Impaired thymic AIRE expression underlies autoantibodies against type I IFNs in humans with inborn errors of the alternative NF-kB pathway
34. Comparison of predicted and actual consequences of missense mutations
35. Discriminating Microbe from Self Suffers a Double Toll
36. Broadly neutralizing SARS-CoV-2 antibodies through epitope-based selection from convalescent patients
37. STAT5B restrains human B-cell differentiation to maintain humoral immune homeostasis
38. Autosomal-dominant B-cell deficiency with alopecia due to a mutation in NFKB2 that results in nonprocessable p100
39. Redemption of autoantibodies on anergic B cells by variable-region glycosylation and mutation away from self-reactivity
40. Zinc-finger protein ZFP318 is essential for expression of IgD, the alternatively spliced Igh product made by mature B lymphocytes
41. Ndfip1 mediates peripheral tolerance to self and exogenous antigen by inducing cell cycle exit in responding CD4 + T cells
42. Tolerance Mechanisms in the Late Phase of the Antibody Response
43. A DOCK8-WIP-WASp complex links T cell receptors to the actin cytoskeleton
44. Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation
45. Human T-bet governs the generation of a distinct subset of CD11c high CD21 low B cells
46. SATB1 ensures appropriate transcriptional programs within naïve CD8 + T cells
47. Genetic and structural basis of the human anti-α-galactosyl antibody response
48. Abstract 665: Correlation between a CTLA-4 single nucleotide polymorphism and high response to anti-PD1/PDL1 immunotherapy in advanced non small cell lung cancer
49. DOCK8 is critical for the survival and function of NKT cells
50. C3d of Complement as a Molecular Adjuvant: Bridging Innate and Acquired Immunity
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