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1,187 results on '"Goodman, Wayne K."'

1. Disruption of neural periodicity predicts clinical response after deep brain stimulation for obsessive-compulsive disorder

Author

Provenza, Nicole R., Reddy, Sandesh, Allam, Anthony K., Rajesh, Sameer V., Diab, Nabeel, Reyes, Gabriel, Caston, Rose M., Katlowitz, Kalman A., Gandhi, Ajay D., Bechtold, Raphael A., Dang, Huy Q., Najera, Ricardo A., Giridharan, Nisha, Kabotyanski, Katherine E., Momin, Faiza, Hasen, Mohammed, Banks, Garrett P., Mickey, Brian J., Kious, Brent M., Shofty, Ben, Hayden, Benjamin Y., Herron, Jeffrey A., Storch, Eric A., Patel, Ankit B., Goodman, Wayne K., and Sheth, Sameer A.

Published
2024
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7. Examining the Effectiveness of the Transdiagnostic Unified Protocol for Emotional Disorders Delivered to Youth Following Hurricane Harvey

Author

Goetz, Amy R., Kennedy, Sarah M., Kook, Minjee, Guzick, Andrew G., Nwankwo, Gifty N. Amos, Hana, Lynn M., Schneider, Sophie C., Cepeda, Sandra L., Weinzimmer, Saira A., Shah, Asim A., Goodman, Wayne K., Salloum, Alison, Ehrenreich-May, Jill, and Storch, Eric A.

Abstract

Background: Hurricane Harvey struck southeast Texas in August 2017 resulting in widespread destruction and significant emotional distress. Objective: We examined the effectiveness of a transdiagnostic psychotherapeutic intervention delivered to youth with emotional disorders in a large, community health system following this hurricane. Methods: One hundred forty-nine youth aged 5 to 17 years with a history of hurricane exposure and emotional difficulties received an average of 6.4 (SD = 3.4) psychotherapy sessions using the Unified Protocols for Transdiagnostic Treatment of Emotional Disorders in Children and Adolescents. Youth-caregiver dyads completed measures of disaster exposure and impact at baseline as well as anxiety and depression at baseline and each therapy session. Symptom severity and level of functioning were rated by the clinician. Latent growth curve modeling was used to examine symptom change over time. Results: Children and adolescents began treatment with moderate levels of anxiety and depressive symptoms, symptom severity, and difficulties in daily functioning. Anxiety and depressive symptoms and symptom severity declined significantly over the treatment period. Clinician ratings of functionality evidenced significant improvement over time. Older age was correlated with more depressive symptoms at baseline and superior functioning at baseline with fewer completed treatment sessions. Conclusion: In this naturalistic, community-based effectiveness study we found significant improvement on measures of anxiety, depression, symptom severity, and daily functioning. Findings suggest that a transdiagnostic intervention may be effective for addressing a range of emotional concerns in the aftermath of a natural disaster. These results can be used to inform and refine evidence-based interventions that improve the mental health and wellbeing of disaster-exposed youth.

Published
2023
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8. Beta activity in human anterior cingulate cortex mediates reward biases

Author

Xiao, Jiayang, Adkinson, Joshua A., Myers, John, Allawala, Anusha B., Mathura, Raissa K., Pirtle, Victoria, Najera, Ricardo, Provenza, Nicole R., Bartoli, Eleonora, Watrous, Andrew J., Oswalt, Denise, Gadot, Ron, Anand, Adrish, Shofty, Ben, Mathew, Sanjay J., Goodman, Wayne K., Pouratian, Nader, Pitkow, Xaq, Bijanki, Kelly R., Hayden, Benjamin, and Sheth, Sameer A.

Published
2024
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10. Future directions in psychiatric neurosurgery: Proceedings of the 2022 American Society for Stereotactic and Functional Neurosurgery meeting on surgical neuromodulation for psychiatric disorders

Author

Hitti, Frederick L, Widge, Alik S, Riva-Posse, Patricio, Malone, Donald A, Okun, Michael S, Shanechi, Maryam M, Foote, Kelly D, Lisanby, Sarah H, Ankudowich, Elizabeth, Chivukula, Srinivas, Chang, Edward F, Gunduz, Aysegul, Hamani, Clement, Feinsinger, Ashley, Kubu, Cynthia S, Chiong, Winston, Chandler, Jennifer A, Carbunaru, Rafael, Cheeran, Binith, Raike, Robert S, Davis, Rachel A, Halpern, Casey H, Vanegas-Arroyave, Nora, Markovic, Dejan, Bick, Sarah K, McIntyre, Cameron C, Richardson, R Mark, Dougherty, Darin D, Kopell, Brian H, Sweet, Jennifer A, Goodman, Wayne K, Sheth, Sameer A, and Pouratian, Nader

Subjects
Biomedical and Clinical Sciences, Rehabilitation, Neurosciences, Brain Disorders, Good Health and Well Being, Humans, United States, Neurosurgery, Deep Brain Stimulation, Neurosurgical Procedures, Mental Disorders, Psychosurgery, Deep brain stimulation, Treatment resistant depression, Obsessive compulsive disorder, Tourette syndrome, Neuromodulation, Medical and Health Sciences, Neurology & Neurosurgery, Biomedical and clinical sciences, Health sciences
Abstract

ObjectiveDespite advances in the treatment of psychiatric diseases, currently available therapies do not provide sufficient and durable relief for as many as 30-40% of patients. Neuromodulation, including deep brain stimulation (DBS), has emerged as a potential therapy for persistent disabling disease, however it has not yet gained widespread adoption. In 2016, the American Society for Stereotactic and Functional Neurosurgery (ASSFN) convened a meeting with leaders in the field to discuss a roadmap for the path forward. A follow-up meeting in 2022 aimed to review the current state of the field and to identify critical barriers and milestones for progress.DesignThe ASSFN convened a meeting on June 3, 2022 in Atlanta, Georgia and included leaders from the fields of neurology, neurosurgery, and psychiatry along with colleagues from industry, government, ethics, and law. The goal was to review the current state of the field, assess for advances or setbacks in the interim six years, and suggest a future path forward. The participants focused on five areas of interest: interdisciplinary engagement, regulatory pathways and trial design, disease biomarkers, ethics of psychiatric surgery, and resource allocation/prioritization. The proceedings are summarized here.ConclusionThe field of surgical psychiatry has made significant progress since our last expert meeting. Although weakness and threats to the development of novel surgical therapies exist, the identified strengths and opportunities promise to move the field through methodically rigorous and biologically-based approaches. The experts agree that ethics, law, patient engagement, and multidisciplinary teams will be critical to any potential growth in this area.

Published
2023

13. Proceedings of the 10th annual deep brain stimulation think tank: Advances in cutting edge technologies, artificial intelligence, neuromodulation, neuroethics, interventional psychiatry, and women in neuromodulation

Author

Wong, Joshua K, Mayberg, Helen S, Wang, Doris D, Richardson, R Mark, Halpern, Casey H, Krinke, Lothar, Arlotti, Mattia, Rossi, Lorenzo, Priori, Alberto, Marceglia, Sara, Gilron, Ro’ee, Cavanagh, James F, Judy, Jack W, Miocinovic, Svjetlana, Devergnas, Annaelle D, Sillitoe, Roy V, Cernera, Stephanie, Oehrn, Carina R, Gunduz, Aysegul, Goodman, Wayne K, Petersen, Erika A, Bronte-Stewart, Helen, Raike, Robert S, Malekmohammadi, Mahsa, Greene, David, Heiden, Petra, Tan, Huiling, Volkmann, Jens, Voon, Valerie, Li, Luming, Sah, Pankaj, Coyne, Terry, Silburn, Peter A, Kubu, Cynthia S, Wexler, Anna, Chandler, Jennifer, Provenza, Nicole R, Heilbronner, Sarah R, San Luciano, Marta, Rozell, Christopher J, Fox, Michael D, de Hemptinne, Coralie, Henderson, Jaimie M, Sheth, Sameer A, and Okun, Michael S

Subjects
Biological Psychology, Biomedical and Clinical Sciences, Psychology, Bioengineering, Neurosciences, Assistive Technology, Depression, Rehabilitation, Mental Health, Mental health, deep brain stimulation, artificial intelligence, neuroethics, Parkinson's disease, dystonia, interventional psychiatry, adaptive DBS, epilepsy, Parkinson’s disease, Cognitive Sciences, Experimental Psychology, Biological psychology, Cognitive and computational psychology
Abstract

The deep brain stimulation (DBS) Think Tank X was held on August 17-19, 2022 in Orlando FL. The session organizers and moderators were all women with the theme women in neuromodulation. Dr. Helen Mayberg from Mt. Sinai, NY was the keynote speaker. She discussed milestones and her experiences in developing depression DBS. The DBS Think Tank was founded in 2012 and provides an open platform where clinicians, engineers and researchers (from industry and academia) can freely discuss current and emerging DBS technologies as well as the logistical and ethical issues facing the field. The consensus among the DBS Think Tank X speakers was that DBS has continued to expand in scope however several indications have reached the "trough of disillusionment." DBS for depression was considered as "re-emerging" and approaching a slope of enlightenment. DBS for depression will soon re-enter clinical trials. The group estimated that globally more than 244,000 DBS devices have been implanted for neurological and neuropsychiatric disorders. This year's meeting was focused on advances in the following areas: neuromodulation in Europe, Asia, and Australia; cutting-edge technologies, closed loop DBS, DBS tele-health, neuroethics, lesion therapy, interventional psychiatry, and adaptive DBS.

Published
2023

15. Measurement invariance of the Screen for Child Anxiety Related Emotional Disorders (SCARED) across ethnicity, age, and sex among youth with depression

Author

Silva, Ticiane, Spencer, Samuel D., Higham, Miranda, Castillo, Ace A., Minhajuddin, Abu, Gorman, April, Goodman, Lynnel C., Pinciotti, Caitlin M., Hernandez, Stephanie, Slater, Holli, Soutullo, Cesar A., Hettema, John M., Azhar, Nisha A., Goodman, Wayne K., Trivedi, Maduhkar H., and Storch, Eric A.

Published
2024
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19. Deep Brain Stimulation for Obsessive-Compulsive Disorder: Optimal Stimulation Sites

Author

Meyer, Garance M., Hollunder, Barbara, Li, Ningfei, Butenko, Konstantin, Dembek, Till A., Hart, Lauren, Nombela, Cristina, Mosley, Philip, Akram, Harith, Acevedo, Nicola, Borron, Benjamin M., Chou, Tina, Castaño Montoya, Juan Pablo, Strange, Bryan, Barcia, Juan A., Tyagi, Himanshu, Castle, David J., Smith, Andrew H., Choi, Ki Sueng, Kopell, Brian H., Mayberg, Helen S., Sheth, Sameer A., Goodman, Wayne K., Leentjens, Albert F.G., Richardson, R. Mark, Rossell, Susan L., Bosanac, Peter, Cosgrove, G. Rees, Kuhn, Jens, Visser-Vandewalle, Veerle, Figee, Martijn, Dougherty, Darin D., Siddiqi, Shan H., Zrinzo, Ludvic, Joyce, Eileen, Baldermann, Juan Carlos, Fox, Michael D., Neudorfer, Clemens, and Horn, Andreas

Published
2024
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35. Decoding Depression Severity From Intracranial Neural Activity

Author

Xiao, Jiayang, Provenza, Nicole R., Asfouri, Joseph, Myers, John, Mathura, Raissa K., Metzger, Brian, Adkinson, Joshua A., Allawala, Anusha B., Pirtle, Victoria, Oswalt, Denise, Shofty, Ben, Robinson, Meghan E., Mathew, Sanjay J., Goodman, Wayne K., Pouratian, Nader, Schrater, Paul R., Patel, Ankit B., Tolias, Andreas S., Bijanki, Kelly R., Pitkow, Xaq, and Sheth, Sameer A.

Published
2023
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37. Patient, Caregiver, and Decliner Perspectives on Whether to Enroll in Adaptive Deep Brain Stimulation Research.

Author

Outram, Simon, Muñoz, Katrina A, Kostick-Quenet, Kristin, Sanchez, Clarissa E, Kalwani, Lavina, Lavingia, Richa, Torgerson, Laura, Sierra-Mercado, Demetrio, Robinson, Jill O, Pereira, Stacey, Koenig, Barbara A, Starr, Philip A, Gunduz, Aysegul, Foote, Kelly D, Okun, Michael S, Goodman, Wayne K, McGuire, Amy L, Zuk, Peter, and Lázaro-Muñoz, Gabriel

Subjects
aDBS, altruism, decision-making, interviews, quality of life, research, study design, symptoms, Aging, Behavioral and Social Science, Clinical Research, No Poverty, Neurosciences, Psychology, Cognitive Sciences
Abstract

This research study provides patient and caregiver perspectives as to whether or not to undergo adaptive deep brain stimulation (aDBS) research. A total of 51 interviews were conducted in a multi-site study including patients undergoing aDBS and their respective caregivers along with persons declining aDBS. Reasons highlighted for undergoing aDBS included hopes for symptom alleviation, declining quality of life, desirability of being in research, and altruism. The primary reasons for not undergoing aDBS issues were practical rather than specific to aDBS technology, although some persons highlighted a desire to not be the first to trial the new technology. These themes are discussed in the context of "push" factors wherein any form of surgical intervention is preferable to none and "pull" factors wherein opportunities to contribute to science combine with hopes and/or expectations for the alleviation of symptoms. We highlight the significance of study design in decision making. aDBS is an innovative technology and not a completely new technology. Many participants expressed value in being part of research as an important consideration. We suggest that there are important implications when comparing patient perspectives vs. theoretical perspectives on the choice for or against aDBS. Additionally, it will be important how we communicate with patients especially in reference to the complexity of study design. Ultimately, this study reveals that there are benefits and potential risks when choosing a research study that involves implantation of a medical device.

Published
2021

38. Anxiety in Angelman Syndrome

Author

Grebe, Stacey C., Limon, Danica L., McNeel, Morgan M., Guzick, Andrew, Peters, Sarika U., Tan, Wen-Hann, Sadhwani, Anjali, Bacino, Carlos A., Bird, Lynne M., Samaco, Rodney C., Berry, Leandra N., Goodman, Wayne K., Schneider, Sophie C., and Storch, Eric A.

Abstract

Angelman Syndrome (AS) is a neurodevelopmental disorder most commonly caused by the impaired expression of the maternal "UBE3A" gene on chromosome 15. Though anxiety has been identified as a frequently present characteristic in AS, there are limited studies examining anxiety in this population. Studies of anxiety in other neurodevelopmental disorders have found disorder specific symptoms of anxiety and age specific displays of anxiety symptoms. However, there is a consistent challenge in identifying anxiety in people with neurodevelopmental disorders given the lack of measurement instruments specifically designed for this population. Given the limited information about AS and anxiety, the aims of the current project were to: (1) examine symptoms of anxiety in children with AS; and (2) determine the correlates of anxiety in children with AS. Participants included 42 adult caregivers of youth with AS in the AS Natural History study who completed the Developmental Behavior Checklist (DBC). The results found that 26% of the sample demonstrated elevated symptoms of anxiety and established a relationship between elevated anxiety in youth with AS and higher levels of irritability, hyperactivity, self-absorbed behaviors, and disruptive/antisocial behaviors. Findings from this research provide a foundation for tailoring evidence-based assessments and treatments for youth with AS and anxiety.

Published
2022
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46. Insula uses overlapping codes for emotion in self and others

Author

Xiao, Jiayang, primary, Adkinson, Joshua A., additional, Allawala, Anusha B., additional, Banks, Garrett, additional, Bartoli, Eleonora, additional, Fan, Xiaoxu, additional, Mocchi, Madaline, additional, Pascuzzi, Bailey, additional, Pulapaka, Suhruthaa, additional, Franch, Melissa C., additional, Mathew, Sanjay J., additional, Mathura, Raissa K., additional, Myers, John, additional, Pirtle, Victoria, additional, Provenza, Nicole R., additional, Shofty, Ben, additional, Watrous, Andrew J., additional, Pitkow, Xaq, additional, Goodman, Wayne K., additional, Pouratian, Nader, additional, Sheth, Sameer A., additional, Bijanki, Kelly R., additional, and Hayden, Benjamin Y., additional

Published
2024
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