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3. Magnetic Nanoparticles for Power Absorption: optimizing size, shape and magnetic properties

Author

Gonzalez-Fernandez, M. A., Torres, T., Andres-Verges, M., Costo, R., de la Presa, P., Serna, C. J., Morales, M. P., Marquina, C., Ibarra, M. R., and Goya, G. F.

Subjects
Condensed Matter - Materials Science
Abstract

We present a study on the magnetic properties of naked and silica-coated Fe3O4 nanoparticles with sizes between 5 and 110 nm. Their efficiency as heating agents was assessed through specific power absorption (SPA) measurements as a function of particle size and shape. The results show a strong dependence of the SPA with the particle size, with a maximum around 30 nm, as expected for a Neel relaxation mechanism in single-domain particles. The SiO2 shell thickness was found to play an important role in the SPA mechanism by hindering the heat outflow, thus decreasing the heating efficiency. It is concluded that a compromise between good heating efficiency and surface functionality for biomedical purposes can be attained by making the SiO2 functional coating as thin as possible., Comment: 15 pages, 7 figures, 2 tables

Published
2009
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4. Mitochondrial heteroplasmy as a marker for premature coronary artery disease: analysis of the poly-C tract of the control region sequence

Author

Gonzalez Urbistondo, F, primary, Aparicio-Gavilanes, A, additional, Gomez, J, additional, Alvarez-Velasco, R, additional, Pascual, I, additional, Avanzas, P, additional, Alen, A, additional, Vazquez-Coto, M, additional, Gonzalez-Fernandez, M, additional, Garcia-Largo, C, additional, Cuesta-Llavona, E, additional, Moris De La Tassa, C, additional, Eliecer, C, additional, and Lorca, R, additional

Published
2023
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7. List of Contributors

Author

Boden-Albala, Bernadette, primary, Kwah, Li Khim, additional, Galletta, Elizabeth E., additional, Goral, Mira, additional, Conner, Peggy S., additional, Gonzalez-Fernandez, M., additional, Barrett, A.M., additional, Wilson, Richard, additional, Treister, Andrew K., additional, Raghavan, Preeti, additional, Lee, John J., additional, Francisco, Gerard E., additional, Jorge, Ricardo E., additional, Rizzo, John-Ross, additional, Flanagan, Steven R., additional, Fu, Michael J., additional, Knutson, Jayme S., additional, Von Koch, Lena, additional, Eriksson, Gunilla Margareta, additional, Johansson, Ulla, additional, Akinwuntan, Abiodun, additional, Stein, Joel, additional, Barbuto, Scott, additional, Cunningham, David A., additional, Holman, Lainie K., additional, Plow, Matthew A., additional, Li, Sheng, additional, Thomas, Jonathan Oen, additional, Appleton, Noa, additional, Schram, Benjamin, additional, Langton-Frost, N., additional, Bahouth, M.N., additional, Wright, A.N., additional, Karagiorgos, E., additional, Chae, John, additional, Jones, Melissa, additional, Kapoor, Neera, additional, Fusco, Heidi, additional, Devos, Hannes, additional, Potter–Baker, Kelsey A., additional, Plow, Ela B., additional, Chang, Julia, additional, Chang, Eric Y., additional, Lin, Yin-Liang, additional, Kwakkel, Gert, additional, Veerbeek, Janne M., additional, and Beheshti, Mahya, additional

Published
2019
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10. OMERACT agreement and reliability study of ultrasonographic elementary lesions in osteoarthritis of the foot

Author

Zabotti, A, Filippou, G, Canzoni, M, Adinolfi, A, Picerno, V, Carrara, G, Balint, P, Bruyn, G, D'Agostino, M, Damjanov, N, Delle Sedie, A, Filippucci, E, Gonzalez Fernandez, M, Hammer, H, Karim, Z, Mandl, P, Moller, I, Morales Lozano, M, Naredo, E, Porta, F, Sakellariou, G, Terslev, L, Scire, C, Iagnocco, A, Zabotti A., Filippou G., Canzoni M., Adinolfi A., Picerno V., Carrara G., Balint P., Bruyn G., D'Agostino M. A., Damjanov N., Delle Sedie A., Filippucci E., Gonzalez Fernandez M. L., Hammer H. B., Karim Z., Mandl P., Moller I., Morales Lozano M. R., Naredo E., Porta F., Sakellariou G., Terslev L., Scire C. A., Iagnocco A., Zabotti, A, Filippou, G, Canzoni, M, Adinolfi, A, Picerno, V, Carrara, G, Balint, P, Bruyn, G, D'Agostino, M, Damjanov, N, Delle Sedie, A, Filippucci, E, Gonzalez Fernandez, M, Hammer, H, Karim, Z, Mandl, P, Moller, I, Morales Lozano, M, Naredo, E, Porta, F, Sakellariou, G, Terslev, L, Scire, C, Iagnocco, A, Zabotti A., Filippou G., Canzoni M., Adinolfi A., Picerno V., Carrara G., Balint P., Bruyn G., D'Agostino M. A., Damjanov N., Delle Sedie A., Filippucci E., Gonzalez Fernandez M. L., Hammer H. B., Karim Z., Mandl P., Moller I., Morales Lozano M. R., Naredo E., Porta F., Sakellariou G., Terslev L., Scire C. A., and Iagnocco A.

Abstract

Objective To evaluate the level of agreement on ultrasonographic (US) lesions among highly experienced sonographers as well as the intraobserver and interobserver reliability of inflammatory and structural US lesions in patients with osteoarthritis (OA) of the foot. Methods After a systematic literature review, a Delphi survey was performed to test definitions of US lesions in OA of the foot, including inflammatory lesions (ie, synovial hypertrophy [SH], joint effusion [JE], power Doppler signal [PD]), and structural abnormalities (ie, cartilage damage [CD] and osteophytes). Subsequently, the reliability of US in assessing the aforementioned lesions was tested on static images as well as during a live exercise. Reliability was assessed by kappa analyses and prevalence-adjusted bias-adjusted kappa (PABAK) on a dichotomous and an ordinal scale. Results Intraobserver and interobserver reliability for SH and JE evaluated by binary scoring was good for both components, while the intraobserver reliability for semiquantitative scoring of SH ranged from moderate in the web-based exercise (PABAK 0.49) to good (PABAK 0.8) in the live exercise. Reliability for CD and PD assessments were respectively good and excellent in all exercises (ranged from PABAK 0.61 to 0.79 for CD and 0.88 to 0.95 for PD). The interobserver reliability for the semiquantitative scoring of osteophytes was fair in the live exercise (PABAK 0.36) and moderate in the static exercise (PABAK 0.60). Conclusions Consensual US definitions were found to be reliable for assessing inflammatory lesions in OA of the foot, while the use of US to assess structural damage requires further studies.

Published
2019

16. 1516P Health-related quality of life (hrqol) analysis from KEYNOTE-859: First-line (1L) pembrolizumab (pembro) + chemotherapy (chemo) for advanced HER2-negative gastric or gastroesophageal junction (G/GEJ) adenocarcinoma

Author

Lowery, M., Wyrwicz, L., Oh, D-Y., Shiu, K-K., Yanez Weber, P., Bai, Y., Lee, J., Rivera, F., Alves, G., Garrido, M., González Fernández, M., Li, J., Cil, T., Cruz, F., Qin, S., Yin, L., Valderrama, A., Bordia, S., and Rha, S.Y.

Published
2023
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17. Hyperlipoproteinaemia(a) in patients with spondyloarthritis: results of the Cardiovascular in Rheumatology (CARMA) project

Author

Garcia-Gomez, C, Martin-Martinez, M, Fernandez C, Castaneda, S, Gonzalez-Juanatey, C, Sanchez-Alonso, F, Gonzalez-Fernandez, M, Sanmarti, R, Garcia-Vadillo, J, Fernandez-Gutierrez, B, Garcia-Arias, M, Manero, F, Senabre, J, Rueda-Cid, A, Ros-Exposito, S, Pina-Salvador, J, Erra-Duran, A, Moller-Parera, I, Llorca, J, Gonzalez-Gay, M, Gonzalez de Rabago, E, Blanco Morales, E, Fernandez Lopez, J, Oreiro Villar, N, Atanes Sandoval, A, Blanco Garcia, F, Alegre De Miquel, C, Gonzalez Fernandez, M, Huguet Codina, R, Yoldi, B, Ramentol, M, Avila, G, Marsal Barril, S, Steiner, M, Munoz, S, Gamero, F, Garcia Toron, J, Moreno Gil, M, Mas, A, Espino, P, Ros, I, Ibanez, M, Murillo, C, Piqueras, J, Berman, H, Cabrera, S, Ruiz, V, Fontsere Paton, O, Fernandez Gutierrez, B, Abasolo, L, Fabregas, M, Romera Baures, M, Nolla, J, Gonzalez-Alvaro, I, Tomero Muriel, E, Garcia de Vicuna, R, Fernandez Nebro, A, Belmonte Lopez, M, Urena, I, Irigoyen, M, Coret Cagigal, V, Lopez Gonzalez, R, Pielfort Garrido, D, Sampedro Alvarez, J, Garcia Aparicio, A, Belmonte Gomez, R, Granados Bautista, P, Hernandez Sanz, A, Sanchez Gonzalez, C, Bachiller, J, Zea, A, Jimenez Zorzo, F, Gimenez Ubeda, E, Marzo Gracia, J, Beltran Audera, C, Medrano, M, Pecondon, A, Erausquin, C, Ojeda, S, Carlos Quevedo, J, Francisco, F, Rodriguez Lozano, C, Babio Herraez, J, Lopez Longo, F, Gerona, D, Gonzalez Fernandez, C, Carreno, L, Monteagudo, I, del Pino, J, Sanchez Gonzalez, M, Corrales, A, Enriqueta Peiro, M, Rosas, J, Rotes, I, Moreno, E, Erra, A, Grado, D, Calvo, J, Rueda, A, Moller, I, Rodriguez, I, Barbadillo, C, Raya, E, Morales, P, Nieto, A, Jimenez, I, Magro, C, Ruibal Escribano, A, Ros Exposito, S, Sanchez Nievas, G, Judez Navarro, E, Sianes Fernandez, M, Garcia Morales, M, Labiano Bastero, I, Consuegra, G, Palmou, N, Martinez Pardo, S, Pujol, M, Riera Alonso, E, Salvador, G, Gonzalez Alvarez, B, Cantabrana, A, Bustabad, S, Delgado, E, Munoz, A, Rodriguez Montero, S, Maria Jimenez, L, Rivera Redondo, J, Gonzalez Hernandez, T, Gonzalez Polo, F, Menor Almagro, R, Moreno, J, Giner Serret, E, Lannuzzelli Barroso, C, Cebrian Mendez, L, Teresa Navio, M, Fernandez Carballido, C, Pagan, E, Mesa del Castillo, P, Naredo, E, Cruz, A, Turrion, A, Mateo, I, Sanchez, J, Galindo, M, Garcia Gonzalez, J, Collantes, E, Ruiz, D, Font, P, Bonilla, G, Lopez Meseguer, A, Moreno, M, Moreno Martinez, M, Beteta Fernandez, M, Linares, L, Morcillo, M, Gonzalez Gomez, M, Aramburu, J, Rivera, N, Fernandez Berrizbeitia, O, Garcia Vivar, M, Riera, M, Maria Leon, Y, Maymo, J, Amirall, M, Iniesta Escolano, S, Sanchez Serrano, S, Lis Bona, M, Fiter, J, Fernandez Melon, J, Espadaler, L, Maiz, O, Belzunegui, J, Banegil, I, Diaz, C, Valls, R, Castellvi, I, Bonet, M, Moreno Ruzafa, E, Calvo Alen, J, Perez Sandoval, T, Revuelta Evrard, E, Godo, J, Fernandez Espartero, C, Navarro Blasco, F, Antonio Gonzalez, J, Miranda-Filloy, J, and CARMA Project Collaborative Grp

Subjects
musculoskeletal diseases, psoriatic arthritis, lipids, stomatognathic diseases, cardiovascular disease, lipoprotein(a), ankylosing spondylitis, spondyloarthritis
Abstract

Objective Cardiovascular (CV) disease is one of the main causes of morbi-mortality in spondyloarthritis (SpA), partially explained by traditional CV risk factors. Information on lipoprotein(a) [Lp(a)], a non-conventional risk factor, in SpA is scarce. In this study we assessed the prevalence of hyperlipoproteinaemia(a) in SpA patients and analysed the possible related factors. Methods A baseline analysis was made of ankylosing spondylitis (AS) and psoriatic arthritis (PsA) patients and controls included in the CARMA project (CARdiovascular in RheuMAtology), a 10-year prospective study evaluating the risk of CV events in chronic inflammatory rheumatic diseases. A multivariate logistic regression model was performed using hyperlipoproteinaemia( a) (Lp(a) >50 mg/dl) as a dependent variable and adjusting for confounding factors. Results 19.2% (95% CI: 16.80-22.05) of the SpA patients [20.7% (95% CI: 16.91-24.82) of those with AS and 17.7% (95% CI: 14.15-21.75) of those with PsA] and 16.7% (95% CI: 13.23-20.86) of the controls had hyperlipoproteinaemia(a) (p=0.326). Adjusting for age and sex, SpA patients were more likely to have hyperlipoproteinaemia(a) than controls (OR: 1.43, 95% CI: 1.00-2.04; p=0.05), especially those with AS (OR: 1.81, 95% CI: 1.18-2.77; p=0.007). In the adjusted model, apolipoprotein B in all patients, non-steroidal anti-inflammatory drugs in AS, and female sex in PsA, were associated with hyperlipoproteinaemia(a). No disease-specific factors associated with hyperlipoproteinaemia(a) were identified. Conclusion SpA patients show a moderately increased risk of hyperlipoproteinaemia(a) compared to controls, especially those with AS. Lp(a) determination may be of interest to improve the CV risk assessment in SpA patients.

Published
2019

18. Incidence of First Cardiovascular Event in Spanish Patients with Chronic Inflammatory Rheumatic Diseases. Prospective Data After Five Years of Follow Up

Author

Martin-Martinez M, Castaneda S, Sanchez-Alonso F, Garcia-Gomez C, Juanatey C, Belmonte-Lopez M, Tornero-Molina J, Santos-Rey J, Sanchez-Gonzalez C, Moreno E, Moreno-Gil M, Cobo-Ibanez T, Pinto-Tasende J, Babio-Herraez J, Bonilla G, Juan-Mas A, Manero-Ruiz F, Romera-Baures M, Bachiller-Corral J, Chamizo-Carmona E, Calvo-Catalan J, Sanmarti R, Erausquin-Arruabarrena C, Garcia-Vicuna R, Barbadillo C, Ros-Exposito S, Turrion A, Gonzalez-Fernandez M, Senabre J, Martinez-Pardo S, Ruibal-Escribano A, Giner-Serret E, Berzosa-Sola E, Martinez-Barrio J, Pagan E, Enriqueta-Peiro M, Bustabad-Reyes S, Erra-Duran A, Alvarez B, Valenciano A, Rivera-Redondo J, Ramos M, Montero S, Morcillo-Valle M, Navio M, Galindo-Izquierdo M, Riera-Soler M, Fiter J, Llorca J, and Gonzalez-Gay M

Published
2020

20. Decrease in the thickness of the masseter muscle during the hospital stay in relation to the texture of the prescribed diet

Author

Sanz-Paris, A., primary, Franco Rubio, L., additional, Gonzalez Fernandez, M., additional, Calmarza Chueca, F., additional, Sanclemente, T., additional, Garcia Hoyos, V., additional, Monge Vazquez, A., additional, Huici Polo, P., additional, Hueso Del Rio, L.E., additional, Sanz-Arque, A., additional, and Arbones Mainar, J.M., additional

Published
2020
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22. Evolution of the analytical nutritional parameters of conut throughout hospital admission for hip fracture.

Author

Sanz-Paris, A., primary, Trincado Cobos, P., additional, Calmarza, P., additional, Cassinello, M.C., additional, Hueso Del Rio, L.E., additional, Lasso Olayo, J.M., additional, Gonzalez Irazabal, Y., additional, Gonzalez Fernandez, M., additional, Garcia Navalon, P., additional, Sanz Arque, A., additional, and Arbones Mainar, J.M., additional

Published
2020
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26. The comparative responsiveness of Hospital Universitario Princesa Index and other composite indices for assessing rheumatoid arthritis activity

Author

Gonzalez-Alvaro, Isidoro, Castrejon, Isabel, Carmona, Loreto, Dougados, M., Huizinga, T., Abu Shakra, M., Alberts, A., Alperi Lopez, M., Amital, H., Aringer, M., Aslanidis, S., Berenbaum, F., Bijlsma, H., Blanco Garcia, F. J., Bliddal, H., Borofsky, M., Brocq, O., Buldakov, S., Cantini, F., Carreno Perez, L., Chahade, W., Ciconelli, R., Codreanu, C., Dahlqvist, S. R., Damjanov, N., Diamantopoulos, A., Dimdina, L., Dimic, A., Dorokhov, A., Dubikov, A., Fadienko, G., Fano, N., Ferreira, G., Gabrielli, A., Gaffney, K., Gaudin, P., Gerlag, D. M., Gerli, R., Goncalves, C. R., Hansen, M. S., Hanvivadhanakul, P., Hoili, C., Hou, A., Hunter, J., Ilic, T., Ionescu, R., Kaine, J., Kakurina, N., Kamalova, R., Kelly, T., Knyazeva, L., Krumina, L., Kurthen, R., Lagrone, R. P., Lapadula, G., Lavrentjevs, V, Lawson, J. G., Lazic, Z., Lejnieks, A., Levy, Y., Lexberg, A., Mader, R., Mariette, X., Markovits, D., Mola, Martin E., Maugars, Y., Guarch, Maymo J., Mazurov, V., I, Mikkelsen, K., Vergles, Morovic J., Nabizadeh, S., Nanagara, R., Nasonov, E. L., Sarabia, Navarro F., Neumann, T., Novak, S., Olech, E., Oza, M., Paran, D., Parsik, E., Pegram, S., Suarez, Pombo M., Popova, T., Puechal, X., Raja, N., Ridley, D., Rosner, I, Rubbert-Roth, A., Rudin, A., Saraux, A., Saulite-Kandevica, D., Settas, L., Sfikakis, P., Sheeran, T., Sizikov, A., Stamenkovic, D., Stefanovic, D., Stolow, J. B., Tan, A. L., Tebib, J., Tishler, M., Tony, H. P., Troum, O. M., Uaratanawong, S., Ucar Angulo, E., Valenzuela, G., van der Laken, K., Van Laar, J., van Riel, P. L. C. M., Vasilopoulos, D., Veldi, T., Vinogradova, I, Vosse, D., Wassenberg, S., Weidmann, C., Weitz, M., Wollenhaupt, J., Xavier, R., Yakupova, S., Zagar, I, Zavgorodnaja, T., Zemerova, E., Zisman, D., Zonova, E., Camona, Loreto, Abasolo Alcazar, L., Alegre de Miguel, C., Andreu Sanchez, J. L., Aragon Diez, A., Balsa Criado, A., Batlle Gualda, E., Belmonte Serrano, M. A., Beltran Audera, J., Beltran Fabregat, J., Bonilla Hernan, G., Caro Fernandez, N., Casado, E., Cebrian Mendez, L., Corteguera Coro, M., Cuadra Diaz, J. L., Cuesta, E., Fiter Areste, J., Freire Gonzalez, M., Galindo Izquierdo, M., Garcia Meijide, J. A., Garcia Gomez, M. C., Gimenez Ubeda, E., Gomez Centeno, E., Gomez Vaquero, C., Gonzalez Fernandez, M. J., Gonzalez Gomez, M. L., Gonzalez Hernandez, T., Gonzalez-Alvaro, I, Gonzalez-Montagut Gomez, C., Grandal Delgado, Y., Gratacos Masmitja, J., Hernandez del Rio, A., Instxaurbe, A. R., Irigoyen Oyarzabal, M., V, Jimenez Palop, M., Juan Mas, A., Judez Navarro, E., Larrosa Padro, M., Lopez Longo, F. J., Loza Santamaria, E., Maese Manzano, J., Manero Ruiz, F. J., Mateo Bernardo, I, Mayordomo Gonzalez, L., Mazzucheli, R., Medrano San Idelfonso, M., Naranjo Hernandez, A., Pecondon Espanol, A., Peiro Callizo, E., Quiros Donate, J., Ramos Lopez, P., Rivera Redondo, J., Rodriguez Gomez, M., Rodriguez Lopez, M., Rosello Pardo, R., Sampedro Alvarez, J., Sanmarti Sala, R., Rey Rey, Santos J., Tena Marsa, X., Tenorio Martin, M., Torres Martin, M. C., Urena Garnica, I, Valdazo de Diego, J. P., Valls, M., Villaverde Garcia, V., Zarco Montejo, P., Zubieta Tabernero, J., Balsa, Alejandro, Sanmarti, Raimon, Cabezas, J. A., Cantalejo, M., Chamizo, E., Ciruelo, E., Corrales, A., Cruz, A., Diaz, C., Fiter, J., Freire, M. M., Galindo, M., Garcia de Vicuna, M. R., Gelman, S. M., Gonzalez Crespo, R., Gonzalez Fernandez, C., Gracia, A., Granados, J., Guzman, M. A., Irigoyen, M., V, Juan, A., Juanola, X., Laiz, A., Manero, F. J., Martinez, A., Martinez, F., Mata, C., Maymo, J., Navarro, F. J., Peiro, E., Perez, F., Perez, G., Perez, M., Pujol, M., Quiros, J., Ribas, B., Riera, M., Rivera, J., Rodriguez, J. M., Rosello, R., Tenorio, M., Toyos, F. J., ACT-RAY Study Grp, PROAR Study Grp, EMECAR Study Grp, Interne Geneeskunde, MUMC+: MA Reumatologie (9), and RS: CAPHRI - R3 - Functioning, Participating and Rehabilitation

Subjects
Male, medicine.medical_specialty, Science, humanos, Severity of Illness Index, RECOMMENDATIONS, VALIDATION, VARIABLES, ensayos clínicos como asunto, Arthritis, Rheumatoid, Cohort Studies, Internal medicine, Linear regression, Severity of illness, medicine, Humans, índice de gravedad de la enfermedad, estudios de cohortes, mediana edad, Clinical Trials as Topic, DISEASE-ACTIVITY MEASURES, Multidisciplinary, SCORES, business.industry, Arthritis, resultado del tratamiento, modelos lineales, Secondary data, Gold standard (test), Middle Aged, medicine.disease, Clinical trial, Treatment Outcome, Rheumatoid arthritis, Antirheumatic Agents, Cohort, Linear Models, Medicine, Female, GENDER, business, antirreumáticos, artritis, Cohort study
Abstract

Objective To evaluate the responsiveness in terms of correlation of the Hospital Universitario La Princesa Index (HUPI) comparatively to the traditional composite indices used to assess disease activity in rheumatoid arthritis (RA), and to compare the performance of HUPI-based response criteria with that of the EULAR response criteria. Methods Secondary data analysis from the following studies: ACT-RAY (clinical trial), PROAR (early RA cohort) and EMECAR (pre-biologic era long term RA cohort). Responsiveness was evaluated by: 1) comparing change from baseline (Delta) of HUPI with Delta in other scores by calculating correlation coefficients; 2) calculating standardised effect sizes. The accuracy of response by HUPI and by EULAR criteria was analyzed using linear regressions in which the dependent variable was change in global assessment by physician (Delta GDA-Phy). Results Delta HUPI correlation with change in all other indices ranged from 0.387 to 0.791); HUPI's standardized effect size was larger than those from the other indices in each database used. In ACT-RAY, depending on visit, between 65 and 80% of patients were equally classified by HUPI and EULAR response criteria. However, HUPI criteria were slightly more stringent, with higher percentage of patients classified as non-responder, especially at early visits. HUPI response criteria showed a slightly higher accuracy than EULAR response criteria when using Delta GDA-Phy as gold standard. Conclusion HUPI shows good responsiveness in terms of correlation in each studied scenario (clinical trial, early RA cohort, and established RA cohort). Response criteria by HUPI seem more stringent than EULAR's., Our study was supported by grants RD16/0012/0011 and PI14/00442 from the Ministerio de Economia y Competitividad (Instituto de Salud Carlos III; Spain) and cofunded by the Fondo Europeo de Desarrollo Regional (FEDER). Data from ACT-RAY clinical trial were kindly provided by Hoffmann-La Roche Ltd. No financial support was received from Hoffmann-La Roche Ltd Data from EMECAR and PROAR cohorts were provided by the Spanish Society of Rheumatology. No financial support was received from the Spanish Society of Rheumatology. None of these institutions played any role in the analysis or interpretation of data, nor were they involved in the writing of the manuscript. Roche and Sociedad Espanola de Reumatologia were involved in the collection of data from ACT-RAY, and EMECAR and PROAR, respectively. However, these funders had no role in study design, analysis, decision to publish, or preparation of the manuscript.

Published
2019

27. List of Contributors

Author

Beheshti, Mahya, Devos, Hannes, Langton-Frost, N., Schram, Benjamin, Wilson, Richard, Wright, A.N., Rizzo, John-Ross, Goral, Mira, Akinwuntan, Abiodun, Plow, Matthew A., Stein, Joel, Barrett, A.M., Fusco, Heidi, Lee, John J., Kwakkel, Gert, Lin, Yin-Liang, Potter–Baker, Kelsey A., Gonzalez-Fernandez, M., Galletta, Elizabeth E., Jorge, Ricardo E., Fu, Michael J., Barbuto, Scott, Eriksson, Gunilla Margareta, Kapoor, Neera, Kwah, Li Khim, Cunningham, David A., Chae, John, Appleton, Noa, Chang, Eric Y., Bahouth, M.N., Raghavan, Preeti, Treister, Andrew K., Johansson, Ulla, Holman, Lainie K., Li, Sheng, Chang, Julia, Veerbeek, Janne M., Boden-Albala, Bernadette, Jones, Melissa, Thomas, Jonathan Oen, Knutson, Jayme S., Conner, Peggy S., Plow, Ela B., Karagiorgos, E., Von Koch, Lena, Flanagan, Steven R., Francisco, Gerard E., Rehabilitation medicine, and Amsterdam Movement Sciences - Restoration and Development

Published
2019
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29. OMERACT agreement and reliability study of ultrasonographic elementary lesions in osteoarthritis of the foot

Author

Zabotti, A., Filippou, G., Canzoni, M., Adinolfi, Annalisa, Picerno, V., Carrara, Giancarlo, Balint, P., Bruyn, G., D'Agostino, Maria Antonietta, Damjanov, N., Delle Sedie, A., Filippucci, E., Gonzalez Fernandez, M. L., Hammer, H. B., Karim, Z., Mandl, P., Moller, I., Morales Lozano, M. R., Naredo, E., Porta, F., Sakellariou, G., Terslev, L., Scire, C. A., Iagnocco, A., Adinolfi A., Carrara G., D'Agostino M. A. (ORCID:0000-0002-5347-0060), Zabotti, A., Filippou, G., Canzoni, M., Adinolfi, Annalisa, Picerno, V., Carrara, Giancarlo, Balint, P., Bruyn, G., D'Agostino, Maria Antonietta, Damjanov, N., Delle Sedie, A., Filippucci, E., Gonzalez Fernandez, M. L., Hammer, H. B., Karim, Z., Mandl, P., Moller, I., Morales Lozano, M. R., Naredo, E., Porta, F., Sakellariou, G., Terslev, L., Scire, C. A., Iagnocco, A., Adinolfi A., Carrara G., and D'Agostino M. A. (ORCID:0000-0002-5347-0060)

Abstract

Objective To evaluate the level of agreement on ultrasonographic (US) lesions among highly experienced sonographers as well as the intraobserver and interobserver reliability of inflammatory and structural US lesions in patients with osteoarthritis (OA) of the foot. Methods After a systematic literature review, a Delphi survey was performed to test definitions of US lesions in OA of the foot, including inflammatory lesions (ie, synovial hypertrophy [SH], joint effusion [JE], power Doppler signal [PD]), and structural abnormalities (ie, cartilage damage [CD] and osteophytes). Subsequently, the reliability of US in assessing the aforementioned lesions was tested on static images as well as during a live exercise. Reliability was assessed by kappa analyses and prevalence-adjusted bias-adjusted kappa (PABAK) on a dichotomous and an ordinal scale. Results Intraobserver and interobserver reliability for SH and JE evaluated by binary scoring was good for both components, while the intraobserver reliability for semiquantitative scoring of SH ranged from moderate in the web-based exercise (PABAK 0.49) to good (PABAK 0.8) in the live exercise. Reliability for CD and PD assessments were respectively good and excellent in all exercises (ranged from PABAK 0.61 to 0.79 for CD and 0.88 to 0.95 for PD). The interobserver reliability for the semiquantitative scoring of osteophytes was fair in the live exercise (PABAK 0.36) and moderate in the static exercise (PABAK 0.60). Conclusions Consensual US definitions were found to be reliable for assessing inflammatory lesions in OA of the foot, while the use of US to assess structural damage requires further studies.

Published
2019

30. Prevention and early diagnosis of childhood osteoporosis: are we doing the right thing?

Author

Mir-Perello, C., Galindo Zavala, R., Gonzalez Fernandez, M., I, Grana Gil, J., Sevilla Perez, Magallares Lopez, B., Bou Torrent, R., Grp Trabajo Osteoporosis Infantil, and Osteogenesis Imperfecta Sociedad E

Subjects
early diagnosis of osteoporosis, osteoporosis prevention, bone health
Abstract

Objectives: To assess prevention, early diagnosis and training received regarding osteoporosis among the pediatrics professionals in our area. Material and methods: Survey directed to physicians of pediatricians of Primary Care (PC) and Specialized Care (SC) in order to evaluate their activity in prevention, detection and training received in osteoporosis. The survey was disseminated through the relevant scientific societies. Results: 420 pediatricians participated (324 from PC and 96 from SC). 93.5% of PC pediatricians and 89.6% of SC pediatricians valued the physical activity of the patients; 85.19% and 35.4% of them, respectively, the intake of dairy products. 45.68% of PC and 70.2% of SC recommended calcium and vitamin D supplements in the case of low nutritional intake, whereas 39.2% of PC and 47.2% of SC favored follow-up. 39.6% of SC pediatricians requested bone densitometry for this disease or risk treatment, and 47.9% measured the levels of 25-OH-vitamin D. 25.93% of PC and 45.3% of SC asked about the existence of fractures, 90.4% and 96.8% requested etiopathogenic mechanism. 40% of PC and 86.2% of SC requested a bone densitometry or referred to the specialist for fractures due to low trauma energy, with specific criteria in 13.7% and 5.86%, respectively. 92% of PC and 82.3% of SC had not received recent training in childhood osteoporosis. Conclusion: Detection, derivation circuits and the training of pediatricians regarding bone health in our country can be improved. Optimizing these aspects is essential to favor the peak of bone mass in our population.

Published
2018

31. SUN-PO243: Results of a Survey on the Quality of the Basal Diet in Hospitalized Patients and their Relationship with their Nutritional Status

Author

Sanz-Paris, A., primary, Díaz-Laguardia, N., additional, Calvera-Supervia, B., additional, Losfablos-Callau, F., additional, Gonzalez-Fernandez, M., additional, Sanz-Arque, A., additional, Arbones-Mainar, J.-M., additional, Bimbela Serrano, M.-T., additional, Garcia-Navalon, P., additional, Lopez-Alaminos, M.-E., additional, and Alvarado-Rosas, K.-A., additional

Published
2019
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35. Texture and viscosity effects in particulate recording media

Author

Gonzalez-Fernandez, M. A.; Sharrock, M. P., Blocksidge, G.; Seftick, D., Bunce, C., O'Grady, K., and el-Hilo, M.

Subjects
Viscosity -- Analysis, Storage media -- Properties, Thermal analysis, Physics
Abstract

A magnetic texture in a tape that is fabricated with varying orientation of the long axes of the particles is studied. A strong correlation to the texture with implications for thermal loss effects is seen in the studies of the switching field distribution of the particles in the tape and magnetic viscosity.

Published
2005

38. Magnetic Nanoparticles for Power Absorption: optimizing size, shape and magnetic properties.

Author

Gonzalez Fernandez, M. A., Torres, T., Andrés Vergés, M., Costo, R., Presa Muñoz del Toro, Patricia de la, Serna, C. J., Morales, M. P., Marquina, C., Ibarra, M. R., Goya, G. F., Gonzalez Fernandez, M. A., Torres, T., Andrés Vergés, M., Costo, R., Presa Muñoz del Toro, Patricia de la, Serna, C. J., Morales, M. P., Marquina, C., Ibarra, M. R., and Goya, G. F.

Abstract

©Elsevier. The authors acknowledge the financial support from Diputación General de Aragón, Comunidad de Madrid (S-0505/MAT/0194), and Ministerio de Ciencia e Innovación (MAT2005-03179 and MAT2008-01489). GFG and PP acknowledge support from the Spanish MEC through the Ramon y Cajal program., We present a Study on the magnetic properties of naked and silica-coated Fe₃O₄nanoparticles with sizes between 5 and 110 nm. Their efficiency as heating agents was assessed through specific power absorption (SPA) measurements as a function of particle size and shape. The results show a strong dependence of the SPA with the particle size, with a maximum around 30 nm, as expected for a Neel relaxation mechanism in single-domain particles. The SiO₂shell thickness was found to play an important role in the SPA mechanism by hindering the heat Outflow, thus decreasing the heating efficiency. It is concluded that a compromise between good heating efficiency and surface functionality for biomedical purposes can be attained by making the SiO₂functional coating as thin as possible., Ministerio de Ciencia e Innovación (MICINN), Comunidad de Madrid, Diputación General de Aragón, Spanish MEC through the Ramon y Cajal program, Depto. de Física de Materiales, Fac. de Ciencias Físicas, TRUE, pub

Published
2009

48. Which countries pay more or less for their long term debt? A CART approach || ¿Qué países pagan más o menos por su deuda a largo plazo? Una aproximación a través de la metodología CART

Author

González-Fernández, Marcos and González-Velasco, Carmen

Subjects
long-term yields, sovereign yields, classification trees, decision trees, tipos a largo plazo, rendimientos soberanos, árboles de clasificación, árboles de decisión, Applied mathematics. Quantitative methods, T57-57.97, Mathematics, QA1-939, Business, HF5001-6182
Abstract

The objective of this paper is to classify a group of EMU countries according to the main determinants of long-term sovereign bond yields. We apply the Classification and Regression Tree method (CART). According to the findings, countries with lower inflation, a lower debt to GDP ratio, a lower average income tax rate, higher public debt maturity and higher IPI growth are placed in classification groups that have lower bond yields. These results confirm the hypothesis that countries with better macroeconomic and fiscal indicators have lower sovereign bond yields.|| El objetivo de este artículo es clasificar un grupo de países de la UME teniendo en cuenta los principales determinantes de los tipos a largo plazo de la deuda soberana. Se aplica la metodología basada en árboles de decisión. Según los resultados, los grupos de países que tienen menor inflación, deuda pública, tipo impositivo medio y mayor vencimiento de la deuda pública y crecimiento económico pagan menos por su deuda soberana a largo plazo. Se confirma la hipótesis de que los países que tienen los mejores indicadores macroeconómicos y fiscales son los que presentan menores costes en su deuda soberana.

Published
2016

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