Search

Your search keyword '"Gong, Shiyi"' showing total 22 results
Start Over Author "Gong, Shiyi"
22 results on '"Gong, Shiyi"'

5. Research Progress of Efficacy Biomarkers Related to Immune Checkpoint Inhibitors

Author

YANG Wenwen, TIAN Hongwei, LEI Caining, HUANG Xianbin, JING Wutang, JIN Chuanwei, SONG Shaoming, GONG Shiyi, and GUO Tiankang

Subjects
immunotherapy, immune checkpoint inhibitors, biomarkers, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

In recent years, immunotherapy with immune checkpoint as the target has made revolutionary breakthroughs in the treatment of a variety of advanced solid tumors. Notwithstanding the impressive long-term therapeutic benefits, their efficacy is limited to a small subset of cancer patients. Some patients experienced drug resistance and immune-related adverse events (irAEs). Immune checkpoint inhibitors (ICIs) primarily include antibodies targeting CTLA-4 and antibodies targeting PD-1 and its ligands. Thus, it is of utmost importance to screen potential biomarkers in populations that may benefit from immunotherapy, to maximize therapeutic benefits. This review summarizes the mechanism of ICIs and its related efficacy biomarker, to better guide the application of immunotherapy in clinical practice.

Published
2022
Full Text
View/download PDF

11. Clinical efficacy and safety of robot assisted surgery for choledochal cysts excisions: a systematic review and meta-analysis

Author

Li, Xiong, primary, Su, Yunan, additional, Tian, Hongwei, additional, Lu, Tingting, additional, Gong, Shiyi, additional, Miao, Changfeng, additional, Song, Shaoming, additional, Lei, Ting, additional, Tan, Yangyang, additional, Xu, Yongcheng, additional, Huang, Xianbin, additional, Yang, Kehu, additional, and Guo, Tiankang, additional

Published
2022
Full Text
View/download PDF

22. Investigation of the sources and seasonal variations of secondary organic aerosols in PM2.5 in Shanghai with organic tracers.

Author

Feng, Jialiang, Li, Man, Zhang, Pan, Gong, Shiyi, Zhong, Mian, Wu, Minghong, Zheng, Mei, Chen, Changhong, Wang, Hongli, and Lou, Shengrong

Subjects
*ATMOSPHERIC aerosols, *PARTICULATE matter, *ORGANIC compounds & the environment, *AUTUMN, *ATMOSPHERIC models, *BIOMASS burning
Abstract

Abstract: One hundred and forty seasonal PM2.5 samples were collected from January 2010 to January 2011 at one urban site and one suburban site simultaneously in a Chinese megacity, Shanghai, to study the concentrations and seasonal variation of secondary organic aerosols (SOA). Concentrations of water-soluble organic carbon (WSOC) were determined together with organic and elemental carbons. Thirteen organic tracers, including the tracer for biomass burning and tracers for SOA from isoprene, α-pinene, β-caryophyllene and toluene, were measured. EC-based method, WSOC-based method, tracer-based method and PMF modeling were used to estimate the seasonal contributions of secondary organic carbon (SOC) in Shanghai, and the results from the different methods were compared and evaluated. Biomass burning was the major contributor to the measured WSOC in the autumn sampling period, while SOA was the major contributor in the other seasons. The concentrations of the SOA tracers in summer were obviously higher than that in other seasons. It was found that SOC estimated with the tracer-based method accounted for only a small part of the SOC from the WSOC-based method in Shanghai, especially for the winter and spring sampling periods. PMF results showed that a large part of the SOC was associated with sulfate and nitrate but not with the SOA tracers. [Copyright &y& Elsevier]

Published
2013
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results