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168 results on '"Gondim, Katia C."'

3. Comparative characterisation of an ecto‐5′‐nucleotidase (CD73) in non‐tumoral MCF10‐A breast cells and triple‐negative MDA‐MB‐231 breast cancer cells.

Author

Rocha‐Vieira, Thais Cristino, Lacerda‐Abreu, Marco Antonio, Carvalho‐Kelly, Luiz Fernando, Santos‐Araújo, Samara, Gondim, Katia C., and Meyer‐Fernandes, José Roberto

Subjects
ADENOSINE monophosphate, ADENINE nucleotides, BREAST cancer, CANCER cells, BIOCHEMICAL substrates
Abstract

Ecto‐5′‐nucleotidase (CD73) hydrolyses 5′AMP to adenosine and inorganic phosphate. Breast cancer cells (MDA‐MB‐231) express high CD73 levels, and this enzyme has been found to play a tumour‐promoting role in breast cancer. However, no studies have sought to investigate whether CD73 has differential affinity or substrate preferences between noncancerous and cancerous breast cells. In the present study, we aimed to biochemically characterise ecto‐5′‐nucleotidase in breast cancer cell lines and assess whether its catalytic function and tumour progression are correlated in breast cancer cells. The results showed that compared to nontumoral breast MCF‐10A cells, triple‐negative breast cancer MDA‐MB‐231 cells had a higher ecto‐5′‐nucleotidase expression level and enzymatic activity. Although ecto‐5′‐nucleotidase activity in the MDA‐MB‐231 cell line showed no selectivity among monophosphorylated substrates, 5′AMP was preferred by the MCF‐10A cell line. Compared to the MCF‐10A cell line, the MDA‐MB‐231 cell line has better hydrolytic ability, lower substrate affinity, and high inhibitory potential after treatment with a specific CD73 inhibitor α,β‑methylene ADP (APCP). Therefore, we demonstrated that a specific inhibitor of the ecto‐5‐nucleotidase significantly reduced the migratory and invasive capacity of MDA‐MB‐231 cells, suggesting that ecto‐5‐nucleotidase activity might play an important role in metastatic progression. [ABSTRACT FROM AUTHOR]

Published
2024
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4. Metabolic remodeling in arthropod embryonic cells under starvation

Author

Nogueira, Cintia Lopes, primary, Arcanjo, Angélica F., additional, Lima, Maria Elisa, additional, Moraes, Bruno, additional, Silva, Renato Martins da, additional, Gondim, Katia C., additional, Konnai, Satoru, additional, Santos, Samara, additional, Filardy, Alessandra D'Almeida, additional, Pinto, Kamila Guimarães, additional, Junior, Itabajara Silva Vaz, additional, and Logullo, Carlos, additional

Published
2024
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5. In the fed state, autophagy plays a crucial role in assisting the insect vector Rhodnius prolixus mobilize TAG reserves under forced flight activity.

Author

Santos-Araujo, Samara, Gomes, Fabio, Carvalho-Kelly, Luiz Fernando, Roberto Meyer-Fernandes, José, Gondim, Katia C., and Ramos, Isabela

Subjects
RHODNIUS prolixus, AUTOPHAGY, UNFOLDED protein response, CHAGAS' disease, DISEASE vectors
Abstract

Autophagy is a cellular degradation pathway mediated by highly conserved autophagy-related genes (Atgs). In our previous work, we showed that inhibiting autophagy under starvation conditions leads to significant physiological changes in the insect vector of Chagas disease Rhodnius prolixus; these changes include triacylglycerol (TAG) retention in the fat body, reduced survival and impaired locomotion and flight capabilities. Herein, because it is known that autophagy can be modulated in response to various stimuli, we further investigated the role of autophagy in the fed state, following blood feeding. Interestingly, the primary indicator for the presence of autophagosomes, the lipidated form of Atg8 (Atg8-II), displayed 20%-50% higher autophagic activation in the first 2 weeks after feeding compared to the third week when digestion was complete. Despite the elevated detection of autophagosomes, RNAi-mediated suppression of RpAtg6 and RpAtg8 did not cause substantial changes in TAG or protein levels in the fat body or the flight muscle during blood digestion. We also found that knockdown of RpAtg6 and RpAtg8 led to modest modulations in the gene expression of essential enzymes involved in lipid metabolism and did not significantly stimulate the expression of the chaperones BiP and PDI, which are the main effectors of the unfolded protein response. These findings indicate that impaired autophagy leads to slight disturbances in lipid metabolism and general cell proteostasis. However, the ability of insects to fly during forced flight until exhaustion was reduced by 60% after knockdown of RpAtg6 and RpAtg8. This change was accompanied by TAG and protein increases as well as decreased ATP levels in the fat body and flight muscle, indicating that autophagy during digestion, i.e., under fed conditions, is necessary to sustain high-performance activity. [ABSTRACT FROM AUTHOR]

Published
2024
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6. Aedes fluviatilis cell lines as new tools to study metabolic and immune interactions in mosquito-Wolbachia symbiosis

Author

Conceição, Christiano Calixto, da Silva, Jhenifer Nascimento, Arcanjo, Angélica, Nogueira, Cíntia Lopes, de Abreu, Leonardo Araujo, de Oliveira, Pedro Lagerblad, Gondim, Katia C., Moraes, Bruno, de Carvalho, Stephanie Serafim, da Silva, Renato Martins, da Silva Vaz, Jr., Itabajara, Moreira, Luciano Andrade, and Logullo, Carlos

Published
2021
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10. Genome of Rhodnius prolixus, an insect vector of Chagas disease, reveals unique adaptations to hematophagy and parasite infection

Author

Mesquita, Rafael D., Vionette-Amaral, Raquel J., Lowenberger, Carl, Rivera-Pomar, Rolando, Monteiro, Fernando A., Minx, Patrick, Spieth, John, Carvalho, A. Bernardo, Panzera, Francisco, Lawson, Daniel, Torres, André Q., Ribeiro, Jose M. C., Sorgine, Marcos H. F., Waterhouse, Robert M., Montague, Michael J., Abad-Franch, Fernando, Alves-Bezerra, Michele, Amaral, Laurence R., Araujo, Helena M., Araujo, Ricardo N., Aravind, L., Atella, Georgia C., Azambuja, Patricia, Berni, Mateus, Bittencourt-Cunha, Paula R., Braz, Gloria R. C., Calderón-Fernández, Gustavo, Carareto, Claudia M. A., Christensen, Mikkel B., Costa, Igor R., Costa, Samara G., Dansa, Marilvia, Daumas-Filho, Carlos R. O., De-Paula, Iron F., Dias, Felipe A., Dimopoulos, George, Emrich, Scott J., Esponda-Behrens, Natalia, Fampa, Patricia, Fernandez-Medina, Rita D., da Fonseca, Rodrigo N., Fontenele, Marcio, Fronick, Catrina, Fulton, Lucinda A., Gandara, Ana Caroline, Garcia, Eloi S., Genta, Fernando A., Giraldo-Calderón, Gloria I., Gomes, Bruno, Gondim, Katia C., Granzotto, Adriana, Guarneri, Alessandra A., Guigó, Roderic, Harry, Myriam, Hughes, Daniel S. T., Jablonka, Willy, Jacquin-Joly, Emmanuelle, Juárez, M. Patricia, Koerich, Leonardo B., Lange, Angela B., Latorre-Estivalis, José Manuel, Lavore, Andrés, Lawrence, Gena G., Lazoski, Cristiano, Lazzari, Claudio R., Lopes, Raphael R., Lorenzo, Marcelo G., Lugon, Magda D., Majerowicz, David, Marcet, Paula L., Mariotti, Marco, Masuda, Hatisaburo, Megy, Karine, Melo, Ana C. A., Missirlis, Fanis, Mota, Theo, Noriega, Fernando G., Nouzova, Marcela, Nunes, Rodrigo D., Oliveira, Raquel L. L., Oliveira-Silveira, Gilbert, Ons, Sheila, Orchard, Ian, Pagola, Lucia, Paiva-Silva, Gabriela O., Pascual, Agustina, Pavan, Marcio G., Pedrini, Nicolás, Peixoto, Alexandre A., Pereira, Marcos H., Pike, Andrew, Polycarpo, Carla, Prosdocimi, Francisco, Ribeiro-Rodrigues, Rodrigo, Robertson, Hugh M., Salerno, Ana Paula, Salmon, Didier, Santesmasses, Didac, Schama, Renata, Seabra-Junior, Eloy S., Silva-Cardoso, Livia, Silva-Neto, Mario A. C., Souza-Gomes, Matheus, Sterkel, Marcos, Taracena, Mabel L., Tojo, Marta, Tu, Zhijian Jake, Tubio, Jose M. C., Ursic-Bedoya, Raul, Venancio, Thiago M., Walter-Nuno, Ana Beatriz, Wilson, Derek, Warren, Wesley C., Wilson, Richard K., Huebner, Erwin, Dotson, Ellen M., and Oliveira, Pedro L.

Published
2015

11. Silencing of the 20S proteasomal subunit-α6 triggers full oogenesis arrest and increased mRNA levels of the selective autophagy adaptor protein p62/SQSTM1 in the ovary of the vector Rhodnius prolixus.

Author

Faria-Reis, Allana, Santos-Araújo, Samara, Pereira, Jéssica, Rios, Thamara, Majerowicz, David, Gondim, Katia C., and Ramos, Isabela

Subjects
RHODNIUS prolixus, PESTICIDE resistance, ADAPTOR proteins, OOGENESIS, INSECT reproduction
Abstract

The high reproductive rates of insects contribute significantly to their ability to act as vectors of a variety of vector-borne diseases. Therefore, it is strategically critical to find molecular targets with biotechnological potential through the functional study of genes essential for insect reproduction. The ubiquitin-proteasome system is a vital degradative pathway that contributes to the maintenance of regular eukaryotic cell proteostasis. This mechanism involves the action of enzymes to covalently link ubiquitin to proteins that are meant to be delivered to the 26S proteasome and broken down. The 26S proteasome is a large protease complex (including the 20S and 19S subcomplexes) that binds, deubiquitylates, unfolds, and degrades its substrates. Here, we used bioinformatics to identify the genes that encode the seven α and β subunits of the 20S proteasome in the genome of R. prolixus and learned that those transcripts are accumulated into mature oocytes. To access proteasome function during oogenesis, we conducted RNAi functional tests employing one of the 20S proteasome subunits (Prosα6) as a tool to suppress 20S proteasomal activity. We found that Prosα6 silencing resulted in no changes in TAG buildup in the fat body and unaffected availability of yolk proteins in the hemolymph of vitellogenic females. Despite this, the silencing of Prosα6 culminated in the impairment of oocyte maturation at the early stages of oogenesis. Overall, we discovered that proteasome activity is especially important for the signals that initiate oogenesis in R. prolixus and discuss in what manner further investigations on the regulation of proteasome assembly and activity might contribute to the unraveling of oogenesis molecular mechanisms and oocyte maturation in this vector. Author summary: In underdeveloped nations, the high frequency of neglected vector-borne illnesses like Chagas disease imposes significant health and financial burdens. Throughout history, the major efficient management strategies for such illnesses have relied on vector population control and continue to do so now. Although early efforts to understand the biology of specific vectors led to significant advances in the creation of management strategies for vector-borne diseases, studies regarding the intricate physiology of local vector species were hindered by the growing use of insecticide-based tools. Currently, the necessity to rely on in-depth species-specific vector biology has been highlighted once again by the growing threat of pesticide resistance and climate change (which can expand endemic areas). Disrupting molecular processes or attacking the metabolic targets required to generate viable eggs is one method of managing vector populations. Here, we present discoveries regarding the molecular basis of oogenesis of the insect vector of Chagas Disease Rhodnius prolixus. We found that proteasome activity is important for the unfolding of the oogenesis program, being essential for the reproductive success of this vector. [ABSTRACT FROM AUTHOR]

Published
2023
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12. Silencing of Mitochondrial Trifunctional Protein A Subunit (HADHA) Increases Lipid Stores, and Reduces Oviposition and Flight Capacity in the Vector Insect Rhodnius prolixus

Author

Arêdes, Daniela S., De Paula, Iron F., Santos-Araujo, Samara, and Gondim, Katia C.

Subjects
General Materials Science
Abstract

Rhodnius prolixus is an obligatory hematophagous insect, vector of Chagas disease. After blood meal, lipids are absorbed, metabolized, synthesized, and accumulated in the fat body. When necessary, stored lipids are mobilized, transported to other organs, or are oxidized to provide energy. Mitochondrial β-oxidation is a cyclic conserved pathway, where degradation of long-chain fatty acids occurs to contribute to cellular energetic demands. Three of its reactions are catalyzed by the mitochondrial trifunctional protein (MTP), which is composed by hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunits alpha and beta (HADHA and HADHB, respectively). Here, we investigated the role of HADHA in lipid metabolism and reproduction of Rhodnius prolixus females. The expression of HADHA gene (RhoprHadha) was determined in the organs of starving adult insects. The flight muscle and ovary had higher expression levels when compared to the anterior and posterior midguts or the fat body. RhoprHadha gene expression was upregulated by blood meal in the flight muscle and fat body. We generated insects with RNAi-mediated knockdown of RhoprHadha to address the physiological role of this gene. RhoprHadha deficiency resulted in higher triacylglycerol content and larger lipid droplets in the fat body during starvation. After feeding, lifespan of the knockdown females was not affected, but they exhibited a decrease in oviposition, although hatching was the same in both groups. Silenced females showed lower forced flight capacity than the control ones, and their fat bodies had lower gene expression levels of Brummer lipase (RhoprBmm) and long-chain acyl-CoA synthetase 2 (RhoprAcsl2). Taken together, these findings indicate that HADHA is important to guarantee successful reproduction and efficient mobilization of lipid stores during starvation and flight.

Published
2022

15. Aedes Fluviatilis Cell Lines As New Tools To Study Metabolic And Immune Interactions In Mosquito-Wolbachia Symbiosis

Author

Conceição, Christiano Calixto, primary, Silva, Jhenifer Nascimento da, additional, Arcanjo, Angélica, additional, Nogueira, Cíntia Lopes, additional, de Abreu, Leonardo Araujo, additional, de Oliveira, Pedro Lagerblad, additional, Gondim, Katia C., additional, Moraes, Bruno, additional, de Carvalho, Stephanie Serafim, additional, Silva, Renato Martins da, additional, Vaz, Itabajara da Silva, additional, Moreira, Luciano Andrade, additional, and Logullo, Carlos, additional

Published
2021
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23. Role of phospholipids in the protein stability of an insect lipoprotein, lipophorin from Rhodnius prolixus

Author

Maya-Monteiro, Clarissa, Oliveira, Pedro L., Gondim, Katia C., Masuda, Hatisaburo, and Ferreira, Sergio T.

Subjects
Lipoproteins -- Research, Biochemistry -- Research, Biological sciences, Chemistry
Abstract

Lipophorin, the major lipoprotein in insect hemolymph, was dephospholidated and structural stability studies were conducted. Findings indicated that phospholipids are not essential for lipophorin stability. Their presence in lipophorin also causes structural instability in aqueous environments. Dephospholidated lipophorin may have additional protein-protein and protein-neutral lipid interactions which enhance structural stability.

Published
1997

25. Erratum to :'Genome of Rhodnius prolixus, an insect vector of Chagas disease, reveals unique adaptations to hematophagy and parasite infection' (vol 112, pg 14936, 2015)

Author

Lowenberger, Carl, Rivera Pomar, Rolando, Monteiro, Fernando A., Minx, Patrick, Spieth, John, Bernardo Carvalho, A., Panzera, Francisco, Lawson, Daniel, Torres, Andre Q., Ribeiro, Jose M. C., Sorgine, Marcos H. F., Waterhouse, Robert M., Montague, Michael J., Abad Franch, Fernando, Alves Bezerra, Michele, Amaral, Laurence R., Araujo, Helena M., Araujo, Ricardo N., Aravind, L., Atella, Georgia C., Azambuja, Patricia, Berni, Mateus, Bittencourt Cunha, Paula R., Braz, Gloria R. C., Calderon Fernandez, Gustavo, Carareto, Claudia M. A., Christensen, Mikkel B., Costa, Igor R., Costa, Samara G., Dansa, Marilvia, Daumas Filho, Carlos R. O., De Paula, Iron F., Dias, Felipe A., Dimopoulos, George, Emrich, Scott J., Esponda Behrens, Natalia, Fampa, Patricia, Fernandez Medina, Rita D., da Fonseca, Rodrigo N., Fontenele, Marcio, Fronick, Catrina, Fulton, Lucinda A., Gandara, Ana Caroline, Garcia, Eloi S., Genta, Fernando A., Giraldo Calderón, Gloria I., Gomes, Bruno, Gondim, Katia C., Granzotto, Adriana, Guarneri, Alessandra A., Guigó, Roderic, Harry, Myriam, Hughes, Daniel S. T., Jablonka, Willy, Jacquin Joly, Emmanuelle, Patricia Juarez, M., Koerich, Leonardo B., Latorre Estivalis, Jose Manuel, Lavore, Andrés, Lawrence, Gena G., Lazoski, Cristiano, Lazzari, Claudio R., Lopes, Raphael R., Lorenzo, Marcelo G., Lugon, Magda D., Majerowicz, David, Marcet, Paula L., Mariotti, Marco, Masuda, Hatisaburo, Megy, Karine, Melo, Ana C.A., Missirlis, Fanis, Mota, Theo, Noriega, Fernando G., Nouzova, Marcela, Nunes, Rodrigo D., Oliveira, Raquel L.L., Oliveira Silveira, Gilbert, Ons, Sheila, Pagola, Lucia, Paiva Silva, Gabriela O., Pascual, Agustina, Pavan, Marcio G., Pedrini, Nicolas, Peixoto, Alexandre A., Pereira, Marcos H., Pike, Andrew, Polycarpo, Carla, Prosdocimi, Francisco, Ribeiro Rodrigues, Rodrigo, Robertson, Hugh M., Salerno, Ana Paula, Salmon, Didier, Santesmasses, Didac, Schama, Renata, Seabra Junior, Eloy S., Silva Cardoso, Livia, Mesquita, Rafael D., and Vionette Amaral, Raquel J.

Subjects
rhodnius prolixus, Rhodnius prolixus, genome, hematophagy, immunity, Chagas disease, maladie de chagas
Abstract

Rhodnius prolixus not only has served as a model organism for the study of insect physiology, but also is a major vector of Chagas disease, an illness that affects approximately seven million people worldwide. We sequenced the genome of R. prolixus, generated assembled sequences covering 95% of the genome (similar to 702 Mb), including 15,456 putative protein-coding genes, and completed comprehensive genomic analyses of this obligate blood-feeding insect. Although immune-deficiency (IMD)-mediated immune responses were observed, R. prolixus putatively lacks key components of the IMD pathway, suggesting a reorganization of the canonical immune signaling network. Although both Toll and IMD effectors controlled intestinal microbiota, neither affected Trypanosoma cruzi, the causal agent of Chagas disease, implying the existence of evasion or tolerance mechanisms. R. prolixus has experienced an extensive loss of selenoprotein genes, with its repertoire reduced to only two proteins, one of which is a selenocysteine-based glutathione peroxidase, the first found in insects. The genome contained actively transcribed, horizontally transferred genes from Wolbachia sp., which showed evidence of codon use evolution toward the insect use pattern. Comparative protein analyses revealed many lineage-specific expansions and putative gene absences in R. prolixus, including tandem expansions of genes related to chemoreception, feeding, and digestion that possibly contributed to the evolution of a blood-feeding lifestyle. The genome assembly and these associated analyses provide critical information on the physiology and evolution of this important vector species and should be instrumental for the development of innovative disease control methods.

Published
2016

29. Epithelial Mesenchymal Transition Induces Aberrant Glycosylation through Hexosamine Biosynthetic Pathway Activation

Author

Lucena, Miguel C., primary, Carvalho-Cruz, Patricia, additional, Donadio, Joana L., additional, Oliveira, Isadora A., additional, de Queiroz, Rafaela M., additional, Marinho-Carvalho, Monica M., additional, Sola-Penna, Mauro, additional, de Paula, Iron F., additional, Gondim, Katia C., additional, McComb, Mark E., additional, Costello, Catherine E., additional, Whelan, Stephen A., additional, Todeschini, Adriane R., additional, and Dias, Wagner B., additional

Published
2016
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33. An insight into the transcriptome of the digestive tract of the bloodsucking bug, Rhodnius prolixus.

Author

Ribeiro, Servio Pontes, Genta, Fernando A, Sorgine, Marcos H F, Logullo, Raquel, Mesquita, Maria, Paiva-Silva, Gabriela O, Majerowicz, David, Medeiros, Marcelo, Koerich, Leonardo, Terra, JL., Ferreira, Clélia, Pimentel, André C, Bisch, Paulo Mascarello, Leite, Daniel C, Diniz, Michelle M P, da S G V Junior, João Lídio, Da Silva, Manuela L, Araujo, Ricardo N, Gandara, Ana Caroline P, Brosson, Sébastien, Salmon, Didier, Bousbata, Sabrina, González-Caballero, Natalia, Silber, Ariel Mariano, Alves-Bezerra, Michele, Gondim, Katia C, Silva-Neto, Mário Alberto C, Atella, Georgia C, Araujo, Helena, Dias, Felipe A, Polycarpo, Carla, Vionette-Amaral, Raquel J, Fampa, Patrícia, Melo, Ana Claudia A, Tanaka, Aparecida S, Balczun, Carsten, Oliveira, José Henrique M, Gonçalves, Renata L S, Lazoski, Cristiano, Rivera-Pomar, Rolando, Diambra, Luis, Schaub, Günter A, Garcia, Elói S, Azambuja, Patrícia, Braz, Glória R C, Oliveira, Pedro L, Ribeiro, Servio Pontes, Genta, Fernando A, Sorgine, Marcos H F, Logullo, Raquel, Mesquita, Maria, Paiva-Silva, Gabriela O, Majerowicz, David, Medeiros, Marcelo, Koerich, Leonardo, Terra, JL., Ferreira, Clélia, Pimentel, André C, Bisch, Paulo Mascarello, Leite, Daniel C, Diniz, Michelle M P, da S G V Junior, João Lídio, Da Silva, Manuela L, Araujo, Ricardo N, Gandara, Ana Caroline P, Brosson, Sébastien, Salmon, Didier, Bousbata, Sabrina, González-Caballero, Natalia, Silber, Ariel Mariano, Alves-Bezerra, Michele, Gondim, Katia C, Silva-Neto, Mário Alberto C, Atella, Georgia C, Araujo, Helena, Dias, Felipe A, Polycarpo, Carla, Vionette-Amaral, Raquel J, Fampa, Patrícia, Melo, Ana Claudia A, Tanaka, Aparecida S, Balczun, Carsten, Oliveira, José Henrique M, Gonçalves, Renata L S, Lazoski, Cristiano, Rivera-Pomar, Rolando, Diambra, Luis, Schaub, Günter A, Garcia, Elói S, Azambuja, Patrícia, Braz, Glória R C, and Oliveira, Pedro L

Abstract

The bloodsucking hemipteran Rhodnius prolixus is a vector of Chagas' disease, which affects 7-8 million people today in Latin America. In contrast to other hematophagous insects, the triatomine gut is compartmentalized into three segments that perform different functions during blood digestion. Here we report analysis of transcriptomes for each of the segments using pyrosequencing technology. Comparison of transcript frequency in digestive libraries with a whole-body library was used to evaluate expression levels. All classes of digestive enzymes were highly expressed, with a predominance of cysteine and aspartic proteinases, the latter showing a significant expansion through gene duplication. Although no protein digestion is known to occur in the anterior midgut (AM), protease transcripts were found, suggesting secretion as pro-enzymes, being possibly activated in the posterior midgut (PM). As expected, genes related to cytoskeleton, protein synthesis apparatus, protein traffic, and secretion were abundantly transcribed. Despite the absence of a chitinous peritrophic membrane in hemipterans - which have instead a lipidic perimicrovillar membrane lining over midgut epithelia - several gut-specific peritrophin transcripts were found, suggesting that these proteins perform functions other than being a structural component of the peritrophic membrane. Among immunity-related transcripts, while lysozymes and lectins were the most highly expressed, several genes belonging to the Toll pathway - found at low levels in the gut of most insects - were identified, contrasting with a low abundance of transcripts from IMD and STAT pathways. Analysis of transcripts related to lipid metabolism indicates that lipids play multiple roles, being a major energy source, a substrate for perimicrovillar membrane formation, and a source for hydrocarbons possibly to produce the wax layer of the hindgut. Transcripts related to amino acid metabolism showed an unanticipated priority for degrada, Journal Article, Research Support, N.I.H. Intramural, Research Support, Non-U.S. Gov't, SCOPUS: ar.j, SCOPUS: ar.j, info:eu-repo/semantics/published

Published
2014

36. An Insight into the Transcriptome of the Digestive Tract of the Bloodsucking Bug, Rhodnius prolixus

Author

Ribeiro, José M. C., primary, Genta, Fernando A., additional, Sorgine, Marcos H. F., additional, Logullo, Raquel, additional, Mesquita, Rafael D., additional, Paiva-Silva, Gabriela O., additional, Majerowicz, David, additional, Medeiros, Marcelo, additional, Koerich, Leonardo, additional, Terra, Walter R., additional, Ferreira, Clélia, additional, Pimentel, André C., additional, Bisch, Paulo M., additional, Leite, Daniel C., additional, Diniz, Michelle M. P., additional, Junior, João Lídio da S. G. V., additional, Da Silva, Manuela L., additional, Araujo, Ricardo N., additional, Gandara, Ana Caroline P., additional, Brosson, Sébastien, additional, Salmon, Didier, additional, Bousbata, Sabrina, additional, González-Caballero, Natalia, additional, Silber, Ariel Mariano, additional, Alves-Bezerra, Michele, additional, Gondim, Katia C., additional, Silva-Neto, Mário Alberto C., additional, Atella, Georgia C., additional, Araujo, Helena, additional, Dias, Felipe A., additional, Polycarpo, Carla, additional, Vionette-Amaral, Raquel J., additional, Fampa, Patrícia, additional, Melo, Ana Claudia A., additional, Tanaka, Aparecida S., additional, Balczun, Carsten, additional, Oliveira, José Henrique M., additional, Gonçalves, Renata L. S., additional, Lazoski, Cristiano, additional, Rivera-Pomar, Rolando, additional, Diambra, Luis, additional, Schaub, Günter A., additional, Garcia, Elói S., additional, Azambuja, Patrícia, additional, Braz, Glória R. C., additional, and Oliveira, Pedro L., additional

Published
2014
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38. Trypanosoma cruzi: Effects of heat shock on ecto-ATPase activity

Author

Giarola, Naira Lígia Lima, primary, de Almeida-Amaral, Elmo Eduardo, additional, Collopy-Júnior, Itallo, additional, Fonseca-de-Souza, André Luiz, additional, Majerowicz, David, additional, Paes, Lisvane Silva, additional, Gondim, Katia C., additional, and Meyer-Fernandes, José Roberto, additional

Published
2013
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42. LDL uptake by Leishmania amazonensis: Involvement of membrane lipid microdomains

Author

De Cicco, Nuccia N.T., primary, Pereira, Miria G., additional, Corrêa, José R., additional, Andrade-Neto, Valter V., additional, Saraiva, Felipe B., additional, Chagas-Lima, Alessandra C., additional, Gondim, Katia C., additional, Torres-Santos, Eduardo C., additional, Folly, Evelize, additional, Saraiva, Elvira M., additional, Cunha-e-Silva, Narcisa L., additional, Soares, Maurilio J., additional, and Atella, Georgia C., additional

Published
2012
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