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Your search keyword '"Gomez-Martínez R"' showing total 18 results
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18 results on '"Gomez-Martínez R"'

4. 698P Outcomes of patients with testicular germ cell tumors in Latin-America

Author

Campos Gomez, S., Lyra-Gonzalez, I., Sobrevilla-Moreno, N., Bourlon de los Rios, M.T., Ramírez Fallas, R.A., Diaz Alvarado, M.G., Enríquez Aceves, M-I., Saenz Frias, J.A., Macias Diaz, S., Arreguin Gonzalez, F.E., Richter, L., Gomez-Martinez, R., Lopez-Facundo, N.A., Gonzales Nogales, J.E., Ortiz-de la O, E.F., Morales-Peralta, A., Reyes-Lopez, A., Ramos Ramirez, M., Mandujano-Romero, A., and Vera-Badillo, F.E.

Published
2024
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14. Huntington's disease-comorbidity

Author

Ortega Garcia, M., Marti Garnica, V., Martinez Martinez, C., Blanco del Valle, P., Gómez Martinez, R., Garcia Acebes, P., Garcia Marin, S., and Franch Pato, C.

Published
2016
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18. Is the ancillary chemotherapy approach of any value in the treatment of infratentorial primitive neuroectodermal tumors with surgery and radiotherapy?

Author

Rivera-Luna R, Gomez-Martínez R, Leal-Leal C, Cardenas-Cardos R, Castellanos-Toledo A, Rueda-Franco F, Marx-Bracho A, and Lanche-Guevara T

Subjects
Adolescent, Adult, Antineoplastic Agents administration & dosage, Antineoplastic Agents therapeutic use, Antineoplastic Agents, Phytogenic administration & dosage, Antineoplastic Agents, Phytogenic therapeutic use, Cerebellar Neoplasms pathology, Child, Child, Preschool, Cisplatin administration & dosage, Cisplatin therapeutic use, Combined Modality Therapy, Etoposide adverse effects, Etoposide therapeutic use, Female, Humans, Infant, Male, Neoplasm Staging, Neuroectodermal Tumors, Primitive, Peripheral pathology, Retrospective Studies, Survival Analysis, Treatment Outcome, Antineoplastic Combined Chemotherapy Protocols therapeutic use, Cerebellar Neoplasms radiotherapy, Cerebellar Neoplasms surgery, Neuroectodermal Tumors, Primitive, Peripheral radiotherapy, Neuroectodermal Tumors, Primitive, Peripheral surgery
Abstract

A retrospective historical analysis of patients under 18 years of age with the histopathological diagnosis of infratentorial primitive neuroectodermal tumor (PNET) is presented. The survey embraced two different groups of children. Group 1 was defined as those patients treated from 1972 to 1984 with surgical resection plus neuraxis radiotherapy alone. Group 2 was made up of children treated from 1990 to 1996 with the same approach but with the addition of adjuvant chemotherapy: cisplatin (day 1) and etoposide (days 1-3) every 3 weeks for 6 months. Group 1 embraced 42 children with an age range of 1-16 years (mean 6 years, SD 4.4 years). In group 2 there were 34 children, their ages ranging from 1 to 18 years (mean 7.2, SD 4.6 years). The prevalence of stages T2M0 and T3M0 was similar in both groups, but in group 1 there were 4 patients (9.5%) whose spinal fluid was positive for tumor cells (M1), while in group 2 there were 7 children (20.5%) with positive spinal fluid. There was an unequivocal initial response to treatment in 86% of these children in group 1 and in 79% in group 2. The event-free survival (EFS) was 30% at 252 months in group 1, while for group 2 the EFS was 67.6% at 63 months (P 0.002). Mortality from tumor activity was noted in 26 patients (70%) in group 1, while in group 2 mortality attributable to tumor progression was documented in 11 children (32%). We conclude that the use of adjuvant chemotherapy in these patients improves survival without any significant morbidity.

Published
1998
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