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2. Oral Hypoxia-Inducible Factor 2α Inhibitor Belzutifan in Ocular von Hippel-Lindau Disease: Subgroup Analysis of the Single-Arm Phase 2 LITESPARK-004 Study

Author

Welsh, Sarah, Thavikulwat, Alisa T., Keenan, Tiarnan D.L., Bellur, Sunil, Mac, Lisa, Cukras, Catherine A., Wiley, Henry E., Srinivasan, Ramaprasad, Maranchie, Jodi K., Chhablani, Jay, Iversen, Ane Bundsbæk Bøndergaard, Kruse, Anders, Jonasch, Eric, Gombos, Dan S., Else, Tobias, Demirci, Hakan, Maughan, Benjamin L., Hartnett, M. Elizabeth, Coleman, Hanna R., Fu, Wei, Perini, Rodolfo F., Liu, Yanfang, Linehan, W. Marston, and Chew, Emily Y.

Published
2024
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5. Head and neck surgical oncology in the time of a pandemic: Subsite‐specific triage guidelines during the COVID‐19 pandemic

Author

Consortium, Anderson Head and Neck Surgery Treatment Guidelines, members:, Consortium, Maniakas, Anastasios, Jozaghi, Yelda, Zafereo, Mark E, Sturgis, Erich M, Su, Shirley Y, Gillenwater, Ann M, Gidley, Paul W, Lewis, Carol M, Diaz, Eduardo, Goepfert, Ryan P, Kupferman, Michael E, Gross, Neil D, Hessel, Amy C, Pytynia, Kristen B, Nader, Marc‐Elie, Wang, Jennifer R, Lango, Miriam N, Kiong, Kimberley L, Guo, Theresa, Zhao, Xiao, Yao, Christopher MKL, Appelbaum, Eric, Alpard, Jennifer, Garcia, Jose A, Terry, Shawn, Flynn, Jill E, Bauer, Sarah, Fournier, Danielle, Burgess, Courtlyn G, Wideman, Cayla, Johnston, Matthew, You, Chenxi, De Luna, Rolando, Joseph, Liza, Diersing, Julia, Prescott, Kaitlin, Heiberger, Katherine, Mugartegui, Lilian, Rodriguez, Jessica, Zendehdel, Sara, Sellers, Justin, Friddell, Rebekah A, Thomas, Ajay, Khanjae, Sonam J, Schwarzlose, Katherine B, Chambers, Mark S, Hofstede, Theresa M, Cardoso, Richard C, Wesson, Ruth Aponte, Won, Alex, Otun, Adegbenga O, Gombos, Dan S, Al‐Zubidi, Nagham, Hutcheson, Katherine A, Gunn, G Brandon, Rosenthal, David I, Gillison, Maura L, Ferrarotto, Renata, Weber, Randal S, Hanna, Ehab Y, Myers, Jeffrey N, and Lai, Stephen Y

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Patient Safety, Dental/Oral and Craniofacial Disease, Clinical Research, Rare Diseases, Prevention, Cancer, Good Health and Well Being, Betacoronavirus, COVID-19, Cancer Care Facilities, Communicable Disease Control, Consensus, Coronavirus Infections, Female, Head and Neck Neoplasms, Humans, Male, Occupational Health, Outcome Assessment, Health Care, Pandemics, Patient Selection, Pneumonia, Viral, Practice Guidelines as Topic, SARS-CoV-2, Surgical Oncology, Triage, United States, oncology, otolaryngology, MD Anderson Head and Neck Surgery Treatment Guidelines Consortium, Consortium members, Dentistry, Otorhinolaryngology, Clinical sciences
Abstract

BackgroundCOVID-19 pandemic has strained human and material resources around the world. Practices in surgical oncology had to change in response to these resource limitations, triaging based on acuity, expected oncologic outcomes, availability of supportive resources, and safety of health care personnel.MethodsThe MD Anderson Head and Neck Surgery Treatment Guidelines Consortium devised the following to provide guidance on triaging head and neck cancer (HNC) surgeries based on multidisciplinary consensus. HNC subsites considered included aerodigestive tract mucosa, sinonasal, salivary, endocrine, cutaneous, and ocular.RecommendationsEach subsite is presented separately with disease-specific recommendations. Options for alternative treatment modalities are provided if surgical treatment needs to be deferred.ConclusionThese guidelines are intended to help clinicians caring for patients with HNC appropriately allocate resources during a health care crisis, such as the COVID-19 pandemic. We continue to advocate for individual consideration of cases in a multidisciplinary fashion based on individual patient circumstances and resource availability.

Published
2020

6. Head and neck surgical oncology in the time of a pandemic: Subsite-specific triage guidelines during the COVID-19 pandemic.

Author

MD Anderson Head and Neck Surgery Treatment Guidelines Consortium, Consortium members, Maniakas, Anastasios, Jozaghi, Yelda, Zafereo, Mark E, Sturgis, Erich M, Su, Shirley Y, Gillenwater, Ann M, Gidley, Paul W, Lewis, Carol M, Diaz, Eduardo, Goepfert, Ryan P, Kupferman, Michael E, Gross, Neil D, Hessel, Amy C, Pytynia, Kristen B, Nader, Marc-Elie, Wang, Jennifer R, Lango, Miriam N, Kiong, Kimberley L, Guo, Theresa, Zhao, Xiao, Yao, Christopher MKL, Appelbaum, Eric, Alpard, Jennifer, Garcia, Jose A, Terry, Shawn, Flynn, Jill E, Bauer, Sarah, Fournier, Danielle, Burgess, Courtlyn G, Wideman, Cayla, Johnston, Matthew, You, Chenxi, De Luna, Rolando, Joseph, Liza, Diersing, Julia, Prescott, Kaitlin, Heiberger, Katherine, Mugartegui, Lilian, Rodriguez, Jessica, Zendehdel, Sara, Sellers, Justin, Friddell, Rebekah A, Thomas, Ajay, Khanjae, Sonam J, Schwarzlose, Katherine B, Chambers, Mark S, Hofstede, Theresa M, Cardoso, Richard C, Wesson, Ruth Aponte, Won, Alex, Otun, Adegbenga O, Gombos, Dan S, Al-Zubidi, Nagham, Hutcheson, Katherine A, Gunn, G Brandon, Rosenthal, David I, Gillison, Maura L, Ferrarotto, Renata, Weber, Randal S, Hanna, Ehab Y, Myers, Jeffrey N, and Lai, Stephen Y

Subjects
MD Anderson Head and Neck Surgery Treatment Guidelines Consortium, Consortium members, Humans, Pneumonia, Viral, Coronavirus Infections, Head and Neck Neoplasms, Consensus, Communicable Disease Control, Patient Selection, Occupational Health, Cancer Care Facilities, Triage, United States, Female, Male, Practice Guidelines as Topic, Pandemics, Patient Safety, Surgical Oncology, Betacoronavirus, Outcome Assessment, Health Care, COVID-19, SARS-CoV-2, oncology, otolaryngology, Outcome Assessment, Health Care, Pneumonia, Viral, Otorhinolaryngology, Clinical Sciences, Dentistry
Abstract

BackgroundCOVID-19 pandemic has strained human and material resources around the world. Practices in surgical oncology had to change in response to these resource limitations, triaging based on acuity, expected oncologic outcomes, availability of supportive resources, and safety of health care personnel.MethodsThe MD Anderson Head and Neck Surgery Treatment Guidelines Consortium devised the following to provide guidance on triaging head and neck cancer (HNC) surgeries based on multidisciplinary consensus. HNC subsites considered included aerodigestive tract mucosa, sinonasal, salivary, endocrine, cutaneous, and ocular.RecommendationsEach subsite is presented separately with disease-specific recommendations. Options for alternative treatment modalities are provided if surgical treatment needs to be deferred.ConclusionThese guidelines are intended to help clinicians caring for patients with HNC appropriately allocate resources during a health care crisis, such as the COVID-19 pandemic. We continue to advocate for individual consideration of cases in a multidisciplinary fashion based on individual patient circumstances and resource availability.

Published
2020

7. Current Management of Retinoblastoma

Author

Ebrahimi, Katayoon B., Hang, Abraham, O’Brien, Joan M., O’Brien, Joan Marie, Section editor, Gragoudas, Evangelos S., Section editor, Gombos, Dan S., Section editor, Aronow, Mary E., Section editor, Albert, Daniel M., editor, Miller, Joan W., editor, Azar, Dimitri T., editor, and Young, Lucy H., editor

Published
2022
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8. Current Treatment of Conjunctival Malignancies

Author

O’Neil, E., Lee, V., O’Brien, Joan M., O’Brien, Joan Marie, Section editor, Gragoudas, Evangelos S., Section editor, Gombos, Dan S., Section editor, Aronow, Mary E., Section editor, Albert, Daniel M., editor, Miller, Joan W., editor, Azar, Dimitri T., editor, and Young, Lucy H., editor

Published
2022
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9. Assessment of Risk for Hereditary Retinoblastoma

Author

Ganguly, Arupa, Niazi, Rojeen, Ryan, Elyse, O’Brien, Joan Marie, Section editor, Gragoudas, Evangelos S., Section editor, Gombos, Dan S., Section editor, Aronow, Mary E., Section editor, Albert, Daniel M., editor, Miller, Joan W., editor, Azar, Dimitri T., editor, and Young, Lucy H., editor

Published
2022
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10. Staging and Grouping of Retinoblastoma

Author

Berry, Jesse L., O’Brien, Joan Marie, Section editor, Gragoudas, Evangelos S., Section editor, Gombos, Dan S., Section editor, Aronow, Mary E., Section editor, Albert, Daniel M., editor, Miller, Joan W., editor, Azar, Dimitri T., editor, and Young, Lucy H., editor

Published
2022
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13. The Phakomatoses

Author

Yordi, Sari, Binkley, Elaine M., Traboulsi, Elias I., Singh, Arun D., O’Brien, Joan Marie, Section editor, Gragoudas, Evangelos S., Section editor, Gombos, Dan S., Section editor, Aronow, Mary E., Section editor, Albert, Daniel M., editor, Miller, Joan W., editor, Azar, Dimitri T., editor, and Young, Lucy H., editor

Published
2022
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14. Choroidal Osteoma

Author

Shields, Carol L., Shields, Jerry A., O’Brien, Joan Marie, Section editor, Gragoudas, Evangelos S., Section editor, Gombos, Dan S., Section editor, Aronow, Mary E., Section editor, Albert, Daniel M., editor, Miller, Joan W., editor, Azar, Dimitri T., editor, and Young, Lucy H., editor

Published
2022
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15. Choroidal Nevus and Melanocytoma

Author

Alhumaid, Sulaiman, Harbour, J. William, O’Brien, Joan Marie, Section editor, Gragoudas, Evangelos S., Section editor, Gombos, Dan S., Section editor, Aronow, Mary E., Section editor, Albert, Daniel M., editor, Miller, Joan W., editor, Azar, Dimitri T., editor, and Young, Lucy H., editor

Published
2022
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16. Choroidal Hemangiomas

Author

Aronow, Mary E., Gragoudas, Evangelos S., O’Brien, Joan Marie, Section editor, Gombos, Dan S., Section editor, Albert, Daniel M., editor, Miller, Joan W., editor, Azar, Dimitri T., editor, and Young, Lucy H., editor

Published
2022
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17. Leukemias

Author

Binkley, Elaine M., Schachat, Andrew P., O’Brien, Joan Marie, Section editor, Gragoudas, Evangelos S., Section editor, Gombos, Dan S., Section editor, Aronow, Mary E., Section editor, Albert, Daniel M., editor, Miller, Joan W., editor, Azar, Dimitri T., editor, and Young, Lucy H., editor

Published
2022
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18. Uveal Melanoma: Genetics and Clinical Prognostication

Author

Visconte, Valeria, Singh, Nakul, Singh, Arun D., O’Brien, Joan Marie, Section editor, Gragoudas, Evangelos S., Section editor, Gombos, Dan S., Section editor, Aronow, Mary E., Section editor, Albert, Daniel M., editor, Miller, Joan W., editor, Azar, Dimitri T., editor, and Young, Lucy H., editor

Published
2022
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21. Ophthalmoplegia Associated With Extramedullary Multiple Myeloma: Case Series From a Tertiary Cancer Center.

Author

Dhanani, Ujalashah, Mortensen, Peter W., Raviskanthan, Subahari, Lee, Andrew G., Whyte, Andrew T., Gombos, Dan S., and Al-Zubidi, Nagham

Abstract

Background: Multiple myeloma (MM) is a malignant disorder of plasma cells that results in tumor cells replacing the bone marrow. In extramedullary MM (EMM), however, tumor cells proliferate outside the bone marrow. EMM may produce ophthalmoplegia through direct invasion of the superior orbital fissure, cavernous sinus, and/or sphenoidal sinus. Several mechanisms have been proposed including cranial nerve palsies, direct infiltration of bone, extraocular muscle metastasis, myelomatous meningitis, and parenchymal or paraneoplastic effects. Methods: We retrospectively reviewed the medical records of 7 patients at MD Anderson Cancer Center who suffered from ophthalmoplegia secondary to extramedullary MM between 2019 and 2021. We collected information regarding the symptoms, signs, radiographic and laboratory findings, management, complications, and prognosis of these patients throughout their disease course. Results: Skull base MRI revealed 4 patients with ophthalmoplegias secondary to superior orbital fissure invasion, 2 patients with ophthalmoplegias secondary to cavernous sinus invasion, and 1 patient with ophthalmoplegia secondary to sphenoid sinus invasion. Conclusions: This is a case series describing 7 patients with ophthalmoplegias secondary to EMM. Our article is unique because of the size of the included cohort, which is large when compared with most English language publications detailing such ophthalmoplegias. [ABSTRACT FROM AUTHOR]

Published
2024
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23. Phase I Trial of Definitive Concurrent Chemoradiotherapy and Trametinib for KRAS-Mutated Non-Small Cell Lung Cancer

Author

Lin, Steven H, Lin, Heather Y, Verma, Vivek, Xu-Welliver, Meng, Thall, Peter F, Yao, Luyang, Kim, Peter Y, Gombos, Dan S, Kawedia, Jitesh D, Komaki, Ritsuko, Gomez, Daniel R, Nguyen, Quynh-Nhu, O'Reilly, Michael S, Lu, Charles, Fossella, Frank V, Skoulidis, Ferdinandos, Zhang, Jianjun, Tsao, Anne S, Heymach, John V, and Blumenschein, George R

Published
2022
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24. Immune-Related Oral, Otologic, and Ocular Adverse Events

Author

Al-Zubidi, Nagham, Page, J. Cody, Gombos, Dan S., Srivastava, Akanksha, Appelbaum, Eric, Gidley, Paul W., Chambers, Mark S., Nader, Marc-Elie, Crusio, Wim E., Series Editor, Dong, Haidong, Series Editor, Radeke, Heinfried H., Series Editor, Rezaei, Nima, Series Editor, Steinlein, Ortrud, Series Editor, Xiao, Junjie, Series Editor, Naing, Aung, editor, and Hajjar, Joud, editor

Published
2021
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25. Oral HIF-2α Inhibitor Belzutifan in Ocular von Hippel-Lindau Disease: Subgroup Analysis of the Single-Arm Phase 2 LITESPARK-004 Study

Author

Wiley, Henry E., primary, Srinivasan, Ramaprasad, additional, Maranchie, Jodi K., additional, Chhablani, Jay, additional, Bøndergaard Iversen, Ane Bundsbæk, additional, Kruse, Anders, additional, Jonasch, Eric, additional, Gombos, Dan S., additional, Else, Tobias, additional, Demirci, Hakan, additional, Maughan, Benjamin L., additional, Hartnett, M. Elizabeth, additional, Coleman, Hanna R., additional, Fu, Wei, additional, Perini, Rodolfo F., additional, Liu, Yanfang, additional, Linehan, W. Marston, additional, Chew, Emily Y., additional, Bøndergaard Iversen Anders Kruse, Ane Bundsbæk, additional, Welsh, Sarah, additional, Gombos, Daniel S., additional, Wiley, Henry, additional, Thavikulwat, Alisa T., additional, Keenan, Tiarnan D.L., additional, Bellur, Sunil, additional, Mac, Lisa, additional, Cukras, Catherine A., additional, Hartnett, Mary Elizabeth, additional, and Hakan Demirci, Tobias Else, additional

Published
2024
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26. Immune-Related Oral, Otologic, and Ocular Adverse Events

Author

Srivastava, Akanksha, Al-Zubidi, Nagham, Appelbaum, Eric, Gombos, Dan S., Nader, Marc-Elie, Gidley, Paul W., Chambers, Mark S., Crusio, Wim E., Series Editor, Lambris, John D., Series Editor, Radeke, Heinfried H., Series Editor, Rezaei, Nima, Series Editor, Naing, Aung, editor, and Hajjar, Joud, editor

Published
2020
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