275 results on '"Goldsmith, Elizabeth J."'
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2. Functional divergence caused by mutations in an energetic hotspot in ERK2
3. Enzymes | With No Lysine Kinases
4. Water and chloride as allosteric inhibitors in WNK kinase osmosensing
5. Yersinia YopJ Acetylates and Inhibits Kinase Activation by Blocking Phosphorylation
6. Water and chloride as allosteric inhibitors in WNK kinase osmosensing
7. Hydrostatic Pressure Sensing by WNK kinases
8. Changes in Protein Conformational Mobility upon Activation of Extracellular Regulated Protein Kinase-2 as Detected by Hydrogen Exchange
9. Supplementary Figures from WNK1 Enhances Migration and Invasion in Breast Cancer Models
10. The Structure of Mitogen-Activated Protein Kinase p38 at 2.1- angstrom Resolution
11. Identification of a Class of WNK Isoform-Specific Inhibitors Through High-Throughput Screening
12. Intracellular Ion Control of WNK Signaling
13. Identification of a Class of WNK Isoform-Specific Inhibitors Through High-Throughput Screening
14. Synthesis and Structural Characterization of Novel Trihalo-sulfone Inhibitors of WNK1
15. MAP Kinase Modules: The Excursion Model and the Steps that Count
16. WNK1 collaborates with TGF-β in endothelial cell junction turnover and angiogenesis
17. Abstract LB506: Structure based small molecule drug design for targeting WNK1 in triple negative breast cancer
18. Nuclear speckle integrity and function require TAO2 kinase
19. Structural Basis for the Activation of Glycogen Phosphorylase b by Adenosine Monophosphate
20. Amino Acid Residues that Affect Interaction of Tissue-Type Plasminogen Activator with Plasminogen Activator Inhibitor 1
21. Crystallization and Preliminary X-Ray Diffraction Analysis of P450 terp and the Hemoprotein Domain of P450 BM-3 , Enzymes Belonging to Two Distinct Classes of the Cytochrome P450 Superfamily
22. Osmosensing by WNK Kinases
23. WNK1 Enhances Migration and Invasion in Breast Cancer Models
24. WNKs are potassium-sensitive kinases
25. Substrate and docking interactions in serine/threonine protein kinases
26. Multiple active site conformations revealed by distant site mutation in ornithine decarboxylase
27. Structural Studies of MAP Kinase Cascade Components
28. A Phosphorylated Intermediate in the Activation of WNK Kinases
29. Altering the reaction specificity of eukaryotic ornithine decarboxylase
30. X-ray structure of ornithine decarboxylase from Trypanosoma brucei: the native structure and the structure in complex with alpha-difluoromethylornithine
31. Crystal structure of domain-swapped STE20 OSR1 kinase domain
32. Activation mechanism of the MAP kinase ERK2 by dual phosphorylation
33. Kinetically controlled folding of the serpin plasminogen activator inhibitor 1
34. Mutation of position 52 in ERK2 creates a nonproductive binding mode for adenosine 5'-triphosphate
35. Converting Tissue Plasminogen Activator to a Zymogen: A Regulatory Triad of Asp-His-Ser
36. Atomic structure of the MAP kinase ERK2 at 2.3 angstrom resolution
37. Structural basis of latency in plasminogen activator inhibitor-1
38. Inhibitors of WNK1
39. Discovery of novel TAOK2 inhibitor scaffolds from high-throughput screening
40. A pressure sensing protein kinase
41. Water structure in the intracellular osmosensor WNK1
42. Intracellular Chloride and Scaffold Protein Mo25 Cooperatively Regulate Transepithelial Ion Transport through WNK Signaling in the Malpighian Tubule
43. X-ray structure of Paramecium bursaria chlorella virus arginine decarboxylase: Insight into the structural basis for substrate specificity
44. How activating mutations affect MEK1 regulation and function
45. Binding of nonphysiological protein and peptide substrates to proteases: differences between urokinase-type plasminogen activator and trypsin and contributions to the evolution of regulated proteolysis
46. Dimerization in MAP-kinase signaling
47. Domain-Swapping Switch Point in Ste20 Protein Kinase SPAK
48. Evolution of Substrate Specificity within a Diverse Family of β/α-Barrel-fold Basic Amino Acid Decarboxylases: X-RAY STRUCTURE DETERMINATION OF ENZYMES WITH SPECIFICITY FOR l-ARGININE AND CARBOXYNORSPERMIDINE*
49. Structure of MAPKs
50. Chloride Sensing by WNK1 Involves Inhibition of Autophosphorylation
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