561 results on '"Gold DR"'
Search Results
2. Differences in incidence and persistence of atopic dermatitis by race/ethnicity
- Author
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Blomberg, M, Rifas-Shiman, SL, Camargo, CA Jr, Gold, DR, Thyssen, JP, Litonjua, AA, Gillman, MW, Asgari, MM, and Oken, E
- Abstract
BackgroundMost studies on racial disparities in childhood atopic dermatitis (AD) did not consider persistent AD or account for differences in vitamin D status.MethodsAmong 1418 children recruited from a Massachusetts HMO into the pre-birth Project Viva cohort, we examined associations of child’s race/ethnicity with maternal report of child’s AD diagnosis by annual questionnaires. We used multivariable logistic regression adjusted for socio- demographics (maternal education, household income, smoking exposure, parental atopy, breastfeeding duration, child sex) and cord blood 25-hydroxyvitamin D, to estimate odds ratios (OR) of incident AD by early childhood (median age 3.3 years), and, among young children with AD, OR of persistence through mid-childhood (median age 7.7 years).Results68% of children were non-Hispanic white, 13% were black, and 19% were other race/ethnicities. By early childhood, 497/1418 (35%) had incident AD. Among those with both AD and follow- up to mid-childhood, 58/389 (15%) had persistent AD. Black children were more likely than white children to have incident AD (OR 2.21; 95% CI 1.60, 3.04), even after adjustment for socio-demographics (2.64; 1.79, 3.89) and vitamin D levels (1.93; 1.07, 3.48). Black children also had higher odds of persistent AD (3.21; 1.63, 6.32; fully adjusted 4.60; 1.24, 17.13). Children with other race/ethnicities had non-significantly higher risk for AD incidence and persistence than white children.ConclusionIn this cohort, compared with white children, black children and children with other race/ethnicities were at higher risk for incident and persistent AD, even after accounting for differences in socio-demographic characteristics and vitamin D levels.
- Published
- 2016
3. Association of Exposure to Ambient Air Pollution With Thyroid Function During Pregnancy
- Author
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Ghassabian, A, Pierotti, L, Basterrechea, M, Chatzi, L, Estarlich, M, Fernandez-Somoano, A, Fleisch, AF, Gold, DR, Julvez, J, Karakosta, P, Lertxundi, A, Lopez-Espinosa, MJ, Mulder, Tessa, Korevaar, Tim, Oken, E, Peeters, Robin, Rifas-Shiman, S, Stephanou, E, Tardon, A, Tiemeier, Henning, Vrijheid, M, Vrijkotte, TG, Sunyer, J, Guxens Junyent, Monica, Ghassabian, A, Pierotti, L, Basterrechea, M, Chatzi, L, Estarlich, M, Fernandez-Somoano, A, Fleisch, AF, Gold, DR, Julvez, J, Karakosta, P, Lertxundi, A, Lopez-Espinosa, MJ, Mulder, Tessa, Korevaar, Tim, Oken, E, Peeters, Robin, Rifas-Shiman, S, Stephanou, E, Tardon, A, Tiemeier, Henning, Vrijheid, M, Vrijkotte, TG, Sunyer, J, and Guxens Junyent, Monica
- Published
- 2019
4. A time for every purpose under heaven.
- Author
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Gold, Dr. Mark and Simon, Hiam
- Subjects
HEAVEN ,SUNRISE & sunset - Published
- 2023
5. Netanyahu's assault on democracy hits a speed bump.
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Gold, Dr. Mark and Simon, Hiam
- Subjects
LEGAL professions ,SPEED bumps ,WOMEN'S rights ,VOLUNTEER service ,POLITICAL attitudes ,LAW enforcement - Abstract
But the most extreme elements of Netanyahu's extremist coalition were too committed to their vision of an Israel unrestrained by the rule of law. The plans for the assault on Israel's democracy were created in the United States by a right-wing think tank, the Kohelet Policy Forum, formed and operated by Moshe Koppel, an American immigrant to Israel. This new government coalition, formed with the slimmest of majorities, is only three months old and has announced plans not simply to revise the judicial system but to cripple it, removing the teeth from the watchdog that protects Israel's democracy -- the Supreme Court. [Extracted from the article]
- Published
- 2023
6. War is not healthy for children and other living things.
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Gold, Dr. Mark and Simon, Hiam
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WAR ,PRISONERS of war ,GOVERNMENT policy ,ARAB-Israeli conflict ,PALESTINIAN refugees ,HUNGER strikes ,CIVILIANS in war - Abstract
The article discusses the ongoing war between Israel and Hamas in Gaza. It highlights the challenges faced by Israel in achieving its goals of destroying Hamas and ensuring the safety of its citizens, as Hamas has built an infrastructure of tunnels and bunkers and uses civilian areas as cover. The article also criticizes statements made by Israeli government officials that promote violence and the suffering of Gaza's civilian population. It suggests that a ceasefire and diplomatic efforts with Arab states could be a more effective approach to achieving long-term peace and stability in the region. [Extracted from the article]
- Published
- 2024
7. MESSENGER Mission to Mercury
- Author
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Gold, Dr. Robert
- Abstract
Biography - Robert Gold is the chief technologist for the Space Department at the Johns Hopkins University Applied Physics Laboratory (APL) in Laurel, MD. He is a physicist who has specialized in heliospheric and planetary particles and fields research. Dr. Gold is the science payload manager for the MESSENGER mission, which includes the first spacecraft to orbit the planet Mercury. He held the same role for the Near Earth Asteroid Rendezvous (NEAR) mission, the first to orbit and land on an asteroid. He served as the APL project scientist for NASA’s Advanced Composition Explorer (ACE) mission, which provides early warning of interplanetary disturbances before they hit Earth. Dr. Gold conceived the Ilion mission concept to rendezvous and land on a Jovian Trojan asteroid, with a spacecraft that uses Advanced Stirling Radioisotope Generators for power. He has written more than 75 scientific publications and asteroid 4955 Gold was named for his work on the NEAR mission.
- Published
- 2011
8. Defense versus revenge.
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Gold, Dr. Mark and Simon, Hiam
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PALESTINIAN citizens of Israel ,REVENGE ,TERRORISM - Abstract
As it conducted operations to clear Hamas terrorists from Israeli territory, the IDF began a bombing campaign and initiated a siege. While Hamas has recruited from Gaza, Gazans aren't Hamas and have no control over its actions. Evacuating civilians supports the mission as Hamas well knows -- it will do all it can to prevent that evacuation, calling for all civilians NOT to move away. [Extracted from the article]
- Published
- 2023
9. Mouse allergen exposure, wheeze and atopy in the first seven years of life
- Author
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Phipatanakul, W, Celedón, JC, Hoffman, EB, Abdulkerim, H, Ryan, LM, and Gold, DR
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Adult ,Male ,Allergy ,Infant ,Dust ,Allergens ,Dermatitis, Atopic ,Mice ,Air Pollution, Indoor ,Child, Preschool ,Surveys and Questionnaires ,Animals ,Humans ,Female ,Child ,Respiratory Sounds ,Skin Tests ,Follow-Up Studies - Abstract
Background: Little is known about mouse allergen exposure in home environments and the development of wheezing, asthma and atopy in childhood. Objective: To examine the relation between mouse allergen exposure and wheezing, atopy, and asthma in the first 7 years of life. Methods: Prospective study of 498 children with parental history of allergy or asthma followed from birth to age 7 years, with longitudinal questionnaire ascertainment of reported mouse exposure and dust sample mouse urinary protein allergen levels measured at age 2-3 months. Results: Parental report of mouse exposure in the first year of life was associated with increased risk of transient wheeze and wheezing in early life. Current report of mouse exposure was also significantly associated with current wheeze throughout the first 7 years of life in the longitudinal analysis (P = 0.03 for overall relation of current mouse to current wheeze). However, early life mouse exposure did not predict asthma, eczema or allergic rhinitis at age 7 years. Exposure to detectable levels of mouse urinary protein in house dust samples collected at age 2-3 months was associated with a twofold increase in the odds of atopy (sensitization to >=1 allergen) at school age (95% confidence interval for odds ratio = 1.1-3.7; P = 0.03 in a multivariate analysis. Conclusions: Among children with parental history of asthma or allergies, current mouse exposure is associated with increased risk of wheeze during the first 7 years of life. Early mouse exposure was associated with early wheeze and atopy later in life. © 2008 The Authors.
- Published
- 2008
10. Variation in total and specific IgE: Effects of ethnicity and socioeconomic status
- Author
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Litonjua, AA, Celedón, JC, Hausmann, J, Nikolov, M, Sredl, D, Ryan, L, Platts-Mills, TAE, Weiss, ST, and Gold, DR
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Adult ,Allergy ,Social Class ,Hypersensitivity ,Prevalence ,Humans ,Ethnic Groups ,Female ,Immunoglobulin E - Abstract
Background: Asthma is common in minority and disadvantaged populations, whereas atopic disorders other than asthma appear to be less prevalent. It is unclear whether the same holds true for objective markers of sensitization. Objective: To determine the association of asthma, atopic disorders, and specific sensitization with race and socioeconomic factors. Methods: We analyzed total and specific IgE among 882 women (577 white, 169 black, and 136 Hispanic) who delivered a child at a large tertiary hospital in Boston, Mass, and who were screened for participation in a family and birth cohort study. Race/ethnicity and other characteristics were obtained from screening questionnaires. Addresses were geocoded, and 3 census-based geographic area socioeconomic variables were derived from block group information from the 1990 US Census. Results: Black and Hispanic women were more likely to come from areas with low socioeconomic indicators and were more likely to have asthma than white women. However, these women were less likely to have hay fever and eczema than their white counterparts. Compared with white women, black women had higher mean total IgE levels; had greater proportions of sensitization to indoor, outdoor, and fungal allergens; and were more than twice as likely to be sensitized to ≥3 aeroallergens. Conclusion: The racial/ethnic disparities in atopic disorders may represent either underdiagnosis or underreporting and suggest that allergy testing may be underused in some populations. Differences in total IgE levels and specific allergen sensitization are likely a result of the complex interplay between exposures associated with socioeconomic disadvantage. © 2005 American Academy of Allergy, Asthma and Immunology.
- Published
- 2005
11. Bottle feeding in the bed or crib before sleep time and wheezing in early childhood
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Celedon, Jc, Litonjua, Aa, Louise Ryan, Weiss, St, and Gold, Dr
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Male ,Time Factors ,Infant Equipment ,Infant ,Comorbidity ,Immunoglobulin E ,Pediatrics ,Risk Assessment ,Cohort Studies ,Cross-Sectional Studies ,Breast Feeding ,Recurrence ,Population Surveillance ,Child, Preschool ,Multivariate Analysis ,Gastroesophageal Reflux ,Confidence Intervals ,Humans ,Infant Food ,Female ,Longitudinal Studies ,Prospective Studies ,Sleep ,Respiratory Sounds ,Follow-Up Studies - Abstract
OBJECTIVE: Bottle feeding in the bed or crib before sleep time has been associated with an increased risk of wheezing in the first year of life. We examined whether bottle feeding in the bed or crib before sleep time in the first year of life is associated with wheezing in the first 5 years of life. METHODS: In a prospective cohort study of 448 children with parental history of atopy followed from birth, we examined the relation between the number of bimonthly parental reports of bottle feeding in the bed or crib before sleep time in the first year of life (range: 0-6 reports) and parental report of wheezing in the first 5 years of life. Additional outcome measures included recurrent wheezing (> or =2 episodes of wheezing in the previous year) and asthma (physician-diagnosed asthma and > or =1 episode of wheezing in the previous year) at the age of 5 years. RESULTS: The risk of recurrent wheezing and asthma at 5 years of age increased significantly with each additional report of bottle feeding in the bed or crib before sleep time in the first year of life. The risk of wheezing between the ages of 1 and 5 years increased with each additional report of bottle feeding in the bed or crib before sleep time in the first year of life. As an example, a child whose parents reported bottle feeding in the bed or crib before sleep time on 3 occasions in the first year of life had 1.5 times higher risk of wheezing between the ages of 1 and 5 years than a child whose parents did not report bottle feeding in the bed or crib before sleep time in the first year of life (95% confidence interval for relative risk: 1.12-2.12). CONCLUSIONS: Among children with parental history of atopy, bottle feeding in the bed or crib before sleep time in the first year of life is a risk factor for recurrent wheezing and asthma at 5 years of age and a risk factor for wheezing between the ages of 1 and 5 years.
- Published
- 2002
12. A longitudinal analysis of wheezing in young children: The independent effects of early life exposure to house dust endotoxin, allergens, and pets
- Author
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Litonjua, AA, Milton, DK, Celedon, JC, Ryan, L, Weiss, ST, and Gold, DR
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Male ,Time Factors ,Allergy ,Infant ,Dust ,Environmental Exposure ,Allergens ,Asthma ,respiratory tract diseases ,Endotoxins ,Dogs ,Animals, Domestic ,Air Pollution, Indoor ,Child, Preschool ,Cats ,Animals ,Humans ,Female ,Longitudinal Studies ,Respiratory Sounds - Abstract
Background: It has been postulated that exposure to bacterial endotoxins and animals early in life might confer protection against the development of asthma and allergies. Objective: We investigated the longitudinal effects of exposure to house dust endotoxin (HDE), allergen levels, and the presence of a dog in the home on wheezing in young children over a 4-year period. Methods: Two hundred twenty-six children younger than 5 years were followed for 4 years. Endotoxin and allergen levels were measured from house dust collected at baseline. Longitudinal associations were investigated by using a proportional hazards technique that allowed for multiple outcomes per subject. Results: Exposure to high concentrations of HDE of greater than the median level was associated with an increased risk for wheezing over the period of observation (multivariate relative risk, 1.52; 95% CI, 1.07-2.14), but this risk rapidly decreased over time (P for trend = .005). Exposure to cockroach allergen was associated with increased risk for wheezing, whereas exposure to cat allergen and the presence of a dog in the home were both associated with decreased risk for wheezing. The risks associated with cockroach allergen, cat allergen, and dog did not change over the period of observation. Conclusion: The negative associations between exposures to dogs and cat allergen and wheeze appear to be independent of the effects of endotoxin and suggest that separate mechanisms might mediate the effects of HDE exposure and pet exposure on the developing immune system.
- Published
- 2002
13. Exposure assessment in cohort studies of childhood asthma
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Arrandale, VH, Brauer, M, Brook, JR, Brunekreef, B, Gold, DR, London, SJ, Miller, JD, Özkaynak, H, Ries, NM, Sears, MR, Silverman, FS, Takaro, TK, Arrandale, VH, Brauer, M, Brook, JR, Brunekreef, B, Gold, DR, London, SJ, Miller, JD, Özkaynak, H, Ries, NM, Sears, MR, Silverman, FS, and Takaro, TK
- Abstract
Background: The environment is suspected to play an important role in the development of childhood asthma. Cohort studies are a powerful observational design for studying exposure-response relationships, but their power depends in part upon the accuracy of the exposure assessment. Objective: The purpose of this paper is to summarize and discuss issues that make accurate exposure assessment a challenge and to suggest strategies for improving exposure assessment in longitudinal cohort studies of childhood asthma and allergies. Data synthesis: Exposures of interest need to be prioritized, because a single study cannot measure all potentially relevant exposures. Hypotheses need to be based on proposed mechanisms, critical time windows for effects, prior knowledge of physical, physiologic, and immunologic development, as well as genetic pathways potentially influenced by the exposures. Modifiable exposures are most important from the public health perspective. Given the interest in evaluating gene environment interactions, large cohort sizes are required, and planning for data pooling across independent studies is critical. Collection of additional samples, possibly through subject participation, will permit secondary analyses. Models combining air quality, environmental, and dose data provide exposure estimates across large cohorts but can still be improved. Conclusions: Exposure is best characterized through a combination of information sources. Improving exposure assessment is critical for reducing measurement error and increasing power, which increase confidence in characterization of children at risk, leading to improved health outcomes.
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- 2011
14. Respiratory illnesses in early life and asthma and atopy in childhood
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Ramsey, CD, Gold, DR, Litonjua, AA, Sredl, DL, Ryan, L, Celedón, JC, Ramsey, CD, Gold, DR, Litonjua, AA, Sredl, DL, Ryan, L, and Celedón, JC
- Abstract
Background: The relation between respiratory illnesses in early life and the development of asthma and atopy in childhood is incompletely understood. Objective: We sought to examine the relationship between respiratory illnesses in early life and atopic diseases at school age. Methods: We performed a prospective birth cohort study of the relationship between respiratory illnesses in the first year of life and asthma, atopy (sensitization to ≥1 allergen), and allergic rhinitis at school age in 440 children with a parental history of atopy. Logistic regression was used to examine the relationship between respiratory illnesses and asthma, atopy, and allergic rhinitis. The relationship between respiratory illnesses in early life and repeated measures of wheezing between the ages of 1 and 7 years was investigated by using a proportional hazards models. Results: Physician-diagnosed croup (adjusted odds ratio [OR], 0.30; 95% CI, 0.12-0.72) and having 2 or more physician-diagnosed ear infections (adjusted OR, 0.58; 95% CI, 0.35-0.98) in the first year of life were inversely associated with atopy at school age. Physician-diagnosed bronchiolitis before age 1 year was significantly associated with asthma at age 7 years (adjusted OR, 2.77; 95% CI, 1.23-6.22). Recurrent nasal catarrh (≥3 episodes of a runny nose) in the first year of life was associated with allergic rhinitis at age 7 years (adjusted OR, 2.99; 95% CI, 1.03-8.67). Conclusion: The relationship between early-life respiratory illnesses and asthma and atopy is complex and likely dependent on the type of infection and immune response it initiates. Clinical implications: Certain respiratory illnesses in early life modify the risk of atopy and asthma at school age. © 2007 American Academy of Allergy, Asthma & Immunology.
- Published
- 2007
15. Predictors of cord blood IgE levels in children at risk for asthma and atopy
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Scirica, CV, Gold, DR, Ryan, L, Abulkerim, H, Celedón, JC, Platts-Mills, TAE, Naccara, LM, Weiss, ST, Litonjua, AA, Scirica, CV, Gold, DR, Ryan, L, Abulkerim, H, Celedón, JC, Platts-Mills, TAE, Naccara, LM, Weiss, ST, and Litonjua, AA
- Abstract
Background: Increased cord blood IgE levels, in conjunction with a family history of atopy, are associated with the development of allergic diseases in children. However, little is known about predictors of cord blood IgE levels. Objective: Our objective was to identify predictors of cord blood IgE levels among infants at increased risk of atopy. Methods: Cord blood IgE levels were measured in 874 infants who were screened for participation in a birth cohort. Questionnaires were administered after birth of the infant, and maternal and cord blood was obtained for measurement of IgE levels. Logistic and tobit regression models were used to study the association between perinatal factors and cord blood IgE levels. Results: In multivariable models infant male sex, increased maternal total IgE level, maternal allergen sensitization, Hispanic ethnicity, and residence in low-income areas were associated with detectable or increased cord blood IgE levels, whereas increasing maternal age was associated with undetectable or lower cord blood IgE levels. Although maternal smoking during pregnancy was positively associated with cord blood IgE levels in univariable models, the effect did not persist after adjusting for potential confounders. Conclusion: Maternal allergen sensitization, markers of socioeconomic disadvantage and race/ethnicity, maternal age, and infant sex might influence fetal production of IgE. We found no association of maternal parity, mode of delivery, gestational age, or season of birth with cord blood IgE levels. Clinical implications: The identification of these definable familial and environmental factors that predict cord blood IgE levels might help in the early detection of infants at risk for atopic disorders. © 2007 American Academy of Allergy, Asthma & Immunology.
- Published
- 2007
16. The relationship between ambient air pollution and heart rate variability differs for individuals with heart and pulmonary disease
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Wheeler, A, Zanobetti, A, Gold, DR, Schwartz, J, Stone, P, Suh, HH, Wheeler, A, Zanobetti, A, Gold, DR, Schwartz, J, Stone, P, and Suh, HH
- Abstract
Associations between concentrations of ambient fine particles [particulate matter < 2.5 microm aerodynamic diameter (PM2.5)] and heart rate variability (HRV) have differed by study population. We examined the effects of ambient pollution on HRV for 18 individuals with chronic obstructive pulmonary disease (COPD) and 12 individuals with recent myocardial infarction (MI) living in Atlanta, Georgia. HRV, baseline pulmonary function, and medication data were collected for each participant on 7 days in fall 1999 and/or spring 2000. Hourly ambient pollution concentrations were obtained from monitoring sites in Atlanta. The association between ambient pollution and HRV was examined using linear mixed-effect models. Ambient pollution had opposing effects on HRV in our COPD and MI participants, resulting in no significant effect of ambient pollution on HRV in the entire population for 1-, 4-, or 24-hr moving averages. For individuals with COPD, interquartile range (IQR) increases in 4-hr ambient PM2.5 (11.65 microg/m3)) and nitrogen dioxide (11.97 ppb) were associated with 8.3% [95% confidence interval (CI), 1.7-15.3%] and 7.7% (95% CI, 0.1-15.9%) increase in the SD of normal R-R intervals (SDNN), respectively. For individuals with MI, IQR increases in 4-hr PM2.5 (8.54 microg/m3) and NO2 (9.25 ppb) were associated with a nonsignificant 2.9% (95% CI, -7.8 to 2.3) and significant 12.1 (95% CI, -19.5 to -4.0) decrease in SDNN. Beta-blocker and bronchodilator intake and baseline forced expiratory volume in 1 sec modified the PM-SDNN association significantly, with effects consistent with those by disease group. Results indicate heterogeneity in the autonomic response to air pollution due to differences in baseline health, with significant associations for ambient NO2 suggesting an important role for traffic-related pollution.
- Published
- 2006
17. Fungal levels in the home and allergic rhinitis by 5 years of age
- Author
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Stark, PC, Celedón, JC, Chew, GL, Ryan, LM, Burge, HA, Muilenberg, ML, Gold, DR, Stark, PC, Celedón, JC, Chew, GL, Ryan, LM, Burge, HA, Muilenberg, ML, and Gold, DR
- Abstract
Studies have repeatedly demonstrated that sensitization to fungi, such as Alternaria, is strongly associated with allergic rhinitis and asthma in children. However, the role of exposure to fungi in the development of childhood allergic rhinitis is poorly understood. In a prospective birth cohort of 405 children of asthmatic/allergic parents from metropolitan Boston, Massachusetts, we examined in-home high fungal concentrations (> 90th percentile) measured once within the first 3 months of life as predictors of doctor-diagnosed allergic rhinitis in the first 5 years of life. In multivariate Cox regression analyses, predictors of allergic rhinitis included high levels of dust-borne Aspergillus [hazard ratio (HR) = 3.27; 95% confidence interval (CI), 1.50-7.14], Aureobasidium (HR = 3.04; 95% CI, 1.33-6.93), and yeasts (HR = 2.67; 95% CI, 1.26-5.66). The factors controlled for in these analyses included water damage or mild or mildew in the building during the first year of the child's life, any lower respiratory tract infection in the first year, male sex, African-American race, fall date of birth, and maternal IgE to Alternaria > 0.35 U/mL. Dust-borne Alternaria and nonsporulating and total fungi were also predictors of allergic rhinitis in models excluding other fungi but adjusting for all of the potential confounders listed above. High measured fungal concentrations and reports of water damage, mold, or mildew in homes may predispose children with a family history of asthma or allergy to the development of allergic rhinitis.
- Published
- 2005
18. Within-home versus between-home variability of house dust endotoxin in a birth cohort
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Abraham, JH, Gold, DR, Dockery, DW, Ryan, L, Park, JH, Milton, DK, Abraham, JH, Gold, DR, Dockery, DW, Ryan, L, Park, JH, and Milton, DK
- Abstract
Endotoxin exposure has been proposed as an environmental determinant of allergen responses in children. To better understand the implications of using a single measurement of house dust endotoxin to characterize exposure in the first year of life, we evaluated room-specific within-home and between-home variability in dust endotoxin obtained from 470 households in Boston, Massachusetts. Homes were sampled up to two times over 5-11 months, We analyzed 1,287 dust samples from the kitchen, family room, and baby's bedroom for endotoxin. We fit a mixed-effects model to estimate mean levels and the variation of endotoxin between homes, between rooms, and between sampling times. Endotoxin ranged from 2 to 1,945 units per milligram of dust. Levels were highest during summer and lowest in the winter. Mean endotoxin levels varied significantly from room to room. Cross-sectionally, endotoxin was moderately correlated between family room and bedroom floor (r = 0.30), between family room and kitchen (r = 0.32), and between kitchen and bedroom (r = 0.42). Adjusting for season, the correlation of endotoxin levels within homes over time was 0.65 for both the bedroom and kitchen and 0.54 for the family room. The temporal within-home variance of endotoxin was lowest for bedroom floor samples and highest for kitchen samples. Between-home variance was lowest in the family room and highest for kitchen samples. Adjusting, for season, within-home variation was less than between-home variation for all three rooms. These results suggest that room-to-room and home-to-home differences in endotoxin influence the total variability more than factors affecting endotoxin levels within a room over time.
- Published
- 2005
19. Fungal levels in the home and lower respiratory tract illnesses in the first year of life
- Author
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Stark, PC, Burge, HA, Ryan, LM, Milton, DK, Gold, DR, Stark, PC, Burge, HA, Ryan, LM, Milton, DK, and Gold, DR
- Abstract
The association between home dampness and lower respiratory symptoms in children has been well documented. Whether fungal exposures contribute to this association is uncertain. In a prospective birth cohort of 499 children of parents with asthma/allergies, we examined in-home fungal concentrations as predictors of lower respiratory illnesses (LRI) (croup, pneumonia, bronchitis, and bronchiolitis) in the first year. In multivariate analyses, we found a significant increased relative risk (RR) between LRI and high levels (more than the 90th percentile) of airborne Penicillium (RR = 1.73, 95% confidence interval [CI], 1.23, 2.43), dust-borne Cladosporium (RR = 1.52; CI, 1.02, 2.25), Zygomycetes (RR = 1.96; CI, 1.35, 2.83), and Alternaria (RR = 1.51; CI, 1.00, 2.28), after controlling for sex, presence of water damage or visible mold/mildew, born in winter, breastfeeding, and being exposed to other children through siblings. In a multivariate analysis, the RR of LRI was elevated in households with any fungal level at more than the 90th percentile (RR = 1.86; CI, 1.21, 2.88). Exposure to high fungal levels increased the risk of LRI in infancy, even for infants with nonwheezing LRI. Actual mechanisms remain unknown, but fungi and their components (glucans, mycotoxins, and proteins) may increase the risk of LRI by acting as irritants or through increasing susceptibility to infection.
- Published
- 2003
20. Lack of association between antibiotic use in the first year of life and asthma, allergic rhinitis, or eczema at age 5 years
- Author
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Celedón, JC, Litonjua, AA, Ryan, L, Weiss, ST, Gold, DR, Celedón, JC, Litonjua, AA, Ryan, L, Weiss, ST, and Gold, DR
- Abstract
Five retrospective studies have reported an association between antibiotic use in early life and asthma in childhood. We studied the relationship between the use of oral antibiotics in the first year of life and asthma, allergic rhinitis, and eczema at age 5 years among 448 children with a parental history of atopy monitored from birth. After adjustment for potential confounders, we found no significant association between antibiotic use in the first year of life and asthma (odds ratio [OR] for one versus no courses of antibiotics, 0.5; 95% confidence interval [CI] for OR, 0.2 to 1.5; OR for two or more versus no courses of antibiotics, 1.0; 95% CI for OR, 0.5 to 2.2), recurrent wheezing, allergic rhinitis, or eczema at age 5 years. There was no significant association between antibiotic use in the first year of life and having at least one of three atopic diseases (asthma, allergic rhinitis, or eczema) at age 5 years (OR for one versus no courses of antibiotics, 0.7; 95% CI, 0.4 to 1.4, OR for two or more versus no courses of antibiotics, 0.9; 95% Cl, 0.5 to 1.4). Our findings do not support the hypothesis that antibiotic use in early life is associated with the subsequent development of asthma and atopy in childhood.
- Published
- 2002
21. Exposure to Coarse but Not Fine Concentrated Ambient Particles Increases Airway Leukocytes in Humans.
- Author
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Speck, M, primary, Urch, RB, additional, Fritscher, L, additional, Corey, P, additional, Brook, JR, additional, Gold, DR, additional, and Silverman, F, additional
- Published
- 2009
- Full Text
- View/download PDF
22. Diversity of the Gut Microbiota and Eczema in Infants.
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Forno, E, primary, Onderdonk, AB, additional, McCracken, J, additional, Litonjua, AA, additional, Laskey, D, additional, Delaney, ML, additional, DuBois, AM, additional, Gold, DR, additional, Ryan, LM, additional, Weiss, ST, additional, and Celedon, JC, additional
- Published
- 2009
- Full Text
- View/download PDF
23. Fungal Predictors of Childhood Allergic Rhinitis.
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Behbod, B, primary, Sordillo, JE, additional, Stark, PC, additional, and Gold, DR, additional
- Published
- 2009
- Full Text
- View/download PDF
24. Asthma Prevalence and Current and Past Body Mass Index among Adolescents in Cyprus.
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Behbod, B, primary, Yiallouros, PK, additional, Zeniou, M, additional, Economou, M, additional, Kolokotroni, O, additional, Gold, DR, additional, and Milton, DK, additional
- Published
- 2009
- Full Text
- View/download PDF
25. Heart Rate Variability Associated with Traffic, and Ambient Air Pollution in High-Risk Subjects Following a Cardiac Event.
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Zanobetti, A, primary, Gold, DR, additional, Stone, PH, additional, Suh, HH, additional, Schwartz, J, additional, Coull, BA, additional, and Speizer, FE, additional
- Published
- 2009
- Full Text
- View/download PDF
26. Allergen Exposure, Allergy, and TV Viewing as Predictors of Exhaled NO in Childhood.
- Author
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Sordillo, JE, primary, Milton, DK, additional, and Gold, DR, additional
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- 2009
- Full Text
- View/download PDF
27. Endotoxin exposure in inner-city schools and homes of children with asthma.
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Sheehan WJ, Hoffman EB, Fu C, Baxi SN, Bailey A, King EM, Chapman MD, Lane JP, Gaffin JM, Permaul P, Gold DR, Phipatanakul W, Sheehan, William J, Hoffman, Elaine B, Fu, Chunxia, Baxi, Sachin N, Bailey, Ann, King, Eva-Maria, Chapman, Martin D, and Lane, Jeffrey P
- Published
- 2012
- Full Text
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28. Associations of PM10 with sleep and sleep-disordered breathing in adults from seven U.S. urban areas.
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Zanobetti A, Redline S, Schwartz J, Rosen D, Patel S, O'Connor GT, Lebowitz M, Coull BA, Gold DR, Zanobetti, Antonella, Redline, Susan, Schwartz, Joel, Rosen, Dennis, Patel, Sanjay, O'Connor, George T, Lebowitz, Michael, Coull, Brent A, and Gold, Diane R
- Abstract
Rationale: Sleep-disordered breathing (SDB), the recurrent episodic disruption of normal breathing during sleep, affects as much as 17% of U.S. adults, and may be more prevalent in poor urban environments. SDB and air pollution have been linked to increased cardiovascular diseases and mortality, but the association between pollution and SDB is poorly understood.Objectives: We used data from the Sleep Heart Health Study (SHHS), a U.S. multicenter cohort study assessing cardiovascular and other consequences of SDB, to examine whether particulate air matter less than 10 μm in aerodynamic diameter (PM(10)) was associated with SDB among persons 39 years of age and older.Methods: Using baseline data from SHHS urban sites, outcomes included the following: the respiratory disturbance index (RDI); percentage of sleep time at less than 90% O(2) saturation; and sleep efficiency, measured by overnight in-home polysomnography. We applied a fixed-effect model containing a city effect, controlling for potential predictors. In all models we included both the 365-day moving averages of PM(10) and temperature (long-term effects) and the differences between the daily measures of these two predictors and their 365-day average (short-term effects).Measurements and Main Results: In summer, increases in RDI or percentage of sleep time at less than 90% O(2) saturation, and decreases in sleep efficiency, were all associated with increases in short-term variation in PM(10). Over all seasons, we found that increased RDI was associated with an 11.5% (95% confidence interval: 1.96, 22.01) increase per interquartile range increase (25.5°F) in temperature.Conclusions: Reduction in air pollution exposure may decrease the severity of SDB and nocturnal hypoxemia and may improve cardiac risk. [ABSTRACT FROM AUTHOR]- Published
- 2010
- Full Text
- View/download PDF
29. Wavelet-based functional linear mixed models: an application to measurement error-corrected distributed lag models.
- Author
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Malloy EJ, Morris JS, Adar SD, Suh H, Gold DR, Coull BA, Malloy, Elizabeth J, Morris, Jeffrey S, Adar, Sara D, Suh, Helen, Gold, Diane R, and Coull, Brent A
- Abstract
Frequently, exposure data are measured over time on a grid of discrete values that collectively define a functional observation. In many applications, researchers are interested in using these measurements as covariates to predict a scalar response in a regression setting, with interest focusing on the most biologically relevant time window of exposure. One example is in panel studies of the health effects of particulate matter (PM), where particle levels are measured over time. In such studies, there are many more values of the functional data than observations in the data set so that regularization of the corresponding functional regression coefficient is necessary for estimation. Additional issues in this setting are the possibility of exposure measurement error and the need to incorporate additional potential confounders, such as meteorological or co-pollutant measures, that themselves may have effects that vary over time. To accommodate all these features, we develop wavelet-based linear mixed distributed lag models that incorporate repeated measures of functional data as covariates into a linear mixed model. A Bayesian approach to model fitting uses wavelet shrinkage to regularize functional coefficients. We show that, as long as the exposure error induces fine-scale variability in the functional exposure profile and the distributed lag function representing the exposure effect varies smoothly in time, the model corrects for the exposure measurement error without further adjustment. Both these conditions are likely to hold in the environmental applications we consider. We examine properties of the method using simulations and apply the method to data from a study examining the association between PM, measured as hourly averages for 1-7 days, and markers of acute systemic inflammation. We use the method to fully control for the effects of confounding by other time-varying predictors, such as temperature and co-pollutants. [ABSTRACT FROM AUTHOR]
- Published
- 2010
- Full Text
- View/download PDF
30. Differences in heart rate variability associated with long-term exposure to NO2.
- Author
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Dietrich DF, Gemperli A, Gaspoz J, Schindler C, Liu LS, Gold DR, Schwartz J, Rochat T, Barthélémy J, Pons M, Roche F, Hensch NMP, Bridevaux P, Gerbase MW, Neu U, Ackermann-Liebrich U, and SAPALDIA Team
- Published
- 2008
- Full Text
- View/download PDF
31. Particulate air pollution as a risk factor for ST-segment depression in patients with coronary artery disease.
- Author
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Chuang KJ, Coull BA, Zanobetti A, Suh H, Schwartz J, Stone PH, Litonjua A, Speizer FE, Gold DR, Chuang, Kai Jen, Coull, Brent A, Zanobetti, Antonella, Suh, Helen, Schwartz, Joel, Stone, Peter H, Litonjua, Augusto, Speizer, Frank E, and Gold, Diane R
- Published
- 2008
- Full Text
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32. Increased use of beta-agonists leading to non-ST-segment elevation myocardial infarction in a patient with hemodynamically significant myocardial bridging.
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Gold DR, Zolli JR, Makaryus AN, Gold, Daniel R, Zolli, Janet R, and Makaryus, Amgad N
- Abstract
Myocardial bridging is not uncommon. However, hemodynamic instability in the setting of myocardial bridging is rare. We describe an unusual case of a 47-year-old woman whose increased use of inhaled albuterol led to a non-ST-segment elevation myocardial infarction and unmasking of hemodynamically significant myocardial bridging. We detail its diagnosis through myocardial perfusion imaging and coronary angiography. To our knowledge, this is the first time previously undiagnosed myocardial bridging has led to a myocardial infarction in the setting of inhaled albuterol use. [ABSTRACT FROM AUTHOR]
- Published
- 2008
33. Air pollution and inflammation in type 2 diabetes: a mechanism for susceptibility.
- Author
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O'Neill MS, Veves A, Sarnat JA, Zanobetti A, Gold DR, Economides PA, Horton ES, Schwartz J, O'Neill, M S, Veves, A, Sarnat, J A, Zanobetti, A, Gold, D R, Economides, P A, Horton, E S, and Schwartz, J
- Abstract
Background: Particulate air pollution has been associated with several adverse cardiovascular health outcomes, and people with diabetes may be especially vulnerable. One potential pathway is inflammation and endothelial dysfunction-processes in which cell adhesion molecules and inflammatory markers play important roles.Aim: To examine whether plasma levels of soluble intercellular adhesion molecule 1 (ICAM-1), vascular cell adhesion molecule 1 (VCAM-1) and von Willebrand factor (vWF) were associated with particle exposure in 92 Boston area residents with type 2 diabetes.Methods: Daily average ambient levels of air pollution (fine particles (PM2.5), black carbon (BC) and sulphates) were measured approximately 500 m from the patient examination site and evaluated for associations with ICAM-1, VCAM-1 and vWF. Linear regressions were fit to plasma levels of ICAM-1, VCAM-1 and vWF, with the particulate pollutant index, apparent temperature, season, age, race, sex, glycosylated haemoglobin, cholesterol, smoking history and body mass index as predictors.Results: Air pollutant exposure measures showed consistently positive point estimates of association with the inflammatory markers. Among participants not taking statins and those with a history of smoking, associations between PM(2.5), BC and VCAM-1 were particularly strong.Conclusions: These results corroborate evidence suggesting that inflammatory mechanisms may explain the increased risk of air pollution-associated cardiovascular events among those with diabetes. [ABSTRACT FROM AUTHOR]- Published
- 2007
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34. Short-term effects of air pollution on heart rate variability in senior adults in Steubenville, Ohio.
- Author
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Luttmann-Gibson H, Suh HH, Coull BA, Dockery DW, Sarnat SE, Schwartz J, Stone PH, and Gold DR
- Published
- 2006
- Full Text
- View/download PDF
35. Home endotoxin exposure and wheeze in infants: correction for bias due to exposure measurement error.
- Author
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Horick N, Weller E, Milton DK, Gold DR, Li R, and Spiegelman D
- Abstract
Exposure to elevated levels of endotoxin in family-room dust was previously observed to be significantly associated with increased wheeze in the first year of life among a cohort of 404 children in the Boston, Massachusetts, metropolitan area. However, it is likely that family-room dust endotoxin was a surrogate for airborne endotoxin exposure. Therefore, a related substudy characterized the relationship between levels of airborne household endotoxin and the level of endotoxin present in house dust, in addition to identifying other significant predictors of airborne endotoxin in the home. We now reexamine the relationship between endotoxin exposure and wheeze under the assumption that the level of airborne endotoxin in the home is the exposure of interest and that the amount of endotoxin in household dust is a surrogate for this exposure. We applied a measurement error correction technique, using all available data to estimate the effect of endotoxin exposure in terms of airborne concentration and accounting for the measurement error induced by using house-dust endotoxin as a surrogate measure in the portion of the data in which airborne endotoxin could not be directly measured. After adjusting for confounding by lower respiratory infection status and race/ethnicity, endotoxin exposure was found to be significantly associated with a nearly 6-fold increase in prevalence of wheeze for a one interquartile range increase in airborne endotoxin (95% confidence interval, 1.2-26) among the 360 children in households with dust endotoxin levels between the 5th and 95th percentiles. [ABSTRACT FROM AUTHOR]
- Published
- 2006
36. Increased risk of paroxysmal atrial fibrillation episodes associated with acute increases in ambient air pollution.
- Author
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Rich DQ, Mittleman MA, Link MS, Schwartz J, Luttmann-Gibson H, Catalano PJ, Speizer FE, Gold DR, and Dockery DW
- Abstract
OBJECTIVES: We reported previously that 24-hr moving average ambient air pollution concentrations were positively associated with ventricular arrhythmias detected by implantable cardioverter defibrillators (ICDs). ICDs also detect paroxysmal atrial fibrillation episodes (PAF) that result in rapid ventricular rates. In this same cohort of ICD patients, we assessed the association between ambient air pollution and episodes of PAF. DESIGN: We performed a case-crossover study. PARTICIPANTS: Patients who lived in the Boston, Massachusetts, metropolitan area and who had ICDs implanted between June 1995 and December 1999 (n=203) were followed until July 2002. EVALUATIONS/MEASUREMENTS: We used conditional logistic regression to explore the association between community air pollution and 91 electrophysiologist-confirmed episodes of PAF among 29 subjects. RESULTS: We found a statistically significant positive association between episodes of PAF and increased ozone concentration (22 ppb) in the hour before the arrhythmia (odds ratio=2.08; 95% confidence interval=1.22, 3.54; p=0.001). The risk estimate for a longer (24-hr) moving average was smaller, thus suggesting an immediate effect. Positive but not statistically significant risks were associated with fine particles, nitrogen dioxide, and black carbon. CONCLUSIONS: Increased ambient O3 pollution was associated with increased risk of episodes of rapid ventricular response due to PAF, thereby suggesting that community air pollution may be a precipitant of these events. [ABSTRACT FROM AUTHOR]
- Published
- 2006
37. Diabetes enhances vulnerability to particulate air pollution-associated impairment in vascular reactivity and endothelial function.
- Author
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O'Neill MS, Veves A, Zanobetti A, Sarnat JA, Gold DR, Economides PA, Horton ES, and Schwartz J
- Published
- 2005
38. HIV-associated cervicodorsal lipodystrophy: etiology and management.
- Author
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Gold DR, Annino DJ Jr., Gold, Daniel R, and Annino, Donald J Jr
- Abstract
Objectives: To familiarize the otolaryngologist with the evaluation and management of cervicodorsal manifestations of lipodystrophy in patients who have been treated with HIV protease inhibitor medications. In addition, to share the benefits obtainable with ultrasonic tumescent liposuction treatment.Study Design: Retrospective chart review of patients presenting to the senior author with symptomatic hypertrophic cervicodorsal fat pad attributable to HIV infection and HIV protease inhibitor use.Results: Eight patients presented for evaluation of hypertrophic cervicodorsal fat pads between January 1, 2002 and December 31, 2004. All patients had been on protease inhibitors in the past and had minimal resolution after discontinuing offending agent. Most common presenting problems include disfigurement, limited range of upper extremity and neck motion, neck and back discomfort, and difficulty with sleep including sleep-study-confirmed obstructive sleep apnea. Five of eight patients underwent ultrasonic tumescent liposuction. Three patients had satisfactory improvement of symptoms after the first surgery, whereas the other two required additional operative sessions. No complications of hematoma, seroma, infection, prolonged pain, or re-accumulation of fat pad were encountered. The primary obstacle in the three nonoperative patients was insurance denial on the basis of deemed lack of established necessity.Conclusions: Cervicodorsal lipodystrophy is a well-recognized outcome of prolonged HIV infection and side effect of certain HIV medications. Patients may present with both esthetic and functional issues related to the excess tissue. Although cessation of associated medications may halt further progression, this alone does resolve the symptoms. Ultrasonic tumescent liposuction is shown in this study to be a well-suited modality for reduction of this fibrous adipose tissue. Multiple sessions may be necessary to achieve satisfactory results because of the tenacity of the tissue. It is important for the otolaryngologist to be familiar with the head and neck issues relevant to this disorder and its treatment. [ABSTRACT FROM AUTHOR]- Published
- 2005
39. Ambient pollution and blood pressure in cardiac rehabilitation patients.
- Author
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Zanobetti A, Canner MJ, Stone PH, Schwartz J, Sher D, Eagan-Bengston E, Gates KA, Hartley LH, Suh H, Gold DR, Zanobetti, Antonella, Canner, Marina Jacobson, Stone, Peter H, Schwartz, Joel, Sher, David, Eagan-Bengston, Elizabeth, Gates, Karen A, Hartley, L Howard, Suh, Helen, and Gold, Diane R
- Published
- 2004
- Full Text
- View/download PDF
40. Ambient air pollution and oxygen saturation.
- Author
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DeMeo DL, Zanobetti A, Litonjua AA, Coull BA, Schwartz J, and Gold DR
- Abstract
We investigated the association between fine particulate air pollution and oxygen saturation as measured with a peripheral oxygen saturation monitor during a 12-week repeated-measures study of 28 older Boston residents. Oxygen saturation and air pollution particulates with a mean diameter less than or equal to 2.5 microm were measured continuously during a protocol of rest, standing, exercise, postexercise rest, and 20 cycles of slow, paced breathing. In fixed-effect models, mean pollution concentration was associated with reduced oxygen saturation during the baseline rest period (6 hours: mean, -0.173%; 95% confidence interval [CI], -0.345 to -0.001), postexercise (6 hours: mean, -0.173%; 95% CI, -0.332 to -0.014), with a trend toward decrease during postexercise paced breathing (6 hours: mean, -0.142%; 95% CI, -0.292 to 0.007) but not during exercise. Participants taking beta-blockers had a greater pollution-related decrease in oxygen saturation at rest (6 hours: mean, -0.769%; 95% CI, -1.210 to -0.327) (interaction for particulates with a mean diameter less than or equal to 2.5 microm by beta-blocker, p < 0.0005) than did those not taking beta-blockers (p > 0.25). The reduction in oxygen saturation associated with air pollution may result from subtle particulate-related pulmonary vascular and/or inflammatory changes. Further investigation may contribute to our understanding of the mechanisms through which particulates may increase respiratory and cardiac morbidity among vulnerable populations. [ABSTRACT FROM AUTHOR]
- Published
- 2004
- Full Text
- View/download PDF
41. Fungal levels in the home and lower respiratory tract illnesses in the first year of life.
- Author
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Stark PC, Burge HA, Ryan LM, Milton DK, and Gold DR
- Abstract
The association between home dampness and lower respiratory symptoms in children has been well documented. Whether fungal exposures contribute to this association is uncertain. In a prospective birth cohort of 499 children of parents with asthma/allergies, we examined in-home fungal concentrations as predictors of lower respiratory illnesses (LRI) (croup, pneumonia, bronchitis, and bronchiolitis) in the first year. In multivariate analyses, we found a significant increased relative risk (RR) between LRI and high levels (more than the 90th percentile) of airborne Penicillium (RR = 1.73, 95% confidence interval [CI], 1.23, 2.43), dust-borne Cladosporium (RR = 1.52; CI, 1.02, 2.25), Zygomycetes (RR = 1.96; CI, 1.35, 2.83), and Alternaria (RR = 1.51; CI, 1.00, 2.28), after controlling for sex, presence of water damage or visible mold/mildew, born in winter, breastfeeding, and being exposed to other children through siblings. In a multivariate analysis, the RR of LRI was elevated in households with any fungal level at more than the 90th percentile (RR = 1.86; CI, 1.21, 2.88). Exposure to high fungal levels increased the risk of LRI in infancy, even for infants with nonwheezing LRI. Actual mechanisms remain unknown, but fungi and their components (glucans, mycotoxins, and proteins) may increase the risk of LRI by acting as irritants or through increasing susceptibility to infection. [ABSTRACT FROM AUTHOR]
- Published
- 2003
- Full Text
- View/download PDF
42. Day care attendance in early life, maternal history of asthma, and asthma at the age of 6 years.
- Author
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Celedón JC, Wright RJ, Litonjua AA, Sredl D, Ryan L, Weiss ST, and Gold DR
- Abstract
Among children not selected on the basis of a parental history of atopy, day care attendance in early life is inversely associated with asthma at school age. We examined the relation between day care in the first year of life and asthma, recurrent wheezing, and eczema at the age of 6 years and wheezing in the first 6 years of life among 453 children with parental history of atopy followed from birth. Among all study participants, day care in the first year of life was inversely associated with eczema (odds ratio [OR] = 0.3, 95% confidence interval [CI] = 0.1-0.8). Day care attendance in early life was associated with a decreased risk of asthma (OR = 0.3, 95% CI = 0.1-0.7) and recurrent wheezing (OR = 0.3, 95% CI = 0.1-0.9) at the age of 6 years and with a decreased risk of any wheezing after the age of 4 years only among children without maternal history of asthma. Among children with maternal history of asthma, day care in early life had no protective effect on asthma or recurrent wheezing at the age of 6 years but was instead associated with an increased risk of wheezing in the first 6 years of life. Our findings suggest that maternal history of asthma influences the relation between day care-related exposures and childhood asthma. [ABSTRACT FROM AUTHOR]
- Published
- 2003
- Full Text
- View/download PDF
43. Effects of cigarette smoking on lung function in adolescent boys and girls.
- Author
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Gold DR, Wang X, Wypij D, Speizer FE, Ware JH, and Dockery DW
- Published
- 1996
44. Driving without brakes.
- Author
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Gold, Dr. Mark and Simon, Hiam
- Subjects
MAJORITIES ,BRAKE systems ,JUDICIAL reform ,JUSTICE administration ,JUDGES - Abstract
Israel's first Knesset, Israel's parliament, sitting in 1950, was faced with a bloc of legislators who felt there was no need for a Jewish state to have a secular constitution. While Israel generated a marvelous document, the Declaration of Establishment, in which it proclaimed the State of Israel's existence and provided a vision to guide its governance, it failed to create a constitution. The streets were filled with Israelis protesting the proposed judicial reforms that would eviscerate Israel's Supreme Court, politicize court appointments, and hobble the rights of Israeli citizens. [Extracted from the article]
- Published
- 2023
45. Agreement between parent and student responses to an asthma and allergy questionnaire in a diverse, inner-city elementary school population.
- Author
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Baxi SN, Sheehan WJ, Gaffin JM, Yodying J, Panupattanapong S, Lane JP, Fu C, Hoffman EB, Gold DR, Phipatanakul W, Baxi, Sachin N, Sheehan, William J, Gaffin, Jonathan M, Yodying, Jirawadee, Panupattanapong, Sirada, Lane, Jeffrey P, Fu, Chunxia, Hoffman, Elaine B, Gold, Diane R, and Phipatanakul, Wanda
- Published
- 2011
- Full Text
- View/download PDF
46. Inhaled corticosteroids for young children with wheezing.
- Author
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Gold DR and Fuhlbrigge AL
- Published
- 2006
47. IT'S NOT ABOUT LINKING GUN VIOLENCE AND MENTAL ILLNESS.
- Author
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Gold, Dr. Jessica and Ranney, Dr. Megan
- Subjects
SHOOTINGS (Crime) ,MENTAL illness ,MASS shootings ,VIOLENT crimes ,PEOPLE with mental illness ,CRIME victims - Abstract
The article analyzes the association between gun violence and mental illness in the U.S. Political leaders such as President Donald Trump and Senator Bernie Sanders blamed mental illness for the two mass shootings in El Paso, Texas, and Dayton, Ohio. But there is no factual relationship between violence and mental illness. It is noted that people with mental illness are more likely to be victims of crimes than perpetrators.
- Published
- 2019
48. Severe Vitamin D Deficiency: A Prerequisite for COPD Responsiveness to Vitamin D Supplementation?
- Author
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Gold DR and Manson JE
- Published
- 2012
49. Pearls and Oy-sters: Central fourth nerve palsies.
- Author
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Gold DR, Shin RK, and Galetta S
- Published
- 2012
- Full Text
- View/download PDF
50. Clinical Reasoning: A 55-year-old woman with vertigo: A dizzying conundrum.
- Author
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Gold DR and Reich SG
- Published
- 2012
- Full Text
- View/download PDF
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