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14. Early neonatal outcomes of very-low-birth-weight infants in Turkey: A prospective multicenter study of the Turkish Neonatal Society

Author

Koc, Esin, primary, Demirel, Nihal, additional, Bas, Ahmet Yagmur, additional, Ulubas Isik, Dilek, additional, Hirfanoglu, Ibrahim Murat, additional, Tunc, Turan, additional, Sari, Fatma Nur, additional, Karatekin, Guner, additional, Ozdemir, Ramazan, additional, Altunhan, Huseyin, additional, Cetinkaya, Merih, additional, Ozcan, Beyza, additional, Ozkiraz, Servet, additional, Calkavur, Sebnem, additional, Tekgunduz, Kadir Serafettin, additional, Tastekin, Ayhan, additional, Ozlu, Ferda, additional, Mutlu Ozyurt, Banu, additional, Ozdemir, Ahmet, additional, Cetinkaya, Bilin, additional, Demirelli, Yasar, additional, Koklu, Esad, additional, Celik, Ulker, additional, Tarakci, Nuriye, additional, Armangil, Didem, additional, Okulu, Emel, additional, Narter, Fatma, additional, Mutlu, Birgul, additional, Mert, Mustafa Kurthan, additional, Bulbul, Ali, additional, Asker, Huseyin Selim, additional, Uygur, Ozgun, additional, Uslu, Ilker Sait, additional, Ertugrul, Sabahattin, additional, Aydemir, Cumhur, additional, Celik, Hasan Tolga, additional, Kucuktasci, Kazim, additional, Arslan, Selda, additional, Ergin, Hacer, additional, Zenciroglu, Aysegul, additional, Yurttutan, Sadik, additional, Orman, Aysen, additional, Tuncer, Oguz, additional, Yasa, Beril, additional, Acunas, Betul, additional, Takci, Sahin, additional, Gokmen, Zeynel, additional, Ozkan, Hilal, additional, Comert, Serdar, additional, Ustun, Nuran, additional, Mutlu, Mehmet, additional, Bayraktar, Bilge Tanyeri, additional, Bilgin, Leyla, additional, Tuzun, Funda, additional, Aydemir, Ozge, additional, Gursoy, Tugba, additional, Akdag, Arzu, additional, Memisoglu, Asli, additional, Can, Emrah, additional, Terek, Demet, additional, Beken, Serdar, additional, Turan, Ozden, additional, Guzoglu, Nilufer, additional, Ors, Rahmi, additional, Kale, Yusuf, additional, Hekimoglu, Berna, additional, Aylanc, Hakan, additional, Eroglu, Funda, additional, Sahin, Suzan, additional, Konak, Murat, additional, Sarici, Dilek, additional, Kilic, Ilknur, additional, and Hakan, Nilay, additional

Published
2019
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15. Incidence, risk factors and severity of retinopathy of prematurity in Turkey (TR-ROP study): a prospective, multicentre study in 69 neonatal intensive care units

Author

Bas, Ahmet Yagmur, Demirel, Nihal, Koc, Esin, Isik, Dilek Ulubas, Hirfanoglu, Ibrahim Murat, Tunc, Turan, Sari, Fatma Nur, Karatekin, Guner, Koklu, Esad, Altunhan, Huseyin, Turgut, Hatice, Narter, Fatma, Tarakci, Nuriye, Tekgunduz, Kadir Serafettin, Ozkiraz, Servet, Aydemir, Cumhur, Ozdemir, Ahmet, Cetinkaya, Bilin, Kazanci, Ebru, Tastekin, Ayhan, Calkavur, Sebnem, Ozyurt, Banu Mutlu, Demirelli, Yasar, Asker, Huseyin Selim, Mutlu, Birgul, Uygur, Ozgun, Ozkan, Hilal, Armangil, Didem, Ozlu, Ferda, Mert, Mustafa Kurthan, Ergin, Hacer, Ozcan, Beyza, Bas, Evrim Kiray, Okulu, Emel, Acunas, Betul, Celik, Ulker, Uslu, Sait Ilker, Mutlu, Mehmet, Demir, Nihat, Eroglu, Funda, Gokmen, Zeynel, Beken, Serdar, Bayraktar, Bilge Tanyeri, Hakan, Nilay, Kucuktasci, Kazim, Orman, Aysen, Comert, Serdar, Ertugrul, Sabahattin, Ustun, Nuran, Sahin, Ozlem, Terek, Demet, Kale, Yusuf, Konak, Murat, Yurttutan, Sadik, Aydemir, Ozge, Zenciroglu, Aysegul, Sarici, Dilek, Guzoglu, Nilufer, Hamilcikan, Sahin, Gursoy, Tugba, Tuzun, Funda, Ors, Rahmi, Arslan, Selda, Akdag, Arzu, Memisoglu, Asli, Yasa, Beril, Hekimoglu, Berna, Turan, Ozden, Aylanc, Hakan, Takci, Sahin, Celik, Tolga, Sahin, Suzan, Kilic, Ilknur, Kara, Caner, Tunay, Zuhal Ozen, Celik, Gokhan, Gozen, Ibrahim, Satirtav, Gunhal, Polat, Nihat, Oral, Ayse Yesim, Tokgoz, Mine, Keles, Sadullah, Bilgin, Burak, Ugurbas, Silay Canturk, Karaca, Cagatay, Keskek, Nedime Sahinoglu, Ekinci, Dilbade Yildiz, Balci, Ozlem, Altan, Emir Volkan, Bakbak, Sevda, Ceylan, Nihan Aksu, Kimyon, Sabit, Alyamac, Gunay, Ture, Gamze, Yildiz, Meral, Calis, Feyza, Sizmaz, Selcuk, Sukgen, Emine, Cetin, Ebru Nevin, Ozcimen, Muammer, Demir, Semra Tiryaki, Atila, Huban, Ozal, Altan, Tufaner, Gokhan, Yucel, Ozlem Eski, Kola, Mehmet, Seven, Erbil, Ozdek, Sengul, Durukan, Ali Hakan, Kal, Ali, Celebi, Ali Riza Cenk, Koytak, Ibrahim Arif, Alacamli, Goksu, Esme, Arif, Catak, Onur, Perente, Irfan, Sahin, Alparslan, Akcakaya, Aylin Ardagil, Kiray, Gulunay, Nalcaci, Serhat, Aksoy, Umit, Bakbak, Berker, Comez, Aysegul, Gursoy, Huseyin, Kabatas, Emrah Utku, Petricli, Ikbal Seza, Yumusak, Mehmet Erhan, Kirgiz, Ahmet, Uludag, Gunay, Yaman, Aylin, Dadaci, Zeynep, Karatas, Ali, Celiker, Hande, Cebeci, Zafer, Esenulku, Mahmut Cenap, Akkoyun, Imren, Ersan, Ismail, Demir, Selim, Kadayifcilar, Sibel, Unsal, Ayse Ipek Akyuz, Hocaoglu, Mumin, Grp, T. R.-R.O.P. Study, Ege Üniversitesi, Zonguldak Bülent Ecevit Üniversitesi, Çukurova Üniversitesi, Çocuk Sağlığı ve Hastalıkları, KOYTAK, İBRAHİM ARİF, Uludağ, Günay (ORCID & YÖK ID 175586), Gürsoy, Tuğba (ORCID 0000-0002-6084-4067 & YÖK ID 214691), Baş, Ahmet Yağmur, Demirel, Nihal, Koç, Esin, Işık, Dilek Ulubaş, Hirfanoğlu, İbrahim Murat, Tunç, Turan, Sarı, Fatma Nur, Karatekin, Güner, Köklü, Esad, Altunhan, Hüseyin, Turgut, Hatice, Narter, Fatma, Tarakçı, Nuriye, Tekgündüz, Kadir Şerafettin, Özkiraz, Servet, Aydemir, Cumhur, Özdemir, Ahmet, Çetinkaya, Bilin, Kazancı, Ebru, Taştekin, Ayhan, Calkavur, Şebnem, Özyurt, Banu Mutlu, Demirelli, Yaşar, Asker, Hüseyin Selim, Mutlu, Birgul, Uygur, Özgün, Özkan, Hilal, Armangil, Didem, Özlü, Ferda, Mert, Mustafa Kurthan, Ergin, Hacer, Özcan, Beyza, Baş, Evrim Kıray, Okulu, Emel, Acunas, Betül, Çelik, Ülker, Uslu, Sait İlker, Mutlu, Mehmet, Demir, Nihat, Eroğlu, Funda, Gökmen, Zeynel, Beken, Serdar, Bayraktar, Bilge Tanyeri, Hakan, Nilay, Küçüktaşçı, Kazım, Orman, Ayşen, Cömert, Serdar, Ertuğrul, Sabahattin, Üstün, Nuran, Şahin, Özlem, Terek, Demet, Kale, Yusuf, Konak, Murat, Yurttutan, Sadık, Aydemir, Özge, Zenciroğlu, Aysegül, Sarıcı, Dilek, Güzoğlu, Nilüfer, Hamilçıkan, Şahin, Tüzün, Funda, Örs, Rahmi, Arslan, Selda, Akdağ, Arzu, Memişoğlu, Aslı, Yasa, Beril, Hekimoğlu, Berna, Turan, Özden, Aylanc, Hakan, Takçı, Şahin, Çelik, Tolga, Şahin, Suzan, Kılıç, İlknur, Kara, Caner, Tunay, Zuhal Özen, Çelik, Gökhan, Gözen, İbrahim, Satırtav, Günhal, Polat, Nihat, Oral, Ayşe Yeşim, Tokgöz, Mine, Keleş, Sadullah, Bilgin, Burak, Uğurbaş, Silay Cantürk, Karaca, Çağatay, Keşkek, Nedime Şahinoğlu, Ekinci, Dilbade Yıldız, Balcı, Özlem, Altan, Emir Volkan, Bakbak, Sevda, Ceylan, Nihan Aksu, Kimyon, Sabit, Alyamaç, Günay, Türe, Gamze, Yıldız, Meral, Çalış, Feyza, Sızmaz, Selçuk, Sukgen, Emine, Çetin, Ebru Nevin, Özçimen, Muammer, Demir, Semra Tiryaki, Atila, Huban, Özal, Altan, Tufaner, Gökhan, Yücel, Özlem Eski, Kola, Mehmet, Seven, Erbil, Özdek, Şengül, Durukan, Ali Hakan, Kal, Ali, Çelebi, Ali Riza Cenk, Koytak, İbrahim Arif, Alaçamlı, Göksu, Esme, Arif, Çatak, Onur, Perente, İrfan, Şahin, Alparslan, Akçakaya, Aylin Ardagil, Kıray, Gülünay, Nalçacı, Serhat, Aksoy, Ümit, Bakbak, Berker, Çömez, Ayşegül, Gürsoy, Hüseyin, Kabataş, Emrah Utku, Petricli, İkbal Seza, Yumuşak, Mehmet Erhan, Kırgız, Ahmet, Yaman, Aylin, Dadacı, Zeynep, Karataş, Ali, Çeliker, Hande, Cebeci, Zafer, Esenülkü, Mahmut Cenap, Akkoyun, İmren, Ersan, İsmail, Demir, Selim, Kadayıfçılar, Sibel, Ünsal, Ayşe İpek Akyüz, Hocaoğlu, Mümin, School of Medicine, Department of Internal Medicine, MÜ, Kırıkkale Üniversitesi, Selçuk Üniversitesi, Bas, Ahmet Yagmur, Koc, Esin, Isik, Dilek Ulubas, Hirfanoglu, Ibrahim Murat, Tunc, Turan, Sari, Fatma Nur, Karatekin, Guner, Koklu, Esad, Altunhan, Huseyin, Tarakci, Nuriye, Tekgunduz, Kadir Serafettin, Ozkiraz, Servet, Ozdemir, Ahmet, Cetinkaya, Bilin, Kazanci, Ebru, Tastekin, Ayhan, Calkavur, Sebnem, Ozyurt, Banu Mutlu, Demirelli, Yasar, Asker, Huseyin Selim, Uygur, Ozgun, Ozkan, Hilal, Ozlu, Ferda, Ozcan, Beyza, Bas, Evrim Kiray, Acunas, Betul, Celik, Ulker, Uslu, Sait Ilker, Eroglu, Funda, Gokmen, Zeynel, Kucuktasci, Kazim, Orman, Aysen, Comert, Serdar, Ertugrul, Sabahattin, Ustun, Nuran, Sahin, Ozlem, Yurttutan, Sadik, Aydemir, Ozge, Zenciroglu, Aysegul, Sarici, Dilek, Guzoglu, Nilufer, Hamilcikan, Sahin, Gursoy, Tugba, Tuzun, Funda, Ors, Rahmi, Akdag, Arzu, Memisoglu, Asli, Hekimoglu, Berna, Turan, Ozden, Takci, Sahin, Celik, Tolga, Sahin, Suzan, Kilic, Ilknur, Tunay, Zuhal Ozen, Celik, Gokhan, Gozen, Ibrahim, Satirtav, Gunhal, Oral, Ayse Yesim, Tokgoz, Mine, Keles, Sadullah, Ugurbas, Silay Canturk, Karaca, Cagatay, Keskek, Nedime Sahinoglu, Ekinci, Dilbade Yildiz, Balci, Ozlem, Alyamac, Gunay, Ture, Gamze, Yildiz, Meral, Calis, Feyza, Sizmaz, Selcuk, Cetin, Ebru Nevin, Ozcimen, Muammer, Ozal, Altan, Tufaner, Gokhan, Yucel, Ozlem Eski, Ozdek, Sengul, Celebi, Ali Riza Cenk, Koytak, Ibrahim Arif, Alacamli, Goksu, Catak, Onur, Perente, Irfan, Sahin, Alparslan, Akcakaya, Aylin Ardagil, Kiray, Gulunay, Nalcaci, Serhat, Aksoy, Umit, Comez, Aysegul, Gursoy, Huseyin, Kabatas, Emrah Utku, Petricli, Ikbal Seza, Yumusak, Mehmet Erhan, Kirgiz, Ahmet, Uludag, Gunay, Dadaci, Zeynep, Karatas, Ali, Celiker, Hande, Esenulku, Mahmut Cenap, Akkoyun, Imren, Ersan, Ismail, Kadayifcilar, Sibel, Unsal, Ayse Ipek Akyuz, Hocaoglu, Mumin, OMÜ, Tıp Fakültesi, and Acibadem University Dspace

Subjects
Male, BLOOD-TRANSFUSION, Pediatrics, Turkey, INFANTS, Logistic regression, 0302 clinical medicine, Risk Factors, FOR-GESTATIONAL-AGE, Prevalence, Birth Weight, Infant, Very Low Birth Weight, Prospective Studies, Prospective cohort study, [Anahtar Kelime Yok], Neovascularisation, Incidence, Incidence (epidemiology), Gestational age, Retinopathy of prematurity, Clinical Science, Sensory Systems, Female, Infant, Premature, Child health (paediatrics), Retina, Treatment medical, congenital, hereditary, and neonatal diseases and abnormalities, medicine.medical_specialty, Birth weight, Gestational Age, Sepsis, 03 medical and health sciences, Cellular and Molecular Neuroscience, Neonatal Screening, Intensive Care Units, Neonatal, 030225 pediatrics, Intensive care, medicine, Humans, Retinopathy of Prematurity, business.industry, Child Health (paediatrics), Infant, Newborn, [No Keywords], Infant, medicine.disease, eye diseases, Ophthalmology, For-Gestational-Age, TR-ROP Study, 030221 ophthalmology & optometry, Treatment Medical, Blood-Transfusion, WEIGHT, Weight, Infants, Severity of Retinopathy, business, Medicine
Abstract

Background To evaluate the prevalence, risk factors and treatment of retinopathy of prematurity (ROP) in Turkey and to establish screening criteria for this condition., Methods A prospective cohort study (TR-ROP) was performed between 1 April 2016 and 30 April 2017 in 69 neonatal intensive care units (NICUs). Infants with a birth weight (BW)=1500 g or gestational age (GA) 1500 g or GA> 32 weeks with an unstable clinical course were included in the study. Predictors for the development of ROP were determined by logistic regression analyses., Results The TR-ROP study included 6115 infants: 4964 (81%) with a GA 32 weeks. Overall, 27% had any stage of ROP and 6.7% had severe ROP. A lower BW, smaller GA, total days on oxygen, late-onset sepsis, frequency of red blood cell transfusions and relative weight gain were identified as independent risk factors for severe ROP in infants with a BW=1500 g. Of all infants, 414 needed treatment and 395 (95.4%) of the treated infants had a BW, Conclusions Screening of infants with a GA

Published
2018

17. Prophylactic intravenous paracetamol use in extremely premature infants for patent ductus arteriosus.

Author

Silahli, Musa, Gokmen, Zeynel, and Tekin, Mehmet

Subjects
PATENT ductus arteriosus, INTRAVENOUS therapy, ACQUISITION of data methodology, CLINICAL trials, CEREBRAL hemorrhage, ACETAMINOPHEN, GESTATIONAL age, RETROSPECTIVE studies, TREATMENT duration, VERY low birth weight, TREATMENT effectiveness, COMPARATIVE studies, SEX distribution, MEDICAL records, HEMODYNAMICS, COMORBIDITY, EVALUATION
Abstract

Patency of ductus arteriosus (PDA) is a very common problem among extremely low birth weight infants (ELBW). Hemodynamic instability caused by PDA is associated with important morbidities. This study aims to evaluate the effects of prophylactic intravenous paracetamol on the hemodynamically significant patent ductus arteriosus (hsPDA). A total of 75 infants of <28 week-gestational age were enrolled into the study which was retrospective. Prophylactic paracetamol as the experimental group and none-prophylaxis group as the control group were compared in the study. There were 35 subjects in the prophylactic paracetamol group (PPG), and 40 in the control group. Primary outcome measures were ductal closure, ductal diameter, grade 3–4 IVH, and repeated ibuprofen need for the treatment of hsPDA. At the time of the evaluation by echo, hsPDA, and the diameter of the ductus higher than 1 mm were found significantly lower in the PPG (p=0.004 and p=0.013). Additionally, the repeated course of ibuprofen was significantly lower in the PPG (p=0.025). Secondary outcomes were the other perinatal morbidities. According to the results of the study, the male gender is 6.6, and the paracetamol use is 5.5 times more likely to suffer from ROP. The results of the study indicated that prophylactic paracetamol use in ELBW infants decreases the likelihood of hsPDA. The repeated course of ibuprofen for the treatment of hsPDA can be reduced. Furthermore, it can be understood that while prophylactic use of paracetamol is preventive for intraventricular hemorrhage, it does not function in the same way for retinopathy of prematurity or bronchopulmonary dysplasia. It might even worse the retinopathy of prematurity. Further prospective randomized controlled and larger sample-sized studies are needed. [ABSTRACT FROM AUTHOR]

Published
2021
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19. Effect of Maternal Depression on Brain-derived Neurotrophic Factor Levels in Fetal Cord Blood

Author

Sonmez, Erdem Onder, primary, Uguz, Faruk, additional, Sahingoz, Mine, additional, Sonmez, Gulsum, additional, Kaya, Nazmiye, additional, Camkurt, Mehmet Akif, additional, Gokmen, Zeynel, additional, Basaran, Mustafa, additional, Gezginc, Kazim, additional, Erdem, Sami Sait, additional, Dulger, Hasan Haluk, additional, and Tasyurek, Erkan, additional

Published
2019
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21. International Nosocomial Infection Control Consortium (INICC) national report on device-associated infection rates in 19 cities of Turkey, data summary for 2003-2012

Author

Leblebicioglu, Hakan, Erben, Nurettin, Rosenthal, Victor Daniel, Atasay, Begum, Erbay, Ayse, Unal, Serhat, Senol, Gunes, Willke, Ayse, Ozgultekin, Asu, Altin, Nilgun, Bakir, Mehmet, Oncul, Oral, Ersoz, Gulden, Ozdemir, Davut, Yalcin, Ata Nevzat, Ozdemir, Halil, Yildizdas, Dincer, Koksal, Iftihar, Aygun, Canan, Sirmatel, Fatma, Sener, Alper, Tuna, Nazan, Akan, OTzay Arikan, Turgut, Huseyin, Demiroz, A. Pekcan, Kendirli, Tanil, Alp, Emine, Uzun, Cengiz, Ulusoy, Sercan, Arman, Dilek, Ozgunes, Ilhan, Usluer, Gaye, Kilic, Atila, Arsan, Saadet, Cabadak, Hatice, Sen, Suha, Gelebek, Yasemin, Zengin, Humeyra, Topeli, Arzu, Alper, Yusuf, Meric, Meliha, Azak, Emel, Inan, Asuman, Turan, Guldem, Haznedaroglu, Tuncer, Gorenek, Levent, Acar, Ali, Cesur, Salih, Engin, Aynur, Kaya, Ali, Kuyucu, Necdet, Geyik, Mehmet Faruk, Aydin, Ozlem Cetinkaya, Erdogan, Nurse Selvi, Turhan, Ozge, Gunay, Nurgul, Gumus, Eylul, Dursun, Oguz, Esen, Saban, Ulger, Fatma, Dilek, Ahmet, Yilmaz, Hava, Sunbul, Mustafa, Gokmen, Zeynel, Ozdemir, Sonay Incesoy, Horoz, Ozden Ozgur, Yylmaz, Gurdal, Kaya, Selcuk, Ulusoy, Hulya, Kucukoduk, Sukru, Ustun, Cemal, Baysal, Abant Izzet, Otkun, Metin, Tulunay, Melek, Oral, Mehmet, Unal, Necmettin, Cengiz, Mustafa, Yilmaz, Leyla, Sacar, Suzan, Sungurtekin, Hulya, Ugurcan, Dogac, Yetkin, M. Arzu, Bulut, Cemal, Erdinc, F. Sebnem, Hatipoglu, Cigdem Ataman, Ince, Erdal, Ciftci, Ergin, Odek, Caglar, Yaman, Ayhan, Karbuz, Adem, Aldemir, Bilge, Kilic, Aysegul Ulu, Arda, Bilgin, Bacakoglu, Feza, Hizel, Kenan, [Leblebicioglu, Hakan -- Esen, Saban -- Ulger, Fatma -- Dilek, Ahmet -- Yilmaz, Hava -- Sunbul, Mustafa] Ondokuz Mayis Univ, Sch Med, Samsun, Turkey -- [Erben, Nurettin -- Ozgunes, Ilhan -- Usluer, Gaye] Eskisehir Osmangazi Univ, Eskisehir, Turkey -- [Rosenthal, Victor Daniel] Int Nosocomial Infect Control Consortium, Ave 4580,Floor 12,Apt D, RA-1195 Buenos Aires, DF, Argentina -- [Atasay, Begum -- Kilic, Atila -- Arsan, Saadet] Ankara Univ, Sch Med, Fac Paediat, Dept Newborn Med, TR-06100 Ankara, Turkey -- [Erbay, Ayse -- Cabadak, Hatice -- Sen, Suha] Turkiye Yuksek Ihtisas Educ & Res Hosp, Ankara, Turkey -- [Unal, Serhat -- Gelebek, Yasemin -- Zengin, Humeyra -- Topeli, Arzu -- Alper, Yusuf] Hacettepe Univ, Sch Med, Ankara, Turkey -- [Senol, Gunes] Suat Seren Chest Dis & Chest Surg Training Hosp, Izmir, Turkey -- [Willke, Ayse -- Meric, Meliha -- Azak, Emel] Kocaeli Univ, Fac Med, Kocaeli, Turkey -- [Ozgultekin, Asu -- Inan, Asuman -- Turan, Guldem] Haydarpasa Numune Training & Res Hosp, Istanbul, Turkey -- [Altin, Nilgun -- Cesur, Salih] Etlik Ihtisas Training & Educ Hosp, Ankara, Turkey -- [Bakir, Mehmet -- Engin, Aynur] Cumhuriyet Univ, Sch Med, Sivas, Turkey -- [Oncul, Oral -- Haznedaroglu, Tuncer -- Gorenek, Levent -- Acar, Ali] Gulhane Mil Med Acad, Haydarpasa Training Hosp, Istanbul, Turkey -- [Ersoz, Gulden -- Kaya, Ali -- Kuyucu, Necdet] Mersin Univ, Fac Med, Mersin, Turkey -- [Ozdemir, Davut -- Geyik, Mehmet Faruk -- Aydin, Ozlem Cetinkaya -- Erdogan, Nurse Selvi] Duzce Univ, Med Sch Infect Dis & Clin Microbiol, Duzce, Turkey -- [Yalcin, Ata Nevzat -- Turhan, Ozge -- Gunay, Nurgul -- Gumus, Eylul -- Dursun, Oguz] Akdeniz Univ, TR-07058 Antalya, Turkey -- [Ozdemir, Halil -- Gokmen, Zeynel -- Ozdemir, Sonay Incesoy] Konya Training & Res Hosp, Konya, Turkey -- [Yildizdas, Dincer -- Horoz, Ozden Ozgur] Cukurova Univ, Balcali Hosp, Adana, Turkey -- [Koksal, Iftihar -- Yylmaz, Gurdal -- Kaya, Selcuk -- Ulusoy, Hulya] Karadeniz Tech Univ, Sch Med, Trabzon, Turkey -- [Aygun, Canan -- Kucukoduk, Sukru] Ondokuz Mayis Univ, Sch Med, Neonatal Unit, Samsun, Turkey -- [Sirmatel, Fatma -- Ustun, Cemal -- Baysal, Abant Izzet] Univ Hosp, Infect Dis & Clin Microbiol, Bolu, Turkey -- [Sener, Alper -- Otkun, Metin] Onsekiz Mart Univ Canakkale, Canakkale, Turkey -- [Tuna, Nazan] Sakarya Univ, Fac Med, Sakarya, Turkey -- [Akan, OTzay Arikan -- Tulunay, Melek -- Oral, Mehmet -- Unal, Necmettin] Ankara Univ, Ibni Sina Hosp, Sch Med, TR-06100 Ankara, Turkey -- [Turgut, Huseyin -- Sacar, Suzan -- Sungurtekin, Hulya -- Ugurcan, Dogac] Pamukkale Univ, Denizli, Turkey -- [Demiroz, A. Pekcan -- Yetkin, M. Arzu -- Bulut, Cemal -- Erdinc, F. Sebnem -- Hatipoglu, Cigdem Ataman] Ankara Numune Training & Res Hosp, Ankara, Turkey -- [Kendirli, Tanil -- Ince, Erdal -- Ciftci, Ergin -- Odek, Caglar -- Yaman, Ayhan -- Karbuz, Adem -- Aldemir, Bilge] Ankara Univ, Sch Med, Dept Paediat Crit Care Med, TR-06100 Ankara, Turkey -- [Alp, Emine -- Kilic, Aysegul Ulu] Erciyes Univ, Fac Med, Kayseri, Turkey -- [Uzun, Cengiz] German Hosp, Istanbul, Turkey -- [Ulusoy, Sercan -- Arda, Bilgin -- Bacakoglu, Feza] Ege Univ, Fac Med, Izmir, Turkey -- [Arman, Dilek -- Hizel, Kenan] Gazi Univ, Sch Med, Ankara, Turkey -- [Cengiz, Mustafa -- Yilmaz, Leyla] Harran Univ, Fac Med, Sanliurfa, Turkey, Ciftci, Ergin -- 0000-0002-4955-160X, Leblebicioglu, Hakan -- 0000-0002-6033-8543, Horoz, Ozden Ozgur -- 0000-0001-7590-650X, Erben, Nurettin -- 0000-0003-0373-0132, Yalcin, Ata Nevzat -- 0000-0002-7243-7354, UNAL, SERHAT -- 0000-0003-1184-4711, MERİÇ KOÇ, MELİHA, Çukurova Üniversitesi, OMÜ, BAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Sırmatel, Fatma, and Ege Üniversitesi

Subjects
Male, Pediatrics, healthcare associated infection, Turkey, Antibiotic resistance, medicine.medical_treatment, health care facilities, manpower, and services, central venous catheter, Network, intensive care unit, preschool child, Turkey (republic), law.invention, Cohort Studies, Nosocomial infection, law, newborn, device infection, Prevalence, Infection control, Prospective Studies, Prospective cohort study, Child, intensive care, catheter infection, Cross Infection, Urinary tract infection, adult, Ventilator-associated pneumonia, Pneumonia, Ventilator-Associated, General Medicine, cohort analysis, INICC, Intensive care unit, infection control, Device-associated infection, Infectious Diseases, female, Equipment and Supplies, Child, Preschool, disease surveillance, Central venous catheter, devices, Cohort study, prospective study, Microbiology (medical), medicine.medical_specialty, Adolescent, Catheter-associated urinary tract infection, infection rate, Bloodstream infection, Article, critically ill patient, length of stay, Intensive care, medicine, Humans, Hospital infection, human, Healthcare-associated infection, urinary catheter, business.industry, Research, Infant, Newborn, Infant, International Nosocomial Infection Consortium, mechanical ventilator, medicine.disease, Nosocomial infection control, major clinical study, mortality, Catheter-Related Infections, Emergency medicine, ventilator associated pneumonia, Central line-associated bloodstream infections, business
Abstract

WOS: 000346433300001, PubMed ID: 25403704, Background: Device-associated healthcare-acquired infections (DA-HAI) pose a threat to patient safety, particularly in the intensive care unit (ICU). We report the results of the International Infection Control Consortium (INICC) study conducted in Turkey from August 2003 through October 2012. Methods: A DA-HAI surveillance study in 63 adult, paediatric ICUs and neonatal ICUs (NICUs) from 29 hospitals, in 19 cities using the methods and definitions of the U.S. NHSN and INICC methods. Results: We collected prospective data from 94,498 ICU patients for 647,316 bed days. Pooled DA-HAI rates for adult and paediatric ICUs were 11.1 central line-associated bloodstream infections (CLABSIs) per 1000 central line (CL)-days, 21.4 ventilator-associated pneumonias (VAPs) per 1000 mechanical ventilator (MV)-days and 7.5 catheter-associated urinary tract infections (CAUTIs) per 1000 urinary catheter-days. Pooled DA-HAI rates for NICUs were 30 CLABSIs per 1000 CL-days, and 15.8 VAPs per 1000 MV-days. Extra length of stay (LOS) in adult and paediatric ICUs was 19.4 for CLABSI, 8.7 for VAP and 10.1 for CAUTI. Extra LOS in NICUs was 13.1 for patients with CLABSI and 16.2 for patients with VAP. Extra crude mortality was 12% for CLABSI, 19.4% for VAP and 10.5% for CAUTI in ICUs, and 15.4% for CLABSI and 10.5% for VAP in NICUs. Pooled device use (DU) ratios for adult and paediatric ICUs were 0.54 for MV, 0.65 for CL and 0.88 for UC, and 0.12 for MV, and 0.09 for CL in NICUs. The CLABSI rate was 8.5 per 1,000 CL days in the Medical Surgical ICUs included in this study, which is higher than the INICC report rate of 4.9, and more than eight times higher than the NHSN rate of 0.9. Similarly, the VAP and CAUTI rates were higher compared with U. S. NHSN (22.3 vs. 1.1 for VAP; 7.9 vs. 1.2 for CAUTI) and with the INICC report (22.3 vs. 16.5 in VAP; 7.9 vs. 5.3 in CAUTI). Conclusions: DA-HAI rates and DU ratios in our ICUs were higher than those reported in the INICC global report and in the US NHSN report., Foundation to Fight against Nosocomial Infections, The funding for the activities carried out at INICC head quarters were provided by the corresponding author, Victor D. Rosenthal, and Foundation to Fight against Nosocomial Infections.

Published
2014

22. Association of Serum Albumin Level and Mortality in Premature Infants

Author

Torer, Birgin, Hanta, Deniz, Yapakci, Ece, Gokmen, Zeynel, Parlakgumus, Ayse, Gulcan, Hande, and Tarcan, Aylin

Subjects
Male, Infant, Newborn, Gestational Age, Infant, Newborn, Diseases, Cohort Studies, Logistic Models, ROC Curve, Predictive Value of Tests, Birth Weight, Humans, Premature Birth, Female, Research Articles, Infant, Premature, Serum Albumin
Abstract

BACKGROUND: Hypoalbuminemia has been proven to be a powerful predictor of mortality in adult patients. However, prognostic value of serum albumin in neonates is not clear. OBJECTIVE: To assess the relationship between serum albumin level within the first day of life and outcome in preterm infants born before 32 weeks of gestation. METHODS: The study was conducted prospectively in Baskent University Hospital between October 2008 and November 2009. Patients were divided by gestational age into two groups as below or of 28 weeks and above 28 weeks. Then serum albumin percentile groups were established within each gestational age group and were defined as 75 percentile groups by combining percentile groups between the two gestational age groups. Three serum albumin percentile groups were compared regarding neonatal outcomes. RESULTS: A total of 199 infants with mean birth weight of 1,272 ± 390 g and mean gestational age of 29.2 ± 2.2 weeks were admitted to the study. The mean serum albumin level was 30.6 ± 4.7 g/l for all patients. The mean serum albumin levels were 25.5 ± 3.8, 30.1 ± 2.7, and 35.3 ± 3.7 g/l for 75 percentile groups, respectively. Prevalence of infants with respiratory distress syndrome and prevalence of infants with sepsis and mortality were significantly higher in

Published
2016

23. Outcome of the Respiratory Syncytial Virus related acute lower respiratory tract infection among hospitalized newborns: a prospective multicenter study

Author

Kiray Bas, E., Koc, E., Hirfanoglu, I.M., Celik, U., Yalaz, M., Ergor, S.N., Duman, N., Iscan, B., Unal, S., Cakir, B., Ertugrul, S., Satar, M., Ozlu, F., Cevit, O., Bolat, F., Bilgili, G., Yigit, Y., Kurt, A., Tekgunduz, K.S., Caner, I., Yildiz, D., Kahvecioglu, D., Oygur, N., Erdogan, Y., Turkmen, M.K., Anik, A., Arsan, Saadet, Atasay, Begum, Ates, Can, Gokmen, Zeynel, Tunc, Turan, Akcakus, Mustafa, Zenciroglu, Aysegul, Akduman, Hasan, Cakir, Ufuk, ERDEVE, ÖMER, Alan, Serdar, Melekoglu, N.A., Celik, I., Korkmaz, A., Ozdemir, R., Karadag, A., Ozer, E., Ilhan, O., Mutlu, M., Aslan, Y., Erener- Ercan, T., Cetinkaya, M., Sahin, O., Akin, M.A., Okumus, N., Demirel, G., Kilic, A., Turkoglu-Unal, E., Bulbul, A., Takci, S., Anuk-Ince, D., Ciftdemir, N.A., Acunas, B., Ozkan, H., Koksal, N., Okulu, E., Demir, N., Tuncer, O., Dizdar, E.A., Oguz, S., Dilmen, U., Bozkaya, D., Sivasli, E., Alan, S., Neonatal Intensive Care Unit, Hitit University Corum Training and Research Hospital, Vedat Dolakay Cad. No: 90A/16 Gaziosmanpasa, Ankara, 06100, Turkey -- Erdeve, O., Division of Neonatology, Department of Pediatrics, Ankara University School of Medicine, Ankara, Turkey -- Cakir, U., Division of Neonatology, Department of Pediatrics, Ankara University School of Medicine, Ankara, Turkey -- Akduman, H., Division of Neonatology, Department of Pediatrics, Ankara University School of Medicine, Ankara, Turkey -- Zenciroglu, A., Neonatal Intensive Care Unit, Dr Sami Ulus Maternity and Children Training and Research Hospital, Ankara, Turkey -- Akcakus, M., Division of Neonatology, Department of Pediatrics, Akdeniz University Medical School, Antalya, Turkey -- Tunc, T., Division of Neonatology, Department of Pediatrics, Gulhane Military School of Medicine, Ankara, Turkey -- Gokmen, Z., Neonatal Intensive Care Unit, Konya Training and Research Hospital, Konya, Turkey -- Ates, C., Department of Biostatistics, Ankara University School of Medicine, Ankara, Turkey -- Atasay, B., Division of Neonatology, Department of Pediatrics, Ankara University School of Medicine, Ankara, Turkey -- Arsan, S., Division of Neonatology, Department of Pediatrics, Ankara University School of Medicine, Ankara, Turkey -- Anik, A., Adnan Menderes University, Faculty of Medicine, Aydin, Turkey -- Turkmen, M.K., Adnan Menderes University, Faculty of Medicine, Aydin, Turkey -- Erdogan, Y., Akdeniz University, Medical School, Antalya, Turkey -- Oygur, N., Akdeniz University, Medical School, Antalya, Turkey -- Kahvecioglu, D., Ankara University, School of Medicine, Ankara, Turkey -- Yildiz, D., Ankara University, School of Medicine, Ankara, Turkey -- Caner, I., Ataturk University, Faculty of Medicine, Erzurum, Turkey -- Tekgunduz, K.S., Ataturk University, Faculty of Medicine, Erzurum, Turkey -- Kurt, A., Balikesir Ataturk Government Hospital, Balikesir, Turkey -- Yigit, Y., Celal Bayar University, Faculty of Medicine, Manisa, Turkey -- Bilgili, G., Celal Bayar University, Faculty of Medicine, Manisa, Turkey -- Bolat, F., Cumhuriyet University, Faculty of Medicine, Sivas, Turkey -- Cevit, O., Cumhuriyet University, Faculty of Medicine, Sivas, Turkey -- Ozlu, F., Cukurova University, Faculty of Medicine, Adana, Turkey -- Satar, M., Cukurova University, Faculty of Medicine, Adana, Turkey -- Ertugrul, S., Dicle University, Faculty of Medicine, Diyarbakir, Turkey -- Cakir, B., Ankara Children's Health Hematology Oncology Research Hospital, Ankara, Turkey -- Unal, S., Ankara Children's Health Hematology Oncology Research Hospital, Ankara, Turkey -- Iscan, B., Dokuz Eylul University, School of Medicine, Izmir, Turkey -- Duman, N., Dokuz Eylul University, School of Medicine, Izmir, Turkey -- Ergor, S.N., Ege University, Faculty of Medicine, Izmir, Turkey -- Yalaz, M., Ege University, Faculty of Medicine, Izmir, Turkey -- Celik, I., Etlik Zübeyde Hanim Women's Health Teaching and Research Hospital, Ankara, Turkey -- Celik, U., Etlik Zübeyde Hanim Women's Health Teaching and Research Hospital, Ankara, Turkey -- Hirfanoglu, I.M., Gazi University, Faculty of Medicine, Ankara, Turkey -- Koc, E., Gazi University, Faculty of Medicine, Ankara, Turkey -- Sivasli, E., Gaziantep University, Faculty of Medicine, Gaziantep, Turkey -- Melekoglu, N.A., Gaziantep University, Faculty of Medicine, Gaziantep, Turkey -- Kiray Bas, E., Gaziantep Children's Hospital, Gaziantep, Turkey -- Bozkaya, D., Hacettepe University, Faculty of Medicine, Ankara, Turkey -- Korkmaz, A., Hacettepe University, Faculty of Medicine, Ankara, Turkey -- Ozdemir, R., Inönü University, Faculty of Medicine, Malatya, Turkey -- Karadag, A., Inönü University, Faculty of Medicine, Malatya, Turkey -- Ozer, E., Tepecik Training and Research Hospital, Izmir, Turkey -- Ilhan, O., Tepecik Training and Research Hospital, Izmir, Turkey -- Mutlu, M., Karadeniz Technical University, Faculty of Medicine, Trabzon, Turkey -- Aslan, Y., Karadeniz Technical University, Faculty of Medicine, Trabzon, Turkey -- Erener- Ercan, T., Kanuni Sultan Suleyman Training and Research Hospital, Istanbul, Turkey -- Cetinkaya, M., Kanuni Sultan Suleyman Training and Research Hospital, Istanbul, Turkey -- Sahin, O., Kayseri Training and Research Hospital, Kayseri, Turkey -- Akin, M.A., Kayseri Training and Research Hospital, Kayseri, Turkey -- Okumus, N., Dr. Sami Ulus Maternity and Children Training and Research Hospital, Ankara, Turkey -- Demirel, G., Samsun Maternal and Child Health Hospital, Samsun, Turkey -- Kilic, A., Samsun Maternal and Child Health Hospital, Samsun, Turkey -- Turkoglu-Unal, E., Sisli Hamidiye Etfal Children Hospital, Istanbul, Turkey -- Bulbul, A., Sisli Hamidiye Etfal Children Hospital, Istanbul, Turkey -- Takci, S., Gaziosmanpasa University, Faculty of Medicine, Tokat, Turkey -- Anuk-Ince, D., Gaziosmanpasa University, Faculty of Medicine, Tokat, Turkey -- Ciftdemir, N.A., Trakya University, School of Medicine, Edirne, Turkey -- Acunas, B., Trakya University, School of Medicine, Edirne, Turkey -- Ozkan, H., Uludag University, Faculty of Medicine, Bursa, Turkey -- Koksal, N., Uludag University, Faculty of Medicine, Bursa, Turkey -- Okulu, E., Van Training and Research Hospital, Van, Turkey -- Demir, N., Yuzuncu Yil University, School of Medicine, Van, Turkey -- Tuncer, O., Yuzuncu Yil University, School of Medicine, Van, Turkey -- Dizdar, E.A., Zekai Tahir Burak Maternity Teaching Hospital, Ankara, Turkey -- Oguz, S., Zekai Tahir Burak Maternity Teaching Hospital, Ankara, Turkey -- Dilmen, U., Zekai Tahir Burak Maternity Teaching Hospital, Ankara, Turkey, Hitit Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Alan, S, Erdeve, O, Cakir, U, Akduman, H, Zenciroglu, A, Akcakus, M, Tunc, T, Gokmen, Z, Ates, C, Atasay, B, Arsan, S, Sakarya Üniversitesi/Tıp Fakültesi/Dahili Tıp Bilimleri Bölümü, Caner, İbrahim, and Çukurova Üniversitesi

Subjects
Male, Pediatrics, Neonatal intensive care unit, Turkey, viruses, health care facilities, manpower, and services, respiratory syncytial virus, Infant, Newborn, Diseases, Disease Outbreaks, 0302 clinical medicine, newborn, Medicine, 030212 general & internal medicine, Prospective Studies, Neonatal Intensive Care Unit, Respiratory system, Prospective cohort study, Respiratory Tract Infections, Cross Infection, Respiratory tract infections, Incidence (epidemiology), Obstetrics and Gynecology, Obstetrics & Gynecology, Prognosis, Respiratory Syncytial Viruses, Hospitalization, Treatment Outcome, Female, medicine.drug, Palivizumab, medicine.medical_specialty, education, Respiratory Syncytial Virus Infections, Antiviral Agents, 03 medical and health sciences, 030225 pediatrics, Intensive care, Intensive Care Units, Neonatal, Humans, outbreak, business.industry, Infant, Newborn, Outbreak, Infant, nosocomial, Newborn, Pediatrics, Perinatology and Child Health, Respiratory Syncytial Virus, Nosocomial, business
Abstract

Taylor and Francis Ltd, Aim: To determine the incidence and outcomes of respiratory syncytial virus (RSV)-related acute lower respiratory tract infection (ALRI) including morbidity, nosocomial infection and mortality among newborn infants who were admitted to the neonatal intensive care units (NICUs).Methods: A multicenter, prospective study was conducted in newborns who were hospitalized with community acquired or nosocomial RSV infection in 44 NICUs throughout Turkey. Newborns with ALRI were screened for RSV infection by Respi-Strip®-test. Main outcome measures were the incidence of RSV-associated admissions in the NICUs and morbidity, mortality and epidemics results related to these admissions.Findings: The incidence of RSV infection was 1.24% (n: 250) and RSV infection constituted 19.6% of all ALRI hospitalizations, 226 newborns (90.4%) had community-acquired whereas 24 (9.6%) patients had nosocomial RSV infection in the NICUs. Of the 250 newborns, 171 (68.4%) were full-term infants, 183 (73.2%) had a BW >2500 g. RSV-related mortality rate was 1.2%. Four NICUs reported seven outbreaks on different months, which could be eliminated by palivizumab prophylaxis in one NICU.Conclusion: RSV-associated ALRI both in preterm and term infants accounts an important percent of hospitalizations in the season, and may threat other high-risk patients in the NICU. © 2015 Taylor & Francis., Alan, S.; Neonatal Intensive Care Unit, Hitit University Corum Training and Research Hospital, Vedat Dolakay Cad. No: 90A/16 Gaziosmanpasa, Turkey; email: alanserdar@gmail.com

Published
2016

24. Alışılmadık Jejunal Atrezi Tipi: Tip 1 Ve Tip 3a Karışımı

Author

GUNDUZ, Metin, CİFTCİ, İlhan, GOKMEN, Zeynel, and UNLU, Yasar

Subjects
Barsak atrezisi, lcsh:R, doğumsal anomaliler, lcsh:Medicine, Intestinal atresia, Congenital anomalies, Jejunoileal atresia, jejunoileal atrezi, Barsak atrezisi,doğumsal anomaliler,jejunoileal atrezi
Abstract

Intestinal atreziler yenidoğan barsak tıkanuklıklarının en sık sebebidir. Bu atrezilerin %46 sını Jejunoileal tıkanıklıklar oluşturur. Jejunoileal atreziler 4 tipe ayrılır. Olgumuz bu tiplerden hiçbirine uymamaktadır. Tip 1 ve Tip3a karışımı olarak tespit edilmiştir. Tespit ettiğimiz bu atrezide mucosal web yırtılarak açılmıştır. Intestinal atrezilerde cerrahi tedavi, erken ve doğru teşhis mortaliteyi, komplikasyonları azaltnaktadır. Sonuç olarak safralı kusma ile başvuran yenidoğanlarda intestinal atrezi hatırlanmalıdır. Bu atrezi normal tiplendirmeye uymayabilir., Intestinal atresias are a most common cause of bowel obstruction in the newborn. Jejunoileal obstruction was found in 46% of the intestinal atresia. The classification of jejunoileal atresias defined 4 types of lesions. Our case does not conform these types. A mixture of type I and type IIIa. This atresia included fenestrated mucosal web with minimal mesenteric defect. Being a life threatening surgical emergency, prompt diagnosis and opportune treatment are required to prevent mortality and other complications in intestinal atresias. In conclusion, intestinal atresias should be remembered in bilious vomiting of newborn. And intestinal atresia type may be unusual.

Published
2014

30. Outcome of the Respiratory Syncytial Virus related acute lower respiratory tract infection among hospitalized newborns: a prospective multicenter study.

Author

Alan, Serdar, Erdeve, Omer, Cakir, Ufuk, Akduman, Hasan, Zenciroglu, Aysegul, Akcakus, Mustafa, Tunc, Turan, Gokmen, Zeynel, Ates, Can, Atasay, Begum, and Arsan, Saadet

Subjects
RESPIRATORY syncytial virus infections, DISEASE incidence, HEALTH outcome assessment, RESPIRATORY infections, NOSOCOMIAL infections in children, NEONATAL diseases, DISEASE risk factors
Abstract

Aim: To determine the incidence and outcomes of respiratory syncytial virus (RSV)-related acute lower respiratory tract infection (ALRI) including morbidity, nosocomial infection and mortality among newborn infants who were admitted to the neonatal intensive care units (NICUs).Methods: A multicenter, prospective study was conducted in newborns who were hospitalized with community acquired or nosocomial RSV infection in 44 NICUs throughout Turkey. Newborns with ALRI were screened for RSV infection by Respi-Strip®-test. Main outcome measures were the incidence of RSV-associated admissions in the NICUs and morbidity, mortality and epidemics results related to these admissions.Findings: The incidence of RSV infection was 1.24% (n: 250) and RSV infection constituted 19.6% of all ALRI hospitalizations, 226 newborns (90.4%) had community-acquired whereas 24 (9.6%) patients had nosocomial RSV infection in the NICUs. Of the 250 newborns, 171 (68.4%) were full-term infants, 183 (73.2%) had a BW >2500 g. RSV-related mortality rate was 1.2%. Four NICUs reported seven outbreaks on different months, which could be eliminated by palivizumab prophylaxis in one NICU.Conclusion: RSV-associated ALRI both in preterm and term infants accounts an important percent of hospitalizations in the season, and may threat other high-risk patients in the NICU. [ABSTRACT FROM AUTHOR]

Published
2016
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31. Is umbilical cord milking always an advantage?

Author

Kilicdag, Hasan, Gulcan, Hande, Hanta, Deniz, Torer, Birgin, Gokmen, Zeynel, Ozdemir, Sonay Incesoy, and Antmen, Bulent Ali

Subjects
UMBILICAL cord, PREMATURE infants, NEUTROPHILS, NEUTROPENIA, INFANTS, COMPARATIVE studies, RESEARCH methodology, MEDICAL cooperation, POSTNATAL care, RESEARCH, STATISTICAL sampling, CYTOMETRY, EVALUATION research, RANDOMIZED controlled trials, PLATELET count
Abstract

Objective: The role of cord milking as an alternative to delayed cord clamping is an area that requires more research. Purpose of this clinical trial was to investigate the impact of umbilical cord milking on the absolute neutrophil counts (ANCs) and the neutropenia frequency of preterm infants.Methods: Fifty-eight pregnant women were randomly assigned to one of the umbilical cord milking and control groups. A total of 54 preterm infants (gestational age ≤ 32 weeks) were enrolled into the study. The umbilical cords of 25 infants were clamped immediately after birth, and in 29 infants, umbilical cord milking was performed first.Results: The ANCs were statistically significantly lower in the cord milking group compared with the control group on days 1, 3 and 7. The frequency of neutropenia was higher in the cord milking group compared with the control group.Conclusion: In our study, ANCs were lower in the cord milking group and the frequency of neutropenia was higher. Umbilical cord milking plays a role on the ANCs of preterm infants. [ABSTRACT FROM AUTHOR]

Published
2016
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42. Vestibular Evoked Myogenic Potentials in Preterm Infants.

Author

Erbek, Seyra, Gokmen, Zeynel, Ozkiraz, Servet, Erbek, Selim S., Tarcan, Aylin, and Ozluoglu, Levent N.

Subjects
*NEWBORN infant development, *PREMATURE infants, *PULMONARY manifestations of general diseases, *PHOTOTHERAPY, *HEMORRHAGE, *SEIZURES (Medicine), *SEPSIS
Abstract

The goal of this study was to determine whether there was an association between perinatal risk factors of prematurity and vestibular evoked myogenic potentials (VEMPs). A prospective case-control trial was designed. Fifty preterm newborns (100 ears) with a gestational age <37 weeks were included. The control group consisted of 20 healthy term infants (40 ears). VEMP recordings were performed, and mean latencies of p13 were calculated in all study subjects. Multivariable logistic regression was used to investigate the influence of perinatal variables on abnormal VEMP responses. VEMPs were elicited in all term infants (40 ears). In preterm infants, the responses were normal in 71 ears, delayed in 24 and absent in 5. There was a significant difference between abnormal VEMP rates for preterm and term infants (p < 0.001). Asphyxia (OR = 13.985, p = 0.048) and time of VEMP test (OR = 0.865, p = 0.038) were related to abnormal VEMP responses. There was no association between delayed VEMPs and gestational age, birth weight, hemoglobin and bilirubin levels, phototherapy, intracranial hemorrhage, convulsions, sepsis, ototoxic drugs, transfusion, mechanical ventilation, retinopathy of prematurity, bronchopulmonary dysplasia and respiratory distress syndrome. These results suggest a delay in the maturation of VEMPs in premature infants. Asphyxia was the most important risk factor for abnormal VEMP responses in preterm infants. Copyright © 2008 S. Karger AG, Basel [ABSTRACT FROM AUTHOR]

Published
2009
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43. Invasive Candida albicans infection mimicking leukemia in a neonate.

Author

Ozkiraz, Servet, Tarcan, Aylin, Gokmen, Zeynel, Gürakan, Berkan, Bilezikci, Banu, and Ozbek, Namik

Subjects
LEUKEMIA, ACUTE myeloid leukemia, CANCER, LEUCOCYTOSIS, ANEMIA
Abstract

Congenital leukemia is rare, and is frequently diagnosed as a form of acute myeloid leukemia at, or immediately after birth. Some infections, viral in particular, can mimic clinical signs and/or laboratory findings of congenital leukemia. This is the first documented case of candidemia resembling leukemia. [ABSTRACT FROM AUTHOR]

Published
2007
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44. Intravenous Immunoglobulin Use in Hemolytic Disease Due to ABO Incompatibility to Prevent Exchange Transfusion.

Author

Okulu E, Erdeve O, Kilic I, Olukman O, Calkavur S, Buyukkale G, Cetinkaya M, Ulubas D, Demirel N, Hanta D, Ertugrul S, Gultekin ND, Tuncer O, Demir N, Bilgin L, Narli N, Yildiz D, Terek D, Koroglu OA, Seren C, Ozyazici E, Ozdemir R, Turgut H, Narter F, Akin Y, Ozyazici A, Zenciroglu A, Asker HS, Gokmen Z, Salihli M, Bulbul A, Zubarioglu U, Atasay B, and Koc E

Abstract

Introduction: Intravenous immunoglobulin (IVIG) has been widely used to treat the hemolytic disease of the newborn (HDN). Although it has been shown that IVIG treatment reduces the duration of phototherapy and hospitalization, the use of IVIG in hemolytic disease due to ABO incompatibility has been controversial in recent years. This study aimed to investigate the role of IVIG in the prevention of exchange transfusion in infants with ABO HDN who presented with bilirubin levels at or above the level of exchange transfusion., Materials and Methods: This study evaluated the data of infants with ABO HDN in the Turkish Neonatal Jaundice Online Registry. The infants with ABO HDN who met the total serum bilirubin level inclusion criteria (within 2-3 mg/dL of exchange transfusion or even above exchange transfusion level) were included in the study according to the guidelines from the American Academy of Pediatrics and the Turkish Neonatal Society. All patients were managed according to the unit protocols recommended by these guidelines and received light-emitting diode (LED) phototherapy. Infants who only received LED phototherapy, and who received one dose of IVIG with LED phototherapy were compared., Results: During the study period, 531 term infants were included in the study according to inclusion criteria. There were 408 cases in the phototherapy-only group, and 123 cases in the IVIG group. The demographic findings and the mean bilirubin and reticulocyte levels at admission were similar between the groups ( p > 0.05), whereas the mean hemoglobin level was slightly lower in the IVIG group ( p = 0.037). The mean age at admission was earlier, the need for exchange transfusion was higher, and the duration of phototherapy was longer in the IVIG group ( p < 0.001, p = 0.001, and p < 0.001, respectively). The rate of re-hospitalization and acute bilirubin encephalopathy (ABE) was higher in the IVIG group ( p < 0.001 and p = 0.01, respectively)., Conclusion: In this study, we determined that one dose of IVIG did not prevent an exchange transfusion nor decrease the duration of phototherapy in infants, who had bilirubin levels near or at exchange transfusion level, with hemolytic disease due to ABO incompatibility., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2022 Okulu, Erdeve, Kilic, Olukman, Calkavur, Buyukkale, Cetinkaya, Ulubas, Demirel, Hanta, Ertugrul, Gultekin, Tuncer, Demir, Bilgin, Narli, Yildiz, Terek, Koroglu, Seren, Ozyazici, Ozdemir, Turgut, Narter, Akin, Ozyazici, Zenciroglu, Asker, Gokmen, Salihli, Bulbul, Zubarioglu, Atasay, Koc and Turkish Neonatal Society IVIG Study Group.)

Published
2022
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45. Discordant ROP (Retinopathy of prematurity) development in twins less than 32 weeks of gestational age.

Author

Silahli M, Tekin M, Kal A, Ulusoy MO, and Gokmen Z

Subjects
Birth Weight, Female, Gestational Age, Humans, Infant, Infant, Newborn, Infant, Premature, Retrospective Studies, Risk Factors, Twins, Retinopathy of Prematurity epidemiology, Retinopathy of Prematurity etiology
Abstract

Background and Aim: Retinopathy of prematurity (ROP), is a vasoprolipherative disorder of the immature retina and a major cause of preventable blindness in childhood. Although the development of ROP is multifactorial, the main reasons are lower gestational age and birth weight. However, in twins their gestational ages were the same, ROP development can be discordant. This study aims to evaluate the etiologic factors of discordant ROP development in twins., Methods: We reviewed the last 5 years' records and found the twins whose discordant ROP development. This discordance was; 1. Different stages of ROP, 2. One sibling treated the other is not, 3. One sibling has aggressive posterior ROP the other is not, 4. one sibling has more influenced area as zones the other is not. We documented some data of these twins, as birth order, birth weight, resuscitation at birth, morbidities, the number of hemotransfusion, age of regaining birth weight, relative weight gain at 28 weeks., Results: A total of 26 cases of 13 twins were evaluated. The mean gestational age and birth weight of the whole study group were 27.7 ± 2, and 1053 ±  364 grams, respectively. We found that more transfused preterm baby in twins is more likely to show severe ROP. Additionally, sepsis and the duration of mechanical ventilation may be risk factors for more severe ROP in twins., Conclusions: We can reduce discordant retinopathy in less than 32-weeks premature twins by using methods such as cord milking and by improving non-invasive ventilation modalities.

Published
2022
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46. The relationship between placental transfusion, and thymic size and neonatal morbidities in premature infants - A Randomized Control Trial

Author

Silahli M, Duman E, Gokmen Z, Toprak E, Gokdemir M, and Ecevit A

Subjects
Constriction, Double-Blind Method, Female, Follow-Up Studies, Humans, Infant, Infant Mortality trends, Infant, Newborn, Infant, Premature, Diseases mortality, Morbidity trends, Organ Size, Placenta, Pregnancy, Prospective Studies, Time Factors, Turkey epidemiology, Umbilical Cord, Blood Transfusion methods, Infant, Premature, Infant, Premature, Diseases therapy, Thymus Gland diagnostic imaging
Abstract

Objective: To compare the effect of umbilical cord milking and early cord clamping on thymic size, and neonatal mortality and morbidity in preterm infants., Methods: This single-center, prospective, double-blind, randomised controlled study was conducted at Baskent University, Konya Education and Research Centre, Konya, Turkey, between October 2015 and April 2016. Pregnant women who delivered before 32 weeks of gestation were randomised to receive umbilical cord milking (group 1) or early cord clamping (group 2). Ultrasonographic evaluation was performed in each newborn by an experienced radiologist within the first 24 hours of life. Thymic si ze was estimated in l ine with literatu re. SPSS 15 was u sed for a ll data analyses., Results: There were 38 subjects in group 1 and 37 in group 2. There were as many infants in the two groups (p>0.05) The haemoglobin levels was higher in group 1, but not significantly (p=0.213). The absolute neutrophil count in group 1 was significantly lower (p= 0.017) than group 2. In terms of neonatal mortaility and morbidity, there were no significant differences between the groups (p>0.05)., Conclusions: Umbilical cord milking was not associated with thymic size during the the first 24h of life.

Published
2018

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