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1. Behandlung von schädlichem und abhängigem Tabakkonsum

Author

Andreas, Stefan, Batra, Anil, Brüggmann, Dörthe, Geyer, Dieter, Gohlke, Helmut, Hering, Thomas, Jähne, Andreas, Jückstock, Julia, Klein, Marianne, Kotz, Daniel, Kröger, Christoph, Krüger, Timo, Kölch, Michael, Lesta, Evelyn, Lindenmeyer, Johannes, Lindinger, Peter, Mons, Ute, Mühlig, Stephan, Neumann, Tim, Petersen, Kay Uwe, Polak, Thomas, Preuss, Ulrich W., Pötschke-Langer, Martina, Rustler, Christa, Rüther, Tobias, Schiller, Sophie Luise, Schwarz, Christiane, Schweizer, Cornelie, Thomasius, Rainer, Ulbricht, Sabina, Veltrup, Clemens, Batra, Anil, editor, Petersen, Kay Uwe, editor, Kiefer, Falk, editor, and Hoffmann, Sabine, editor

Published
2022
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3. Coronary computed tomography angiography (CCTA) in patients with suspected stable coronary artery disease (CAD): diagnostic impact and clinical consequences in the German Cardiac CT Registry depending on stress test results

Author

Barth, Sebastian, Marwan, Mohamed, Hausleiter, Jörg, Moshage, Werner, Korosoglou, Grigorios, Leber, Alexander, Schmermund, Axel, Gohlke, Helmut, Bruder, Oliver, Dill, Thorsten, Schröder, Stephen, Kerber, Sebastian, Hamm, Karsten, Gietzen, Frank, Schneider, Steffen, Senges, Jochen, and Achenbach, Stephan

Published
2019
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4. Behandlung von schädlichem und abhängigem Tabakkonsum

Author

Batra, Anil, Andreas, Stefan, Bartsch, Gabriele, Gohlke, Helmut, Jähne, Andreas, Kröger, Christoph, Lindinger, Peter, Mühlig, Stephan, Neumann, Tim, Pötschke-Langer, Martina, Ratje, Ulf, Rüther, Tobias, Schweizer, Cornelie, Thürauf, Norbert, Ulbricht, Sabina, Petersen, Kay Uwe, Batra, Anil, editor, Hoch, Eva, editor, Mann, Karl, editor, and Petersen, Kay Uwe, editor

Published
2015
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5. Exercise Training in Coronary Heart Disease

Author

Gohlke, Helmut, Perk, Joep, editor, Gohlke, Helmut, editor, Hellemans, Irene, editor, Sellier, Philippe, editor, Mathes, Peter, editor, Monpère, Catherine, editor, McGee, Hannah, editor, and Saner, Hugo, editor

Published
2007
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8. S3 Guideline Smoking and Tobacco Dependence: Screening, Diagnosis, and Treatment - Short Version

Author

Batra, Anil, Kiefer, Falk, Andreas, Stefan, Gohlke, Helmut, Klein, Marianne, Kotz, Daniel, Mons, Ute, Muehlig, Stephan, Poetschke-Langer, Martina, Preuss, Ulrich W., Ruether, Tobias, Rustler, Christa, Thomasius, Rainer, Ulbricht, Sabina, Petersen, Kay Uwe, Batra, Anil, Kiefer, Falk, Andreas, Stefan, Gohlke, Helmut, Klein, Marianne, Kotz, Daniel, Mons, Ute, Muehlig, Stephan, Poetschke-Langer, Martina, Preuss, Ulrich W., Ruether, Tobias, Rustler, Christa, Thomasius, Rainer, Ulbricht, Sabina, and Petersen, Kay Uwe

Abstract

Introduction: In addition to the prevention of tobacco consumption, the establishment and assurance of high-quality treatment for harmful use and dependence on tobacco products remains an important health-related task in Germany. Regular updating of the Association of the Scientific Medical Societies (AWMF) S3 guideline Smoking and Tobacco Dependence: Screening, Diagnosis, and Treatment (Tobacco Guideline) offers a sustainable and reputable source of knowledge on smoking cessation. Methods: Under the auspices of the German Society for Psychiatry, Psychotherapy, Psychosomatics, and Neurology (DGPPN) and the German Society for Addiction Research and Addiction Therapy (DG-Sucht), the Tobacco Guideline was revised in 2019-2020 by 63 experts, who were involved in the development process of the text, in 11 working groups. Undue influence of conflicts of interest on the guideline could be minimized through careful conflict of interest management. Delegates from 50 professional societies discussed the 80 guideline recommendations and voted online. Results: In addition to recommendations for screening and diagnostics, the Tobacco Guideline takes a positive stance towards the use of low-threshold counseling and support services. If, due to the severity of the tobacco-related disorder, brief counseling, telephone counseling, or internet- or smartphone-based methods are not sufficiently effective, individual or group behavioral therapy, possibly in combination with medication, is indicated. If nicotine replacement therapy is not effective, varenicline or bupropion should be offered. Alternative strategies with a lower level of recommendation are hypnotherapy, mindfulness-based treatments, or medication with cytisine. In adolescents and pregnant women, the use of medication should be limited to well-specified exceptions and nicotine replacement. The mean agreement with the recommendations reached a value of 98%. A general overview of the treatment recommendations of the Tobacco

Published
2022

10. S3 Guideline “Smoking and Tobacco Dependence: Screening, Diagnosis, and Treatment” – Short Version

Author

Batra, Anil, primary, Kiefer, Falk, additional, Andreas, Stefan, additional, Gohlke, Helmut, additional, Klein, Marianne, additional, Kotz, Daniel, additional, Mons, Ute, additional, Mühlig, Stephan, additional, Pötschke-Langer, Martina, additional, Preuss, Ulrich W., additional, Rüther, Tobias, additional, Rustler, Christa, additional, Thomasius, Rainer, additional, Ulbricht, Sabina, additional, and Petersen, Kay Uwe, additional

Published
2022
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12. Cardiac Rehabilitation in German Speaking Countries of Europe—Evidence-Based Guidelines from Germany, Austria and Switzerland LLKardReha-DACH—Part 2

Author

Schwaab, Bernhard, primary, Bjarnason-Wehrens, Birna, additional, Meng, Karin, additional, Albus, Christian, additional, Salzwedel, Annett, additional, Schmid, Jean-Paul, additional, Benzer, Werner, additional, Metz, Matthes, additional, Jensen, Katrin, additional, Rauch, Bernhard, additional, Bönner, Gerd, additional, Brzoska, Patrick, additional, Buhr-Schinner, Heike, additional, Charrier, Albrecht, additional, Cordes, Carsten, additional, Dörr, Gesine, additional, Eichler, Sarah, additional, Exner, Anne-Kathrin, additional, Fromm, Bernd, additional, Gielen, Stephan, additional, Glatz, Johannes, additional, Gohlke, Helmut, additional, Grilli, Maurizio, additional, Gysan, Detlef, additional, Härtel, Ursula, additional, Hahmann, Harry, additional, Herrmann-Lingen, Christoph, additional, Karger, Gabriele, additional, Karoff, Marthin, additional, Kiwus, Ulrich, additional, Knoglinger, Ernst, additional, Krusch, Christian-Wolfgang, additional, Langheim, Eike, additional, Mann, Johannes, additional, Max, Regina, additional, Metzendorf, Maria-Inti, additional, Nebel, Roland, additional, Niebauer, Josef, additional, Predel, Hans-Georg, additional, Preßler, Axel, additional, Razum, Oliver, additional, Reiss, Nils, additional, Saure, Daniel, additional, von Schacky, Clemens, additional, Schütt, Morten, additional, Schultz, Konrad, additional, Skoda, Eva-Maria, additional, Steube, Diethard, additional, Streibelt, Marco, additional, Stüttgen, Martin, additional, Stüttgen, Michaela, additional, Teufel, Martin, additional, Tschanz, Hansueli, additional, Völler, Heinz, additional, Vogel, Heiner, additional, and Westphal, Ronja, additional

Published
2021
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13. Cardiac Rehabilitation in German Speaking Countries of Europe-Evidence-Based Guidelines from Germany, Austria and Switzerland LLKardReha-DACH-Part 2

Author

Schwaab, Bernhard, Bjarnason-Wehrens, Birna, Meng, Karin, Albus, Christian, Salzwedel, Annett, Schmid, Jean-Paul, Benzer, Werner, Metz, Matthes, Jensen, Katrin, Rauch, Bernhard, Boenner, Gerd, Brzoska, Patrick, Buhr-Schinner, Heike, Charrier, Albrecht, Cordes, Carsten, Doerr, Gesine, Eichler, Sarah, Exner, Anne-Kathrin, Fromm, Bernd, Gielen, Stephan, Glatz, Johannes, Gohlke, Helmut, Grilli, Maurizio, Gysan, Detlef, Haertel, Ursula, Hahmann, Harry, Herrmann-Lingen, Christoph, Karger, Gabriele, Karoff, Marthin, Kiwus, Ulrich, Knoglinger, Ernst, Krusch, Christian-Wolfgang, Langheim, Eike, Mann, Johannes, Max, Regina, Metzendorf, Maria-Inti, Nebel, Roland, Niebauer, Josef, Predel, Hans-Georg, Pressler, Axel, Razum, Oliver, Reiss, Nils, Saure, Daniel, von Schacky, Clemens, Schuett, Morten, Schultz, Konrad, Skoda, Eva-Maria, Steube, Diethard, Streibelt, Marco, Stuettgen, Martin, Stuettgen, Michaela, Teufel, Martin, Tschanz, Hansueli, Voeller, Heinz, Vogel, Heiner, Westphal, Ronja, Schwaab, Bernhard, Bjarnason-Wehrens, Birna, Meng, Karin, Albus, Christian, Salzwedel, Annett, Schmid, Jean-Paul, Benzer, Werner, Metz, Matthes, Jensen, Katrin, Rauch, Bernhard, Boenner, Gerd, Brzoska, Patrick, Buhr-Schinner, Heike, Charrier, Albrecht, Cordes, Carsten, Doerr, Gesine, Eichler, Sarah, Exner, Anne-Kathrin, Fromm, Bernd, Gielen, Stephan, Glatz, Johannes, Gohlke, Helmut, Grilli, Maurizio, Gysan, Detlef, Haertel, Ursula, Hahmann, Harry, Herrmann-Lingen, Christoph, Karger, Gabriele, Karoff, Marthin, Kiwus, Ulrich, Knoglinger, Ernst, Krusch, Christian-Wolfgang, Langheim, Eike, Mann, Johannes, Max, Regina, Metzendorf, Maria-Inti, Nebel, Roland, Niebauer, Josef, Predel, Hans-Georg, Pressler, Axel, Razum, Oliver, Reiss, Nils, Saure, Daniel, von Schacky, Clemens, Schuett, Morten, Schultz, Konrad, Skoda, Eva-Maria, Steube, Diethard, Streibelt, Marco, Stuettgen, Martin, Stuettgen, Michaela, Teufel, Martin, Tschanz, Hansueli, Voeller, Heinz, Vogel, Heiner, and Westphal, Ronja

Abstract

Background: Scientific guidelines have been developed to update and harmonize exercise based cardiac rehabilitation (ebCR) in German speaking countries. Key recommendations for ebCR indications have recently been published in part 1 of this journal. The present part 2 updates the evidence with respect to contents and delivery of ebCR in clinical practice, focusing on exercise training (ET), psychological interventions (PI), patient education (PE). In addition, special patients' groups and new developments, such as telemedical (Tele) or home-based ebCR, are discussed as well. Methods: Generation of evidence and search of literature have been described in part 1. Results: Well documented evidence confirms the prognostic significance of ET in patients with coronary artery disease. Positive clinical effects of ET are described in patients with congestive heart failure, heart valve surgery or intervention, adults with congenital heart disease, and peripheral arterial disease. Specific recommendations for risk stratification and adequate exercise prescription for continuous-, interval-, and strength training are given in detail. PI when added to ebCR did not show significant positive effects in general. There was a positive trend towards reduction in depressive symptoms for distress management and lifestyle changes. PE is able to increase patients' knowledge and motivation, as well as behavior changes, regarding physical activity, dietary habits, and smoking cessation. The evidence for distinct ebCR programs in special patients' groups is less clear. Studies on Tele-CR predominantly included low-risk patients. Hence, it is questionable, whether clinical results derived from studies in conventional ebCR may be transferred to Tele-CR. Conclusions: ET is the cornerstone of ebCR. Additional PI should be included, adjusted to the needs of the individual patient. PE is able to promote patients self-management, empowerment, and motivation. Diversity-sensitive structures should b

Published
2021

14. German Guideline for Smoking and Tobacco Dependence: Screening, Diagnosis and Treatment, Update 2021 - Short Version

Author

Batra, Anil, Kiefer, Falk, Andreas, Stefan, Gohlke, Helmut, Klein, Marianne, Kotz, Daniel, Mons, Ute, Muehlig, Stephan, Poetschke-Langer, Martina, Preuss, Ulrich W., Ruether, Tobias, Rustler, Christa, Thomasius, Rainer, Ulbricht, Sabina, Petersen, Kay Uwe, Batra, Anil, Kiefer, Falk, Andreas, Stefan, Gohlke, Helmut, Klein, Marianne, Kotz, Daniel, Mons, Ute, Muehlig, Stephan, Poetschke-Langer, Martina, Preuss, Ulrich W., Ruether, Tobias, Rustler, Christa, Thomasius, Rainer, Ulbricht, Sabina, and Petersen, Kay Uwe

Abstract

Introduction: In addition to the prevention of tobacco consumption, the establishment and assurance of high-quality treatment for harmful use and dependance on tobacco products remains an important health-related task in Germany. Regular updating of the AWMF-S3Guideline,Smoking and Tobacco Dependence: Screening, Diagnosis and Treatment (Tobacco Guideline) offers a sustainable and reputable source of knowledge on smoking cessation. Methods: Under the auspices of the German Society for Psychiatry, Psychotherapy, Psychosomatics and Neurology (DGPPN) and the German Society for Addiction Research and Addiction Therapy (DG-Sucht), the Tobacco Guideline was revised in 2019-2020 by 63 people, who were involved in the development process of the text, in 11 working groups. Through careful COI management, the influence of conflicts of interest could be minimised. Delegates from 50 professional societies discussed the 80 guideline recommendations and voted online. Results: In addition to recommendations for screening and diagnostics, the Tobacco Guideline takes a positive stance towards the use of low-threshold counselling and support services. If, due to the severity of the tobacco-related disorder, brief counselling, telephone counselling or internet- or smartphone-based methods are not sufficiently effective, individual or group behavioural therapy, possibly in combination with medication, is indicated. If nicotine replacement therapy is not effective, varenicline or bupropion should be offered. Alternative strategies with a lower level of recommendation are hypnotherapy, mindfulness-based treatments or cytisine. In adolescents and pregnant women, the use of medication should be limited to well-specified exceptions and nicotine replacement. The mean agreement with the recommendations reaches a value of 98 %. A general overview of the treatment recommendations of the Tobacco Guideline is provided by three clinical algorithms.

Published
2021

16. S3-Leitlinie „Rauchen und Tabakabhängigkeit: Screening, Diagnostik und Behandlung“

Author

Batra, Anil, primary, Kiefer, Falk, additional, Andreas, Stefan, additional, Gohlke, Helmut, additional, Klein, Marianne, additional, Kotz, Daniel, additional, Mons, Ute, additional, Mühlig, Stephan, additional, Pötschke-Langer, Martina, additional, Preuss, Ulrich W., additional, Rüther, Tobias, additional, Rustler, Christa, additional, Thomasius, Rainer, additional, Ulbricht, Sabina, additional, and Petersen, Kay Uwe, additional

Published
2021
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24. 2019 ESC Guidelines for the diagnosis and management of chronic coronary syndromes

Author

Neumann, Franz Josef, Sechtem, Udo, Banning, Adrian Paul, Bonaros, Nikolaos, Bueno, Héctor, Bugiardini, Raffaele, Chieffo, Alaide, Crea, Filippo, Czerny, Martin, Delgado, Victoria, Dendale, Paul, Knuuti, Juhani, Wijns, William, Flachskampf, Frank Arnold, Gohlke, Helmut, Grove, Erik Lerkevang, James, Stefan, Katritsis, Demosthenes, Landmesser, Ulf, Lettino, Maddalena, Matter, Christian M., Nathoe, Hendrik, Niessner, Alexander, Patrono, Carlo, Petronio, Anna Sonia, Pettersen, Steffen E., Piccolo, Raffaele, Piepoli, Massimo Francesco, Popescu, Bogdan A., Räber, Lorenz, Richter, Dimitrios J., Roffi, Marco, Roithinger, Franz X., Shlyakhto, Evgeny, Sibbing, Dirk, Silber, Sigmund, Simpson, Iain A., Sousa-Uva, Miguel, Vardas, Panos, Witkowski, Adam, Zamorano, Jose Luis, Achenbach, Stephan, Agewall, Stefan, Barbato, Emanuele, Bax, Jeroen J., Capodanno, Davide, Cuisset, Thomas, Deaton, Christi, Dickstein, Kenneth, Edvardsen, Thor, Escaned, Javier, Funck-Brentano, Christian, Gersh, Bernard J., Gilard, Martine, Hasdai, David, Hatala, Robert, Mahfoud, Felix, Masip, Josep, Muneretto, Claudio, Prescott, Eva, Saraste, Antti, Storey, Robert F., Svitil, Pavel, Valgimigli, Marco, Aboyans, Victor, Baigent, Colin, Collet, Jean Philippe, Dean, Veronica, Fitzsimons, Donna, Gale, Christopher P., Grobbee, Diederick E., Halvorsen, Sigrun, Hindricks, Gerhard, Iung, Bernard, Jüni, Peter, Katus, Hugo A., Leclercq, Christophe, Lewis, Basil S., Merkely, Bela, Mueller, Christian, Petersen, Steffen, Touyz, Rhian M., Benkhedda, Salim, Metzler, Bernhard, Sujayeva, Volha, Cosyns, Bernard, Kusljugic, Zumreta, Velchev, Vasil, Panayi, Georgios, Kala, Petr, Haahr-Pedersen, Sune Ammentorp, Kabil, Hamza, Ainla, Tiia, Kaukonen, Tomi, Cayla, Guillaume, Pagava, Zurab, Woehrle, Jochen, Kanakakis, John, Toth, Kalman, Gudnason, Thorarinn, Peace, Aaron, Aronson, Doron, Riccio, Carmine, Elezi, Shpend, Mirrakhimov, Erkin, Hansone, Silvija, Sarkis, Antoine, Babarskiene, Ruta, Beissel, Jean, Cassar Maempel, Andrew J., Revenco, Valeriu, de Grooth, G. J., Pejkov, Hristo, Juliebø, Vibeke, Lipiec, Piotr, Santos, Jose, Chioncel, Ovidiu, Duplyakov, Dmitry, Bertelli, Luca, Dikic, Ana Djordjevic, Studencan, Martin, Bunc, Matjaz, Alfonso, Fernando, Back, Magnus, Zellweger, Michael, Addad, Faouzi, Yildirir, Aylin, Sirenko, Yuriy, Clapp, Brian, Neumann, Franz Josef, Sechtem, Udo, Banning, Adrian Paul, Bonaros, Nikolaos, Bueno, Héctor, Bugiardini, Raffaele, Chieffo, Alaide, Crea, Filippo, Czerny, Martin, Delgado, Victoria, Dendale, Paul, Knuuti, Juhani, Wijns, William, Flachskampf, Frank Arnold, Gohlke, Helmut, Grove, Erik Lerkevang, James, Stefan, Katritsis, Demosthenes, Landmesser, Ulf, Lettino, Maddalena, Matter, Christian M., Nathoe, Hendrik, Niessner, Alexander, Patrono, Carlo, Petronio, Anna Sonia, Pettersen, Steffen E., Piccolo, Raffaele, Piepoli, Massimo Francesco, Popescu, Bogdan A., Räber, Lorenz, Richter, Dimitrios J., Roffi, Marco, Roithinger, Franz X., Shlyakhto, Evgeny, Sibbing, Dirk, Silber, Sigmund, Simpson, Iain A., Sousa-Uva, Miguel, Vardas, Panos, Witkowski, Adam, Zamorano, Jose Luis, Achenbach, Stephan, Agewall, Stefan, Barbato, Emanuele, Bax, Jeroen J., Capodanno, Davide, Cuisset, Thomas, Deaton, Christi, Dickstein, Kenneth, Edvardsen, Thor, Escaned, Javier, Funck-Brentano, Christian, Gersh, Bernard J., Gilard, Martine, Hasdai, David, Hatala, Robert, Mahfoud, Felix, Masip, Josep, Muneretto, Claudio, Prescott, Eva, Saraste, Antti, Storey, Robert F., Svitil, Pavel, Valgimigli, Marco, Aboyans, Victor, Baigent, Colin, Collet, Jean Philippe, Dean, Veronica, Fitzsimons, Donna, Gale, Christopher P., Grobbee, Diederick E., Halvorsen, Sigrun, Hindricks, Gerhard, Iung, Bernard, Jüni, Peter, Katus, Hugo A., Leclercq, Christophe, Lewis, Basil S., Merkely, Bela, Mueller, Christian, Petersen, Steffen, Touyz, Rhian M., Benkhedda, Salim, Metzler, Bernhard, Sujayeva, Volha, Cosyns, Bernard, Kusljugic, Zumreta, Velchev, Vasil, Panayi, Georgios, Kala, Petr, Haahr-Pedersen, Sune Ammentorp, Kabil, Hamza, Ainla, Tiia, Kaukonen, Tomi, Cayla, Guillaume, Pagava, Zurab, Woehrle, Jochen, Kanakakis, John, Toth, Kalman, Gudnason, Thorarinn, Peace, Aaron, Aronson, Doron, Riccio, Carmine, Elezi, Shpend, Mirrakhimov, Erkin, Hansone, Silvija, Sarkis, Antoine, Babarskiene, Ruta, Beissel, Jean, Cassar Maempel, Andrew J., Revenco, Valeriu, de Grooth, G. J., Pejkov, Hristo, Juliebø, Vibeke, Lipiec, Piotr, Santos, Jose, Chioncel, Ovidiu, Duplyakov, Dmitry, Bertelli, Luca, Dikic, Ana Djordjevic, Studencan, Martin, Bunc, Matjaz, Alfonso, Fernando, Back, Magnus, Zellweger, Michael, Addad, Faouzi, Yildirir, Aylin, Sirenko, Yuriy, and Clapp, Brian

Abstract

Coronary artery disease (CAD) is a pathological process characterized by atherosclerotic plaque accumulation in the epicardial arteries, whether obstructive or non-obstructive. This process can be modified by lifestyle adjustments, pharmacological therapies, and invasive interventions designed to achieve disease stabilization or regression. The disease can have long, stable periods but can also become unstable at any time, typically due to an acute atherothrombotic event caused by plaque rupture or erosion. However, the disease is chronic, most often progressive, and hence serious, even in clinically apparently silent periods. The dynamic nature of the CAD process results in various clinical presentations, which can be conveniently categorized as either acute coronary syndromes (ACS) or chronic coronary syndromes (CCS). The Guidelines presented here refer to the management of patients with CCS. The natural history of CCS is illustrated in Figure 1.

Published
2020

30. European Guidelines on cardiovascular disease prevention in clinical practice (version 2012): The Fifth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of nine societies and by invited experts)

Author

Perk, Joep, De Backer, Guy, Gohlke, Helmut, Graham, Ian, Reiner, Željko, Verschuren, Monique WM, Albus, Christian, Benlian, Pascale, Boysen, Gudrun, Cifkova, Renata, Deaton, Christi, Ebrahim, Shah, Fisher, Miles, Germano, Giuseppe, Hobbs, Richard, Hoes, Arno, Karadeniz, Sehnaz, Mezzani, Alessandro, Prescott, Eva, Ryden, Lars, Scherer, Martin, Syvänne, Mikko, Scholte Op Reimer, Wilma JM, Vrints, Christiaan, Wood, David, Zamorano, Jose Luis, and Zannad, Faiez

Published
2012
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31. †Guidelines on diabetes, pre-diabetes, and cardiovascular diseases: executive summary: The Task Force on Diabetes and Cardiovascular Diseases of the European Society of Cardiology (ESC) and of the European Association for the Study of Diabetes (EASD)

Author

Rydén, Lars, Standl, Eberhard, Bartnik, Małgorzata, Van den Berghe, Greet, Betteridge, John, de Boer, Menko-Jan, Cosentino, Francesco, Jönsson, Bengt, Laakso, Markku, Malmberg, Klas, Priori, Silvia, Östergren, Jan, Tuomilehto, Jaakko, Thrainsdottir, Inga, Vanhorebeek, Ilse, Stramba-Badiale, Marco, Lindgren, Peter, Qiao, Qing, Priori, Silvia G., Blanc, Jean-Jacques, Budaj, Andrzej, Camm, John, Dean, Veronica, Deckers, Jaap, Dickstein, Kenneth, Lekakis, John, McGregor, Keith, Metra, Marco, Morais, João, Osterspey, Ady, Tamargo, Juan, Zamorano, José Luis, Deckers, Jaap W., Bertrand, Michel, Charbonnel, Bernard, Erdmann, Erland, Ferrannini, Ele, Flyvbjerg, Allan, Gohlke, Helmut, Juanatey, Jose Ramon Gonzalez, Graham, Ian, Monteiro, Pedro Filipe, Parhofer, Klaus, Pyörälä, Kalevi, Raz, Itamar, Schernthaner, Guntram, Volpe, Massimo, and Wood, David

Published
2007

32. Recomendações Europeias para a prevenção da doença cardiovascular na prática clínica (versão de 2012)

Author

Perk, Joep, Backer, Guy De, Gohlke, Helmut, Graham, Ian, Reiner, Zeljko, Verschuren, W.M. Monique, Albus, Christian, Benlian, Pascale, Boysen, Gudrun, Cifkova, Renata, Deaton, Christi, Ebrahim, Shah, Fisher, Miles, Germano, Giuseppe, Hobbs, Richard, Hoes, Arno, Karadeniz, Sehnaz, Mezzani, Alessandro, Prescott, Eva, Ryden, Lars, Scherer, Martin, Syvänne, Mikko, Reimer, Wilma J.M. Scholte Op, Vrints, Christiaan, Wood, David, Zamorano, Jose Luis, and Zannad, Faiez

Published
2013
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33. European Guidelines on cardiovascular disease prevention in clinical practice (version 2012)

Author

Perk, Joep, Backer, Guy De, Gohlke, Helmut, Graham, Ian, Reiner, Zeljko, Verschuren, W.M. Monique, Albus, Christian, Benlian, Pascale, Boysen, Gudrun, Cifkova, Renata, Deaton, Christi, Ebrahim, Shah, Fisher, Miles, Germano, Giuseppe, Hobbs, Richard, Hoes, Arno, Karadeniz, Sehnaz, Mezzani, Alessandro, Prescott, Eva, Ryden, Lars, Scherer, Martin, Syvänne, Mikko, Reimer, Wilma J.M. Scholte Op, Vrints, Christiaan, Wood, David, Zamorano, Jose Luis, and Zannad, Faiez

Published
2013
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34. Coronary computed tomography angiography (CCTA) in patients with suspected stable coronary artery disease (CAD): diagnostic impact and clinical consequences in the German Cardiac CT Registry depending on stress test results

Author

Barth, Sebastian, primary, Marwan, Mohamed, additional, Hausleiter, Jörg, additional, Moshage, Werner, additional, Korosoglou, Grigorios, additional, Leber, Alexander, additional, Schmermund, Axel, additional, Gohlke, Helmut, additional, Bruder, Oliver, additional, Dill, Thorsten, additional, Schröder, Stephen, additional, Kerber, Sebastian, additional, Hamm, Karsten, additional, Gietzen, Frank, additional, Schneider, Steffen, additional, Senges, Jochen, additional, and Achenbach, Stephan, additional

Published
2018
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36. Substantial improvement of primary cardiovascular prevention by a systematic score-based multimodal approach: A randomized trial: The PreFord-Study

Author

Gysan, Detlef Bernd, Millentrup, Stefanie, Albus, Christian, Bjarnason-Wehrens, Birna, Latsch, Joachim, Gohlke, Helmut, Herold, Gerd, Wegscheider, Karl, Heming, Christian, Seyfarth, Melchior, Predel, Hans-Georg, Gysan, Detlef Bernd, Millentrup, Stefanie, Albus, Christian, Bjarnason-Wehrens, Birna, Latsch, Joachim, Gohlke, Helmut, Herold, Gerd, Wegscheider, Karl, Heming, Christian, Seyfarth, Melchior, and Predel, Hans-Georg

Abstract

Trial design Prospective randomized multicentre interventional study. Methods Individual cardiovascular risk assessment in Ford Company, Germany employees (n=4.196), using the European Society of Cardiology-Systematic Coronary Risk Evaluation (ESC-SCORE) for classification into three risk groups. Subjects assigned to ESC high-risk group (ESC-SCORE5%), without a history of cardiovascular disease were eligible for randomization to a multimodal 15-week intervention programme (INT) or to usual care and followed up for 36 months. Objectives Evaluation of the long-term effects of a risk-adjusted multimodal intervention in high-risk subjects. Primary endpoint: reduction of ESC-SCORE in INT versus usual care. Secondary endpoints: composite of fatal and non-fatal cardiovascular events and time to first cardiovascular event. Statistical analysis: intention-to-treat and per-protocol analysis. Results Four hundred and forty-seven subjects were randomized to INT (n=224) or to usual care (n=223). After 36 months ESC-SCORE development favouring INT was observed (INT: 8.70% to 10.03% vs. usual care: 8.49% to 12.09%; p=0.005; net difference: 18.50%). Moreover, a significant reduction in the composite cardiovascular events was observed: (INT: n=11 vs. usual care: n=27). Hazard ratio of intervention versus control was 0.51 (95% confidence interval 0.25-1.03; p=0.062) in the intention-to-treat analysis and 0.41 (95% confidence interval 0.18-0.90; p=0.026) in the per-protocol analysis, respectively. No intervention-related adverse events or side-effects were observed. Conclusions Our results demonstrate the efficiency of identifying cardiovascular high-risk subjects by the ESC-SCORE in order to enrol them to a risk adjusted primary prevention programme. This strategy resulted in a significant improvement of ESC-SCORE, as well as a reduction in predefined cardiovascular endpoints in the INT within 36 months. (ISRCTN 23536103.)

Published
2017

38. Substantial improvement of primary cardiovascular prevention by a systematic score-based multimodal approach: A randomized trial: The PreFord-Study

Author

Gysan, Detlef Bernd, primary, Millentrup, Stefanie, additional, Albus, Christian, additional, Bjarnason-Wehrens, Birna, additional, Latsch, Joachim, additional, Gohlke, Helmut, additional, Herold, Gerd, additional, Wegscheider, Karl, additional, Heming, Christian, additional, Seyfarth, Melchior, additional, and Predel, Hans-Georg, additional

Published
2017
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41. S3-Leitlinie „Screening, Diagnostik und Behandlung des schädlichen und abhängigen Tabakkonsums“

Author

Batra, Anil, primary, Petersen, Kay Uwe, additional, Hoch, Eva, additional, Andreas, Stefan, additional, Bartsch, Gabriele, additional, Gohlke, Helmut, additional, Jähne, Andreas, additional, Kröger, Christoph, additional, Lindinger, Peter, additional, Mühlig, Stephan, additional, Neumann, Tim, additional, Pötschke-Langer, Martina, additional, Ratje, Ulf, additional, Rüther, Tobias, additional, Schweizer, Cornelie, additional, Thürauf, Norbert, additional, Ulbricht, Sabina, additional, and Mann, Karl, additional

Published
2016
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42. S3 Guideline “Screening, Diagnostics, and Treatment of Harmful and Addictive Tobacco Use”

Author

Batra, Anil, primary, Petersen, Kay Uwe, additional, Hoch, Eva, additional, Andreas, Stefan, additional, Bartsch, Gabriele, additional, Gohlke, Helmut, additional, Jähne, Andreas, additional, Kröger, Christoph, additional, Lindinger, Peter, additional, Mühlig, Stephan, additional, Neumann, Tim, additional, Pötschke-Langer, Martina, additional, Ratje, Ulf, additional, Rüther, Tobias, additional, Schweizer, Cornelie, additional, Thürauf, Norbert, additional, Ulbricht, Sabina, additional, and Mann, Karl, additional

Published
2016
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43. Abstract 17097: Substantial Improvement of Primary Cardiovascular Prevention by a Systematic Score-based Multimodal and Lifestyle Approach: A Randomized Endpoint-Study - The Preford-Study

Author

Predel, Hans Georg, primary, Gysan, Detlef B, additional, Albus, Christian, additional, Bjarnason-Wehrens, Birna, additional, Gohlke, Helmut, additional, Latsch, Joachim, additional, Millentrup, Stefanie, additional, Heming, Christian, additional, and Herold, Gerd, additional

Published
2015
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44. European Guidelines on Cardiovascular Diseases prevention in clinical practice (version 2012)

Author

Perk, Joep, De Backer, Guy, Gohlke, Helmut, Graham, Ian, Reiner, Zeljko, Verschuren, Monique, Albus, Christian, Benlian, Pascale, Boysen, Gudrun, Cifkova, Renata, Deaton, Christi, Ebrahim, Shah, Fisher, Miles, Germano, Giuseppe, Hobbs, Richard, Hoes, Arno W., Karadeniz, Sehnaz, Mezzani, Alessandro, Prescott, Eva, Rydén, Lars E., Scherer, Martin, Syvänne, Mikko, op Reimer, Wilma Scholte, Vrints, Christiaan, Wood, David, Zamorano, José Luis, Zannad, Faiez, Cooney, Marie Therese, Bax, Jeroen J., Baumgartner, Helmut, Ceconi, Claudio, Dean, Veronica, Fagard, Robert, Funck-Brentano, Christian, Hasdai, David, Kirchhof, Paulus, Knuuti, Juhani, Kolh, Philippe, McDonagh, Theresa, Moulin, Cyril, Popescu, Bogdan A., Sechtem, Udo, Sirnes, Per Anton, Tendera, Michal, Torbicki, Adam, Vahanian, Alec, Windecker, Stephan, Aboyans, Victor, Ezquerra, Eduardo Alegria, Baigent, Colin, Brotons, Carlos, Burell, Gunilla, Ceriello, Antonio, De Sutter, Johan, Deckers, Jaap, Del Prato, Stefano, Diener, Hans-Christoph, Fitzsimons, Donna, Fras, Zlatko, Hambrecht, Rainer, Jankowski, Piotr, Keil, Ulrich, Kirby, Mike, Larsen, Mogens Lytken, Mancia, Giuseppe, Manolis, Athanasios J., McMurray, John J. V., Pajak, Andrzej, Parkhomenko, Alexander, Rallidis, Loukianos, Rigo, Fausto, Rocha, Evangelista, Ruilope, Luis Miguel, van der Velde, Enno, Vanuzzo, Diego, Viigimaa, Margus, Volpe, Massimo, Wiklund, Olov, and Wolpert, Christian

Published
2012

49. Linee guida europee sulla prevenzione delle malattie cardiovascolari nella pratica clinica (versione 2012).:Quinta Task Force congiunta della Società Europea di Cardiologia e di altre Società sulla Prevenzione delle Malattie Cardiovascolari nella Pratica Clinica (costituita da rappresentanti di nove società e da esperti invitati)

Author

Perk, Joep, De Backer, Guy, Gohlke, Helmut, Graham, Ian, Reiner, Zeljko, Verschuren, W M Monique, Albus, Christian, Benlian, Pascale, Boysen, Gudrun, Cifkova, Renata, Deaton, Christi, Ebrahim, Shah, Fisher, Miles, Germanò, Giuseppe, Hobbs, Richard, Hoes, Arno, Karadeniz, Sehnaz, Mezzani, Alessandro, Prescott, Eva, Ryden, Lars, Scherer, Martin, Syvanne, Mikko, Scholte Op Reimer, Wilma J M, Vrints, Christiaan, Wood, David, Zamorano, Jose Luis, Zannad, Faiez, Perk, Joep, De Backer, Guy, Gohlke, Helmut, Graham, Ian, Reiner, Zeljko, Verschuren, W M Monique, Albus, Christian, Benlian, Pascale, Boysen, Gudrun, Cifkova, Renata, Deaton, Christi, Ebrahim, Shah, Fisher, Miles, Germanò, Giuseppe, Hobbs, Richard, Hoes, Arno, Karadeniz, Sehnaz, Mezzani, Alessandro, Prescott, Eva, Ryden, Lars, Scherer, Martin, Syvanne, Mikko, Scholte Op Reimer, Wilma J M, Vrints, Christiaan, Wood, David, Zamorano, Jose Luis, and Zannad, Faiez

Published
2013

50. Linee guida europee sulla prevenzione delle malattie cardiovascolari nella pratica clinica (versione 2012). Quinta Task Force congiunta della Società Europea di Cardiologia e di altre Società sulla Prevenzione delle Malattie Cardiovascolari nella Pratica Clinica (costituita da rappresentanti di nove società e da esperti invitati)

Author

Perk, Joep, De Backer, Guy, Gohlke, Helmut, Graham, Ian, Reiner, Zeljko, Verschuren, W M Monique, Albus, Christian, Benlian, Pascale, Boysen, Gudrun, Cifkova, Renata, Deaton, Christi, Ebrahim, Shah, Fisher, Miles, Germanò, Giuseppe, Hobbs, Richard, Hoes, Arno, Karadeniz, Sehnaz, Mezzani, Alessandro, Prescott, Eva, Ryden, Lars, Scherer, Martin, Syvanne, Mikko, Scholte Op Reimer, Wilma J M, Vrints, Christiaan, Wood, David, Zamorano, Jose Luis, Zannad, Faiez, Perk, Joep, De Backer, Guy, Gohlke, Helmut, Graham, Ian, Reiner, Zeljko, Verschuren, W M Monique, Albus, Christian, Benlian, Pascale, Boysen, Gudrun, Cifkova, Renata, Deaton, Christi, Ebrahim, Shah, Fisher, Miles, Germanò, Giuseppe, Hobbs, Richard, Hoes, Arno, Karadeniz, Sehnaz, Mezzani, Alessandro, Prescott, Eva, Ryden, Lars, Scherer, Martin, Syvanne, Mikko, Scholte Op Reimer, Wilma J M, Vrints, Christiaan, Wood, David, Zamorano, Jose Luis, and Zannad, Faiez

Published
2013

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