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Introduction. Modern social challenges make it necessary to adapt the individual to rapidly changing conditions. The concept of generalized readiness of the individual is proposed as a socio-psychological construct that contributes to the effectiveness of such adaptation. Theoretical analysis. The article discusses domestic and foreign works describing the phenomenon of readiness, as well as constructs similar in content: vitality, resilience, tolerance to uncertainty. A comparative analysis of these concepts is carried out. The concept of generalized readiness is proposed as an attitude that presupposes a predisposition to certain social behavior and includes cognitive, motivational, emotional-volitional and behavioral components. The necessity of introducing the construct of generalized readiness for a wide range of social situations is substantiated, which represents a personal resource that helps to cope with situations of social challenge, uncertainty and maintain self-efficacy in changing conditions. The main content characteristics of a person’s generalized readiness are described. Conclusion. The analysis made it possible to formulate a definition of generalized readiness as a system of formed attitudes focused on effective life activity in conditions of uncertainty, manifested in a situation of interaction with Others, taking into account existing experience, self-esteem, ideas about one’s own competence and self-efficacy.

Epithelial to mesenchymal transition (EMT) is a cellular process that converts epithelial cells to mesenchymal cells with migratory potential in developmental and pathological processes. Although originally considered a binary event, EMT in cancer progression involves intermediate states between a fully epithelial and a fully mesenchymal phenotype, which are characterized by distinct combinations of epithelial and mesenchymal markers. This phenomenon has been termed epithelial to mesenchymal plasticity (EMP), however, the intermediate states remain poorly described and it’s unclear whether they exist during developmental EMT. Neural crest cells (NCC) are an embryonic progenitor cell population that gives rise to numerous cell types and tissues in vertebrates, and their formation and delamination is a classic example of developmental EMT. However, whether intermediate states also exist during NCC EMT and delamination remains unknown. Through single-cell RNA sequencing of mouse embryos, we identified intermediate NCC states based on their transcriptional signature and then spatially defined their locations in situ in the dorsolateral neuroepithelium. Our results illustrate the importance of cell cycle regulation and functional role for the intermediate stage marker Dlc1 in facilitating mammalian cranial NCC delamination and may provide new insights into mechanisms regulating pathological EMP.

Ecosystem management and governance of cross-scale dependent systems require integrating knowledge about ecological connectivity in its multiple forms and scales. Although scientists, managers, and policymakers are increasingly recognizing the importance of connectivity, governmental organizations may not be currently equipped to manage ecosystems with strong cross-boundary dependencies. Managing the different aspects of connectivity requires building social connectivity to increase the flow of information, as well as the capacity to coordinate planning, funding, and actions among both formal and informal governance bodies. We use estuaries in particular the San Francisco Estuary, in California, in the United States, as examples of cross-scale dependent systems affected by many intertwined aspects of connectivity. We describe the different types of estuarine connectivity observed in both natural and human-affected states and discuss the human dimensions of restoring beneficial physical and ecological processes. Finally, we provide recommendations for policy, practice, and research on how to restore functional connectivity to estuaries.

Landscape connectivity improves species’ capacity to adapt to climate change. These models are increasingly needed and available for climate-change conservation planning. However, their relative strengths and weaknesses are unclear. We asked how well do the spatial outputs from four connectivity models intended to support climate change conservation agree? To understand the implications of selecting one or several approaches, we compared various combinations of four connectivity models for ecoregions in California, U.S.A. Two models are based on landscape structure, Land Facet Corridors and Omniscape, while two other models, Meta-Corridor Approach and Network Flow Analysis (NFA), use focal species’ range dynamics to determine connectivity. We also describe how each approach integrates climate-adaptive connectivity concepts. Variation in modeling methods, objectives, inputs, and landscape representations strongly affects the modeled connectivity patterns. For the region where all four models were run, almost three quarters of the landscape was selected by one or more models, but three or more agree for only 9.5% of the area, all of which is riparian. This emphasizes the importance of riparian areas for climate adaptation. We found NFA prioritized connections close to protected areas, while Meta-Corridor avoided higher cost agricultural and developed areas. The structural models agreed in areas with low human impact but Omniscape avoided areas of low topographic diversity and Land Facet Corridors avoided connections in areas with no protected areas. Connectivity models should be selected based on the conservation objectives, such as spatial scale to be implemented, and a combination of models may be best.

The copepod Boeckella poppei (Mrazek, 1901) (Calanoida: Centropagidae) is one of the Maritime Antarctic’s most common freshwater zooplankton species. It was first discovered in 1961–1962 on Signy Island (South Orkney Islands). Nowadays, it is found on many other islands in the region. The copepod is also found on Western Subantarctic islands, in the eastern part of the continent, and South America. However, in the Wilhelm Archipelago, there have been only a few disjointed findings of the species so far: it has been noted as numerous both north and south of the Ukrainian Antarctic Akademik Vernadsky station, yet for the archipelago, there are only two brief records which do not describe its distribution in this region. Our data are based on 114 specimens collected in 2005–2023 during Ukrainian Antarctic Expeditions. Boeckella poppei was found in 51 samples from 23 lakes on eight islands: Uruguay, Irizar, Berthelot, Galindez, Roca, and Eight (Wilhelm Archipelago), Nelson, King George (South Shetland Islands). Live specimens were recorded during the ice-free period and significantly after the surface was frozen. In many samples, adults and copepodid stages were found, while nauplii were not found.

Natural resource managers need information about the risks associated with climate change to provide guidance on where to implement various management practices on natural lands. The spatial variation of projected impacts within a vegetation type can be used to target climate-adaptive management actions because different locations will be exposed to different levels of climatic stress. Vegetation refugia are areas that retain non-stressful climate conditions under future climates. Consensus vegetation refugia – areas retaining suitable climates under both wetter and drier future projections – represent only 14.6% of California's natural vegetation. One state and one federal government agency have incorporated vegetation refugia maps into conservation planning for 522 vertebrate species and for post-wildfire reforestation. Monitoring how vegetation responds to management actions at sites within vegetation refugia can improve the conservation of plants subjected to a changing climate.

A diffuse leptomeningeal glioneuronal tumours (DLGNT) are very rare tumours of the central nervous system, typically characterized by enhancement of subarachnoid space with cystic lesions, diffuse leptomeningeal infiltration, and no primary mass. We report an atypical clinical presentation of DLGNT. A 48-year-old male was admitted to hospital with symptoms of ischaemic stroke. Magnetic resonance imaging of the head revealed contrast enhancement of the meninges and other parts of the brain. A stereotactic frame biopsy was performed on the patient, which revealed the DLGNT. Diffuse leptomeningeal glioneuronal tumours are mostly seen in individuals less than 18 years old and are characterized by slow growth and low-grade histological appearance. Diffuse leptomeningeal glioneuronal tumours can be aggressive in adults.

Experiments were conducted to study the formation of copper minerals on carbonate material (marble) from lactate solutions. Main kinetic parameters were estimated from the curves of copper ions deposition. The reaction rate constant is $4.19 \times 10^{-6}~\text{s}^{-1}$ and the effective diffusion coefficient is $1.39 \times 10^{-12}~\text{m}^2/\text{s}$ at room temperature (25 °C). IR spectra of sediments show good agreement with natural samples of malachite and azurite (Spassk deposit, Central Kazakhstan). The results show the possibility of using organic complexing agents for intensifying the processes of secondary mineral formation of copper carbonate minerals (malachite and azurite) to prevent the dissipation of heavy metal ions in soluble forms from poor deposits and dumps during their remediation.

This short overview recalls the basic principles and technical aspects of skin and skeletal muscle biopsies in humans with paying special attention to the stages of these procedures essential for further correct morphological diagnosis. Some of these principles may also be useful in animal experimental studies. The authors emphasize the important role of proper thickness of the skin fragment, proper orientation of muscle fibres and a scalpel during skin biopsy, and proper concentration of fixatives. They recommend avoiding anaesthesia of the skeletal muscle itself and using forceps carefully so as not to crush the epidermis.

Introduction. Global transformations require an individual to be ready for change, the ability to make decisions in a situation of uncertainty. Theoretical analysis. A comparative analysis allows us to conclude that, depending on the context, readiness is understood differently. Psychological readiness is associated with the presence of knowledge, skills, and is considered as a certain level of activity of the individual, a special emotional-volitional state, the ability to mobilize before the start of activity. There is some overlap between the meanings of the concepts “readiness”, “competence” and “self-efficacy”. Empirical analysis. The study revealed that the concepts of “readiness” and “competence” contains such components as “confidence” and “preparedness”, and readiness and self-efficacy have common components “confidence”, “preparedness”, “goal”. Conclusion. The study made it possible to expand the concept of readiness as a special state, determined by decisiveness, determination, confidence, firmness, concentration and calmness, including strong-willed qualities and the ability to mobilize internal resources to solve a problem or achieve a goal.

Globally, thousands of institutions house nearly three billion scientific collections offering unparallelled resources that contribute to both science and society. For herbaria alone - facilities housing dried plant collections - there are over 3,000 herbaria worldwide with an estimated 350 million specimens that have been collected over the past four centuries. Digitisation has greatly enhanced the use of herbarium data in scientific research, impacting diverse research areas, including biodiversity informatics, global climate change, analyses using next-generation sequencing technologies and many others. Despite the entrance of herbaria into a new era with enhanced scientific, educational and societal relevance, museum specimens remain underused. Natural history museums can enhance learning and engagement in science, particularly for school-age and undergraduate students. Here, we outline a novel approach of a natural history museum using touchscreen technology that formed part of an interactive kiosk in a temporary museum exhibit on biological specimens. We provide some preliminary analysis investigating the efficacy of the tool, based on the Zooniverse platform, in an exhibit environment to engage patrons in the collection of biological data. We conclude there is great potential in using crowd‐sourced science, coupled with online technology to unlock data and information from digital images of natural history specimens themselves. Sixty percent of the records generated by community scientists (citizen scientists) were of high enough quality to be utilised by researchers. All age groups produced valid, high quality data that could be used by researchers, including children (10 and under), teens and adults. Significantly, the paper outlines the implementation of experiential learning through an undergraduate mathematics course that focuses on projects with actual data to gain a deep, practical knowledge of the subject, including observations, the collection of data, analysis and problem solving. We here promote an intergenerational model including children, high school students, undergraduate students, early career scientists and senior scientists, combining experiential learning, museum patrons, researchers and data derived from natural history collections. Natural history museums with their dual remit of education and collections-based research can play a significant role in the field of community engagement and people-powered research. There also remains much to investigate on the use of interactive displays to help learners interpret and appreciate authentic research. We conclude with a brief insight into the next phase of our ongoing people-powered research activities developed and designed by high school students using the Zooniverse platform.

This study tests whether teachers' emotional labor in classroom settings is optimally conceptualized according to the type of emotional labor strategy involved (genuinely expressing, hiding, and faking emotions), the specific type of emotion being performed in class (e.g., enjoyment vs. pride vs. anxiety), or both strategy type and emotion type. Multitrait-multimethod analyses of 1,086 Canadian teachers' survey responses showed teachers' responses to emotional labor items to be most reliably differentiated according to both specific types of emotional labor strategies as well as the valence of the emotion being performed. Findings were largely consistent with common "display rules" encouraging expression of positive emotions and hiding of negative emotions by teachers in classroom settings. Results further showed teachers' emotional labor strategies for negative emotions to be particularly contingent on the specific discrete emotion involved, highlighting the complexity of expressing negative emotions as a behavior management strategy.