1. [Afferent and efferent connections of cortical transplants implanted into the damaged sensorimotor area of the cerebral cortex of mature rats].
- Author
-
Obukhova GP, Gogeliia KhK, Senatorov VV, and Fiulëp Z
- Subjects
- Animals, Cerebral Cortex cytology, Graft Survival physiology, Motor Cortex injuries, Motor Cortex pathology, Neural Pathways cytology, Neural Pathways pathology, Neural Pathways physiology, Neurons, Afferent physiology, Neurons, Efferent physiology, Rats, Somatosensory Cortex injuries, Somatosensory Cortex pathology, Brain Tissue Transplantation methods, Cerebral Cortex transplantation, Embryo Transfer methods, Motor Cortex surgery, Neurons, Afferent transplantation, Neurons, Efferent transplantation, Somatosensory Cortex surgery
- Abstract
Afferent and efferent connections of the transplant, implanted in the previously damaged sensorimotor area of the mature rat cerebral cortex have been studied by means of axonal transport of horseradish peroxidase. For 5 months after transplantation neural axons of the transplant are capable to reach the caudo-putamen and thalamic structures, while connections with the spinal cord are absent. The afferent connections of the transplant are minimal and belong only to the neighbouring areas of the cortex and the caudo-putamen of the recipient brain. Presence of efferent projections to the striate and thalamic structures demonstrates specificity of the projections formed; this can be a morphological base for restoration of the functions lost after the damage of the sensorimotor area of the cortex in mature animals.
- Published
- 1990