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3. Development of quality indicators for the continued and safe delivery of Opioid Agonist Treatment (OAT), throughout and beyond COVID-19, using a Delphi Consensus technique

Author

Cousins, Gráinne, primary, Durand, Louise, additional, Boland, Fiona, additional, Harnedy, Norma, additional, Delargy, Íde, additional, Scully, Mike, additional, Bourke, Margaret, additional, Ebbitt, William, additional, Otero Vázquez, María, additional, Mayock, Paula, additional, Corrigan, Nicola, additional, Killeen, Nicki, additional, Goff, Paul, additional, Pate, Muriel, additional, Byrne, Paula, additional, and Keenan, Eamon, additional

Published
2021
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26. Persistent arthralgia and its association with HIV infection in Rwanda

Author

Saraux, Alain, Taelman, Henri, Clerinx, Jan, Batungwanayo, Jean, Kagame, Abel, Kabagabo, Lambert, Bogaerts, Jos, Perre, Philippe van de, and Le Goff, Paul

Subjects
Rwanda -- Health aspects, Joint diseases -- Risk factors, HIV infection -- Diagnosis, Intractable pain -- Causes of, Health
Abstract

Persistent arthralgia appears strongly associated with HIV infection in Rwanda. Arthralgia is joint pain. Of 331 female patients admitted to a hospital in Rwanda, 63% were HIV positive. Almost 7% of the HIV-positive women had persistent arthralgia. Slightly less than 1% of the HIV-negative women had persistent arthralgia. The knees were the most commonly affected joints. Ankle and elbow joints were also affected. Joints were symmetrically affected in 91.7% of the patients. Eighty-three percent of the patients treated with indomethacin, a nonsteroidal anti-inflammatory drug, experienced symptom resolution. In areas with high HIV-infection rates, persistent arthralgia may indicate that a patient is HIV-positive.

Published
1994

27. LETTERS.

Author

Lugsden, Jim, Rowena, Ratcliffe, Del, Durrant, Michael, Bootherstone, Phil, Lock, Simon, Goff, Paul, Bellinger, Keith, Bob, Oily Boot, Tucker, Andrew, Enright, Jack, Knowles, Mike, Thomson, Stu, Urquhart, Stuart, W., Frank, MacLennan, Alan, Narramore, Paul, Townsend, Ged, Cross, Roy, and Soady, Ian

Published
2018

45. Lipides et immunité

Author

Youinou, Pierre, primary, Menez, Jean-François, additional, Le Goff, Paul, additional, and Boles, Jean-Michel, additional

Published
1993
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49. Performance of Hand Radiographs in Predicting the Diagnosis in Patients with Early Arthritis

Author

Devauchelle-Pensec, Valerie, Berthelot, Jean, Jousse, Sandrine, Samjee, Isabelle, Josseaume, Thierry, Colin, Danielle, Chalés, Gerard, Thorel, Jean, Hoang, Sylvie, Martin, Antoine, Youinou, Pierre, Goff, Paul, and Saraux, Alain

Abstract

OBJECTIVE: To evaluate the ability of baseline hand radiographs to predict the diagnosis 2 years later in a cohort of patients with early arthritis. METHODS: A total of 258 patients with arthritis onset within the previous year were evaluated. At baseline, all patients underwent a standardized evaluation including laboratory tests and radiographs. Hand radiographs were read by a blinded observer who used a standardized procedure for detecting features of crystal deposition diseases and rheumatoid arthritis (RA). After 30 ± 11.3 months, the final diagnosis was established by a panel of rheumatologists. All radiographs were evaluated. RESULTS: Significant associations were found between radiographic features and a clinical diagnosis of RA, calcium pyrophosphate dihydrate (CPPD) arthritis, and hydroxyapatite arthritis. No radiographic abnormalities suggesting psoriatic arthritis or gout were seen. The sensitivities of hand radiographs for diagnosing CPPD or hydroxyapatite arthritis ranged from 80% to 100%. Baseline hand radiographs suggested the final diagnosis in 31/258 patients, including 21 (22.5%) of the 93 patients with RA, 10 of the 11 (91%) patients with CPPD or hydroxyapatite deposition disease, and none of the patients with other disorders. Sensitivity was 29%, specificity 86.5%, positive predictive value 61%, and negative predictive value 63%. CONCLUSION: In our cohort of patients with recent arthritis, the overall performance of hand radiographs in predicting a diagnosis 2 years later was modest. However, they had an excellent diagnostic value for calcium deposition diseases.

Published
2006

50. Ability of Foot Radiographs to Predict Rheumatoid Arthritis in Patients with Early Arthritis

Author

Pensec, Valérie, Saraux, Alain, Berthelot, Jean, Alapetite, Sabine, Jousse, Sandrine, Chales, Gérard, Thorel, Jean, Hoang, Sylvie, Nouy-Trolle, Isabelle, Martin, Antoine, Chiocchia, Gilles, Youinou, Pierre, and Le Goff, Paul

Abstract

OBJECTIVE: In a cohort of patients with early arthritis, to evaluate how well foot radiographs at study inclusion predicted a diagnosis of rheumatoid arthritis (RA) 2 years later. METHODS: A cohort of patients with arthritis of less than one year duration was evaluated in a multicenter study and followed for 30 ± 11 months. An observer blinded to patient data read all 149 hand and foot radiographs done at study inclusion, using item 7 of the 1987 American College of Rheumatology (ACR) criteria for RA and Sharp's method to score erosions and joint space narrowing. RESULTS: The kappa coefficient for the 1987 ACR item 7 was 0.52 for bony decalcification and 0.87 for erosions. Intra and interobserver correlation coefficients for Sharp's scores ranged from 0.90 to 0.98. Erosions at the feet were significantly associated with RA. The item 7 erosion component at the feet was more specific than the full item 7 (97.5% vs 94%; p = 0.01). Sharp's erosion score at the feet was not better than the erosion component of item 7 (sensitivity 18%; specificity 97.5%). Combined use of radiographs of the hands and feet improved the diagnostic performance of the item 7 erosion component; (sensitivity and specificity of item 7 erosions at the hands combined with the feet were 32.5% and 94.5%, respectively). CONCLUSION: The "erosion" criterion at the feet had the best diagnostic performance and was significantly associated with a diagnosis of RA. Combining hand and foot radiographs improved diagnostic performance.

Published
2004

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