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379 results on '"Godleski, John J."'

11. Data from Differentiation of Lung Adenocarcinoma, Pleural Mesothelioma, and Nonmalignant Pulmonary Tissues Using DNA Methylation Profiles

Author

Christensen, Brock C., primary, Marsit, Carmen J., primary, Houseman, E. Andres, primary, Godleski, John J., primary, Longacker, Jennifer L., primary, Zheng, Shichun, primary, Yeh, Ru-Fang, primary, Wrensch, Margaret R., primary, Wiemels, Joseph L., primary, Karagas, Margaret R., primary, Bueno, Raphael, primary, Sugarbaker, David J., primary, Nelson, Heather H., primary, Wiencke, John K., primary, and Kelsey, Karl T., primary

Published
2023
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12. Data from Epigenetic Profiles Distinguish Pleural Mesothelioma from Normal Pleura and Predict Lung Asbestos Burden and Clinical Outcome

Author

Christensen, Brock C., primary, Houseman, E.A., primary, Godleski, John J., primary, Marsit, Carmen J., primary, Longacker, Jennifer L., primary, Roelofs, Cora R., primary, Karagas, Margaret R., primary, Wrensch, Margaret R., primary, Yeh, Ru-Fang, primary, Nelson, Heather H., primary, Wiemels, Joe L., primary, Zheng, Shichun, primary, Wiencke, John K., primary, Bueno, Raphael, primary, Sugarbaker, David J., primary, and Kelsey, Karl T., primary

Published
2023
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14. Supplementary Table 1 from Epigenetic Profiles Distinguish Pleural Mesothelioma from Normal Pleura and Predict Lung Asbestos Burden and Clinical Outcome

Author

Christensen, Brock C., primary, Houseman, E.A., primary, Godleski, John J., primary, Marsit, Carmen J., primary, Longacker, Jennifer L., primary, Roelofs, Cora R., primary, Karagas, Margaret R., primary, Wrensch, Margaret R., primary, Yeh, Ru-Fang, primary, Nelson, Heather H., primary, Wiemels, Joe L., primary, Zheng, Shichun, primary, Wiencke, John K., primary, Bueno, Raphael, primary, Sugarbaker, David J., primary, and Kelsey, Karl T., primary

Published
2023
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16. Supplementary Figure 2 from Epigenetic Profiles Distinguish Pleural Mesothelioma from Normal Pleura and Predict Lung Asbestos Burden and Clinical Outcome

Author

Christensen, Brock C., primary, Houseman, E.A., primary, Godleski, John J., primary, Marsit, Carmen J., primary, Longacker, Jennifer L., primary, Roelofs, Cora R., primary, Karagas, Margaret R., primary, Wrensch, Margaret R., primary, Yeh, Ru-Fang, primary, Nelson, Heather H., primary, Wiemels, Joe L., primary, Zheng, Shichun, primary, Wiencke, John K., primary, Bueno, Raphael, primary, Sugarbaker, David J., primary, and Kelsey, Karl T., primary

Published
2023
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18. Supplementary Tables 1-6 from Differentiation of Lung Adenocarcinoma, Pleural Mesothelioma, and Nonmalignant Pulmonary Tissues Using DNA Methylation Profiles

Author

Christensen, Brock C., primary, Marsit, Carmen J., primary, Houseman, E. Andres, primary, Godleski, John J., primary, Longacker, Jennifer L., primary, Zheng, Shichun, primary, Yeh, Ru-Fang, primary, Wrensch, Margaret R., primary, Wiemels, Joseph L., primary, Karagas, Margaret R., primary, Bueno, Raphael, primary, Sugarbaker, David J., primary, Nelson, Heather H., primary, Wiencke, John K., primary, and Kelsey, Karl T., primary

Published
2023
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31. Chronic social stress and susceptibility to concentrated ambient fine particles in rats

Author

Clougherty, Jane E., Rossi, Christina A., Lawrence, Joy, Long, Mark S., Diaz, Edgar A., Lim, Robert H., McEwen, Bruce, Koutrakis, Petros, and Godleski, John J.

Subjects
Respiratory tract diseases -- Care and treatment -- Risk factors, Disease susceptibility -- Care and treatment -- Risk factors, Air pollution -- Health aspects, Stress (Psychology) -- Risk factors -- Care and treatment
Abstract

BACKGROUND: Epidemiologic evidence suggests that chronic stress may alter susceptibility to air pollution. However, persistent spatial confounding between these exposures may limit the utility of epidemiologic methods to disentangle these [...]

Published
2010
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33. Does the Harvard/U.S. Environmental Protection Agency Ambient Particle Concentrator change the toxic potential of particles?

Author

Savage, Sara T., Lawrence, Joy, Katz, Tracy, Stearns, Rebecca C., Coull, Brent A., and Godleski, John J.

Subjects
Toxicological chemistry -- Research -- Reports -- Health aspects -- Chemical properties -- Statistics, Air quality management -- Standards -- Statistics, Environmental services industry, Environmental issues, Science and technology
Abstract

ABSTRACT Inhalation exposure to urban air particles is known to increase morbidity in humans and animals, Our group utilizes the Harvard/U.S. Environmental Protection Agency Ambient Particle Concentrator (HAPC) to generate [...]

Published
2003

34. Consultants

Author

Aster, Jon Christopher, primary, Brodsky, Gilbert, additional, Chirieac, Lucian R., additional, Cibas, Edmund S., additional, Corson, Joseph M., additional, Crawford, James M., additional, Crum, Christopher P., additional, Cin, Paola Dal, additional, Dillon, Deborah A.R., additional, Dorfman, David M., additional, Fletcher, Christopher D.M., additional, Fletcher, Jonathan A., additional, Folkerth, Rebecca D., additional, French, Christopher A., additional, Godleski, John J., additional, Granter, Scott R., additional, Hirsch, Michelle S., additional, Hornick, Jason L., additional, Kobzik, Lester, additional, Krane, Jeffrey F., additional, Kuo, Frank C., additional, Kutok, Jeffery L., additional, Ligon, Keith L., additional, Loda, Massimo F., additional, Longtine, Janina A., additional, Milner, Danny A., additional, Mitchell, Richard N., additional, Nosé, Vânia, additional, Nucci, Marisa R., additional, Odze, Robert D., additional, Padera, Robert F., additional, Pinkus, Geraldine S., additional, Quade, Bradley J., additional, Rennke, Helmut G., additional, Richardson, Andrea L., additional, Roberts, Drucilla J., additional, Schoen, Frederick J., additional, Vargas, Sara O., additional, Welch, William R., additional, Wieczorek, Tad J., additional, and Winters, Gayle L., additional

Published
2010
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35. Concentrated ambient air particles induce vasoconstriction of small pulmonary arteries in rats

Author

Batalha, Joao R.F., Saldiva, Paulo H.N., Clarke, Robert W., Coull, Brent A., Stearns, Rebecca C., Lawrence, Joy, Murthy, G.G. Krishna, Koutrakis, Petros, and Godleski, John J.

Abstract

The objective of this study was to determine whether short-term exposures to concentrated ambient particles (CAPs) alter the morphology of small pulmonary arteries in normal rats and rats with chronic [...]

Published
2002

39. List of Consultants

Author

Aster, Jon Christopher, primary, Brenn, Thomas, additional, Brodsky, Gilbert, additional, Cibas, Edmund S., additional, Corson, Joseph M., additional, Crawford, James M., additional, Crum, Christopher P., additional, Dal Cin, Paola, additional, De Girolami, Umberto, additional, Dorfman, David M., additional, Fletcher, Christopher D.M., additional, Fletcher, Jonathan A., additional, French, Christopher A., additional, Folkerth, Rebecca D., additional, Genest, David R., additional, Glickman, Jonathan N., additional, Godleski, John J., additional, Granter, Scott R., additional, Hirsch, Michelle S., additional, Hornick, Jason L., additional, Kobzik, Lester, additional, Krane, Jeffrey F., additional, Kuo, Frank C., additional, Kutok, Jeffery L., additional, Ligon, Keith L., additional, Loda, Massimo F., additional, Longtine, Janina A., additional, Mitchell, Richard N., additional, Nosé, Vânia, additional, Nucci, Marisa R., additional, Odze, Robert D., additional, Pinkus, Geraldine S., additional, Quade, Bradley J., additional, Redston, Mark S., additional, Rennke, Helmut G., additional, Richardson, Andrea L., additional, Roberts, Drucilla J., additional, Rubin, Mark A., additional, Schoen, Frederick J., additional, Vargas, Sara O., additional, Welch, William R., additional, Wieczorek, Tad J., additional, and Winters, Gayle L., additional

Published
2006
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43. Correlative polarizing light and scanning electron microscopy for the assessment of talc in pelvic region lymph nodes

Author

McDonald, Sandra A., Yuwei Fan, Welch, William R., Cramer, Daniel W., Stearns, Rebecca C., Sheedy, Liam, Katler, Marshall, and Godleski, John J.

Abstract

Perineal talc use is associated with ovarian carcinoma in many case-control studies. Such talc may migrate to pelvic organs and regional lymph nodes, with both clinical and legal significance. Our goal was to differentiate talc in pelvic lymph nodes due to exposure, versus contamination with talc in the laboratory. We studied 22 lymph nodes from ovarian tumor patients, some of which had documented talc exposure, to quantify talc using digestion of tissue taken from paraffin blocks and scanning electron microscopy/energy dispersive X-ray analysis (SEM/EDX). Talc particles correlated significantly with surface contamination assessments using polarized light microscopy. After adjusting for surface contamination, talc burdens in nodes correlated strongly with perineal talc use. In a separate group of lymph nodes, birefringent particles within the same plane of focus as the tissues in histological sections were highly correlated with talc particles within the tissue by in situ SEM/EDX (r = 0.80; p < 0.0001). We conclude that since talc can be a surface contaminant from tissue collection/preparation, digestion measurements may be influenced by contamination. Instead, because they preserve anatomic landmarks and permit identification of particles in cells and tissues, polarized light microscopy and in situ SEM/EDX are recommended to assess talc in lymph nodes.

Published
2019
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