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155 results on '"Gobert, M."'

3. (293) Altered Pigr/Iga Mucosal Immunity in Bronchiolitis Obliterans Syndrome

Author

Carlier, F.M., primary, Pretolani, M., additional, Detry, B., additional, Planté-Bordeneuve, T., additional, Longchampt, E., additional, Falque, L., additional, Reynaud-Gobert, M., additional, Hirschi, S., additional, Demant, X., additional, Mornex, J., additional, Tissot, A., additional, Pavec, J. Le, additional, Bunel-Gourdy, V., additional, Foureau, A., additional, Vallée, A., additional, Pilette, C., additional, and Brugière, O., additional

Published
2023
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4. Atteintes interstitielles pulmonaires au cours du lupus érythémateux systémique. Étude rétrospective multicentrique de 89 cas

Author

Mageau, A., primary, Deneuville, L., additional, Debray, M.P., additional, Sacre, K., additional, Cottin, V., additional, Costedoat-Chalumeau, N., additional, Hachulla, E., additional, Uzunhan, Y., additional, Le Tallec, E., additional, Cadranel, J., additional, Marchand-Adam, S., additional, Montani, D., additional, Reynaud-Gobert, M., additional, Prevot, G., additional, Beltramo, G., additional, Crestani, B., additional, and Borie, R., additional

Published
2022
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18. [Pharmacological treatment of hypercholesterolaemia in primary prevention. The use of the different sources of information]

Author

Van Den Bruel, A, Gobert, M, Vermeire, E, Buntinx, F, and Aertgeerts, B

Abstract

In the first two articles of this series devoted to Evidence-Based Medicine, we have shown how to translate a clinical problem in a well formulated question and how to derive search terms from the PICO. In this article, we describe in more detail the different sources of information and how to use them. The strategy will be illustrated by answering the question whether it should be recommended to treat hypercholesterolaemia in a young woman without cardiovascular risk factors. In a following article, we will show how to adapt a search strategy to a specific question or PICO.

Published
2016

22. Accompagnement Equipes Nutritionnelles

Author

Bocquaert, I., Dardenne, O., Lopez Hartmann, M., Jacquemin, Patricia, Vanderwee, K., Geurden, B., Gobert, M., Defloor, T., Bocquaert, I., Dardenne, O., Lopez Hartmann, M., Jacquemin, Patricia, Vanderwee, K., Geurden, B., Gobert, M., and Defloor, T.

Abstract

Bruxelles, info:eu-repo/semantics/published

Published
2009

23. Financement du programme de soins pour le patient gériatrique dans l'hôpital classique. : Définition et évaluation du patient gériatrique, fonction de liaison et évaluation d'un instrument pour un financement approprié

Author

Gobert, M, Pepersack, Thierry, Falez, Freddy, Baeyens, Jean-Pierre, Kohn, Laurence, Swartenbroekx, Nathalie, Léonard, Christian, Closon, Marie-Christine, Gobert, M, Pepersack, Thierry, Falez, Freddy, Baeyens, Jean-Pierre, Kohn, Laurence, Swartenbroekx, Nathalie, Léonard, Christian, and Closon, Marie-Christine

Abstract

ix, 239 p., ill.

Published
2008

25. Financiering van het zorgprogramma voor de geriatrische patiënt in algemene ziekenhuizen. : Definitie en evaluatie van een geriatrische patiënt, definitie van de interne liaisongeriatrie en evaluatie van de middeln voor een goede financiering

Author

Gobert, M, Pepersack, Thierry, Falez, Freddy, Baeyens, Jean-Pierre, Kohn, Laurence, Swartenbroekx, Nathalie, Léonard, Christian, Closon, Marie-Christine, Gobert, M, Pepersack, Thierry, Falez, Freddy, Baeyens, Jean-Pierre, Kohn, Laurence, Swartenbroekx, Nathalie, Léonard, Christian, and Closon, Marie-Christine

Abstract

ix, 239 p., ill.

Published
2008

27. Macroadénome hypophysaire chez le sujet âgé : une présentation souvent atypique. A propos de deux observations

Author

UCL - (SLuc) Service d'endocrinologie et de nutrition, UCL - MD/MINT - Département de médecine interne, Ho, T.T., Frankart, J-L., Gobert, M., Maiter, Dominique, UCL - (SLuc) Service d'endocrinologie et de nutrition, UCL - MD/MINT - Département de médecine interne, Ho, T.T., Frankart, J-L., Gobert, M., and Maiter, Dominique

Abstract

Cet article rapporte deux observations cliniques récentes chez des patients âgés, hospitalisés dans un contexte d’altération de l’état général et neurologique. Le diagnostic de macroadénome hypophysaire non fonctionnel a pu être posé sur base de dosages hormonaux orientés et d’une IRM centrée sur la région sellaire. Nous avons voulu mettre en évidence la présentation assez atypique de cette pathologie chez la personne âgée, ainsi que l’amélioration clinique rapide sous traitement hormonal substitutif.

Published
2007

29. L'utilisation des médicaments dans les maisons de repos et les maisons de repos et de soins belges

Author

UCL - MD/ESP - Ecole de santé publique, UCL - (SLuc) Service de gériatrie, UCL - (MGD) Service de médecine gériatrique, Chevalier, Pierre, Gobert, M., Spinewine, A., Swine, Christian, UCL - MD/ESP - Ecole de santé publique, UCL - (SLuc) Service de gériatrie, UCL - (MGD) Service de médecine gériatrique, Chevalier, Pierre, Gobert, M., Spinewine, A., and Swine, Christian

Published
2006

30. Geneesmiddelen gebruik in de Belgische rusthuizen en rust- en verzorgingstehuizen

Author

Van de Voorde, Carine, Christiaens, Th, Bauwens, M, De Falleur, M, Gobert, M, Somers, A., Mehuys, E., De Floor, T, Chevalier, P, Petrovic, M, Smet, M., Soenen, K., Verrue, C., Elseviers, MM, Devriese, Stephan, Ramaekers, Dirk, Spinewine, A., Vander Stichele, Robert H., Van de Voorde, Carine, Christiaens, Th, Bauwens, M, De Falleur, M, Gobert, M, Somers, A., Mehuys, E., De Floor, T, Chevalier, P, Petrovic, M, Smet, M., Soenen, K., Verrue, C., Elseviers, MM, Devriese, Stephan, Ramaekers, Dirk, Spinewine, A., and Vander Stichele, Robert H.

Abstract

Viii, 196 p., ill.

Published
2006

31. L'utilisation des médicaments dans les maisons de repos et les maisons de repos et de soins belges

Author

Van de Voorde, Carine, Christiaens, Th, Bauwens, M, De Falleur, M, Gobert, M, Somers, A., Mehuys, E., De Floor, T, Chevalier, P, Petrovic, M, Smet, M., Soenen, K., Verrue, C., Elseviers, MM, Devriese, Stephan, Ramaekers, Dirk, Spinewine, A., Vander Stichele, Robert H., Van de Voorde, Carine, Christiaens, Th, Bauwens, M, De Falleur, M, Gobert, M, Somers, A., Mehuys, E., De Floor, T, Chevalier, P, Petrovic, M, Smet, M., Soenen, K., Verrue, C., Elseviers, MM, Devriese, Stephan, Ramaekers, Dirk, Spinewine, A., and Vander Stichele, Robert H.

Abstract

ix, 196 p., ill.

Published
2006

32. Medication use in rest and nursing homes in Belgium

Author

Van de Voorde, Carine, Christiaens, Th, Bauwens, M, De Falleur, M, Gobert, M, Somers, A., Mehuys, E., De Floor, T, Chevalier, P, Petrovic, M, Smet, M., Soenen, K., Verrue, C., Elseviers, MM, Devriese, Stephan, Ramaekers, Dirk, Spinewine, A., Vander Stichele, Robert H., Van de Voorde, Carine, Christiaens, Th, Bauwens, M, De Falleur, M, Gobert, M, Somers, A., Mehuys, E., De Floor, T, Chevalier, P, Petrovic, M, Smet, M., Soenen, K., Verrue, C., Elseviers, MM, Devriese, Stephan, Ramaekers, Dirk, Spinewine, A., and Vander Stichele, Robert H.

Abstract

vii, 12 p., ill.

Published
2006

41. Nonmetastatic tumor cells acquire metastatic properties following somatic hybridization with normal cells

Author

Baetselier, P., Roos, E., Brys, L., Remels, L., Gobert, M., Dekegel, D., Segal, S., and Feldman, M.

Abstract

Somatic cell hybridization between nonmetastatic tumor cells and normal cells of the lymphoreticular system results in hybrid cells manifesting metastatic properties of defined target organ specificity. Thus, fusion of the nonmetastatic BALB/c originated NSI plasmacytoma with C57BL B lymphocytes resulted in hybridomas, each of which were metastatic. Of 10 hybridomas, 7 generated metastases in the spleen and liver, whereas 3 generated liver metastases. The generation of liver metastases by hybridomas which homed to both spleen and liver, but not by those which homed to the liver only, was controlled by the spleen. The acquisition of metastatic properties via somatic cell fusion seems to represent a general principle, in which the normal partner determines the target organ specificity for the metastatic growth. Thus, fusion of SP2/O myeloma cells with syngeneic B lymphocytes also resulted in a hybrid cell metastasizing to the spleen and liver, yet a somatic hybrid between NSI and a macrophage or dendritic-like cell metastasized to the lung. Cell surface molecules encoded by the genome of the normal partner was demonstrated to control the target organ specificity: antibodies against MHC-encoded antigens of the normal B cell partner prevented the generation of metastases by hybridomas metastasizing to the spleen and liver, but not by those metastasizing to the liver only. This is in accordance with the function of MHC molecules on lymphocytes in controlling their homing to lymphoid organs. Hybridomas of T cell lymphomas also manifested metastatic properties. Analysis of the cell surface Thy-1 antigens of a hybridoma (DCH10), produced via somatic fusion between BW5145 lymphoma and a putative macrophage cell indicated that cells of liver metastases (DCH10-Li) generated by the hybrid cells might have undergone further somatic cell fusion in vivo with host (T?) cells. These cells have acquired new metastatic properties, generating metastases in spleen, liver and kidneys. In fact, even the inoculation of the parental BW lymphoma cells resulted in a case of liver metastasis (BW-Li). Such BW-Li cells, upon reinoculation, also generated metastases in the spleen, liver and kidneys. Analysis of the Thyl phenotype indicated that BW-Li cells may also have undergone somatic cell fusion in vivo with host (T?) cells, resulting in the acquisition of metastatic properties. The pattern of cell-cell interactions (adhesion, infiltration) with liver cell monolayers of BW-Li cells and of DCH10-Li (T-cell lymphomas) was identical, and differed from cells of liver metastases of the myeloma-B cell hybridomas which might be based on responses to liver growth signals. Accordingly, the morphology of liver metastases generated by the two categories of hybridomas was different. It appears therefore, that (a) the acquisition of metastatic properties following somatic cell fusion with normal lymphoreticular cells is of a general significance; (b) somatic cell fusion provides an experimental system for the analysis of molecular properties determining the acquisition of metastatic capability; and (c) it may also represent a mechanism for tumor progression in vivo.

Published
1984
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44. Functiedifferentiatie in de verpleegkundige zorg : mogelijkheden en beperkingen

Author

Berckmans, Geoffroy, Alvarez Irusta, Lucia, Bouzegta, Nadia, Defloor, Tom, Peeters, Gert, Stordeur, Sabine, and Gobert, M

Subjects
WY 125 Institutional nursing. Team nursing, Job Description, R86, Allied Health Personnel, Clinical Competence, Nursing Staff, Hospital, Needs Assessment, 2006-22
Abstract

vi, 330 p. ill.

Published
2008

45. Différenciation de fonctions dans les soins infirmiers : possibilités et limites

Author

Berckmans, Geoffroy, Alvarez Irusta, Lucia, Bouzegta, Nadia, Defloor, Tom, Peeters, Gert, Stordeur, Sabine, and Gobert, M

Subjects
WY 125 Institutional nursing. Team nursing, Job Description, R86, Allied Health Personnel, Clinical Competence, Nursing Staff, Hospital, Needs Assessment, 2006-22
Abstract

vi, 330 p. ill.

Published
2008

46. Financement du programme de soins pour le patient gériatrique dans l'hôpital classique. : Définition et évaluation du patient gériatrique, fonction de liaison et évaluation d'un instrument pour un financement approprié

Author

Closon, Marie-Christine, Gobert, M, Pepersack, Thierry, Falez, Freddy, Baeyens, Jean-Pierre, Kohn, Laurence, Swartenbroekx, Nathalie, and Léonard, Christian

Subjects
R73, Frail Elderly, Financing, Organized, 2006-18, Geriatric Assessment, WT 27 Hospitals, dispensaries, clinics, old age homes, etc -- Collective
Abstract

ix, 239 p. ill.

Published
2008

47. Geneesmiddelen gebruik in de Belgische rusthuizen en rust- en verzorgingstehuizen

Author

Vander Stichele, Robert H., Van de Voorde, Carine, Christiaens, Th, Bauwens, M, De Falleur, M, Gobert, M, Somers, A., Mehuys, E., De Floor, T, Chevalier, P, Petrovic, M, Smet, M., Soenen, K., Verrue, C., Elseviers, MM, Devriese, Stephan, Ramaekers, Dirk, and Spinewine, A.

Subjects
Quality Assurance, Health Care, Pharmaceutical Services, 2005-17, Homes for the Aged, R47, Health Care Costs, Health Services Research, Drug Utilization, WT 27 Hospitals, dispensaries, clinics, old age homes, etc -- Collective
Abstract

Viii, 196 p. ill.

Published
2006

48. L'utilisation des médicaments dans les maisons de repos et les maisons de repos et de soins belges

Author

Vander Stichele, Robert H., Van de Voorde, Carine, Christiaens, Th, Bauwens, M, De Falleur, M, Gobert, M, Somers, A., Mehuys, E., De Floor, T, Chevalier, P, Petrovic, M, Smet, M., Soenen, K., Verrue, C., Elseviers, MM, Devriese, Stephan, Ramaekers, Dirk, and Spinewine, A.

Subjects
Quality Assurance, Health Care, Pharmaceutical Services, 2005-17, Homes for the Aged, R47, Health Care Costs, Health Services Research, Drug Utilization, WT 27 Hospitals, dispensaries, clinics, old age homes, etc -- Collective
Abstract

ix, 196 p. ill.

Published
2006

49. Medication use in rest and nursing homes in Belgium

Author

Vander Stichele, Robert H., Van de Voorde, Carine, Christiaens, Th, Bauwens, M, De Falleur, M, Gobert, M, Somers, A., Mehuys, E., De Floor, T, Chevalier, P, Petrovic, M, Smet, M., Soenen, K., Verrue, C., Elseviers, MM, Devriese, Stephan, Ramaekers, Dirk, and Spinewine, A.

Subjects
Quality Assurance, Health Care, Pharmaceutical Services, 2005-17, Homes for the Aged, R47, Health Care Costs, Health Services Research, Drug Utilization, WT 27 Hospitals, dispensaries, clinics, old age homes, etc -- Collective
Abstract

vii, 12 p. ill.

Published
2006

50. Survival and Prognostic Factors After Adrenalectomy for Secondary Malignancy: A Combined Analysis of a French University Center Registry (Eurocrine) of 307 Patients and a French Nationwide Study of 2515 Patients.

Author

Rémond A, Marciniak C, Lenne X, Chouraki V, Gobert M, Baud G, Maillard L, Bouriez D, Liekens E, Donatini G, Nominé-Criqui C, Ravenet A, Santucci N, Kuczma P, Bouviez N, Tresallet C, Mirallié E, Deguelte S, Brunaud L, Guerin C, Gronnier C, Lifante JC, Bruandet A, Theis D, Cortot A, Scherpereel A, Hamroun A, Pattou F, and Caiazzo R

Subjects
Humans, France epidemiology, Male, Female, Middle Aged, Aged, Prognosis, Survival Rate, Adult, Neoplasms, Second Primary, Adrenalectomy, Adrenal Gland Neoplasms surgery, Adrenal Gland Neoplasms secondary, Adrenal Gland Neoplasms mortality, Registries
Abstract

Objective: To provide a nationwide description of postoperative outcomes and analysis of prognostic factors following adrenalectomy for metastases., Background: Adrenal glands are a common site of metastases in many malignancies. Diagnosis of adrenal metastases is on the rise, leading to an increasing number of patient candidates for surgery without consensual management., Methods: We conducted a population-based study between January 2012 and December 2022 using the French National Health Data System (SNDS) and the Eurocrine registry (NCT03410394). The first database exhaustively covers all procedures carried out in France, while the second provides more clinical information on procedures and tumor characteristics, based on the experience of 11 specialized centers., Results: From the SNDS, we extracted 2515 patients who underwent adrenalectomy for secondary malignancy and 307 from the Eurocrine database. The most common primary malignancies were lung cancer (n=1203, 47.8%) and renal cancer (n=555, 22.1%). One-year survival was 84.3% (n=2120). Thirty-day mortality and morbidity rates were, respectively, 1.3% (n=32) and 29.9% (n=753, including planned intensive care unit - stays). Radiotherapy within the year before adrenalectomy was significantly associated with higher 30-day major complication rates ( P =0.039). In the Eurocrine database, the proportion of laparoscopic procedures reached 85.3% without impairing resection completeness (R0: 92.9%). Factors associated with poor overall survival were the presence of extra-adrenal metastases (hazard ratio =0.64; P =0.031) and incomplete resection (≥R1; hazard ratio=0.41; P =0.015)., Conclusions: The number of patients who can receive local treatment for adrenal metastases is rising, and adrenalectomy is more often minimally invasive and has a low morbidity rate. Subsequent research should evaluate which patients would benefit from adrenal surgery., Competing Interests: The authors report no conflicts of interest., (Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.)

Published
2024
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