Search

Your search keyword '"Goadsby, PJ"' showing total 1,212 results
Start Over Author "Goadsby, PJ"
1,212 results on '"Goadsby, PJ"'

3. Postoperative hemicrania continua-like headache - a case series

Author

Goadsby, Peter, Gantenbein, AR, Sarikaya, H, Riederer, F, and Goadsby, PJ

Abstract

© 2015, Gantenbein et al.; licensee Springer.Background: Hemicrania continua (HC) is a rare chronic headache disorder, typically accompanied by cranial autonomic features and responding to therapeutic doses of indomethacin. The pathophysiology of hemicrani

Published
2015

4. Single-pulse transcranial magnetic stimulation (sTMS) for the acute treatment of migraine: evaluation of outcome data for the UK post market pilot program

Author

Goadsby, Peter, Bhola, R, Kinsella, E, Giffin, N, Lipscombe, S, Ahmed, F, Weatherall, M, and Goadsby, PJ

Abstract

© 2015, Bhola et al.Background: Single pulse transcranial magnetic stimulation (sTMS) is a novel treatment for acute migraine. Previous randomised controlled data demonstrated that sTMS is effective and well tolerated in the treatment of migraine with aura

Published
2015

5. Nociception-specific blink reflex: pharmacology in healthy volunteers

Author

Goadsby, Peter, Marin, JCA, Gantenbein, AR, Paemeleire, K, Kaube, H, and Goadsby, PJ

Abstract

© 2015, Marin et al.Background: The physiology and pharmacology of activation or perception of activation of pain-coding trigeminovascular afferents in humans is fundamental to understanding the biology of headache and developing new treatments. Methods: T

Published
2015

8. Migraine misdiagnosis as a sinusitis, a delay that can last for many years.

Author

Goadsby, Peter, Al-Hashel, JY, Ahmed, SF, Alroughani, R, and Goadsby, PJ

Abstract

Sinusitis is the most frequent misdiagnosis given to patients with migraine.Therefore we decided to estimate the frequency of misdiagnosis of sinusitis among migraine patients. The study included migraine patients with a past history of sinusitis. All incl

Published
2013

9. New onset migraine with aura after treatment initiation with ivabradine

Author

Goadsby, Peter, Sprenger, T, Supronsinchai, W, and Goadsby, PJ

Abstract

Background: Migraine with aura is a complex neurological disorder modeled in animals by cortical spreading depression. It is less usual to find complete animal models for the disease so any opportunity to test a human effect back at the bench is welcome. F

Published
2013

11. Headache-related health resource utilisation in chronic and episodic migraine across six countries

Author

Goadsby, Peter, Sanderson, JC, Devine, EB, Lipton, RB, Bloudek, LM, Varon, SF, Blumenfeld, AM, Goadsby, PJ, Buse, DC, and Sullivan, SD

Abstract

Objective: To describe headache-related health resource usage in chronic and episodic migraine across six countries. Methods: A web-based questionnaire eliciting data on several topics, including health resource usage, was administered to panellists with m

Published
2013

12. Cost of healthcare for patients with migraine in five European countries: Results from the International Burden of Migraine Study (IBMS)

Author

Goadsby, Peter, Bloudek, LM, Stokes, M, Buse, DC, Wilcox, TK, Lipton, RB, Goadsby, PJ, Varon, SF, Blumenfeld, AM, Katsarava, Z, and Pascual, J

Abstract

Migraine is a disabling neurological disease that affects 14.7 % of Europeans. Studies evaluating the economic impact of migraine are complex to conduct adequately and with time become outdated as healthcare systems evolve. This study sought to quantify an

Published
2012

16. 21st century headache: mapping new territory

Author

Goadsby, PJ, Lanteri-Minet, M, Michel, MC, Peres, M, Shibata, M, Straube, A, Wijeratne, T, Ebel-Bitoun, C, Constantin, L, Hitier, S, Goadsby, PJ, Lanteri-Minet, M, Michel, MC, Peres, M, Shibata, M, Straube, A, Wijeratne, T, Ebel-Bitoun, C, Constantin, L, and Hitier, S

Abstract

BACKGROUND: With headache experienced by up to 75% of adults worldwide in the last year, primary headache disorders constitute a major public health problem, yet they remain under-diagnosed and under-treated. Headache prevalence and burden is changing as society evolves, with headache now occurring earlier in life. Contributing factors, mostly associated with changing life style, such as stress, bad posture, physical inactivity, sleep disturbance, poor diet and excess use of digital technology may be associated with the phenomenon that could be labelled as '21st century headache'. This is especially notable in workplace and learning environments where headache impacts mental clarity and therefore cognitive performance. The headache-related impact on productivity and absenteeism negatively influences an individual's behaviour and quality of life, and is also associated with a high economic cost. Since the majority of sufferers opt to self-treat rather than seek medical advice, substantial knowledge on headache prevalence, causation and burden is unknown globally. Mapping the entire population of headache sufferers can close this knowledge gap, leading to better headache management. The broad use of digital technology to gather real world data on headache triggers, burden and management strategies, in self-treated population will allow these sufferers to access appropriate support and medication, and therefore improve quality of life. CONCLUSION: These data can yield important insights into a substantial global healthcare issue and form the basis for improved patient awareness, professional education, clinical study design and drug development.

Published
2021

48. Pituitary adenylate cyclase activating polypeptide and migraine

Author

Zagami, AS, Edvinsson, L, Goadsby, PJ, Zagami, AS, Edvinsson, L, and Goadsby, PJ

Abstract

Pituitary adenylate cyclase activating peptide (PACAP) is found in human trigeminocervical complex and can trigger migraine. PACAP levels were measured using a sensitive radioimmunoassay. Stimulation of the superior sagittal sinus (SSS) in cat elevated PACAP levels in cranial blood. Patients with moderate or severe migraine headache had elevated PACAP in the external jugular vein during headache (n = 15), that was reduced 1 h after treatment with sumatriptan 6 mg (n = 11), and further reduced interictally (n = 9). The data suggest PACAP, or its receptors, are a promising target for migraine therapeutics.

Published
2014

Catalog

Books, media, physical & digital resources
See catalog results