315 results on '"Glucides"'
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2. Recommandations nutritionnelles lors de diabète sucré chez le chien et le chat.
- Author
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Blanchard, Géraldine
- Abstract
Copyright of Nouveau Praticien Vétérinaire Canine & Féline is the property of EDP Sciences and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2023
- Full Text
- View/download PDF
3. Food cravings during the first week of concussion.
- Author
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Kazemi, Mohsen
- Subjects
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CROSS-sectional method , *DESIRE , *APOPTOSIS , *FISHER exact test , *BRAIN concussion , *DESCRIPTIVE statistics , *CARBOHYDRATES , *CHI-squared test , *GLUCOSE , *DATA analysis software , *SYMPTOMS - Abstract
The brain utilizes glucose as its main source of energy. Traumatic brain injuries may alter the brain's ability to shuttle glucose effectively; therefore, the symptoms experienced may be a signal of the dysregulation. The objective of this cross-sectional study was to investigate the presence of any specific food cravings during the first week post-concussion and if the consumption of such a food decreased the symptoms of concussion. The link to the survey was posted on 4 Canadian organization websites from November 2020 to February 2021. Any individual over 18 years old who had suffered one of more concussions in the past 12 months was included. 73 females and 24 males, the majority aged 18-40 years, completed the survey. Participants with combined carbohydrate and sweet cravings reported significantly more symptoms of increased emotions (p=0.04), irritability (p=0.03), sadness (p=0.04), nervousness (p=0.03), and sleep disturbances (p=0.05) than those without these cravings. Consumption of the craved food did not change the concussion symptoms. [ABSTRACT FROM AUTHOR]
- Published
- 2022
4. NMR and molecular recognition: The interaction of human galectin-4 with the histo blood group antigens and with pathogen-associated molecules
- Author
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Jiménez Barbero, Jesús, Ardá, Ana, Química Orgánica e Inorgánica, Kimika Organikoa eta Ez-Organikoa, Quintana García, Jon Imanol, Jiménez Barbero, Jesús, Ardá, Ana, Química Orgánica e Inorgánica, Kimika Organikoa eta Ez-Organikoa, and Quintana García, Jon Imanol
- Abstract
233 p., Glycans are essential molecules that are ubiquitously found in every living cell. The interaction betweengalect in 4, a human sugar binding protein, with the histo blood group antigens has been studied by NuclearMagnetic Resonance ( Isothermal Titration Calorimetry and Molecular Dynamics simulations. Theeffect of the chemical modification of these antigens on the interaction with galectin 4 has been addressed.These antigens are mimicked by various pathogens, thus, the interaction between galectin 4 and theantigenic fragment of these pathogens ( LPS) has also been studied using NMR. Them ain co receptor for LPS, the glycoprotein CD14 has also been analysed. The relevance of each of theglycans of CD14 in its stability and folding, as well as for the interaction with galectin 4 has beencharacterized. Finally, using a solid phase synthesize r, the synthesis of oligosaccharides has beenperformed.
- Published
- 2024
5. Lectin-Glycan Interactions: new NMR insights on the role of dynamics and presentation by using state-of-the-art NMR methodologies.
- Author
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Jiménez Barbero, Jesús, Airoldi, Cristina, Química Orgánica e Inorgánica, Kimika Organikoa eta Ez-Organikoa, Bertuzzi, Sara, Jiménez Barbero, Jesús, Airoldi, Cristina, Química Orgánica e Inorgánica, Kimika Organikoa eta Ez-Organikoa, and Bertuzzi, Sara
- Abstract
274 p., Glycans are ubiquitous in Nature. They are mainly found conjugated with other biomolecules giving rise to glycoproteins and glycolipids. Relevant biological events such as cell-cell, cell-matrix and host-pathogen interactions are orchestrated through the recognition of glycans by a group of specific proteins, called lectins. Several sub-families of lectins can be differentiated, being galectins, C-type lectins, and siglecs the most studied and suitable for biomedical applications.In this Thesis, different lectin-sugar systems have been selected and the fine details of their binding events have been decoded from the structural, conformational, and dynamic points of view. Particular attention to aspects such as conformational motions, multivalency, presentation, and the actual in-vitro or cell-like environment were the driving force behind this work.
- Published
- 2024
6. Carbohydrates in the Body and Functions
- Author
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Shiv Sanjeevi Sripathi and Shiv Sanjeevi Sripathi
- Subjects
- Carbohydrates, Glucides
- Abstract
Carbohydrates are present in whole grains and potatoes, as well as, other sources. Apart from providing a quick source of energy (remember the rejuvenating effect of glucose –based drinks or eating a fruit?), these molecules assume several roles in organisms. The roles include structural strength (cellulose and pectin), signaling, host-pathogen interactions (glycoproteins), and even as treatment approaches. As far as their intake is concerned, researchers suggest that more than the quantity or the percentage of carbohydrates consumed, the quality is important. Amongst the various carbohydrate sources, the consumption of whole grains is recommended along with legumes that contain other nutrients like proteins. We believe that the readers find this book informative as information on all aspects of carbohydrates has been compiled in this single book.
- Published
- 2020
7. Glycan-Based Cellular Communication: Techniques for Carbohydrate-Protein Interactions
- Author
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Peng George Wang, Cheng Ma, Shukkoor Muhammed Kondengaden, Eugene Joeh, Zak Vilen, Timothy O’Leary, Mia L. Huang, Jeffrey C. Gildersleeve, John Faulkner, Xuehong Song, Lianchun Wang, James Hooper, Yuan Guo, Dejian Zhou, Zachary Klamer, Brian Haab, Abdul Rehman, Lei Li, Xiangqun Zeng, Sheng-Ce Tao, Shumin Zhou, Siavash Mashayekh, Elizabeth A. D’Ambrosio, Catherine L. Grimes, Dong-Kyu Kim, Sungjin Park, He Zhu, Arya Aloor, Shukkoor M. Kondengaden, Peng George Wang, Cheng Ma, Shukkoor Muhammed Kondengaden, Eugene Joeh, Zak Vilen, Timothy O’Leary, Mia L. Huang, Jeffrey C. Gildersleeve, John Faulkner, Xuehong Song, Lianchun Wang, James Hooper, Yuan Guo, Dejian Zhou, Zachary Klamer, Brian Haab, Abdul Rehman, Lei Li, Xiangqun Zeng, Sheng-Ce Tao, Shumin Zhou, Siavash Mashayekh, Elizabeth A. D’Ambrosio, Catherine L. Grimes, Dong-Kyu Kim, Sungjin Park, He Zhu, Arya Aloor, and Shukkoor M. Kondengaden
- Subjects
- Cochlea, Ligands, Glycosylation, Membranes (Biology), Carbohydrates, Glycoproteins, Glucides, Cell interaction
- Published
- 2020
8. Carbohydrate Chemistry : Chemical and Biological Approaches Volume 43
- Author
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Amelia Pilar Rauter, Thisbe Lindhorst, Yves Queneau, Amelia Pilar Rauter, Thisbe Lindhorst, and Yves Queneau
- Subjects
- Carbohydrates, Glucides
- Abstract
Demonstrating the interdisciplinary nature of modern glycosciences, this volume covers research in the fields of polysaccharides and small carbohydrates from the synthetic and structural viewpoints, with applications ranging from biology to the bioeconomy. Key aspects of the synthesis and properties of imino disaccharides and regioselective glycosylation reactions are reviewed, glycosyltransferase inhibitors are shown to be potential future therapeutic agents, protein-carbohydrate interactions in plant cell-wall biodegradation are targeted by the use of glycan microarrays, biological properties of polysaccharidic microbial surface antigens are discussed with respect to their intimate structure, and contributions on carbohydrate-based hydrogelators, green/blue sugar-based surfactants and carbohydrate-based green solvents illustrate the modern design of tomorrow's chemicals. With the increase in volume, velocity and variety of information, researchers can find it difficult to keep up to date with the literature in their field and this book remains a valuable addition to any researcher's library.
- Published
- 2018
9. Gene expression analysis method integration and co-expression module detection applied to rare glucide metabolism disorders using ExpHunterSuite.
- Author
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Jabato, Fernando M., Córdoba-Caballero, José, Rojano, Elena, Romá-Mateo, Carlos, Sanz, Pascual, Pérez, Belén, Gallego, Diana, Seoane, Pedro, Ranea, Juan A. G., and Perkins, James R.
- Subjects
- *
GENE expression , *GLUCIDES , *METABOLIC disorders , *CALCIUM channels , *NAIVE Bayes classification - Abstract
High-throughput gene expression analysis is widely used. However, analysis is not straightforward. Multiple approaches should be applied and methods to combine their results implemented and investigated. We present methodology for the comprehensive analysis of expression data, including co-expression module detection and result integration via data-fusion, threshold based methods, and a Naïve Bayes classifier trained on simulated data. Application to rare-disease model datasets confirms existing knowledge related to immune cell infiltration and suggest novel hypotheses including the role of calcium channels. Application to simulated and spike-in experiments shows that combining multiple methods using consensus and classifiers leads to optimal results. ExpHunter Suite is implemented as an R/Bioconductor package available from https://bioconductor.org/packages/ExpHunterSuite. It can be applied to model and non-model organisms and can be run modularly in R; it can also be run from the command line, allowing scalability with large datasets. Code and reports for the studies are available from https://github.com/fmjabato/ExpHunterSuiteExamples. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
10. Industrial Applications of Renewable Biomass Products : Past, Present and Future
- Author
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Silvia Nair Goyanes, Norma Beatriz D’Accorso, Silvia Nair Goyanes, and Norma Beatriz D’Accorso
- Subjects
- Glucides, Sustainable development, Carbohydrates, Biomedical materials, Polymers, Green chemistry
- Abstract
This book effectively links the latest scientific advances to current technological applications of polymers, mainly focusing on biodegradable polymers obtained from biomass. The individual chapters were written by academic and industry researchers alike, introducing readers to topics that have received little attention in the literature to date. Key topics covered include polymers used in various areas such as food packaging, pharmaceuticals, energy production and the cosmetics industry, as well as the treatment of aqueous effluents.
- Published
- 2017
11. Advances in Carbohydrate Chemistry and Biochemistry
- Author
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Baker, David C. and Baker, David C.
- Subjects
- Biochemistry, Carbohydrates, Glucides
- Abstract
Advances in Carbohydrate Chemistry and Biochemistry has provided, since its inception in 1945, critical and informative articles written by research specialists that integrate the industrial, analytical, and technological aspects of biochemistry, organic chemistry, and instrumentation methodology to the study of carbohydrates. Its articles present a definitive interpretation of the current status and future trends in carbohydrate chemistry and biochemistry. - Features contributions from leading authorities and industry experts who specialize in carbohydrate chemistry, biochemistry, and research - Integrates the industrial, analytical, and technological aspects of biochemistry, organic chemistry, and instrumentation methodology in the study of carbohydrates - Informs and updates on all the latest developments in the field
- Published
- 2016
12. Glucides : Les Grands Articles d'Universalis
- Author
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Encyclopaedia Universalis and Encyclopaedia Universalis
- Subjects
- Carbohydrates, Glucides
- Abstract
Les glucides, les lipides et les protides sont les trois grandes familles de composés naturels dont le rôle biologique est fondamental. Glucides est le nom moderne de ce que l'on appelait autrefois « saccharides ». En fait, les glucides comprennent, outre des matières naturelles sucrées, dont le...
- Published
- 2016
13. EVALUATION OF TIGERNUT ACCESSIONS IN GHANA FOR PROXIMATE AND MINERAL COMPOSITION.
- Author
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DONKOR, E. F., NYADANU, D., and DAPAAH, H. K.
- Subjects
- *
YELLOW nutsedge , *MINERALS , *GROWING season , *CARBOHYDRATES - Abstract
Tigernut (Cyperus esculentus L.) is a nutritious, yet underutilised crop in Ghana. The objective of this study was to characterise Ghanaian tigernut accessions for proximate and mineral composition, as a guide for breeders for varietal development. Field and laboratory studies were conducted on 24 tigernut accessions from major growing areas of Ghana. The accessions were cultivated during the minor the growing season (September - November), at the Multipurpose Nursery of the University of Education, Winneba, Asante Mampong in Ghana. The nuts were analysed for proximate (carbohydrate, energy, moisture, ether extract, crude fiber, crude protein and ash) and mineral (potassium, phosphorus and calcium) composition. There were significant (P<0.05) differences among accessions for all traits studied. Accessions were clustered in a dendrogram by colour and geographical origin and PC1 and PC2 explained more than 80% of the total variations among the accessions, with carbohydrate and energy being the major contributors to the total variation. Accessions DY, BKB, KAB, TPY, CCY, WY2 and WY1, which recorded high levels of proximate and mineral compositions, may be considered for breeding programmes to provide high nutrient varieties of tigernut in Ghana. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
14. Advances in Carbohydrate Chemistry and Biochemistry
- Author
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David C. Baker, Derek Horton, David C. Baker, and Derek Horton
- Subjects
- Biochemistry, Carbohydrates, Glucides
- Abstract
Advances in Carbohydrate Chemistry and Biochemistry, part of a long running serial that began in 1945, provides critical and informative articles written by research specialists that integrate the industrial, analytical, and technological aspects of biochemistry, organic chemistry, and instrumentation methodology in the study of carbohydrates. Each article provides a definitive interpretation of the current status and future trends in carbohydrate chemistry and biochemistry. - Features contributions from leading authorities and industry experts who specialize in carbohydrate chemistry, biochemistry, and research - Integrates the industrial, analytical, and technological aspects of biochemistry, organic chemistry, and instrumentation methodology in the study of carbohydrates - Informs and updates on all the latest developments in the field
- Published
- 2015
15. Carbohydrate mouth rinse effects on physical and cognitive performance: Benefits and limitations in sports.
- Author
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Pomportes, L. and Brisswalter, J.
- Subjects
- *
CARBOHYDRATES , *GASTROINTESTINAL system , *PHYSICAL activity , *QUALITY of life , *QUESTIONNAIRES - Abstract
During the last decade, it has been suggested that the benefits of oral carbohydrates during short and high intensity exercise < 1 h , ≥ 75 % V ˙ O 2 max are likely related to a central action probably mediated by receptors in the mouth and in the gastrointestinal tract. Interestingly, when individuals rinsed their mouths with a carbohydrate solution, afferent neural signals activate several brain areas enabling to modify motor output. Experimental studies report a 2–3% of physical performance enhancement during exercise shorter than 1 h. A beneficial effect on high-intensity intermittent exercise has also been reported, specifically in the late bouts of exercise. Moreover, several benefits related to cognition have been suggested. Rating of perceived exertion as well as motor skill-specific during exercise may be enhanced, which could provide a substantial performance improvement. Finally, carbohydrate mouth rinsing appears to be an interesting nutritional strategy in a wide range of sports. [ABSTRACT FROM AUTHOR]
- Published
- 2020
- Full Text
- View/download PDF
16. Deciphering the recognition features of glycans by human lectins at the molecular level
- Author
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Jiménez Barbero, Jesús, Ereño Orbea, June, Bioquímica y biología molecular, Biokimika eta biologia molekularra, Lenza, Maria Pia, Jiménez Barbero, Jesús, Ereño Orbea, June, Bioquímica y biología molecular, Biokimika eta biologia molekularra, and Lenza, Maria Pia
- Abstract
200 p., Carbohydrates are one of the most variable and complex molecules of biological systems. They areusually located at the cell membrane, mainly as glycoconjugates, glycoproteins or glycolipids and play an important role in the specific molecular recognitions. Since structure and function are intrinsically correlated, the three-dimensional shape, dynamics and presentation of these molecules is essential for the recognition processes to take place.In this work, we have employed a combination of X-Ray crystallography and Nuclear Magnetic Resonance spectroscopy (NMR) techniques, for obtaining atomic-scale information on the interactions of glycans and glycomimetics, using either intact glycoproteins (the receptor binding domain of the spikegly coprotein of SARS CoV2) or small molecules, with different receptors related to human diseases, with special emphasis on galectins and siglecs (immune response). The presented methodology allows disentangling the fine details of the vital glycan epitopes, providing key information for the developmentof novel therapeutics.
- Published
- 2023
17. Characterization of environment-related endophenotypes in pulmonary hypertension
- Author
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Berra Ramírez, Miren Edurne, Ruiz-Cabello Osuna, Jesús María, Bioquímica y biología molecular, Biokimika eta biologia molekularra, Fadón Padilla, Lucía, Berra Ramírez, Miren Edurne, Ruiz-Cabello Osuna, Jesús María, Bioquímica y biología molecular, Biokimika eta biologia molekularra, and Fadón Padilla, Lucía
- Abstract
176 p., La hipertensión pulmonar (HP) es una condición compleja caracterizada por un incremento de la presión en las arterias de los pulmones, que puede dañar el lado derecho del corazón. Clásicamente se define por unos valores de presión arterial pulmonar media ¿25 mmHg. Con mayor frecuencia, la HP aparece como secuela de otra enfermedad, excepto en el caso de la HP del grupo I, hipertensión arterial pulmonar (HAP), que cursa con remodelación vascular pulmonar e incremento de la resistencia. El ventrículo derecho (VD) aumenta la fuerza de contracción para mantener el flujo sanguíneo, lo que acaba provocando su hipertrofia, y finalmente insuficiencia cardíaca. A nivel mundial se estima que casi el 1% de la población sufre de HP. A pesar de ello, sigue siendo una enfermedad mortal. Los síntomas incluyen dificultad respiratoria, fatiga, dolor en el pecho, aumento de la frecuencia cardíaca, y en casos más avanzados, mareos, síncopes y edema. Los principales métodos de diagnóstico comprenden el ecocardiograma como herramienta de cribado no invasiva y el cateterismo cardíaco derecho para establecer un diagnóstico definitivo. Dada la importancia del diagnóstico precoz en el manejo de la enfermedad, se necesita más investigación para refinar una técnica no invasiva y específica, capaz de detectar la HP en una etapa temprana. Como aún no hay cura, la terapia se dirige a paliar los síntomas y retrasar la progresión de la enfermedad. En este sentido, las intervenciones en el estilo de vida están ganando relevancia como tratamiento de apoyo de la enfermedad, entre las que se incluye la práctica de ejercicio físico. Sin embargo, sigue habiendo muchos aspectos desconocidos de la HP, y, a pesar de los avances, la falta de comprensión de la enfermedad puede obstaculizar la cura. Nos hemos centrado en algunos elementos clave de la patogénesis de la HAP, como la inflamación, la hipoxia y las alteraciones metabólicas, con el fin de analizar cómo afectan a la patología. La tesis se divide en
- Published
- 2023
18. Advances in Food and Nutrition Research
- Author
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Kim, Se-Kwon and Kim, Se-Kwon
- Subjects
- Marine biotechnology, Carbohydrates, Glucides
- Abstract
Advances in Food and Nutrition Research recognizes the integral relationship between the food and nutritional sciences and brings together outstanding and comprehensive reviews that highlight this relationship. Contributions detail scientific developments in the broad areas of food science and nutrition and are intended to provide those in academia and industry with the latest information on emerging research in these constantly evolving sciences. - The latest important information for food scientists and nutritionists - Peer-reviewed articles by a panel of respected scientists - The go-to series since 1948
- Published
- 2014
19. Nanomaterials in Glucose Sensing
- Author
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Krishna Burugapalli, Ning Wang, Krishna Burugapalli, and Ning Wang
- Subjects
- Carbohydrates, Monosaccharides, Glucides, Blood glucose, Nanomedicine, Glucose tolerance tests, Glucose, Manufactures, Dextrose
- Abstract
The smartness of nano-materials is attributed to their nanoscale and subsequently unique physicochemical properties and their use in glucose sensing has been aimed at improving performance, reducing cost and miniaturizing the sensor and its associated instrumentation. So far, portable (handheld) glucose analysers were introduced for hospital wards, emergency rooms and physicians'offices; single-use strip systems achieved nanolitre sampling for painless and accurate home glucose monitoring; advanced continuous monitoring devices having 2 to 7 days operating life are in clinical and home use; and continued research efforts are being made to develop and introduce increasingly advanced glucose monitoring systems for health as well as food, biotechnology, cell and tissue culture industries. Nanomaterials have touched every aspect of biosensor design and this chapter reviews their role in the development of advanced technologies for glucose sensing, and especially for diabetes. Research shows that overall, nanomaterials help address the problems with conventional optical and electrochemical biosensors, by enhancing the preferential detection of glucose or its oxidation products through better electron transfer kinetics, sensitivity and response time, while lowering the operating over-voltages for energy efficiency and avoid interference. The reproducible production of nano-materials and nano-structures at low cost is vital for the successful development of nano-technologies for glucose sensing. Several products, especially, home glucose monitoring devices, use nano-materials, but the need for reliable long-term CGM is still unmet. Nano-materials and nano-technologies have an important role in achieving the long-awaited CGM technology.
- Published
- 2014
20. Marine Carbohydrates: Fundamentals and Applications, Part A
- Author
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Kim, Se-Kwon and Kim, Se-Kwon
- Subjects
- Carbohydrates, Glucides
- Abstract
Marine Carbohydrates: Fundamentals and Applications brings together the diverse range of research in this important area which leads to clinical and industrialized products. The volume, number 72, focuses on marine carbohydrates in isolation, biological, and biomedical applications and provides the latest trends and developments on marine carbohydrates. Advances in Food and Nutrition Research recognizes the integral relationship between the food and nutritional sciences and brings together outstanding and comprehensive reviews that highlight this relationship. Volumes provide those in academia and industry with the latest information on emerging research in these constantly evolving sciences. - Includes the isolation techniques for the exploration of the marine habitat for novel polysaccharides - Discusses biological applications such as antioxidant, antiallergic, antidiabetic, antiobesity and antiviral activity of marine carbohydrates - Provides an insight into present trends and approaches for marine carbohydrates
- Published
- 2014
21. Dauerhaftigkeit von Beton
- Author
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Jochen Stark, Bernd Wicht, Jochen Stark, and Bernd Wicht
- Subjects
- Carbohydrates, Engineering, Building construction, Glucides
- Abstract
Dieses Buch befasst sich mit den Größen und Einflüssen, die für die Dauerhaftigkeit des Baustoffs Beton von Bedeutung sind. Zahlreiche Bilder eröffnen praxisorientierte Einblicke in die werkstoffkundlichen Vorgänge. Kenngrößen und Einflussfaktoren auf die Dauerhaftigkeit von Beton – Zement – Carbonatisierung - Sulfatangriff – schädigende Ettringitbildung im erhärteten Beton – Säureangriff – Einwirkung von Chloriden – Alkali-Kieselsäure-Reaktion – Frost- und Frosttausalz-Widerstand.
- Published
- 2013
22. Carbohydrate Chemistry & Stereochemistry
- Author
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Harrison Sheldon, Sherry Goins, Harrison Sheldon, and Sherry Goins
- Subjects
- Stereochemistry, Carbohydrates, Glucides
- Abstract
Chapter 1 - Architectural Engineering Chapter 2 - Structural Engineering Chapter 3 - Building Services Engineering Chapter 4 - Building Automation Chapter 5 - Home Automation Chapter 6 - Building Information Modeling Chapter 7 - Building Material Chapter 8 - Construction Chapter 9 - HVAC Chapter 10 - Damp (Structural) Chapter 11 - Fracture Chapter 12 - Dry Rot Chapter 13 - Dry Rot Treatment Chapter 14 - Architectural Acoustics Chapter 15 - Liquid Metal Embrittlement Chapter 16 - Structural Failure Chapter 17 - Thermal Expansion Chapter 18 - Piping and Plumbing Fittings
- Published
- 2012
23. Carbohydrate Chemistry
- Author
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Sherry Goins and Sherry Goins
- Subjects
- Carbohydrates, Glucides
- Abstract
Chapter 1 - Carbohydrate Chemistry Chapter 2 - Monosaccharide Chapter 3 - Carbohydrate Synthesis Chapter 4 - Reactions of Carbohydrates Chapter 5 - Carbohydrate Structure Chapter 6 - Carbohydrate Conformation and Protein-carbohydrate Interactions Chapter 7 - Anomer Chapter 8 - Glycal and Glycan Chapter 9 - Crich Beta-mannosylation and Glycomics Chapter 10 - Glycoside Hydrolase and Glycopeptide Chapter 11 - Intramolecular Aglycon Delivery Chapter 12 - Monosaccharide Nomenclature
- Published
- 2012
24. Advances in Carbohydrate Chemistry and Biochemistry
- Author
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Derek Horton and Derek Horton
- Subjects
- Carbohydrates, Glucides
- Abstract
Since its inception in 1945, this serial has provided critical and integrating articles written by research specialists that integrate industrial, analytical, and technological aspects of biochemistry, organic chemistry, and instrumentation methodology in the study of carbohydrates. The articles provide a definitive interpretation of the current status and future trends in carbohydrate chemistry and biochemistry. - Features contributions from leading authorities and industry experts - Informs and updates on all the latest developments in the field
- Published
- 2012
25. Carbohydrate-Modifying Biocatalysts
- Author
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Peter Grunwald and Peter Grunwald
- Subjects
- Glucides, Carbohydrates, Enzymes
- Abstract
Carbohydrates have long been disregarded by the scientific community due to their complex structure and a lack of suitable experimental methods for structure determination. This book provides an overview of the structure, function, and application of carbohydrate-modifying biocatalysts. It explores glycoconjugates and carbohydrate-modifying enzymes
- Published
- 2012
26. Carbohydrate Chemistry : Volume 38
- Author
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Amelia Pilar Rauter, Thisbe Lindhorst, Amelia Pilar Rauter, and Thisbe Lindhorst
- Subjects
- Carbohydrates, Glucides
- Abstract
In this volume, glycochemistry and glycobiology have been combined to demonstrate the contribution of organic chemistry, modern analytics, biological and biochemical expertise to the increasingly important field of glycomincs. A polysaccharide immunomodulator with therapeutic implications, carbohydrate vaccines, new findings emphasizing the influence of carbohydrate decoration on the regulation of inflammatory response and new therapeutic approaches in the treatment of acute and chronic inflammatory diseases, recent approachesin the treatment of acute and chronic inflammatory diseases, recent progress on glycoengineering based on a glycosylation, and key aspects of the glycosylation changes associated with bladder cancer are amongst the subjects presented in this volume. The contribution of glycochemistry to innovation in glycosciences is shown with chapters covering highly functionalized exo-glycals for the generation of molecular diversity in a chemoselective manner, imino sugar glycosidase inhibitors, carbasugars, multivalent glycoconjugates, including glycodendrimers, glyconanotubes, and glyconanoparticles, and their uses in medicinal chemistry, as well as artificial saccharide-based and saccharide functionalized gene delivery systems. Siderphores based on monosaccharides (which have proven effective for Gram-negative bacteria and mycobacteria), and the so-called smart materials, (which can modulate and control cell behaviour), complete the volume. Volume 38 of Carbohydrate Chemistry - Chemical and Biological Apporaches contains contributions ranging from glycochemistry to glycobiology. This collection demonstrates in a meaningful way how the interdisciplinary approach of an international glyconetwork can advance the field of carbohydrate research in Europe and worldwide.
- Published
- 2012
27. EFFECTIVENESS OF PRUNING AND WAXING IN REDUCING POSTHARVEST PHYSIOLOGICAL DETERIORATION IN UGANDA LOCAL CASSAVA VARIETIES.
- Author
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NUWAMANYA, E., ACHENG, S., VUZI, P., MUYINZA, H., MATOVU, M., ATWIJUKIRE, E., MENYA, G., WANDA, K., NYAKAISIKI, E., and ADEBAYO, B. A.
- Subjects
- *
CASSAVA , *CULTIVARS , *PRUNING , *STARCH - Abstract
Cassava (Manihot esculenta Crantz) roots in the fresh form, are susceptible to postharvest physiological deterioration (PPD), thus reducing their economic value and farmer benefits. The objective of this study was to evaluate the effectiveness of pruning and waxing on fresh root storability among cassava varieties in Uganda. Sixteen cassava plants per variety (TME 14, NASE 14, Nyaraboke, Kirimumpale, and Bukalasa) were pruned seven days before harvest, leaving the rest as unpruned controls. After harvest, roots were divided into two portions and one portion was waxed using food grade wax. Pruning alone reduced PPD of stored roots by 23% at day 14 of storage; and by 19% at day 28 compared with the control. Pruning as a treatment resulted into increased sugar content, ranging 9- 30%), and significant (P<0.05) losses in starch yield. Pruning combined with waxing, resulted in a reduction of up to 43% in PPD by day 14, and up to 67 at day 28. Reduction in carbohydrate (starch) was not significant (P>0.05) under the pruning and waxing treatment, which had minor effects on stored root composition. The results indicate that pruning is appropriate for the short-term storage of fresh cassava roots for up to 14 days. Waxing, combined with pruning, is suitable for longer term storage up to 28 days under Uganda conditions. [ABSTRACT FROM AUTHOR]
- Published
- 2019
- Full Text
- View/download PDF
28. NUTRITIONAL AND ANTIOXIDANT COMPOSITION OF EGGPLANT ACCESSIONS IN GHANA.
- Author
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AFFUL, N. T., NYADANU, D., AKROMAH, R., AMOATEY, H. M., ANNOR, C., and DIAWOUH, R. G.
- Subjects
- *
EGGPLANT , *MULTIPLE correspondence analysis (Statistics) , *GALLIC acid , *ANTIOXIDANT analysis , *ANTIOXIDANTS , *NUTRITIONAL value - Abstract
Eggplants (Solanum spp.) are important vegetable crops, well known for nutritional and medicinal values of their fruits and leaves. In order to select more nutritious varieties in Ghana, 33 eggplant accessions were investigated for nutritional, mineral and antioxidant content of their fruits. Proximate and antioxidant analysis were determined by AOAC and DPPH methods. The results showed significant differences (P<0.05) among nutritional, mineral and antioxidant traits. Most accessions contained high moisture content (above 70%). Nutrient concentrations ranged from 0.10 fat to 6.10 g 100 g-1 carbohydrate; and 0.107 magnesium to 11.271 mg 100 g-1 iron. Total phenolic content was highest in accession ST004-03 (210 mg GAE g-1 (gallic acid equivalent), and lowest in SA002-02 (171.10 mg GAE g-1). Accessions ST004-02 and ST004-03 displayed the highest DPPH (2, 2-diphenyl-1-picrylhydrazyl) radical scavenging activity (0.017 mg ml-1); while San 005-01 (1474 mg ml-1) showed the highest antioxidant content. Principal component analysis indicated that the first 3 components with Eigen value >1.5 contributed 68.68% of total variability. Dry matter, protein, moisture and carbohydrate contents showed maximum contributions to the total variability. Biplot analysis displayed strong and positive associations among ash, protein and moisture with dry matter; moisture and carbohydrate and; protein and ash. Accessions San 005-01, San 005-02, SA 002-07, SA 002-08 and ST004-03 were identified as good sources of nutrients, minerals and antioxidant properties among the others; and could be used as potential donors for hybridisation programme to develop varieties with higher concentration of these traits. [ABSTRACT FROM AUTHOR]
- Published
- 2019
- Full Text
- View/download PDF
29. ECOTOXICOLOGICAL ASSESSMENT OF SOME ORANGE JUICES MARKETED IN ROMANIA.
- Author
-
CIOBOTARU, Nicoleta and BURTEA, Mariana Carmen
- Subjects
- *
ENVIRONMENTAL toxicology , *ORANGE juice , *VITAMIN C , *HUMIDITY - Abstract
This paper presents a comparative ecotoxicological study, performed on several orange juices sold in Romania and on a freshly orange juice prepared from the fruit. For each juice sample, quality parameters such as pH, carbohydrate content, dry matter and humidity were analyzed. The presence of the food additive ascorbic acid (vitamin C) was also studied. The obtained results revealed the similarities and differences between the natural juice and the studied commercial juices. [ABSTRACT FROM AUTHOR]
- Published
- 2019
30. A Multiscale Study of Phosphorylcholine Driven Cellular Phenotypic Targeting
- Author
-
Silvia Acosta-Gutiérrez, Diana Matias, Milagros Avila-Olias, Virginia M. Gouveia, Edoardo Scarpa, Joe Forth, Claudia Contini, Aroa Duro-Castano, Loris Rizzello, and Giuseppe Battaglia
- Subjects
Bioquímica ,Science & Technology ,PH ,Chemistry, Multidisciplinary ,General Chemical Engineering ,Glúcids ,SR-BI ,MULTIVALENCY ,General Chemistry ,Biochemistry ,Chemistry ,Glucides ,B TYPE-I ,Physical Sciences ,BINDING ,CD36 ,03 Chemical Sciences ,SCAVENGER RECEPTOR - Abstract
Phenotypic targeting requires the ability of the drug delivery system to discriminate over cell populations expressing a particular receptor combination. Such selectivity control can be achieved using multiplexed-multivalent carriers often decorated with multiple ligands. Here, we demonstrate that the promiscuity of a single ligand can be leveraged to create multiplexed-multivalent carriers achieving phenotypic targeting. We show how the cellular uptake of poly(2-methacryloyloxyethyl phosphorylcholine)-poly(2- (diisopropylamino)ethyl methacrylate) (PMPC-PDPA) polymersomes varies depending on the receptor expression among different cells. We investigate the PMPC-PDPA polymersome insertion at the single chain/receptor level using all-atom molecular modelling. We propose a theoretical statistical mechanics-based model for polymersome-cell association that explicitly considers the interaction of the polymersome with the cell glycocalyx shedding light on its effect on the polymersome binding. We validate our model experimentally and show that the binding energy is a non-linear function, allowing us to tune interaction by varying the radius and degrees of polymerisation. Finally, we show that PMPC-PDPA polymersomes can be used to target monocytes in vivo due to their promiscuous interaction with SRB1, CD36 and CD81.
- Published
- 2022
31. Advances in Carbohydrate Chemistry and Biochemistry
- Author
-
Derek Horton and Derek Horton
- Subjects
- Biochemistry, Carbohydrates, Glucides
- Abstract
Since its inception in 1945, this serial has provided critical and integrating articles written by research specialists that integrate industrial, analytical, and technological aspects of biochemistry, organic chemistry, and instrumentation methodology in the study of carbohydrates. The articles provide a definitive interpretation of the current status and future trends in carbohydrate chemistry and biochemistry. - Features contributions from leading authorities and industry experts - Informs and updates on all the latest developments in the field
- Published
- 2011
32. Glycobiology
- Author
-
Minoru Fukuda and Minoru Fukuda
- Subjects
- Metabolism, Glucides, Glycomics, Carbohydrates, Glycosylation
- Abstract
In this 3 volume collection focusing on glycomics, readers will appreciate how such discoveries were made and how such methods can be applied for readers'own research efforts - Each chapter has been designed so that enough scientific background will be given in each chapter for further development of methods by readers themselves - Useful for all levels of scientists starting from the last years of colleges, graduate students, postdoctoral fellows to professors and to all levels of scientists in research institutes including industry
- Published
- 2010
33. Glycomics
- Author
-
Fukuda, Minoru and Fukuda, Minoru
- Subjects
- Metabolism, Glucides, Glycomics, Carbohydrates, Glycosylation
- Abstract
In this 3 volume collection focusing on glycomics, readers will appreciate how such discoveries were made and how such methods can be applied for readers'own research efforts - Each chapter has been designed so that enough scientific background will be given in each chapter for further development of methods by readers themselves - Useful for all levels of scientists starting from the last years of colleges, graduate students, postdoctoral fellows to professors and to all levels of scientists in research institutes including industry
- Published
- 2010
34. Functional Glycomics
- Author
-
Minoru Fukuda and Minoru Fukuda
- Subjects
- Metabolism, Glucides, Glycomics, Carbohydrates, Glycosylation
- Abstract
In this 3 volume collection focusing on glycomics, readers will appreciate how such discoveries were made and how such methods can be applied for readers'own research efforts - Each chapter has been designed so that enough scientific background will be given in each chapter for further development of methods by readers themselves - Useful for all levels of scientists starting from the last years of colleges, graduate students, postdoctoral fellows to professors and to all levels of scientists in research institutes including industry
- Published
- 2010
35. Zuckersüße Chemie : Kohlenhydrate and Co
- Author
-
Georg Schwedt and Georg Schwedt
- Subjects
- Carbohydrates, Glucides
- Abstract
This is a potpourri of information, recipes and chemical experiments involving sugar. Georg Schwedt, one of the most experienced authors of practical experiment books, clearly explains the topic, yet in an unusual way - a treasure trove of stories, tips and experiments. Suitable for chemistry, biology and biochemistry courses in all types of schools as well as at universities.
- Published
- 2010
36. Effects of honey on exercise performance and health components: A systematic review.
- Author
-
Yusof, A., Ahmad, N.S., Hamid M.S., A., and Khong, T.K.
- Subjects
- *
HONEY , *EXERCISE , *HEALTH promotion , *IMMUNE system , *ENDURANCE sports - Abstract
Summary Introduction Honey consists mainly of carbohydrates (CHO), minerals, and vitamins which are properties that are believed able to improve exercise performance and general health. This review aimed to elucidate findings on the effects of honey on exercise performance as well as combined effects of honey and exercise on health-related outcomes. Methods Literature was searched systematically based on PRISMA guidelines, using PubMed, Science Direct, SPORTDiscus and Web of Science databases. Thirteen human and animal studies were included in the final analysis. Surprisingly, there were only three randomised-controlled studies that investigated the effect of honey on exercise performance per se, meanwhile, ten reported the combined effects of honey and exercise on bone health, hormones, immune system, and inflammation. Acute honey ingestion improved endurance performance in two studies, while, five studies reported improvements in bone health after consuming honey combined with jumping exercises or aerobic dance. One study reported that stress and reproductive hormones were positively regulated. Five studies reported increase in white blood cells and neutrophils after ingesting honey combined with resistance or aerobic exercises which boosted the immune system. Conclusion Honey alone could potentially improve aerobic exercise performance; however studies are limited. Meanwhile, honey in combination with exercise promotes bone health and improves immune systems. It is believed that CHO and other constituents of honey play an important role during exercise in exerting the said benefits. [ABSTRACT FROM AUTHOR]
- Published
- 2018
- Full Text
- View/download PDF
37. EFFECT OF RHIZOGENIC BIOSTIMULATORS ON ROSMARINUS OFFICINALIS ROOTED CUTTINGS BIOCHEMICAL COMPOSITION.
- Author
-
VÂȘCĂ-ZAMFIR, Diana, BĂLAN, Daniela, LUŢĂ, Gabriela, and GHERGHINA, Evelina
- Subjects
ROSEMARY ,GREENHOUSES ,ROOT growth ,GLUCIDES ,CHEMICAL composition of plants - Abstract
Originally from the Mediterranean area, Rosmarinus officinalis (Fam. Lamiaceae) is a species widespread in most temperate regions of Europe and America with a significant economic impact due to the trivalent effect (ornamental, aromatic and medicinal). The purpose of these researches was to evaluate the impact of rhizogenic biostimulator Clonex-gel treatments on the rooting potential and some biochemical parameters of different types of cuttings in greenhouse conditions. The experiments carried out in the HORTINVEST greenhouses of USAMV Bucharest aimed to evaluate the rooting percentage, the development of the root system and the aerial part after rooting. Also, some biochemical parameters (assimilatory pigments and total soluble sugars content) were analyzed to assess the potential effect of the substances used to stimulate rooting on the biochemical composition of leaves formed on cuttings. The researches performed indicated that maximum percentage of rooting cuttings was determined in treated variants. The stimulation of the roots growth determined also an increased accumulation of assimilatory pigments and soluble glucids in the leaves. [ABSTRACT FROM AUTHOR]
- Published
- 2018
38. NMR studies of the interactions of glycan antigens with monoclonal antibodies.
- Author
-
Sotomayor Anduiza, María Nuria, Reichardt, Niels Christian, Jiménez Barbero, Jesús, Química orgánica II, Kimika organikoa II, Calloni, Ilaria, Sotomayor Anduiza, María Nuria, Reichardt, Niels Christian, Jiménez Barbero, Jesús, Química orgánica II, Kimika organikoa II, and Calloni, Ilaria
- Abstract
123 p. Los capítulos: 2.3.2, 2.3.3, 2.3.4, 2.3.5, 2.4, 3.3.3, 3.3.4, 3.3.5, y 3.4 están sujetos a confidencialidad por la autora, Carbohydrates are one of the most variable and complex molecules of biological systems. They are usually located at the cell membrane, mainly as glycoconjugates, glycoproteins or glycolipids and play an important role in the specific molecular recognitions. Within glycans, polysaccharide capsules (CPS) are universal structures found on the cell surface of a broad range of bacterial species and often constitute the outermost layer of the cell; as such, they mediate the direct interactions between the bacterium and its immediate environment. Since structure and function are intrinsically correlated, the three-dimensional shape, dynamics and presentation of these molecules play a role in the recognition processes.In this work, we have employed a variety of Nuclear Magnetic Resonance spectroscopy (NMR) techniques, assisted by different computational approaches, in particular Molecular Dynamics (MD) simulation and ab initio methods, for obtaining atomic-scale information on the conformation, dynamics and interactions, in solution, of different types of capsular polysaccharides present in Neisseria meningitis and Streptococcus B.
- Published
- 2022
39. Insights into HMF catalysis
- Author
-
Portillo Perez, Guillermo, Mukherjee, Agneev, Dumont, Marie-Josée, Portillo Perez, Guillermo, Mukherjee, Agneev, and Dumont, Marie-Josée
- Abstract
In recent decades, the concept of biorefinery has gained considerable momentum as a promising approach to obtain energy commodity chemicals. 5-hydroxymethylfurfural (HMF) is one of the most promising building blocks for biobased chemicals and a strong candidate for large scale production. However, one of the main factors holding its transition is the need for green, sustainable, and financially feasible processes. This review provides a critical assessment of the progresses made towards catalytic and autocatalytic systems used for HMF production, as well as advancements in catalyst research, their mechanisms analyses, efficiency and sustainability. It also provides key information which can facilitate the selection and development of catalysts for HMF production.
- Published
- 2022
40. The Sugar Code : Fundamentals of Glycosciences
- Author
-
Hans-Joachim Gabius and Hans-Joachim Gabius
- Subjects
- Carbohydrates, Glucides, Glycoconjugates, Glycosylation, Lectins
- Abstract
A reader friendly overview of the structure and functional relevance of natural glycosylation and its cognate proteins (lectins), this book is also one of the few books to cover their role in health and disease. Edited by one of the pioneering experts in the field and written by a team of renowned researchers this resource is a perfect introduction for all students in life and medical sciences, biochemistry, chemistry and pharmacy. Website: WWW.WILEY-VCH.DE/HOME/THESUGARCODE
- Published
- 2009
41. Carbohydrate Chemistry : Volume 35
- Author
-
Amelia Pilar Rauter, Thisbe Lindhorst, Amelia Pilar Rauter, and Thisbe Lindhorst
- Subjects
- Carbohydrates, Glucides
- Abstract
Carbohydrate Chemistry provides review coverage of all publications relevant to the chemistry of monosaccharides and oligosaccharides in a given year. The amount of research in this field appearing in the organic chemical literature is increasing because of the enhanced importance of the subject, especially in areas of medicinal chemistry and biology. In no part of the field is this more apparent than in the synthesis of oligosaccharides required by scientists working in glycobiology. Clycomedicinal chemistry and its reliance on carbohydrate synthesis is now very well established, for example, by the preparation of specific carbohydrate- based antigens, especially cancer-specific oligosaccharides and glycoconjugates. Coverage of topics such as nucleosides, amino-sugars, alditols and cyclitols also covers much research of relevance to biological and medicinal chemistry. Each volume of the series brings together references to all published work in given areas of the subject and serves as a comprehensive database for the active research chemist Specialist Periodical Reports provide systematic and detailed review coverage in major areas of chemical research. Compiled by teams of leading authorities in the relevant subject areas, the series creates a unique service for the active research chemist, with regular, in-depth accounts of progress in particular fields of chemistry. Subject coverage within different volumes of a given title is similar and publication is on an annual or biennial basis.
- Published
- 2009
42. Advances in Carbohydrate Chemistry and Biochemistry
- Author
-
Derek Horton and Derek Horton
- Subjects
- Carbohydrates, Biochemistry, Glucides
- Abstract
Since its inception in 1945, this serial has provided critical and integrating articles written by research specialists that integrate industrial, analytical, and technological aspects of biochemistry, organic chemistry, and instrumentation methodology in the study of carbohydrates. The articles provide a definitive interpretation of the current status and future trends in carbohydrate chemistry and biochemistry.
- Published
- 2009
43. The Subsistence and Foodways Transition during the Neolithization Process. Glimpses from a Contextualized Dental Perspective
- Author
-
Bocquentin, Fanny, Chamel, Bérénice, Anton, Marie, Noûs, Camille, Centre National de la Recherche Scientifique (CNRS), Ethnologie préhistorique, Archéologies et Sciences de l'Antiquité (ArScAn), Université Paris 1 Panthéon-Sorbonne (UP1)-Université Paris Nanterre (UPN)-Ministère de la Culture et de la Communication (MCC)-Centre National de la Recherche Scientifique (CNRS)-Université Paris 1 Panthéon-Sorbonne (UP1)-Université Paris Nanterre (UPN)-Ministère de la Culture et de la Communication (MCC)-Centre National de la Recherche Scientifique (CNRS), Bocquentin, Fanny, and Université Paris 1 Panthéon-Sorbonne (UP1)-Université Paris 8 Vincennes-Saint-Denis (UP8)-Université Paris Nanterre (UPN)-Ministère de la Culture et de la Communication (MCC)-Institut national de recherches archéologiques préventives (Inrap)-Centre National de la Recherche Scientifique (CNRS)-Université Paris 1 Panthéon-Sorbonne (UP1)-Université Paris 8 Vincennes-Saint-Denis (UP8)-Université Paris Nanterre (UPN)-Ministère de la Culture et de la Communication (MCC)-Institut national de recherches archéologiques préventives (Inrap)-Centre National de la Recherche Scientifique (CNRS)
- Subjects
Near East ,History ,[SHS.ARCHEO]Humanities and Social Sciences/Archaeology and Prehistory ,Primary data ,Postmortem loss ,[SHS.ANTHRO-BIO]Humanities and Social Sciences/Biological anthropology ,Carbohydrates ,Evolutionary Pattern ,Natufian ,Caries ,Natoufien ,Néolithique pré-céramique ,hypoplasie ,santé ,Levant ,pertes antemortem ,Pre-Pottery Neolithic ,2. Zero hunger ,[SHS.ARCHEO] Humanities and Social Sciences/Archaeology and Prehistory ,Correction factors ,Proche-Orient ,Néolithique céramique ,facteurs de correction ,tendances évolutives ,Hypoplasia ,Antemortem Loss ,pertes postmortem ,[SHS.ANTHRO-BIO] Humanities and Social Sciences/Biological anthropology ,3. Good health ,Abscesses ,glucides ,Health ,Pottery Neolithic ,abcès ,données primaires ,Food Science - Abstract
Les pathologies dentaires constituent un aspect important de la discussion sur la subsistance et les comportements alimentaires, notamment au moment de transitions alimentaires radicales. À la veille du processus de néolithisation au Levant, la période natoufienne (13000-9500 cal. BC) témoigne d’un nouveau mode d’approvisionnement associé à une diminution de la mobilité des groupes. De nouvelles denrées alimentaires apparaissent avec la production de plantes et l’élevage tout au long du Néolithique ancien (9500-6400 cal. BC). Cet article décrit les pathologies buccales spécifiques et non spécifiques liées à l’alimentation (lésions carieuses, pertes antemortem, abcès, résorptions alvéolaires) et les indicateurs de stress tels que l’hypoplasie linéaire de l’émail dentaire chez les populations du Natoufien et du Néolithique à partir d’un vaste corpus (plus de 8 600 dents) provenant de corpus bien contextualisés et qui ont été enregistrés par les présents auteurs selon les mêmes procédures. Les données quantitatives et qualitatives ont été analysées pour 24 sites à travers le Levant, attribués à différentes périodes et situés dans différents écosystèmes. Les résultats démontrent une nette augmentation des caries et des maladies associées au cours du processus de néolithisation. Il s’agit d’abord d’un processus graduel qui se met en place dès le Natoufien récent/final. Par la suite, le processus linéaire est rompu au 7e millénaire, période à laquelle de nouveaux comportements alimentaires semblent avoir été introduits dans la mesure où un nouveau schéma pathologique domine. Ces changements majeurs sont observés dans des contextes méditerranéens où la céramique n’est pas encore attestée. Un stress biologique élevé, lié au niveau socio-économique ou aux maladies infectieuses, est démontré en parallèle. Au fil du temps, l’alimentation semble de plus en plus sexuée mais moins spécifiquement associée aux groupes d’âge., Dental pathologies constitute an important topic for the discussion of subsistence and foodways, especially during periods of major shifts in dietary behaviour. On the eve of the Neolithization process in the Levant, the Natufian period (13000-9500 cal. BC) bears witnesses to a new way of food procurement associated with a decrease in group mobility. New foodstuffs appeared with plant production and husbandry throughout the Early Neolithic period (9500-6400 cal. BC). This article describes both specific and non-specific oral pathologies linked to diet (carious lesions, antemortem tooth loss, abscesses, alveolar resorption) and stress indicators such as Linear Enamel Hypoplasia among Natufian and Neolithic populations based on a huge corpus (over 8,600 teeth) of well contextualized samples that were recorded by the authors following the same procedures. Quantitative and qualitative information were analysed for 24 sites throughout the Levant, attributed to different periods and located in different ecosystems. The results demonstrate a clear increase in caries and associated diseases during the Neolithization process. This was first a gradual process that began as early as the Late/Final Natufian. The linear process was broken by the seventh millennium at which time new behaviours seem to have been introduced resulting in a new pathological pattern. The major changes at this time are observed in Mediterranean contexts where pottery is not yet attested. High biological stress, linked to socioeconomic level or infectious disease, is demonstrated in parallel. Over time, diet seems more and more gendered but less specifically associated with age groups.
- Published
- 2021
44. Carbohydrate Chemistry, Biology and Medical Applications
- Author
-
Hari G. Garg, Mary K. Cowman, Charles A. Hales, Hari G. Garg, Mary K. Cowman, and Charles A. Hales
- Subjects
- Carbohydrates in human nutrition, Glucides, Carbohydrates, Carbohydrates--Metabolism--Disorders
- Abstract
The finding by Emil Fischer that glucose and fructose on treatment with phenylhydrazine gave the identical osazone led him to the elucidation of stereochemistry of carbohydrates. Since then, progress in the field of carbohydrates has been amazing with the unraveling their basic structure, biosynthesis, immunology, functions, and clinical uses, for pure carbohydrates and for protein-linked carbohydrates (glycoproteins and proteoglycans). The chapters in Carbohydrate Chemistry, Biology and Medical Applications present a logical sequence leading from the chemistry and biochemistry of carbohydrates, followed by their role in various pathological conditions, to carbohydrates as potential therapeutic and diagnostic agents. This book offers a detailed panoramic review of the chemistry and biology of carbohydrates for chemists, biologists and health professionals. Each chapter is authored by contributors expert in the particular area of research. - Explains how carbohydrates are important to life - Details the chemistry, biology and medical aspects of carbohydrates - Interdisciplinary and international team of authors
- Published
- 2008
45. Synthesis, structural characterization, and biological properties of pentyl- and isopentyl-α-D-glucosides.
- Author
-
Charoensapyanan, R., Takahashi, Y., Murakami, S., Ito, K., Rudeekulthamrong, P., and Kaulpiboon, J.
- Subjects
- *
GLUCIDES , *GLUCOSIDES , *GLYCOSYLTRANSFERASES , *BACILLUS circulans , *MALTOSE - Abstract
The study was devoted to the synthesis of pentyl glucosides (PenG) and isopentyl glucosides (Iso-PenG) by transglycosylation using recombinant cyclodextrin glycosyltransferase from Bacillus circulans A11, β-cyclodextrin as a glucosyl donor and 1-pentanol and isopentanol as acceptors. TLC and MS analysis indicated at least 3 products which were in accordance with PenG and IsoPenG having glucose, maltose and maltotriose attached to the alkyl groups of both alcohols. Two products of each glucoside were purified by preparative TLC and their structures were identified by NMR technique to be pentyl-α-D-glucopyranoside (PenG), pentyl-α-D-maltopyranoside (PenG), isopentyl-α-D-glucopyranoside (IsoPenG1) and isopentyl- α-D-maltopyranoside (IsoPenG). The effect of water-in-hexadecane emulsion on emulsion-forming properties showed that PenG had the highest emulsifying activity. Adding PenG to the insoluble Corynebacterium glutamicum amylomaltase from Escherichia coli transformants (A406R), helped to perform it to more soluble conformation. Moreover, it was found that PenG exhibited a higher antibacterial activity against E. coli ATCC 25922 than that of IsoPenG. Hence, the biological properties of the synthesized products may be useful for their applications as emulsifying, solubilizing and antibacterial agents. [ABSTRACT FROM AUTHOR]
- Published
- 2017
- Full Text
- View/download PDF
46. Obesity alters the ovarian glucidic homeostasis disrupting the reproductive outcome of female rats.
- Author
-
Bazzano, María Victoria, Paz, Dante Agustín, and Elia, Evelin Mariel
- Subjects
- *
OBESITY , *GLUCIDES , *HOMEOSTASIS , *DISEASE prevalence , *LABORATORY rats , *OBESITY complications , *ADIPOSE tissues , *ANIMAL experimentation , *HUMAN body composition , *CARRIER proteins , *CELL receptors , *DIET , *GLUCOSE tolerance tests , *INSULIN resistance , *OVARIES , *OXIDOREDUCTASES , *RATS - Abstract
Obesity constitutes a health problem of increasing worldwide prevalence related to many reproductive problems such as infertility, ovulation dysfunction, preterm delivery, fetal growth disorders, etc. The mechanisms linking obesity to these pathologies are not fully understood. Cafeteria diet (CAF) is the animal model used for the study of obesity that more closely reflects western diet habits. Previously we described that CAF induces obesity associated to hyperglycemia, reduced ovarian reserve, presence of follicular cysts and ovulatory impairments. The aim of the present study was to contribute in the understanding of the physiological mechanisms altered as consequence of obesity. For that purpose, female Wistar rats were fed ad libitum with a standard diet (control group) or CAF (Obese group). We found that CAF fed-rats developed obesity, glucose intolerance and insulin resistance. Ovaries from obese rats showed decreased glucose uptake and became insulin resistant, showing decreased ovarian expression of glucotransporter type 4 and insulin receptor gene expression respect to controls. These animals showed an increased follicular nitric oxyde synthase expression that may be responsible for the ovulatory disruptions and for inflammation, a common feature in obesity. Obese rats resulted subfertile and their pups were macrosomic. We conclude that obesity alters the systemic and the ovarian glucidic homeostasis impairing the reproductive outcome. Since macrosomia is a risk factor for metabolic and obstetric disorders in adult life, we suggest that obesity is impacting not only on health and reproduction but it is also impacting on health and reproduction of the offspring. [ABSTRACT FROM AUTHOR]
- Published
- 2017
- Full Text
- View/download PDF
47. Heterocycles From Carbohydrate Precursors
- Author
-
El Sayed H. El Ashry and El Sayed H. El Ashry
- Subjects
- Glucides, Carbohydrates, Heterocyclic compounds--Synthesis
- Abstract
This book is a volume in the series Topics in Heterocyclic Chemistry.Itc- ers the key methods used for designing synthetic approaches to heterocycles from carbohydrates and the value and scope of these methods. Carbohydrates are widely distributed in nature and constitute the largest part of renewable biomasses. Moreover, many carbohydrates and their derivatives are comm- cially available at relatively cheap prices. Consequently their utilization is highly encouraged and economically they are of great signi?cance. Moreover, carbohydrates are highly functionalized compounds that can be readily deri- tized and/or cyclized to provide heterocyclic compounds. This book provides a modern account and an up-to-date description of the advancement in the synthesis of diverse heterocycles from carbohydrates. Carbohydrates can be considered as a source of chiral centers in addition to the variable modi?cation thereof. Herein the elaboration of the carbohydrate molecules for providing different heterocycles is the main objective and team efforts from leaders of the topics has been gathered in this volume. This book is designed to be suitable for students and researchers. It is highly recommended as a reference book and for teaching the fascinating topics related to carbohydrates, heterocycles and organic synthesis. In addition to its importance in academia, it is also an excellent source for information about the variety of methods used in the synthesis of heterocycles important to industry.
- Published
- 2007
48. Advances in Carbohydrate Chemistry and Biochemistry
- Author
-
Derek Horton and Derek Horton
- Subjects
- Carbohydrates, Glucides
- Abstract
Since its inception in 1945, this serial has provided critical and integrating articles written by research specialists that integrate industrial, analytical, and technological aspects of biochemistry, organic chemistry, and instrumentation methodology in the study of carbohydrates. The articles provide a definitive interpretation of the current status and future trends in carbohydrate chemistry and biochemistry.High quality comprehensive reviews covering all aspects of carbohydrate chemistry
- Published
- 2006
49. Dictionary of Carbohydrates with CD-ROM
- Author
-
Peter M. Collins and Peter M. Collins
- Subjects
- Carbohydrates, Carbohydrates--Handbooks, manuals, etc, Glucides
- Abstract
An easy-to-use reference source for all scientists working with carbohydrates, the Dictionary of Carbohydrates with CD-ROM, Second Edition builds on the success of its previous edition by providing a substantially increased number of compounds. The presentation is sharpened by a careful review of existing entries. With 24,000 compounds, it represen
- Published
- 2006
50. The Organic Chemistry of Sugars
- Author
-
Daniel E. Levy, Peter Fügedi, Daniel E. Levy, and Peter Fügedi
- Subjects
- Oligosaccharides, Glycosides, Carbohydrates, Glucosides, Glucides
- Abstract
Intrigued as much by its complex nature as by its outsider status in traditional organic chemistry, the editors of The Organic Chemistry of Sugars compile a groundbreaking resource in carbohydrate chemistry that illustrates the ease at which sugars can be manipulated in a variety of organic reactions. Each chapter contains numerous examples demonst
- Published
- 2006
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