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Your search keyword '"Glassner, Brian J."' showing total 25 results

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25 results on '"Glassner, Brian J."'

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1. Genome-scale functional genomics identify genes preferentially essential for multiple myeloma cells compared to other neoplasias

2. An Embryonic Diapause-like Adaptation with Suppressed Myc Activity Enables Tumor Treatment Persistence

3. Functional Genomics Identify Distinct and Overlapping Genes Mediating Resistance to Different Classes of Heterobifunctional Degraders of Oncoproteins

7. Targeting Mutant KRAS with Novel Mutant-Specific Pharmacological Inhibitors: Activity Against Myeloma and Other Lymphoid Malignant Cells and Molecular Mechanisms of Resistance

9. Detection and frequency estimation of rare variants in pools of genomic DNA from large populations using mutational spectrometry

10. Increasing DNA repair methyltransferase levels via bone barrow stem cell transduction rescues mice from the toxic effects of 1,3-bis(2-chloroethyl)-1-nitrosourea, a chemotherapeutic alkylating agent

11. Combinatorial CRISPR-knockout identifies interactions between key genes and regulatory pathways in myeloma

12. CRISPR studies identify genes preferentially essential for myeloma cells vs. other neoplasias: implications for future therapies selective against MM

13. CRISPR-based functional genomics landscape of genes recurrently mutated in MM

14. Molecular markers of myeloma cell sensitivity vs. resistance to heterobifunctional degraders of oncoproteins: therapeutic implications.

15. Gain-of-function studies with CRISPR-based transcriptional activation at endogenous genomic loci reveals genes with critical roles for myeloma cells

16. Abstract LB-118: Characterization of lineage vs. context-dependent essential genes in multiple myeloma using CRISPR-Cas9 genome editing

17. Molecular basis for discriminating between normal and damaged bases by the human alkyladenine glycosylase, AAG

23. DNA repair methyltransferase (Mgmt) knockout mice are sensitive to the lethal effects of chemotherapeutic alkylating agents.

24. Specific negative effects resulting from elevated levels of the recombinational repair protein Rad54p in <TOGGLE>Saccharomyces cerevisiae</TOGGLE>

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