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1. Demographic and mental health assessments in the adolescent brain and cognitive development study: Updates and age-related trajectories

Author

Barch, Deanna M, Albaugh, Matthew D, Baskin-Sommers, Arielle, Bryant, Brittany E, Clark, Duncan B, Dick, Anthony Steven, Feczko, Eric, Foxe, John J, Gee, Dylan G, Giedd, Jay, Glantz, Meyer D, Hudziak, James J, Karcher, Nicole R, LeBlanc, Kimberly, Maddox, Melanie, McGlade, Erin C, Mulford, Carrie, Nagel, Bonnie J, Neigh, Gretchen, Palmer, Clare E, Potter, Alexandra S, Sher, Kenneth J, Tapert, Susan F, Thompson, Wesley K, and Xie, Laili

Subjects
Biological Psychology, Clinical and Health Psychology, Psychology, Mental Illness, Brain Disorders, Pediatric, Basic Behavioral and Social Science, Health Disparities, Social Determinants of Health, Neurosciences, Mental Health, Behavioral and Social Science, 2.3 Psychological, social and economic factors, Mental health, Good Health and Well Being, Adolescent, Brain, Child, Cognition, Female, Humans, Longitudinal Studies, Male, Psychopathology, Residence Characteristics, Assessment, Longitudinal assessment, Clinical Sciences, Cognitive Sciences, Biological psychology, Clinical and health psychology
Abstract

The Adolescent Brain Cognitive Development (ABCD) Study of 11,880 youth incorporates a comprehensive range of measures assessing predictors and outcomes related to mental health across childhood and adolescence in participating youth, as well as information about family mental health history. We have previously described the logic and content of the mental health assessment battery at Baseline and 1-year follow-up. Here, we describe changes to that battery and issues and clarifications that have emerged, as well as additions to the mental health battery at the 2-, 3-, 4-, and 5-year follow-ups. We capitalize on the recent release of longitudinal data for caregiver and youth report of mental health data to evaluate trajectories of dimensions of psychopathology as a function of demographic factors. For both caregiver and self-reported mental health symptoms, males showed age-related decreases in internalizing and externalizing symptoms, while females showed an increase in internalizing symptoms with age. Multiple indicators of socioeconomic status (caregiver education, family income, financial adversity, neighborhood poverty) accounted for unique variance in both caregiver and youth-reported externalizing and internalizing symptoms. These data highlight the importance of examining developmental trajectories of mental health as a function of key factors such as sex and socioeconomic environment.

Published
2021

3. Optimizing scalable, technology-supported behavioral interventions to prevent opioid misuse among adolescents and young adults in the emergency department: A randomized controlled trial protocol

Author

Bonar, Erin E, Kidwell, Kelley M, Bohnert, Amy SB, Bourque, Carrie A, Carter, Patrick M, Clark, Sarah J, Glantz, Meyer D, King, Cheryl A, Losman, Eve D, McCabe, Sean Esteban, Philyaw-Kotov, Meredith L, Prosser, Lisa A, Voepel-Lewis, Terri, Zheng, Kai, and Walton, Maureen A

Subjects
Health Services and Systems, Biomedical and Clinical Sciences, Public Health, Health Sciences, Comparative Effectiveness Research, Drug Abuse (NIDA only), Pediatric, Clinical Trials and Supportive Activities, Substance Abuse Prevention, Clinical Research, Behavioral and Social Science, Prescription Drug Abuse, Prevention, Health Services, Substance Misuse, 3.1 Primary prevention interventions to modify behaviours or promote wellbeing, Prevention of disease and conditions, and promotion of well-being, Mental health, Good Health and Well Being, Adolescent, Adult, Analgesics, Opioid, Drug Overdose, Emergency Service, Hospital, Humans, Opioid-Related Disorders, Randomized Controlled Trials as Topic, Technology, Young Adult, Opioids, Adolescents, Emerging adults, Intervention, Medical and Health Sciences, General Clinical Medicine, Biomedical and clinical sciences, Health sciences
Abstract

Preventing opioid misuse and opioid use disorder is critical among at-risk adolescents and young adults (AYAs). An Emergency Department (ED) visit provides an opportunity for delivering interventions during a rapidly changing opioid landscape. This paper describes pilot data and the protocol for a 2 × 2 factorial randomized controlled trial testing efficacy of early interventions to reduce escalation of opioid (prescription or illicit) misuse among at-risk AYAs. Interventions are delivered using technology by health coaches. AYAs ages 16-30 in the ED screening positive for prescription opioid use (+ ≥ 1 risk factor) or opioid misuse will be stratified by risk severity, sex, and age group. Participants will be randomly assigned to a condition at intake, either a live video health coach-delivered single session or a control condition of an enhanced usual care (EUC) community resource brochure. They are also randomly assigned to one of two post-intake conditions: health coach-delivered portal-like messaging via web portal over 30 days or EUC delivered at 30 days post-intake. Thus, the trial has four groups: health coach-delivered session+portal, health coach-delivered session+EUC, EUC + portal, and EUC + EUC. Outcomes will be measured at 3-, 6-, and 12-months. The primary outcome is opioid misuse based on a modified Alcohol Smoking and Substance Involvement Screening Test. Secondary outcomes include other opioid outcomes (e.g., days of opioid misuse, overdose risk behaviors), other substance misuse and consequences, and impaired driving. This study is innovative by testing the efficacy of feasible and scalable technology-enabled interventions to reduce and prevent opioid misuse and opioid use disorder. Trial Registration:ClinicalTrials.gov University of Michigan HUM00177625 NCT Registration: NCT04550715.

Published
2021

4. Image processing and analysis methods for the Adolescent Brain Cognitive Development Study

Author

Hagler, Donald J, Hatton, SeanN, Cornejo, M Daniela, Makowski, Carolina, Fair, Damien A, Dick, Anthony Steven, Sutherland, Matthew T, Casey, BJ, Barch, Deanna M, Harms, Michael P, Watts, Richard, Bjork, James M, Garavan, Hugh P, Hilmer, Laura, Pung, Christopher J, Sicat, Chelsea S, Kuperman, Joshua, Bartsch, Hauke, Xue, Feng, Heitzeg, Mary M, Laird, Angela R, Trinh, Thanh T, Gonzalez, Raul, Tapert, Susan F, Riedel, Michael C, Squeglia, Lindsay M, Hyde, Luke W, Rosenberg, Monica D, Earl, Eric A, Howlett, Katia D, Baker, Fiona C, Soules, Mary, Diaz, Jazmin, de Leon, Octavio Ruiz, Thompson, Wesley K, Neale, Michael C, Herting, Megan, Sowell, Elizabeth R, Alvarez, Ruben P, Hawes, Samuel W, Sanchez, Mariana, Bodurka, Jerzy, Breslin, Florence J, Morris, Amanda Sheffield, Paulus, Martin P, Simmons, W Kyle, Polimeni, Jonathan R, van der Kouwe, Andre, Nencka, Andrew S, Gray, Kevin M, Pierpaoli, Carlo, Matochik, John A, Noronha, Antonio, Aklin, Will M, Conway, Kevin, Glantz, Meyer, Hoffman, Elizabeth, Little, Roger, Lopez, Marsha, Pariyadath, Vani, Weiss, Susan RB, Wolff-Hughes, Dana L, DelCarmen-Wiggins, Rebecca, Ewing, Sarah W Feldstein, Miranda-Dominguez, Oscar, Nagel, Bonnie J, Perrone, Anders J, Sturgeon, Darrick T, Goldstone, Aimee, Pfefferbaum, Adolf, Pohl, Kilian M, Prouty, Devin, Uban, Kristina, Bookheimer, Susan Y, Dapretto, Mirella, Galvan, Adriana, Bagot, Kara, Giedd, Jay, Infante, M Alejandra, Jacobus, Joanna, Patrick, Kevin, Shilling, Paul D, Desikan, Rahul, Li, Yi, Sugrue, Leo, Banich, Marie T, Friedman, Naomi, Hewitt, John K, Hopfer, Christian, Sakai, Joseph, Tanabe, Jody, Cottler, Linda B, Nixon, Sara Jo, Chang, Linda, Cloak, Christine, Ernst, Thomas, Reeves, Gloria, Kennedy, David N, Heeringa, Steve, and Peltier, Scott

Subjects
Biomedical and Clinical Sciences, Health Sciences, Brain Disorders, Mental Illness, Mental Health, Clinical Research, Pediatric, Drug Abuse (NIDA only), Biomedical Imaging, Basic Behavioral and Social Science, Substance Misuse, Neurosciences, Women's Health, Behavioral and Social Science, Mental health, Neurological, Good Health and Well Being, Adolescent, Adolescent Development, Brain, Brain Mapping, Diffusion Magnetic Resonance Imaging, Humans, Image Processing, Computer-Assisted, Magnetic Resonance Imaging, Multimodal Imaging, Signal Processing, Computer-Assisted, Magnetic resonance imaging, ABCD, Data sharing, Processing pipeline, Medical and Health Sciences, Psychology and Cognitive Sciences, Neurology & Neurosurgery, Biomedical and clinical sciences, Health sciences
Abstract

The Adolescent Brain Cognitive Development (ABCD) Study is an ongoing, nationwide study of the effects of environmental influences on behavioral and brain development in adolescents. The main objective of the study is to recruit and assess over eleven thousand 9-10-year-olds and follow them over the course of 10 years to characterize normative brain and cognitive development, the many factors that influence brain development, and the effects of those factors on mental health and other outcomes. The study employs state-of-the-art multimodal brain imaging, cognitive and clinical assessments, bioassays, and careful assessment of substance use, environment, psychopathological symptoms, and social functioning. The data is a resource of unprecedented scale and depth for studying typical and atypical development. The aim of this manuscript is to describe the baseline neuroimaging processing and subject-level analysis methods used by ABCD. Processing and analyses include modality-specific corrections for distortions and motion, brain segmentation and cortical surface reconstruction derived from structural magnetic resonance imaging (sMRI), analysis of brain microstructure using diffusion MRI (dMRI), task-related analysis of functional MRI (fMRI), and functional connectivity analysis of resting-state fMRI. This manuscript serves as a methodological reference for users of publicly shared neuroimaging data from the ABCD Study.

Published
2019

5. Demographic, physical and mental health assessments in the adolescent brain and cognitive development study: Rationale and description

Author

Barch, Deanna M, Albaugh, Matthew D, Avenevoli, Shelli, Chang, Linda, Clark, Duncan B, Glantz, Meyer D, Hudziak, James J, Jernigan, Terry L, Tapert, Susan F, Yurgelun-Todd, Debbie, Alia-Klein, Nelly, Potter, Alexandra S, Paulus, Martin P, Prouty, Devin, Zucker, Robert A, and Sher, Kenneth J

Subjects
Biological Psychology, Psychology, Drug Abuse (NIDA only), Basic Behavioral and Social Science, Pediatric, Neurosciences, Prevention, Mental Health, Substance Misuse, Brain Disorders, Pediatric Research Initiative, Clinical Research, Behavioral and Social Science, Mental health, Good Health and Well Being, Adolescent, Brain, Child, Cognition, Demography, Female, Humans, Male, Psychopathology, Assessment, Physical health, Clinical Sciences, Cognitive Sciences, Biological psychology, Clinical and health psychology
Abstract

The Adolescent Brain and Cognitive Development (ABCD) Study incorporates a comprehensive range of measures assessing predictors and outcomes related to both mental and physical health across childhood and adolescence. The workgroup developed a battery that would assess a comprehensive range of domains that address study aims while minimizing participant and family burden. We review the major considerations that went into deciding what constructs to cover in the demographics, physical health and mental health domains, as well as the process of selecting measures, piloting and refining the originally proposed battery. We present a description of the baseline battery, as well as the six-month interim assessments and the one-year follow-up assessments. This battery includes assessments from the perspectives of both the parent and the target youth, as well as teacher reports. This battery will provide a foundational baseline assessment of the youth's current function so as to permit characterization of stability and change in key domains over time. The findings from this battery will also be utilized to identify both resilience markers that predict healthy development and risk factors for later adverse outcomes in physical health, mental health, and substance use and abuse.

Published
2018

6. Demographic and mental health assessments in the adolescent brain and cognitive development study: Updates and age-related trajectories

Author

Barch, Deanna M., Albaugh, Matthew D., Baskin-Sommers, Arielle, Bryant, Brittany E., Clark, Duncan B., Dick, Anthony Steven, Feczko, Eric, Foxe, John J., Gee, Dylan G., Giedd, Jay, Glantz, Meyer D., Hudziak, James J., Karcher, Nicole R., LeBlanc, Kimberly, Maddox, Melanie, McGlade, Erin C., Mulford, Carrie, Nagel, Bonnie J., Neigh, Gretchen, Palmer, Clare E., Potter, Alexandra S., Sher, Kenneth J., Tapert, Susan F., Thompson, Wesley K., and Xie, Laili

Published
2021
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7. Optimizing scalable, technology-supported behavioral interventions to prevent opioid misuse among adolescents and young adults in the emergency department: A randomized controlled trial protocol

Author

Bonar, Erin E., Kidwell, Kelley M., Bohnert, Amy S.B., Bourque, Carrie A., Carter, Patrick M., Clark, Sarah J., Glantz, Meyer D., King, Cheryl A., Losman, Eve D., McCabe, Sean Esteban, Philyaw-Kotov, Meredith L., Prosser, Lisa A., Voepel-Lewis, Terri, Zheng, Kai, and Walton, Maureen A.

Published
2021
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8. The epidemiology of alcohol use disorders cross-nationally: Findings from the World Mental Health Surveys

Author

Glantz, Meyer D., Bharat, Chrianna, Degenhardt, Louisa, Sampson, Nancy A., Scott, Kate M., Lim, Carmen C.W., Al-Hamzawi, Ali, Alonso, Jordi, Andrade, Laura Helena, Cardoso, Graca, De Girolamo, Giovanni, Gureje, Oye, He, Yanling, Hinkov, Hristo, Karam, Elie G., Karam, Georges, Kovess-Masfety, Viviane, Lasebikan, Victor, Lee, Sing, Levinson, Daphna, McGrath, John, Medina-Mora, Maria-Elena, Mihaescu-Pintia, Constanta, Mneimneh, Zeina, Moskalewicz, Jacek, Navarro-Mateu, Fernando, Posada-Villa, José, Rapsey, Charlene, Stagnaro, Juan Carlos, Tachimori, Hisateru, Ten Have, Margreet, Tintle, Nathan, Torres, Yolanda, Williams, David R., Ziv, Yuval, and Kessler, Ronald C.

Published
2020
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9. Image processing and analysis methods for the Adolescent Brain Cognitive Development Study

Author

Hagler, Donald J., Jr., Hatton, SeanN., Cornejo, M. Daniela, Makowski, Carolina, Fair, Damien A., Dick, Anthony Steven, Sutherland, Matthew T., Casey, B.J., Barch, Deanna M., Harms, Michael P., Watts, Richard, Bjork, James M., Garavan, Hugh P., Hilmer, Laura, Pung, Christopher J., Sicat, Chelsea S., Kuperman, Joshua, Bartsch, Hauke, Xue, Feng, Heitzeg, Mary M., Laird, Angela R., Trinh, Thanh T., Gonzalez, Raul, Tapert, Susan F., Riedel, Michael C., Squeglia, Lindsay M., Hyde, Luke W., Rosenberg, Monica D., Earl, Eric A., Howlett, Katia D., Baker, Fiona C., Soules, Mary, Diaz, Jazmin, de Leon, Octavio Ruiz, Thompson, Wesley K., Neale, Michael C., Herting, Megan, Sowell, Elizabeth R., Alvarez, Ruben P., Hawes, Samuel W., Sanchez, Mariana, Bodurka, Jerzy, Breslin, Florence J., Morris, Amanda Sheffield, Paulus, Martin P., Simmons, W. Kyle, Polimeni, Jonathan R., van der Kouwe, Andre, Nencka, Andrew S., Gray, Kevin M., Pierpaoli, Carlo, Matochik, John A., Noronha, Antonio, Aklin, Will M., Conway, Kevin, Glantz, Meyer, Hoffman, Elizabeth, Little, Roger, Lopez, Marsha, Pariyadath, Vani, Weiss, Susan RB., Wolff-Hughes, Dana L., DelCarmen-Wiggins, Rebecca, Feldstein Ewing, Sarah W., Miranda-Dominguez, Oscar, Nagel, Bonnie J., Perrone, Anders J., Sturgeon, Darrick T., Goldstone, Aimee, Pfefferbaum, Adolf, Pohl, Kilian M., Prouty, Devin, Uban, Kristina, Bookheimer, Susan Y., Dapretto, Mirella, Galvan, Adriana, Bagot, Kara, Giedd, Jay, Infante, M. Alejandra, Jacobus, Joanna, Patrick, Kevin, Shilling, Paul D., Desikan, Rahul, Li, Yi, Sugrue, Leo, Banich, Marie T., Friedman, Naomi, Hewitt, John K., Hopfer, Christian, Sakai, Joseph, Tanabe, Jody, Cottler, Linda B., Nixon, Sara Jo, Chang, Linda, Cloak, Christine, Ernst, Thomas, Reeves, Gloria, Kennedy, David N., Heeringa, Steve, Peltier, Scott, Schulenberg, John, Sripada, Chandra, Zucker, Robert A., Iacono, William G., Luciana, Monica, Calabro, Finnegan J., Clark, Duncan B., Lewis, David A., Luna, Beatriz, Schirda, Claudiu, Brima, Tufikameni, Foxe, John J., Freedman, Edward G., Mruzek, Daniel W., Mason, Michael J., Huber, Rebekah, McGlade, Erin, Prescot, Andrew, Renshaw, Perry F., Yurgelun-Todd, Deborah A., Allgaier, Nicholas A., Dumas, Julie A., Ivanova, Masha, Potter, Alexandra, Florsheim, Paul, Larson, Christine, Lisdahl, Krista, Charness, Michael E., Fuemmeler, Bernard, Hettema, John M., Maes, Hermine H., Steinberg, Joel, Anokhin, Andrey P., Glaser, Paul, Heath, Andrew C., Madden, Pamela A., Baskin-Sommers, Arielle, Constable, R. Todd, Grant, Steven J., Dowling, Gayathri J., Brown, Sandra A., Jernigan, Terry L., and Dale, Anders M.

Published
2019
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10. The epidemiology of drug use disorders cross-nationally: Findings from the WHO’s World Mental Health Surveys

Author

Degenhardt, Louisa, Bharat, Chrianna, Glantz, Meyer D., Sampson, Nancy A., Scott, Kate, Lim, Carmen C.W., Aguilar-Gaxiola, Sergio, Al-Hamzawi, Ali, Alonso, Jordi, Andrade, Laura H., Bromet, Evelyn J., Bruffaerts, Ronny, Bunting, Brendan, de Girolamo, Giovanni, Gureje, Oye, Haro, Josep Maria, Harris, Meredith G., He, Yanling, de Jonge, Peter, Karam, Elie G., Karam, Georges E., Kiejna, Andrzej, Lee, Sing, Lepine, Jean-Pierre, Levinson, Daphna, Makanjuola, Victor, Medina-Mora, Maria Elena, Mneimneh, Zeina, Navarro-Mateu, Fernando, Posada-Villa, José, Stein, Dan J., Tachimori, Hisateru, Torres, Yolanda, Zarkov, Zahari, Chatterji, Somnath, and Kessler, Ronald C.

Published
2019
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12. Development and evaluation of a risk algorithm predicting alcohol dependence after early onset of regular alcohol use

Author

Bharat, Chrianna, primary, Glantz, Meyer D., additional, Aguilar‐Gaxiola, Sergio, additional, Alonso, Jordi, additional, Bruffaerts, Ronny, additional, Bunting, Brendan, additional, Caldas‐de‐Almeida, José Miguel, additional, Cardoso, Graça, additional, Chardoul, Stephanie, additional, de Jonge, Peter, additional, Gureje, Oye, additional, Haro, Josep Maria, additional, Harris, Meredith G., additional, Karam, Elie G., additional, Kawakami, Norito, additional, Kiejna, Andrzej, additional, Kovess‐Masfety, Viviane, additional, Lee, Sing, additional, McGrath, John J., additional, Moskalewicz, Jacek, additional, Navarro‐Mateu, Fernando, additional, Rapsey, Charlene, additional, Sampson, Nancy A., additional, Scott, Kate M., additional, Tachimori, Hisateru, additional, ten Have, Margreet, additional, Vilagut, Gemma, additional, Wojtyniak, Bogdan, additional, Xavier, Miguel, additional, Kessler, Ronald C., additional, and Degenhardt, Louisa, additional

Published
2023
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13. The descriptive epidemiology of DSM-IV Adult ADHD in the World Health Organization World Mental Health Surveys

Author

Fayyad, John, Sampson, Nancy A., Hwang, Irving, Adamowski, Tomasz, Aguilar-Gaxiola, Sergio, Al-Hamzawi, Ali, Andrade, Laura H. S. G., Borges, Guilherme, de Girolamo, Giovanni, Florescu, Silvia, Gureje, Oye, Haro, Josep Maria, Hu, Chiyi, Karam, Elie G., Lee, Sing, Navarro-Mateu, Fernando, O’Neill, Siobhan, Pennell, Beth-Ellen, Piazza, Marina, Posada-Villa, José, ten Have, Margreet, Torres, Yolanda, Xavier, Miguel, Zaslavsky, Alan M., Kessler, Ronald C., Adamowski, Tomasz, Aguilar-Gaxiola, Sergio, Al-Hamzawi, Ali, Al-Kaisy, Mohammad, Subaie, Abdullah Al, Alonso, Jordi, Altwaijri, Yasmin, Andrade, Laura Helena, Atwoli, Lukoye, Auerbach, Randy P., Axinn, William G., Benjet, Corina, Borges, Guilherme, Bossarte, Robert M., Bromet, Evelyn J., Bruffaerts, Ronny, Bunting, Brendan, Caffo, Ernesto, de Almeida, Jose Miguel Caldas, Cardoso, Graca, Cia, Alfredo H., Chardoul, Stephanie, Chatterji, Somnath, Filho, Alexandre Chiavegatto, Cuijpers, Pim, Degenhardt, Louisa, de Girolamo, Giovanni, de Graaf, Ron, de Jonge, Peter, Demyttenaere, Koen, Ebert, David D., Evans-Lacko, Sara, Fayyad, John, Fiestas, Fabian, Florescu, Silvia, Forresi, Barbara, Galea, Sandro, Germine, Laura, Gilman, Stephen E., Ghimire, Dirgha J., Glantz, Meyer D., Gureje, Oye, Haro, Josep Maria, He, Yanling, Hinkov, Hristo, Hu, Chi-yi, Huang, Yueqin, Karam, Aimee Nasser, Karam, Elie G., Kawakami, Norito, Kessler, Ronald C., Kiejna, Andrzej, Koenen, Karestan C., Kovess-Masfety, Viviane, Lago, Luise, Lara, Carmen, Lee, Sing, Lepine, Jean-Pierre, Levav, Itzhak, Levinson, Daphna, Liu, Zhaorui, Martins, Silvia S., Matschinger, Herbert, McGrath, John J., McLaughlin, Katie A., Medina-Mora, Maria Elena, Mneimneh, Zeina, Moskalewicz, Jacek, Murphy, Samuel D., Navarro-Mateu, Fernando, Nock, Matthew K., O’Neill, Siobhan, Oakley-Browne, Mark, Hans Ormel, J., Pennell, Beth-Ellen, Piazza, Marina, Pinder-Amaker, Stephanie, Piotrowski, Patryk, Posada-Villa, Jose, Ruscio, Ayelet M., Scott, Kate M., Shahly, Vicki, Silove, Derrick, Slade, Tim, Smoller, Jordan W., Stagnaro, Juan Carlos, Stein, Dan J., Street, Amy E., Tachimori, Hisateru, Taib, Nezar, Have, Margreet ten, Thornicroft, Graham, Torres, Yolanda, Viana, Maria Carmen, Vilagut, Gemma, Wells, Elisabeth, Williams, David R., Williams, Michelle A., Wojtyniak, Bogdan, Zaslavsky, Alan M., and on behalf of the WHO World Mental Health Survey Collaborators

Published
2017
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16. The associations between traumatic experiences and subsequent onset of a substance use disorder: Findings from the World Health Organization World Mental Health surveys

Author

Degenhardt, Louisa, primary, Bharat, Chrianna, additional, Glantz, Meyer D., additional, Bromet, Evelyn J., additional, Alonso, Jordi, additional, Bruffaerts, Ronny, additional, Bunting, Brendan, additional, de Girolamo, Giovanni, additional, de Jonge, Peter, additional, Florescu, Silvia, additional, Gureje, Oye, additional, Haro, Josep Maria, additional, Harris, Meredith G., additional, Hinkov, Hristo, additional, Karam, Elie G., additional, Karam, Georges, additional, Kovess-Masfety, Viviane, additional, Lee, Sing, additional, Makanjuola, Victor, additional, Medina-Mora, Maria Elena, additional, Navarro-Mateu, Fernando, additional, Piazza, Marina, additional, Posada-Villa, José, additional, Scott, Kate M., additional, Stein, Dan J., additional, Tachimori, Hisateru, additional, Tintle, Nathan, additional, Torres, Yolanda, additional, Viana, Maria Carmen, additional, Kessler, Ronald C., additional, Aguilar-Gaxiola, Sergio, additional, Al-Hamzawi, Ali, additional, Al-Kaisy, Mohammed Salih, additional, Altwaijri, Yasmin, additional, Helena Andrade, Laura, additional, Atwoli, Lukoye, additional, Benjet, Corina, additional, Borges, Guilherme, additional, Caldas-de-Almeida, Jose Miguel, additional, Cardoso, Graça, additional, Chatterji, Somnath, additional, Cia, Alfredo H., additional, Degenhardt, Louisa, additional, Demyttenaere, Koen, additional, Girolamo, Giovanni de, additional, Hu, Chi-yi, additional, Karam, Aimee Nasser, additional, Kawakami, Norito, additional, Kiejna, Andrzej, additional, Lepine, Jean-Pierre, additional, McGrath, John, additional, Mneimneh, Zeina, additional, Moskalewicz, Jacek, additional, Posada-Villa, Jose, additional, Slade, Tim, additional, Stagnaro, Juan Carlos, additional, ten Have, Margreet, additional, Vigo, Daniel V., additional, Whiteford, Harvey, additional, Williams, David R., additional, and Wojtyniak, Bogdan, additional

Published
2022
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19. 028 Injury-related risk behaviors among adolescents and young adults in the emergency department enrolled in an opioid prevention randomized controlled trial

Author

Seewald, Laura, primary, Blow, Fred, additional, Carter, Patrick, additional, Glantz, Meyer, additional, Kidwell, Kelley, additional, King, Cheryl, additional, Losman, Eve, additional, Esteban, Sean, additional, Voepel-Lewis, Terri, additional, Zheng, Kai, additional, Bonar, Erin, additional, and Walton, Maureen, additional

Published
2022
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20. Drugs and the Elderly Adult. Research Issues 32.

Author

Metrotec Research Associates, Washington, DC. and Glantz, Meyer D.

Abstract

This book, on the nature and problems of inappropriate drug use by older adults, provides researchers and health practitioners with an up-to-date survey and overview of the literature on drug use, misuse, and abuse among the elderly. The volume provides abstracts of 100 selected scientific articles on the major topic areas in the field. The bibliography represents a fairly comprehensive listing of the United States literature with some relevant foreign materials. The abstracted publications, primarily scientific journal articles, are divided into eight sections preceded by a summary of the topic area presented in that section. The summaries highlight the research and related literature on that topic. The eight topics are: (1) an overview of drugs and the elderly; (2) epidemiology of drug use; (3) illegal drug use, older addicts, and the maturing-out hypothesis; (4) misuse of legal drugs; (5) pharmacology and therapeutics; (6) alcohol use and abuse; (7) consequences of drug use, misuse and abuse; and (8) prevention and treatment programs. (Author/JAC)

Published
1983

22. Special Issue: Demographic and Mental Health Assessments in the Adolescent Brain and Cognitive Development Study: Updates and Longitudinal Trajectories

Author

Barch, Deanna M., primary, Albaugh, Matthew D., additional, Baskin-Sommers, Arielle, additional, Bryant, Brittany E., additional, Clark, Duncan B., additional, Dick, Anthony Steven, additional, Feczko, Eric, additional, Foxe, John J., additional, Gee, Dylan G., additional, Giedd, Jay, additional, Glantz, Meyer D., additional, Hudziak, James J., additional, Karcher, Nicole R., additional, LeBlanc, Kimberly, additional, Maddox, Melanie, additional, McGlade, Erin C., additional, Mulford, Carrie, additional, Nagel, Bonnie J., additional, Neigh, Gretchen, additional, Palmer, Clare E, additional, Potter, Alexandra S., additional, Sher, Kenneth J., additional, Tapert, Susan F., additional, Thompson, Wesley K., additional, and Xie, Laili, additional

Published
2021
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24. Corrigendum to “The epidemiology of alcohol use disorders cross-nationally: Findings from the World Mental Health Surveys” [Addict. Behav. 102 (2020) 106128]

Author

Glantz, Meyer D., Bharat, Chrianna, Degenhardt, Louisa, Sampson, Nancy A., Scott, Kate M., Lim, Carmen C.W., Al-Hamzawi, Ali, Alonso, Jordi, Andrade, Laura Helena, Cardoso, Graca, De Girolamo, Giovanni, Gureje, Oye, He, Yanling, Hinkov, Hristo, Karam, Elie G., Karam, Georges, Kovess-Masfety, Viviane, Lasebikan, Victor, Lee, Sing, Levinson, Daphna, McGrath, John, Medina-Mora, Maria-Elena, Mihaescu-Pintia, Constanta, Mneimneh, Zeina, Moskalewicz, Jacek, Navarro-Mateu, Fernando, Posada-Villa, José, Rapsey, Charlene, Stagnaro, Juan Carlos, Tachimori, Hisateru, Have, Margreet Ten, Tintle, Nathan, Torres, Yolanda, Williams, David R., Ziv, Yuval, and Kessler, Ronald C.

Published
2020
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25. Alcohol Abuse in Developed and Developing Countries in the World Mental Health Surveys: Socially Defined Consequences or Psychiatric Disorder?

Author

Glantz, Meyer D., Medina-Mora, Maria Elena, Petukhova, Maria, Andrade, Laura Helena, Anthony, James C., de Girolamo, Giovanni, de Graaf, Ron, Degenhardt, Louisa, Demyttenaere, Koen, Florescu, Silvia, Gureje, Oye, Haro, Josep Maria, Horiguchi, Itsuko, Karam, Elie G., Kostyuchenko, Stanislav, Lee, Sing, Lépine, Jean-Pierre, Matschinger, Herbert, Neumark, Yehuda, Posada-Villa, Jose, Sagar, Rajesh, Stein, Dan J., Tomov, Toma, Wells, Elisabeth J., Chatterji, Somnath, and Kessler, Ronald C.

Published
2014
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27. List of Contributors

Author

Adams, Jeremy, primary, Aivadyan, Christina, additional, Andrade, Jackie, additional, Andreassen, Cecilie Schou, additional, Attwood, Angela, additional, Aveyard, Paul, additional, Baker, Amanda, additional, Balsam, Kimberly F., additional, Bancroft, John, additional, Barth, Kelly S., additional, Bauld, Linda, additional, Beranuy, Marta, additional, Blume, Arthur W., additional, Bolton, James M., additional, Bonn-Miller, Marcel O., additional, Borsari, Brian, additional, Brady, Kathleen T., additional, Braun, Ashley R., additional, Britton, John, additional, Brown, Brian P., additional, Campbell, Justine, additional, Carbonell, Xavier, additional, Carvalho, Félix, additional, Caselli, Gabriele, additional, Castellanos-Ryan, Natalie, additional, Chan, Grace, additional, Chartier, Karen Grube, additional, Chen, Chuan-Yu, additional, Chen, Wei J., additional, Chung, Tammy, additional, Clemens, Kelly J., additional, Collado-Rodriguez, Anahi, additional, Conrad, Megan, additional, Conrod, Patricia J., additional, Copeland, Jan, additional, Correia, Christopher J., additional, Craft, Baine B., additional, Crosland, Ann, additional, Cunha-Oliveira, Teresa, additional, Davis, Kelly C., additional, Deady, Mark, additional, Degenhardt, Louisa, additional, Delfabbro, Paul H., additional, Dennhardt, Ashley A., additional, Dillon, Paul, additional, Drobes, David J., additional, Eaddy, Jessica L., additional, Echeburúa, Enrique, additional, Faden, Vivian B., additional, Fenton, Miriam C., additional, Ferguson, Stuart G., additional, Fernandez-Serrano, M.J., additional, Field, Matt, additional, Fossos, Nicole, additional, Foster, Dawn W., additional, Franken, Ingmar H.A., additional, Geisner, Irene M., additional, George, William H., additional, Ghandour, Lilian A., additional, Gil-Rivas, Virginia, additional, Gilmore, Amanda K., additional, Glantz, Meyer D., additional, Gold, Mark S., additional, Gonzalez, Vivian M., additional, Griffiths, Mark D., additional, Grov, Christian, additional, Grover, Kristin W., additional, Haighton, Catherine A., additional, Hajek, Peter, additional, Hall, Wayne, additional, Hanson, David J., additional, Harrell, Paul, additional, Hasin, Deborah, additional, Hasking, Penelope Anne, additional, Hastings, Gerard, additional, Heaton, Jennifer A., additional, Heinz, Adrienne J., additional, Hendricks, Shai, additional, Hermens, Daniel, additional, Hesselbrock, Michie N., additional, Hesselbrock, Victor M., additional, Hill, Elizabeth M., additional, Hingson, Ralph W., additional, Hogan, Julianna, additional, Horvath, Keith J., additional, Hsu, Sharon Hsin, additional, Huang, Xiuqin, additional, Hunter-Reel, Dorian, additional, Jiang, Qiaolei, additional, Johnson, Thomas J., additional, Kanayama, Gen, additional, Kaner, Eileen F.S., additional, Kassel, Jon D., additional, Kay-Lambkin, Frances, additional, Kaye, Sharlene S., additional, Kaysen, Debra, additional, Kemps, Eva, additional, Kilmer, Jason R., additional, King, Daniel L., additional, Klein, Axel, additional, Kosiba, Jesse, additional, Kristeller, Jean L., additional, Lee, Grace P., additional, Lehavot, Keren, additional, Lejoyeux, Michel, additional, Lejuez, Carl, additional, Leonard, Kenneth E., additional, Lewis, Melissa A., additional, Lindgren, Kristen P., additional, Ling, Jonathan, additional, Litt, Dana, additional, Littlefield, Andrew K., additional, Lustyk, M. Kathleen B., additional, MacPherson, Laura, additional, MacQueen, David A., additional, Maggs, Jennifer L., additional, Malcolm, Robert, additional, Marel, Christina, additional, Marlatt, G. Alan, additional, Martens, Matthew P., additional, Martins, Silvia S., additional, May, Jon, additional, Maziak, Wasim, additional, McKetin, Rebecca, additional, McNeill, Ann, additional, McWhorter, Linda, additional, Mills, Katherine L., additional, Mishra, Manish K., additional, Molina, Yamile, additional, Moselhy, Hamdy Fouad, additional, Mueser, Kim T., additional, Munafò, Marcus, additional, Murphy, James G., additional, Murray, Rachael, additional, Neighbors, Clayton, additional, Noel, Nora E., additional, Nolen-Hoeksema, Susan, additional, Noordsy, Douglas L., additional, O'Farrell, Timothy J., additional, Oberst, Ursula, additional, Odenwald, Michael, additional, Oliveira, Catarina R., additional, Oliver, Jason A., additional, Oei, Tian P.S., additional, Parsons, Jeffrey T., additional, Patrick, Megan E., additional, Paulus, Martin P., additional, Pope, Harrison G., additional, Powell, Patricia A., additional, Proctor, Dawn, additional, Quigley, Brian M., additional, Ramo, Danielle E., additional, Rego, Ana Cristina, additional, Rehm, Jürgen, additional, Reynolds, Elizabeth K., additional, Robinson, Jennifer A., additional, Rodriguez, Lindsey, additional, Roll, John M., additional, Rose, Abigail K., additional, Rosenberg, Harold, additional, Rudisill, Desiree M., additional, Samokhvalov, Andriy V., additional, Sanchez, Zila M., additional, Santoya, Natalia, additional, Schacht, Rebecca L., additional, Schraufnagel, Trevor J., additional, Schulenberg, John E., additional, Schumm, Jeremiah A., additional, Shahab, Lion, additional, Shiffman, Saul, additional, Shriner, Richard L., additional, Sinha, Rajita, additional, Skewes, Monica C., additional, Smith, Andrew Paul, additional, Smith, Karen E., additional, Spada, Marcantonio, additional, Stacy, Alan W., additional, Steckler, Gillian, additional, Stewart, Jennifer L., additional, Storr, Carla L., additional, Strodl, Esben, additional, Oei, Tian Po Sumantri, additional, Tao, Ran, additional, Teesson, Maree, additional, Thakker, Jo, additional, Tidwell, Judy, additional, Tiggemann, Marika, additional, Tirapu-Ustarroz, J., additional, Toneatto, Tony, additional, Veatch, Lynn M., additional, Veilleux, Jennifer C., additional, Verdejo-García, A., additional, Warfa, Nasir, additional, Weinstein, Aviv, additional, West, Robert, additional, Westermeyer, Joseph, additional, White, Aaron M., additional, Wiers, Reinout W., additional, Wilson, Graeme B., additional, Winograd, Rachel P., additional, Winstock, Adam R., additional, Witkiewitz, Katie, additional, Woody, George E., additional, Wray-Lake, Laura, additional, Wu, Li-Tzy, additional, Young, Ross Mc.D., additional, Zvolensky, Michael J., additional, and Zvorsky, Ivori, additional

Published
2013
Full Text
View/download PDF

30. Prevalence of marijuana use disorder in the United States

Author

Compton, Wilson M., Grant, Bridget F., Colliver, James D., Glantz, Meyer D., and Stinson, Frederick S.

Subjects
Market trend/market analysis, Substance abuse -- Forecasts and trends, Substance abuse -- Usage, Substance abuse -- Research, Marijuana -- Forecasts and trends, Marijuana -- Usage, Marijuana -- Research, United States -- Health aspects
Abstract

Changes in the prevalence of marijuana use, abuse and its dependence in the United States is discussed. Even after the stability of marijuana use most adults face disorder in the United States.

Published
2004

32. Introduction to the special issue on the impact of childhood psychopathology interventions on subsequent substance abuse: pieces of the puzzle

Author

Glantz, Meyer D.

Subjects
Psychology, Pathological -- Research, Young adults -- Psychological aspects, Substance abuse -- Research, Psychology and mental health
Abstract

Studies of adolescents and adults have reported high levels of co-occurrence of substance abuse with other psychiatric disorders, suggesting influence between the conditions. The comorbidity seems complex and variable, indicating that there may be more than 1 type of association between the comorbid disorders. When occurring in childhood, some of the frequently comorbid psychopathologics typically precede later drug and alcohol abuse and may have implications for substance abuse prevention as early risk indicators and as targets for intervention. Research discussed in this article and in this special issue provides a foundation for investigating the question of whether effective treatment of childhood psychopathologics can prevent or at least mitigate substance abuse for some adolescents. Clinical, research, and policy implications are discussed.

Published
2002

35. Adolescent substance abuse: a review of the past 10 years

Author

Weinberg, Naimah Z., Rahdert, Elizabeth, Colliver, James D., and Glantz, Meyer D.

Subjects
Teenagers -- Drug use, Substance abuse -- Research, Drugs and youth -- Research, Drug abuse -- Research, Family and marriage, Psychology and mental health
Published
1998

37. Image processing and analysis methods for the Adolescent Brain Cognitive Development Study.

Author

Cornejo, M, Cornejo, M, Makowski, Carolina, Fair, Damien, Dick, Anthony, Sutherland, Matthew, Casey, B, Barch, Deanna, Harms, Michael, Watts, Richard, Bjork, James, Garavan, Hugh, Hilmer, Laura, Pung, Christopher, Sicat, Chelsea, Kuperman, Joshua, Bartsch, Hauke, Xue, Feng, Heitzeg, Mary, Laird, Angela, Trinh, Thanh, Gonzalez, Raul, Neale, Michael, Herting, Megan, Sowell, Elizabeth, Alvarez, Ruben, Hawes, Samuel, Sanchez, Mariana, Bodurka, Jerzy, Breslin, Florence, Morris, Amanda, Paulus, Martin, Simmons, W, Polimeni, Jonathan, van der Kouwe, Andre, Nencka, Andrew, Gray, Kevin, Pierpaoli, Carlo, Matochik, John, Noronha, Antonio, Aklin, Will, Conway, Kevin, Glantz, Meyer, Hoffman, Elizabeth, Little, Roger, Lopez, Marsha, Pariyadath, Vani, Weiss, Susan, Wolff-Hughes, Dana, DelCarmen-Wiggins, Rebecca, Feldstein Ewing, Sarah, Miranda-Dominguez, Oscar, Nagel, Bonnie, Perrone, Anders, Sturgeon, Darrick, Goldstone, Aimee, Pfefferbaum, Adolf, Pohl, Kilian, Prouty, Devin, Shilling, Paul, Desikan, Rahul, Li, Yi, Sugrue, Leo, Banich, Marie, Friedman, Naomi, Hewitt, John, Hopfer, Christian, Sakai, Joseph, Tanabe, Jody, Cottler, Linda, Nixon, Sara, Chang, Linda, Cloak, Christine, Ernst, Thomas, Reeves, Gloria, Kennedy, David, Heeringa, Steve, Peltier, Scott, Schulenberg, John, Sripada, Chandra, Zucker, Robert, Iacono, William, Luciana, Monica, Calabro, Finnegan, Clark, Duncan, Lewis, David, Luna, Beatriz, Schirda, Claudiu, Brima, Tufikameni, Foxe, John, Freedman, Edward, Mruzek, Daniel, Mason, Michael, Huber, Rebekah, McGlade, Erin, Prescot, Andrew, Renshaw, Perry, Riedel, Michael, Squeglia, Lindsay, Hyde, Luke, Rosenberg, Monica, Cornejo, M, Cornejo, M, Makowski, Carolina, Fair, Damien, Dick, Anthony, Sutherland, Matthew, Casey, B, Barch, Deanna, Harms, Michael, Watts, Richard, Bjork, James, Garavan, Hugh, Hilmer, Laura, Pung, Christopher, Sicat, Chelsea, Kuperman, Joshua, Bartsch, Hauke, Xue, Feng, Heitzeg, Mary, Laird, Angela, Trinh, Thanh, Gonzalez, Raul, Neale, Michael, Herting, Megan, Sowell, Elizabeth, Alvarez, Ruben, Hawes, Samuel, Sanchez, Mariana, Bodurka, Jerzy, Breslin, Florence, Morris, Amanda, Paulus, Martin, Simmons, W, Polimeni, Jonathan, van der Kouwe, Andre, Nencka, Andrew, Gray, Kevin, Pierpaoli, Carlo, Matochik, John, Noronha, Antonio, Aklin, Will, Conway, Kevin, Glantz, Meyer, Hoffman, Elizabeth, Little, Roger, Lopez, Marsha, Pariyadath, Vani, Weiss, Susan, Wolff-Hughes, Dana, DelCarmen-Wiggins, Rebecca, Feldstein Ewing, Sarah, Miranda-Dominguez, Oscar, Nagel, Bonnie, Perrone, Anders, Sturgeon, Darrick, Goldstone, Aimee, Pfefferbaum, Adolf, Pohl, Kilian, Prouty, Devin, Shilling, Paul, Desikan, Rahul, Li, Yi, Sugrue, Leo, Banich, Marie, Friedman, Naomi, Hewitt, John, Hopfer, Christian, Sakai, Joseph, Tanabe, Jody, Cottler, Linda, Nixon, Sara, Chang, Linda, Cloak, Christine, Ernst, Thomas, Reeves, Gloria, Kennedy, David, Heeringa, Steve, Peltier, Scott, Schulenberg, John, Sripada, Chandra, Zucker, Robert, Iacono, William, Luciana, Monica, Calabro, Finnegan, Clark, Duncan, Lewis, David, Luna, Beatriz, Schirda, Claudiu, Brima, Tufikameni, Foxe, John, Freedman, Edward, Mruzek, Daniel, Mason, Michael, Huber, Rebekah, McGlade, Erin, Prescot, Andrew, Renshaw, Perry, Riedel, Michael, Squeglia, Lindsay, Hyde, Luke, and Rosenberg, Monica

Abstract

The Adolescent Brain Cognitive Development (ABCD) Study is an ongoing, nationwide study of the effects of environmental influences on behavioral and brain development in adolescents. The main objective of the study is to recruit and assess over eleven thousand 9-10-year-olds and follow them over the course of 10 years to characterize normative brain and cognitive development, the many factors that influence brain development, and the effects of those factors on mental health and other outcomes. The study employs state-of-the-art multimodal brain imaging, cognitive and clinical assessments, bioassays, and careful assessment of substance use, environment, psychopathological symptoms, and social functioning. The data is a resource of unprecedented scale and depth for studying typical and atypical development. The aim of this manuscript is to describe the baseline neuroimaging processing and subject-level analysis methods used by ABCD. Processing and analyses include modality-specific corrections for distortions and motion, brain segmentation and cortical surface reconstruction derived from structural magnetic resonance imaging (sMRI), analysis of brain microstructure using diffusion MRI (dMRI), task-related analysis of functional MRI (fMRI), and functional connectivity analysis of resting-state fMRI. This manuscript serves as a methodological reference for users of publicly shared neuroimaging data from the ABCD Study.

Published
2019

43. The impact of cohort substance use upon likelihood of transitioning through stages of alcohol and cannabis use and use disorder: Findings from the Australian National Survey on Mental Health and Well-Being

Author

Degenhardt, Louisa, Glantz, Meyer, Bharat, Chrianna, Peacock, Amy, Lago, Luise, Sampson, Nancy, and Kessler, Ronald C.

Subjects
Adult, Aged, 80 and over, Male, Marijuana Abuse, Adolescent, Substance-Related Disorders, Australia, Middle Aged, Health Surveys, Article, Cohort Studies, Alcoholism, Young Adult, Mental Health, Prevalence, Humans, Female, Age of Onset, Aged
Abstract

BACKGROUND: We used population-level Australian data to estimate prevalence, age of onset and speed of transitions across stages of alcohol and cannabis use, abuse and dependence, and remission from disorder, and consider the potential impacts that an individual’s age cohort’s level of substance use predicted transitions into and out of substance use. METHODS: Data on use, DSM-IV use disorders, and remission from these disorders were collected from participants (n=8463) in the 2007 Australian National Survey of Mental Health and Wellbeing using the Composite International Diagnostic Interview. RESULTS: Lifetime prevalence (95% confidence interval) of alcohol use, regular use, abuse and dependence were 94.1% (93.3–94.8%), 64.5% (62.9–66.2%), 18.7% (17.4–19.9%) and 4.0% (3.4–4.6%). Lifetime prevalence (standard error) of cannabis use, abuse and dependence were 19.8% (18.6–20.9%), 4.4% (3.8–5.0%) and 1.9% (1.5–2.4%). Among those with the disorder, rates of remission from cannabis abuse, alcohol abuse, cannabis dependence and alcohol dependence were 90.5% (87.4–93.6%), 86.2% (83.8–88.7%), 79.6% (71.1–88.1%) and 53.8% (46.6–61.0%). Increases in the estimated proportion of people in the respondent’s age cohort who used alcohol/cannabis as of a given age were significantly associated with most transitions from use through to remission beginning at the same age. CONCLUSIONS: Clear associations were documented between cohort-level prevalence of substance use and personal risk of subsequent transitions of from use to greater substance involvement. This relationship remained significant over and above associations involving the individual’s age of initiation. These findings have important implications for our understanding of the causal pathways into and out of problematic substance use.

Published
2018

47. The impact of cohort substance use upon likelihood of transitioning through stages of alcohol and cannabis use and use disorder: Findings from the Australian National Survey on Mental Health and Wellbeing

Author

Degenhardt, Louisa, Glantz, Meyer D, Bharat, Chrianna, Peacock, Amy, Lago, Luise P, Sampson, Nancy A, Kessler, Ronald C, Degenhardt, Louisa, Glantz, Meyer D, Bharat, Chrianna, Peacock, Amy, Lago, Luise P, Sampson, Nancy A, and Kessler, Ronald C

Abstract

Introduction and Aims: We used population‐level Australian data to estimate prevalence, age of onset and speed of transitions across stages of alcohol and cannabis use, abuse and dependence, and remission from disorder, and consider the potential impacts that an individual's age cohort's level of substance use predicted transitions into and out of substance use. Design and Methods: Data on use, DSM‐IV use disorders, and remission from these disorders were collected from participants (n = 8463) in the 2007 Australian National Survey of Mental Health and Wellbeing using the Composite International Diagnostic Interview. Results: Lifetime prevalence (95% confidence interval) of alcohol use, regular use, abuse and dependence were 94.1% (93.3-94.8%), 64.5% (62.9-66.2%), 18.7% (17.4-19.9%) and 4.0% (3.4-4.6%). Lifetime prevalence of cannabis use, abuse and dependence were 19.8% (18.6-20.9%), 4.4% (3.8-5.0%) and 1.9% (1.5-2.4%). Among those with the disorder, rates of remission from cannabis abuse, alcohol abuse, cannabis dependence and alcohol dependence were 90.5% (87.4-93.6%), 86.2% (83.8-88.7%), 79.6% (71.1-88.1%) and 53.8% (46.6-61.0%). Increases in the estimated proportion of people in the respondent's age cohort who used alcohol/cannabis as of a given age were significantly associated with most transitions from use through to remission beginning at the same age. Discussion and Conclusions: Clear associations were documented between cohort‐level prevalence of substance use and personal risk of subsequent transitions of individuals in the cohort from use to greater substance involvement. This relationship remained significant over and above associations involving the individual's age of initiation. These findings have important implications for our understanding of the causal pathways into and out of problematic substance use.

Published
2018

48. an analysis of data from the World Mental Health Surveys

Author

Degenhardt, Louisa, Glantz, Meyer D., Evans-Lacko, Sara, Sadikova, Ekaterina, Sampson, Nancy, Thornicroft, Graham, Aguilar-Gaxiola, Sergio, Al-Hamzawi, Ali, Alonso, Jordi, Helena Andrade, Laura, Bruffaerts, Ronny, Bunting, Brendan, Bromet, Evelyn J., de Girolamo, Giovanni, Florescu, Silvia, Gureje, Oye, Maria Haro, Josep, Huang, Yueqin, Karam, Aimee Nasser, Karam, Elie G., Kiejna, Andrzej, Lee, Sing, Lepine, Jean Pierre, Levinson, Daphna, Elena Medina-Mora, Maria, Nakamura, Yosikazu, Navarro-Mateu, Fernando, Pennell, Beth Ellen, Posada-Villa, José, Scott, Kate M., Stein, Dan J., ten Have, Margreet, Torres, Yolanda, Zarkov, Zahari, Chatterji, Somnath, Kessler, Ronald C., Adamowski, Tomasz, Al-Kaisy, Mohammad, Altwaijri, Yasmin, Andrade, Laura Helena, Atwoli, Lukoye, Auerbach, Randy P., Axinn, William G., Benjet, Corina, Borges, Guilherme, Caldas-de-Almeida, José M, Cardoso, Graça, on behalf of the World Health Organization's World Mental Health Surveys collaborators, Centro de Estudos de Doenças Crónicas (CEDOC), and NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)

Subjects
Psychiatry and Mental health, treatment coverage, SDG 3 - Good Health and Well-being, alcohol, Phychiatric Mental Health, United Nations Sustainable Development Goals, World Health Organization, drugs, Substance use disorders
Abstract

Funding: The authors are grateful to M. Kumvaj for her assistance with the systematic literature search. They also thank the staff of the WMHS Data Collection and Data Analysis Coordination Centres for assistance with instrumentation, fieldwork and consultation on data analysis. The WHO’s WMHS are supported by the US National Institute of Mental Health (R01 MH070884), the MacArthur Foundation, the Pfizer Foundation, the US Public Health Service (R13-MH066849, R01-MH069864 and R01 DA016558), the Fogarty International Center (R03-TW006481), the Pan American Health Organization, Eli Lilly and Company, Ortho-McNeil Pharmaceutical Inc., GlaxoSmithKline, Bristol-Myers Squibb, and Shire. The views expressed in this report are those of the authors and should not be construed to represent the views or policies of the WHO, other sponsoring organizations, agencies, or governments. This work was supported by an Australian National Health and Medical Research Council (NHMRC) project grant (no. 1081984). L. Degenhardt is supported by an NHMRC Principal Research Fellowship (no. 1041472). Substance use is a major cause of disability globally. This has been recognized in the recent United Nations Sustainable Development Goals (SDGs), in which treatment coverage for substance use disorders is identified as one of the indicators. There have been no estimates of this treatment coverage cross-nationally, making it difficult to know what is the baseline for that SDG target. Here we report data from the World Health Organization (WHO)'s World Mental Health Surveys (WMHS), based on representative community household surveys in 26 countries. We assessed the 12-month prevalence of substance use disorders (alcohol or drug abuse/dependence); the proportion of people with these disorders who were aware that they needed treatment and who wished to receive care; the proportion of those seeking care who received it; and the proportion of such treatment that met minimal standards for treatment quality (“minimally adequate treatment”). Among the 70,880 participants, 2.6% met 12-month criteria for substance use disorders; the prevalence was higher in upper-middle income (3.3%) than in high-income (2.6%) and low/lower-middle income (2.0%) countries. Overall, 39.1% of those with 12-month substance use disorders recognized a treatment need; this recognition was more common in high-income (43.1%) than in upper-middle (35.6%) and low/lower-middle income (31.5%) countries. Among those who recognized treatment need, 61.3% made at least one visit to a service provider, and 29.5% of the latter received minimally adequate treatment exposure (35.3% in high, 20.3% in upper-middle, and 8.6% in low/lower-middle income countries). Overall, only 7.1% of those with past-year substance use disorders received minimally adequate treatment: 10.3% in high income, 4.3% in upper-middle income and 1.0% in low/lower-middle income countries. These data suggest that only a small minority of people with substance use disorders receive even minimally adequate treatment. At least three barriers are involved: awareness/perceived treatment need, accessing treatment once a need is recognized, and compliance (on the part of both provider and client) to obtain adequate treatment. Various factors are likely to be involved in each of these three barriers, all of which need to be addressed to improve treatment coverage of substance use disorders. These data provide a baseline for the global monitoring of progress of treatment coverage for these disorders as an indicator within the SDGs. publishersversion published

Published
2017

49. Estimating treatment coverage for people with substance use disorders: an analysis of data from the World Mental Health Surveys

Author

Degenhardt, Louisa, Glantz, Meyer, Evans-Lacko, Sara, Sadikova, Ekaterina, Sampson, Nancy, Thornicroft, Graham, Aguilar-Gaxiola, Sergio, Al-Hamzawi, Ali, Alonso, Jordi, Helena Andrade, Laura, Bruffaerts, Ronny, Bunting, Brendan, Bromet, Evelyn J., Caldas de Almeida, José Miguel, de Girolamo, Giovanni, Florescu, Silvia, Gureje, Oye, Maria Haro, Josep, Huang, Yueqin, Karam, Aimee, Karam, Elie G., Kiejna, Andrzej, Lee, Sing, Lepine, Jean Pierre, Levinson, Daphna, Elena Medina-Mora, Maria, Nakamura, Yosikazu, Navarro-Mateu, Fernando, Pennell, Beth Ellen, Posada-Villa, José, Scott, Kate, Stein, Dan J., ten Have, Margreet, Torres, Yolanda, Zarkov, Zahari, Chatterji, Somnath, Kessler, Ronald C., Adamowski, Tomasz, Al-Kaisy, Mohammad, Altwaijri, Yasmin, Atwoli, Lukoye, Auerbach, Randy P., Axinn, William G., Benjet, Corina, Borges, Guilherme, Cardoso, Graça, Chardoul, Stephanie, de Jonge, Peter, Ormel, Johan, Williams, David R., Developmental Psychology, and Scientific Visualization and Computer Graphics

Subjects
medicine.medical_specialty, World Health Organization, World health, drugs, INJECTING DRUG-USERS, 03 medical and health sciences, 0302 clinical medicine, Treatment quality, DEPENDENCE, Environmental health, medicine, 030212 general & internal medicine, Psychiatry, VERSION, Substance use disorders, BARRIERS, business.industry, alcohol, Middle income countries, ALCOHOL-USE DISORDERS, Research Reports, CARE, SERVICES, Service provider, medicine.disease, Mental health, CANNABIS USE, 030227 psychiatry, Substance abuse, Psychiatry and Mental health, treatment coverage, ONSET, Pshychiatric Mental Health, Substance use, business, United Nations Sustainable Development Goals, Treatment need
Abstract

Substance use is a major cause of disability globally. This has been recognized in the recent United Nations Sustainable Development Goals (SDGs), in which treatment coverage for substance use disorders is identified as one of the indicators. There have been no estimates of this treatment coverage cross-nationally, making it difficult to know what is the baseline for that SDG target. Here we report data from the World Health Organization (WHO)'s World Mental Health Surveys (WMHS), based on representative community household surveys in 26 countries. We assessed the 12-month prevalence of substance use disorders (alcohol or drug abuse/dependence); the proportion of people with these disorders who were aware that they needed treatment and who wished to receive care; the proportion of those seeking care who received it; and the proportion of such treatment that met minimal standards for treatment quality ("minimally adequate treatment"). Among the 70,880 participants, 2.6% met 12-month criteria for substance use disorders; the prevalence was higher in upper-middle income (3.3%) than in high-income (2.6%) and low/lower-middle income (2.0%) countries. Overall, 39.1% of those with 12-month substance use disorders recognized a treatment need; this recognition was more common in high-income (43.1%) than in upper-middle (35.6%) and low/lower-middle income (31.5%) countries. Among those who recognized treatment need, 61.3% made at least one visit to a service provider, and 29.5% of the latter received minimally adequate treatment exposure (35.3% in high, 20.3% in upper-middle, and 8.6% in low/lower-middle income countries). Overall, only 7.1% of those with past-year substance use disorders received minimally adequate treatment: 10.3% in high income, 4.3% in upper-middle income and 1.0% in low/lower-middle income countries. These data suggest that only a small minority of people with substance use disorders receive even minimally adequate treatment. At least three barriers are involved: awareness/perceived treatment need, accessing treatment once a need is recognized, and compliance (on the part of both provider and client) to obtain adequate treatment. Various factors are likely to be involved in each of these three barriers, all of which need to be addressed to improve treatment coverage of substance use disorders. These data provide a baseline for the global monitoring of progress of treatment coverage for these disorders as an indicator within the SDGs.

Published
2017
Full Text
View/download PDF

50. Image processing and analysis methods for the Adolescent Brain Cognitive Development Study

Author

Hagler, Donald J, primary, Hatton, Sean N, additional, Makowski, Carolina, additional, Cornejo, M Daniela, additional, Fair, Damien A, additional, Dick, Anthony Steven, additional, Sutherland, Matthew T, additional, Casey, BJ, additional, Barch, Deanna M, additional, Harms, Michael P, additional, Watts, Richard, additional, Bjork, James M, additional, Garavan, Hugh P, additional, Hilmer, Laura, additional, Pung, Christopher J, additional, Sicat, Chelsea S, additional, Kuperman, Joshua, additional, Bartsch, Hauke, additional, Xue, Feng, additional, Heitzeg, Mary M, additional, Laird, Angela R, additional, Trinh, Thanh T, additional, Gonzalez, Raul, additional, Tapert, Susan F, additional, Riedel, Michael C, additional, Squeglia, Lindsay M, additional, Hyde, Luke W, additional, Rosenberg, Monica D, additional, Earl, Eric A, additional, Howlett, Katia D, additional, Baker, Fiona C, additional, Soules, Mary, additional, Diaz, Jazmin, additional, Leon, Octavio Ruiz de, additional, Thompson, Wesley K, additional, Neale, Michael C, additional, Herting, Megan, additional, Sowell, Elizabeth R, additional, Alvarez, Ruben P, additional, Hawes, Samuel W, additional, Sanchez, Mariana, additional, Bodurka, Jerzy, additional, Breslin, Florence J, additional, Morris, Amanda Sheffield, additional, Paulus, Martin P, additional, Simmons, W Kyle, additional, Polimeni, Jonathan R, additional, Kouwe, Andre van der, additional, Nencka, Andrew S, additional, Gray, Kevin M, additional, Pierpaoli, Carlo, additional, Matochik, John A, additional, Noronha, Antonio, additional, Aklin, Will M, additional, Conway, Kevin, additional, Glantz, Meyer, additional, Hoffman, Elizabeth, additional, Little, Roger, additional, Lopez, Marsha, additional, Pariyadath, Vani, additional, Weiss, Susan RB, additional, Wolff-Hughes, Dana L, additional, DelCarmen-Wiggins, Rebecca, additional, Ewing, Sarah W Feldstein, additional, Miranda-Dominguez, Oscar, additional, Nagel, Bonnie J, additional, Perrone, Anders J, additional, Sturgeon, Darrick T, additional, Goldstone, Aimee, additional, Pfefferbaum, Adolf, additional, Pohl, Kilian M, additional, Prouty, Devin, additional, Uban, Kristina, additional, Bookheimer, Susan Y, additional, Dapretto, Mirella, additional, Galvan, Adriana, additional, Bagot, Kara, additional, Giedd, Jay, additional, Infante, M Alejandra, additional, Jacobus, Joanna, additional, Patrick, Kevin, additional, Shilling, Paul D, additional, Desikan, Rahul, additional, Li, Yi, additional, Sugrue, Leo, additional, Banich, Marie T, additional, Friedman, Naomi, additional, Hewitt, John K, additional, Hopfer, Christian, additional, Sakai, Joseph, additional, Tanabe, Jody, additional, Cottler, Linda B, additional, Nixon, Sara Jo, additional, Chang, Linda, additional, Cloak, Christine, additional, Ernst, Thomas, additional, Reeves, Gloria, additional, Kennedy, David N, additional, Heeringa, Steve, additional, Peltier, Scott, additional, Schulenberg, John, additional, Sripada, Chandra, additional, Zucker, Robert A, additional, Iacono, William G, additional, Luciana, Monica, additional, Calabro, Finnegan J, additional, Clark, Duncan B, additional, Lewis, David A, additional, Luna, Beatriz, additional, Schirda, Claudiu, additional, Brima, Tufikameni, additional, Foxe, John J, additional, Freedman, Edward G, additional, Mruzek, Daniel W, additional, Mason, Michael J, additional, Huber, Rebekah, additional, McGlade, Erin, additional, Prescot, Andrew, additional, Renshaw, Perry F, additional, Yurgelun-Todd, Deborah A, additional, Allgaier, Nicholas A, additional, Dumas, Julie A, additional, Ivanova, Masha, additional, Potter, Alexandra, additional, Florsheim, Paul, additional, Larson, Christine, additional, Lisdahl, Krista, additional, Charness, Michael E, additional, Fuemmeler, Bernard, additional, Hettema, John M, additional, Steinberg, Joel, additional, Anokhin, Andrey P, additional, Glaser, Paul, additional, Heath, Andrew C, additional, Madden, Pamela A, additional, Baskin-Sommers, Arielle, additional, Constable, R Todd, additional, Grant, Steven J, additional, Dowling, Gayathri J, additional, Brown, Sandra A, additional, Jernigan, Terry L, additional, and Dale, Anders M, additional

Published
2018
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