137 results on '"Giza E"'
Search Results
2. The impact of the Covid-19 pandemic on a Greek cohort of patients with epilepsy
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Giza, E, Lefkopoulou, M, Dimitrakopoulos, D, Karachristianou, S, and Liasidis, C
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Research Article - Abstract
Background: The Covid-19 pandemic, the subsequent lockdown, and the measures of social distancing may have had adverse effects on patients with epilepsy (PWE). This study was designed to assess the pandemic’s psychological impact on the Greek non-infected PWE and possible changes in their seizure control. Method: The patients were evaluated utilizing a semi-structured interview consisting of open questions regarding their demographic, social, and clinical characteristics, followed by five questions (on a scale of 0-10) related to the Covid-19 pandemic, lockdown, and social distancing measures. Anxiety and depression of PWE were screened using the Hospital Anxiety and Depression Scale (HADS), which consists of HADS-Anxiety and HADS-Depression subscales. Results: We evaluated 65 PWE in the outpatient clinic (60 %) or via telephone interview (40 %). None of these patients experienced changes in seizure control. The mean scores of the Covid-19-related questions were 6.1 ± 2.7 (fear of getting infected), 4.7 ± 3.3 (fear of death), 7.1 ± 2.7 (fear of sickness for their relatives), 6.4 ± 3.1 (stress during lockdown), and 3.0 ± 2.9 (fear of antiepileptic drugs unavailability). Thirty-nine (60 %) patients screened positive for anxiety and thirty-three (50.8 %) for depression. Conclusion: The psychological impact of the Covid-19 pandemic, lockdown, and social distancing measures on non-infected PWE was moderate without changes in their seizure control. HIPPOKRATIA 2021, 25 (4):145-150.
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- 2021
3. Glossopharyngeal neuralgia with cardiac syncope: an idiopathic case treated with carbamazepine and duloxetine
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Giza, E., Kyriakou, P., Liasides, C., and Dimakopoulou, A.
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- 2008
4. Injuries in women’s professional soccer
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Giza, E, Mithöfer, K, Farrell, L, Zarins, B, and Gill, T
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- 2005
5. Hip fracture-dislocation in football: a report of two cases and review of the literature
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Giza, E, Mithöfer, K, Matthews, H, and Vrahas, M
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- 2004
6. Pseudarthrosis of the first rib in the overhead athlete
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Mithöfer, K and Giza, E
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- 2004
7. Perhitungan Biaya Satuan (Unit Cost) Berdasarkan Clinical Pathway Bronkopneumonia Anak di RSUP Prof. Dr. R. D. Kandou Manado Periode Juli 2017- Juni 2018
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Christi D. Mambo, Edward Nangoy, and Giza E. E. Arikalang
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Calculation of unit cost could give some information to healthcare policy. Broncho-pneumonia is a lung inflammation disease that occurs in around 30% of babies with high mortality risk. This study was aimed to determine the general depiction of unit cost calculation for bronchopneumonia among pediatric patients at Prof. Dr. R. D. Kandou Hospital according to clinical pathway. This was an observational retrospective study. Samples were obtained by using random sampling as many as 42 samples that fulfilled inclusion criteria. Processed data included patients’ demography, treatment, and the average of direct cost calculation. The results showed that the implemented therapy consisted of antibiotic, non-antibiotic, fluid therapy, ancillary laboratory examination, radiology, and ancillary diagnostics. Total cost for drugs was Rp. 8,822,455; laboratory Rp. 28,568,725; radiology Rp. 9,912,400; and ancillary diagnostic examination Rp. 7,110,000. Compared to the cost covered by BPJS, the hospital had some excess as follows: drug unit Rp. 958,549, radiology Rp. 1,771,517, and ancillary diagnostic examination Rp. 581,852. For ancillary laboratory examination in the hospital, there was a difference as much as Rp. 1,341,276 less than the the BPJS coverage. Conclusion: There was an excess difference within drug unit, radiology, and ancillary examinations for pediatric bronchopneumonia, while laboratorium unit possess lesser cost than BPJS.Keywords: bronchopneumnonia, cost unitAbstrak: Perhitungan biaya satuan merupakan salah satu informasi masukan dalam pembuatan kebijakan pelayanan. Bronkopneumonia ialah penyakit radang paru yang terjadi pada sekitar 30% anak balita dengan risiko kematian yang tinggi. Penelitian ini bertujuan untuk mendapatkan gambaran perhitungan biaya satuan pada pasien bronkopneumonia anak di RSUP Prof. Dr. R. D. Kandou berdasarkan clinical pathway. Jenis penelitian ialah observasional retrospektif. Sampel penelitian dikumpulkan dengan metode random sampling berjumlah 42 sampel yang memenuhi kriteria inklusi. Data meliputi data demografi pasien, gambaran pengobatan, dan penghitungan rata-rata biaya langsung. Hasil penelitian mendapatkan bahwa terapi yang digunakan ialah antibiotik, non antibiotik, terapi cairan, serta penunjang laboratorium, radiologi, dan penunjang diagnostik. Total biaya untuk obat Rp. 8.822.455, laboratorium Rp. 28.568.725, radiologi Rp. 9.912.400, dan penunjang diagnostik Rp. 7.110.000. Bila dibandingkan dengan biaya tanggungan BPJS, rumah sakit memiliki selisih lebih pada unit obat sebanyak Rp. 958.549, radiologi Rp. 1.771.517, dan penunjang diagnostik Rp. 581.852. Untuk penunjang laboratorium, terdapat selisih kurang sebesar Rp. 1.341.276. Simpulan: Pada pengobatan bronkopneumonia anak terdapat perbedaan selisih lebih pada unit obat, radiologi, dan penunjang diagnostik, serta terdapat selisih kurang pada unit laboratoriumKata kunci: bronkopneumonia, perhitungan biaya satuan
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- 2019
8. Dynamic Lisfranc Joint Repair Concept: Surgical Technique for a Synthetic Neoligamentplasty
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Nery, C., primary, Giza, E., additional, Wagner, E., additional, Percope de Andrade, M.A., additional, Soares Baumfeld, T., additional, Pires Prado, M., additional, and Baumfeld, D., additional
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- 2019
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9. Lyme Disease as Farmers’ Occupational Disease. The Evaluation of an Increase in Morbidity Rate Tendency Between 2000 and 2019
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Podstawka Marian and Giza Ewa
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lyme disease ,borrelia ,farmers’ occupational diseases ,lyme disease cases ,signs and/or symptoms ,prophylaxis ,compensations ,a13 ,Regional economics. Space in economics ,HT388 ,Economics as a science ,HB71-74 - Abstract
The aim of this paper is to make an analysis and evaluation of Lyme disease incidence, understood as a diagnosed farmers’ occupational disease.
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- 2023
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10. Perhitungan Biaya Satuan (Unit Cost) Berdasarkan Clinical Pathway Bronkopneumonia Anak di RSUP Prof. Dr. R. D. Kandou Manado Periode Juli 2017- Juni 2018
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Arikalang, Giza E. E., primary, Nangoy, Edward, additional, and Mambo, Christi D., additional
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- 2019
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11. Clinical and Electrodiagnostic Findings in A Cohort of 61 Dogs with Peripheral Nervous System Diseases - A Retrospective Study.
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Giza, E. G., Nicpon, J. E., and Wrzosek, M. A.
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DIAGNOSIS of dog diseases , *ELECTRODIAGNOSIS , *PERIPHERAL nervous system , *MYONEURAL junction , *COHORT analysis , *RETROSPECTIVE studies , *BRAIN imaging - Abstract
The electrodiagnostic examination provides the basis for a diagnostic workup in diseases involving nerve roots, peripheral nerves, neuromuscular junctions and muscles in humans and animals. It is a functional test that enables identification, localization and characterization of the disease within the peripheral nervous system. The study was carried out retrospectively on a group of 61 dogs of different breeds referred for an electrodiagnostic examination because of local or generalized peripheral nervous system impairment. The electrodiagnostic examination consisted of electromyography, electroneurography, F-wave and repetitive nerve stimulation testing. The results of electrodiagnostic studies and their impact on the diagnosis of neuromuscular diseases of different etiology is presented in the study. The lesion was localized to peripheral nerves in 38%, nerve roots in 34%, skeletal muscles in 18% and the neuromuscular junction in 10% of cases. Electrodiagnostics enabled an objective assessment of the extent, distribution and nature of the disease in the study group. However, only when it is used in conjunction with a complete physical and neurological examination and appropriate laboratory or imaging studies, it may be helpful in determining the etiological diagnosis in patients with peripheral nervous system disease. [ABSTRACT FROM AUTHOR]
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- 2014
12. Cartilage transplantation techniques for talar cartilage lesions.
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Mitchell ME, Giza E, Sullivan MR, Mitchell, Matthew E, Giza, Eric, and Sullivan, Martin R
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- 2009
13. Posterior impingement of the ankle caused by anomalous muscles. A report of four cases.
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Best A, Giza E, Linklater J, Sullivan M, Best, Alistair, Giza, Eric, Linklater, James, and Sullivan, Martin
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- 2005
14. Soccer Injuries.
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Giza, E. and Micheli, L.
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- 2005
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15. A radiographic investigation to determine the safety of suture anchor systems for pediatric modified Brostöm ankle ligament reconstruction.
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Hazratwala K, Best A, Kopplin M, Giza E, and Sullivan M
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BACKGROUND: The modified Brostrom ligament reconstruction using anchor sutures has been performed in adults with clinical success; however, the safety parameters for the use of suture anchors in adolescent lateral ankle ligament reconstruction have not been established. PURPOSE: To perform a radiographic analysis comparing the depth of penetration of suture anchors in adult ankle ligament reconstruction with the average distance of the physis from the tip of the fibula in adolescents. STUDY DESIGN: Cross-sectional study, Level of evidence, 4. METHODS: Forty postoperative ankle radiographs of adult patients who had a modified Brostrom procedure were compared with 40 normal adolescent ankle radiographs. In the adult group, the distance of the suture anchor penetration from the distal tip of the fibula was measured; in the adolescent group, the distance of the physis from the distal tip of the fibula was measured. RESULTS: The mean depth of the suture anchors was 17 mm (range, 14-21 mm) from the tip of the fibula in the adult group, and the mean distance of the growth plate was 23 mm (range, 18-29 mm) in the adolescent group. Eight radiographs from the adolescent group (20%) had a physis measurement of <22 mm on the anteroposterior or mortise view. CONCLUSIONS: Using careful preoperative planning and intraoperative technique, it is possible to safely perform lateral ankle ligament repair in the skeletally immature patient using suture anchors. [ABSTRACT FROM AUTHOR]
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- 2005
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16. Acute foot and ankle injuries and time return to sport
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Thevendran Gowreeson, Kadakia Anish R., Giza Eric, Haverkamp Daniel, D’Hooghe Jonkheer Pieter, Veljkovic Andrea, and Abdelatif Nasef Mohamed Nasef
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return to play ,acute foot and ankle injuries ,rehabilitation ,Orthopedic surgery ,RD701-811 - Abstract
Foot and ankle sports injuries encompass a wide spectrum of conditions from simple contusions or sprains that resolve within days to more severe injuries that change the trajectory of an athlete’s sporting career. If missed, severe injuries could lead to prolonged absence from the sport and therefore a catastrophic impact on future performance. In this article, we discuss the presentation of the commonest foot and ankle sports injuries and share recent evidence to support an accurate diagnosis and best management practice.
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- 2021
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17. American Academy of Orthopaedic Surgeons clinical practice guideline on treatment of Achilles tendon rupture.
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Chiodo CP, Glazebrook M, Bluman EM, Cohen BE, Femino JE, Giza E, Watters WC 3rd, Goldberg MJ, Keith M, Haralson RH 3rd, Turkelson CM, Wies JL, Hitchcock K, Raymond L, Anderson S, Boyer K, Sluka P, Chiodo, Christopher P, Glazebrook, Mark, and Bluman, Eric Michael
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- 2010
18. Aggressive giant cell reparative granuloma of the metacarpal: A case report
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Giza, E., Stern, P.J., and Cualing, H.
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A 67-year-old woman presented with pain and swelling over her ring metacarpal. There was no history of antecedent blunt or penetrating injury. X-rays showed a progressively destructive lesion of the metacarpal shaft and base. Subsequent biopsy revealed a giant cell reparative granuloma. Because of her age and the presence of osteorthritis and digital stiffness, a ray amputation was carried out. Follow-up examination 3 years later revealed no evidence of recurrence.
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- 1997
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19. Osteomyelitis of the tubular bones of the hand
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Reilly, K.E., Linz, J.C., Stern, P.J., Giza, E., and Wyrick, J.D.
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The records of 700 patients with hand infections were reviewed. Forty-six (6%) had osteomyelitis of the metacarpals or phalangeal bones. The cause was post-traumatic in 57%, postoperative in 15%, hematogenous in 13%, spread from contiguous infections in 9%, and unidentified in 6%. Twenty-two percent of the patients had vascular insufficiency and/or were immunocompromised. History, physical exam, plain x-rays, and open biopsy and culture were most helpful in establishing the diagnosis. Laboratory studies and bone scans were less helpful. Cultures were positive in 74% of patients, with a noteworthy number of mixed infections (35%) and gram-positive infections (35%). Gram-negative infections accounted for 15%, fungal infections for 12%, and mycobacterial infections for 3%. Surgical management varied from simple curettage to more elaborate staged reconstructions and/or arthrodeses. Despite provision of aggressive surgical care and use of appropriate antibiotics, the overall amputation rate was 39% (18/46). A delay of more than 6 months from onset of symptoms to diagnosis and definitive treatment led to amputation in 6 of 7 patients (86%), 2 of whom had squamous-cell carcinoma. Of the 12 patients who underwent more than 3 surgical procedures, 8 ultimately underwent amputation and 2 had marked disability.
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- 1997
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20. Auditory brainstem evoked response (BAER) in the diagnosis of nervous system diseases in horses,Badanie słuchowych potencjałów wzbudzanych pnia mózgu w diagnostyce zaburzeń układu nerwowego u koni
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Marcin Wrzosek, Niedźwiedź, A., Giza, E., Borowicz, H., and Nicpoń, J.
21. Pupillometric evaluation of patients suffering from age related macular degeneration (AMD): a comparative study with electrophysiological and optical methods
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Giantselidis Charalambos, Nakou Maria, Fotiou Dimitrios, Kalliolia Irene, Tsiptsios Dimitrios, Stergiou Vasilios, Theodoridou Evangelia, Brozou Catherine, and Giza Evangelia
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Psychiatry ,RC435-571 - Published
- 2006
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22. Pupillometry in depressed patients
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Theodoridou Evangelia, Giza Evangelia, Stergiou Vasilios, Brozou Catherine, Kalliolia Irene, Tsiptsios Dimitrios, Fotiou Aggelis, Fotiou Dimitrios, Nakou Maria, and Giantselidis Charalambos
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Psychiatry ,RC435-571 - Published
- 2006
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23. Pupillometry and neuroimaging methods in patients with Parkinson's disease
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Nakou Maria, Fotiou Dimitrios, Kalliolia Irene, Tsiptsios Dimitrios, Stergiou Vasilios, Theodoridou Evangelia, Brozou Catherine, Giza Evangelia, and Giantselidis Charalambos
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Psychiatry ,RC435-571 - Published
- 2006
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24. Myasthenia gravis: a pupillometric study
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Brozou Catherine, Theodoridou Evangelia, Giza Evangelia, Kalliolia Irene, Fotiou Aggelis, Stergiou Vasilios, Nakou Maria, Fotiou Dimitrios, Tsiptsios Dimitrios, and Giantselidis Charalambos
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Psychiatry ,RC435-571 - Published
- 2006
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25. Pupillometry and MRI findings of hippocampus in Alzheimer's disease
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Giantselidis Charalambos, Brozou Catherine, Theodoridou Evangelia, Giza Evangelia, Stergiou Vasilios, Nakou Maria, Tsiptsios Dimitrios, Fotiou Dimitrios, and Kalliolia Irene
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Psychiatry ,RC435-571 - Published
- 2006
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26. Arthroscopic ankle fusion: a change of the "gold standard": Commentary on an article by David Townshend, MBBS, FRCS(Orth), et al.: "Arthroscopic versus open ankle arthrodesis: a multicenter comparative case series".
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Giza E and Giza, Eric
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- 2013
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27. Early Outcomes of Lisfranc Injuries Treated with Arthrex InternalBrace: A Case Series.
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Hoskins M, Wise P, Unangst A, Shaheen P, Kreulen C, Aynardi M, and Giza E
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Introduction: The treatment of Lisfranc injuries continues to evolve with time. The purpose of this study was to report early outcomes of patients with Lisfranc ligamentous injuries treated with the Arthrex InternalBrace, which has benefits to other previously described techniques., Materials and Methods: We retrospectively identified 15 adult patients with Lisfranc injuries that were treated via open reduction internal fixation with the Arthrex InternalBrace (Naples, Fl). These patients were identified at two separate United States institutions between 2019 and 2022. Demographic data, mechanism of injury, and concomitant foot injuries were recorded. Outcomes were assessed by return-to-work or sport and time to weight-bearing. Secondary complications or revision surgeries were noted., Results: The mean patient age was 35 years. Eight patients had isolated Lisfranc ligamentous injuries and seven had additional intercuneiform instability, which required a supplemental limb of the fixation device. The most common mechanism of injury was a cutting/pivoting maneuver ( n = 5) followed by fall ( n = 4). The mean radiographic follow-up time was 7.3 months. The average time to weight-bearing as tolerated was 6.6 weeks (± 2.2). The average time to return-to-work/sport as tolerated was 14.1 weeks (± 3.6). Only two minor complications were noted at follow-up but no major complications or revision surgeries occurred., Conclusions: The outcomes of this case series suggest that the Arthrex InternalBrace is a viable option when performing open reduction and internal fixation of Lisfranc ligamentous injuries. Future prospective studies are needed to directly compare this device with alternative fixation methods., Competing Interests: Conflict of InterestThe authors declare that no funds, grants, or other support were received during the preparation of this manuscript. Hoskins, Wise, Unangst, and Shaheen have no financial interests. Kreulen, Aynardi, and Giza have previously received funding for research and for general consulting from Arthrex Inc. but no direct funding or incentives were provided for conducting this particular investigation., (© This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2024.)
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- 2024
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28. Aseptic Meningitis Linked to Borrelia afzelii Seroconversion in Northeastern Greece: An Emerging Infectious Disease Contested in the Region.
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Kouroupis D, Terzaki M, Moscha N, Sarvani A, Simoulidou E, Chatzimichailidou S, Giza E, Sapouridis G, Angelakis E, Petidis K, and Pyrpasopoulou A
- Abstract
Borreliosis (Lyme disease) is a zoonosis, mediated to humans and small mammals through specific vectors (ticks), with increasing global incidence. It is associated with a variety of clinical manifestations and can, if not promptly recognized and left untreated, lead to significant disability. In Europe, the main Borrelia species causing disease in humans are Borrelia burgdorferi s.s. , Borrelia afzelii , Borrelia garinii , and Borrelia spielmanii . The Ixodes ricinus tick is their principal vector. Although Lyme disease is considered endemic in the Balkan region and Turkey, and all three main Lyme pathogens have been detected in ticks collected in these countries, autochthonous Lyme disease remains controversial in Greece. We report a case of aseptic meningitis associated with antibody seroconversion against Borrelia afzelii in a young female patient from the prefecture of Thasos without any relevant travel history. The patient presented with fever and severe headache, and the cerebrospinal fluid examination showed lymphocytic pleocytosis. Serum analysis was positive for specific IgG antibodies against Borrelia afzelii . In the absence of typical erythema migrans, serological evidence of infection is required for diagnosis. Although atypical in terms of clinical presentation, the seasonality and geographical location of potential disease transmission in the reported patient should raise awareness among clinicians for a still controversial and potentially underreported emerging infectious disease in Greece.
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- 2024
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29. Scope of the Problem: Ankle Arthroscopy.
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Lausé GE, Smith JT, Bluman EM, Martin EA, Giza E, and Chiodo CP
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- Humans, Ankle, Ankle Joint, Ankle Injuries, Arthroscopy methods
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Ankle arthroscopy has seen increased utilization and application in recent years. Through the advent of improved instrumentation and techniques, indications have been expanded to include the management of traumatic, degenerative, inflammatory, and neoplastic conditions. It is important to review anterior and posterior ankle arthroscopies along with the history, pertinent anatomy, techniques, indications, and complications as well as gain insight into the future of ankle arthroscopy.
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- 2023
30. Scope of the Problem: Tendoscopy and Small Joint Arthroscopy of the Foot and Ankle.
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Boakye LAT, Martin EA, Chiodo CP, Giza E, Bluman EM, and Smith JT
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- Humans, Treatment Outcome, Ankle Joint surgery, Arthroscopy methods, Ankle
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It is important to identify and describe practical applications of arthroscopy in the management of foot and ankle pathology. Utilization of the arthroscope provides a minimally invasive means of evaluating and addressing pathology. It obviates the need for a large open approach, which has additional value in the setting of a multiprocedure surgery. In addition to reducing surgical time, arthroscopy provides a potentially enhanced field of view and an adequate working space to address injury. As interest in minimally invasive options grows, the need for safe, effective tendoscopic and arthroscopic options in the foot and ankle increases. A clear and high-yield reference is needed with which to approach these procedures.
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- 2023
31. Paediatric ankle cartilage lesions: Proceedings of the International Consensus Meeting on Cartilage Repair of the Ankle.
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Hurley DJ, Davey MS, Hurley ET, Murawski CD, Calder JDF, D'Hooghe P, van Bergen CJA, Walls RJ, Ali Z, Altink JN, Batista J, Bayer S, Berlet GC, Buda R, Dahmen J, DiGiovanni CW, Ferkel RD, Gianakos AL, Giza E, Glazebrook M, Guillo S, Hangody L, Haverkamp D, Hintermann B, Hogan MV, Hua Y, Hunt K, Jamal MS, Karlsson J, Kearns S, Kerkhoffs GMMJ, Lambers K, Lee JW, McCollum G, Mercer NP, Mulvin C, Nunley JA, Paul J, Pearce C, Pereira H, Prado M, Raikin SM, Savage-Elliott I, Schon LC, Shimozono Y, Stone JW, Stufkens SAS, Sullivan M, Takao M, Thermann H, Thordarson D, Toale J, Valderrabano V, Vannini F, van Dijk CN, Walther M, Yasui Y, Younger AS, and Kennedy JG
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- Humans, Child, Ankle, Ankle Joint surgery, Cartilage, Articular surgery, Ankle Injuries surgery
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Background: The evidence supporting best practice guidelines in the field of cartilage repair of the ankle are based on both low quality and low levels of evidence. Therefore, an international consensus group of experts was convened to collaboratively advance toward consensus opinions based on the best available evidence on key topics within cartilage repair of the ankle. The purpose of this article is to report the consensus statements on "Pediatric Ankle Cartilage Lesions" developed at the 2019 International Consensus Meeting on Cartilage Repair of the Ankle., Methods: Forty-three international experts in cartilage repair of the ankle representing 20 countries convened to participate in a process based on the Delphi method of achieving consensus. Questions and statements were drafted within four working groups focusing on specific topics within cartilage repair of the ankle, after which a comprehensive literature review was performed and the available evidence for each statement was graded. Discussion and debate occurred in cases where statements were not agreed upon in unanimous fashion within the working groups. A final vote was then held, and the strength of consensus was characterised as follows: consensus: 51-74%; strong consensus: 75-99%; unanimous: 100%., Results: A total of 12 statements on paediatric ankle cartilage lesions reached consensus during the 2019 International Consensus Meeting on Cartilage Repair of the Ankle. Five achieved unanimous support, and seven reached strong consensus (>75% agreement). All statements reached at least 84% agreement., Conclusions: This international consensus derived from leaders in the field will assist clinicians with the management of paediatric ankle cartilage lesions., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2022 The Author(s). Published by Elsevier Inc. All rights reserved.)
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- 2022
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32. Terminology for osteochondral lesions of the ankle: proceedings of the International Consensus Meeting on Cartilage Repair of the Ankle.
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Murawski CD, Jamal MS, Hurley ET, Buda R, Hunt K, McCollum G, Paul J, Vannini F, Walther M, Yasui Y, Ali Z, Altink JN, Batista J, Bayer S, Berlet GC, Calder JDF, Dahmen J, Davey MS, D'Hooghe P, DiGiovanni CW, Ferkel RD, Gianakos AL, Giza E, Glazebrook M, Hangody L, Haverkamp D, Hintermann B, Hua Y, Hurley DJ, Karlsson J, Kearns S, Kennedy JG, Kerkhoffs GMMJ, Lambers K, Lee JW, Mercer NP, Mulvin C, Nunley JA, Pearce C, Pereira H, Prado M, Raikin SM, Savage-Elliott I, Schon LC, Shimozono Y, Stone JW, Stufkens SAS, Sullivan M, Takao M, Thermann H, Thordarson D, Toale J, Valderrabano V, van Bergen CJA, van Dijk CN, Walls RJ, Younger AS, and Hogan MV
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- Ankle, Ankle Joint surgery, Humans, Ankle Injuries surgery, Cartilage, Articular injuries, Cartilage, Articular surgery, Intra-Articular Fractures, Talus injuries, Talus surgery
- Abstract
Background: The evidence supporting best practice guidelines in the field of cartilage repair of the ankle is based on both low quality and low levels of evidence. Therefore, an international consensus group of experts was convened to collaboratively advance toward consensus opinions based on the best available evidence on key topics within cartilage repair of the ankle. The purpose of this article is to report the consensus statements on "terminology for osteochondral lesions of the ankle" developed at the 2019 International Consensus Meeting on Cartilage Repair of the Ankle., Methods: Forty-three international experts in cartilage repair of the ankle representing 20 countries were convened and participated in a process based on the Delphi method of achieving consensus. Questions and statements were drafted within four working groups focusing on specific topics within cartilage repair of the ankle, after which a comprehensive literature review was performed, and the available evidence for each statement was graded. Discussion and debate occurred in cases where statements were not agreed on in unanimous fashion within the working groups. A final vote was then held, and the strength of consensus was characterised as follows: consensus, 51%-74%; strong consensus, 75%-99%; unanimous, 100%., Results: A total of 11 statements on terminology and classification reached consensus during the 2019 International Consensus Meeting on Cartilage Repair of the Ankle. Definitions are provided for osseous, chondral and osteochondral lesions, as well as bone marrow stimulation and injury chronicity, among others. An osteochondral lesion of the talus can be abbreviated as OLT., Conclusions: This international consensus derived from leaders in the field will assist clinicians with the appropriate terminology for osteochondral lesions of the ankle., (Copyright © 2021 The Author(s). Published by Elsevier Inc. All rights reserved.)
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- 2022
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33. Incidence of Injury for Professional Soccer Players in the United States: A 6-Year Prospective Study of Major League Soccer.
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Forsythe B, Knapik DM, Crawford MD, Diaz CC, Hardin D, Gallucci J, Silvers-Granelli HJ, Mandelbaum BR, Lemak L, Putukian M, and Giza E
- Abstract
Background: Despite an abundance of injury research focusing on European professional soccer athletes, there are limited injury data on professional soccer players in the United States., Purpose: To describe the epidemiology of injury across multiple years in Major League Soccer (MLS) players., Study Design: Descriptive epidemiology study., Methods: A web-based health management platform was used to prospectively collect injury data from all MLS teams between 2014 and 2019. An injury was defined as an incident that required medical attention and was recorded into the health management platform anytime over the course of the 2014-2019 seasons. Injuries and exposure data were recorded in training and match settings to calculate injury incidence., Results: A total of 9713 injuries were recorded between 2014 and 2019. A mean 1.1 injuries per year per player were identified, with midfielders sustaining the largest number of injuries. The most common injuries were hamstring strains (12.3%), ankle sprains (8.5%), and adductor strains (7.6%). The mean time missed per injury was 15.8 days, with 44.2% of injuries resulting in no days missed. Overall injury incidence was 8.7 per 1000 hours of exposure, declining over the course of the investigation, with a 4.1-times greater mean incidence during matches (14.0/1000 h) than training (3.4/1000 h)., Conclusion: Between 2014 and 2019, the most commonly reported injuries in MLS players were hamstring strains, ankle sprains, and adductor strains. Injury incidence during matches was 4.1 times greater when compared with training, while overall injury incidence was found to decline during the course of the study period., Competing Interests: One or more of the authors has declared the following potential conflict of interest or source of funding: B.F. has received grants from Arthrex and Stryker, research support from Smith & Nephew, education payments from Medwest, consulting fees from Stryker, and personal fees from Elsevier and has stock/stock options in Jace Medical. M.D.C. has received education payments from Smith & Nephew and hospitality payments from Abbott, Misonix, and Stryker. D.H. has received hospitality payments from Horizon Pharma and Sentnyl Therapeutics. B.R.M. has received consulting fees from Arthrex, Biomarin, DePuy, and Exactech; speaking fees from Arthrex; and hospitality payments from Aesculap, Bioventus, Ferring, Flexion, Sanofi, and Stryker. L.L. has received consulting fees from Aesculap and hospitality payments from Ferring, Fidia, Flexion, Orthofix, Pacira, Sanofi, and Si-bone. E.G. has received education payments from Sequoia; consulting fees from Arthrex, Ipsen, MedShape, and Zimmer; royalties from Arthrex and Zimmer; honoraria from In2Bones; and hospitality payments from ACELL, Evolution Surgical, Integra, Steelhead Surgical, and Stryker. AOSSM checks author disclosures against the Open Payments Database (OPD). AOSSM has not conducted an independent investigation on the OPD and disclaims any liability or responsibility relating thereto., (© The Author(s) 2022.)
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- 2022
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34. Osteochondral Lesions of the Tibial Plafond and Ankle Instability With Ankle Cartilage Lesions: Proceedings of the International Consensus Meeting on Cartilage Repair of the Ankle.
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Dahmen J, Bayer S, Toale J, Mulvin C, Hurley ET, Batista J, Berlet GC, DiGiovanni CW, Ferkel RD, Hua Y, Kearns S, Lee JW, Pearce CJ, Pereira H, Prado MP, Raikin SM, Schon LC, Stone JW, Sullivan M, Takao M, Valderrabano V, van Dijk CN, Ali Z, Altink JN, Buda R, Calder JDF, Davey MS, D'Hooghe P, Gianakos AL, Giza E, Glazebrook M, Hangody L, Haverkamp D, Hintermann B, Hogan MV, Hunt KJ, Hurley DJ, Jamal MS, Karlsson J, Kennedy JG, Kerkhoffs GMMJ, Lambers KTA, McCollum G, Mercer NP, Nunley JA 2nd, Paul J, Savage-Elliott I, Shimozono Y, Stufkens SAS, Thermann H, Thordarson D, Vannini F, van Bergen CJA, Walls RJ, Walther M, Yasui Y, Younger ASE, and Murawski CD
- Subjects
- Ankle, Ankle Joint surgery, Humans, Ankle Injuries surgery, Cartilage, Articular surgery, Joint Instability surgery
- Abstract
Background: An international consensus group of experts was convened to collaboratively advance toward consensus opinions based on the best available evidence on key topics within cartilage repair of the ankle. The purpose of this article is to present the consensus statements on osteochondral lesions of the tibial plafond (OLTP) and on ankle instability with ankle cartilage lesions developed at the 2019 International Consensus Meeting on Cartilage Repair of the Ankle., Methods: Forty-three experts in cartilage repair of the ankle were convened and participated in a process based on the Delphi method of achieving consensus. Questions and statements were drafted within 4 working groups focusing on specific topics within cartilage repair of the ankle, after which a comprehensive literature review was performed and the available evidence for each statement was graded. Discussion and debate occurred in cases where statements were not agreed on in unanimous fashion within the working groups. A final vote was then held., Results: A total of 11 statements on OLTP reached consensus. Four achieved unanimous support and 7 reached strong consensus (greater than 75% agreement). A total of 8 statements on ankle instability with ankle cartilage lesions reached consensus during the 2019 International Consensus Meeting on Cartilage Repair of the Ankle. One achieved unanimous support, and seven reached strong consensus (greater than 75% agreement)., Conclusion: These consensus statements may assist clinicians in the management of these difficult clinical pathologies., Level of Evidence: Level V, mechanism-based reasoning.
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- 2022
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35. Malignant neoplasms originating from the bones of the foot: Predilection of hematological malignancies and sex-related and ethnic disparities in amputation.
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Jawad MU, Farhan SB, Haffner MR, Kreulen CD, Giza E, Thorpe SW, and Randall RL
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- Adolescent, Adult, Aged, Bone Neoplasms complications, California epidemiology, Child, Child, Preschool, Cohort Studies, Female, Follow-Up Studies, Foot Diseases complications, Hematologic Neoplasms etiology, Hematologic Neoplasms surgery, Humans, Incidence, Infant, Infant, Newborn, Male, Middle Aged, Neoplasms etiology, Neoplasms surgery, Prognosis, SEER Program, Sex Factors, Young Adult, Amputation, Surgical statistics & numerical data, Bone Neoplasms epidemiology, Ethnicity statistics & numerical data, Foot Diseases epidemiology, Hematologic Neoplasms pathology, Neoplasms pathology
- Abstract
Purpose: Neoplasms originating from the "small bones of the lower limb and the overlapping joints" are rare but portend a serious prognosis. Current study utilizes a population-based registry in the United States to characterize the malignancies of the foot., Methods: National Cancer Institute's Surveillance, Epidemiology and End Result database from 1975 to 2017 was queried to report incidence and survival data in 514 patients in the Uited States. Kaplan-Meier and Cox Regression were used to determine the prognostic factors affecting survival. Chi square test was used to assess the correlation., Results: Hematological malignancies constituted 14.8% of the entire cohort. Incidence of the foot neoplasms was 0.024 per 100 000 persons in 2017 and has not significantly changed since 1975 (p > 0.05). Disease-specific-5-year survival for the entire cohort was 73%. On multivariate analysis younger age groups, "localized" stage and extent of surgical resection were predictors of improved outcomes. A significant correlation was found between amputation with male sex and Hispanic ethnicity., Conclusions: The current study analyzes data from population-based registry reporting incidence and survival data for patients with neoplasms of the foot. Independent prognostic factors include age, stage and extent of surgical resection. Amputation was found to be associated with male sex and Hispanic ethnicity., (© 2021 Wiley Periodicals LLC.)
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- 2021
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36. Surgical Treatment for Osteochondral Lesions of the Talus.
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Powers RT, Dowd TC, and Giza E
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- Bone Transplantation, Humans, Transplantation, Autologous, Ankle Injuries surgery, Cartilage, Articular surgery, Talus surgery
- Abstract
Osteochondral lesions of the talus (OLT) are often associated with ankle pain and dysfunction. They can occur after ankle trauma, such as sprains or fractures, but they usually present as a continued ankle pain after the initial injury has resolved. Chronic ankle ligament instability and subsequent microtrauma may lead to insidious development of an OLT. Medial-sided lesions are more common (67%) than lateral-sided lesions. For acute lesions that are nondisplaced, nonoperative management is initially performed, with a 4-6 week period of immobilization and protected weight bearing. Symptomatic improvement results in more than 50% of patients by 3 months. Acute osteochondral talus fractures, which have a bone fragment thickness greater than 3 mm with displacement will benefit from early surgical intervention. These injuries should undergo primary repair via internal fixation with bioabsorbable compression screws 3.0 mm or smaller using at least 2 points of fixation. Acute lesions that are too small for fixation can be treated with morselization and reimplantation of the cartilage fragments. If OLTs are persistently symptomatic following an appropriate course of nonoperative treatment, various reparative and restorative surgical options may be considered on the basis of diameter, surface area, depth, and location of the lesion. A small subset of symptomatic osteochondral lesions of the talus involve subchondral pathology with intact overlying articular cartilage; in these cases, retrograde drilling into the cystic lesion can be employed to induce underlying bony healing. Cancellous bone graft augmentation may be used for subchondral cysts with volume greater than 100 mm
3 or with those with a depth of more than 10 mm. Debridement, curettage, and bone marrow stimulation is a reparative technique that may be considered in lesions demonstrating a diameter less than 10 mm, with surface area less than 100 mm2 , and a depth less than 5 mm. This technique is commonly performed arthroscopically using curettes and an arthroscopic shaver to remove surrounding unstable cartilage. A microfracture awl of 1 mm or less is used to puncture the subchondral bone with 3-4 mm of spacing between to induce punctate bleeding. Initial (<5 year) results are good to excellent in 80% of cases, with some deterioration of improvement over time. Factors contributing to poor results include surface area greater than 1.5 cm2 , overall osteochondral lesion depth over 7.8 mm, smoking history, age over 40, and uncontained lesions. Lesions greater than 1.29 cm2 , cystic lesions, and lesions that have failed prior treatment are potential candidates for osteochondral autograft transplantation. The autograft is typically harvested from the lateral femoral condyle of the ipsilateral knee with an optimal plug depth and diameter of 12-15 mm. Transplantation often involves open technique and may even require malleolar osteotomy for perpendicular access to the defect, as well as visualization of a flush, congruent graft fit. Good to excellent outcomes have been reported in up 87.4% of cases with the most common complication being donor site morbidity in up to 15% of cases. Failure rates increased significantly in lesions larger than 225 mm2 . Scaffold-based therapies, such as matrix-associated chondrocyte implantation, can be employed in primary or revision settings in lesions larger than 1 cm2 , including uncontained shoulder lesions with or without cysts. Lesions with greater than 4 mm of bone loss following debridement may require bone grafting to augment with the scaffold. This technique requires an initial procedure for chondrocyte harvest and a secondary procedure for transplantation of the scaffold. Outcomes have been good to excellent in up to 93% of cases; however, this technique requires a two-stage procedure and can be cost-prohibitive. Particulated juvenile cartilage is a restorative technique that employs cartilage allograft from juvenile donors. The cartilage is placed into the defect and secured with fibrin glue in a single-stage procedure. Studies have shown favorable outcomes in 92% of cases, with lesions between 10 and 15 mm in diameter, but increased failure rates and poorer outcomes in lesions larger than 15 mm. This may be an alternative option for contained lesions between 10 and 15 mm in diameter. Osteochondral allograft plugs are an option for larger contained lesions (>1.5 cm in diameter) and in patients with knee osteoarthritis (OA) and concern for donor site morbidity. Furthermore, bulk osteochondral allograft from a size-matched talus can also be used for even larger, unstable/uncontained shoulder lesions. An anterior approach is often employed and fixation is achieved via placement of countersunk headless compression screws. Failure of the aforementioned options associated with persistent pain or progressive OA would then lend consideration to ankle arthroplasty versus ankle arthrodesis., (Published by Elsevier Inc.)- Published
- 2021
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37. Augmented Spring Ligament Repair in Pes Planovalgus Reconstruction.
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Fogleman JA, Kreulen CD, Sarcon AK, Michelier PV, Giza E, and Doty JF
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- Foot, Humans, Ligaments, Articular diagnostic imaging, Ligaments, Articular surgery, Radiography, Sutures, Flatfoot diagnostic imaging, Flatfoot surgery
- Abstract
Patients with pes planovalgus deformity often have coexisting spring ligament pathology. A primary repair of the ligament may fail during weightbearing due to chronic degeneration of the ligamentous tissue. Augmentation with a suture tape has been suggested to strengthen the repair. Limited data exist regarding flatfoot reconstruction with augmented spring ligament repair using a suture tape. This is a review of 57 consecutive patients who had flatfoot reconstruction with concomitant spring ligament augmented repair between July 2014 and August 2017. Weightbearing radiographic parameters were obtained preoperatively and compared to radiographs at an average time of 62 ± 46.5 (range 20-220) weeks postoperative. Significant improvements were seen in the radiographic parameters evaluated. Five patients had subsequent operations including one deep infection, 2 hardware removals remote to the spring ligament augmentation, 1 ankle arthrodesis, and 1 triple arthrodesis. Concomitant spring ligament repair augmented with a suture tape was a safe procedure that contributed to radiographic correction in a consecutive series of 57 patients undergoing flatfoot deformity correction., (Copyright © 2021 the American College of Foot and Ankle Surgeons. Published by Elsevier Inc. All rights reserved.)
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- 2021
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38. The impact of the Covid-19 pandemic on a Greek cohort of patients with epilepsy.
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Giza E, Lefkopoulou M, Dimitrakopoulos D, Karachristianou S, and Liasidis C
- Abstract
Background: The Covid-19 pandemic, the subsequent lockdown, and the measures of social distancing may have had adverse effects on patients with epilepsy (PWE). This study was designed to assess the pandemic's psychological impact on the Greek non-infected PWE and possible changes in their seizure control., Method: The patients were evaluated utilizing a semi-structured interview consisting of open questions regarding their demographic, social, and clinical characteristics, followed by five questions (on a scale of 0-10) related to the Covid-19 pandemic, lockdown, and social distancing measures. Anxiety and depression of PWE were screened using the Hospital Anxiety and Depression Scale (HADS), which consists of HADS-Anxiety and HADS-Depression subscales., Results: We evaluated 65 PWE in the outpatient clinic (60 %) or via telephone interview (40 %). None of these patients experienced changes in seizure control. The mean scores of the Covid-19-related questions were 6.1 ± 2.7 (fear of getting infected), 4.7 ± 3.3 (fear of death), 7.1 ± 2.7 (fear of sickness for their relatives), 6.4 ± 3.1 (stress during lockdown), and 3.0 ± 2.9 (fear of antiepileptic drugs unavailability). Thirty-nine (60 %) patients screened positive for anxiety and thirty-three (50.8 %) for depression., Conclusion: The psychological impact of the Covid-19 pandemic, lockdown, and social distancing measures on non-infected PWE was moderate without changes in their seizure control. HIPPOKRATIA 2021, 25 (4):145-150., (Copyright 2021, Hippokratio General Hospital of Thessaloniki.)
- Published
- 2021
39. Outcomes of Surgically Treated Fifth Metatarsal Fractures in Major League Soccer Athletes.
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Stone JA, Miranda AD, Gerhardt MB, Mandelbaum BR, and Giza E
- Subjects
- Athletes, Humans, Foot Injuries surgery, Fractures, Bone epidemiology, Fractures, Bone surgery, Metatarsal Bones surgery, Soccer
- Abstract
Background: Sports-related fractures of the fifth metatarsal are common in professional athletes. Data regarding outcomes of surgical management including refracture, complications, and return-to-play statistics are available for other professional American sports with a notable exception of soccer., Purpose: To quantify the burden of operative fifth metatarsal fractures in Major League Soccer (MLS) athletes, to compare outcomes as well as refracture and complication rates with other professional sports, to analyze factors that may contribute to treatment failure, and to report on return-to-play characteristics for affected players., Study Design: Case series; Level of evidence, 4., Methods: We searched all injuries in the prospectively collected HealtheAthlete database for MLS for operative fifth metatarsal fractures for seasons 2013 to 2017. Additional information regarding each fracture including demographics, treatment, postoperative course, and return-to-play statistics were compiled from HealtheAthlete and supplemented by teams' chief medical officers, coaches, trainers, and online sources., Results: There were 21 fractures in 18 players during the study period. Mean time to radiographic healing was 8.5 weeks (n = 17). Mean time to return to play was 11.1 weeks (n = 19). Of 21 fractures, 20 (95%) players returned to sport. Of 18 players, 4 (22.2%) experienced refracture. Of 18 players, 5 (27.8%) and 2 (11.1%) reported previous stress injuries on the contralateral and ipsilateral limb, respectively. Player performance characteristics showed small declines in the first year of return that improved by the second year., Conclusion: MLS athletes who sustain a sports-related fifth metatarsal fracture can expect a high rate of return to sport with time to radiographic healing and return to play as well as risk of refracture similar to other professional cohorts.
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- 2021
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40. Editorial Commentary: Drill and Fill: Bone Marrow Stimulation Plus Allograft Matrix May Optimize the Treatment of Osteochondral Lesions of the Talus.
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Delman CM, Kreulen C, and Giza E
- Subjects
- Allografts, Bone Marrow, Bone Transplantation, Humans, Cartilage, Articular surgery, Talus surgery
- Abstract
Osteochondral lesions of the talus remain a challenging pathologic entity facing orthopaedic foot and ankle surgeons. Although multiple treatment options exist, there is limited evidence supporting one technique over another. The ultimate goal of surgical intervention is to achieve lesion infill with tissue properties that best mimic those of hyaline articular cartilage. Restoring the anatomic surface of the talus may provide long-term clinical success and improve function. Augmentation of bone marrow stimulation with extracellular matrix cartilage allograft aims to achieve this goal., (Copyright © 2021 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved.)
- Published
- 2021
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41. Effect of Postoperative Oral Antibiotics on Infections and Wound Healing Following Foot and Ankle Surgery.
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Carl J, Shelton TJ, Nguyen K, Leon I, Park J, Giza E, and Kreulen C
- Subjects
- Adult, Female, Humans, Male, Middle Aged, Postoperative Period, Retrospective Studies, Anti-Bacterial Agents therapeutic use, Foot Joints surgery, Postoperative Complications prevention & control, Surgical Wound Infection prevention & control, Wound Healing drug effects
- Abstract
Background: There is controversy regarding the effectiveness of postoperative antibiotics to prevent wound infection. Some surgeons still use a routine postoperative oral antibiotic regimen. The purpose of this study was to review a series of cases and document statistically any difference in infection rates and whether routine postoperative antibiotics in foot and ankle surgery are justified., Methods: A retrospective chart review of 649 patients was performed who underwent elective foot and ankle surgery. Six hundred thirty-one patient charts were included in the final analysis. Evaluated were patients who did and did not receive postoperative oral antibiotics in order to identify whether a difference in infection rate or wound healing occurred. The study also evaluated risk factors for developing infection following foot and ankle surgery., Results: The number of infections in patients receiving postoperative oral antibiotics was 6 (3%), while the number of infections in those who did not receive postoperative oral antibiotics was 10 (2%) ( P = .597). The difference of deep versus superficial infections and delays in wound healing between the 2 groups was not statistically significant. Patients who developed infections were older and had a higher prevalence of hypertension, a history of neoplasm, and a greater American Society of Anesthesiologists Classification of Physical Health., Conclusion: This study suggests that routine use of postoperative antibiotics in foot and ankle surgery does not affect wound complications or infection rates. Additionally, patients who are older and those with multiple medical problems may be at higher risk for developing postoperative infection following foot and ankle surgeries., Level of Evidence: Level III, retrospective comparative series.
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- 2020
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42. Anterior Syndesmotic Augmentation Technique Using Nonabsorbable Suture-Tape for Acute and Chronic Syndesmotic Instability.
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Kwon JY, Stenquist D, Ye M, Williams C, Giza E, Kadakia AR, and Kreulen C
- Subjects
- Bone Screws, Humans, Suture Techniques, Sutures, Fibula surgery, Lateral Ligament, Ankle surgery
- Abstract
Syndesmotic instability is a source of significant pain and disability. Both subtle instability and gross diastasis, whether acute or chronic, require stabilization and may benefit from reconstruction with ligamentous augmentation. The use of nonabsorbable suture-tape has emerged as a promising operative strategy, allowing surgeons to anatomically reconstruct the syndesmosis, in particular the anterior inferior tibiofibular ligament. The current work provides a detailed description of the technique and preliminary results of a patient cohort treated using nonabsorbable suture-tape for syndesmotic augmentation. Level of Evidence: Level V, expert opinion.
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- 2020
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43. Crossed renal ectopia with fusion in a pelvic inlet area, atypical portal vein and coccygeal deformation in a young female cat.
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Hebel M, Ruszkowski JJ, Giza E, and Pomorska-Mól M
- Subjects
- Animals, Cat Diseases diagnostic imaging, Cats, Coccyx abnormalities, Diagnosis, Differential, Female, Kidney diagnostic imaging, Kidney Diseases congenital, Portal Vein abnormalities, Tomography, X-Ray Computed veterinary, Ultrasonography veterinary, Urography veterinary, Cat Diseases congenital, Kidney abnormalities, Kidney Diseases veterinary
- Abstract
Background: The case report describes a rare congenital anomaly, crossed fused renal ectopia (CFRE), with coexistence of two other abnormalities - atypical portal vein and coccygeal vertebrae malformation in a domestic cat. The concomitance of those 3 congenital defects has not been described previously., Case Presentation: An 8-month-old female, domestic cat suffering from chronic diarrhea was referred to the diagnostic imaging unit. The patient showed no other clinical symptoms. An abdominal ultrasonographic examination was performed in order to evaluate the condition of abdominal organs, particularly the gastrointestinal tract. The ultrasound examination showed an ectopic duplex kidney at instead of kidneys in their typical location. Computed tomography (CT) with angiographic phase and excretory urography was requested to evaluate the condition of the kidneys and ureters. The final diagnosis was CFRE, atypical portal vein and coccygeal deformation in an asymptomatic cat with no changes in renal function and normal blood parameters., Conclusions: Crossed fused renal ectopia is a rare congenital anomaly and is easily detectable by an abdominal ultrasonographic examination and CT, which allows more complete assessment of both anatomical relations and secretory function of the kidney. The occurrence of CFRE, abnormal portal vein and spinal malformation in a clinically healthy patient is the evidence that congenital malformations may simultaneously involve various, not directly related structures and systems, without significant influence on blood and urine parameters. Thus the most useful tool in the evaluation of the morphological and functional changes is the diagnostic imaging, especially contrast enhanced CT. Our results show that renal fusions should be considered in the differential diagnosis of caudal abdominal masses.
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- 2020
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44. Subchondroplasty of the Ankle and Hindfoot for Treatment of Osteochondral Lesions and Stress Fractures: Initial Imaging Experience.
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McWilliams GD, Yao L, Simonet LB, Haysbert CW, Giza E, Kreulen CD, and Boutin RD
- Subjects
- Adult, Aged, Ankle diagnostic imaging, Cohort Studies, Female, Follow-Up Studies, Four-Dimensional Computed Tomography, Fractures, Stress diagnostic imaging, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Retrospective Studies, Young Adult, Ankle surgery, Foot surgery, Fractures, Stress surgery, Orthopedic Procedures methods
- Abstract
Objective: To describe the imaging findings of patients treated with subchondroplasty (SCP) of the ankle and hindfoot. Materials and Methods: Eighteen patients (10 men, 8 women; age mean 43.1 years [range 20.1-67.7 years]) underwent ankle and hindfoot SCP at a single center over a 14-month period. Imaging data were reviewed retrospectively by 2 radiologists by consensus interpretation, including preoperative radiography (18), computed tomography (CT) (11), and magnetic resonance imaging (MRI) (13) and postoperative radiography (10), CT (4), and MRI (6). Follow-up imaging was acquired 1 month to 1.6 years following SCP. Results: Indications for SCP included symptomatic bone marrow lesions (BMLs) secondary to an osteochondral lesion (OCL) (16/18) or stress fracture (2/18). While focal radiodensity related to the SCP procedure was retrospectively identifiable on postoperative radiography in all except 1 case (10/11), postprocedural findings were not described by the interpreting radiologist in 6/11 cases. On CT, the average injected synthetic calcium phosphate (CaP) volume was 1.15 cm
3 (SD = 0.33 cm3 ); mean CT attenuation of the injectate was 1220 HU (range 1058-1465 HU). In all patients who had pre- and postoperative MRI (5/18), BML size decreased on follow-up MRI. Extra-osseous extrusion of CaP was not seen on postoperative radiography, CT, or MRI. Conclusion: Physicians should be aware of the expanding preoperative indications and postoperative imaging findings of SCP, which is being performed with increasing frequency in the ankle and hindfoot. Levels of Evidence: Diagnostic, Level III: Retrospective cohort study.- Published
- 2020
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45. Effects of Micronized Cartilage Matrix on Cartilage Repair in Osteochondral Lesions of the Talus.
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Shieh AK, Singh SG, Nathe C, Lian E, Haudenschild DR, Nolta JA, Lee CA, Giza E, and Kreulen CD
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- Bone Marrow Cells, Humans, In Vitro Techniques, Mesenchymal Stem Cells, Proof of Concept Study, Extracellular Matrix transplantation, Hyaline Cartilage cytology, Talus cytology, Tissue Engineering methods, Tissue Scaffolds
- Abstract
Background: The repair of osteochondral lesions remains a challenge due to its poor vascularity and limited healing potential. Micronized cartilage matrix (MCM) is dehydrated, decellularized, micronized allogeneic cartilage matrix that contains the components of native articular tissue and is hypothesized to serve as a scaffold for the formation of hyaline-like tissue. Our objective was to demonstrate in vitro that the use of MCM combined with mesenchymal stem cells (MSCs) can lead to the formation of hyaline-like cartilage tissue in a single-stage treatment model., Design: In group 1 (no wash), 250 µL MCM was reconstituted in 150 µL Dulbecco's phosphate-buffered saline (DPBS) for 5 minutes. Group 2 (saline wash) included 250 µL MCM washed in 20 mL DPBS for 30 minutes, then aspirated to remove all DPBS and reconstituted in 150 µL DPBS. Group 3 (serum wash): 250µL MCM washed in 20 mL DPBS for 30 minutes, then aspirated and reconstituted in 150 µL fetal bovine serum. Each group was then added to 50 µL solution of MSC suspended in DPBS at a concentration of 1.2 × 10
6 cells/350 µL. After 3 weeks, the defects were extracted and sectioned to perform viability and histologic analyses., Results: Stem cells without rehydration of the MCM showed almost no viability whereas near complete cell viability was seen after rehydration with serum or saline solution, ultimately leading to chondrogenic differentiation and adhesion to the MCM particles., Conclusion: We have shown in this proof-of-concept in vitro study that MCM can serve as a scaffold for the growth of cartilage tissue for the treatment of osteochondral lesions.- Published
- 2020
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46. Comparison of Suture-Augmented Ligamentplasty to Transarticular Screws in a Lisfranc Cadaveric Model.
- Author
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Nery C, Baumfeld D, Baumfeld T, Prado M, Giza E, Wagner P, and Wagner E
- Subjects
- Adult, Cadaver, Humans, Bone Screws, Foot Bones injuries, Foot Bones surgery, Ligaments, Articular injuries, Ligaments, Articular surgery, Suture Techniques
- Abstract
Background: Lisfranc injuries represent a spectrum of trauma from high-energy lesions, with significant instability of the midfoot, to low-energy lesions, with subtle subluxations or instability without gross displacement. Recently, treatment options that allow for physiologic fixation of this multiplanar joint are being evaluated. The purpose of this study was to analyze the stability of a cadaveric Lisfranc injury model fixed with a novel suture-augmented neoligamentplasty in comparison with a traditional transarticular screw fixation construct., Methods: Twenty-four fresh-frozen, matched cadaveric leg and foot specimens (12 individuals younger than 65 years of age) were used for this study. Two different types of Lisfranc ligament injuries were tested: partial and complete. Two different methods of fixation were compared: transarticular screws and augmented suture ligamentplasty with FiberTape. Specimens were fixed to a rotation platform in order to stress the joints while applying 400 N of axial load and internal and external rotation. Six distances were measured and compared between the intact, injured, and fixed states with a 3D Digitizer arm, in order to evaluate the stability between them. Analysis of variance was used with P < .05 considered significant., Results: Using distribution graphs and analyzing the grouped data, it was observed that there was no difference between the 2 stabilization methods, but the augmented suture ligamentplasty presented lower variability and observed distance shortenings were more likely to be around the mean. The variability of the stabilization with screws was 2.9 times higher than that with tape ( P < .001)., Conclusion: We suggest that augmented suture ligamentplasty can achieve similar stability to classic transarticular screws, with less variability., Clinical Relevance: This cadaveric study adds new information on the debate about Lisfranc lesions treatment. Flexible fixations, such as the synthethic ligamentplasty used, can restore good stability such as conventional transarticular screws.
- Published
- 2020
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47. Use of Anatomical Landmarks in Ankle Arthroscopy to Determine Accuracy of Syndesmotic Reduction: A Cadaveric Study.
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Cassinelli SJ, Harris TG, Giza E, Kreulen C, Matheny LM, Robbins CM, and Clanton TO
- Subjects
- Cadaver, Humans, Ankle anatomy & histology, Ankle surgery, Ankle Injuries diagnosis, Ankle Injuries surgery, Arthroscopy
- Abstract
Background. The aim of this study was to determine the accuracy of ankle arthroscopy as a means for diagnosing syndesmotic reduction or malreduction and to determine anatomical landmarks for diagnosis. Methods. Six matched-pair cadavers (n = 12) with through-knee amputations were studied. Component parts of the syndesmosis and distal 10 cm of the interosseous membrane (IOM) were sectioned in each. The 12 specimens were divided into 2 groups: 6 specimens in the in-situ group fixed with suture button technique and 6 specimens in the malreduced group rigidly held with a 3.5-mm screw. Specimens were randomized to undergo diagnostic arthroscopy by 3 fellowship-trained foot and ankle orthopaedic surgeons in a blinded fashion. Surgeons were asked to determine if the syndesmosis was reduced or malreduced and provide arthroscopic measurements of their findings. Results. Of 36 arthroscopic evaluations, 34 (94%) were correctly diagnosed. Arthroscopic measurement of 3.5 mm diastasis or greater at the anterior aspect of the distal tibiofibular syndesmosis correlated with a posteriorly malreduced fibula. Arthroscopic evaluation of the Anterior inferior tibiofibular ligament (AITFL), IOM, Posterior inferior tibiofibular ligament (PITFL), lateral fibular gutter, and the tibia/fibula relationship were found to be reliable landmarks in determining syndesmotic reduction. An intraclass correlation coefficient (ICC) for interrater reliability of 1.00 was determined for each of these landmarks between 2 surgeons (P < .001). The ICCs between 2 surgeons' measurements and the computed tomography measurements were found to be 0.896 (P value < .001). Conclusions. Ankle arthroscopy is a reliable method to assess syndesmotic relationship when reduced in situ or posteriorly malreduced 10 mm. Levels of Evidence: Level V: Cadaveric.
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- 2020
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48. Arthroscopic Anatomic Anterior Talofibular Ligament Repair for Anterolateral Ankle Instability.
- Author
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Malinowski K, Paszkowski J, Góralczyk A, Giza E, and Hermanowicz K
- Abstract
Ankle instability is due to repetitive inversion injuries and is usually treated conservatively; however, after repeated sprains, chronic instability occurs and usually requires a surgical procedure. Recently, arthroscopic repair of a torn anterior talofibular ligament (ATFL) has become more popular owing to its minimal invasiveness and high efficacy. An all-inside technique allows for anatomic restoration of the injured ATFL, provides stability to the ankle joint, prevents a limitation of ankle range of motion, and may prevent arthritic development. We present an all-inside arthroscopic ATFL repair technique., (© 2019 by the Arthroscopy Association of North America. Published by Elsevier.)
- Published
- 2019
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49. Tarsal Tunnel Syndrome Secondary to Accessory Musculature: A Case Report.
- Author
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Neary KC, Chang E, Kreulen C, and Giza E
- Subjects
- Humans, Male, Middle Aged, Muscle, Skeletal surgery, Nerve Compression Syndromes, Tarsal Tunnel Syndrome diagnostic imaging, Tarsal Tunnel Syndrome therapy, Tarsal Tunnel Syndrome etiology
- Abstract
Tarsal tunnel syndrome (TTS) is a relatively uncommon compression neuropathy caused by impingement of the tibial nerve or one of the terminal branches. The presence of accessory musculature at the posteromedial aspect of the ankle has been identified as a rare cause of this condition. Despite the rarity of this condition, it must be considered in patients with refractory symptoms consistent with tibial nerve dysfunction. The accurate diagnosis of this condition relies heavily on a detailed history and physical examination, adequate imaging read by both surgeon and trained musculoskeletal radiologist, as well as a high level of suspicion for such pathology. In this case report, we describe a 46-year-old male with history, examination, and imaging all consistent with TTS secondary to accessory musculature. Following excision of an accessory soleus and flexor digitorum accessorius longus, as well as simultaneous tarsal tunnel release, the patient experienced full resolution of his symptoms. This highlights the importance of considering accessory musculature as a potential cause of TTS in patients presenting with tibial compression neuropathy. Levels of Evidence: Level V: Case Report.
- Published
- 2019
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50. Functional rhythmic tongue movements.
- Author
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Giza E, Dagklis IE, Kimiskidis V, Katsarou Z, and Bostantjopoulou S
- Subjects
- Adult, Biperiden administration & dosage, Humans, Male, Tongue Diseases drug therapy, Tremor drug therapy, Valproic Acid administration & dosage, Anticonvulsants administration & dosage, Tongue Diseases physiopathology, Tremor physiopathology
- Published
- 2019
- Full Text
- View/download PDF
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