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18 results on '"Givone, Filippo"'

6. Effect of Lactoferrin on Clinical Outcomes of Hospitalized Patients with COVID-19: The LAC Randomized Clinical Trial

Author

Matino, Erica, primary, Tavella, Elena, additional, Rizzi, Manuela, additional, Avanzi, Gian Carlo, additional, Azzolina, Danila, additional, Battaglia, Antonio, additional, Becco, Paolo, additional, Bellan, Mattia, additional, Bertinieri, Giovanni, additional, Bertoletti, Massimo, additional, Casciaro, Giuseppe Francesco, additional, Castello, Luigi Mario, additional, Colageo, Umberto, additional, Colangelo, Donato, additional, Comolli, Davide, additional, Costanzo, Martina, additional, Croce, Alessandro, additional, D’Onghia, Davide, additional, Della Corte, Francesco, additional, De Mitri, Luigi, additional, Dodaro, Valentina, additional, Givone, Filippo, additional, Gravina, Alessia, additional, Grillenzoni, Luca, additional, Gusmaroli, Graziano, additional, Landi, Raffaella, additional, Lingua, Anna, additional, Manzoni, Roberto, additional, Marinoni, Vito, additional, Masturzo, Bianca, additional, Minisini, Rosalba, additional, Morello, Marina, additional, Nelva, Anna, additional, Ortone, Elena, additional, Paolella, Rita, additional, Patti, Giuseppe, additional, Pedrinelli, Anita, additional, Pirisi, Mario, additional, Ravizzi, Lidia, additional, Rizzi, Eleonora, additional, Sola, Daniele, additional, Sola, Mariolina, additional, Tonello, Nadir, additional, Tonello, Stelvio, additional, Topazzo, Gigliola, additional, Tua, Aldo, additional, Valenti, Piera, additional, Vaschetto, Rosanna, additional, Vassia, Veronica, additional, Zecca, Erika, additional, Zublena, Nicoletta, additional, Manzoni, Paolo, additional, and Sainaghi, Pier Paolo, additional

Published
2023
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8. Successful JC virus-targeted T-cell therapy for progressive multifocal leukoencephalopathy in a lung transplant recipient

Author

Peghin, Maddalena, primary, Castaldo, Nadia, additional, Tascini, Carlo, additional, Bassetti, Matteo, additional, Graziano, Elena, additional, Givone, Filippo, additional, Savignano, Chiara, additional, De Colle, Maria Cristina, additional, Bove, Tiziana, additional, Pipan, Corrado, additional, Loy, Monica, additional, Basso, Sabrina, additional, Cinque, Paola, additional, Gerevini, Simonetta, additional, Berastegui, Cristina, additional, Hirsch, Hans H., additional, Grossi, Paolo A., additional, and Comoli, Patrizia, additional

Published
2022
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13. Risk scores and surgery for infective endocarditis: in search of a good predictive score

Author

Gatti, Giuseppe, primary, Sponga, Sandro, additional, Peghin, Maddalena, additional, Givone, Filippo, additional, Ferrara, Veronica, additional, Benussi, Bernardo, additional, Mazzaro, Enzo, additional, Perrotti, Andrea, additional, Bassetti, Matteo, additional, Luzzati, Roberto, additional, Chocron, Sidney, additional, Pappalardo, Aniello, additional, and Livi, Ugolino, additional

Published
2019
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14. Ceftolozane/tazobactam for the treatment of serious Pseudomonas aeruginosa infections: a multicentre nationwide clinical experience

Author

Bassetti, Matteo, primary, Castaldo, Nadia, additional, Cattelan, Annamaria, additional, Mussini, Cristina, additional, Righi, Elda, additional, Tascini, Carlo, additional, Menichetti, Francesco, additional, Mastroianni, Claudio Maria, additional, Tumbarello, Mario, additional, Grossi, Paolo, additional, Artioli, Stefania, additional, Carannante, Novella, additional, Cipriani, Ludovica, additional, Coletto, Davide, additional, Russo, Alessandro, additional, Digaetano, Margherita, additional, Losito, Angela Raffaella, additional, Peghin, Maddalena, additional, Capone, Alessandro, additional, Nicolè, Stefano, additional, Vena, Antonio, additional, Bassetti, Matteo, additional, Pecori, Davide, additional, Carnellutti, Alessia, additional, Givone, Filippo, additional, Graziano, Elena, additional, Merelli, Maria, additional, Cadeo, Barbara, additional, Verdenelli, Stefano, additional, Fabiani, Silvia, additional, Gianluca, Russo, additional, Oliva, Alessandra, additional, Ciardi, Maria Rosa, additional, Ajassa, Camilla, additional, Tieghi, Tiziana, additional, Raffaelli, Francesca, additional, Rovelli, Cristina, additional, Caruana, Giorgia, additional, Luzzati, Roberto, additional, Bontempo, Giulia, additional, Petrosillo, Nicola, additional, Rizzardini, Giuliano, additional, Coen, Massimo, additional, Passerini, Matteo, additional, Mastroianni, Antonio, additional, Urso, Filippo, additional, Bianco, Maria Francesca, additional, Borgia, Guglielmo, additional, Gentile, Ivan, additional, Maraolo, Alberto Enrico, additional, Crapis, Massimo, additional, Venturini, Sergio, additional, Parruti, Giustino, additional, Trave, Francesca, additional, Angarano, Gioacchino, additional, Carbonara, Sergio, additional, Mariani, Michele Fabiano, additional, Girardis, Massimo, additional, Cascio, Antonio, additional, Gioé, Claudia, additional, Anselmo, Marco, additional, and Malfatto, Emanuele, additional

Published
2019
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17. Ceftolozane/tazobactam for the treatment of MDR <italic>Pseudomonas aeruginosa</italic> left ventricular assist device infection as a bridge to heart transplant.

Author

Peghin, Maddalena, Maiani, Massimo, Castaldo, Nadia, Givone, Filippo, Righi, Elda, Lechiancole, Andrea, Sartor, Assunta, Pea, Federico, Livi, Ugolino, and Bassetti, Matteo

Subjects
CEPHALOSPORINS, ENZYME inhibitors, AMIKACIN, AMINOGLYCOSIDES, ANTIBIOTICS, BLOOD, BLOOD vessels, CELL culture, CIPROFLOXACIN, COMPUTED tomography, DEOXY sugars, FEVER, GRAM-negative bacteria, LEFT heart ventricle, HEART transplantation, INFECTION, INTRAVENOUS therapy, MICROBIAL sensitivity tests, MULTIDRUG resistance, PATIENT safety, COMPLICATIONS of prosthesis, RADIOPHARMACEUTICALS, POSITRON emission tomography, DISEASE relapse, TERMINATION of treatment, HEART assist devices, COLISTIN, THERAPEUTICS
Abstract

Background: Ceftolozane/tazobactam (C/T) is a novel antibiotic with enhanced microbiological activity against multidrug-resistant (MDR) gram-negative bacteria, including MDR Pseudomonas aeruginosa.Case report: Five months after left ventricular assist device (LVAD) implantation, a 49-year old man developed fever and blood culture was positive for MDR P. aeruginosa, susceptible only to aminoglycosides, ciprofloxacin and colistin. A diagnosis of LVAD-related infection was made based on persistent bacteremia associated with moderate 18 F-fluorodeoxyglucose positron emission tomography/CT uptake in the left ventricular apex. Disk diffusion testing for C/T was performed (MIC 2 μg/mL) and intravenous antibiotic therapy with C/T and amikacin was started, with clinical and microbiological response. Initial conservative management with 6 weeks of systemic antibiotic therapy was attempted, but the patient relapsed one month after antibiotic discontinuation. Priority for transplantation was given and after 4 weeks of antibiotic therapy (C/T + amikacin), LVAD removal and heart transplant were performed, with no infection relapse.Conclusions: We reported the first off-label use of C/T in the management of MDR P. aeruginosa LVAD infection as a bridge to heart transplant. C/T has shown potent anti-pseudomonal activity and good safety profile making this drug as a good candidate for suppressive strategy in intravascular device-associated bloodstream infections caused by MDR P. aeruginosa. [ABSTRACT FROM AUTHOR]

Published
2018
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18. Multidrug-resistant Pseudomonas aeruginosaskin and soft-tissue infection successfully treated with ceftolozane/tazobactam

Author

Castaldo, Nadia, Givone, Filippo, Peghin, Maddalena, Righi, Elda, Sartor, Assunta, and Bassetti, Matteo

Abstract

•Ceftolozane/tazobactam (C/T) is a novel β-lactam/β-lactamase inhibitor combination.•Case of multidrug-resistant (MDR) P. aeruginosa skin and soft-tissue infection (SSTI) successfully treated with C/T.•C/T may be a valid treatment option for MDR P. aeruginosa SSTI, sparing carbapenems, polymyxins and aminoglycosides.

Published
2017
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